Binding site rules

m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) AND PDR(1) => SimExpr(YLR304C) OR SimExpr(other) : 6 2

EXPR: (0.222) m_tricarboxylic-acid_pathway_orfnum2SD_n3 (P < 0.058) PDR (P < 0.021)

ORF SYMBOL P F C TF
|YGR067C| NO SYMBOL ABF1, ASH1, RGM1
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
|YOR378W| NO SYMBOL MTH1, RFX1, SWI4
YMR272C SCS7 fatty acid metabolism ->
lipid metabolism, organic acid metabolism oxidoreductase activity ->
oxidoreductase activity endoplasmic reticulum ->
cytoplasm IXR1, SUM1
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane
YPL250C ICY2 HSF1, MET4
YDR281C PHM6 PHO4, SUM1
YLR441C RPS1A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, YAP5
Main: biosynthesis (0.50) aconitate hydratase activity (0.25) cytoplasm (0.75) SUM1 (0.29)
Score: 0.33 0.00 0.50 0.048
P-value: 5.696E-01 (carboxylic acid metabolism) 2.641E+00 (enzyme activity) 1.346E+00 (cytosol) 1.413E-01 (SUM1)

m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YLR304C) OR SimExpr(other) : 7 3

EXPR: (0.193) m_anion_transporters_orfnum2SD_n15 (P < 0.000) m_tricarboxylic-acid_pathway_orfnum2SD_n3 (P < 0.002)

ORF SYMBOL P F C TF
|YFL004W| VTC2 protein localization, vacuole fusion (non-autophagic) ->
protein metabolism, cell organization and biogenesis vacuolar membrane ->
cytoplasm CIN5, GCN4, STE12, YAP1, YAP6
|YLR335W| NUP2 mRNA-nucleus export, rRNA-nucleus export, snRNA-nucleus export, tRNA-nucleus export, NLS-bearing substrate-nucleus import, snRNP protein-nucleus import, mRNA-binding (hnRNP) protein-nucleus import, ribosomal protein-nucleus import, protein-nucleus export, nuclear pore organization and biogenesis ->
intracellular transport, intracellular protein transport, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transport structural molecule activity ->
structural molecule activity nuclear pore ->
nucleus, integral to membrane, endomembrane system
|YGR244C| LSC2 tricarboxylic acid cycle, succinyl-CoA metabolism ->
carbohydrate metabolism, coenzymes and prosthetic group metabolism, energy pathways succinate-CoA ligase (ADP-forming) activity ->
ligase activity\, forming carbon-sulfur bonds mitochondrion ->
cytoplasm ARO80
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
carbon-oxygen lyase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YLR168C NO SYMBOL HAP4
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
oxidoreductase activity\, acting on diphenols and related substances as donors, primary active transporter activity, cation transporter activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
purine nucleotide binding, multidrug transporter activity, primary active transporter activity, hydrolase activity\, acting on acid anhydrides plasma membrane ->
plasma membrane
YNR001C CIT1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis citrate (SI)-synthase activity ->
carbon-carbon lyase activity mitochondrial matrix, mitochondrion ->
cytoplasm RGM1
YGR086C PIL1 ASH1, SWI5
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on CH-OH group of donors mitochondrial matrix, mitochondrion ->
cytoplasm MET4
Main: energy pathways (0.62) primary active transporter activity (0.29) cytoplasm (0.75) HAP4 YAP6 CIN5 (0.25)
Score: 0.43 0.05 0.54 0.071
P-value: 1.679E-06 (tricarboxylic acid cycle) 1.956E-01 (primary active transporter activity) 4.344E-02 (mitochondrion) 9.811E-02 (HAP4)

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn(1) => SimExpr(YLR304C) OR SimExpr(other) : 5 2

EXPR: (0.205) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn (P < 0.004) m_other_pheromone_response_activities_orfnum2SD_n8 (P < 0.013)

ORF SYMBOL P F C TF
|YMR056C| AAC1 ATP/ADP exchange ->
purine nucleotide transport ATP/ADP antiporter activity ->
ATP/ADP antiporter activity mitochondrial inner membrane ->
mitochondrion, inner membrane DAL81, NRG1, RCS1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
pseudohyphal growth, sporulation (sensu Saccharomyces), G-protein coupled receptor protein signaling pathway, RAS protein signal transduction, cyclic-nucleotide-mediated signaling RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
|YML111W| BUL2 protein polyubiquitination, protein monoubiquitination ->
proteolysis and peptidolysis, protein modification PDR1, SMP1, SWI5, YAP5
YMR086W NO SYMBOL FKH1
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
tricarboxylic acid cycle, TCA intermediate metabolism, amino acid biosynthesis, propionate metabolism, glutamine family amino acid metabolism, carboxylic acid metabolism aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytosol, mitochondrion CIN5, YAP6
YPR145W ASN1 asparagine biosynthesis ->
amino acid biosynthesis, aspartate family amino acid metabolism asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YMR134W NO SYMBOL BAS1, CIN5, FZF1, HAP3, RCS1
Main: amino acid biosynthesis (0.40) aconitate hydratase activity (0.25) mitochondrion (0.67) RCS1 CIN5 DAL81 (0.29)
Score: 0.10 0.00 0.33 0.143
P-value: 2.105E-01 (amino acid biosynthesis) 2.414E+00 (enzyme activity) 1.630E+00 (mitochondrion) 1.146E-01 (DAL81)

CSRE(1) AND HAP234(1) => SimExpr(YLR304C) : 6

EXPR: (0.145) HAP234 (P < 0.006) CSRE (P < 0.000)

ORF SYMBOL P F C TF
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YNL069C RPL16B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YKL141W SDH3 oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways succinate dehydrogenase activity ->
succinate dehydrogenase activity respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
Main: energy pathways (0.67) RNA binding (0.17) cytoplasm (1.00) RAP1 MET4 (0.40)
Score: 0.73 0.00 1.00 0.200
P-value: 4.809E-05 (tricarboxylic acid cycle) 3.006E-02 (oxidoreductase activity) 7.682E-03 (mitochondrial electron transport chain) 5.318E-02 (MET4)

m_RPE49(1) AND PDR(1) => SimExpr(YLR304C) : 5

EXPR: (0.163) m_RPE49 (P < 0.009) PDR (P < 0.001)

ORF SYMBOL P F C TF
YGR035C NO SYMBOL CIN5, MET4, SMP1, YAP6
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YML116W ATR1 multidrug transport ->
transport, response to abiotic stimulus multidrug efflux pump activity ->
multidrug efflux pump activity plasma membrane ->
plasma membrane CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YML026C RPS18B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, SWI4, YAP5
YKL141W SDH3 oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways succinate dehydrogenase activity ->
succinate dehydrogenase activity respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
Main: energy pathways (0.50) aconitate hydratase activity (0.25) cytoplasm (0.75) YAP6 CIN5 (0.75)
Score: 0.33 0.00 0.50 0.500
P-value: 2.303E-03 (tricarboxylic acid cycle) 2.509E+00 (enzyme activity) 7.999E-01 (cytosol) 6.015E-03 (YAP6)

RAP1(1) AND PDR(1) => SimExpr(YML026C) OR SimExpr(other) : 5 1

EXPR: (0.161) RAP1 (P < 0.104) PDR (P < 0.000)

ORF SYMBOL P F C TF
|YOR213C| SAS5 chromatin silencing at telomere ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription acetyltransferase activity ->
acetyltransferase activity nuclear chromosome\, telomeric region, nuclear chromatin ->
chromosome, nuclear chromosome GRF10(Pho2), SUM1
YNL096C RPS7B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, SFP1
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
YLR441C RPS1A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, YAP5
YML026C RPS18B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, SWI4, YAP5
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
Main: biosynthesis (0.83) structural constituent of ribosome (0.50) cytoplasm (0.83) RAP1 YAP5 FHL1 (0.67)
Score: 0.67 0.20 0.67 0.600
P-value: 1.770E-02 (biosynthesis) 2.066E-02 (structural constituent of ribosome) 1.614E-03 (cytosolic small ribosomal subunit (sensu Eukarya)) 1.154E-05 (YAP5)

RAP1(1) AND m_morphogenesis_orfnum2SD_n5(1) => SimExpr(YML026C) OR SimExpr(other) : 5 2

EXPR: (0.173) RAP1 (P < 0.142) m_morphogenesis_orfnum2SD_n5 (P < 0.000)

RAP1(1) AND m_RPE69(1) => SimExpr(YML026C) : 6

EXPR: (0.096) RAP1 (P < 0.004) m_RPE69 (P < 0.005)

ALPHA1(1) AND m_phosphate_transport_orfnum2SD_n18(1) AND m_other_cation_transporters_orfnum2SD_n3(1) => SimExpr(YML116W) OR SimExpr(other) : 5 1

EXPR: (0.190) m_other_cation_transporters_orfnum2SD_n3 (P < 0.001) m_phosphate_transport_orfnum2SD_n18 (P < 0.000) ALPHA1 (P < 0.000)

m_drug_transporters_orfnum2SD_n10(1) AND m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6(1) => SimExpr(YML116W) OR SimExpr(other) : 5 2

EXPR: (0.212) m_drug_transporters_orfnum2SD_n10 (P < 0.001) m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6 (P < 0.005)

ORF SYMBOL P F C TF
YMR220W ERG8 ergosterol biosynthesis, isoprenoid biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism phosphomevalonate kinase activity ->
phosphomevalonate kinase activity cytosol ->
cytoplasm
|YKL164C| PIR1 intracellular protein transport, cell wall organization and biogenesis ->
cell organization and biogenesis, transport structural constituent of cell wall ->
structural constituent of cell wall cell wall ->
cell wall BAS1, MCM1, PHD1, SMP1, SWI5
YMR024W MRPL3 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex
YDR276C PMP3 cation transport ->
transport plasma membrane ->
plasma membrane GAT1
|YGL262W| NO SYMBOL YJL206C
YML116W ATR1 multidrug transport ->
transport, response to abiotic stimulus multidrug efflux pump activity ->
multidrug efflux pump activity plasma membrane ->
plasma membrane CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YNL208W NO SYMBOL INO2
Main: transport (0.60) structural constituent of cell wall (0.25) cytoplasm (0.40) PHD1 (0.40)
Score: 0.40 0.00 0.20 0.100
P-value: 1.245E+00 (transport) 4.947E-01 (structural molecule activity) 4.928E-01 (plasma membrane) 2.510E-01 (PHD1)

RAP1(1) AND m_pentose-phosphate_pathway_orfnum2SD_n5(1) => SimExpr(YOR096W) OR SimExpr(other) : 6 1

EXPR: (0.161) m_pentose-phosphate_pathway_orfnum2SD_n5 (P < 0.000) RAP1 (P < 0.113)

m_RPE57(1) AND m_LFTE17(1) => SimExpr(YOR096W) OR SimExpr(other) : 6 2

EXPR: (0.188) m_LFTE17 (P < 0.000) m_RPE57 (P < 0.073)

RAP1(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) => SimExpr(YOR096W) OR SimExpr(other) : 6 1

EXPR: (0.150) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.000) RAP1 (P < 0.068)

RAP1(1) AND CSRE(1) => SimExpr(YOR096W) OR SimExpr(other) : 12 2

EXPR: (0.159) RAP1 (P < 0.026) CSRE (P < 0.000)

m_RPE8(1) AND CSRE(1) => SimExpr(YOR096W) OR SimExpr(other) : 11 4

EXPR: (0.172) m_RPE8 (P < 0.004) CSRE (P < 0.000)

m_RPE57(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n8.scn(1) => SimExpr(YOR096W) OR SimExpr(other) : 6 1

EXPR: (0.155) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n8.scn (P < 0.000) m_RPE57 (P < 0.014)

m_RPE57(1) AND m_RPE8(1) => SimExpr(YOR096W) : 5

EXPR: (0.085) m_RPE8 (P < 0.000) m_RPE57 (P < 0.000)

m_pentose-phosphate_pathway_orfnum2SD_n5(1) AND m_RPE6(1) => SimExpr(YOR096W) : 6

EXPR: (0.123) m_pentose-phosphate_pathway_orfnum2SD_n5 (P < 0.000) m_RPE6 (P < 0.053)

RAP1(1) AND m_RPE6(1) => SimExpr(YOR096W) : 9

EXPR: (0.114) RAP1 (P < 0.002) m_RPE6 (P < 0.005)

RAP1(1) AND m_LFTE17(1) => SimExpr(YOR096W) : 7

EXPR: (0.108) RAP1 (P < 0.002) m_LFTE17 (P < 0.000)

RAP1(1) AND m_RPE58(1) => SimExpr(YOR096W) : 6

EXPR: (0.103) RAP1 (P < 0.004) m_RPE58 (P < 0.016)

RAP1(1) AND m_metabolism_of_energy_reserves_orfnum2SD_n8(1) => SimExpr(YOR096W) : 5

EXPR: (0.105) RAP1 (P < 0.020) m_metabolism_of_energy_reserves_orfnum2SD_n8 (P < 0.000)

m_RPE57(1) AND m_RPE6(1) => SimExpr(YOR096W) : 7

EXPR: (0.119) m_RPE57 (P < 0.000) m_RPE6 (P < 0.028)

RAP1(1) AND m_RPE57(1) => SimExpr(YOR096W) : 8

EXPR: (0.114) RAP1 (P < 0.005) m_RPE57 (P < 0.000)

m_RPE6(1) AND m_RPE8(1) => SimExpr(YOR096W) : 8

EXPR: (0.097) m_RPE8 (P < 0.000) m_RPE6 (P < 0.003)

RAP1(1) AND m_RPE8(1) => SimExpr(YOR096W) : 9

EXPR: (0.090) RAP1 (P < 0.000) m_RPE8 (P < 0.000)

m_RPE8(1) AND CSRE(1) => SimExpr(YNL162W) OR SimExpr(other) : 11 4

m_RPE8(1) AND m_RPE17(1) => SimExpr(YNL162W) : 5

EXPR: (0.102) m_RPE8 (P < 0.000) m_RPE17 (P < 0.001)

m_pentose-phosphate_pathway_orfnum2SD_n5(1) AND m_RPE6(1) => SimExpr(YNL162W) : 6

m_RPE6(1) AND m_RPE21(1) => SimExpr(YNL162W) : 5

EXPR: (0.111) m_RPE21 (P < 0.011) m_RPE6 (P < 0.039)

m_organization_of_cytoplasm_orfnum2SD_n27(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YNL162W) : 5

EXPR: (0.108) m_organization_of_cytoplasm_orfnum2SD_n27 (P < 0.173) m_amino-acid_transport_orfnum2SD_n20 (P < 0.000)

m_RPE6(1) AND m_RPE8(1) => SimExpr(YNL162W) : 8

SFF'(1) AND m_RPE21(1) => SimExpr(YML073C) OR SimExpr(other) : 9 4

EXPR: (0.193) SFF' (P < 0.000) m_RPE21 (P < 0.211)

m_RPE17(1) AND m_other_cation_transporters_orfnum2SD_n14(1) => SimExpr(YML073C) OR SimExpr(other) : 5 2

EXPR: (0.175) m_other_cation_transporters_orfnum2SD_n14 (P < 0.006) m_RPE17 (P < 0.024)

ORF SYMBOL P F C TF
YML073C RPL6A protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, YAP5
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YJR123W RPS5 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GRF10(Pho2), HSF1, MSN4, YAP1
|YGR067C| NO SYMBOL ABF1, ASH1, RGM1
|YMR165C| SMP2 aerobic respiration, plasmid maintenance ->
energy pathways, cell proliferation GAT1, MAL13, MAL33, MBP1, MSN4, NDD1, PDR1, SMP1, SWI5, YAP5
YDL185W TFP1 intron homing, vacuolar acidification, protein metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell homeostasis, protein metabolism, cell organization and biogenesis, transport hydrogen-exporting ATPase activity, endodeoxyribonuclease activity ->
hydrogen-exporting ATPase activity, endodeoxyribonuclease activity vacuolar membrane (sensu Fungi), hydrogen-transporting ATPase V1 domain ->
cytoplasm, vacuole SWI4
YDR025W RPS11A protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity ->
cell organization and biogenesis, biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1
Main: biosynthesis (0.67) structural constituent of ribosome (0.60) cytoplasm (1.00) FHL1 (0.43)
Score: 0.67 0.30 1.00 0.238
P-value: 1.911E-02 (ribosomal subunit assembly) 4.835E-02 (structural constituent of ribosome) 3.736E-02 (cytosolic ribosome (sensu Eukarya)) 1.920E-02 (FHL1)

MCM1'(1) AND m_RPE34(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YML073C) OR SimExpr(other) : 5 2

EXPR: (0.168) m_cell_death_orfnum2SD_n8 (P < 0.001) m_RPE34 (P < 0.089) MCM1' (P < 0.000)

CSRE(1) AND m_RPE34(1) => SimExpr(YML073C) OR SimExpr(other) : 8 2

EXPR: (0.145) CSRE (P < 0.000) m_RPE34 (P < 0.016)

m_LFTE17(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) => SimExpr(YML073C) OR SimExpr(other) : 6 2

EXPR: (0.187) m_tricarboxylic-acid_pathway_orfnum2SD_n3 (P < 0.002) m_LFTE17 (P < 0.000)

ORF SYMBOL P F C TF
YML073C RPL6A protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism RNA binding, structural molecule activity ->
RNA binding, structural molecule activity cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, YAP5
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YGR086C PIL1 ASH1, SWI5
|YDR281C| PHM6 PHO4, SUM1
YDR450W RPS18A protein biosynthesis ->
biosynthesis, protein metabolism structural molecule activity ->
structural molecule activity cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YPL078C ATP4 ATP synthesis coupled proton transport ->
transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane REB1, ZAP1
|YKL187C| NO SYMBOL
Main: biosynthesis (0.80) structural molecule activity (0.60) cytoplasm (1.00) RAP1 GAT3 YAP5 FHL1 (0.29)
Score: 0.60 0.30 1.00 0.048
P-value: 6.217E-03 (glutamate biosynthesis) 1.759E-01 (structural molecule activity) 4.042E-01 (mitochondrial matrix) 1.025E-01 (YAP5)

CSRE(1) AND m_RPE21(1) => SimExpr(YML073C) OR SimExpr(other) : 9 4

EXPR: (0.186) CSRE (P < 0.000) m_RPE21 (P < 0.156)

CSRE(1) AND m_c-compound_carbohydrate_transport_orfnum2SD_n23(1) => SimExpr(YML073C) : 5

EXPR: (0.126) CSRE (P < 0.000) m_c-compound_carbohydrate_transport_orfnum2SD_n23 (P < 0.001)

RAP1(1) AND m_RPE34(1) => SimExpr(YML073C) : 8

EXPR: (0.102) RAP1 (P < 0.004) m_RPE34 (P < 0.002)

RAP1(1) AND m_RPE69(1) => SimExpr(YML073C) : 6

RAP1(1) AND m_RPE17(1) => SimExpr(YML073C) : 5

EXPR: (0.078) RAP1 (P < 0.000) m_RPE17 (P < 0.000)

RAP1(1) AND m_metabolism_of_energy_reserves_orfnum2SD_n8(1) => SimExpr(YML073C) : 5

RAP1(1) AND m_LFTE17(1) => SimExpr(YML073C) : 7

RAP1(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YML073C) : 8

EXPR: (0.109) RAP1 (P < 0.003) m_cell_death_orfnum2SD_n8 (P < 0.000)

m_metal_ion_transporters_orfnum2SD_n10(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YGR035C) OR SimExpr(other) : 5 2

EXPR: (0.231) m_metal_ion_transporters_orfnum2SD_n10 (P < 0.022) m_anion_transporters_orfnum2SD_n20 (P < 0.010)

m_metal_ion_transporters_orfnum2SD_n10(1) AND m_other_cation_transporters_orfnum2SD_n3(1) => SimExpr(YGR035C) OR SimExpr(other) : 5 1

EXPR: (0.202) m_metal_ion_transporters_orfnum2SD_n10 (P < 0.004) m_other_cation_transporters_orfnum2SD_n3 (P < 0.011)

ORF SYMBOL P F C TF
|YOR245C| DGA1 lipid storage, triacylglycerol biosynthesis ->
transport, glycerol ether metabolism, biosynthesis, lipid metabolism diacylglycerol O-acyltransferase activity ->
diacylglycerol O-acyltransferase activity lipid particle ->
cytoplasm
YML116W ATR1 multidrug transport ->
transport, response to abiotic stimulus multidrug efflux pump activity ->
multidrug efflux pump activity plasma membrane ->
plasma membrane CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YIL123W SIM1 microtubule cytoskeleton organization and biogenesis ->
cell organization and biogenesis cell wall ->
cell wall DIG1, FKH2, GRF10(Pho2), MCM1, STE12, SWI4, SWI6
YOR316C COT1 cobalt ion transport, zinc ion transport, zinc ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity ->
di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity vacuole (sensu Fungi) ->
cytoplasm FKH2, INO2, INO4, NDD1, RAP1
YGR035C NO SYMBOL CIN5, MET4, SMP1, YAP6
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: transport (0.60) cobalt ion transporter activity (0.33) cytoplasm (0.50) YAP6 FKH2 (0.60)
Score: 0.40 0.00 0.17 0.800
P-value: 8.341E-01 (transport) 4.458E-01 (transporter activity) 4.731E+00 (cytoplasm) 1.171E-02 (FKH2)

m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) AND m_other_transport_facilitators_orfnum2SD_n10(1) => SimExpr(YJL158C) OR SimExpr(other) : 5 1

