mRRPE(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 63 13

    EXPR: (0.157) mRRPE (P < 0.000) PAC (P < 0.000)

ORFSYMBOLPFCTF
|YIL122W|POG1re-entry into mitotic cell cycle after pheromone arrest ->
cell growth and/or maintenance, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus
specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity
nucleus ->
nucleus
ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YJL148WRPA34transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex, nucleus, nucleolus ->
nucleus
AZF1, CHA4, CUP9, DAL81, DIG1, FZF1, GCR1, GCR2, GLN3, HAL9, HAP2, HAP3, HMS1, LEU3, MAC1, MBP1, MET31, MOT3, NDD1, PDR1, PHD1, REB1, RLM1, RME1, ROX1, RPH1, RTS2, SKN7, SWI5, YAP6, ZAP1
YGR245CSDA1actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell growth and/or maintenance
nucleus ->
nucleus
YNL110CNOP15ribosomal large subunit biogenesis ->
cell growth and/or maintenance
nucleus, nucleolus ->
nucleus
YJL050WMTR435S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
YDR399WHPT1purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
YMR131CRRB1ribosome biogenesis ->
cell growth and/or maintenance
nucleolus ->
nucleus
FZF1, MATa1, RGT1
YAL059WECM1cell wall organization and biogenesis ->
cell growth and/or maintenance
MOT3
YLR197WSIK1rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex
DAL81, HAL9
|YPR183W|DPM1N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system
SWI5
YOR078WBUD21processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, MSS11, SIG1, SKO1
YNL209WSSB2protein biosynthesis ->
biosynthesis, protein metabolism
chaperone activity, ATPase activity ->
chaperone activity, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
polysome, cytoplasm ->
cytoplasm, ribonucleoprotein complex
ABF1, RFX1
YHR169WDBP835S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
YOR272WYTM1chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis ->
cell growth and/or maintenance
nucleus, nucleolus ->
nucleus
LEU3, PUT3, REB1
YMR229CRRP5rRNA processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding, snoRNA binding ->
RNA binding
nucleolus, nucleolus organizer complex ->
nucleus
FHL1, RAP1
|YKL014C|NO SYMBOLABF1
YGR159CNSR1ribosomal small subunit assembly and maintenance, rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
single-stranded DNA binding, RNA binding ->
DNA binding, RNA binding
nucleolus, nucleus ->
nucleus
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation factor activity\, nucleic acid binding
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YGR187CHGH1ABF1, HAP3, HIR1, RCS1, RTG1
YMR014WBUD22bud site selection ->
cell growth and/or maintenance
nucleus ->
nucleus
CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YJR002WMPP10rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YPR144CNOC4ribosome biogenesis ->
cell growth and/or maintenance
nucleus ->
nucleus
HIR1
YGR272CNO SYMBOLREB1, STP2
YFR001WLOC1ribosomal large subunit biogenesis ->
cell growth and/or maintenance
mRNA binding ->
RNA binding
nucleus ->
nucleus
ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
YGL078CDBP3ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
YDR101CARX1ribosomal large subunit biogenesis ->
cell growth and/or maintenance
nucleoplasm, cytoplasm ->
nucleus, cytoplasm
IXR1, RFX1
|YML125C|NO SYMBOLMAL13, MSN4, NDD1, RME1, SWI5
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
|YJL069C|UTP18ABF1
YGL029WCGR1ribosome biogenesis, rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleolus ->
nucleus
YHR052WCIC1protein catabolism ->
catabolism, protein metabolism
protein binding\, bridging ->
protein binding\, bridging
nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm
HAP4, MATa1
|YDR279W|RNH202GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YMR310CNO SYMBOL
YNR046WNO SYMBOLABF1
|YNL292W|PUS4tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
pseudouridylate synthase activity ->
carbon-oxygen lyase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
YNR024WNO SYMBOL
|YMR259C|NO SYMBOLARG80, GCR2, GTS1, HIR1, SRD1
YHR196WUTP9processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YNR053CNOG2mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleus, nucleolus, nucleoplasm ->
nucleus, nucleoplasm
ABF1, AZF1
YGR145WENP2
YGL171WROK135S primary transcript processing, mRNA splicing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity, ATPase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
RGT1
|YGL016W|KAP122protein-nucleus import, response to drug ->
response to abiotic stimulus, protein metabolism, cell growth and/or maintenance
protein carrier activity ->
protein carrier activity
cytoplasm, nuclear pore ->
cytoplasm, nucleus, integral to membrane, endomembrane system
MSN2
YLR276CDBP9ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
MATa1, RCS1, RTG3, SWI5
YKL172WEBP2rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleolus ->
nucleus
ABF1, FZF1, RFX1
YDR449CUTP6processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YPL043WNOP4rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
YKL056CNO SYMBOL
YGR162WTIF4631translational initiation ->
biosynthesis, protein metabolism
translation initiation factor activity ->
translation factor activity\, nucleic acid binding
ribosome ->
cytoplasm, ribonucleoprotein complex
HSF1
YGL169WSUA5cell growth and/or maintenance ->
cell growth and/or maintenance
ABF1
YML093WUTP14processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YPL266WDIM1rRNA modification, 35S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
rRNA (adenine-N6\,N6-)-dimethyltransferase activity ->
transferase activity\, transferring one-carbon groups
nucleolus ->
nucleus
ARG81, STP2
|YOR381W|FRE3iron-siderochrome transport, iron ion homeostasis ->
cell growth and/or maintenance
ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions
plasma membrane, integral to membrane ->
plasma membrane, integral to membrane
CIN5, PDR1, YAP6
YJL109CUTP10processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YDR161WNO SYMBOL
YMR239CRNT135S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ribonuclease III activity ->
hydrolase activity\, acting on ester bonds, RNA binding
nucleolus ->
nucleus
YJL033WHCA435S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
HIR2, USV1
YGL099WLSG1conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, protein metabolism, cell growth and/or maintenance, sexual reproduction
GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
cytoplasm ->
cytoplasm
PHO4
|YJL138C|TIF2translational initiation, regulation of translational initiation ->
biosynthesis, protein metabolism
translation initiation factor activity, RNA helicase activity ->
translation factor activity\, nucleic acid binding, RNA binding
ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex
PHD1
YNL075WIMP4rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
rRNA primary transcript binding ->
RNA binding
small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
USV1
YNL175CNOP13RNA binding ->
RNA binding
nucleolus, nucleoplasm ->
nucleus
INO2, INO4
YOL022CNO SYMBOLMAC1, MOT3, RTS2
|YMR049C|ERB1rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RTG3
YDR496CPUF6RFX1
YNL112WDBP2RNA helicase activity ->
RNA binding
bud neck ->
site of polarized growth (sensu Fungi)
YNL308CKRI1ribosome biogenesis ->
cell growth and/or maintenance
nucleolus ->
nucleus
YBR247CENP1processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
nucleolus, nucleus ->
nucleus
YDR365CNO SYMBOLABF1, MSS11, YJL206C
YJR070CNO SYMBOLGAT3, YAP5
YLR222CUTP13processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1
YOR095CRKI1pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism
ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity
FHL1, FKH2, RAP1
|YOR359W|VTS1protein-vacuolar targeting ->
protein metabolism, cell growth and/or maintenance
intracellular transporter activity ->
intracellular transporter activity
cytosol ->
cytoplasm
RAP1
YNL132WKRE33
YMR290CHAS1nucleolus, nuclear membrane ->
nucleus, endomembrane system
RAP1
YGR280CPXR135S primary transcript processing, snRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
YDR184CATC1response to stress, polar budding ->
response to stress, asexual reproduction
nucleus ->
nucleus
ARO80, GLN3, SIP4, SKO1
Main:cell growth and/or maintenance (0.76)RNA binding (0.57)nucleus (0.83)ABF1 (0.23)
Score:0.700.360.750.114
P-value:5.177E-29 (ribosome biogenesis)2.275E-08 (snoRNA binding)2.137E-32 (nucleolus)3.563E-01 (ABF1)

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YGR280C) OR SimExpr(other) : 16 4

    EXPR: (0.148) mRRPE (P < 0.000) PAC (P < 0.000) SCB (P < 0.000)

ORFSYMBOLPFCTF
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YDR399WHPT1purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
YMR131CRRB1ribosome biogenesis ->
cell organization and biogenesis
nucleolus ->
nucleus
FZF1, MATa1, RGT1
YLR197WSIK1rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex
DAL81, HAL9
YOR078WBUD21processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, MSS11, SIG1, SKO1
YGR159CNSR1ribosomal small subunit assembly and maintenance, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
single-stranded DNA binding, RNA binding ->
DNA binding, RNA binding
nucleolus, nucleus ->
nucleus
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation factor activity\, nucleic acid binding
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YPR144CNOC4ribosome biogenesis ->
cell organization and biogenesis
nucleus ->
nucleus
HIR1
|YJL069C|UTP18ABF1
YHR052WCIC1protein catabolism ->
catabolism, protein metabolism
protein binding\, bridging ->
protein binding\, bridging
nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm
HAP4, MATa1
|YNL292W|PUS4tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
pseudouridylate synthase activity ->
carbon-oxygen lyase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
|YMR259C|NO SYMBOLARG80, GCR2, GTS1, HIR1, SRD1
YKL056CNO SYMBOL
YJL109CUTP10processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YMR239CRNT135S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ribonuclease III activity ->
hydrolase activity\, acting on ester bonds, RNA binding
nucleolus ->
nucleus
|YJL138C|TIF2translational initiation, regulation of translational initiation ->
biosynthesis, protein metabolism
translation initiation factor activity, RNA helicase activity ->
translation factor activity\, nucleic acid binding, RNA binding
ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex
PHD1
YNL112WDBP2RNA helicase activity ->
RNA binding
bud neck ->
site of polarized growth (sensu Fungi)
YJR070CNO SYMBOLGAT3, YAP5
YGR280CPXR135S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
YDR184CATC1response to stress, polar budding ->
response to stress, asexual reproduction
nucleus ->
nucleus
ARO80, GLN3, SIP4, SKO1
Main:cell organization and biogenesis (0.60)RNA binding (0.64)nucleus (0.80)ABF1 (0.23)
Score:0.530.400.750.077
P-value:6.748E-07 (ribosome biogenesis)5.928E-03 (RNA binding)2.222E-07 (nucleolus)4.089E-01 (SKO1)

mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGR280C) OR SimExpr(other) : 10 4

    EXPR: (0.162) mRRPE (P < 0.000) PAC (P < 0.021) MCM1' (P < 0.000)

ORFSYMBOLPFCTF
|YIL122W|POG1re-entry into mitotic cell cycle after pheromone arrest ->
cell growth and/or maintenance, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus
specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity
nucleus ->
nucleus
ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YDR399WHPT1purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
YGR159CNSR1ribosomal small subunit assembly and maintenance, rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
single-stranded DNA binding, RNA binding ->
DNA binding, RNA binding
nucleolus, nucleus ->
nucleus
|YML125C|NO SYMBOLMAL13, MSN4, NDD1, RME1, SWI5
YGL029WCGR1ribosome biogenesis, rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleolus ->
nucleus
|YDR279W|RNH202GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YPL043WNOP4rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
YGL169WSUA5cell growth and/or maintenance ->
cell growth and/or maintenance
ABF1
YML093WUTP14processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YMR049C|ERB1rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RTG3
YDR365CNO SYMBOLABF1, MSS11, YJL206C
YOR095CRKI1pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism
ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity
FHL1, FKH2, RAP1
YGR280CPXR135S primary transcript processing, snRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
Main:cell growth and/or maintenance (0.82)RNA binding (0.57)nucleus (1.00)ABF1 (0.38)
Score:0.780.291.000.179
P-value:8.451E-07 (rRNA processing)1.217E-01 (RNA binding)6.765E-05 (nucleolus)9.683E-01 (RLM1)

mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 11 5

    EXPR: (0.178) mRRPE (P < 0.006) SWI5 (P < 0.000) PAC (P < 0.095)

ORFSYMBOLPFCTF
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YGR245CSDA1actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation
nucleus ->
nucleus
YDR399WHPT1purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
|YPR183W|DPM1N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system
SWI5
YMR229CRRP5rRNA processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding, snoRNA binding ->
RNA binding
nucleolus, nucleolus organizer complex ->
nucleus
FHL1, RAP1
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation factor activity\, nucleic acid binding
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YJR002WMPP10rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YFR001WLOC1ribosomal large subunit biogenesis ->
cell organization and biogenesis
mRNA binding ->
RNA binding
nucleus ->
nucleus
ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
|YML125C|NO SYMBOLMAL13, MSN4, NDD1, RME1, SWI5
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
|YDR279W|RNH202GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YNR024WNO SYMBOL
|YMR259C|NO SYMBOLARG80, GCR2, GTS1, HIR1, SRD1
|YGL016W|KAP122protein-nucleus import, response to drug ->
response to abiotic stimulus, protein metabolism, transport
protein carrier activity ->
protein carrier activity
cytoplasm, nuclear pore ->
cytoplasm, nucleus, integral to membrane, endomembrane system
MSN2
YJL109CUTP10processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YGR280CPXR135S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
Main:cell organization and biogenesis (0.58)RNA binding (0.44)nucleus (0.82)GCR2 ARG80 RLM1 MSN2 SWI5 MSN4 SWI6 HIR1 GTS1 (0.20)
Score:0.560.190.760.156
P-value:2.329E-04 (processing of 20S pre-rRNA)4.169E-02 (snoRNA binding)2.538E-04 (nucleolus)8.743E-02 (MSN2)

REB1(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 5 2

    EXPR: (0.150) REB1 (P < 0.000) PAC (P < 0.026)

ORFSYMBOLPFCTF
YOR272WYTM1chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis ->
chromosome organization and biogenesis (sensu Eukarya), ribosome biogenesis
nucleus, nucleolus ->
nucleus, nucleolus
LEU3, PUT3, REB1
YOR021CNO SYMBOLARG80, GCR2
YPL266WDIM1rRNA modification, 35S primary transcript processing ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter
rRNA (adenine-N6\,N6-)-dimethyltransferase activity ->
rRNA (adenine-N6\,N6-)-dimethyltransferase activity
nucleolus ->
nucleolus
ARG81, STP2
|YKL142W|MRP8protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
mitochondrial ribosome ->
mitochondrial matrix, organellar ribosome
ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YNL308CKRI1ribosome biogenesis ->
ribosome biogenesis
nucleolus ->
nucleolus
|YML043C|RRN11transcription from Pol I promoter ->
transcription from Pol I promoter
RNA polymerase I transcription factor activity ->
RNA polymerase I transcription factor activity
RNA polymerase I transcription factor complex ->
nucleolus, transcription factor complex
MAL13
YGR280CPXR135S primary transcript processing, snRNA processing ->
ribosome biogenesis, snRNA processing, RNA processing, transcription from Pol I promoter
RNA binding ->
RNA binding
nucleolus ->
nucleolus
Main:ribosome biogenesis (0.67)RNA binding (0.25)nucleolus (0.83)REB1 (0.40)
Score:0.530.000.670.100
P-value:1.591E-03 (ribosome biogenesis)2.000E+001.148E-05 (nucleolus)3.778E-01 (REB1)

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 7 1

    EXPR: (0.135) LYS14 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.002)

ORFSYMBOLPFCTF
YNL110CNOP15ribosomal large subunit biogenesis ->
cytoplasm organization and biogenesis
nucleus, nucleolus ->
nucleus
YHR052WCIC1protein catabolism ->
macromolecule catabolism, protein metabolism
protein binding\, bridging ->
protein binding\, bridging
nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm
HAP4, MATa1
|YMR259C|NO SYMBOLARG80, GCR2, GTS1, HIR1, SRD1
YML093WUTP14processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YGL099WLSG1conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation with cellular fusion, sporulation (sensu Fungi), cytoplasm organization and biogenesis, intracellular transport, protein metabolism, protein transport
GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
cytoplasm ->
cytoplasm
PHO4
YJR070CNO SYMBOLGAT3, YAP5
YMR290CHAS1nucleolus, nuclear membrane ->
nucleus, endomembrane system
RAP1
YGR280CPXR135S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription
RNA binding ->
RNA binding
nucleolus ->
nucleus
Main:cytoplasm organization and biogenesis (0.80)RNA binding (0.50)nucleus (0.83)GCR2 (0.20)
Score:0.700.170.730.000
P-value:3.082E-03 (ribosome biogenesis)6.400E-01 (RNA binding)3.460E-05 (nucleolus)9.544E-01 (MATa1)

RAP1(1) AND MCM1'(1) => SimExpr(YOL120C) OR SimExpr(other) : 15 6

    EXPR: (0.133) MCM1' (P < 0.000) RAP1 (P < 0.035)

ORFSYMBOLPFCTF
YGL147CRPL9Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MBP1, RAP1, SWI4
|YKL033W|NO SYMBOLRPH1
YGL030WRPL30protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation ->
cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytosol, cytoplasm, ribosome
FHL1, GAT3, RAP1, SFP1
YGR214WRPS0Aprotein biosynthesis, ribosomal small subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, RAP1
YGR085CRPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MIG1
YMR230WRPS10Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, RAP1
YDL130WRPP1Bprotein biosynthesis, translational elongation ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAL4, RAP1, RFX1
YIL018WRPL2Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5
|YGR254W|ENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytosol, cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
|YKL152C|GPM1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphoglycerate mutase activity ->
phosphoglycerate mutase activity
cytosol ->
cytosol
GCR1, GCR2, HSF1, RAP1
YKL006WRPL14Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
YML073CRPL6Aprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1, YAP5
YNL069CRPL16Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YOL120CRPL18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MAL13, RAP1, YAP5
|YPL180W|BIT89glycerol metabolism ->
alcohol metabolism, glycerol ether metabolism, lipid metabolism
REB1, RGT1, SIG1
YDR450WRPS18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YLR344WRPL26Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, RAP1
|YLR452C|SST2signal transduction, adaptation to pheromone during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus
GTPase activator activity ->
GTPase activator activity
plasma membrane ->
plasma membrane
DIG1, FHL1, RAP1, STE12
YPL090CRPS6Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, GAT3, INO4, RAP1, YAP5
|YJR139C|HOM6homoserine biosynthesis, methionine metabolism, threonine metabolism ->
amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism
homoserine dehydrogenase activity ->
homoserine dehydrogenase activity
HMS1, RAP1
YMR142CRPL13Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1, RGM1, YAP5
Main:biosynthesis (0.90)structural constituent of ribosome (0.79)cytosol (0.94)RAP1 (0.81)
Score:0.820.610.890.752
P-value:5.067E-09 (protein biosynthesis)6.126E-14 (structural constituent of ribosome)8.148E-16 (cytosolic ribosome (sensu Eukarya))3.243E-20 (FHL1)

RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YOL120C) OR SimExpr(other) : 6 2

    EXPR: (0.133) ALPHA1' (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.129)

ORFSYMBOLPFCTF
|YKL033W|NO SYMBOLRPH1
YGR214WRPS0Aprotein biosynthesis, ribosomal small subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, RAP1
YDL130WRPP1Bprotein biosynthesis, translational elongation ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAL4, RAP1, RFX1
|YGR254W|ENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytosol, cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
YOL120CRPL18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MAL13, RAP1, YAP5
YLR344WRPL26Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, RAP1
YPL090CRPS6Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, GAT3, INO4, RAP1, YAP5
YMR142CRPL13Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1, RGM1, YAP5
Main:biosynthesis (1.00)structural constituent of ribosome (0.86)cytosol (1.00)RAP1 FHL1 (0.75)
Score:1.000.711.000.643
P-value:3.960E-04 (protein biosynthesis)4.603E-06 (structural constituent of ribosome)2.692E-06 (cytosolic ribosome (sensu Eukarya))2.046E-07 (FHL1)

MCM1(1) AND STRE(1) => SimExpr(YKL035W) OR SimExpr(other) : 5 1

    EXPR: (0.148) STRE (P < 0.002) MCM1 (P < 0.000)

ORFSYMBOLPFCTF
|YJL079C|PRY1nuclear membrane, endoplasmic reticulum ->
nuclear membrane, endoplasmic reticulum
NDD1, PHD1, RAP1
YJL082WIML2
YLR201CNO SYMBOLABF1
YMR291WNO SYMBOLRAP1
YKL035WUGP1protein amino acid glycosylation, UDP-glucose metabolism ->
protein amino acid glycosylation, UDP-glucose metabolism
UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
YOL087CNO SYMBOLDAL82
Main:protein amino acid glycosylation (1.00)UTP-glucose-1-phosphate uridylyltransferase activity (1.00)endoplasmic reticulum (1.00)RAP1 (0.50)
Score:0.000.000.000.167
P-value:0.000E+000.000E+000.000E+002.350E-01 (RAP1)

CSRE(1) AND PHO4(1) => SimExpr(YML117W) OR SimExpr(other) : 5 1

    EXPR: (0.144) PHO4 (P < 0.007) CSRE (P < 0.000)

ORFSYMBOLPFCTF
YML117WNAB6
YOR299WBUD7bud site selection ->
cell proliferation, cell organization and biogenesis
HSF1, MTH1
YOR185CGSP2nuclear organization and biogenesis ->
cell organization and biogenesis
RAN small monomeric GTPase activity ->
RAN small monomeric GTPase activity
nucleus ->
nucleus
YFL004WVTC2protein localization, vacuole fusion (non-autophagic) ->
protein metabolism, cell organization and biogenesis
vacuolar membrane ->
cytoplasm
CIN5, GCN4, STE12, YAP1, YAP6
YJL042WMHP1microtubule stabilization, cell wall organization and biogenesis ->
cell organization and biogenesis
structural constituent of cytoskeleton ->
structural constituent of cytoskeleton
microtubule ->
cytoplasm
CRZ1, GAL4, GAT3, PDR1, RGM1, YAP5
|YPL190C|NAB3regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
poly(A) binding ->
poly(A) binding
nucleoplasm ->
nucleus
RFX1
Main:cell organization and biogenesis (0.80)poly(A) binding (0.33)cytoplasm (0.50)MTH1 (0.25)
Score:0.600.000.330.000
P-value:3.488E-01 (organelle organization and biogenesis)1.794E+00 (binding)4.104E+00 (nucleus)5.520E-01 (GAL4)

CSRE(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YNL111C) OR SimExpr(other) : 8 3

    EXPR: (0.168) mRRPE (P < 0.001) SWI5 (P < 0.000) CSRE (P < 0.000)

ORFSYMBOLPFCTF
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YGR245CSDA1actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation
nucleus ->
nucleus
YDR399WHPT1purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
YOR342CNO SYMBOLRAP1
YNL111CCYB5sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism
electron transporter activity ->
electron transporter activity
microsome ->
membrane fraction
ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
YOR063WRPL3protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
GRF10(Pho2)
YKL181WPRS1histidine biosynthesis, tryptophan biosynthesis, purine salvage, 'de novo' IMP biosynthesis, 'de novo' pyrimidine base biosynthesis ->
amine metabolism, nucleotide biosynthesis, purine ribonucleotide metabolism, aromatic compound metabolism, amino acid derivative biosynthesis, biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, amino acid and derivative metabolism, organic acid metabolism, heterocycle metabolism
ribose-phosphate pyrophosphokinase activity ->
carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups
|YHR213W|NO SYMBOLPHD1
|YAR062W|NO SYMBOL
|YKL093W|MBR1aerobic respiration ->
energy pathways
Main:biosynthesis (0.50)transferase activity\, transferring phosphorus-containing groups (0.40)nucleus (0.60)ABF1 ROX1 (0.33)
Score:0.500.100.400.133
P-value:1.633E-02 (purine nucleotide biosynthesis)1.189E+00 (transferase activity\, transferring phosphorus-containing groups)5.013E-01 (nucleolus)3.026E-01 (ROX1)

CSRE(1) AND ALPHA1'(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YNL111C) OR SimExpr(other) : 6 2

    EXPR: (0.161) ALPHA1' (P < 0.000) mRRPE (P < 0.000) SWI5 (P < 0.000) CSRE (P < 0.000)

ORFSYMBOLPFCTF
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YGR245CSDA1actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation
nucleus ->
nucleus
YNL111CCYB5sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism
electron transporter activity ->
electron transporter activity
microsome ->
membrane fraction
ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
YOR063WRPL3protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
GRF10(Pho2)
YKL181WPRS1histidine biosynthesis, tryptophan biosynthesis, purine salvage, 'de novo' IMP biosynthesis, 'de novo' pyrimidine base biosynthesis ->
amine metabolism, nucleotide biosynthesis, purine ribonucleotide metabolism, aromatic compound metabolism, amino acid derivative biosynthesis, biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, amino acid and derivative metabolism, organic acid metabolism, heterocycle metabolism
ribose-phosphate pyrophosphokinase activity ->
carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups
|YHR213W|NO SYMBOLPHD1
|YAR062W|NO SYMBOL
Main:cell organization and biogenesis (0.50)transferase activity\, transferring phosphorus-containing groups (0.50)nucleus (0.60)ABF1 ROX1 (0.40)
Score:0.600.170.400.200
P-value:4.354E-01 (transcription from Pol I promoter)7.124E-01 (transferase activity\, transferring phosphorus-containing groups)2.761E-01 (nucleolus)1.467E-01 (ROX1)

REB1(1) AND PAC(1) => SimExpr(YNL308C) OR SimExpr(other) : 5 2

SFF'(1) AND STE12(1) AND PAC(1) => SimExpr(YNL308C) OR SimExpr(other) : 5 1

    EXPR: (0.179) SFF' (P < 0.000) STE12 (P < 0.001) PAC (P < 0.183)

ORFSYMBOLPFCTF
YGR158CMTR335S primary transcript processing, mRNA catabolism ->
ribosome biogenesis, mRNA catabolism, RNA processing, transcription from Pol I promoter
3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding
nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus
ZMS1
|YKL142W|MRP8protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex
ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YGR251WNO SYMBOLMSN4, PHD1, SKN7
YJL069CUTP18ABF1
YPR137WRRP9rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, HIR1, RCS1
YNL308CKRI1ribosome biogenesis ->
ribosome biogenesis
nucleolus ->
nucleus
Main:ribosome biogenesis (0.75)RNA binding (0.67)nucleus (0.75)ABF1 SKN7 (0.40)
Score:0.500.330.830.200
P-value:2.288E-02 (ribosome biogenesis)3.804E-01 (RNA binding)1.782E-01 (nucleolus)2.309E-01 (SKN7)

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YNL308C) : 5

    EXPR: (0.142) mRRPE (P < 0.002) STE12 (P < 0.000) PAC (P < 0.012)

ORFSYMBOLPFCTF
YBR247CENP1processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
snoRNA binding
nucleolus, nucleus ->
nucleolus, nucleus
YMR310CNO SYMBOL
YAL059WECM1cell wall organization and biogenesis ->
cell growth and/or maintenance
MOT3
YJL069CUTP18ABF1
YNL308CKRI1ribosome biogenesis ->
cell growth and/or maintenance
nucleolus ->
nucleolus
Main:cell growth and/or maintenance (1.00)snoRNA binding (1.00)nucleolus (1.00)ABF1 (0.50)
Score:1.000.001.000.000
P-value:1.424E-01 (ribosome biogenesis)0.000E+009.149E-02 (nucleolus)1.419E-01 (MOT3)

REB1(1) AND PAC(1) => SimExpr(YPL266W) OR SimExpr(other) : 5 2

REB1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YGR012W) OR SimExpr(other) : 9 4

    EXPR: (0.191) REB1 (P < 0.033) MCM1' (P < 0.001) ALPHA1 (P < 0.002)