EXPR: (0.180) m_allantoin_and_allantoate_transporters_orfnum2SD_n6 (P < 0.001) m_other_transport_facilitators_orfnum2SD_n10 (P < 0.002)

ORF SYMBOL P F C TF
|YNL019C| NO SYMBOL
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YGR086C PIL1 ASH1, SWI5
YJL158C CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YKL122C SRP21 protein-ER targeting ->
cell organization and biogenesis, protein metabolism, transport signal sequence binding ->
signal sequence binding nucleus, signal recognition particle ->
nucleus, cytoplasm REB1
YPR041W TIF5 regulation of translational initiation, mature ribosome assembly ->
cell organization and biogenesis, biosynthesis, protein metabolism GTPase activator activity, translation initiation factor activity ->
GTPase activator activity, translation initiation factor activity cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
Main: cell organization and biogenesis (1.00) signal sequence binding (0.25) cytoplasm (1.00) REB1 (0.75)
Score: 1.00 0.00 1.00 0.500
P-value: 9.931E-03 (protein-ER targeting) 1.806E+00 (binding) 4.489E-02 (endoplasmic reticulum) 1.095E-02 (REB1)

m_RPE72(1) AND m_RPE8(1) => SimExpr(YJL158C) : 5

EXPR: (0.160) m_RPE72 (P < 0.002) m_RPE8 (P < 0.003)

m_MERE4(1) AND m_RPE8(1) => SimExpr(YJL158C) : 7

EXPR: (0.162) m_RPE8 (P < 0.000) m_MERE4 (P < 0.000)

ORF SYMBOL P F C TF
YNL162W RPL42A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1, YAP5
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
YMR292W GOT1 ER to Golgi transport, Golgi to endosome transport ->
cell organization and biogenesis, transport, vesicle-mediated transport Golgi membrane ->
cytoplasm, endomembrane system MSS11
YIL069C RPS24B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, INO2, MCM1, RAP1
YJL158C CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YDR086C SSS1 cotranslational membrane targeting ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity translocon ->
cytoplasm HIR1, IXR1, MIG1, RFX1, SIP4
YNL231C PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
Main: biosynthesis (0.57) structural constituent of ribosome (0.33) cytoplasm (1.00) SWI4 RAP1 FHL1 (0.33)
Score: 0.67 0.07 1.00 0.133
P-value: 5.525E-01 (alcohol metabolism) 1.488E-01 (structural molecule activity) 4.171E-01 (cytosolic ribosome (sensu Eukarya)) 3.841E-01 (FHL1)

SFF'(1) AND m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n12(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YOR022C) OR SimExpr(other) : 6 1

EXPR: (0.202) SFF' (P < 0.000) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n12 (P < 0.000)

ORF SYMBOL P F C TF
YOR022C NO SYMBOL
|YNL162W| RPL42A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1, YAP5
YMR250W GAD1 response to oxidative stress, glutamate catabolism ->
response to oxidative stress, glutamate catabolism glutamate decarboxylase activity ->
glutamate decarboxylase activity cytoplasm ->
cytoplasm
YJL082W IML2
YPR124W CTR1 protein biosynthesis, copper ion import ->
protein biosynthesis, copper ion import copper uptake transporter activity ->
copper uptake transporter activity plasma membrane ->
plasma membrane CIN5, INO2, INO4, MAC1, SMP1
YJL005W CYR1 meiosis, G-protein signaling\, coupled to cAMP nucleotide second messenger, RAS protein signal transduction, regulation of cell cycle ->
meiosis, G-protein signaling\, coupled to cAMP nucleotide second messenger, RAS protein signal transduction, regulation of cell cycle adenylate cyclase activity ->
adenylate cyclase activity plasma membrane ->
plasma membrane
YHL043W ECM34 cell wall organization and biogenesis ->
cell wall organization and biogenesis
Main: protein biosynthesis (0.40) glutamate decarboxylase activity (0.25) cytoplasm (0.50) INO2 (0.50)
Score: 0.10 0.00 0.33 0.000
P-value: 1.916E+00 (protein biosynthesis) 8.699E-02 (lyase activity) 4.928E-01 (plasma membrane) 8.282E-01 (INO2)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_anion_transporters_orfnum2SD_n4(1) AND CSRE(1) => SimExpr(YNL098C) OR SimExpr(other) : 6 2

EXPR: (0.229) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.002) CSRE (P < 0.000) m_anion_transporters_orfnum2SD_n4 (P < 0.005)

STRE'(1) AND m_cell_rescue_defense_cell_death_and_ageing_orfnum2SD_n20(1) => SimExpr(YNL098C) OR SimExpr(other) : 7 1

EXPR: (0.193) m_cell_rescue_defense_cell_death_and_ageing_orfnum2SD_n20 (P < 0.005) STRE' (P < 0.000)

ORF SYMBOL P F C TF
YKL142W MRP8 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YFL039C ACT1 cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter ->
transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex ->
cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex DIG1, ROX1, STE12
YLR205C HMX1 iron ion homeostasis ->
cell homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
|YMR291W| NO SYMBOL RAP1
YPL203W TPK2 protein amino acid phosphorylation, pseudohyphal growth, RAS protein signal transduction ->
phosphorus metabolism, cell organization and biogenesis, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
membrane ACE2, SKN7
Main: cell organization and biogenesis (0.43) phosphopyruvate hydratase activity (0.14) cytoplasm (0.71) SKN7 (0.57)
Score: 0.33 0.00 0.52 0.333
P-value: 2.431E-02 (RAS protein signal transduction) 7.298E-01 (oxidoreductase activity) 3.201E+00 (cytoplasm) 2.619E-03 (SKN7)

m_detoxificaton_orfnum2SD_n39(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YNL098C) : 5

EXPR: (0.172) m_detoxificaton_orfnum2SD_n39 (P < 0.000) m_cell_death_orfnum2SD_n8 (P < 0.000)

m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n13(1) AND STRE'(1) => SimExpr(YKL035W) OR SimExpr(other) : 5 2

EXPR: (0.192) m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n13 (P < 0.001) STRE' (P < 0.000)

ORF SYMBOL P F C TF
YOL012C HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
|YOR374W| ALD4 ethanol metabolism ->
alcohol metabolism aldehyde dehydrogenase (NAD+) activity ->
aldehyde dehydrogenase (NAD+) activity mitochondrion ->
cytoplasm RAP1
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YMR291W NO SYMBOL RAP1
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
amine metabolism, alcohol metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity mitochondrion ->
cytoplasm
|YIR016W| NO SYMBOL DAL82, RAP1
Main: alcohol metabolism (0.60) chromatin binding (0.20) cytoplasm (0.75) RAP1 (0.60)
Score: 0.50 0.00 0.50 0.300
P-value: 2.268E-02 (alcohol metabolism) 1.225E+00 (transferase activity) 1.397E+00 (mitochondrion) 2.546E-02 (RAP1)

Leu3(1) AND SCB(1) => SimExpr(YJR016C) OR SimExpr(other) : 6 2

EXPR: (0.198) Leu3 (P < 0.055) SCB (P < 0.000)

m_amino-acid_metabolism_orfnum2SD_n25(1) AND Leu3(1) => SimExpr(YJR016C) OR SimExpr(other) : 5 1

EXPR: (0.164) m_amino-acid_metabolism_orfnum2SD_n25 (P < 0.001) Leu3 (P < 0.014)

ORF SYMBOL P F C TF
|YPL084W| BRO1 signal transduction, vacuolar transport, ubiquitin-dependent protein catabolism ->
signal transduction, cell organization and biogenesis, catabolism, transport, protein metabolism intracellular transporter activity ->
intracellular transporter activity cytoplasm, endosome ->
cytoplasm HAA1
YPL020C ULP1 G2/M transition of mitotic cell cycle, protein desumoylation ->
cell proliferation, protein metabolism cysteine-type peptidase activity, SUMO-specific protease activity ->
cysteine-type peptidase activity, SUMO-specific protease activity nuclear membrane, nuclear pore ->
nucleus, integral to membrane, endomembrane system ADR1
YJR016C ILV3 branched chain family amino acid biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis dihydroxy-acid dehydratase activity ->
dihydroxy-acid dehydratase activity mitochondrion ->
cytoplasm
YMR122C NO SYMBOL SWI5
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
ketol-acid reductoisomerase activity mitochondrion ->
cytoplasm GCN4, MET4
YMR108W ILV2 branched chain family amino acid biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis acetolactate synthase activity ->
acetolactate synthase activity mitochondrion ->
cytoplasm HSF1, LEU3
Main: biosynthesis (0.60) acetolactate synthase activity (0.20) cytoplasm (0.80) HSF1 (0.20)
Score: 0.50 0.00 0.60 0.000
P-value: 3.562E-05 (branched chain family amino acid biosynthesis) 6.351E-02 (lyase activity) 1.995E-01 (mitochondrion) 1.805E-02 (HAA1)

STRE'(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YJL164C) OR SimExpr(other) : 8 2

EXPR: (0.208) m_amino-acid_transport_orfnum2SD_n14 (P < 0.003) STRE' (P < 0.020)

ORF SYMBOL P F C TF
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
cell organization and biogenesis, phosphorus metabolism, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
phosphotransferase activity\, alcohol group as acceptor cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
hydro-lyase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
|YOL012C| HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
|YFL039C| ACT1 cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter ->
transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex ->
cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex DIG1, ROX1, STE12
YLR205C HMX1 iron ion homeostasis ->
cell homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, miscellaneous membrane ->
membrane MAL13, PHO4, SKN7
YOR374W ALD4 ethanol metabolism ->
alcohol metabolism aldehyde dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor mitochondrion ->
cytoplasm RAP1
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in linear amidines cytosol ->
cytoplasm GCN4
YDR381W YRA1 mRNA-nucleus export ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding transcription export complex ->
nucleus ARO80
Main: cell organization and biogenesis (0.30) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.20) cytoplasm (0.70) SKN7 PHO4 FKH2 SWI5 IME4 (0.20)
Score: 0.29 0.02 0.53 0.067
P-value: 5.321E-02 (main pathways of carbohydrate metabolism) 3.907E-02 (oxidoreductase activity) 1.314E+00 (nucleoplasm) 1.122E-01 (IME4)

m_nutritional_response_pathway_orfnum2SD_n7(1) AND STRE'(1) => SimExpr(YJL164C) OR SimExpr(other) : 6 1

EXPR: (0.196) m_nutritional_response_pathway_orfnum2SD_n7 (P < 0.000) STRE' (P < 0.020)

ORF SYMBOL P F C TF
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YDR511W ACN9 carbon utilization by utilization of organic compounds, gluconeogenesis ->
carbon utilization by utilization of organic compounds, gluconeogenesis mitochondrial intermembrane space ->
cytoplasm MBP1, STB1
YPL111W CAR1 arginine catabolism to ornithine ->
arginine catabolism to ornithine arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
|YGL215W| CLG1 cell cycle ->
cell cycle cyclin-dependent protein kinase\, regulator activity ->
protein serine/threonine kinase activity, protein kinase regulator activity cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex
YAL061W NO SYMBOL
YML117W NAB6
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction RAS small monomeric GTPase activity ->
GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
Main: pseudohyphal growth (0.40) protein serine/threonine kinase activity (0.50) cytoplasm (0.60) ACE2 (0.25)
Score: 0.10 0.17 0.30 0.000
P-value: 8.659E-03 (RAS protein signal transduction) 2.083E-01 (protein serine/threonine kinase activity) 4.385E+00 (cytoplasm) 6.086E-01 (SFL1)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YJL164C) OR SimExpr(other) : 10 3

EXPR: (0.220) m_cell_death_orfnum2SD_n8 (P < 0.002) m_other_signal-transduction_activities_orfnum2SD_n8 (P < 0.001)

ORF SYMBOL P F C TF
YLR362W STE11 protein amino acid phosphorylation, pseudohyphal growth, signal transduction during conjugation with cellular fusion ->
phosphorus metabolism, cell organization and biogenesis, signal transduction, conjugation, protein metabolism, perception of external stimulus, sexual reproduction, response to abiotic stimulus MAP kinase kinase kinase activity ->
protein kinase activity cytoplasm ->
cytoplasm HIR1
|YNL080C| NO SYMBOL GRF10(Pho2), INO4
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
cell organization and biogenesis, phosphorus metabolism, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid-polyamine transporter activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YAR042W SWH1 SUM1
YPL109C NO SYMBOL
|YDR134C| NO SYMBOL ASH1, NRG1, SOK2, SWI4
YIL048W NEO1 intracellular protein transport ->
transport calcium-transporting ATPase activity, phospholipid-translocating ATPase activity ->
ATP binding, aminophospholipid transporter activity, calcium ion transporter activity, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides ABF1, GLN3, UGA3
YKL167C MRP49 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex ABF1, IME4, IXR1
|YPR165W| RHO1 cell wall organization and biogenesis, bud growth, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
asexual reproduction, signal transduction, cell organization and biogenesis Rho small monomeric GTPase activity, signal transducer activity ->
GTP binding, signal transducer activity, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides 1\,3-beta-glucan synthase complex, bud tip, bud neck, shmoo tip ->
plasma membrane, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces) ABF1
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
protein kinase activity MTH1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane ACE2, SKN7
Main: cell organization and biogenesis (0.44) protein kinase activity (0.33) cytoplasm (0.57) ABF1 (0.25)
Score: 0.36 0.17 0.43 0.106
P-value: 3.459E-02 (pseudohyphal growth) 1.763E-01 (protein serine/threonine kinase activity) 3.275E-01 (plasma membrane) 1.774E-01 (IME4)

ALPHA1'(1) AND m_rRSE10(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YJL164C) : 5

EXPR: (0.162) m_rRSE10 (P < 0.001) m_cell_death_orfnum2SD_n8 (P < 0.000) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YLR346C NO SYMBOL DAL82, IME4, SWI5
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YIR038C GTT1 glutathione metabolism ->
glutathione metabolism glutathione transferase activity ->
glutathione transferase activity endoplasmic reticulum ->
cytoplasm
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
Main: pseudohyphal growth (0.50) RAS small monomeric GTPase activity (0.25) cytoplasm (0.75) DAL82 (0.25)
Score: 0.17 0.00 0.50 0.000
P-value: 4.145E-03 (RAS protein signal transduction) 7.188E-01 (transferase activity) 3.185E+00 (cytoplasm) 3.879E-01 (IME4)

ALPHA1(1) AND MCB(1) => SimExpr(YGR189C) OR SimExpr(other) : 24 8

EXPR: (0.223) ALPHA1 (P < 0.000) MCB (P < 0.020)

MCB(1) AND m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) => SimExpr(YGR189C) OR SimExpr(other) : 5 2

EXPR: (0.192) m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5 (P < 0.001) MCB (P < 0.017)

ORF SYMBOL P F C TF
YML012W ERV25 ER to Golgi transport ->
intracellular transport, secretory pathway, vesicle-mediated transport COPII-coated vesicle ->
cytoplasm ABF1
YNL082W PMS1 mismatch repair, meiosis ->
DNA repair, cell cycle, DNA metabolism ATPase activity, ATP binding, DNA binding ->
ATPase activity, ATP binding, DNA binding nuclear chromosome ->
chromosome, nucleus MTH1
YGR189C CRH1 cell wall, incipient bud site ->
cell wall, incipient bud site GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YDR097C MSH6 mismatch repair ->
DNA metabolism, cell cycle ATPase activity, ATP binding, DNA binding ->
ATPase activity, ATP binding, DNA binding nucleus ->
nucleus DOT6, MBP1, SWI6
YNL206C RTT106 negative regulation of DNA transposition ->
DNA metabolism MSS11, SIP4, SUM1
|YJR043C| POL32 leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, mismatch repair, postreplication repair ->
cell cycle, DNA metabolism, S phase of mitotic cell cycle delta DNA polymerase activity ->
delta DNA polymerase activity delta DNA polymerase complex, nucleus ->
cytoplasm, nucleus MOT3, RTS2
|YNL088W| TOP2 negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, meiotic recombination ->
nuclear organization and biogenesis, negative regulation of DNA recombination, cell cycle, DNA metabolism, DNA packaging DNA topoisomerase type II activity ->
DNA topoisomerase type II activity nucleus, synaptonemal complex ->
nucleus, chromosome MBP1, SWI6
Main: DNA metabolism (0.83) DNA binding (0.50) nucleus (0.67) MBP1 (0.43)
Score: 0.67 0.17 0.47 0.143
P-value: 4.479E-05 (maintenance of fidelity during DNA dependent DNA replication) 5.733E-01 (ATPase activity) 1.949E-01 (chromosome) 1.421E-02 (MBP1)

MCB(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n8(1) => SimExpr(YGR189C) OR SimExpr(other) : 5 2

EXPR: (0.180) m_deoxyribonucleotide_metabolism_orfnum2SD_n8 (P < 0.000) MCB (P < 0.008)

ORF SYMBOL P F C TF
|YLR212C| TUB4 microtubule nucleation, mitotic spindle assembly (sensu Saccharomyces) ->
cell organization and biogenesis, cell proliferation, cell cycle structural constituent of cytoskeleton ->
structural constituent of cytoskeleton inner plaque of spindle pole body, outer plaque of spindle pole body ->
cytoplasm
YIL026C IRR1 mitotic sister chromatid cohesion, colony morphology, germination (sensu Saccharomyces), cytogamy ->
cell organization and biogenesis, sporulation, plasma membrane fusion, sporulation (sensu Fungi), cell proliferation, conjugation, sexual reproduction protein binding ->
protein binding nuclear cohesin complex ->
chromosome, nucleus ABF1, MAL33, MBP1, SWI6
YFR027W ECO1 sister chromatid cohesion, DNA replication, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation acetyltransferase activity ->
acetyltransferase activity nuclear chromatin ->
chromosome, nucleus
YNL039W BDP1 transcription initiation from Pol III promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase III transcription factor activity ->
RNA polymerase III transcription factor activity transcription factor TFIIIB complex ->
nucleus
YGR189C CRH1 cell wall, incipient bud site ->
cell wall, incipient bud site GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YKL042W SPC42 microtubule nucleation, spindle pole body duplication (sensu Saccharomyces) ->
cell organization and biogenesis, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton intermediate layer of spindle pole body, central plaque of spindle pole body ->
cytoplasm
|YIL066C| RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity cytoplasm ->
cytoplasm RFX1, STB1
Main: cell proliferation (0.83) structural constituent of cytoskeleton (0.33) cytoplasm (0.43) MBP1 (0.67)
Score: 0.80 0.07 0.29 0.333
P-value: 3.752E-04 (DNA replication and chromosome cycle) 2.692E-02 (structural constituent of cytoskeleton) 9.987E-02 (spindle pole body) 2.025E-01 (MBP1)

m_osmosensing_orfnum2SD_n6(1) AND MCB(1) => SimExpr(YGR189C) OR SimExpr(other) : 6 2

EXPR: (0.218) m_osmosensing_orfnum2SD_n6 (P < 0.000) MCB (P < 0.090)

ORF SYMBOL P F C TF
YMR179W SPT21 regulation of transcription from Pol II promoter ->
transcription MBP1, STB1, SWI4, SWI6, UGA3
YGR189C CRH1 cell wall, incipient bud site ->
cell wall, incipient bud site GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YGR085C RPL11B protein biosynthesis, ribosomal large subunit assembly and maintenance ->
macromolecule biosynthesis, cytoplasm organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MIG1
YPR007C SPO69 meiosis, sister chromatid cohesion ->
cell cycle binding ->
binding condensed nuclear chromosome\, pericentric region, nuclear cohesin complex ->
chromosome, nuclear chromosome MCM1
|YIL066C| RNR3 DNA replication ->
cell cycle, DNA metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity cytoplasm ->
cytoplasm RFX1, STB1
YJL181W NO SYMBOL
|YNL012W| SPO1 meiosis ->
cell cycle phospholipase activity ->
phospholipase activity nucleus ->
nucleus ARO80, SRD1
YML027W YOX1 negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
regulation of transcription, M phase, transcription, cell cycle specific transcriptional repressor activity, binding ->
specific transcriptional repressor activity, binding nucleus ->
nucleus MBP1, SWI4, SWI6
Main: cell cycle (0.67) binding (0.40) cytoplasm (0.33) SWI4 MBP1 (0.43)
Score: 0.47 0.10 0.13 0.190
P-value: 1.756E-01 (nuclear division) 3.060E+00 (binding) 3.467E+00 (nucleus) 2.223E-02 (MBP1)