ORFSYMBOLPFCTF
YLR455WNO SYMBOL
YMR121CRPL15Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
REB1
YOL148CSPT20chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
protein binding ->
protein binding
SAGA complex ->
nucleus
GRF10(Pho2), MATa1, MIG1, PHO4
YKR048CNAP1nucleosome assembly, M phase of mitotic cell cycle ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation
protein binding ->
protein binding
nucleus ->
nucleus
SKN7
YDR073WSNF11chromatin modeling ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
general RNA polymerase II transcription factor activity ->
general RNA polymerase II transcription factor activity
nucleosome remodeling complex, SWI/SNF complex ->
nucleus
DAL81, RLM1
YOR152CNO SYMBOLHIR2
|YGR147C|NAT2N-terminal peptidyl-methionine acetylation ->
protein metabolism, protein modification
peptide alpha-N-acetyltransferase activity ->
peptide alpha-N-acetyltransferase activity
cytoplasm ->
cytoplasm
HIR1, REB1
|YGL097W|SRM1rRNA-nucleus export, ribosome nucleus export ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, transport
signal transducer activity ->
signal transducer activity
nucleus ->
nucleus
YIL112WHOS4negative regulation of meiosis, histone deacetylation ->
cell proliferation, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity ->
NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity
histone deacetylase complex ->
nucleus
MAC1, REB1, YFL044C
|YKR011C|NO SYMBOLSWI4, SWI6
YGL237CHAP2transcription, regulation of carbohydrate metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism, energy pathways, regulation of metabolism
transcriptional activator activity ->
transcriptional activator activity
nucleus, CCAAT-binding factor complex ->
nucleus
REB1
|YDL232W|OST4N-linked glycosylation ->
biosynthesis, protein metabolism
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding
endoplasmic reticulum membrane ->
cytoplasm, endomembrane system
REB1
YGR012WNO SYMBOLMIG1, REB1
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67)protein binding (0.33)nucleus (0.67)REB1 (0.55)
Score:0.750.080.500.291
P-value:1.495E-02 (DNA packaging)2.960E-01 (protein binding)4.345E-02 (transcription factor complex)5.257E-05 (REB1)

REB1(1) AND ALPHA1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YGR012W) OR SimExpr(other) : 7 3

    EXPR: (0.184) ALPHA1' (P < 0.002) REB1 (P < 0.026) MCM1' (P < 0.001) ALPHA1 (P < 0.001)

ORFSYMBOLPFCTF
YLR455WNO SYMBOL
YMR121CRPL15Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
REB1
YOL148CSPT20chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
protein binding ->
protein binding
SAGA complex ->
nucleus
GRF10(Pho2), MATa1, MIG1, PHO4
YKR048CNAP1nucleosome assembly, M phase of mitotic cell cycle ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation
protein binding ->
protein binding
nucleus ->
nucleus
SKN7
YDR073WSNF11chromatin modeling ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
general RNA polymerase II transcription factor activity ->
general RNA polymerase II transcription factor activity
nucleosome remodeling complex, SWI/SNF complex ->
nucleus
DAL81, RLM1
|YGR147C|NAT2N-terminal peptidyl-methionine acetylation ->
protein metabolism, protein modification
peptide alpha-N-acetyltransferase activity ->
peptide alpha-N-acetyltransferase activity
cytoplasm ->
cytoplasm
HIR1, REB1
YIL112WHOS4negative regulation of meiosis, histone deacetylation ->
cell proliferation, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity ->
NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity
histone deacetylase complex ->
nucleus
MAC1, REB1, YFL044C
|YKR011C|NO SYMBOLSWI4, SWI6
|YDL232W|OST4N-linked glycosylation ->
biosynthesis, protein metabolism
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding
endoplasmic reticulum membrane ->
cytoplasm, endomembrane system
REB1
YGR012WNO SYMBOLMIG1, REB1
Main:protein metabolism (0.71)protein binding (0.43)nucleus (0.57)REB1 (0.56)
Score:0.710.140.430.306
P-value:4.728E-03 (DNA packaging)1.219E-01 (protein binding)2.066E-01 (nucleoplasm)2.104E-04 (REB1)

REB1(1) AND PAC(1) => SimExpr(YOR021C) OR SimExpr(other) : 5 2

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR272W) OR SimExpr(other) : 38 3

    EXPR: (0.154) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000)

ORFSYMBOLPFCTF
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
|YDR279W|RNH202GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YNL292WPUS4tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
pseudouridylate synthase activity ->
carbon-oxygen lyase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
|YOR381W|FRE3iron-siderochrome transport, iron ion homeostasis ->
cell growth and/or maintenance
ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions
plasma membrane, integral to membrane ->
plasma membrane, integral to membrane
CIN5, PDR1, YAP6
YNL112WDBP2RNA helicase activity ->
RNA binding
bud neck ->
site of polarized growth (sensu Fungi)
YDR184CATC1response to stress, polar budding ->
response to stress, asexual reproduction
nucleus ->
nucleus
ARO80, GLN3, SIP4, SKO1
YGR245CSDA1actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell growth and/or maintenance
nucleus ->
nucleus
YOR078WBUD21processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, MSS11, SIG1, SKO1
YMR229CRRP5rRNA processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding, snoRNA binding ->
RNA binding
nucleolus, nucleolus organizer complex ->
nucleus
FHL1, RAP1
YKL014CNO SYMBOLABF1
YFR001WLOC1ribosomal large subunit biogenesis ->
cell growth and/or maintenance
mRNA binding ->
RNA binding
nucleus ->
nucleus
ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
YHR196WUTP9processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YLR276CDBP9ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
MATa1, RCS1, RTG3, SWI5
YML093WUTP14processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YJL109CUTP10processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YJL033WHCA435S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
HIR2, USV1
YNL075WIMP4rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
rRNA primary transcript binding ->
RNA binding
small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
USV1
YNL175CNOP13RNA binding ->
RNA binding
nucleolus, nucleoplasm ->
nucleus
INO2, INO4
YMR049CERB1rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RTG3
YOR095CRKI1pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism
ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity
FHL1, FKH2, RAP1
YOR359WVTS1protein-vacuolar targeting ->
protein metabolism, cell growth and/or maintenance
intracellular transporter activity ->
intracellular transporter activity
cytosol ->
cytoplasm
RAP1
YNL132WKRE33
YHR169WDBP835S primary transcript processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
YOR272WYTM1chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis ->
cell growth and/or maintenance
nucleus, nucleolus ->
nucleus
LEU3, PUT3, REB1
YGL029WCGR1ribosome biogenesis, rRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleolus ->
nucleus
YNR024WNO SYMBOL
YNR053CNOG2mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleus, nucleolus, nucleoplasm ->
nucleus, nucleoplasm
ABF1, AZF1
YGR162WTIF4631translational initiation ->
biosynthesis, protein metabolism
translation initiation factor activity ->
translation factor activity\, nucleic acid binding
ribosome ->
cytoplasm, ribonucleoprotein complex
HSF1
YGL169WSUA5cell growth and/or maintenance ->
cell growth and/or maintenance
ABF1
YGL099WLSG1conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, protein metabolism, cell growth and/or maintenance, sexual reproduction
GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
cytoplasm ->
cytoplasm
PHO4
YDR496CPUF6RFX1
YJR070CNO SYMBOLGAT3, YAP5
YLR222CUTP13processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1
YGR280CPXR135S primary transcript processing, snRNA processing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YAL059WECM1cell wall organization and biogenesis ->
cell growth and/or maintenance
MOT3
|YPR183W|DPM1N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system
SWI5
YGL171WROK135S primary transcript processing, mRNA splicing ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity, ATPase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
RGT1
YDR449CUTP6processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YOL022CNO SYMBOLMAC1, MOT3, RTS2
YNL308CKRI1ribosome biogenesis ->
cell growth and/or maintenance
nucleolus ->
nucleus
Main:cell growth and/or maintenance (0.78)RNA binding (0.64)nucleus (0.80)ABF1 (0.20)
Score:0.720.430.680.080
P-value:6.573E-17 (ribosome biogenesis)1.324E-08 (snoRNA binding)8.040E-18 (nucleolus)1.000E+00

REB1(1) AND PAC(1) => SimExpr(YOR272W) OR SimExpr(other) : 5 2

CSRE(1) AND SWI5(1) AND PAC(1) => SimExpr(YPR010C) OR SimExpr(other) : 5 1

    EXPR: (0.128) SWI5 (P < 0.000) PAC (P < 0.004) CSRE (P < 0.000)

ORFSYMBOLPFCTF
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
YGR245CSDA1actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation
nucleus ->
nucleus
|YKL120W|OAC1oxaloacetate transport, sulfate transport ->
transport
oxaloacetate carrier activity, sulfate porter activity ->
oxaloacetate carrier activity, sulfate porter activity
mitochondrial inner membrane ->
cytoplasm, inner membrane
LEU3, MTH1
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YDR399WHPT1purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
YPL143WRPL33Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MET4, NDD1, PDR1, RAP1, RME1
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.50)oxaloacetate carrier activity (0.25)nucleus (0.60)ABF1 (0.25)
Score:0.330.000.500.000
P-value:2.269E-01 (transcription from Pol I promoter)9.575E-01 (transferase activity)1.782E-01 (nucleolus)7.609E-01 (LEU3)

ABF1(1) AND PAC(1) => SimExpr(YPR010C) OR SimExpr(other) : 12 3

    EXPR: (0.153) ABF1 (P < 0.000) PAC (P < 0.004)

ORFSYMBOLPFCTF
YGR283CNO SYMBOLACE2, RAP1, SMP1
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
YNL292WPUS4tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
pseudouridylate synthase activity ->
carbon-oxygen lyase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
YNL112WDBP2RNA helicase activity ->
RNA binding
bud neck ->
site of polarized growth (sensu Fungi)
YKL014CNO SYMBOLABF1
YKL172WEBP2rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleolus ->
nucleus
ABF1, FZF1, RFX1
YLR197WSIK1rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex
DAL81, HAL9
YGR187CHGH1ABF1, HAP3, HIR1, RCS1, RTG1
YKL078WDHR2ribosome biogenesis ->
cell organization and biogenesis
RNA helicase activity ->
RNA binding
nucleolus ->
nucleus
ABF1
YOL041CNOP12rRNA metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
GTS1, MET31
|YHR027C|RPN1ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity, receptor activity ->
peptidase activity, receptor activity
proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YJL050WMTR435S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
|YJL069C|UTP18ABF1
YNR046WNO SYMBOLABF1
|YDR527W|NO SYMBOLABF1, SKN7
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.75)RNA binding (0.57)nucleus (0.89)ABF1 (0.58)
Score:0.640.290.780.333
P-value:3.084E-02 (transcription from Pol I promoter)4.360E-03 (RNA helicase activity)9.555E-05 (nucleolus)4.241E-04 (ABF1)

CSRE(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YPR010C) OR SimExpr(other) : 8 3

ABF1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YPR010C) : 5

    EXPR: (0.123) ABF1 (P < 0.000) ALPHA1' (P < 0.000) PAC (P < 0.017)

ORFSYMBOLPFCTF
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
YNL292WPUS4tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
pseudouridylate synthase activity ->
carbon-oxygen lyase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
YNL112WDBP2RNA helicase activity ->
RNA binding
bud neck ->
site of polarized growth (sensu Fungi)
YKL014CNO SYMBOLABF1
YOL041CNOP12rRNA metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
GTS1, MET31
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00)RNA binding (0.50)nucleus (0.75)ABF1 (0.25)
Score:1.000.170.500.000
P-value:2.945E-01 (RNA metabolism)3.207E-01 (RNA binding)9.149E-02 (nucleolus)3.426E-01 (SIG1)

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YPR010C) : 5

    EXPR: (0.093) mRRPE (P < 0.000) PAC (P < 0.001) CSRE (P < 0.000)

ORFSYMBOLPFCTF
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
YGR245CSDA1actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation
nucleus ->
nucleus
YGR159CNSR1ribosomal small subunit assembly and maintenance, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
single-stranded DNA binding, RNA binding ->
single-stranded DNA binding, RNA binding
nucleolus, nucleus ->
nucleus
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YDR399WHPT1purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.80)RNA binding (0.33)nucleus (1.00)ABF1 (0.50)
Score:0.800.001.000.000
P-value:7.183E-03 (transcription from Pol I promoter)7.087E-01 (transferase activity)3.698E-03 (nucleolus)2.284E-01 (SIG1)

mRRPE(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 56 20

CSRE(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YOR310C) OR SimExpr(other) : 8 3

mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 11 5

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 16 4

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 30 11

CSRE(1) AND SWI5(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 5 1

SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 9 2

    EXPR: (0.131) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001) SCB (P < 0.000)

ORFSYMBOLPFCTF
YHR052WCIC1protein catabolism ->
macromolecule catabolism, protein metabolism
protein binding\, bridging ->
protein binding\, bridging
nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm
HAP4, MATa1
|YNL292W|PUS4tRNA modification ->
RNA metabolism
pseudouridylate synthase activity ->
carbon-oxygen lyase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
YJL138CTIF2translational initiation, regulation of translational initiation ->
macromolecule biosynthesis, protein metabolism
translation initiation factor activity, RNA helicase activity ->
translation factor activity\, nucleic acid binding, RNA binding
ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex
PHD1
YNL112WDBP2RNA helicase activity ->
RNA binding
bud neck ->
site of polarized growth (sensu Fungi)
YOR078WBUD21processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, MSS11, SIG1, SKO1
YJL109CUTP10processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YLR249WYEF3translational elongation ->
macromolecule biosynthesis, protein metabolism
translation elongation factor activity ->
translation factor activity\, nucleic acid binding
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YKL056CNO SYMBOL
YGR280CPXR135S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription
RNA binding ->
RNA binding
nucleolus ->
nucleus
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription\, DNA-dependent
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
|YJL069C|UTP18ABF1
Main:RNA metabolism (0.62)RNA binding (0.62)nucleus (0.67)ABF1 (0.43)
Score:0.460.390.720.143
P-value:2.618E-03 (processing of 20S pre-rRNA)1.000E-02 (RNA binding)3.708E-04 (nucleolus)3.796E-01 (ABF1)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 7 1

    EXPR: (0.131) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001) SCB (P < 0.000)

ORFSYMBOLPFCTF
|YNL292W|PUS4tRNA modification ->
RNA processing, tRNA metabolism
pseudouridylate synthase activity ->
carbon-oxygen lyase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
YNL112WDBP2RNA helicase activity ->
RNA binding
bud neck ->
site of polarized growth (sensu Fungi)
YDR184CATC1response to stress, polar budding ->
response to stress, polar budding
nucleus ->
nucleus
ARO80, GLN3, SIP4, SKO1
YOR078WBUD21processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, MSS11, SIG1, SKO1
YJL109CUTP10processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YJR070CNO SYMBOLGAT3, YAP5
YGR280CPXR135S primary transcript processing, snRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
RNA binding ->
RNA binding
nucleolus ->
nucleus
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
Main:RNA processing (0.83)RNA binding (0.80)nucleus (0.86)ABF1 SKO1 (0.40)
Score:0.670.600.710.200
P-value:7.533E-04 (processing of 20S pre-rRNA)7.782E-03 (snoRNA binding)2.268E-04 (small nucleolar ribonucleoprotein complex)2.853E-02 (SKO1)

ALPHA1'(1) AND mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 8 2

    EXPR: (0.154) ALPHA1' (P < 0.000) mRRPE (P < 0.002) SWI5 (P < 0.000) PAC (P < 0.013)

ORFSYMBOLPFCTF
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
|YDR279W|RNH202GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YGR245CSDA1actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation
nucleus ->
nucleus
YMR229CRRP5rRNA processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding, snoRNA binding ->
RNA binding
nucleolus, nucleolus organizer complex ->
nucleus
FHL1, RAP1
YFR001WLOC1ribosomal large subunit biogenesis ->
cell organization and biogenesis
mRNA binding ->
RNA binding
nucleus ->
nucleus
ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
YJL109CUTP10processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YNR024WNO SYMBOL
YGR280CPXR135S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
|YPR183W|DPM1N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system
SWI5
Main:cell organization and biogenesis (0.75)RNA binding (0.67)nucleus (0.88)RLM1 SWI6 (0.33)
Score:0.680.400.750.133
P-value:2.132E-04 (transcription from Pol I promoter)1.419E-02 (snoRNA binding)1.670E-04 (nucleolus)4.867E-01 (RLM1)

mRRPE(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 5 1

    EXPR: (0.117) mRRPE (P < 0.000) SWI5 (P < 0.000) PAC (P < 0.001) SCB (P < 0.000)

ORFSYMBOLPFCTF
|YMR259C|NO SYMBOLARG80, GCR2, GTS1, HIR1, SRD1
YJL109CUTP10processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation factor activity\, nucleic acid binding
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YGR280CPXR135S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
YOR310CNOP58rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1, SWI6
YDR399WHPT1purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.80)RNA binding (0.50)nucleus (0.75)ABF1 (0.33)
Score:0.700.170.830.000
P-value:9.864E-03 (rRNA processing)3.308E-01 (nucleic acid binding)8.330E-03 (small nucleolar ribonucleoprotein complex)7.610E-01 (SRD1)

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR310C) : 5

CSRE(1) AND ALPHA1'(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YOR063W) OR SimExpr(other) : 6 2

ABF1(1) AND RPN4(1) => SimExpr(YGR253C) OR SimExpr(other) : 6 1

    EXPR: (0.152) ABF1 (P < 0.000) RPN4 (P < 0.047)

ORFSYMBOLPFCTF
YFR020WNO SYMBOLMIG1
|YNL251C|NRD1nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleus ->
nucleus
ABF1, MAC1
YJR006WHYS2leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA repair, cell proliferation
delta DNA polymerase activity ->
delta DNA polymerase activity
delta DNA polymerase complex ->
cytoplasm, nucleus
ABF1
YHR027CRPN1ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity, receptor activity ->
endopeptidase activity, receptor activity
proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YGR253CPUP2ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) ->
catabolism, response to stress, sporulation, protein metabolism
endopeptidase activity ->
endopeptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
ABF1, HIR2, PHO4
YHL024WRIM4sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination ->
sporulation, M phase, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation
RNA binding ->
RNA binding
cytoplasm ->
cytoplasm
FKH2, PHD1
YOR362CPRE10ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
endopeptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.50)endopeptidase activity (0.50)cytoplasm (0.83)ABF1 (0.60)
Score:0.470.270.930.300
P-value:1.746E-02 (ubiquitin-dependent protein catabolism)7.474E-04 (endopeptidase activity)6.518E-04 (proteasome complex (sensu Eukarya))6.278E-02 (ABF1)

CSRE(1) AND SWI5(1) AND PAC(1) => SimExpr(YDR399W) OR SimExpr(other) : 5 1

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YDR399W) : 5

ALPHA2(1) AND ABF1(1) => SimExpr(YGL207W) OR SimExpr(other) : 9 4

    EXPR: (0.190) ALPHA2 (P < 0.006) ABF1 (P < 0.075)

ORFSYMBOLPFCTF
YDL195WSEC31ER to Golgi transport ->
transport, vesicle-mediated transport
structural molecule activity ->
structural molecule activity
COPII vesicle coat ->
cytoplasm
ABF1, GAT1, MTH1, SFL1, SIG1
YLR429WCRN1actin filament organization, microtubule-based process ->
cell organization and biogenesis
actin cross-linking activity, microtubule binding ->
actin cross-linking activity, microtubule binding
actin cortical patch (sensu Saccharomyces) ->
cell cortex, cytoplasm
|YJL097W|NO SYMBOLARG80, HAP3
|YNL111C|CYB5sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism
electron transporter activity ->
electron transporter activity
microsome ->
membrane fraction
ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YKR046CPET10lipid particle ->
cytoplasm
ABF1
YGL207WSPT16chromatin modeling, regulation of global transcription from Pol II promoter, RNA elongation from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA metabolism
transcriptional elongation regulator activity ->
transcriptional elongation regulator activity
alpha DNA polymerase\:primase complex, nuclear chromatin, transcription elongation factor complex ->
nucleus, chromosome
RTG1
|YKL172W|EBP2rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleolus ->
nucleus
ABF1, FZF1, RFX1
YAL016WTPD3protein biosynthesis, actin filament organization, mitotic spindle checkpoint, bud growth, protein amino acid dephosphorylation ->
biosynthesis, cell organization and biogenesis, asexual reproduction, phosphorus metabolism, cell proliferation, cell cycle, protein metabolism
protein phosphatase type 2A activity ->
protein phosphatase type 2A activity
protein phosphatase type 2A complex, bud neck, nucleus, cytoplasm, shmoo tip, bud tip, spindle pole body ->
protein phosphatase type 2A complex, nucleus, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), cytoplasm, microtubule organizing center
ABF1
YJL091CGWT1GPI anchor biosynthesis ->
biosynthesis, membrane lipid metabolism, protein metabolism, lipid metabolism
membrane ->
membrane
YHR027CRPN1ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity, receptor activity ->
endopeptidase activity, receptor activity
proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YKR084CHBS1protein biosynthesis ->
biosynthesis, protein metabolism
PHO4
|YNR046W|NO SYMBOLABF1
YNL059CARP5protein-vacuolar targeting ->
cell organization and biogenesis, protein metabolism, transport
nucleus ->
nucleus
ABF1, GRF10(Pho2)
Main:cell organization and biogenesis (0.50)electron transporter activity (0.17)cytoplasm (0.50)ABF1 (0.70)
Score:0.510.000.420.467
P-value:3.890E-01 (actin filament organization)2.991E+00 (hydrolase activity)1.171E+00 (cytoskeleton)1.272E-04 (ABF1)

SFF(1) AND MCB(1) AND ATRepeat(1) => SimExpr(YJR006W) OR SimExpr(other) : 6 2

    EXPR: (0.171) SFF (P < 0.000) MCB (P < 0.030) ATRepeat (P < 0.005)

ORFSYMBOLPFCTF
YDL003WMCD1mitotic sister chromatid cohesion, mitotic chromosome condensation ->
cell proliferation, cell cycle
nuclear cohesin complex ->
chromosome, nucleus
CIN5, MBP1, SWI6
YPR185WAPG13protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport
protein binding ->
protein binding
extrinsic to membrane ->
extrinsic to membrane
MET4, SWI6
YLR212CTUB4microtubule nucleation, mitotic spindle assembly (sensu Saccharomyces) ->
cell organization and biogenesis, cell proliferation, cell cycle
structural constituent of cytoskeleton ->
structural constituent of cytoskeleton
inner plaque of spindle pole body, outer plaque of spindle pole body ->
cytoplasm
YPL123CRNY1cellular morphogenesis ->
cell organization and biogenesis
endoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding
extracellular ->
extracellular
ARG80, CUP9, DAL81, FZF1, NRG1, STB1
YJR006WHYS2leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA repair, cell proliferation
delta DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
delta DNA polymerase complex ->
cytoplasm, nucleus
ABF1
|YNL102W|POL1DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis ->
DNA metabolism, cell proliferation
alpha DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
alpha DNA polymerase\:primase complex ->
nucleus
LEU3, MBP1
YLR430WSEN135S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
ARG80, GTS1, HAP5, RTG3, SIP4
|YMR102C|NO SYMBOL
Main:cell organization and biogenesis (0.57)RNA binding (0.33)nucleus (0.57)ARG80 MBP1 SWI6 (0.33)
Score:0.620.130.330.200
P-value:3.346E-03 (lagging strand elongation)1.223E-02 (DNA-directed DNA polymerase activity)1.056E-02 (replication fork)1.376E-01 (ARG80)

CSRE(1) AND PHO4(1) => SimExpr(YOR299W) OR SimExpr(other) : 5 1

mRRPE(1) AND PAC(1) => SimExpr(YGR159C) OR SimExpr(other) : 52 24

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR159C) : 5

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR245C) : 5

CSRE(1) AND OAF1(1) => SimExpr(YJR019C) OR SimExpr(other) : 5 1

    EXPR: (0.153) OAF1 (P < 0.010) CSRE (P < 0.001)

ORFSYMBOLPFCTF
YJR019CTES1fatty acid oxidation ->
lipid metabolism, carboxylic acid metabolism
acyl-CoA thioesterase activity ->
acyl-CoA thioesterase activity
peroxisome ->
cytoplasm
DAL82, MTH1
YLR174WIDP2isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism
isocitrate dehydrogenase (NADP+) activity ->
isocitrate dehydrogenase (NADP+) activity
cytosol ->
cytoplasm
ABF1, CBF1, RAP1
YMR135CGID8negative regulation of gluconeogenesis ->
alcohol biosynthesis, regulation of biosynthesis, monosaccharide metabolism, carbohydrate metabolism, negative regulation of metabolism, carbohydrate biosynthesis, energy derivation by oxidation of organic compounds, regulation of metabolism
ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
|YDR134C|NO SYMBOLASH1, NRG1, SOK2, SWI4
YNL329CPEX6peroxisome organization and biogenesis ->
cytoplasm organization and biogenesis
ATPase activity ->
ATPase activity
peroxisome ->
cytoplasm
RAP1
YML042WCAT2carnitine metabolism ->
amine metabolism, carboxylic acid metabolism, water-soluble vitamin metabolism, amino acid derivative metabolism
carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity
peroxisomal matrix, mitochondrion, peroxisome ->
cytoplasm
MAL13
Main:carboxylic acid metabolism (0.60)ATPase activity (0.25)cytoplasm (1.00)SWI4 RAP1 ASH1 NRG1 (0.33)
Score:0.400.001.000.133
P-value:4.936E-02 (organic acid metabolism)1.308E+00 (hydrolase activity)2.629E-04 (peroxisome)2.324E-02 (ASH1)

RAP1(1) AND SCB(1) => SimExpr(YLR344W) OR SimExpr(other) : 10 2

    EXPR: (0.145) SCB (P < 0.000) RAP1 (P < 0.093)

ORFSYMBOLPFCTF
YMR194WRPL36Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
|YOL160W|NO SYMBOLARO80, NRG1, PHO4, RLM1, SIP4, SWI6
YNL024CNO SYMBOLGRF10(Pho2)
YGR085CRPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MIG1
|YPL189W|GUP2membrane ->
membrane
RFX1
YPL131WRPL5protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1
YLR344WRPL26Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, RAP1
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YGR260WTNA1nicotinamide mononucleotide transport ->
transport
nicotinamide mononucleotide permease activity ->
nicotinamide mononucleotide permease activity
integral to plasma membrane ->
membrane
HIR2, SUM1
YPR080WTEF1translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
FHL1, PDR1, RAP1, YAP5
YOR369CRPS12protein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YLR208WSEC13nonselective vesicle assembly, ER to Golgi transport, ER-associated protein catabolism ->
macromolecule catabolism, transport, protein metabolism
cytoplasm, COPII vesicle coat, nuclear pore, extrinsic to plasma membrane ->
nucleus, cytoplasm, membrane coat, membrane
Main:protein metabolism (0.89)structural constituent of ribosome (0.62)cytoplasm (0.80)FHL1 (0.55)
Score:0.810.390.690.291
P-value:2.067E-03 (protein biosynthesis)4.393E-03 (structural constituent of ribosome)1.274E-04 (ribosome)1.492E-05 (FHL1)

RAP1(1) AND MCM1'(1) => SimExpr(YLR344W) OR SimExpr(other) : 16 5

RAP1(1) AND SWI5(1) => SimExpr(YLR344W) OR SimExpr(other) : 16 7

    EXPR: (0.164) SWI5 (P < 0.000) RAP1 (P < 0.395)