MCB(1) AND m_nutritional_response_pathway_orfnum2SD_n7(1) => SimExpr(YGR189C) OR SimExpr(other) : 7 1

EXPR: (0.201) m_nutritional_response_pathway_orfnum2SD_n7 (P < 0.000) MCB (P < 0.026)

ORF SYMBOL P F C TF
YOR343C NO SYMBOL DIG1, RAP1, STE12
YJR030C NO SYMBOL MBP1, PHO4, RTG1, SWI6
|YNR028W| CPR8 peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity ASH1, DIG1, MCM1
YGL163C RAD54 double-strand break repair via synthesis-dependent strand annealing, heteroduplex formation, double-strand break repair via break-induced replication, telomerase-independent telomere maintenance, double-strand break repair via single-strand annealing, chromatin modeling ->
mating-type switching/recombination, chromosome organization and biogenesis (sensu Eukarya), DNA repair, response to DNA damage, DNA metabolism DNA supercoiling activity, DNA dependent ATPase activity ->
DNA supercoiling activity, DNA dependent ATPase activity nucleus ->
nucleus
YGR189C CRH1 cell wall, incipient bud site ->
cell wall, incipient bud site GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YNL233W BNI4 cytokinesis ->
cytokinesis protein binding ->
protein binding contractile ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoplasm PHO4
YGR085C RPL11B protein biosynthesis, ribosomal large subunit assembly and maintenance ->
macromolecule biosynthesis, cytoplasm organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MIG1
YIL140W AXL2 axial budding, bud site selection ->
budding, cytokinesis, cytoplasm organization and biogenesis integral to plasma membrane, bud, bud neck, septin ring ->
integral to membrane, bud, site of polarized growth (sensu Fungi), cell cortex, plasma membrane STB1, SWI4
Main: cytoplasm organization and biogenesis (0.50) peptidyl-prolyl cis-trans isomerase activity (0.25) cell cortex (0.40) SWI4 PHO4 MBP1 DIG1 STE12 (0.29)
Score: 0.33 0.00 0.20 0.238
P-value: 1.033E-01 (cytokinesis) 3.060E+00 (binding) 1.457E-01 (bud neck) 1.038E-01 (DIG1)

ALPHA1(1) AND MCB(1) AND m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) => SimExpr(YGR189C) : 5

EXPR: (0.151) m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5 (P < 0.000) ALPHA1 (P < 0.000) MCB (P < 0.000)

m_nutritional_response_pathway_orfnum2SD_n7(1) AND m_anion_transporters_orfnum2SD_n17(1) => SimExpr(YPR138C) OR SimExpr(other) : 11 4

EXPR: (0.237) m_nutritional_response_pathway_orfnum2SD_n7 (P < 0.001) m_anion_transporters_orfnum2SD_n17 (P < 0.008)

ORF SYMBOL P F C TF
YDL130W RPP1B protein biosynthesis, translational elongation ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAL4, RAP1, RFX1
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
transporter activity plasma membrane ->
plasma membrane SWI5
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
|YHR178W| STB5 response to xenobiotic stimulus ->
response to abiotic stimulus transcription factor activity ->
DNA binding nucleus ->
nucleus
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
oxidoreductase activity\, acting on diphenols and related substances as donors, transporter activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
|YNL233W| BNI4 cytokinesis ->
cell proliferation protein binding ->
protein binding contractile ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoplasm PHO4
YPR138C MEP3 ammonium transport ->
transport ammonium transporter activity ->
transporter activity plasma membrane ->
plasma membrane
YKL193C SDS22 protein targeting, chromosome segregation ->
cell proliferation, protein metabolism, transport enzyme regulator activity, protein phosphatase type 1\, regulator activity ->
enzyme regulator activity, hydrolase activity\, acting on ester bonds cytoplasm, nucleus ->
cytoplasm, nucleus
YKL152C GPM1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphoglycerate mutase activity ->
intramolecular transferase activity cytosol ->
cytoplasm GCR1, GCR2, HSF1, RAP1
YDR276C PMP3 cation transport ->
transport plasma membrane ->
plasma membrane GAT1
YIL088C AVT7 transport ->
transport transporter activity ->
transporter activity vacuole ->
cytoplasm CBF1, SIP4
|YIL125W| KGD1 tricarboxylic acid cycle, 2-oxoglutarate metabolism ->
carbohydrate metabolism, ketone metabolism, organic acid metabolism, energy pathways oxoglutarate dehydrogenase (lipoamide) activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors mitochondrial matrix ->
cytoplasm REB1, UGA3
YMR086W NO SYMBOL FKH1
YNR045W PET494 protein biosynthesis ->
biosynthesis, protein metabolism translation regulator activity ->
translation regulator activity mitochondrial inner membrane ->
cytoplasm, inner membrane
|YPL221W| BOP1 CBF1
Main: transport (0.38) transporter activity (0.33) cytoplasm (0.69) CBF1 RAP1 (0.18)
Score: 0.28 0.11 0.51 0.036
P-value: 6.021E-01 (energy pathways) 8.916E-01 (cation transporter activity) 8.571E-01 (cytosolic large ribosomal subunit (sensu Eukarya)) 2.737E-01 (CBF1)

SFF(1) AND ALPHA1'(1) AND m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9(1) => SimExpr(YPL111W) OR SimExpr(other) : 11 5

EXPR: (0.249) SFF (P < 0.000) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9 (P < 0.083) ALPHA1' (P < 0.001)

ORF SYMBOL P F C TF
YIL121W QDR2 PHO4, RAP1, SWI4
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
carbon-oxygen lyase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
|YMR181C| NO SYMBOL
YOL087C NO SYMBOL DAL82
|YNL068C| FKH2 G2-specific transcription in mitotic cell cycle, pseudohyphal growth, regulation of cell cycle ->
cell organization and biogenesis, cell proliferation, transcription transcription factor activity ->
DNA binding nucleus ->
nucleus FHL1, RAP1
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups
YOR374W ALD4 ethanol metabolism ->
alcohol metabolism aldehyde dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors mitochondrion ->
cytoplasm RAP1
|YMR199W| CLN1 regulation of CDK activity ->
cell proliferation cyclin-dependent protein kinase\, regulator activity ->
transferase activity\, transferring phosphorus-containing groups, protein kinase regulator activity nucleus, cytoplasm ->
nucleus, cytoplasm FKH2, MBP1, NDD1, SKN7, STE12, SWI4, SWI6
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds cytosol ->
cytoplasm GCN4
|YGR116W| SPT6 establishment and/or maintenance of chromatin architecture, regulation of transcription\, DNA-dependent, nucleosome assembly, RNA elongation from Pol II promoter ->
cell organization and biogenesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism Pol II transcription elongation factor activity ->
Pol II transcription elongation factor activity nucleus, transcription elongation factor complex ->
nucleus CBF1, MSS11, RGT1, SIG1, SOK2
YAL061W NO SYMBOL
YIL045W PIG2 protein phosphatase regulator activity ->
protein phosphatase regulator activity CIN5
YDR100W TVP15 RAP1
|YPR015C| NO SYMBOL
YJL057C NO SYMBOL SRD1
YIL124W AYR1 phosphatidic acid biosynthesis ->
biosynthesis, membrane lipid metabolism, organic acid metabolism, lipid metabolism acylglycerone-phosphate reductase activity ->
oxidoreductase activity\, acting on CH-OH group of donors endoplasmic reticulum, lipid particle, cytoplasm ->
cytoplasm
Main: alcohol metabolism (0.38) transferase activity\, transferring phosphorus-containing groups (0.22) cytoplasm (0.71) RAP1 (0.36)
Score: 0.36 0.03 0.62 0.145
P-value: 7.168E-01 (alcohol metabolism) 1.043E+00 (enzyme regulator activity) 3.867E+00 (cytosol) 3.052E-01 (RAP1)

m_amino-acid_transport_orfnum2SD_n3(1) AND MIG1(1) => SimExpr(YPL111W) OR SimExpr(other) : 5 2

EXPR: (0.213) MIG1 (P < 0.007) m_amino-acid_transport_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
|YMR122C| NO SYMBOL SWI5
YAL039C CYC3 cytochrome c-heme linkage ->
cytochrome c-heme linkage holocytochrome c synthase activity ->
holocytochrome c synthase activity mitochondrial intermembrane space ->
cytoplasm
YGR121C MEP1 ammonium transport ->
ammonium transport ammonium transporter activity ->
ammonium transporter activity plasma membrane ->
plasma membrane CIN5
|YMR003W| NO SYMBOL
YGR086C PIL1 ASH1, SWI5
YPL111W CAR1 arginine catabolism to ornithine ->
arginine catabolism to ornithine arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YGL062W PYC1 NADPH regeneration, gluconeogenesis ->
NADPH regeneration, gluconeogenesis pyruvate carboxylase activity ->
pyruvate carboxylase activity cytosol ->
cytoplasm DIG1, GCR1, STE12
Main: ammonium transport (0.25) pyruvate carboxylase activity (0.25) cytoplasm (0.75) SWI5 (0.40)
Score: 0.00 0.00 0.50 0.100
P-value: 3.852E+00 (metabolism) 2.414E+00 (enzyme activity) 1.086E+00 (cytosol) 7.212E-02 (SWI5)

m_intracellular_communication_orfnum2SD_n10(1) AND m_pentose-phosphate_pathway_orfnum2SD_n23(1) => SimExpr(YPL111W) OR SimExpr(other) : 5 1

EXPR: (0.193) m_pentose-phosphate_pathway_orfnum2SD_n23 (P < 0.000) m_intracellular_communication_orfnum2SD_n10 (P < 0.005)

ORF SYMBOL P F C TF
|YNL241C| ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YMR139W RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
transferase activity\, transferring phosphorus-containing groups MAL33, YJL206C
YAL039C CYC3 cytochrome c-heme linkage ->
protein metabolism holocytochrome c synthase activity ->
carbon-sulfur lyase activity mitochondrial intermembrane space ->
cytoplasm
YPR138C MEP3 ammonium transport ->
transport ammonium transporter activity ->
cation transporter activity plasma membrane ->
plasma membrane
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds cytosol ->
cytoplasm GCN4
Main: protein metabolism (0.50) transferase activity\, transferring phosphorus-containing groups (0.33) cytoplasm (0.75) ACE2 (0.33)
Score: 0.47 0.07 0.50 0.000
P-value: 8.710E-02 (glucose metabolism) 4.265E-01 (transferase activity\, transferring phosphorus-containing groups) 3.918E+00 (cytoplasm) 4.587E-01 (ADR1)

m_ion_transporters_orfnum2SD_n3(1) AND m_amino-acid_transporters_orfnum2SD_n11(1) => SimExpr(YJL157C) OR SimExpr(other) : 6 2

EXPR: (0.198) m_amino-acid_transporters_orfnum2SD_n11 (P < 0.000) m_ion_transporters_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
carboxylic acid transporter activity, polyamine transporter activity, electrochemical potential-driven transporter activity plasma membrane ->
plasma membrane SWI5
YJL157C FAR1 signal transduction during conjugation with cellular fusion, cell cycle arrest ->
signal transduction, cell proliferation, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus cyclin-dependent protein kinase inhibitor activity ->
kinase inhibitor activity cytoplasm, nucleus ->
cytoplasm, nucleus MCM1
YPR138C MEP3 ammonium transport ->
transport ammonium transporter activity ->
cation transporter activity plasma membrane ->
plasma membrane
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
purine nucleotide binding, multidrug transporter activity, primary active transporter activity, hydrolase activity\, acting on acid anhydrides plasma membrane ->
plasma membrane
YOL122C SMF1 manganese ion transport ->
transport manganese ion transporter activity ->
cation transporter activity, metal ion transporter activity plasma membrane, vacuole (sensu Fungi) ->
plasma membrane, cytoplasm
YJL171C NO SYMBOL CIN5, MTH1
|YIL066C| RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
oxidoreductase activity\, acting on CH2 groups cytoplasm ->
cytoplasm RFX1, STB1
|YPR115W| NO SYMBOL IME4, INO4, UGA3
Main: transport (0.67) cation transporter activity (0.33) plasma membrane (0.67) MTH1 (0.20)
Score: 0.53 0.07 0.60 0.000
P-value: 1.521E-01 (cation transport) 6.034E-02 (transporter activity) 6.598E-03 (plasma membrane) 6.885E-01 (IME4)

m_deoxyribonucleotide_metabolism_orfnum2SD_n10(1) AND ECB(1) => SimExpr(YJL157C) OR SimExpr(other) : 10 3

EXPR: (0.218) ECB (P < 0.000) m_deoxyribonucleotide_metabolism_orfnum2SD_n10 (P < 0.000)

ORF SYMBOL P F C TF
YKR042W UTH1 mitochondrion organization and biogenesis ->
cell organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
YIL168W SDL1 serine family amino acid metabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism L-serine ammonia-lyase activity ->
L-serine ammonia-lyase activity
YOR086C NO SYMBOL ABF1, STE12
|YPL195W| APL5 Golgi to vacuole transport ->
cell organization and biogenesis, transport, vesicle-mediated transport AP-3 adaptor complex ->
cytoplasm SWI5
|YMR122C| NO SYMBOL SWI5
YJL157C FAR1 signal transduction during conjugation with cellular fusion, cell cycle arrest ->
signal transduction, cell proliferation, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus cyclin-dependent protein kinase inhibitor activity ->
cyclin-dependent protein kinase inhibitor activity cytoplasm, nucleus ->
cytoplasm, nucleus MCM1
YKL080W VMA5 vacuolar acidification ->
cell homeostasis, cell organization and biogenesis, transport hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole
YPR161C SGV1 transcription, protein amino acid phosphorylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, phosphorus metabolism, protein metabolism cyclin-dependent protein kinase activity ->
cyclin-dependent protein kinase activity nucleus ->
nucleus RAP1
YKR091W SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm DIG1, RLM1, STE12
YIL069C RPS24B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, INO2, MCM1, RAP1
|YPL159C| NO SYMBOL ABF1, UGA3
YNL138W SRV2 cytoskeleton organization and biogenesis, RAS protein signal transduction ->
cell organization and biogenesis, signal transduction cytoskeletal protein binding, adenylate cyclase binding ->
cytoskeletal protein binding, adenylate cyclase binding actin cortical patch (sensu Saccharomyces) ->
cell cortex, cytoplasm ABF1
YMR253C NO SYMBOL MCM1
Main: cell organization and biogenesis (0.44) L-serine ammonia-lyase activity (0.20) cytoplasm (0.88) MCM1 (0.36)
Score: 0.25 0.00 0.79 0.255
P-value: 9.448E-02 (vacuolar transport) 2.997E+00 (enzyme activity) 4.962E+00 (cytoplasm) 1.255E-02 (MCM1)

RAP1(1) AND m_homeostasis_of_metal_ions_orfnum2SD_n20(1) => SimExpr(YJR145C) OR SimExpr(other) : 5 1

EXPR: (0.203) m_homeostasis_of_metal_ions_orfnum2SD_n20 (P < 0.001) RAP1 (P < 0.036)

RAP1(1) AND m_metabolism_of_energy_reserves_orfnum2SD_n8(1) => SimExpr(YJR145C) : 5

RAP1(1) AND m_RPE58(1) => SimExpr(YJR145C) : 6

RAP1(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YJR145C) : 8

RAP1(1) AND m_RPE57(1) => SimExpr(YJR145C) : 8

m_g-proteins_orfnum2SD_n11(1) AND m_peroxisomal_transport_orfnum2SD_n19(1) => SimExpr(YAL022C) OR SimExpr(other) : 7 1

EXPR: (0.211) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_peroxisomal_transport_orfnum2SD_n19 (P < 0.008)

ORF SYMBOL P F C TF
YAL060W BDH1 butanediol fermentation ->
energy pathways (R\,R)-butanediol dehydrogenase activity ->
(R\,R)-butanediol dehydrogenase activity cytoplasm ->
intracellular
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
intracellular CIN5, YAP6
YNR035C ARC35 cell growth and/or maintenance ->
cell growth and/or maintenance structural molecule activity ->
structural molecule activity Arp2/3 protein complex ->
intracellular ABF1
|YMR170C| ALD2 beta-alanine biosynthesis, aldehyde metabolism, polyamine catabolism ->
aldehyde metabolism, amine metabolism, amino acid derivative catabolism, secondary metabolism, organic acid metabolism, amino acid and derivative metabolism, biosynthesis, catabolism aldehyde dehydrogenase activity ->
aldehyde dehydrogenase activity cytoplasm ->
intracellular GRF10(Pho2)
YAL022C FUN26 nucleoside transport ->
cell growth and/or maintenance nucleoside transporter activity ->
nucleoside transporter activity intracellular, membrane ->
intracellular, membrane ADR1, FHL1, FZF1, IME4, MAC1, MATa1, NRG1, PDR1, SFP1, SMP1, STB1, SWI5, YFL044C
YOL122C SMF1 manganese ion transport ->
cell growth and/or maintenance manganese ion transporter activity ->
manganese ion transporter activity plasma membrane, vacuole (sensu Fungi) ->
membrane, intracellular
YKL170W MRPL38 protein biosynthesis ->
biosynthesis, protein metabolism structural molecule activity ->
structural molecule activity mitochondrial large ribosomal subunit ->
intracellular FKH1
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity CRZ1
Main: biosynthesis (0.50) structural molecule activity (0.25) intracellular (1.00) ABF1 (0.17)
Score: 0.36 0.04 1.00 0.000
P-value: 1.215E-02 (biogenic amine metabolism) 1.986E-01 (lyase activity) 2.939E-01 (mitochondrial matrix) 7.710E-01 (ADR1)

m_homeostasis_of_metal_ions_orfnum2SD_n20(1) AND m_other_cation_transporters_orfnum2SD_n3(1) => SimExpr(YOR153W) OR SimExpr(other) : 7 2

EXPR: (0.219) m_homeostasis_of_metal_ions_orfnum2SD_n20 (P < 0.010) m_other_cation_transporters_orfnum2SD_n3 (P < 0.013)

m_homeostasis_of_metal_ions_orfnum2SD_n20(1) AND m_other_mrna-transcription_activities_orfnum2SD_n20(1) => SimExpr(YOR153W) OR SimExpr(other) : 7 3

EXPR: (0.238) m_other_mrna-transcription_activities_orfnum2SD_n20 (P < 0.014) m_homeostasis_of_metal_ions_orfnum2SD_n20 (P < 0.035)

m_other_transport_facilitators_orfnum2SD_n10(1) AND BAS1(1) => SimExpr(YOR153W) OR SimExpr(other) : 6 1

EXPR: (0.202) m_other_transport_facilitators_orfnum2SD_n10 (P < 0.012) BAS1 (P < 0.002)

ORF SYMBOL P F C TF
|YJL158C| CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YKL122C SRP21 protein-ER targeting ->
cell organization and biogenesis, protein metabolism, transport signal sequence binding ->
signal sequence binding nucleus, signal recognition particle ->
nucleus, cytoplasm REB1
YIL088C AVT7 transport ->
transport transporter activity ->
transporter activity vacuole ->
cytoplasm CBF1, SIP4
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane ACE2, SKN7
YNL192W CHS1 budding ->
asexual reproduction chitin synthase activity ->
acetylglucosaminyltransferase activity plasma membrane, chitosome ->
plasma membrane, cytoplasm STE12, SWI4, SWI5
YOR153W PDR5 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
ATP binding, transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane YAP6
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: cell organization and biogenesis (0.43) hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides (0.33) cytoplasm (0.67) SWI4 SKN7 (0.43)
Score: 0.29 0.13 0.73 0.333
P-value: 7.359E-01 (cell growth and/or maintenance) 8.615E-01 (hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides) 3.966E-03 (plasma membrane) 3.170E-02 (SKN7)

m_detoxificaton_orfnum2SD_n39(1) AND m_lipid_transporters_orfnum2SD_n8(1) => SimExpr(YOR153W) : 6

EXPR: (0.191) m_detoxificaton_orfnum2SD_n39 (P < 0.003) m_lipid_transporters_orfnum2SD_n8 (P < 0.003)

m_MERE4(1) AND m_MERE11(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YMR139W) OR SimExpr(other) : 5 1

EXPR: (0.186) m_anion_transporters_orfnum2SD_n15 (P < 0.000) m_MERE11 (P < 0.001) m_MERE4 (P < 0.000)