ORFSYMBOLPFCTF
|YOR213C|SAS5chromatin silencing at telomere ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
acetyltransferase activity ->
transferase activity\, transferring groups other than amino-acyl groups
nuclear chromosome\, telomeric region, nuclear chromatin ->
chromosome, nuclear chromosome
GRF10(Pho2), SUM1
YMR194WRPL36Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
|YMR013C|SEC59protein-ER targeting, protein amino acid glycosylation ->
cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport
dolichol kinase activity ->
phosphotransferase activity\, alcohol group as acceptor
membrane ->
membrane
FHL1, NDD1, RAP1, RLM1, RME1
YKR092CSRP40nucleocytoplasmic transport ->
transport
chaperone activity ->
chaperone activity
nucleolus ->
nucleus
CUP9, MET4, RAP1
YLR441CRPS1Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, YAP5
YMR224CMRE11DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication ->
DNA metabolism, cell proliferation, catabolism
endonuclease activity, 3'-5' exonuclease activity, protein binding ->
nuclease activity, protein binding
nucleus ->
nucleus
RAP1
YDR450WRPS18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
|YGL196W|NO SYMBOL
YGL030WRPL30protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation ->
cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, SFP1
|YNL311C|NO SYMBOLGCN4, RAP1
YNL069CRPL16Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YLR344WRPL26Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, RAP1
YOR312CRPL20Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, FKH2, GAT3, RAP1
YJR145CRPS4Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
|YGL115W|SNF4regulation of transcription from Pol II promoter, peroxisome organization and biogenesis ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
protein kinase activator activity ->
protein kinase activator activity
plasma membrane, nucleus, cytoplasm ->
membrane, nucleus, cytoplasm
BAS1, CAD1, MAC1, NRG1, PDR1, RAP1, SMP1, YAP5
|YJL217W|NO SYMBOLCIN5, MAC1, PHD1, SWI5, YAP6
YOL120CRPL18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MAL13, RAP1, YAP5
YPR080WTEF1translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
FHL1, PDR1, RAP1, YAP5
YLR452CSST2signal transduction, adaptation to pheromone during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus
GTPase activator activity ->
GTPase activator activity
plasma membrane ->
membrane
DIG1, FHL1, RAP1, STE12
YOR369CRPS12protein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
|YPR161C|SGV1transcription, protein amino acid phosphorylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, phosphorus metabolism, protein metabolism
cyclin-dependent protein kinase activity ->
phosphotransferase activity\, alcohol group as acceptor
nucleus ->
nucleus
RAP1
YKL006WRPL14Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
Main:protein metabolism (0.75)structural constituent of ribosome (0.55)cytoplasm (0.70)RAP1 (0.82)
Score:0.590.300.530.745
P-value:3.312E-07 (protein biosynthesis)3.091E-07 (structural constituent of ribosome)1.091E-08 (cytosolic ribosome (sensu Eukarya))5.425E-17 (RAP1)

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YLR344W) : 7

    EXPR: (0.110) SWI5 (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.005)

ORFSYMBOLPFCTF
YDR450WRPS18Aprotein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YGL030WRPL30protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation ->
protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytosolic ribosome (sensu Eukarya), cytoplasm, large ribosomal subunit
FHL1, GAT3, RAP1, SFP1
YNL069CRPL16Bprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YLR344WRPL26Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, RAP1
YOL120CRPL18Aprotein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, MAL13, RAP1, YAP5
YLR452CSST2signal transduction, adaptation to pheromone during conjugation with cellular fusion ->
signal transduction, adaptation to pheromone during conjugation with cellular fusion
GTPase activator activity ->
GTPase activator activity
plasma membrane ->
plasma membrane
DIG1, FHL1, RAP1, STE12
YKL006WRPL14Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
Main:protein biosynthesis (0.86)structural constituent of ribosome (0.86)cytosolic ribosome (sensu Eukarya) (0.86)RAP1 FHL1 (1.00)
Score:0.710.710.711.000
P-value:1.231E-04 (protein biosynthesis)2.118E-06 (structural constituent of ribosome)5.117E-07 (cytosolic ribosome (sensu Eukarya))1.933E-10 (FHL1)

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YLR344W) : 6

    EXPR: (0.117) ALPHA1' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.027)

ORFSYMBOLPFCTF
YMR194WRPL36Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
YNL024CNO SYMBOLGRF10(Pho2)
YPL131WRPL5protein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosome biogenesis and assembly
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1
YLR344WRPL26Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, RAP1
YPR080WTEF1translational elongation ->
protein biosynthesis
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
ribosome
FHL1, PDR1, RAP1, YAP5
YOR369CRPS12protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
Main:protein biosynthesis (1.00)structural constituent of ribosome (0.80)ribosome (1.00)FHL1 (0.83)
Score:1.000.601.000.667
P-value:8.374E-04 (protein biosynthesis)1.274E-03 (structural constituent of ribosome)1.752E-04 (ribosome)2.789E-06 (FHL1)

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR344W) : 5

    EXPR: (0.111) SWI5 (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.015)

ORFSYMBOLPFCTF
YMR194WRPL36Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
YLR344WRPL26Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, RAP1
YLR249WYEF3translational elongation ->
protein biosynthesis
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
ribosome
INO2, INO4
YPR080WTEF1translational elongation ->
protein biosynthesis
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
ribosome
FHL1, PDR1, RAP1, YAP5
YOR369CRPS12protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
Main:protein biosynthesis (1.00)structural constituent of ribosome (0.60)ribosome (1.00)FHL1 (0.80)
Score:1.000.401.000.600
P-value:1.732E-04 (protein biosynthesis)1.679E-03 (translation elongation factor activity)3.116E-05 (ribosome)8.308E-05 (FHL1)

RPN4(1) => SimExpr(YGL201C) OR SimExpr(other) : 35 17

    EXPR: (0.190) RPN4 (P < 0.547)

ORFSYMBOLPFCTF
YFR020WNO SYMBOLMIG1
YGR135WPRE9ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
REB1, SKO1
|YNL251C|NRD1nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleus ->
nucleus
ABF1, MAC1
|YGR184C|UBR1protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism
ubiquitin-protein ligase activity ->
ligase activity\, forming carbon-nitrogen bonds
proteasome complex (sensu Eukarya) ->
cytoplasm, nucleus
HMS1, REB1, RIM101
|YGR286C|BIO2biotin biosynthesis ->
biosynthesis, coenzymes and prosthetic group metabolism, vitamin metabolism, heterocycle metabolism, organic acid metabolism, sulfur metabolism
biotin synthase activity ->
transferase activity\, transferring sulfur-containing groups
YDR427WRPN9ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome regulatory particle (sensu Eukarya), proteasome regulatory particle\, lid subcomplex (sensu Eukarya) ->
cytoplasm, nucleus
ARG81, IXR1
|YJR159W|SOR1fructose metabolism, mannose metabolism ->
alcohol metabolism, carbohydrate metabolism
L-iditol 2-dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors
ASH1, CUP9, MOT3, MTH1, NRG1, PHD1, RLM1, ROX1, SOK2, YAP6
YGR142WBTN2regulation of pH, intracellular protein transport ->
cell homeostasis, transport
cytosol ->
cytoplasm
HSF1, MSN4
YFR050CPRE4ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
MTH1, REB1
|YGR235C|NO SYMBOLREB1
YFR010WUBP6protein deubiquitination ->
catabolism, protein metabolism
ubiquitin-specific protease activity ->
peptidase activity
proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus
ABF1
|YPL190C|NAB3regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
poly(A) binding ->
RNA binding
nucleoplasm ->
nucleus
RFX1
|YJL058C|BIT61
YGL201CMCM6DNA unwinding, DNA replication initiation ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
chromatin binding, ATP dependent DNA helicase activity ->
DNA binding, adenyl nucleotide binding, hydrolase activity\, acting on acid anhydrides
cytoplasm, nucleus, pre-replicative complex ->
cytoplasm, nucleus
MCM1
YOR097CNO SYMBOL
YJR006WHYS2leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA repair, cell proliferation
delta DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
delta DNA polymerase complex ->
cytoplasm, nucleus
ABF1
|YNL012W|SPO1meiosis ->
cell proliferation
phospholipase activity ->
hydrolase activity\, acting on ester bonds
nucleus ->
nucleus
ARO80, SRD1
|YJL045W|NO SYMBOLMBP1, ROX1
YFL044CNO SYMBOL
YIL075CRPN2ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
receptor activity, endopeptidase activity ->
receptor activity, peptidase activity
proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus
MSS11, REB1, SFL1
YMR100WMUB1regulation of budding ->
asexual reproduction
YFL056CAAD6aldehyde metabolism ->
aldehyde metabolism
benzyl alcohol dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors
ACE2, YAP1
YOR007CSGT2
|YJR015W|NO SYMBOL
YML092CPRE8ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
YNL097CPHO23chromatin modification ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleus ->
nucleus
MAC1
YGR124WASN2asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis
asparagine synthase (glutamine-hydrolyzing) activity ->
ligase activity\, forming carbon-nitrogen bonds
ASH1, ROX1
YKL135CAPL2vesicle-mediated transport ->
transport
clathrin binding ->
protein binding
AP-1 adaptor complex ->
cytoplasmic vesicle, cytoplasm
ABF1, DOT6
YGL238WCSE1protein-nucleus export ->
protein metabolism, transport
importin-alpha export receptor activity ->
protein binding
nuclear membrane ->
nucleus, endomembrane system
REB1
|YGL096W|TOS8transcription factor activity ->
DNA binding
IXR1, SOK2, SWI4
YGL062WPYC1NADPH regeneration, gluconeogenesis ->
coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways
pyruvate carboxylase activity ->
ligase activity\, forming carbon-carbon bonds
cytosol ->
cytoplasm
DIG1, GCR1, STE12
|YKL203C|TOR2cytoskeleton organization and biogenesis, ribosome biogenesis, signal transduction, Rho protein signal transduction, regulation of cell cycle, G1 phase of mitotic cell cycle, cell cycle dependent actin filament reorganization ->
cell organization and biogenesis, signal transduction, cell cycle, cytoplasm organization and biogenesis
phosphatidylinositol 3-kinase activity, protein binding ->
transferase activity\, transferring phosphorus-containing groups, protein binding, lipid kinase activity
vacuolar membrane, plasma membrane ->
cytoplasm, plasma membrane
BAS1, HIR1, REB1, RTG1
YOL131WNO SYMBOL
YGL122CNAB2poly(A)+ mRNA-nucleus export, mRNA polyadenylation ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
poly(A) binding ->
RNA binding
nucleus, cytoplasm ->
nucleus, cytoplasm
ABF1
YOL038WPRE6ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
|YNL241C|ZWF1pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism
glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors
cytoplasm ->
cytoplasm
ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
|YGR060W|ERG25ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism
C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity
endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system
HSF1, MAL13, MET4, NDD1, SWI5
YJL116CNCA3mitochondrion organization and biogenesis ->
cell organization and biogenesis
CBF1, MBP1, SKN7, SWI6
YKL145WRPT1ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
ATPase activity, endopeptidase activity ->
purine nucleotide binding, peptidase activity, hydrolase activity\, acting on acid anhydrides
proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus
REB1
YHR027CRPN1ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity, receptor activity ->
peptidase activity, receptor activity
proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YGR253CPUP2ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) ->
catabolism, response to stress, sporulation, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
ABF1, HIR2, PHO4
YOR052CNO SYMBOL
|YHL024W|RIM4sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination ->
sporulation, M phase, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation
RNA binding ->
RNA binding
cytoplasm ->
cytoplasm
FKH2, PHD1
YKL210WUBA1ubiquitin cycle ->
catabolism, protein metabolism
ubiquitin activating enzyme activity ->
ubiquitin activating enzyme activity
nucleus, cytoplasm ->
nucleus, cytoplasm
SKO1
YDL126CCDC48ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism ->
cell proliferation, cell death, macromolecule catabolism, transport, protein metabolism
ATPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleus, microsome, endoplasmic reticulum, cytosol ->
nucleus, membrane fraction, cytoplasm
DAL82, MAL33, SWI4
YKL054CDEF1response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism
nucleus ->
nucleus
YER021WRPN3ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus
YJR090CGRR1ubiquitin-dependent protein catabolism, G1/S transition of mitotic cell cycle ->
catabolism, cell proliferation, protein metabolism
ubiquitin-protein ligase activity, protein binding ->
ligase activity\, forming carbon-nitrogen bonds, protein binding
nuclear ubiquitin ligase complex, nucleus, cytoplasm, contractile ring (sensu Saccharomyces) ->
nucleus, site of polarized growth (sensu Fungi), cell cortex, cytoplasm, ubiquitin ligase complex
REB1
YDL007WRPT2ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
ATPase activity, endopeptidase activity ->
purine nucleotide binding, peptidase activity, hydrolase activity\, acting on acid anhydrides
proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus
REB1
YOR362CPRE10ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
|YKL160W|ELF1cell growth ->
cell growth
|YOR339C|UBC11protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism
ubiquitin conjugating enzyme activity ->
ubiquitin conjugating enzyme activity
cytoplasm ->
cytoplasm
HAP2, IXR1
Main:protein metabolism (0.49)peptidase activity (0.36)cytoplasm (0.82)REB1 (0.28)
Score:0.320.160.920.129
P-value:4.128E-16 (ubiquitin-dependent protein catabolism)4.363E-12 (endopeptidase activity)8.639E-17 (proteasome complex (sensu Eukarya))9.749E-04 (REB1)

ALPHA1(1) AND RPN4(1) => SimExpr(YGL201C) OR SimExpr(other) : 13 6

    EXPR: (0.188) RPN4 (P < 0.477) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
YGR135WPRE9ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
REB1, SKO1
|YNL251C|NRD1nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleus ->
nucleus
ABF1, MAC1
|YGR184C|UBR1protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism
ubiquitin-protein ligase activity ->
ligase activity\, forming carbon-nitrogen bonds
proteasome complex (sensu Eukarya) ->
cytoplasm, nucleus
HMS1, REB1, RIM101
YFR050CPRE4ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
MTH1, REB1
YGL201CMCM6DNA unwinding, DNA replication initiation ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
chromatin binding, ATP dependent DNA helicase activity ->
DNA binding, adenyl nucleotide binding, hydrolase activity\, acting on acid anhydrides
cytoplasm, nucleus, pre-replicative complex ->
cytoplasm, nucleus
MCM1
|YJR015W|NO SYMBOL
YNL097CPHO23chromatin modification ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleus ->
nucleus
MAC1
YGR124WASN2asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis
asparagine synthase (glutamine-hydrolyzing) activity ->
ligase activity\, forming carbon-nitrogen bonds
ASH1, ROX1
|YGL096W|TOS8transcription factor activity ->
DNA binding
IXR1, SOK2, SWI4
YGL062WPYC1NADPH regeneration, gluconeogenesis ->
coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways
pyruvate carboxylase activity ->
ligase activity\, forming carbon-carbon bonds
cytosol ->
cytoplasm
DIG1, GCR1, STE12
|YKL203C|TOR2cytoskeleton organization and biogenesis, ribosome biogenesis, signal transduction, Rho protein signal transduction, regulation of cell cycle, G1 phase of mitotic cell cycle, cell cycle dependent actin filament reorganization ->
cell organization and biogenesis, signal transduction, cell cycle, cytoplasm organization and biogenesis
phosphatidylinositol 3-kinase activity, protein binding ->
transferase activity\, transferring phosphorus-containing groups, protein binding, lipid kinase activity
vacuolar membrane, plasma membrane ->
cytoplasm, plasma membrane
BAS1, HIR1, REB1, RTG1
|YGR060W|ERG25ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism
C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity
endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system
HSF1, MAL13, MET4, NDD1, SWI5
YKL145WRPT1ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
ATPase activity, endopeptidase activity ->
purine nucleotide binding, peptidase activity, hydrolase activity\, acting on acid anhydrides
proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus
REB1
YGR253CPUP2ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) ->
catabolism, response to stress, sporulation, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
ABF1, HIR2, PHO4
YOR052CNO SYMBOL
YDL126CCDC48ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism ->
cell proliferation, cell death, macromolecule catabolism, transport, protein metabolism
ATPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleus, microsome, endoplasmic reticulum, cytosol ->
nucleus, membrane fraction, cytoplasm
DAL82, MAL33, SWI4
YKL054CDEF1response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism
nucleus ->
nucleus
YJR090CGRR1ubiquitin-dependent protein catabolism, G1/S transition of mitotic cell cycle ->
catabolism, cell proliferation, protein metabolism
ubiquitin-protein ligase activity, protein binding ->
ligase activity\, forming carbon-nitrogen bonds, protein binding
nuclear ubiquitin ligase complex, nucleus, cytoplasm, contractile ring (sensu Saccharomyces) ->
nucleus, site of polarized growth (sensu Fungi), cell cortex, cytoplasm, ubiquitin ligase complex
REB1
YOR362CPRE10ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
peptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
Main:protein metabolism (0.56)peptidase activity (0.33)cytoplasm (0.80)REB1 (0.40)
Score:0.380.170.910.171
P-value:1.337E-08 (ubiquitin-dependent protein catabolism)7.207E-05 (endopeptidase activity)6.134E-07 (proteasome complex (sensu Eukarya))1.378E-03 (REB1)

ALPHA1(1) AND LYS14(1) AND RPN4(1) => SimExpr(YGL201C) OR SimExpr(other) : 5 1

    EXPR: (0.174) LYS14 (P < 0.001) RPN4 (P < 0.258) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
YGL201CMCM6DNA unwinding, DNA replication initiation ->
cell cycle, DNA metabolism
chromatin binding, ATP dependent DNA helicase activity ->
chromatin binding, ATP dependent DNA helicase activity
cytoplasm, nucleus, pre-replicative complex ->
cytoplasm, nucleus
MCM1
YNL097CPHO23chromatin modification ->
nuclear organization and biogenesis, DNA metabolism
nucleus ->
nucleus
MAC1
|YGR060W|ERG25ergosterol biosynthesis ->
alcohol metabolism, lipid biosynthesis, steroid metabolism
C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity
endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system
HSF1, MAL13, MET4, NDD1, SWI5
YGR253CPUP2ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) ->
macromolecule catabolism, response to stress, sporulation (sensu Fungi), protein metabolism
endopeptidase activity ->
endopeptidase activity
proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
ABF1, HIR2, PHO4
YOR052CNO SYMBOL
YKL054CDEF1response to DNA damage, ubiquitin-dependent protein catabolism ->
response to stress, macromolecule catabolism, protein metabolism
nucleus ->
nucleus
Main:DNA metabolism (0.40)chromatin binding (0.33)nucleus (0.80)ABF1 (0.25)
Score:0.200.000.800.000
P-value:1.924E-01 (ubiquitin-dependent protein catabolism)1.308E+00 (hydrolase activity)4.424E-01 (endoplasmic reticulum)6.578E-01 (MAL13)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 35 6

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 19 3

    EXPR: (0.162) mRRPE (P < 0.000) PAC (P < 0.015) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
YPL266WDIM1rRNA modification, 35S primary transcript processing ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent
rRNA (adenine-N6\,N6-)-dimethyltransferase activity ->
transferase activity\, transferring one-carbon groups
nucleolus ->
nucleus
ARG81, STP2
|YOR381W|FRE3iron-siderochrome transport, iron ion homeostasis ->
iron-siderochrome transport, cation homeostasis
ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions
plasma membrane, integral to membrane ->
plasma membrane, integral to membrane
CIN5, PDR1, YAP6
YMR229CRRP5rRNA processing, processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
RNA binding, snoRNA binding ->
RNA binding
nucleolus, nucleolus organizer complex ->
nucleus
FHL1, RAP1
YJR002WMPP10rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent
small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YFR001WLOC1ribosomal large subunit biogenesis ->
ribosome biogenesis and assembly
mRNA binding ->
RNA binding
nucleus ->
nucleus
ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
|YMR259C|NO SYMBOLARG80, GCR2, GTS1, HIR1, SRD1
YHR196WUTP9processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YJL109CUTP10processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YJL033WHCA435S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
HIR2, USV1
YNL075WIMP4rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent
rRNA primary transcript binding ->
RNA binding
small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
USV1
YOR095CRKI1pentose-phosphate shunt ->
monosaccharide catabolism, main pathways of carbohydrate metabolism, oxidoreduction coenzyme metabolism, hexose metabolism, water-soluble vitamin metabolism
ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity
FHL1, FKH2, RAP1
YMR290CHAS1nucleolus, nuclear membrane ->
nucleus, endomembrane system
RAP1
YHR169WDBP835S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
YLR249WYEF3translational elongation ->
protein biosynthesis
translation elongation factor activity ->
translation factor activity\, nucleic acid binding
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YGL029WCGR1ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
nucleolus ->
nucleus
YKL056CNO SYMBOL
YJR070CNO SYMBOLGAT3, YAP5
YMR131CRRB1ribosome biogenesis ->
ribosome biogenesis and assembly
nucleolus ->
nucleus
FZF1, MATa1, RGT1
|YPR183W|DPM1N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system
SWI5
YJL069CUTP18ABF1
YMR239CRNT135S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
ribonuclease III activity ->
hydrolase activity\, acting on ester bonds, RNA binding
nucleolus ->
nucleus
YOL022CNO SYMBOLMAC1, MOT3, RTS2
Main:ribosome biogenesis and assembly (0.75)RNA binding (0.62)nucleus (0.81)RAP1 (0.20)
Score:0.560.360.700.048
P-value:1.227E-10 (ribosome biogenesis)3.388E-03 (RNA binding)3.803E-11 (nucleolus)7.433E-01 (USV1)

MCM1(1) AND STRE(1) => SimExpr(YOL087C) OR SimExpr(other) : 5 1

ALPHA1(1) AND ALPHA1'(1) AND STRE(1) => SimExpr(YOL087C) OR SimExpr(other) : 5 2

    EXPR: (0.177) ALPHA1' (P < 0.002) STRE (P < 0.035) ALPHA1 (P < 0.003)

ORFSYMBOLPFCTF
YPR184WGDB1glycogen catabolism ->
carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism
4-alpha-glucanotransferase activity, amylo-1\,6-glucosidase activity ->
transferase activity\, transferring hexosyl groups, hydrolase activity\, hydrolyzing O-glycosyl compounds
CIN5
YOL087CNO SYMBOLDAL82
|YNL098C|RAS2pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction
RAS small monomeric GTPase activity ->
guanyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides
plasma membrane ->
plasma membrane
ACE2, SKN7
|YIL052C|RPL34Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
RME1
YGL062WPYC1NADPH regeneration, gluconeogenesis ->
coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways
pyruvate carboxylase activity ->
pyruvate carboxylase activity
cytosol ->
cytoplasm
DIG1, GCR1, STE12
YKL035WUGP1protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism
UTP-glucose-1-phosphate uridylyltransferase activity ->
nucleotidyltransferase activity
YFL036WRPO41mitochondrial genome maintenance, transcription from mitochondrial promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
nucleotidyltransferase activity
mitochondrial matrix ->
cytoplasm
Main:biosynthesis (0.50)nucleotidyltransferase activity (0.33)cytoplasm (0.75)ACE2 (0.20)
Score:0.470.070.500.000
P-value:9.418E-02 (carbohydrate metabolism)4.324E-02 (nucleotidyltransferase activity)1.068E+00 (cytosol)5.887E-01 (DAL82)

RAP1(1) AND MCM1'(1) => SimExpr(YGR085C) OR SimExpr(other) : 15 6

MIG1(1) AND ABF1(1) => SimExpr(YKR046C) OR SimExpr(other) : 7 2

    EXPR: (0.171) ABF1 (P < 0.000) MIG1 (P < 0.005)

ORFSYMBOLPFCTF
YNL138WSRV2cytoskeleton organization and biogenesis, RAS protein signal transduction ->
cell organization and biogenesis, signal transduction
cytoskeletal protein binding, adenylate cyclase binding ->
cytoskeletal protein binding, adenylate cyclase binding
actin cortical patch (sensu Saccharomyces) ->
intracellular
ABF1
|YMR280C|CAT8gluconeogenesis, positive regulation of transcription from Pol II promoter ->
alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways
specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity
nucleus ->
intracellular
ABF1, REB1
YOR317WFAA1N-terminal protein myristoylation, lipid metabolism, lipid transport ->
biosynthesis, lipid metabolism, transport, protein metabolism
ligase activity ->
ligase activity
lipid particle ->
intracellular
ASH1, CIN5, HSF1, INO4, RAP1
YKR046CPET10lipid particle ->
intracellular
ABF1
YAL016WTPD3protein biosynthesis, actin filament organization, mitotic spindle checkpoint, bud growth, protein amino acid dephosphorylation ->
biosynthesis, cell organization and biogenesis, asexual reproduction, phosphorus metabolism, cell proliferation, cell cycle, protein metabolism
protein phosphatase type 2A activity ->
protein phosphatase type 2A activity
protein phosphatase type 2A complex, bud neck, nucleus, cytoplasm, shmoo tip, bud tip, spindle pole body ->
protein phosphatase type 2A complex, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), intracellular
ABF1
YKL034WTUL1protein transport ->
transport
ligase activity ->
ligase activity
intracellular ->
intracellular
YPL111WCAR1arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism
arginase activity ->
arginase activity
cytosol ->
intracellular
GCN4
YOR322CNO SYMBOLABF1
|YDL020C|RPN4ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism
endopeptidase activity ->
endopeptidase activity
proteasome regulatory particle (sensu Eukarya) ->
intracellular
ABF1, CBF1, HSF1, PUT3, YAP1
Main:biosynthesis (0.43)ligase activity (0.29)intracellular (1.00)ABF1 (0.75)
Score:0.380.051.000.571
P-value:1.690E+00 (cytoskeleton organization and biogenesis)1.516E-01 (ligase activity)2.216E-02 (lipid particle)7.301E-05 (ABF1)

ALPHA1(1) AND ALPHA1'(1) AND STRE(1) => SimExpr(YPR184W) OR SimExpr(other) : 5 2

MIG1(1) AND ABF1(1) => SimExpr(YAL016W) OR SimExpr(other) : 7 2

mRRPE(1) AND PAC(1) => SimExpr(YOR095C) OR SimExpr(other) : 57 19

mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YOR095C) OR SimExpr(other) : 10 4

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR095C) OR SimExpr(other) : 16 6

SFF(1) AND MCB(1) AND ATRepeat(1) => SimExpr(YPR185W) OR SimExpr(other) : 6 2

RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YMR194W) OR SimExpr(other) : 10 4

    EXPR: (0.169) SFF (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.059)

ORFSYMBOLPFCTF
YMR194WRPL36Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
YKR092CSRP40nucleocytoplasmic transport ->
nucleocytoplasmic transport
chaperone activity ->
chaperone activity
nucleolus ->
nucleus
CUP9, MET4, RAP1
YLR441CRPS1Aprotein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, YAP5
|YMR224C|MRE11DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication ->
mitotic recombination, M phase, DNA catabolism, DNA recombination, DNA repair
endonuclease activity, 3'-5' exonuclease activity, protein binding ->
endonuclease activity, 3'-5' exonuclease activity, protein binding
nucleus ->
nucleus
RAP1
YNL069CRPL16Bprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YLR344WRPL26Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, RAP1
YOR312CRPL20Bprotein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, FKH2, GAT3, RAP1
YJR145CRPS4Aprotein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YLR249WYEF3translational elongation ->
protein biosynthesis
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
|YGL115W|SNF4regulation of transcription from Pol II promoter, peroxisome organization and biogenesis ->
regulation of transcription, organelle organization and biogenesis, transcription\, DNA-dependent
protein kinase activator activity ->
protein kinase activator activity
plasma membrane, nucleus, cytoplasm ->
plasma membrane, nucleus, cytoplasm
BAS1, CAD1, MAC1, NRG1, PDR1, RAP1, SMP1, YAP5
|YJL217W|NO SYMBOLCIN5, MAC1, PHD1, SWI5, YAP6
|YLR452C|SST2signal transduction, adaptation to pheromone during conjugation with cellular fusion ->
signal transduction, conjugation with cellular fusion, perception of chemical substance, sensory perception
GTPase activator activity ->
GTPase activator activity
plasma membrane ->
plasma membrane
DIG1, FHL1, RAP1, STE12
YOR369CRPS12protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YKL006WRPL14Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
Main:protein biosynthesis (0.69)structural constituent of ribosome (0.62)cytoplasm (0.77)RAP1 (0.79)
Score:0.460.360.630.747
P-value:3.886E-05 (protein biosynthesis)2.931E-06 (structural constituent of ribosome)4.999E-07 (cytosolic ribosome (sensu Eukarya))3.510E-10 (RAP1)

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YMR194W) : 6

RAP1(1) AND PAC(1) => SimExpr(YGR283C) : 5

    EXPR: (0.145) PAC (P < 0.008) RAP1 (P < 0.004)

ORFSYMBOLPFCTF
YMR014WBUD22bud site selection ->
cytokinesis, cytoplasm organization and biogenesis
nucleus ->
nucleus
CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YGR283CNO SYMBOLACE2, RAP1, SMP1
YKR092CSRP40nucleocytoplasmic transport ->
intracellular transport
chaperone activity ->
chaperone activity
nucleolus ->
nucleus
CUP9, MET4, RAP1
YLR249WYEF3translational elongation ->
macromolecule biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YDR449CUTP6processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription
snoRNA binding ->
snoRNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
Main:cytoplasm organization and biogenesis (0.50)translation elongation factor activity (0.33)nucleus (0.75)RAP1 (0.60)
Score:0.170.000.670.600
P-value:1.792E+00 (cytoplasm organization and biogenesis)8.180E-01 (nucleic acid binding)1.067E-01 (nucleolus)3.225E-02 (HIR2)

RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YOR369C) OR SimExpr(other) : 10 4

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YOR369C) : 5

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YOR369C) : 6

RAP1(1) AND MCM1'(1) => SimExpr(YDL130W) OR SimExpr(other) : 15 6

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 5 1

RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 7 3

    EXPR: (0.160) SFF' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.170)

ORFSYMBOLPFCTF
YMR194WRPL36Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
|YOL160W|NO SYMBOLARO80, NRG1, PHO4, RLM1, SIP4, SWI6
YNL024CNO SYMBOLGRF10(Pho2)
YGR085CRPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosome biogenesis and assembly
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MIG1
|YPL189W|GUP2membrane ->
membrane
RFX1
YPL131WRPL5protein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosome biogenesis and assembly
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1
YLR344WRPL26Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, RAP1
YLR249WYEF3translational elongation ->
protein biosynthesis
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
ribosome
INO2, INO4
|YGR260W|TNA1nicotinamide mononucleotide transport ->
nicotinamide mononucleotide transport
nicotinamide mononucleotide permease activity ->
nicotinamide mononucleotide permease activity
integral to plasma membrane ->
membrane
HIR2, SUM1
YOR369CRPS12protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
Main:protein biosynthesis (0.86)structural constituent of ribosome (0.71)ribosome (0.75)FHL1 (0.50)
Score:0.710.480.570.244
P-value:4.861E-03 (protein biosynthesis)1.080E-03 (structural constituent of ribosome)4.143E-04 (ribosome)1.468E-04 (FHL1)

RAP1(1) AND SFF(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 7 2

    EXPR: (0.152) SFF (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.136)

ORFSYMBOLPFCTF
YMR194WRPL36Aprotein biosynthesis ->
macromolecule biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
|YOL160W|NO SYMBOLARO80, NRG1, PHO4, RLM1, SIP4, SWI6
YNL024CNO SYMBOLGRF10(Pho2)
YGR085CRPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
macromolecule biosynthesis, cytoplasm organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MIG1
YPL131WRPL5protein biosynthesis, ribosomal large subunit assembly and maintenance ->
macromolecule biosynthesis, cytoplasm organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1
YLR344WRPL26Aprotein biosynthesis ->
macromolecule biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, RAP1
YLR249WYEF3translational elongation ->
macromolecule biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YOR369CRPS12protein biosynthesis ->
macromolecule biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
|YLR208W|SEC13nonselective vesicle assembly, ER to Golgi transport, ER-associated protein catabolism ->
vesicle-mediated transport, intracellular transport, macromolecule catabolism, secretory pathway, protein metabolism
cytoplasm, COPII vesicle coat, nuclear pore, extrinsic to plasma membrane ->
nucleus, extrinsic to membrane, cytoplasm, membrane coat, integral to membrane, endomembrane system, plasma membrane
Main:protein metabolism (1.00)structural constituent of ribosome (0.83)cytoplasm (1.00)FHL1 (0.62)
Score:1.000.671.000.393
P-value:2.149E-03 (protein biosynthesis)5.672E-04 (structural constituent of ribosome)1.623E-04 (ribosome)6.829E-05 (FHL1)

RAP1(1) AND ALPHA1'(1) AND SFF(1) AND SCB(1) => SimExpr(YPL131W) : 5

    EXPR: (0.116) ALPHA1' (P < 0.000) SFF (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.042)

ORFSYMBOLPFCTF
YMR194WRPL36Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
YNL024CNO SYMBOLGRF10(Pho2)
YPL131WRPL5protein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosomal large subunit assembly and maintenance
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, GAT3, RAP1
YLR344WRPL26Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, RAP1
YOR369CRPS12protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
Main:protein biosynthesis (1.00)structural constituent of ribosome (1.00)cytosolic ribosome (sensu Eukarya) (1.00)FHL1 (0.80)
Score:1.001.001.000.600
P-value:6.205E-03 (protein biosynthesis)4.455E-04 (structural constituent of ribosome)2.052E-04 (cytosolic ribosome (sensu Eukarya))7.961E-05 (FHL1)

RAP1(1) AND ALPHA1'(1) AND SFF'(1) AND SCB(1) => SimExpr(YPL131W) : 5

    EXPR: (0.116) ALPHA1' (P < 0.000) SFF' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.043)

ORFSYMBOLPFCTF
YMR194WRPL36Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
YNL024CNO SYMBOLGRF10(Pho2)
YPL131WRPL5protein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosomal large subunit assembly and maintenance
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, GAT3, RAP1
YLR344WRPL26Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, RAP1
YOR369CRPS12protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
Main:protein biosynthesis (1.00)structural constituent of ribosome (1.00)cytosolic ribosome (sensu Eukarya) (1.00)FHL1 (0.80)
Score:1.001.001.000.600
P-value:6.205E-03 (protein biosynthesis)4.455E-04 (structural constituent of ribosome)2.052E-04 (cytosolic ribosome (sensu Eukarya))7.961E-05 (FHL1)

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YNL024C) : 6

RAP1(1) AND MCM1'(1) => SimExpr(YKL006W) OR SimExpr(other) : 15 6

ALPHA2(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR249W) OR SimExpr(other) : 7 2

    EXPR: (0.135) ALPHA2 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.009)

ORFSYMBOLPFCTF
YKL172WEBP2rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
nucleolus ->
nucleus
ABF1, FZF1, RFX1
|YJL033W|HCA435S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
HIR2, USV1
YMR049CERB1rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
RTG3
YLR249WYEF3translational elongation ->
protein biosynthesis
translation elongation factor activity ->
translation factor activity\, nucleic acid binding
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YGL029WCGR1ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
nucleolus ->
nucleus
YJR070CNO SYMBOLGAT3, YAP5
YLR222CUTP13processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1
|YPR183W|DPM1N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system
SWI5
YNR046WNO SYMBOLABF1
Main:RNA processing (0.71)RNA binding (0.50)nucleus (0.67)ABF1 (0.38)
Score:0.520.170.530.107
P-value:5.052E-05 (rRNA processing)9.380E-01 (RNA binding)2.195E-03 (nucleolus)2.138E-01 (ABF1)

RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YLR249W) OR SimExpr(other) : 10 4

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YPR080W) OR SimExpr(other) : 5 1

RPN4(1) => SimExpr(YDL126C) OR SimExpr(other) : 35 17

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR290C) OR SimExpr(other) : 7 1

SFF'(1) AND STE12(1) AND PAC(1) => SimExpr(YJL069C) OR SimExpr(other) : 5 1

ALPHA1(1) AND RPN4(1) => SimExpr(YOR052C) OR SimExpr(other) : 13 6

mRRPE(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) OR SimExpr(other) : 5 1

ALPHA1(1) AND ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 9 4

    EXPR: (0.192) ALPHA1' (P < 0.000) mRRPE (P < 0.002) PAC (P < 0.024) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
|YOR381W|FRE3iron-siderochrome transport, iron ion homeostasis ->
iron-siderochrome transport, di-\, tri-valent inorganic cation homeostasis, metal ion homeostasis
ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions
plasma membrane, integral to membrane ->
plasma membrane, integral to membrane
CIN5, PDR1, YAP6
YMR229CRRP5rRNA processing, processing of 20S pre-rRNA ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter
RNA binding, snoRNA binding ->
RNA binding
nucleolus, nucleolus organizer complex ->
nucleus
FHL1, RAP1
|YFR001W|LOC1ribosomal large subunit biogenesis ->
ribosome biogenesis
mRNA binding ->
RNA binding
nucleus ->
nucleus
ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
|YHR196W|UTP9processing of 20S pre-rRNA ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YJL109CUTP10processing of 20S pre-rRNA ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YJL033WHCA435S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
HIR2, USV1
YNL075WIMP4rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter
rRNA primary transcript binding ->
RNA binding
small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
USV1
YOR095CRKI1pentose-phosphate shunt ->
hexose catabolism, main pathways of carbohydrate metabolism, pyridine nucleotide metabolism, glucose metabolism
ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity
FHL1, FKH2, RAP1
YHR169WDBP835S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
YGL029WCGR1ribosome biogenesis, rRNA processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter
nucleolus ->
nucleus
YJR070CNO SYMBOLGAT3, YAP5
|YPR183W|DPM1N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
glycoprotein biosynthesis, glycerophospholipid biosynthesis, lipoprotein biosynthesis, glycerophospholipid metabolism, protein modification
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system
SWI5
YOL022CNO SYMBOLMAC1, MOT3, RTS2
Main:ribosome biogenesis (0.73)RNA binding (0.70)nucleus (0.80)USV1 RAP1 FHL1 (0.22)
Score:0.510.470.620.056
P-value:1.250E-07 (ribosome biogenesis)4.011E-04 (RNA binding)1.704E-06 (nucleolus)1.899E-01 (USV1)

ALPHA1(1) AND RPN4(1) => SimExpr(YKL145W) OR SimExpr(other) : 13 6

ALPHA1'(1) AND GCN4(1) AND SCB(1) => SimExpr(YDR473C) OR SimExpr(other) : 5 2

    EXPR: (0.175) ALPHA1' (P < 0.000) GCN4 (P < 0.028) SCB (P < 0.002)

ORFSYMBOLPFCTF
YFL028CCAF16regulation of transcription\, DNA-dependent ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity
CCR4-NOT complex, cytoplasm ->
nucleus, cytoplasm
YFR028CCDC14DNA dependent DNA replication, protein amino acid dephosphorylation, regulation of exit from mitosis ->
phosphorus metabolism, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism
protein phosphatase activity ->
protein phosphatase activity
nucleus, spindle pole body, nucleolus ->
cytoplasm, nucleus, microtubule organizing center
|YMR300C|ADE4purine base metabolism ->
aromatic compound metabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
amidophosphoribosyltransferase activity ->
amidophosphoribosyltransferase activity
BAS1
YDR473CPRP3mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
pre-mRNA splicing factor activity ->
pre-mRNA splicing factor activity
small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ARG80, ARG81, DOT6, FZF1, GCR2, HAP4, HAP5, NRG1, RIM101, RLM1, RTG1, RTG3, SFP1, SRD1, STP1, THI2
YLR271WNO SYMBOL
YKL211CTRP3tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity
CRZ1
|YPR145W|ASN1asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis
asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity
DAL81, GCN4, GLN3, MET4, RAP1, SUM1
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67)pre-mRNA splicing factor activity (0.17)nucleus (1.00)GCR2 (0.25)
Score:0.530.001.000.000
P-value:4.613E-02 (aromatic compound metabolism)1.306E+00 (enzyme activity)2.826E+00 (nucleus)1.000E+00

ALPHA1(1) AND RPN4(1) => SimExpr(YNL097C) OR SimExpr(other) : 14 5

LYS14(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 6 2

    EXPR: (0.181) LYS14 (P < 0.000) ALPHA1' (P < 0.000) PAC (P < 0.139)

ORFSYMBOLPFCTF
YGR191WHIP1manganese ion transport, histidine transport ->
transport, organic acid transport
histidine transporter activity ->
carboxylic acid transporter activity
plasma membrane ->
plasma membrane
GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
|YGR178C|PBP1mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
cytoplasm, nucleus ->
cytoplasm, nucleus
CIN5, DOT6, MSS11
YML093WUTP14processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YDR361CBCP1ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
YGL099WLSG1conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction
GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
cytoplasm ->
cytoplasm
PHO4
|YOL075C|NO SYMBOLCRZ1, DAL82, SIP4
YJR070CNO SYMBOLGAT3, YAP5
YGR280CPXR135S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
Main:cell organization and biogenesis (0.60)RNA binding (0.50)nucleus (0.60)YAP1 GLN3 (0.33)
Score:0.600.170.400.067
P-value:6.030E-02 (ribosome biogenesis)6.400E-01 (RNA binding)2.761E-01 (nucleolus)9.199E-02 (GLN3)

ALPHA2(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YLR222C) OR SimExpr(other) : 5 2

    EXPR: (0.165) ALPHA2 (P < 0.000) ALPHA1' (P < 0.000) PAC (P < 0.120)

ORFSYMBOLPFCTF
YJL033WHCA435S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleus
HIR2, USV1
YMR049CERB1rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RTG3
YGL029WCGR1ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleolus ->
nucleus
YJR070CNO SYMBOLGAT3, YAP5
YLR222CUTP13processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
ABF1
|YPR183W|DPM1N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system
SWI5
|YPL106C|SSE1protein folding ->
protein metabolism
co-chaperone activity ->
co-chaperone activity
cytoplasm ->
cytoplasm
HSF1, MSN4
Main:cell organization and biogenesis (0.67)RNA binding (0.50)nucleus (0.60)ABF1 (0.17)
Score:0.470.170.400.000
P-value:4.417E-04 (rRNA processing)6.066E-01 (RNA binding)1.424E-02 (nucleolus)6.376E-01 (USV1)

ALPHA2(1) AND ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR222C) OR SimExpr(other) : 5 1

    EXPR: (0.146) ALPHA2 (P < 0.000) ALPHA1' (P < 0.000) mRRPE (P < 0.004) PAC (P < 0.028)

ORFSYMBOLPFCTF
YJL033WHCA435S primary transcript processing ->
rRNA processing
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
nucleolus
HIR2, USV1
YMR049CERB1rRNA processing ->
rRNA processing
RTG3
YGL029WCGR1ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing
nucleolus ->
nucleolus
YJR070CNO SYMBOLGAT3, YAP5
YLR222CUTP13processing of 20S pre-rRNA ->
rRNA processing
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
ABF1
|YPR183W|DPM1N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
protein amino acid glycosylation, phosphoinositide biosynthesis, protein lipidation, phosphoinositide metabolism
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network
SWI5
Main:rRNA processing (0.80)RNA binding (0.67)nucleolus (0.75)ABF1 (0.20)
Score:0.600.330.500.000
P-value:1.829E-04 (rRNA processing)4.564E-01 (RNA binding)7.182E-03 (nucleolus)4.272E-01 (USV1)