ORF SYMBOL P F C TF
YMR139W RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
transferase activity\, transferring phosphorus-containing groups MAL33, YJL206C
|YOR136W| IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on CH-OH group of donors mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YNL208W NO SYMBOL INO2
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups
YFR015C GSY1 glycogen metabolism ->
carbohydrate metabolism, energy pathways glycogen (starch) synthase activity ->
transferase activity\, transferring glycosyl groups INO4
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds cytosol ->
cytoplasm GCN4
Main: carbohydrate metabolism (0.60) transferase activity\, transferring phosphorus-containing groups (0.40) cytoplasm (1.00) MAL33 (0.20)
Score: 0.60 0.10 1.00 0.000
P-value: 3.509E-02 (glutamine family amino acid metabolism) 2.697E-01 (transferase activity) 4.731E+00 (cytoplasm) 1.985E-01 (MAL33)

m_intracellular_communication_orfnum2SD_n10(1) AND m_pentose-phosphate_pathway_orfnum2SD_n23(1) => SimExpr(YMR139W) OR SimExpr(other) : 5 1

m_intracellular_communication_orfnum2SD_n10(1) AND m_anion_transporters_orfnum2SD_n22(1) => SimExpr(YMR139W) OR SimExpr(other) : 5 2

EXPR: (0.225) m_intracellular_communication_orfnum2SD_n10 (P < 0.001) m_anion_transporters_orfnum2SD_n22 (P < 0.009)

ORF SYMBOL P F C TF
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
growth pattern, phosphorylation, small GTPase mediated signal transduction, protein modification protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
intracellular, cAMP-dependent protein kinase complex DOT6, SFL1
YNL241C ZWF1 pentose-phosphate shunt ->
monosaccharide catabolism, main pathways of carbohydrate metabolism, oxidoreduction coenzyme metabolism, hexose metabolism, water-soluble vitamin metabolism glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
intracellular ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YMR139W RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorylation, protein catabolism, sporulation (sensu Saccharomyces), protein modification glycogen synthase kinase 3 activity ->
protein serine/threonine kinase activity MAL33, YJL206C
|YKR075C| NO SYMBOL ABF1, IXR1, SFP1
|YML042W| CAT2 carnitine metabolism ->
biogenic amine metabolism, carboxylic acid metabolism, water-soluble vitamin metabolism carnitine O-acetyltransferase activity ->
acetyltransferase activity, O-acyltransferase activity peroxisomal matrix, mitochondrion, peroxisome ->
intracellular MAL13
YAL022C FUN26 nucleoside transport ->
nucleoside transport nucleoside transporter activity ->
nucleoside transporter activity intracellular, membrane ->
intracellular, membrane ADR1, FHL1, FZF1, IME4, MAC1, MATa1, NRG1, PDR1, SFP1, SMP1, STB1, SWI5, YFL044C
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
growth pattern, sporulation (sensu Saccharomyces), G-protein coupled receptor protein signaling pathway, small GTPase mediated signal transduction, second-messenger-mediated signaling RAS small monomeric GTPase activity ->
GTPase activity plasma membrane ->
membrane ACE2, SKN7
Main: phosphorylation (0.33) protein serine/threonine kinase activity (0.33) intracellular (0.80) SFP1 (0.43)
Score: 0.27 0.07 0.70 0.190
P-value: 1.443E-02 (RAS protein signal transduction) 1.875E-01 (protein serine/threonine kinase activity) 3.016E+00 (membrane) 2.686E-03 (SFP1)

m_other_energy_generation_activities_orfnum2SD_n9(1) AND m_g-proteins_orfnum2SD_n13(1) => SimExpr(YMR139W) OR SimExpr(other) : 5 2

EXPR: (0.222) m_g-proteins_orfnum2SD_n13 (P < 0.003) m_other_energy_generation_activities_orfnum2SD_n9 (P < 0.003)

m_other_energy_generation_activities_orfnum2SD_n9(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YMR139W) OR SimExpr(other) : 5 2

EXPR: (0.194) m_anion_transporters_orfnum2SD_n15 (P < 0.000) m_other_energy_generation_activities_orfnum2SD_n9 (P < 0.000)

ORF SYMBOL P F C TF
|YPL090C| RPS6A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, INO4, RAP1, YAP5
YMR139W RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MAL33, YJL206C
YNR074C NO SYMBOL GTS1
YIL070C MAM33 aerobic respiration ->
energy pathways mitochondrial matrix ->
cytoplasm HIR1, RPH1
|YIL040W| APQ12 RAP1, RLM1, SKN7, SMP1, STB1
YFL004W VTC2 protein localization, vacuole fusion (non-autophagic) ->
protein metabolism, cell organization and biogenesis vacuolar membrane ->
cytoplasm CIN5, GCN4, STE12, YAP1, YAP6
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity CRZ1
Main: protein metabolism (0.60) structural constituent of ribosome (0.33) cytoplasm (1.00) RAP1 (0.29)
Score: 0.40 0.00 1.00 0.048
P-value: 2.405E+00 (protein metabolism) 2.849E+00 (enzyme activity) 4.385E+00 (cytoplasm) 7.701E-01 (MAL33)

m_g-proteins_orfnum2SD_n13(1) AND REB1(1) => SimExpr(YMR139W) OR SimExpr(other) : 7 2

EXPR: (0.204) REB1 (P < 0.002) m_g-proteins_orfnum2SD_n13 (P < 0.001)

ORF SYMBOL P F C TF
YMR139W RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MAL33, YJL206C
YKR011C NO SYMBOL SWI4, SWI6
|YMR002W| NO SYMBOL NDD1, REB1, SWI6
YOL148C SPT20 chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein binding ->
protein binding SAGA complex ->
nucleus GRF10(Pho2), MATa1, MIG1, PHO4
|YNL233W| BNI4 cytokinesis ->
cell proliferation protein binding ->
protein binding contractile ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoplasm PHO4
YDR003W NO SYMBOL ARG80, FKH1, GCR2, GLN3
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YDR427W RPN9 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome regulatory particle (sensu Eukarya), proteasome regulatory particle\, lid subcomplex (sensu Eukarya) ->
cytoplasm, nucleus ARG81, IXR1
YDL007W RPT2 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism ATPase activity, endopeptidase activity ->
ATPase activity, endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus REB1
Main: protein metabolism (0.67) protein binding (0.33) cytoplasm (0.60) REB1 (0.33)
Score: 0.40 0.13 0.50 0.167
P-value: 4.244E-02 (proteolysis and peptidolysis) 5.413E-02 (endopeptidase activity) 1.095E-02 (proteasome regulatory particle (sensu Eukarya)) 7.688E-02 (REB1)

m_intracellular_communication_orfnum2SD_n10(1) AND m_cell_death_orfnum2SD_n22(1) AND m_MERE11(1) => SimExpr(YMR139W) : 5

EXPR: (0.175) m_MERE11 (P < 0.002) m_cell_death_orfnum2SD_n22 (P < 0.001) m_intracellular_communication_orfnum2SD_n10 (P < 0.000)

m_intracellular_communication_orfnum2SD_n10(1) AND m_cell_death_orfnum2SD_n22(1) AND ALPHA1'(1) => SimExpr(YMR139W) : 6

EXPR: (0.179) m_cell_death_orfnum2SD_n22 (P < 0.000) m_intracellular_communication_orfnum2SD_n10 (P < 0.000) ALPHA1' (P < 0.000)

m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8(1) AND m_nutritional_response_pathway_orfnum2SD_n12(1) => SimExpr(YDL079C) OR SimExpr(other) : 5 2

EXPR: (0.205) m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8 (P < 0.031) m_nutritional_response_pathway_orfnum2SD_n12 (P < 0.005)

ORF SYMBOL P F C TF
YHL024W RIM4 sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination ->
sporulation, nuclear division, DNA metabolism, cell cycle RNA binding ->
RNA binding intracellular ->
intracellular FKH2, PHD1
YHR210C NO SYMBOL GRF10(Pho2), PHO4
|YOL052C| SPE2 pantothenate biosynthesis ->
coenzymes and prosthetic group biosynthesis, coenzyme metabolism adenosylmethionine decarboxylase activity ->
adenosylmethionine decarboxylase activity
|YGR122W| NO SYMBOL CIN5
YDR073W SNF11 chromatin modeling ->
nuclear organization and biogenesis, DNA metabolism general RNA polymerase II transcription factor activity ->
general RNA polymerase II transcription factor activity intracellular ->
intracellular DAL81, RLM1
YAL022C FUN26 nucleoside transport ->
nucleobase\, nucleoside\, nucleotide and nucleic acid transport nucleoside transporter activity ->
nucleoside transporter activity intracellular, membrane ->
intracellular, membrane ADR1, FHL1, FZF1, IME4, MAC1, MATa1, NRG1, PDR1, SFP1, SMP1, STB1, SWI5, YFL044C
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphate metabolism, macromolecule catabolism, protein modification, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MTH1
Main: DNA metabolism (0.40) adenosylmethionine decarboxylase activity (0.20) intracellular (1.00) RLM1 (0.17)
Score: 0.10 0.00 1.00 0.000
P-value: 8.834E-01 (DNA metabolism) 2.849E+00 (enzyme activity) 3.997E+00 (intracellular) 7.474E-01 (ADR1)

m_regulation_of_amino-acid_metabolism_orfnum2SD_n10(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YDL079C) OR SimExpr(other) : 7 2

EXPR: (0.210) m_regulation_of_amino-acid_metabolism_orfnum2SD_n10 (P < 0.012) m_cell_death_orfnum2SD_n16 (P < 0.004)

ORF SYMBOL P F C TF
YOL012C HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
DNA binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
|YJR127C| ZMS1 transcription factor activity ->
DNA binding ABF1, FKH2, INO4, NDD1, PHD1, REB1
YLR460C NO SYMBOL CIN5, HAL9, YAP1
|YML042W| CAT2 carnitine metabolism ->
amine metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism carnitine O-acetyltransferase activity ->
transferase activity\, transferring acyl groups peroxisomal matrix, mitochondrion, peroxisome ->
cytoplasm MAL13
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds cytosol ->
cytoplasm GCN4
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
amine metabolism, alcohol metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism carnitine O-acetyltransferase activity ->
transferase activity\, transferring acyl groups mitochondrion ->
cytoplasm
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
hydrolase activity\, acting on ester bonds alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
transferase activity\, transferring phosphorus-containing groups MTH1
YGR050C NO SYMBOL DAL82, FKH2, HSF1, INO4, MAL13, NRG1, RAP1, SKN7, SWI4
Main: amino acid and derivative metabolism (0.50) DNA binding (0.29) cytoplasm (0.60) SWI4 FKH2 MAL13 INO4 (0.29)
Score: 0.33 0.10 0.30 0.143
P-value: 4.475E-04 (carnitine metabolism) 6.728E-04 (carnitine O-acetyltransferase activity) 2.021E+00 (mitochondrion) 7.992E-02 (MAL13)

m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8(1) AND m_peroxisomal_organization_orfnum2SD_n28(1) => SimExpr(YDL079C) : 5

EXPR: (0.174) m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8 (P < 0.006) m_peroxisomal_organization_orfnum2SD_n28 (P < 0.005)

ORF SYMBOL P F C TF
YIL056W NO SYMBOL CUP9, HAL9, MTH1, PHD1, ROX1, SWI4, YAP6
YDL047W SIT4 G1/S transition of mitotic cell cycle, protein kinase cascade, protein amino acid phosphorylation, cell wall organization and biogenesis, actin cytoskeleton organization and biogenesis ->
cell proliferation, signal transduction, phosphorus metabolism, cell organization and biogenesis, protein modification protein serine/threonine phosphatase activity ->
protein serine/threonine phosphatase activity HSF1, PHD1, SWI4
YPR065W ROX1 negative regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription DNA bending activity, specific transcriptional repressor activity ->
DNA bending activity, specific transcriptional repressor activity nuclear chromosome ->
chromosome, nucleus CIN5, HAP4, PHD1, SKN7, YAP1, YAP6
YDR073W SNF11 chromatin modeling ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism general RNA polymerase II transcription factor activity ->
general RNA polymerase II transcription factor activity nucleosome remodeling complex, SWI/SNF complex ->
nucleus DAL81, RLM1
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MTH1
Main: cell organization and biogenesis (0.50) general RNA polymerase II transcription factor activity (0.25) nucleus (1.00) PHD1 (0.60)
Score: 0.50 0.00 1.00 0.400
P-value: 8.194E-02 (protein amino acid phosphorylation) 2.445E-01 (transcription regulator activity) 2.880E+00 (nucleus) 3.806E-03 (PHD1)

m_cell_death_orfnum2SD_n22(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n17(1) => SimExpr(YAR035W) OR SimExpr(other) : 5 1

EXPR: (0.194) m_cell_death_orfnum2SD_n22 (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n17 (P < 0.002)

ORF SYMBOL P F C TF
|YGL049C| TIF4632 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex
YOL012C HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
YPL180W BIT89 glycerol metabolism ->
alcohol metabolism, glycerol ether metabolism, lipid metabolism REB1, RGT1, SIG1
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
amine metabolism, alcohol metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity mitochondrion ->
cytoplasm
YDR213W UPC2 steroid metabolism, sterol biosynthesis ->
lipid metabolism, alcohol metabolism, biosynthesis RNA polymerase II transcription factor activity ->
RNA polymerase II transcription factor activity cytoplasm, nucleus ->
cytoplasm, nucleus
YMR011W HXT2 hexose transport ->
transport glucose transporter activity, fructose transporter activity, mannose transporter activity ->
glucose transporter activity, fructose transporter activity, mannose transporter activity plasma membrane ->
plasma membrane PHD1
Main: alcohol metabolism (0.50) glucose transporter activity (0.20) cytoplasm (0.60) SWI4 (0.33)
Score: 0.27 0.00 0.40 0.000
P-value: 1.203E-02 (alcohol metabolism) 1.103E+00 (nucleic acid binding) 4.113E+00 (nucleus) 2.896E-01 (RGT1)

m_cell_death_orfnum2SD_n22(1) AND RAP1(1) => SimExpr(YGL147C) OR SimExpr(other) : 8 1

EXPR: (0.155) RAP1 (P < 0.026) m_cell_death_orfnum2SD_n22 (P < 0.000)

RAP1(1) AND m_MERE17(1) => SimExpr(YGL147C) OR SimExpr(other) : 5 1

EXPR: (0.148) RAP1 (P < 0.023) m_MERE17 (P < 0.000)

RAP1(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) => SimExpr(YGL147C) OR SimExpr(other) : 6 1

RAP1(1) AND m_g-proteins_orfnum2SD_n13(1) => SimExpr(YGL147C) OR SimExpr(other) : 5 1

EXPR: (0.182) RAP1 (P < 0.142) m_g-proteins_orfnum2SD_n13 (P < 0.000)

ORF SYMBOL P F C TF
YGL147C RPL9A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MBP1, RAP1, SWI4
YMR142C RPL13B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, YAP5
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
|YNL288W| CAF40 regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism CCR4-NOT complex ->
nucleus RAP1
YGR085C RPL11B protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MIG1
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
Main: biosynthesis (0.83) structural constituent of ribosome (0.60) cytoplasm (0.83) FHL1 RAP1 (0.67)
Score: 0.67 0.30 0.67 0.733
P-value: 1.770E-02 (biosynthesis) 1.653E-02 (structural constituent of ribosome) 2.579E-03 (cytosolic large ribosomal subunit (sensu Eukarya)) 1.370E-04 (FHL1)

RAP1(1) AND CSRE(1) => SimExpr(YGL147C) OR SimExpr(other) : 12 2

RAP1(1) AND MCM1'(1) => SimExpr(YGL147C) OR SimExpr(other) : 18 2

EXPR: (0.153) RAP1 (P < 0.000) MCM1' (P < 0.000)

RAP1(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YGL147C) : 5

EXPR: (0.107) RAP1 (P < 0.000) m_phosphate_transport_orfnum2SD_n18 (P < 0.000)

m_regulation_of_nucleotide_metabolism_orfnum2SD_n5(1) AND CSRE(1) => SimExpr(YOL019W) OR SimExpr(other) : 9 2

EXPR: (0.241) m_regulation_of_nucleotide_metabolism_orfnum2SD_n5 (P < 0.003) CSRE (P < 0.001)

m_RPE6(1) AND CSRE(1) => SimExpr(YLR406C) OR SimExpr(other) : 10 1

EXPR: (0.133) CSRE (P < 0.000) m_RPE6 (P < 0.027)

CSRE(1) AND m_RPE21(1) => SimExpr(YLR406C) OR SimExpr(other) : 10 3

ALPHA1(1) AND m_RPE21(1) => SimExpr(YLR406C) OR SimExpr(other) : 8 2

EXPR: (0.163) ALPHA1 (P < 0.000) m_RPE21 (P < 0.083)

SFF'(1) AND m_RPE21(1) => SimExpr(YLR406C) OR SimExpr(other) : 10 3

m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n20.scn(1) => SimExpr(YLR406C) OR SimExpr(other) : 5 2

EXPR: (0.212) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n20.scn (P < 0.013) m_biogenesis_of_chromosome_structure_orfnum2SD_n9 (P < 0.003)

m_ion_transporters_orfnum2SD_n6(1) AND m_nitrogen_and_sulphur_metabolism_orfnum2SD_n29(1) => SimExpr(YLR406C) OR SimExpr(other) : 5 2

EXPR: (0.190) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n29 (P < 0.005) m_ion_transporters_orfnum2SD_n6 (P < 0.029)

m_organization_of_cytoplasm_orfnum2SD_n27(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YLR406C) : 5

m_RPE6(1) AND m_RPE21(1) => SimExpr(YLR406C) : 5

m_phosphate_transport_orfnum2SD_n18(1) AND m_RPE21(1) => SimExpr(YLR406C) : 7

EXPR: (0.173) m_phosphate_transport_orfnum2SD_n18 (P < 0.001) m_RPE21 (P < 0.187)

m_RPE6(1) AND m_RPE34(1) => SimExpr(YLR406C) : 6

EXPR: (0.099) m_RPE34 (P < 0.003) m_RPE6 (P < 0.012)

m_RPE57(1) AND m_RPE34(1) => SimExpr(YLR406C) : 5

EXPR: (0.117) m_RPE57 (P < 0.013) m_RPE34 (P < 0.013)

m_cell_death_orfnum2SD_n22(1) AND m_RPE34(1) => SimExpr(YGL215W) OR SimExpr(other) : 7 3

EXPR: (0.247) m_cell_death_orfnum2SD_n22 (P < 0.001) m_RPE34 (P < 0.089)

m_homeostasis_of_metal_ions_orfnum2SD_n20(1) AND m_RPE34(1) => SimExpr(YGL215W) OR SimExpr(other) : 6 1

EXPR: (0.220) m_homeostasis_of_metal_ions_orfnum2SD_n20 (P < 0.005) m_RPE34 (P < 0.027)

m_LFTE17(1) AND m_ion_transporters_orfnum2SD_n7(1) => SimExpr(YGR043C) OR SimExpr(other) : 7 3

EXPR: (0.215) m_ion_transporters_orfnum2SD_n7 (P < 0.000) m_LFTE17 (P < 0.000)

ORF SYMBOL P F C TF
YGL179C NO SYMBOL SWI4, SWI6
YNL134C NO SYMBOL CAD1, HAL9, HSF1, NDD1, YAP1
|YGL006W| PMC1 calcium ion transport, calcium ion homeostasis ->
cation homeostasis, cation transport, metal ion homeostasis calcium-transporting ATPase activity ->
ATPase activity, calcium ion transporter activity, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole SKN7
YMR250W GAD1 response to oxidative stress, glutamate catabolism ->
response to oxidative stress, amine catabolism, amino acid metabolism glutamate decarboxylase activity ->
glutamate decarboxylase activity cytoplasm ->
cytoplasm
YGR043C NO SYMBOL SIG1
|YGR109C| CLB6 regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis ->
DNA replication and chromosome cycle, regulation of cell cycle, mitotic cell cycle, DNA metabolism cyclin-dependent protein kinase\, regulator activity ->
protein serine/threonine kinase activity, protein kinase regulator activity MBP1, STB1, SWI4, SWI6
YOR092W ECM3 cell wall organization and biogenesis ->
cell wall organization and biogenesis ATPase activity ->
ATPase activity STE12, YAP1
|YDR044W| HEM13 heme biosynthesis ->
heme metabolism, pigment biosynthesis, porphyrin biosynthesis coproporphyrinogen oxidase activity ->
coproporphyrinogen oxidase activity mitochondrial inner membrane ->
cytoplasm, inner membrane
YOR173W DCS2 CAD1
YGR008C STF2 response to dessication, ATP synthesis coupled proton transport ->
response to water deprivation, hydrogen transport, cation transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane INO2
Main: cation transport (0.33) ATPase activity (0.40) cytoplasm (1.00) YAP1 SWI4 SWI6 CAD1 (0.25)
Score: 0.07 0.10 1.00 0.107
P-value: 2.179E-01 (cation transport) 9.597E-01 (ATPase activity) 5.807E-01 (mitochondrial inner membrane) 6.151E-02 (CAD1)

m_cell_death_orfnum2SD_n22(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) AND m_MERE11(1) => SimExpr(YDR100W) OR SimExpr(other) : 5 1

EXPR: (0.189) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.000) m_MERE11 (P < 0.002) m_cell_death_orfnum2SD_n22 (P < 0.000)

m_peroxisomal_organization_orfnum2SD_n8(1) AND m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9(1) => SimExpr(YDR100W) : 5

EXPR: (0.167) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9 (P < 0.003) m_peroxisomal_organization_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YIL121W QDR2 PHO4, RAP1, SWI4
YNL241C ZWF1 pentose-phosphate shunt ->
pentose-phosphate shunt glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YDR100W TVP15 RAP1
YOR299W BUD7 bud site selection ->
bud site selection HSF1, MTH1
YJL057C NO SYMBOL SRD1
Main: pentose-phosphate shunt (0.50) glucose-6-phosphate 1-dehydrogenase activity (1.00) cytoplasm (1.00) PHO4 RAP1 (0.40)
Score: 0.00 0.00 0.00 0.200
P-value: 3.000E+00 (physiological processes) 0.000E+00 0.000E+00 1.023E-01 (PHO4)

m_other_energy_generation_activities_orfnum2SD_n16(1) AND m_other_cell_rescue_activities_orfnum2SD_n10(1) => SimExpr(YDL181W) OR SimExpr(other) : 5 1

EXPR: (0.195) m_other_cell_rescue_activities_orfnum2SD_n10 (P < 0.001) m_other_energy_generation_activities_orfnum2SD_n16 (P < 0.001)

ORF SYMBOL P F C TF
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane HAP4
|YDR111C| NO SYMBOL RAP1
YPR148C NO SYMBOL ABF1, MET4, NDD1, RAP1, YAP6
YGR086C PIL1 ASH1, SWI5
YJR009C TDH2 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity cytosol, lipid particle, cell wall, cytoplasm ->
cytoplasm, cell wall CBF1, GCR1, GCR2
YKL186C MTR2 poly(A)+ mRNA-nucleus export ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein binding ->
protein binding nuclear pore ->
nucleus, integral to membrane, endomembrane system SMP1, SWI5
Main: transport (0.67) protein binding (0.50) cytoplasm (0.67) SWI5 RAP1 (0.33)
Score: 0.33 0.00 0.67 0.133
P-value: 2.492E+00 (transport) 2.000E+00 2.654E-01 (integral to membrane) 8.964E-02 (SWI5)

m_other_energy_generation_activities_orfnum2SD_n16(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YDL181W) OR SimExpr(other) : 6 3

EXPR: (0.220) m_anion_transporters_orfnum2SD_n15 (P < 0.004) m_other_energy_generation_activities_orfnum2SD_n16 (P < 0.001)

ORF SYMBOL P F C TF
|YDL020C| RPN4 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus ABF1, CBF1, HSF1, PUT3, YAP1
YDR012W RPL4B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex ARG80, FZF1
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane HAP4
YOR312C RPL20B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, FKH2, GAT3, RAP1
|YDR134C| NO SYMBOL ASH1, NRG1, SOK2, SWI4
YGR086C PIL1 ASH1, SWI5
|YGR249W| MGA1 filamentous growth ->
cell organization and biogenesis ASH1, CIN5, CUP9, HSF1, IXR1, NRG1, PHD1, SKN7, SOK2, SWI4, YAP6
YOR187W TUF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity mitochondrial matrix, mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex HAP4, REB1
YNR001C CIT1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis citrate (SI)-synthase activity ->
citrate (SI)-synthase activity mitochondrial matrix, mitochondrion ->
cytoplasm RGM1
Main: biosynthesis (0.57) structural constituent of ribosome (0.40) cytoplasm (1.00) ASH1 (0.33)
Score: 0.43 0.10 1.00 0.139
P-value: 7.686E-01 (protein biosynthesis) 5.239E-01 (structural constituent of ribosome) 2.320E-01 (cytosolic large ribosomal subunit (sensu Eukarya)) 1.706E-03 (ASH1)

m_phosphate_transport_orfnum2SD_n18(1) AND HAP234(1) => SimExpr(YDL181W) OR SimExpr(other) : 6 1

EXPR: (0.187) m_phosphate_transport_orfnum2SD_n18 (P < 0.000) HAP234 (P < 0.035)

m_other_cell_rescue_activities_orfnum2SD_n10(1) AND m_anion_transporters_orfnum2SD_n9(1) => SimExpr(YGR252W) OR SimExpr(other) : 5 1

EXPR: (0.184) m_anion_transporters_orfnum2SD_n9 (P < 0.000) m_other_cell_rescue_activities_orfnum2SD_n10 (P < 0.000)

ORF SYMBOL P F C TF
YNL197C WHI3 regulation of cell size ->
cell organization and biogenesis RNA binding ->
RNA binding REB1
YGR252W GCN5 chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism histone acetyltransferase activity ->
histone acetyltransferase activity SAGA complex ->
nucleus ABF1
YPL141C NO SYMBOL FKH1, FKH2, NDD1
YJR127C ZMS1 transcription factor activity ->
transcription factor activity ABF1, FKH2, INO4, NDD1, PHD1, REB1
|YKL080W| VMA5 vacuolar acidification ->
cell homeostasis, cell organization and biogenesis, transport hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole
YIR023W DAL81 regulation of transcription from Pol II promoter, nitrogen utilization ->
nitrogen metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ABF1, YAP6
Main: cell organization and biogenesis (0.75) RNA binding (0.25) nucleus (0.67) ABF1 (0.60)
Score: 0.67 0.00 0.33 0.500
P-value: 1.807E+00 (cell organization and biogenesis) 4.333E-01 (transcription regulator activity) 3.428E+00 (nucleus) 4.453E-02 (ABF1)

m_purine_and_pyrimidine_transporters_orfnum2SD_n10(1) AND m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) => SimExpr(YKR042W) OR SimExpr(other) : 5 2

EXPR: (0.216) m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5 (P < 0.010) m_purine_and_pyrimidine_transporters_orfnum2SD_n10 (P < 0.004)

ORF SYMBOL P F C TF
YKR042W UTH1 mitochondrion organization and biogenesis ->
cell organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, intracellular, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
YKL189W HYM1 cytokinesis\, completion of separation, regulation of cell shape ->
cell proliferation, cell organization and biogenesis transcriptional repressor activity ->
transcriptional repressor activity intracellular ->
intracellular DIG1, STE12
|YGL040C| HEM2 heme biosynthesis ->
pigment metabolism, coenzymes and prosthetic group biosynthesis, coenzymes and prosthetic group metabolism, biosynthesis, heterocycle metabolism porphobilinogen synthase activity ->
porphobilinogen synthase activity
YPL218W SAR1 ER to Golgi transport ->
transport, vesicle-mediated transport SAR small monomeric GTPase activity ->
SAR small monomeric GTPase activity COPII vesicle coat ->
intracellular
|YOL007C| NO SYMBOL STB1
YNR054C NO SYMBOL HAP3, HAP5, IXR1, MCM1, RTG3, SFP1, SWI6
YPL078C ATP4 ATP synthesis coupled proton transport ->
transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
intracellular, integral to membrane, inner membrane REB1, ZAP1
Main: cell organization and biogenesis (0.40) SAR small monomeric GTPase activity (0.25) intracellular (1.00) STE12 MCM1 (0.40)
Score: 0.20 0.00 1.00 0.200
P-value: 7.690E-01 (development) 2.849E+00 (enzyme activity) 3.599E-01 (mitochondrial membrane) 2.288E-01 (STE12)

MCM1'(1) AND m_RPE34(1) => SimExpr(YKR042W) OR SimExpr(other) : 11 5

EXPR: (0.226) m_RPE34 (P < 0.220) MCM1' (P < 0.000)

m_anion_transporters_orfnum2SD_n32(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YKR042W) OR SimExpr(other) : 5 2

EXPR: (0.212) m_anion_transporters_orfnum2SD_n32 (P < 0.005) m_cell_death_orfnum2SD_n8 (P < 0.007)

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND m_RPE34(1) => SimExpr(YKR042W) OR SimExpr(other) : 5 2

EXPR: (0.209) m_metabolism_of_energy_reserves_orfnum2SD_n8 (P < 0.006) m_RPE34 (P < 0.167)

ORF SYMBOL P F C TF
YKR042W UTH1 mitochondrion organization and biogenesis ->
cytoplasm organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
YNL069C RPL16B protein biosynthesis ->
macromolecule biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YML073C RPL6A protein biosynthesis, ribosomal large subunit assembly and maintenance ->
macromolecule biosynthesis, cytoplasm organization and biogenesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, YAP5
|YGR088W| CTT1 response to stress ->
response to stress catalase activity ->
catalase activity cytoplasm ->
cytoplasm
YJL048C NO SYMBOL INO4, MAC1, MET4, SKN7
|YJL082W| IML2
YDR276C PMP3 cation transport ->
ion transport plasma membrane ->
plasma membrane GAT1
Main: cytoplasm organization and biogenesis (0.40) RNA binding (0.67) cytoplasm (0.80) FHL1 RAP1 SKN7 GAT3 YAP5 (0.40)
Score: 0.20 0.33 0.60 0.200
P-value: 2.300E+00 (protein biosynthesis) 4.640E-01 (structural constituent of ribosome) 1.287E-01 (cytosolic large ribosomal subunit (sensu Eukarya)) 1.036E-01 (YAP5)

m_RPE34(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YKR042W) OR SimExpr(other) : 8 2

EXPR: (0.195) m_cell_death_orfnum2SD_n8 (P < 0.000) m_RPE34 (P < 0.043)

m_LFTE17(1) AND m_RPE34(1) => SimExpr(YKR042W) OR SimExpr(other) : 6 2

EXPR: (0.213) m_LFTE17 (P < 0.000) m_RPE34 (P < 0.162)

m_RPE6(1) AND m_RPE34(1) => SimExpr(YKR042W) : 6

m_RPE57(1) AND m_RPE6(1) => SimExpr(YKR042W) : 7

m_RPE57(1) AND m_LFTE17(1) => SimExpr(YGR086C) OR SimExpr(other) : 6 2

m_other_energy_generation_activities_orfnum2SD_n16(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YGR086C) OR SimExpr(other) : 6 3

m_other_transport_facilitators_orfnum2SD_n10(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YGR086C) OR SimExpr(other) : 6 3

EXPR: (0.226) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.001) m_other_transport_facilitators_orfnum2SD_n10 (P < 0.038)

ORF SYMBOL P F C TF
|YJR150C| DAN1 sterol transport ->
transport cell wall (sensu Fungi) ->
cell wall PHO4
YOL019W NO SYMBOL SWI4
YAL039C CYC3 cytochrome c-heme linkage ->
protein metabolism holocytochrome c synthase activity ->
holocytochrome c synthase activity mitochondrial intermembrane space ->
cytoplasm
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
|YLR205C| HMX1 iron ion homeostasis ->
cell homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
YGR086C PIL1 ASH1, SWI5
YKL038W RGT1 glucose metabolism ->
alcohol metabolism, carbohydrate metabolism DNA binding, RNA polymerase II transcription factor activity, transcription co-repressor activity, transcriptional activator activity ->
DNA binding, RNA polymerase II transcription factor activity, transcription co-repressor activity, transcriptional activator activity nucleus ->
nucleus
YNL302C RPS19B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, RAP1
|YGL158W| RCK1 protein amino acid phosphorylation, regulation of meiosis ->
phosphorus metabolism, cell proliferation, protein metabolism protein serine/threonine kinase activity ->
protein serine/threonine kinase activity RLM1, SFL1, SOK2
Main: protein metabolism (0.43) DNA binding (0.17) cytoplasm (0.50) PHO4 (0.29)
Score: 0.24 0.00 0.20 0.048
P-value: 8.459E-01 (carbohydrate metabolism) 1.784E-01 (lyase activity) 1.878E+00 (cytosol) 2.638E-01 (PHO4)

m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) AND m_metabolism_of_energy_reserves_orfnum2SD_n8(1) => SimExpr(YGR086C) OR SimExpr(other) : 5 2

EXPR: (0.205) m_allantoin_and_allantoate_transporters_orfnum2SD_n6 (P < 0.001) m_metabolism_of_energy_reserves_orfnum2SD_n8 (P < 0.006)

ORF SYMBOL P F C TF
YNL208W NO SYMBOL INO2
YJL048C NO SYMBOL INO4, MAC1, MET4, SKN7
YGR086C PIL1 ASH1, SWI5
YPR160W GPH1 glycogen catabolism ->
glycogen catabolism glycogen phosphorylase activity ->
glycogen phosphorylase activity cytoplasm ->
cytoplasm MAC1, MTH1, NDD1
YIL045W PIG2 protein phosphatase regulator activity ->
protein phosphatase regulator activity CIN5
|YKR084C| HBS1 protein biosynthesis ->
protein biosynthesis PHO4
|YPR014C| NO SYMBOL CIN5, MAL13, PHD1
Main: glycogen catabolism (0.50) protein phosphatase regulator activity (0.50) cytoplasm (1.00) MAC1 CIN5 (0.29)
Score: 0.00 0.00 0.00 0.095
P-value: 3.979E+00 (metabolism) 2.000E+00 0.000E+00 8.983E-02 (MAC1)

STRE'(1) AND m_rRSE10(1) => SimExpr(YGR086C) : 6

EXPR: (0.190) m_rRSE10 (P < 0.001) STRE' (P < 0.015)

ORF SYMBOL P F C TF
YKR095W MLP1 protein-nucleus import ->
protein metabolism, transport nuclear membrane, nucleoplasm ->
nucleus, endomembrane system FHL1, RAP1
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
cell organization and biogenesis, phosphorus metabolism, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YGR086C PIL1 ASH1, SWI5
YLR168C NO SYMBOL HAP4
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
Main: cell organization and biogenesis (0.50) RAS small monomeric GTPase activity (0.33) cytoplasm (0.50) ASH1 (0.17)
Score: 0.33 0.00 0.17 0.000
P-value: 6.545E-03 (RAS protein signal transduction) 2.077E+00 (enzyme activity) 2.499E+00 (membrane) 5.792E-01 (ASH1)

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND ECB(1) => SimExpr(YGR086C) : 7

EXPR: (0.179) ECB (P < 0.000) m_metabolism_of_energy_reserves_orfnum2SD_n8 (P < 0.000)

m_cell_death_orfnum2SD_n22(1) AND m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9(1) => SimExpr(YOL087C) OR SimExpr(other) : 7 3

EXPR: (0.226) m_cell_death_orfnum2SD_n22 (P < 0.000) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9 (P < 0.025)

m_tricarboxylic-acid_pathway_orfnum2SD_n9(1) AND m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9(1) => SimExpr(YOL087C) OR SimExpr(other) : 5 2

EXPR: (0.236) m_tricarboxylic-acid_pathway_orfnum2SD_n9 (P < 0.009) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9 (P < 0.077)

ORF SYMBOL P F C TF
|YHR210C| NO SYMBOL GRF10(Pho2), PHO4
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YOL087C NO SYMBOL DAL82
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
nucleotidyltransferase activity
YDR069C DOA4 regulation of DNA replication, protein deubiquitination ->
catabolism, protein metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ubiquitin-specific protease activity, endopeptidase activity ->
cysteine-type peptidase activity, endopeptidase activity proteasome complex (sensu Eukarya) ->
cytoplasm, nucleus UGA3
|YPR015C| NO SYMBOL
YIL124W AYR1 phosphatidic acid biosynthesis ->
biosynthesis, membrane lipid metabolism, organic acid metabolism, lipid metabolism acylglycerone-phosphate reductase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor endoplasmic reticulum, lipid particle, cytoplasm ->
cytoplasm
Main: alcohol metabolism (0.50) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.50) cytoplasm (1.00) PHO4 (0.50)
Score: 0.67 0.17 1.00 0.167
P-value: 1.203E-01 (glucose metabolism) 6.354E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 5.219E-01 (endoplasmic reticulum) 1.835E-01 (PHO4)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9(1) => SimExpr(YOL087C) OR SimExpr(other) : 5 1

EXPR: (0.193) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9 (P < 0.004) m_other_signal-transduction_activities_orfnum2SD_n8 (P < 0.000)

m_allantoin_and_allantoate_transporters_orfnum2SD_n7(1) AND ALPHA1(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n9(1) => SimExpr(YOL087C) : 5

EXPR: (0.158) m_tricarboxylic-acid_pathway_orfnum2SD_n9 (P < 0.000) ALPHA1 (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n7 (P < 0.000)

ORF SYMBOL P F C TF
YOL087C NO SYMBOL DAL82
YML057W CMP2 cell ion homeostasis, adaptation to pheromone during conjugation with cellular fusion ->
cell ion homeostasis, adaptation to pheromone during conjugation with cellular fusion calcium-dependent protein serine/threonine phosphatase activity ->
calcium-dependent protein serine/threonine phosphatase activity cytoplasm ->
intracellular MSN4
YNL090W RHO2 microtubule-based process, cell wall organization and biogenesis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
microtubule-based process, cell wall organization and biogenesis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity intracellular ->
intracellular INO4, REB1
YNR001C CIT1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis ->
tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis citrate (SI)-synthase activity ->
citrate (SI)-synthase activity mitochondrial matrix, mitochondrion ->
intracellular RGM1
YKL187C NO SYMBOL
Main: glutamate biosynthesis (0.33) signal transducer activity (0.33) intracellular (1.00) DAL82 (0.25)
Score: 0.00 0.00 1.00 0.000
P-value: 4.224E+00 (cell growth and/or maintenance) 9.891E-01 (hydrolase activity) 4.460E+00 (cytoplasm) 2.425E-01 (RGM1)

m_homeostasis_of_metal_ions_orfnum2SD_n20(1) AND m_RPE34(1) => SimExpr(YDR276C) OR SimExpr(other) : 5 2

ALPHA1(1) AND MCB(1) => SimExpr(YNL233W) OR SimExpr(other) : 22 10

MCB(1) AND m_nutritional_response_pathway_orfnum2SD_n7(1) => SimExpr(YNL233W) OR SimExpr(other) : 6 2

MCB(1) AND STE12(1) => SimExpr(YNL233W) OR SimExpr(other) : 5 1

EXPR: (0.180) STE12 (P < 0.000) MCB (P < 0.064)

ORF SYMBOL P F C TF
YPR135W CTF4 DNA dependent DNA replication, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation DNA binding ->
DNA binding nucleus ->
nucleus BAS1, DIG1, FZF1
|YMR279C| NO SYMBOL IXR1, MIG1, MTH1, RFX1, SWI4, SWI6
YGR189C CRH1 cell wall, incipient bud site ->
cell wall, incipient bud site GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YNL233W BNI4 cytokinesis ->
cell proliferation protein binding ->
protein binding contractile ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoplasm PHO4
YDR309C GIC2 axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) ->
asexual reproduction, signal transduction, cell organization and biogenesis small GTPase regulatory/interacting protein activity ->
small GTPase regulatory/interacting protein activity actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site ->
cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6
YJR043C POL32 leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, mismatch repair, postreplication repair ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, mitotic cell cycle delta DNA polymerase activity ->
delta DNA polymerase activity delta DNA polymerase complex, nucleus ->
cytoplasm, nucleus MOT3, RTS2
Main: cell proliferation (0.75) DNA binding (0.25) cytoplasm (0.60) SWI4 (0.50)
Score: 0.50 0.00 0.50 0.200
P-value: 9.954E-02 (DNA dependent DNA replication) 1.806E+00 (binding) 4.845E-03 (incipient bud site) 3.084E-02 (SWI4)

m_peroxisomal_organization_orfnum2SD_n28(1) AND m_phosphate_transport_orfnum2SD_n5(1) => SimExpr(YMR086W) OR SimExpr(other) : 5 2

EXPR: (0.249) m_phosphate_transport_orfnum2SD_n5 (P < 0.040) m_peroxisomal_organization_orfnum2SD_n28 (P < 0.043)

ORF SYMBOL P F C TF
YOR348C PUT4 neutral amino acid transport ->
neutral amino acid transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid permease activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YKL160W ELF1 cell growth ->
cell growth
YKR102W FLO10 CIN5, CUP9, NRG1, PHD1, RLM1, ROX1, SFP1, SMP1, YAP6
|YGL067W| NPY1 NADH metabolism ->
NADH metabolism NAD+ pyrophosphatase activity ->
NAD+ pyrophosphatase activity cytoplasm, peroxisome ->
cytoplasm, peroxisome STE12
|YAL037W| NO SYMBOL AZF1, CIN5
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MTH1
YMR086W NO SYMBOL FKH1
Main: response to stress (0.25) amino acid permease activity (0.33) peroxisome (0.50) CIN5 (0.33)
Score: 0.00 0.00 0.00 0.067
P-value: 5.723E+00 (cell growth and/or maintenance) 2.849E+00 (enzyme activity) 3.000E+00 (cell) 7.150E-01 (CIN5)

m_other_energy_generation_activities_orfnum2SD_n20(1) AND m_anion_transporters_orfnum2SD_n17(1) => SimExpr(YMR086W) : 5