ABF1(1) AND PAC(1) => SimExpr(YNR046W) OR SimExpr(other) : 12 3

ABF1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YNR046W) OR SimExpr(other) : 9 1

    EXPR: (0.132) ABF1 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.002)

ORFSYMBOLPFCTF
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
YNL292WPUS4tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
pseudouridylate synthase activity ->
pseudouridylate synthase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
YNL112WDBP2RNA helicase activity ->
RNA helicase activity
bud neck ->
site of polarized growth (sensu Fungi)
YKL014CNO SYMBOLABF1
YKL172WEBP2rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleolus ->
nucleus
ABF1, FZF1, RFX1
YLR197WSIK1rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex
DAL81, HAL9
YGR187CHGH1ABF1, HAP3, HIR1, RCS1, RTG1
YJL050WMTR435S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA helicase activity, ATP dependent helicase activity, RNA dependent ATPase activity
nucleolus ->
nucleus
|YJL069C|UTP18ABF1
YNR046WNO SYMBOLABF1
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00)RNA helicase activity (0.50)nucleus (0.83)ABF1 (0.62)
Score:1.000.170.670.393
P-value:5.162E-03 (transcription from Pol I promoter)4.041E-02 (RNA helicase activity)2.661E-03 (nucleolus)2.954E-03 (ABF1)

ALPHA2(1) AND RPN4(1) => SimExpr(YOL038W) OR SimExpr(other) : 7 2

    EXPR: (0.179) ALPHA2 (P < 0.002) RPN4 (P < 0.490)

ORFSYMBOLPFCTF
YGR184CUBR1protein polyubiquitination, protein monoubiquitination ->
ubiquitin-dependent protein catabolism, protein modification
ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity
proteasome complex (sensu Eukarya) ->
cytosol, endoplasmic reticulum, nucleus
HMS1, REB1, RIM101
YOR097CNO SYMBOL
|YJL045W|NO SYMBOLMBP1, ROX1
YGL096WTOS8transcription factor activity ->
transcription factor activity
IXR1, SOK2, SWI4
YOL038WPRE6ubiquitin-dependent protein catabolism ->
ubiquitin-dependent protein catabolism
endopeptidase activity ->
endopeptidase activity
proteasome core complex (sensu Eukarya) ->
cytosol, endoplasmic reticulum, nucleus
|YGR060W|ERG25ergosterol biosynthesis ->
ergosterol biosynthesis
C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity
endoplasmic reticulum membrane, plasma membrane ->
endoplasmic reticulum, plasma membrane, nuclear envelope-endoplasmic reticulum network
HSF1, MAL13, MET4, NDD1, SWI5
YHR027CRPN1ubiquitin-dependent protein catabolism ->
ubiquitin-dependent protein catabolism
endopeptidase activity, receptor activity ->
endopeptidase activity, receptor activity
proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytosol, endoplasmic reticulum, cytoplasm, nucleus
YDL126CCDC48ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism ->
ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, misfolded or incompletely synthesized protein catabolism
ATPase activity ->
ATPase activity
nucleus, microsome, endoplasmic reticulum, cytosol ->
nucleus, vesicular fraction, endoplasmic reticulum, cytosol
DAL82, MAL33, SWI4
YKL054CDEF1response to DNA damage, ubiquitin-dependent protein catabolism ->
response to DNA damage, ubiquitin-dependent protein catabolism
nucleus ->
nucleus
Main:ubiquitin-dependent protein catabolism (0.83)endopeptidase activity (0.33)endoplasmic reticulum (0.83)SWI4 (0.40)
Score:0.670.070.930.100
P-value:2.376E-05 (ubiquitin-dependent protein catabolism)4.572E-02 (endopeptidase activity)1.385E-03 (proteasome complex (sensu Eukarya))7.177E-01 (MAL33)

ALPHA2(1) AND SFF(1) AND RPN4(1) => SimExpr(YOL038W) : 6

    EXPR: (0.151) ALPHA2 (P < 0.000) SFF (P < 0.000) RPN4 (P < 0.112)

ORFSYMBOLPFCTF
YGR184CUBR1protein polyubiquitination, protein monoubiquitination ->
ubiquitin-dependent protein catabolism, protein modification
ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity
proteasome complex (sensu Eukarya) ->
cytosol, endoplasmic reticulum, nucleus
HMS1, REB1, RIM101
YOR097CNO SYMBOL
YGL096WTOS8transcription factor activity ->
transcription factor activity
IXR1, SOK2, SWI4
YOL038WPRE6ubiquitin-dependent protein catabolism ->
ubiquitin-dependent protein catabolism
endopeptidase activity ->
endopeptidase activity
proteasome core complex (sensu Eukarya) ->
cytosol, endoplasmic reticulum, nucleus
YDL126CCDC48ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism ->
ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, misfolded or incompletely synthesized protein catabolism
ATPase activity ->
ATPase activity
nucleus, microsome, endoplasmic reticulum, cytosol ->
nucleus, vesicular fraction, endoplasmic reticulum, cytosol
DAL82, MAL33, SWI4
YKL054CDEF1response to DNA damage, ubiquitin-dependent protein catabolism ->
response to DNA damage, ubiquitin-dependent protein catabolism
nucleus ->
nucleus
Main:ubiquitin-dependent protein catabolism (1.00)transcription factor activity (0.25)nucleus (1.00)SWI4 (0.67)
Score:1.000.001.000.333
P-value:1.086E-04 (ubiquitin-dependent protein catabolism)1.635E+00 (hydrolase activity)2.147E-02 (proteasome complex (sensu Eukarya))1.888E-01 (SWI4)

RPN4(1) => SimExpr(YHR027C) OR SimExpr(other) : 35 17

ABF1(1) AND RPN4(1) => SimExpr(YHR027C) OR SimExpr(other) : 5 2

ABF1(1) AND PAC(1) => SimExpr(YKL172W) OR SimExpr(other) : 13 2

ABF1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YKL172W) : 10

ABF1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YKL014C) : 5

ABF1(1) AND STE12(1) => SimExpr(YFL008W) OR SimExpr(other) : 5 1

    EXPR: (0.153) ABF1 (P < 0.001) STE12 (P < 0.000)

ORFSYMBOLPFCTF
YLR429WCRN1actin filament organization, microtubule-based process ->
cytoplasm organization and biogenesis
actin cross-linking activity, microtubule binding ->
protein binding
actin cortical patch (sensu Saccharomyces) ->
cell cortex, cytoplasm
YDR303CRSC3regulation of transcription\, DNA-dependent, regulation of cell cycle ->
cell cycle, transcription
DNA binding ->
DNA binding
RSC complex, nucleus ->
nucleus
YNL258CDSL1retrograde (Golgi to ER) transport ->
secretory pathway, vesicle-mediated transport
endoplasmic reticulum ->
cytoplasm
ABF1, ARG80, HAP5, YJL206C
|YJL069C|UTP18ABF1
YFL008WSMC1mitotic chromosome segregation ->
cell cycle, mitotic cell cycle
DNA secondary structure binding, AT DNA binding, double-stranded DNA binding, ATPase activity ->
DNA binding, double-stranded DNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nuclear cohesin complex ->
chromosome, nucleus
MBP1
YKL022CCDC16mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cytoplasm organization and biogenesis, macromolecule catabolism, cell cycle, M phase, mitotic cell cycle, protein metabolism
ubiquitin-protein ligase activity, protein binding ->
ligase activity\, forming carbon-nitrogen bonds, protein binding
anaphase-promoting complex ->
nucleus, ubiquitin ligase complex
AZF1
Main:cell cycle (0.60)protein binding (0.50)nucleus (0.60)ABF1 (0.50)
Score:0.400.330.400.167
P-value:1.792E-02 (mitotic chromosome segregation)3.414E-01 (protein binding)2.133E+00 (nucleus)3.489E-01 (ABF1)

mRRPE(1) AND PAC(1) => SimExpr(YLR197W) OR SimExpr(other) : 60 16

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YML093W) OR SimExpr(other) : 7 1

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR052W) OR SimExpr(other) : 7 1

SFF'(1) AND SWI5(1) AND Yap1(1) => SimExpr(YOR173W) OR SimExpr(other) : 5 2

    EXPR: (0.151) SFF' (P < 0.000) SWI5 (P < 0.000) Yap1 (P < 0.008)

ORFSYMBOLPFCTF
YPL091WGLR1response to oxidative stress ->
response to oxidative stress
glutathione reductase (NADPH) activity ->
glutathione reductase (NADPH) activity
YOR173WDCS2CAD1
|YFL056C|AAD6aldehyde metabolism ->
aldehyde metabolism
benzyl alcohol dehydrogenase activity ->
benzyl alcohol dehydrogenase activity
ACE2, YAP1
YFR014CCMK1protein amino acid phosphorylation, signal transduction ->
protein amino acid phosphorylation, signal transduction
calmodulin-dependent protein kinase I activity ->
calmodulin-dependent protein kinase I activity
cytoplasm ->
cytoplasm
USV1
YOL048CNO SYMBOLSKN7
YDR453CTSA2regulation of redox homeostasis ->
regulation of redox homeostasis
thioredoxin peroxidase activity ->
thioredoxin peroxidase activity
nucleus ->
nucleus
SWI4
|YPR005C|HAL1salinity response, transcription initiation from Pol II promoter ->
salinity response, transcription initiation from Pol II promoter
cytoplasm ->
cytoplasm
CIN5
Main:signal transduction (0.20)calmodulin-dependent protein kinase I activity (0.25)cytoplasm (0.67)SWI4 (0.17)
Score:0.000.000.330.000
P-value:3.521E-01 (response to stress)4.856E-02 (oxidoreductase activity)4.860E+00 (cytoplasm)4.959E-01 (USV1)

SFF(1) AND SWI5(1) AND Yap1(1) => SimExpr(YOR173W) OR SimExpr(other) : 5 2

    EXPR: (0.151) SFF (P < 0.000) SWI5 (P < 0.000) Yap1 (P < 0.010)

ORFSYMBOLPFCTF
YPL091WGLR1response to oxidative stress ->
response to oxidative stress
glutathione reductase (NADPH) activity ->
glutathione reductase (NADPH) activity
YOR173WDCS2CAD1
|YFL056C|AAD6aldehyde metabolism ->
aldehyde metabolism
benzyl alcohol dehydrogenase activity ->
benzyl alcohol dehydrogenase activity
ACE2, YAP1
YFR014CCMK1protein amino acid phosphorylation, signal transduction ->
protein amino acid phosphorylation, signal transduction
calmodulin-dependent protein kinase I activity ->
calmodulin-dependent protein kinase I activity
cytoplasm ->
cytoplasm
USV1
YOL048CNO SYMBOLSKN7
YDR453CTSA2regulation of redox homeostasis ->
regulation of redox homeostasis
thioredoxin peroxidase activity ->
thioredoxin peroxidase activity
nucleus ->
nucleus
SWI4
|YPR005C|HAL1salinity response, transcription initiation from Pol II promoter ->
salinity response, transcription initiation from Pol II promoter
cytoplasm ->
cytoplasm
CIN5
Main:signal transduction (0.20)calmodulin-dependent protein kinase I activity (0.25)cytoplasm (0.67)SWI4 (0.17)
Score:0.000.000.330.000
P-value:3.521E-01 (response to stress)4.856E-02 (oxidoreductase activity)4.860E+00 (cytoplasm)4.959E-01 (USV1)

ALPHA1'(1) AND BAS1(1) AND STE12(1) => SimExpr(YJL005W) OR SimExpr(other) : 5 2

    EXPR: (0.186) ALPHA1' (P < 0.004) BAS1 (P < 0.024) STE12 (P < 0.005)

ORFSYMBOLPFCTF
YJL005WCYR1meiosis, G-protein signaling\, coupled to cAMP nucleotide second messenger, RAS protein signal transduction, regulation of cell cycle ->
nuclear division, G-protein coupled receptor protein signaling pathway, RAS protein signal transduction, regulation of cell cycle, cyclic-nucleotide-mediated signaling
adenylate cyclase activity ->
adenylate cyclase activity
plasma membrane ->
plasma membrane
YMR019WSTB4DNA binding ->
DNA binding
nucleus ->
nucleus
PHD1, SKN7, SWI4
|YPR015C|NO SYMBOL
YLR328WNMA1nicotinamide adenine dinucleotide metabolism ->
pyridine nucleotide metabolism
nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity
CIN5, MSN1, ROX1
YDR462WMRPL28protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
mitochondrial large ribosomal subunit ->
mitochondrial large ribosomal subunit
ABF1
YMR148WNO SYMBOL
|YOR212W|STE4signal transduction during conjugation with cellular fusion ->
G-protein coupled receptor protein signaling pathway, conjugation with cellular fusion, chemosensory perception
heterotrimeric G-protein GTPase activity ->
heterotrimeric G-protein GTPase activity
heterotrimeric G-protein complex, plasma membrane, shmoo tip ->
heterotrimeric G-protein complex, plasma membrane, shmoo tip
Main:G-protein coupled receptor protein signaling pathway (0.50)nicotinamide-nucleotide adenylyltransferase activity (0.20)plasma membrane (0.50)ABF1 (0.33)
Score:0.170.000.170.000
P-value:9.778E-03 (G-protein coupled receptor protein signaling pathway)2.754E+00 (binding)4.795E-01 (plasma membrane)2.021E-01 (MSN1)

RPN4(1) => SimExpr(YFL056C) OR SimExpr(other) : 37 15

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YMR310C) : 5

AVERAGE SCORES:

P
  SCORE: 0.612 (Part of genes covered by "Main": 0.711) (No. rules=58/59)
  P-VALUE: 0.638
F
  SCORE: 0.263 (Part of genes covered by "Main": 0.508) (No. rules=57/59)
  P-VALUE: 0.386
C
  SCORE: 0.694 (Part of genes covered by "Main": 0.789) (No. rules=57/59)
  P-VALUE: 0.614
TF
  SCORE: 0.244 (Part of genes covered by "Main": 0.448) (No. rules=57/59)
  P-VALUE: 0.351
EXPRESSION: 0.729 (59)