EXPR: (0.190) m_other_energy_generation_activities_orfnum2SD_n20 (P < 0.005) m_anion_transporters_orfnum2SD_n17 (P < 0.000)

ORF SYMBOL P F C TF
YDR049W NO SYMBOL
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy derivation by oxidation of organic compounds, electron transport, phosphate metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YDR050C TPI1 gluconeogenesis, glycolysis ->
alcohol biosynthesis, alcohol catabolism, carbohydrate metabolism, monosaccharide metabolism, carbohydrate biosynthesis, carbohydrate catabolism, energy derivation by oxidation of organic compounds triose-phosphate isomerase activity ->
triose-phosphate isomerase activity cytosol, cytoplasm ->
cytoplasm GCR1, GCR2, HSF1, INO4, SIG1
YIL045W PIG2 protein phosphatase regulator activity ->
protein phosphatase regulator activity CIN5
YMR086W NO SYMBOL FKH1
Main: energy derivation by oxidation of organic compounds (1.00) ubiquinol-cytochrome c reductase activity (0.33) cytoplasm (1.00) GCR2 (0.25)
Score: 1.00 0.00 1.00 0.000
P-value: 1.287E-01 (energy pathways) 2.509E+00 (enzyme activity) 4.460E+00 (cytoplasm) 4.921E-01 (SIG1)

m_g-proteins_orfnum2SD_n12(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) AND m_anion_transporters_orfnum2SD_n23(1) => SimExpr(YNR047W) OR SimExpr(other) : 5 2

EXPR: (0.202) m_allantoin_and_allantoate_transporters_orfnum2SD_n13 (P < 0.000) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_anion_transporters_orfnum2SD_n23 (P < 0.001)

ORF SYMBOL P F C TF
YMR291W NO SYMBOL RAP1
|YIL052C| RPL34B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex RME1
|YKR072C| SIS2 G1/S transition of mitotic cell cycle, salinity response, regulation of mitotic cell cycle, coenzyme A biosynthesis ->
response to abiotic stimulus, biosynthesis, coenzymes and prosthetic group metabolism, cell proliferation protein phosphatase inhibitor activity, phosphopantothenoylcysteine decarboxylase activity ->
phosphatase inhibitor activity, carboxy-lyase activity nucleus, cytoplasm ->
nucleus, cytoplasm
YNR047W NO SYMBOL MIG1
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
oxo-acid-lyase activity, carboxy-lyase activity CRZ1
YNL045W NO SYMBOL MSN1
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
phosphotransferase activity\, alcohol group as acceptor MTH1
Main: biosynthesis (0.75) carboxy-lyase activity (0.50) cytoplasm (1.00) MTH1 (0.17)
Score: 0.67 0.17 1.00 0.000
P-value: 3.633E-01 (response to stress) 7.911E-03 (carboxy-lyase activity) 4.869E+00 (cytoplasm) 1.784E-01 (MSN1)

m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n12(1) AND m_MERE11(1) => SimExpr(YOR052C) OR SimExpr(other) : 7 2

EXPR: (0.229) m_MERE11 (P < 0.024) m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n12 (P < 0.019)

ORF SYMBOL P F C TF
|YOL051W| GAL11 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase II transcription mediator activity ->
RNA polymerase II transcription mediator activity mediator complex ->
intracellular
|YGR288W| MAL13 regulation of transcription\, DNA-dependent, carbohydrate metabolism ->
carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity ->
transcription factor activity nucleus ->
intracellular
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrial matrix ->
intracellular IME4, MTH1, RTG1, YJL206C
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrial matrix, mitochondrion ->
intracellular MET4
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
intracellular, endomembrane system MAL13, REB1
YOR052C NO SYMBOL
YPR124W CTR1 protein biosynthesis, copper ion import ->
biosynthesis, transport, protein metabolism copper uptake transporter activity ->
di-\, tri-valent inorganic cation transporter activity, transition metal ion transporter activity plasma membrane ->
plasma membrane CIN5, INO2, INO4, MAC1, SMP1
YGR019W UGA1 nitrogen utilization ->
nitrogen metabolism 4-aminobutyrate aminotransferase activity ->
transaminase activity intracellular ->
intracellular IXR1
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
phosphoric ester hydrolase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
Main: carbohydrate metabolism (0.50) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.25) intracellular (0.75) SMP1 (0.20)
Score: 0.32 0.04 0.54 0.000
P-value: 1.641E-02 (tricarboxylic acid cycle) 1.410E-01 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 4.145E-01 (mitochondrial matrix) 1.000E+00

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) => SimExpr(YPR145W) OR SimExpr(other) : 6 2

EXPR: (0.234) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.018) m_other_nucleotide-metabolism_activities_orfnum2SD_n17 (P < 0.018)

ORF SYMBOL P F C TF
YNL160W YGP1 response to stress, response to nutrients ->
response to stress, response to extracellular stimulus, response to abiotic stimulus cell wall (sensu Fungi) ->
cell wall
|YJL109C| UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
snoRNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YKL210W UBA1 ubiquitin cycle ->
catabolism, protein metabolism ubiquitin activating enzyme activity ->
ubiquitin activating enzyme activity nucleus, cytoplasm ->
nucleus, cytoplasm SKO1
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YDR284C DPP1 phospholipid metabolism ->
lipid metabolism diacylglycerol pyrophosphate phosphatase activity, phosphatidate phosphatase activity ->
diacylglycerol pyrophosphate phosphatase activity, phosphatidate phosphatase activity vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole ABF1, FKH1, GCR2, GLN3, GTS1, RIM101, RTG1, SWI6
YKL128C PMU1 INO4
|YFR009W| GCN20 regulation of translational elongation ->
biosynthesis, protein metabolism cytosol, cytosolic ribosome (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
YPL271W ATP15 ATP synthesis coupled proton transport ->
transport hydrogen-transporting ATP synthase activity ->
hydrogen-transporting ATP synthase activity proton-transporting ATP synthase\, central stalk (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane HAP4
Main: biosynthesis (0.29) ubiquitin activating enzyme activity (0.20) cytoplasm (0.67) GLN3 (0.40)
Score: 0.10 0.00 0.53 0.100
P-value: 4.321E+00 (biosynthesis) 2.641E+00 (enzyme activity) 1.649E+00 (ribonucleoprotein complex) 7.322E-02 (GLN3)

m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) AND m_anion_transporters_orfnum2SD_n10(1) => SimExpr(YPR145W) OR SimExpr(other) : 6 2

EXPR: (0.221) m_anion_transporters_orfnum2SD_n10 (P < 0.003) m_other_nucleotide-metabolism_activities_orfnum2SD_n17 (P < 0.005)

ORF SYMBOL P F C TF
|YIL033C| BCY1 response to stress, pseudohyphal growth, signal transduction, response to heat ->
response to stress, cell organization and biogenesis, signal transduction, response to abiotic stimulus cAMP-dependent protein kinase inhibitor activity ->
cAMP-dependent protein kinase inhibitor activity nucleus, cytoplasm ->
nucleus, cytoplasm
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YOR015W NO SYMBOL
YPL131W RPL5 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1
YMR298W NO SYMBOL CIN5
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
|YPL075W| GCR1 positive regulation of transcription from Pol II promoter, positive regulation of glycolysis ->
catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription, regulation of metabolism DNA binding, transcriptional activator activity ->
DNA binding, transcriptional activator activity nucleus ->
nucleus RTS2
YGR257C NO SYMBOL
Main: biosynthesis (0.60) DNA binding (0.20) cytoplasm (0.50) RAP1 (0.40)
Score: 0.40 0.00 0.33 0.100
P-value: 1.892E+00 (biosynthesis) 1.647E+00 (nucleic acid binding) 5.009E+00 (nucleus) 1.000E+00

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn(1) => SimExpr(YPR145W) OR SimExpr(other) : 5 2

m_glyoxylate_cycle_orfnum2SD_n7(1) AND m_ion_transporters_orfnum2SD_n14(1) => SimExpr(YPR145W) OR SimExpr(other) : 5 1

EXPR: (0.171) m_ion_transporters_orfnum2SD_n14 (P < 0.008) m_glyoxylate_cycle_orfnum2SD_n7 (P < 0.001)

ORF SYMBOL P F C TF
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
ligase activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
intracellular INO2, INO4
YJL171C NO SYMBOL CIN5, MTH1
YML088W UFO1 response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism ubiquitin-protein ligase activity ->
ligase activity HAP4, RAP1, SKN7
|YKL034W| TUL1 protein transport ->
transport ligase activity ->
ligase activity intracellular ->
intracellular
YIL133C RPL16A protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
intracellular FHL1, GAT3, PDR1, PUT3, RAP1, RGM1, SFP1, SMP1, YAP5
Main: biosynthesis (0.60) ligase activity (0.60) intracellular (1.00) RAP1 (0.60)
Score: 0.50 0.30 1.00 0.300
P-value: 9.414E-01 (biosynthesis) 3.477E-03 (ligase activity) 5.433E-01 (ribosome) 7.610E-02 (RAP1)

m_phosphate_transport_orfnum2SD_n18(1) AND HAP234(1) => SimExpr(YPR145W) OR SimExpr(other) : 5 2

m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6(1) AND m_amino-acid_biosynthesis_orfnum2SD_n9(1) => SimExpr(YPR145W) OR SimExpr(other) : 5 1

EXPR: (0.220) m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6 (P < 0.013) m_amino-acid_biosynthesis_orfnum2SD_n9 (P < 0.032)

ORF SYMBOL P F C TF
|YOL165C| AAD15 aldehyde metabolism ->
aldehyde metabolism benzyl alcohol dehydrogenase activity ->
benzyl alcohol dehydrogenase activity FKH1, GAT3
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YKL063C NO SYMBOL FKH1, HAL9, MAC1, PHD1
YKR011C NO SYMBOL SWI4, SWI6
YMR233W NO SYMBOL
YJR025C BNA1 nicotinamide adenine dinucleotide biosynthesis ->
coenzymes and prosthetic group metabolism, biosynthesis, water-soluble vitamin metabolism, vitamin metabolism 3-hydroxyanthranilate 3\,4-dioxygenase activity ->
3-hydroxyanthranilate 3\,4-dioxygenase activity cytoplasm ->
cytoplasm GCN4, SUM1, SWI6
Main: biosynthesis (0.67) benzyl alcohol dehydrogenase activity (0.33) cytoplasm (1.00) FKH1 SUM1 SWI6 GCN4 (0.40)
Score: 0.33 0.00 0.00 0.300
P-value: 1.907E+00 (biosynthesis) 2.882E-01 (oxidoreductase activity) 0.000E+00 4.860E-02 (GCN4)

CSRE(1) AND HAP234(1) => SimExpr(YPR145W) : 6

SFF'(1) AND m_amino-acid_transport_orfnum2SD_n14(1) AND m_anion_transporters_orfnum2SD_n22(1) => SimExpr(YKL085W) OR SimExpr(other) : 5 1

EXPR: (0.193) SFF' (P < 0.000) m_amino-acid_transport_orfnum2SD_n14 (P < 0.002) m_anion_transporters_orfnum2SD_n22 (P < 0.000)

ORF SYMBOL P F C TF
|YFL017C| GNA1 UDP-N-acetylglucosamine biosynthesis ->
amine metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, carbohydrate metabolism glucosamine-phosphate N-acetyltransferase activity ->
glucosamine-phosphate N-acetyltransferase activity STP2
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
cell organization and biogenesis, phosphorus metabolism, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YJL213W NO SYMBOL
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YDR381W YRA1 mRNA-nucleus export ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding transcription export complex ->
nucleus ARO80
Main: cell organization and biogenesis (0.40) RNA binding (0.20) cytoplasm (0.75) SFL1 (0.20)
Score: 0.40 0.00 0.50 0.000
P-value: 4.711E-01 (carbohydrate metabolism) 9.703E-01 (transferase activity) 3.918E+00 (cytoplasm) 5.792E-01 (IME4)

m_other_cation_transporters_orfnum2SD_n3(1) AND m_anion_transporters_orfnum2SD_n22(1) => SimExpr(YKL085W) OR SimExpr(other) : 5 2

EXPR: (0.250) m_other_cation_transporters_orfnum2SD_n3 (P < 0.035) m_anion_transporters_orfnum2SD_n22 (P < 0.034)

ORF SYMBOL P F C TF
|YNL139C| RLR1 mRNA-nucleus export, DNA recombination, RNA elongation from Pol II promoter ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, RNA localization nucleic acid binding ->
nucleic acid binding THO complex ->
nucleus ABF1
YGR060W ERG25 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
cell organization and biogenesis, phosphorus metabolism, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YIL169C NO SYMBOL FKH2
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
|YGR050C| NO SYMBOL DAL82, FKH2, HSF1, INO4, MAL13, NRG1, RAP1, SKN7, SWI4
YOR317W FAA1 N-terminal protein myristoylation, lipid metabolism, lipid transport ->
biosynthesis, lipid metabolism, transport, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
long-chain-fatty-acid-CoA-ligase activity lipid particle ->
cytoplasm ASH1, CIN5, HSF1, INO4, RAP1
Main: biosynthesis (0.40) long-chain-fatty-acid-CoA-ligase activity (0.20) cytoplasm (0.80) HSF1 (0.43)
Score: 0.30 0.00 0.60 0.190
P-value: 3.990E-01 (lipid metabolism) 3.837E-01 (oxidoreductase activity) 3.294E+00 (cytoplasm) 9.558E-03 (HSF1)

m_nitrogen_and_sulphur_metabolism_orfnum2SD_n22(1) AND STRE'(1) => SimExpr(YKL085W) OR SimExpr(other) : 5 2

EXPR: (0.226) STRE' (P < 0.024) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n22 (P < 0.025)

ORF SYMBOL P F C TF
|YNL241C| ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
nucleotidyltransferase activity
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in linear amidines cytosol ->
cytoplasm GCN4
YOR062C NO SYMBOL GRF10(Pho2)
|YGR050C| NO SYMBOL DAL82, FKH2, HSF1, INO4, MAL13, NRG1, RAP1, SKN7, SWI4
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
guanyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane ACE2, SKN7
Main: carbohydrate metabolism (0.60) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.40) cytoplasm (0.75) SKN7 (0.50)
Score: 0.50 0.10 0.50 0.267
P-value: 7.310E-02 (carbohydrate metabolism) 7.413E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 4.385E+00 (cytoplasm) 3.804E-02 (SKN7)

m_organization_of_cytoplasm_orfnum2SD_n27(1) => SimExpr(YKL085W) OR SimExpr(other) : 7 2

EXPR: (0.228) m_organization_of_cytoplasm_orfnum2SD_n27 (P < 0.696)

m_amino-acid_transport_orfnum2SD_n20(1) AND m_other_cation_transporters_orfnum2SD_n3(1) => SimExpr(YKL085W) OR SimExpr(other) : 5 2

EXPR: (0.212) m_other_cation_transporters_orfnum2SD_n3 (P < 0.001) m_amino-acid_transport_orfnum2SD_n20 (P < 0.004)

m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n12(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YKL085W) OR SimExpr(other) : 7 3

EXPR: (0.233) m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n12 (P < 0.007) m_amino-acid_transport_orfnum2SD_n20 (P < 0.015)

m_cell_death_orfnum2SD_n22(1) AND m_organization_of_cytoplasm_orfnum2SD_n27(1) => SimExpr(YKL085W) : 5

EXPR: (0.179) m_organization_of_cytoplasm_orfnum2SD_n27 (P < 0.246) m_cell_death_orfnum2SD_n22 (P < 0.000)

m_organization_of_cytoplasm_orfnum2SD_n27(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YKL085W) : 5

MCM1'(1) AND HAP234(1) => SimExpr(YMR143W) OR SimExpr(other) : 9 4

EXPR: (0.226) HAP234 (P < 0.121) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
|YPL177C| CUP9 copper ion homeostasis, transcription initiation from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell homeostasis, transcription specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus BAS1, CIN5, MAC1, PHD1, SWI4, YAP6
YNL069C RPL16B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YMR143W RPS16A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, YAP5
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane HAP4
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
carbon-oxygen lyase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YPR035W GLN1 nitrogen metabolism, glutamine biosynthesis ->
nitrogen metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis glutamate-ammonia ligase activity ->
ligase activity\, forming carbon-nitrogen bonds cytoplasm ->
cytoplasm CIN5, DAL81, FKH1, FKH2, GLN3, HSF1, INO4, MSN1, REB1, SWI4
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
oxidoreductase activity\, acting on diphenols and related substances as donors, primary active transporter activity, cation transporter activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
|YKL198C| PTK1 polyamine transport ->
transport protein kinase activity ->
transferase activity\, transferring phosphorus-containing groups INO2
|YJL079C| PRY1 nuclear membrane, endoplasmic reticulum ->
nucleus, cytoplasm, endomembrane system NDD1, PHD1, RAP1
|YNL040W| NO SYMBOL FZF1, GCR2, RTG3, YAP7
YDR377W ATP17 ATP synthesis coupled proton transport ->
transport hydrogen-transporting ATP synthase activity ->
cation transporter activity proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane ARO80, HAP2, HAP3, HAP4, RPH1
YDL140C RPO21 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase II\, core complex ->
nucleus REB1
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides Golgi vesicle, cytosol ->
cytoplasm, Golgi apparatus MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: biosynthesis (0.36) structural constituent of ribosome (0.20) cytoplasm (0.82) REB1 HAP4 RAP1 CIN5 (0.23)
Score: 0.25 0.07 0.71 0.167
P-value: 4.375E-02 (ATP synthesis coupled proton transport) 1.008E-01 (hydrogen ion transporter activity) 3.537E-02 (proton-transporting ATP synthase complex) 2.498E-02 (HAP4)

m_anion_transporters_orfnum2SD_n17(1) AND HAP234(1) => SimExpr(YMR143W) OR SimExpr(other) : 5 1

EXPR: (0.189) HAP234 (P < 0.029) m_anion_transporters_orfnum2SD_n17 (P < 0.001)

ORF SYMBOL P F C TF
YNL052W COX5A aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors\, oxygen as acceptor, primary active transporter activity, hydrogen ion transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
YMR143W RPS16A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, YAP5
YPR035W GLN1 nitrogen metabolism, glutamine biosynthesis ->
nitrogen metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis glutamate-ammonia ligase activity ->
ammonia ligase activity cytoplasm ->
cytoplasm CIN5, DAL81, FKH1, FKH2, GLN3, HSF1, INO4, MSN1, REB1, SWI4
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
oxidoreductase activity\, acting on diphenols and related substances as donors\, cytochrome as acceptor, primary active transporter activity, hydrogen ion transporter activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YKL141W SDH3 oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways succinate dehydrogenase activity ->
succinate dehydrogenase activity respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
|YPR185W| APG13 protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
Main: energy pathways (0.50) primary active transporter activity (0.33) cytoplasm (0.83) HAP4 (0.40)
Score: 0.33 0.07 0.67 0.100
P-value: 1.115E-03 (oxidative phosphorylation) 1.711E-02 (hydrogen ion transporter activity) 4.542E-05 (mitochondrial electron transport chain) 5.366E-02 (HAP4)

m_glycolysis_and_gluconeogenesis_orfnum2SD_n4(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) => SimExpr(YMR143W) OR SimExpr(other) : 5 1

EXPR: (0.140) m_glycolysis_and_gluconeogenesis_orfnum2SD_n4 (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n6 (P < 0.000)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND HAP234(1) => SimExpr(YMR143W) OR SimExpr(other) : 11 5

EXPR: (0.232) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) HAP234 (P < 0.147)

ORF SYMBOL P F C TF
|YNL207W| RIO2 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleocytoplasmic transporter activity, protein kinase activity ->
nucleocytoplasmic transporter activity, transferase activity\, transferring phosphorus-containing groups cytosol, nucleus ->
cytoplasm, nucleus ABF1, MAL33
|YDR344C| NO SYMBOL MSS11
YHL010C NO SYMBOL
YMR143W RPS16A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural molecule activity cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, YAP5
|YDL240W| LRG1 small GTPase mediated signal transduction, cell wall biosynthesis (sensu Fungi) ->
signal transduction, cell organization and biogenesis, biosynthesis Rho GTPase activator activity ->
small GTPase regulatory/interacting protein activity FKH1
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on CH-OH group of donors mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YFR049W YMR31 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural molecule activity mitochondrial small ribosomal subunit ->
cytoplasm, ribonucleoprotein complex MAL33
YPR035W GLN1 nitrogen metabolism, glutamine biosynthesis ->
nitrogen metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis glutamate-ammonia ligase activity ->
ligase activity\, forming carbon-nitrogen bonds cytoplasm ->
cytoplasm CIN5, DAL81, FKH1, FKH2, GLN3, HSF1, INO4, MSN1, REB1, SWI4
|YNL040W| NO SYMBOL FZF1, GCR2, RTG3, YAP7
|YGR008C| STF2 response to dessication, ATP synthesis coupled proton transport ->
response to abiotic stimulus, transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane INO2
YKL141W SDH3 oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways succinate dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-CH group of donors respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
YPL078C ATP4 ATP synthesis coupled proton transport ->
transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane REB1, ZAP1
YDR377W ATP17 ATP synthesis coupled proton transport ->
transport hydrogen-transporting ATP synthase activity ->
cation transporter activity proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane ARO80, HAP2, HAP3, HAP4, RPH1
YLR395C COX8 aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors, primary active transporter activity, cation transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
YDL140C RPO21 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase II\, core complex ->
nucleus REB1
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides Golgi vesicle, cytosol ->
cytoplasm, Golgi apparatus MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: biosynthesis (0.38) structural molecule activity (0.25) cytoplasm (0.92) REB1 (0.29)
Score: 0.27 0.08 0.85 0.110
P-value: 1.102E-03 (ATP synthesis coupled proton transport) 1.522E-01 (hydrogen ion transporter activity) 1.134E-03 (proton-transporting ATP synthase complex) 8.697E-02 (REB1)

MCM1'(1) AND m_cell_death_orfnum2SD_n16(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn(1) => SimExpr(YDR381W) OR SimExpr(other) : 5 1

EXPR: (0.202) m_cell_death_orfnum2SD_n16 (P < 0.004) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn (P < 0.000) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YAL060W BDH1 butanediol fermentation ->
energy derivation by oxidation of organic compounds (R\,R)-butanediol dehydrogenase activity ->
(R\,R)-butanediol dehydrogenase activity cytoplasm ->
cytoplasm
|YOR382W| FIT2 siderochrome transport ->
siderochrome transport cell wall (sensu Fungi) ->
cell wall (sensu Fungi)
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to DNA damage, cytoplasm organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YLR414C NO SYMBOL
YDR381W YRA1 mRNA-nucleus export ->
intracellular transport, RNA localization RNA binding ->
RNA binding transcription export complex ->
transcription export complex ARO80
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol biosynthesis, regulation of biosynthesis, monosaccharide metabolism, carbohydrate metabolism, negative regulation of metabolism, carbohydrate biosynthesis, energy derivation by oxidation of organic compounds, regulation of metabolism ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: energy derivation by oxidation of organic compounds (0.40) RNA binding (0.33) cytoplasm (0.33) NDD1 (0.67)
Score: 0.10 0.00 0.00 0.333
P-value: 2.804E-01 (energy pathways) 2.000E+00 3.999E+00 (intracellular) 1.638E-01 (NDD1)

SFF(1) AND m_phosphate_transport_orfnum2SD_n8(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YDR381W) OR SimExpr(other) : 11 4

EXPR: (0.231) SFF (P < 0.000) m_phosphate_transport_orfnum2SD_n8 (P < 0.000) m_amino-acid_transport_orfnum2SD_n14 (P < 0.006)

ORF SYMBOL P F C TF
|YDR440W| DOT1 histone methylation, chromatin silencing at telomere, regulation of meiosis ->
cell organization and biogenesis, cell cycle, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription protein-lysine N-methyltransferase activity ->
protein-lysine N-methyltransferase activity nucleus ->
nucleus CRZ1, DOT6, PHO4, RTG1
YOL019W NO SYMBOL SWI4
|YOR381W| FRE3 iron-siderochrome transport, iron ion homeostasis ->
transport, cell homeostasis ferric-chelate reductase activity ->
ferric-chelate reductase activity plasma membrane, integral to membrane ->
membrane CIN5, PDR1, YAP6
YOL103W ITR2 myo-inositol transport ->
transport myo-inositol transporter activity ->
myo-inositol transporter activity membrane ->
membrane DIG1, MTH1
YOL086C ADH1 fermentation ->
energy pathways alcohol dehydrogenase activity ->
alcohol dehydrogenase activity cytosol ->
cytoplasm GCR1, GCR2, GTS1, RAP1
YKL126W YPK1 protein amino acid phosphorylation, sphingolipid metabolism, endocytosis ->
phosphorus metabolism, lipid metabolism, transport, protein metabolism protein serine/threonine kinase activity ->
protein serine/threonine kinase activity plasma membrane, cytosol, bud neck ->
membrane, cytoplasm, site of polarized growth (sensu Fungi)
YIL075C RPN2 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism receptor activity, endopeptidase activity ->
receptor activity, endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus MSS11, REB1, SFL1
YJR148W BAT2 branched chain family amino acid biosynthesis, amino acid catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis, catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity cytoplasm ->
cytoplasm NDD1, SKN7, SWI4
YJL158C CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
|YOR011W| AUS1 sterol transport ->
transport ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity membrane ->
membrane
YGR180C RNR4 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity nucleus, cytoplasm ->
nucleus, cytoplasm CIN5, MBP1, RAP1, RFX1, SWI6
YDR381W YRA1 mRNA-nucleus export ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding transcription export complex ->
nucleus ARO80
|YOR385W| NO SYMBOL
YGR055W MUP1 sulfur amino acid transport ->
transport L-methionine porter activity ->
L-methionine porter activity integral to plasma membrane ->
membrane DAL81, INO4, MET4, STP1
YNR001C CIT1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis citrate (SI)-synthase activity ->
citrate (SI)-synthase activity mitochondrial matrix, mitochondrion ->
cytoplasm RGM1
Main: transport (0.46) structural constituent of cell wall (0.08) cytoplasm (0.54) SWI4 (0.25)
Score: 0.32 0.00 0.51 0.106
P-value: 1.629E+00 (amino acid biosynthesis) 9.261E-01 (oxidoreductase activity) 1.939E-01 (plasma membrane) 7.454E-01 (SWI4)

m_RPE57(1) AND m_LFTE17(1) => SimExpr(YDR381W) OR SimExpr(other) : 6 2

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn(1) => SimExpr(YDR381W) OR SimExpr(other) : 5 2

EXPR: (0.210) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.000) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn (P < 0.000)

ORF SYMBOL P F C TF
YML092C PRE8 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid permease activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
|YNL250W| RAD50 double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication, telomerase-independent telomere maintenance ->
cell organization and biogenesis, cell proliferation, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, response to biotic stimulus ATPase activity, protein binding, double-stranded DNA binding ->
ATPase activity, protein binding, double-stranded DNA binding nucleus ->
nucleus ABF1, MAC1
|YLR178C| TFS1 regulation of proteolysis and peptidolysis ->
catabolism, protein metabolism, regulation of metabolism lipid binding, enzyme inhibitor activity ->
lipid binding, enzyme inhibitor activity soluble fraction ->
soluble fraction
YKL141W SDH3 oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways succinate dehydrogenase activity ->
succinate dehydrogenase activity respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
YDR381W YRA1 mRNA-nucleus export ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding transcription export complex ->
nucleus ARO80
Main: catabolism (0.43) enzyme inhibitor activity (0.29) nucleus (0.50) ABF1 (0.25)
Score: 0.29 0.05 0.27 0.000
P-value: 4.125E-02 (response to DNA damage) 6.939E-03 (enzyme inhibitor activity) 3.310E+00 (nucleus) 6.475E-01 (ARO80)

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_pentose-phosphate_pathway_orfnum2SD_n19(1) => SimExpr(YDR381W) : 5

EXPR: (0.164) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.001) m_pentose-phosphate_pathway_orfnum2SD_n19 (P < 0.001)

m_RPE17(1) AND m_other_cation_transporters_orfnum2SD_n14(1) => SimExpr(YJR123W) OR SimExpr(other) : 5 2

m_anion_transporters_orfnum2SD_n32(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YJR123W) OR SimExpr(other) : 9 4

EXPR: (0.208) m_anion_transporters_orfnum2SD_n32 (P < 0.002) m_phosphate_transport_orfnum2SD_n18 (P < 0.001)

ORF SYMBOL P F C TF
YKR042W UTH1 mitochondrion organization and biogenesis ->
cell organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
YOL109W NO SYMBOL CIN5, RAP1, SKN7
YOR032C HMS1 pseudohyphal growth ->
cell organization and biogenesis transcription factor activity ->
transcription factor activity CUP9, HAL9, INO4, NRG1, RAP1, SFP1, YAP6
YLR367W RPS22B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex AZF1, CHA4, CUP9, FHL1, FZF1, GCR1, HAL9, MBP1, NDD1, REB1, RME1, ROX1, YAP1, YAP6
YJR123W RPS5 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GRF10(Pho2), HSF1, MSN4, YAP1
|YNL285W| NO SYMBOL MCM1, MOT3
YLR354C TAL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transaldolase activity ->
transaldolase activity cytoplasm ->
cytoplasm MBP1
|YGR035C| NO SYMBOL CIN5, MET4, SMP1, YAP6
|YIR016W| NO SYMBOL DAL82, RAP1
|YGR142W| BTN2 regulation of pH, intracellular protein transport ->
cell homeostasis, transport cytosol ->
cytoplasm HSF1, MSN4
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MTH1
YNL015W PBI2 regulation of proteolysis and peptidolysis, vacuole fusion (non-autophagic) ->
cell organization and biogenesis, catabolism, protein metabolism, regulation of metabolism endopeptidase inhibitor activity ->
endopeptidase inhibitor activity cytoplasm, vacuole (sensu Fungi) ->
cytoplasm INO4
YKL060C FBA1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism fructose-bisphosphate aldolase activity ->
fructose-bisphosphate aldolase activity cytosol, cytoplasm ->
cytoplasm ABF1, GCR2, GRF10(Pho2), INO4, MET4, RAP1
Main: protein metabolism (0.44) structural constituent of ribosome (0.29) cytoplasm (1.00) RAP1 (0.31)
Score: 0.44 0.05 1.00 0.282
P-value: 2.457E-01 (hexose catabolism) 1.161E+00 (structural constituent of ribosome) 3.207E-01 (cytosolic small ribosomal subunit (sensu Eukarya)) 1.239E-01 (HSF1)

m_PNDE6(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n4(1) => SimExpr(YJR123W) OR SimExpr(other) : 5 1

EXPR: (0.224) m_deoxyribonucleotide_metabolism_orfnum2SD_n4 (P < 0.054) m_PNDE6 (P < 0.001)

ORF SYMBOL P F C TF
YKR042W UTH1 mitochondrion organization and biogenesis ->
cytoplasm organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
|YLR394W| CST9 DNA replication and chromosome cycle ->
cell cycle DNA binding ->
DNA binding SMP1
YJR123W RPS5 protein biosynthesis ->
macromolecule biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GRF10(Pho2), HSF1, MSN4, YAP1
YHR027C RPN1 ubiquitin-dependent protein catabolism ->
macromolecule catabolism, protein metabolism endopeptidase activity, receptor activity ->
endopeptidase activity, receptor activity proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YDL128W VCX1 calcium ion transport, calcium ion homeostasis ->
cell ion homeostasis, ion transport, cation homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cytoplasm, vacuole MAC1, STE12
YPL221W BOP1 CBF1
Main: protein metabolism (0.40) DNA binding (0.25) cytoplasm (1.00) HSF1 STE12 (0.40)
Score: 0.10 0.00 1.00 0.200
P-value: 3.699E+00 (protein metabolism) 2.000E+00 (molecular_function) 9.744E-01 (cytosol) 1.411E-01 (HSF1)

RAP1(1) AND m_RPE17(1) => SimExpr(YJR123W) : 5

RAP1(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YJR123W) : 5

m_nutritional_response_pathway_orfnum2SD_n7(1) AND m_anion_transporters_orfnum2SD_n4(1) => SimExpr(YOL086C) OR SimExpr(other) : 9 4

EXPR: (0.212) m_nutritional_response_pathway_orfnum2SD_n7 (P < 0.000) m_anion_transporters_orfnum2SD_n4 (P < 0.003)

ORF SYMBOL P F C TF
YPR149W NCE102 protein secretion ->
protein secretion integral to membrane, endoplasmic reticulum, cytoplasm ->
integral to membrane, cytoplasm CIN5, FKH2, GRF10(Pho2), HSF1, NDD1, PUT3, RAP1, SKN7, SWI4, YAP6
|YGL034C| NO SYMBOL
YOR343C NO SYMBOL DIG1, RAP1, STE12
YDR511W ACN9 carbon utilization by utilization of organic compounds, gluconeogenesis ->
carbon utilization by utilization of organic compounds, alcohol biosynthesis, monosaccharide metabolism, carbohydrate metabolism, carbohydrate biosynthesis, energy derivation by oxidation of organic compounds mitochondrial intermembrane space ->
cytoplasm MBP1, STB1
YOL086C ADH1 fermentation ->
energy derivation by oxidation of organic compounds alcohol dehydrogenase activity ->
alcohol dehydrogenase activity cytosol ->
cytoplasm GCR1, GCR2, GTS1, RAP1
|YLR377C| FBP1 gluconeogenesis ->
alcohol biosynthesis, monosaccharide metabolism, carbohydrate metabolism, carbohydrate biosynthesis, energy derivation by oxidation of organic compounds fructose-bisphosphatase activity ->
carbohydrate phosphatase activity cytosol ->
cytoplasm
YKR091W SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm DIG1, RLM1, STE12
YGL215W CLG1 cell cycle ->
cell cycle cyclin-dependent protein kinase\, regulator activity ->
protein serine/threonine kinase activity, protein kinase regulator activity cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex
YKL152C GPM1 gluconeogenesis, glycolysis ->
alcohol biosynthesis, alcohol catabolism, carbohydrate metabolism, monosaccharide metabolism, carbohydrate biosynthesis, carbohydrate catabolism, energy derivation by oxidation of organic compounds phosphoglycerate mutase activity ->
phosphoglycerate mutase activity cytosol ->
cytoplasm GCR1, GCR2, HSF1, RAP1
YAL061W NO SYMBOL
|YGR035C| NO SYMBOL CIN5, MET4, SMP1, YAP6
|YDL079C| MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphate metabolism, macromolecule catabolism, protein modification, protein metabolism glycogen synthase kinase 3 activity ->
protein serine/threonine kinase activity MTH1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cellular morphogenesis, sporulation (sensu Fungi), cell surface receptor linked signal transduction, intracellular signaling cascade RAS small monomeric GTPase activity ->
GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
Main: energy derivation by oxidation of organic compounds (0.44) protein serine/threonine kinase activity (0.33) cytoplasm (0.75) RAP1 (0.44)
Score: 0.17 0.07 0.54 0.250
P-value: 5.058E-03 (gluconeogenesis) 6.810E-01 (protein serine/threonine kinase activity) 1.205E+00 (cytosol) 1.322E-01 (RAP1)

m_deoxyribonucleotide_metabolism_orfnum2SD_n10(1) AND m_amino-acid_transport_orfnum2SD_n3(1) AND SCB(1) => SimExpr(YHL021C) OR SimExpr(other) : 5 2

EXPR: (0.205) SCB (P < 0.000) m_deoxyribonucleotide_metabolism_orfnum2SD_n10 (P < 0.000) m_amino-acid_transport_orfnum2SD_n3 (P < 0.001)

ORF SYMBOL P F C TF
|YKR042W| UTH1 mitochondrion organization and biogenesis ->
cytoplasm organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
YAL002W VPS8 late endosome to vacuole transport ->
cytoplasm organization and biogenesis, intracellular transport, vesicle-mediated transport membrane fraction ->
membrane fraction MBP1, PHD1
YHL021C NO SYMBOL GAT1, MAL13, MAL33, MTH1
YPL195W APL5 Golgi to vacuole transport ->
cytoplasm organization and biogenesis, secretory pathway, intracellular transport, vesicle-mediated transport AP-3 adaptor complex ->
cytoplasm SWI5
YMR002W NO SYMBOL NDD1, REB1, SWI6
|YNL232W| CSL4 35S primary transcript processing, mRNA catabolism ->
cytoplasm organization and biogenesis, macromolecule catabolism, transcription, RNA metabolism 3'-5' exoribonuclease activity ->
3'-5' exoribonuclease activity nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus HAP3, RCS1
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
Main: cytoplasm organization and biogenesis (0.80) 3'-5' exoribonuclease activity (0.50) cytoplasm (0.80) NDD1 (0.29)
Score: 0.60 0.00 0.60 0.048
P-value: 2.892E-01 (cytoplasm organization and biogenesis) 2.849E+00 (enzyme activity) 1.397E+00 (mitochondrion) 3.536E-01 (NDD1)

m_allantoin_and_allantoate_transporters_orfnum2SD_n7(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YGL009C) OR SimExpr(other) : 5 2

EXPR: (0.201) m_anion_transporters_orfnum2SD_n20 (P < 0.002) m_allantoin_and_allantoate_transporters_orfnum2SD_n7 (P < 0.000)

ORF SYMBOL P F C TF
YGR175C ERG1 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism squalene monooxygenase activity ->
squalene monooxygenase activity endoplasmic reticulum, lipid particle ->
cytoplasm YAP5
YDR134C NO SYMBOL ASH1, NRG1, SOK2, SWI4
YOL122C SMF1 manganese ion transport ->
transport manganese ion transporter activity ->
manganese ion transporter activity plasma membrane, vacuole (sensu Fungi) ->
plasma membrane, cytoplasm
YHR208W BAT1 branched chain family amino acid biosynthesis, amino acid catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis, catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity mitochondrial matrix ->
cytoplasm LEU3, PHO4
|YPL047W| NO SYMBOL STB1
|YKR072C| SIS2 G1/S transition of mitotic cell cycle, salinity response, regulation of mitotic cell cycle, coenzyme A biosynthesis ->
response to abiotic stimulus, biosynthesis, coenzymes and prosthetic group metabolism, cell proliferation protein phosphatase inhibitor activity, phosphopantothenoylcysteine decarboxylase activity ->
protein phosphatase inhibitor activity, phosphopantothenoylcysteine decarboxylase activity nucleus, cytoplasm ->
nucleus, cytoplasm
YGL009C LEU1 leucine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis 3-isopropylmalate dehydratase activity ->
3-isopropylmalate dehydratase activity cytosol ->
cytoplasm LEU3
Main: biosynthesis (0.80) manganese ion transporter activity (0.20) cytoplasm (1.00) LEU3 (0.40)
Score: 0.60 0.00 1.00 0.100
P-value: 7.697E-03 (branched chain family amino acid biosynthesis) 8.699E-02 (lyase activity) 1.822E+00 (cytoplasm) 1.949E-02 (LEU3)

m_RPE17(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YGL009C) OR SimExpr(other) : 7 1

EXPR: (0.211) m_amino-acid_transport_orfnum2SD_n20 (P < 0.001) m_RPE17 (P < 0.010)

LYS14(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YGL009C) OR SimExpr(other) : 7 3

EXPR: (0.243) LYS14 (P < 0.003) m_amino-acid_transport_orfnum2SD_n20 (P < 0.014)

m_RPE17(1) AND LYS14(1) => SimExpr(YGL009C) OR SimExpr(other) : 5 2

EXPR: (0.239) LYS14 (P < 0.010) m_RPE17 (P < 0.048)

ORF SYMBOL P F C TF
YPL218W SAR1 ER to Golgi transport ->
transport, vesicle-mediated transport SAR small monomeric GTPase activity ->
GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides COPII vesicle coat ->
cytoplasm
|YKL105C| NO SYMBOL
YNL302C RPS19B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, RAP1
YDL185W TFP1 intron homing, vacuolar acidification, protein metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell homeostasis, protein metabolism, cell organization and biogenesis, transport hydrogen-exporting ATPase activity, endodeoxyribonuclease activity ->
ATP binding, deoxyribonuclease activity, hydrogen ion transporter activity, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides, endonuclease activity vacuolar membrane (sensu Fungi), hydrogen-transporting ATPase V1 domain ->
cytoplasm, vacuole SWI4
YKL180W RPL17A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1
YGL009C LEU1 leucine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis 3-isopropylmalate dehydratase activity ->
3-isopropylmalate dehydratase activity cytosol ->
cytoplasm LEU3
|YMR253C| NO SYMBOL MCM1
Main: biosynthesis (0.60) structural constituent of ribosome (0.40) cytoplasm (1.00) FHL1 RAP1 (0.40)
Score: 0.60 0.20 1.00 0.100
P-value: 1.959E+00 (intracellular transport) 7.291E-01 (structural constituent of ribosome) 3.122E-01 (cytosol) 1.047E-01 (FHL1)

m_other_pheromone_response_activities_orfnum2SD_n12(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YGL009C) OR SimExpr(other) : 9 4

EXPR: (0.250) m_amino-acid_transport_orfnum2SD_n20 (P < 0.019) m_other_pheromone_response_activities_orfnum2SD_n12 (P < 0.001)

ORF SYMBOL P F C TF
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid transporter activity, polyamine transporter activity, porter activity plasma membrane ->
plasma membrane SWI5
|YNL092W| NO SYMBOL MSS11
YML073C RPL6A protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, YAP5
|YDR462W| MRPL28 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex ABF1
YDL240W LRG1 small GTPase mediated signal transduction, cell wall biosynthesis (sensu Fungi) ->
signal transduction, cell organization and biogenesis, biosynthesis Rho GTPase activator activity ->
GTPase activator activity FKH1
|YML042W| CAT2 carnitine metabolism ->
amine metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism carnitine O-acetyltransferase activity ->
transferase activity\, transferring groups other than amino-acyl groups peroxisomal matrix, mitochondrion, peroxisome ->
cytoplasm MAL13
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
amine metabolism, alcohol metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism carnitine O-acetyltransferase activity ->
transferase activity\, transferring groups other than amino-acyl groups mitochondrion ->
cytoplasm
YDR276C PMP3 cation transport ->
transport plasma membrane ->
plasma membrane GAT1
YGR126W NO SYMBOL CHA4, GTS1, SWI6
|YIL099W| SGA1 sporulation (sensu Saccharomyces) ->
sporulation glucan 1\,4-alpha-glucosidase activity ->
hydrolase activity\, hydrolyzing O-glycosyl compounds vacuole (sensu Fungi) ->
cytoplasm ASH1, CIN5, CUP9, MOT3, NRG1, PHD1, ROX1, SKN7, SOK2, YAP6
YGL009C LEU1 leucine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis 3-isopropylmalate dehydratase activity ->
hydro-lyase activity cytosol ->
cytoplasm LEU3
YOR130C ORT1 arginine biosynthesis, nuclear migration (sensu Saccharomyces) ->
amine metabolism, cell organization and biogenesis, cell proliferation, cell cycle, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ornithine transporter activity ->
amino acid transporter activity mitochondrial membrane ->
cytoplasm GCN4
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: biosynthesis (0.55) transferase activity\, transferring groups other than amino-acyl groups (0.22) cytoplasm (0.78) ASH1 PHD1 CUP9 SKN7 NRG1 YAP6 ROX1 (0.17)
Score: 0.40 0.08 0.61 0.015
P-value: 1.681E-03 (carnitine metabolism) 1.731E-03 (carnitine O-acetyltransferase activity) 9.112E-01 (large ribosomal subunit) 1.979E-01 (ASH1)

m_cell_death_orfnum2SD_n22(1) AND m_g-proteins_orfnum2SD_n12(1) AND m_anion_transporters_orfnum2SD_n4(1) => SimExpr(YMR011W) OR SimExpr(other) : 7 3

EXPR: (0.232) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_cell_death_orfnum2SD_n22 (P < 0.000) m_anion_transporters_orfnum2SD_n4 (P < 0.000)

ORF SYMBOL P F C TF
YPR010C RPA135 transcription from Pol I promoter ->
transcription\, DNA-dependent DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
|YFL036W| RPO41 mitochondrial genome maintenance, transcription from mitochondrial promoter ->
organelle organization and biogenesis, transcription\, DNA-dependent DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups mitochondrial matrix ->
cytoplasm
YOL086C ADH1 fermentation ->
fermentation alcohol dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors cytosol ->
cytoplasm GCR1, GCR2, GTS1, RAP1
|YMR182C| RGM1 negative regulation of transcription from Pol II promoter ->
regulation of transcription, transcription from Pol II promoter, transcription\, DNA-dependent RNA polymerase II transcription factor activity ->
RNA polymerase II transcription factor activity nucleus ->
nucleus REB1
YGR086C PIL1 ASH1, SWI5
YGL215W CLG1 cell cycle ->
cell cycle cyclin-dependent protein kinase\, regulator activity ->
transferase activity\, transferring phosphorus-containing groups, protein kinase regulator activity cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
biogenic amine metabolism, alcohol metabolism, carboxylic acid metabolism, water-soluble vitamin metabolism carnitine O-acetyltransferase activity ->
transferase activity\, transferring acyl groups mitochondrion ->
cytoplasm
YMR011W HXT2 hexose transport ->
monosaccharide transport glucose transporter activity, fructose transporter activity, mannose transporter activity ->
monosaccharide transporter activity, hexose transporter activity plasma membrane ->
plasma membrane PHD1
YPR115W NO SYMBOL IME4, INO4, UGA3
|YDL079C| MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorylation, protein catabolism, protein modification glycogen synthase kinase 3 activity ->
transferase activity\, transferring phosphorus-containing groups MTH1
Main: transcription\, DNA-dependent (0.38) transferase activity\, transferring phosphorus-containing groups (0.50) cytoplasm (0.43) GCR2 (0.14)
Score: 0.11 0.21 0.19 0.000
P-value: 9.063E-01 (transcription\, DNA-dependent) 2.023E-02 (DNA-directed RNA polymerase activity) 2.713E+00 (mitochondrion) 1.000E+00

GCN4(1) AND m_ionic_homeostasis_orfnum2SD_n6(1) => SimExpr(YNL019C) OR SimExpr(other) : 5 1

EXPR: (0.199) m_ionic_homeostasis_orfnum2SD_n6 (P < 0.000) GCN4 (P < 0.006)

ORF SYMBOL P F C TF
YNL019C NO SYMBOL
YPL264C NO SYMBOL
YFR030W MET10 sulfate assimilation ->
sulfur utilization sulfite reductase (NADPH) activity ->
sulfite reductase (NADPH) activity CBF1, DAL82, MET31, MET4, SIG1
|YFR021W| AUT10 sporulation (sensu Saccharomyces), autophagy, protein-vacuolar targeting, vacuolar protein processing/maturation ->
sporulation (sensu Fungi), autophagy, cytoplasm organization and biogenesis, intracellular transport, protein metabolism, protein transport cytosol ->
cytosol GTS1, PHO4
YNL033W NO SYMBOL GAT1, MAL13
YMR319C FET4 low affinity iron ion transport, intracellular copper ion transport ->
intracellular transport, ion transport iron ion transporter activity ->
iron ion transporter activity integral to plasma membrane ->
integral to plasma membrane AZF1, CIN5, INO4, MAC1, NRG1, PHD1, RCS1, ROX1, SFL1, SOK2, YAP6
Main: intracellular transport (0.67) sulfite reductase (NADPH) activity (0.50) integral to plasma membrane (0.50) DAL82 (0.25)
Score: 0.33 0.00 0.00 0.000
P-value: 1.000E+00 (intracellular transport) 4.458E-01 (transporter activity) 3.000E+00 (cell) 8.617E-01 (GAT1)

m_phosphate_metabolism_orfnum2SD_n18(1) AND m_nitrogen_and_sulphur_utilization_orfnum2SD_n4(1) => SimExpr(YJL172W) : 5

EXPR: (0.154) m_nitrogen_and_sulphur_utilization_orfnum2SD_n4 (P < 0.000) m_phosphate_metabolism_orfnum2SD_n18 (P < 0.002)

ORF SYMBOL P F C TF
YJL143W TIM17 mitochondrial translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity mitochondrial inner membrane pre-sequence translocase complex ->
cytoplasm, inner membrane
YGR065C VHT1 biotin transport ->
transport biotin transporter activity ->
biotin transporter activity plasma membrane ->
plasma membrane
YJL172W CPS1 nitrogen metabolism, proteolysis and peptidolysis ->
nitrogen metabolism, catabolism, protein metabolism gly-X carboxypeptidase activity ->
gly-X carboxypeptidase activity vacuole (sensu Fungi) ->
cytoplasm PHO4
YOR153W PDR5 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane YAP6
YOR317W FAA1 N-terminal protein myristoylation, lipid metabolism, lipid transport ->
biosynthesis, lipid metabolism, transport, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
long-chain-fatty-acid-CoA-ligase activity lipid particle ->
cytoplasm ASH1, CIN5, HSF1, INO4, RAP1
Main: transport (0.80) protein transporter activity (0.20) cytoplasm (0.60) ASH1 (0.33)
Score: 0.80 0.00 0.40 0.000
P-value: 5.789E-02 (transport) 6.556E-02 (transporter activity) 2.555E-01 (plasma membrane) 3.395E-01 (ASH1)

m_nutritional_response_pathway_orfnum2SD_n8(1) AND m_amino-acid_biosynthesis_orfnum2SD_n9(1) => SimExpr(YHR212C) OR SimExpr(other) : 5 1

EXPR: (0.219) m_amino-acid_biosynthesis_orfnum2SD_n9 (P < 0.005) m_nutritional_response_pathway_orfnum2SD_n8 (P < 0.001)

ORF SYMBOL P F C TF
YKL063C NO SYMBOL FKH1, HAL9, MAC1, PHD1
YDR359C VID21 ABF1
YOR316C COT1 cobalt ion transport, zinc ion transport, zinc ion homeostasis ->
cobalt ion transport, zinc ion transport, zinc ion homeostasis di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity ->
di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity vacuole (sensu Fungi) ->
vacuole (sensu Fungi) FKH2, INO2, INO4, NDD1, RAP1
|YFL030W| AGX1 glyoxylate cycle ->
glyoxylate cycle alanine-glyoxylate aminotransferase activity ->
alanine-glyoxylate aminotransferase activity
YAR060C NO SYMBOL
YHR212C NO SYMBOL
Main: glyoxylate cycle (0.50) cobalt ion transporter activity (0.50) vacuole (sensu Fungi) (1.00) ABF1 (0.33)
Score: 0.00 0.00 0.00 0.000
P-value: 3.000E+00 (physiological processes) 2.000E+00 0.000E+00 6.770E-01 (HAL9)

ALPHA2'(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YDR462W) OR SimExpr(other) : 5 1

EXPR: (0.191) m_cell_death_orfnum2SD_n8 (P < 0.000) ALPHA2' (P < 0.001)

m_amino-acid_transport_orfnum2SD_n14(1) AND m_other_cation_transporters_orfnum2SD_n18(1) => SimExpr(YDR462W) OR SimExpr(other) : 5 2

EXPR: (0.205) m_amino-acid_transport_orfnum2SD_n14 (P < 0.004) m_other_cation_transporters_orfnum2SD_n18 (P < 0.000)

ORF SYMBOL P F C TF
YDR462W MRPL28 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex ABF1
|YJL213W| NO SYMBOL
YGR121C MEP1 ammonium transport ->
transport ammonium transporter activity ->
ammonium transporter activity plasma membrane ->
plasma membrane CIN5
YIL075C RPN2 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism receptor activity, endopeptidase activity ->
receptor activity, endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus MSS11, REB1, SFL1
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
|YJR076C| CDC11 cellular morphogenesis, cytokinesis, cell wall organization and biogenesis, axial budding, conjugation with cellular fusion, establishment of cell polarity (sensu Saccharomyces) ->
cell proliferation, budding, conjugation, cell organization and biogenesis, sexual reproduction structural constituent of cytoskeleton, phosphatidylinositol binding ->
structural constituent of cytoskeleton, phosphatidylinositol binding septin ring (sensu Saccharomyces), spore wall (sensu Fungi), prospore membrane, shmoo tip ->
cell wall, prospore, site of polarized growth (sensu Fungi), cell cortex, cytoskeleton
YMR086W NO SYMBOL FKH1
Main: protein metabolism (0.40) ammonium transporter activity (0.20) cytoplasm (0.60) ABF1 (0.20)
Score: 0.20 0.00 0.30 0.000
P-value: 9.187E-01 (catabolism) 8.244E-01 (structural molecule activity) 1.267E+00 (cytosol) 6.086E-01 (SFL1)

ALPHA1(1) AND m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND m_nitrogen_and_sulphur_utilization_orfnum2SD_n4(1) => SimExpr(YGL191W) OR SimExpr(other) : 7 3

EXPR: (0.234) m_nitrogen_and_sulphur_utilization_orfnum2SD_n4 (P < 0.004) ALPHA1 (P < 0.001) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.000)

ORF SYMBOL P F C TF
YMR008C PLB1 glycerophospholipid metabolism ->
lipid metabolism lysophospholipase activity ->
lysophospholipase activity cell wall (sensu Fungi) ->
cell wall RAP1
YNR067C DSE4 cytokinesis\, completion of separation ->
cell proliferation glucan 1\,3-beta-glucosidase activity ->
glucan 1\,3-beta-glucosidase activity septum, extracellular ->
septum, extracellular YAP6
YMR148W NO SYMBOL
|YGR040W| KSS1 protein amino acid phosphorylation, cell cycle arrest, pseudohyphal growth, signal transduction during conjugation with cellular fusion ->
phosphorus metabolism, cell proliferation, cell organization and biogenesis, signal transduction, conjugation, protein metabolism, perception of external stimulus, sexual reproduction, response to abiotic stimulus MAP kinase activity ->
MAP kinase activity nucleus ->
nucleus ARG80, STP1
YJL172W CPS1 nitrogen metabolism, proteolysis and peptidolysis ->
nitrogen metabolism, catabolism, protein metabolism gly-X carboxypeptidase activity ->
gly-X carboxypeptidase activity vacuole (sensu Fungi) ->
cytoplasm PHO4
YGL191W COX13 aerobic respiration ->
energy pathways cytochrome c oxidase activity, enzyme regulator activity ->
cytochrome c oxidase activity, enzyme regulator activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane DOT6, HAP4, REB1, RGT1
|YJL158C| CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
YPR193C HPA2 histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism histone acetyltransferase activity ->
histone acetyltransferase activity cytoplasm ->
cytoplasm
|YKR096W| NO SYMBOL
Main: cell organization and biogenesis (0.50) structural constituent of cell wall (0.12) cytoplasm (0.50) REB1 SKN7 (0.29)
Score: 0.32 0.00 0.29 0.095
P-value: 4.756E-02 (G-protein coupled receptor protein signaling pathway) 5.363E-01 (hydrolase activity) 3.748E-01 (external encapsulating structure) 8.698E-01 (SKN7)

m_cytokinesis_orfnum2SD_n11(1) AND m_nitrogen_and_sulphur_utilization_orfnum2SD_n4(1) => SimExpr(YGL191W) OR SimExpr(other) : 5 1

EXPR: (0.200) m_nitrogen_and_sulphur_utilization_orfnum2SD_n4 (P < 0.001) m_cytokinesis_orfnum2SD_n11 (P < 0.007)

ORF SYMBOL P F C TF
YGL006W PMC1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium-transporting ATPase activity ->
purine nucleotide binding, cation transporter activity, primary active transporter activity, hydrolase activity\, acting on acid anhydrides, metal ion transporter activity vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole SKN7
|YHR131C| NO SYMBOL PHO4
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme regulator activity NDD1, RFX1, SWI6
YGL191W COX13 aerobic respiration ->
energy pathways cytochrome c oxidase activity, enzyme regulator activity ->
heme-copper terminal oxidase activity, enzyme regulator activity, oxidoreductase activity\, acting on heme group of donors, primary active transporter activity, cation transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane DOT6, HAP4, REB1, RGT1
YKR059W TIF1 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FKH1, FKH2
YOR317W FAA1 N-terminal protein myristoylation, lipid metabolism, lipid transport ->
biosynthesis, lipid metabolism, transport, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
ligase activity\, forming carbon-sulfur bonds lipid particle ->
cytoplasm ASH1, CIN5, HSF1, INO4, RAP1
Main: biosynthesis (0.40) primary active transporter activity (0.40) cytoplasm (1.00) ABF1 (0.17)
Score: 0.20 0.20 1.00 0.000
P-value: 1.626E+00 (protein biosynthesis) 8.681E-02 (primary active transporter activity) 2.499E+00 (membrane) 9.846E-01 (ASH1)

m_cell_death_orfnum2SD_n22(1) AND ALPHA1(1) AND m_lipid_and_fatty-acid_transport_orfnum2SD_n7(1) => SimExpr(YKL190W) OR SimExpr(other) : 5 1

EXPR: (0.163) m_lipid_and_fatty-acid_transport_orfnum2SD_n7 (P < 0.001) m_cell_death_orfnum2SD_n22 (P < 0.000) ALPHA1 (P < 0.000)

m_cell_death_orfnum2SD_n22(1) AND SFF(1) AND m_lipid_and_fatty-acid_transport_orfnum2SD_n7(1) => SimExpr(YKL190W) OR SimExpr(other) : 5 2

EXPR: (0.190) SFF (P < 0.000) m_lipid_and_fatty-acid_transport_orfnum2SD_n7 (P < 0.001) m_cell_death_orfnum2SD_n22 (P < 0.000)

ALPHA1(1) AND m_lipid_and_fatty-acid_transport_orfnum2SD_n11(1) AND CCA(1) => SimExpr(YKL190W) OR SimExpr(other) : 5 2

EXPR: (0.196) CCA (P < 0.002) m_lipid_and_fatty-acid_transport_orfnum2SD_n11 (P < 0.001) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YLR328W| NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity CIN5, MSN1, ROX1
YML028W TSA1 response to oxidative stress, regulation of redox homeostasis ->
oxygen and reactive oxygen species metabolism, cell homeostasis, response to biotic stimulus thioredoxin peroxidase activity ->
thioredoxin peroxidase activity cytoplasm ->
cytoplasm MBP1, NDD1, SKN7, YAP1
|YDR160W| SSY1 chemosensory perception ->
perception of external stimulus, response to abiotic stimulus amino acid binding ->
amino acid binding plasma membrane ->
plasma membrane GLN3, HAP5, SKN7
YPL100W MAI1 vacuolar protein processing/maturation ->
cell organization and biogenesis, protein metabolism, transport vacuolar membrane (sensu Fungi), cytosol ->
cytoplasm, storage vacuole
YIL069C RPS24B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, INO2, MCM1, RAP1
YDR276C PMP3 cation transport ->
transport plasma membrane ->
plasma membrane GAT1
YKL190W CNB1 cell ion homeostasis, cell wall organization and biogenesis, adaptation to pheromone during conjugation with cellular fusion ->
cell homeostasis, cell organization and biogenesis, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus calcium-dependent protein serine/threonine phosphatase activity ->
calcium-dependent protein serine/threonine phosphatase activity cytoplasm ->
cytoplasm ABF1
Main: cell organization and biogenesis (0.29) nicotinamide-nucleotide adenylyltransferase activity (0.20) cytoplasm (0.67) SKN7 (0.33)
Score: 0.24 0.00 0.47 0.067
P-value: 1.640E-01 (perception of chemical substance) 2.414E+00 (enzyme activity) 5.633E-01 (plasma membrane) 3.852E-01 (SKN7)

m_lysosomal_and_vacuolar_degradation_orfnum2SD_n8(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) => SimExpr(YKL190W) OR SimExpr(other) : 5 1

EXPR: (0.196) m_lysosomal_and_vacuolar_degradation_orfnum2SD_n8 (P < 0.011) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.001)

ORF SYMBOL P F C TF
YOR003W YSP3 protein catabolism ->
protein catabolism peptidase activity ->
peptidase activity
YGL080W NO SYMBOL USV1
YKL028W TFA1 transcription initiation from Pol II promoter ->
transcription\, DNA-dependent general RNA polymerase II transcription factor activity ->
general RNA polymerase II transcription factor activity transcription factor TFIIE complex ->
nucleus ABF1, CIN5
|YKL125W| RRN3 transcription from Pol I promoter ->
transcription\, DNA-dependent RNA polymerase I transcription factor activity ->
RNA polymerase I transcription factor activity RNA polymerase I transcription factor complex ->
nucleus
YJL172W CPS1 nitrogen metabolism, proteolysis and peptidolysis ->
nitrogen metabolism, protein catabolism gly-X carboxypeptidase activity ->
peptidase activity vacuole (sensu Fungi) ->
cytoplasm PHO4
YKL190W CNB1 cell ion homeostasis, cell wall organization and biogenesis, adaptation to pheromone during conjugation with cellular fusion ->
cell ion homeostasis, cell wall organization and biogenesis, conjugation with cellular fusion, perception of chemical substance, sensory perception calcium-dependent protein serine/threonine phosphatase activity ->
hydrolase activity\, acting on ester bonds cytoplasm ->
cytoplasm ABF1
Main: transcription\, DNA-dependent (0.40) peptidase activity (0.40) cytoplasm (0.50) ABF1 (0.50)
Score: 0.20 0.10 0.33 0.167
P-value: 2.259E-01 (protein catabolism) 7.584E-02 (peptidase activity) 9.626E-02 (transcription factor complex) 2.373E-01 (ABF1)

m_regulation_of_nucleotide_metabolism_orfnum2SD_n5(1) AND SCB(1) => SimExpr(YKL190W) OR SimExpr(other) : 8 3

EXPR: (0.231) m_regulation_of_nucleotide_metabolism_orfnum2SD_n5 (P < 0.074) SCB (P < 0.001)

ORF SYMBOL P F C TF
YMR272C SCS7 fatty acid metabolism ->
lipid metabolism, organic acid metabolism oxidoreductase activity ->
oxidoreductase activity endoplasmic reticulum ->
cytoplasm IXR1, SUM1
YKR042W UTH1 mitochondrion organization and biogenesis ->
cell organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
|YPR134W| MSS18 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism MSS11
|YPR125W| NO SYMBOL MAC1
YPL218W SAR1 ER to Golgi transport ->
transport, vesicle-mediated transport SAR small monomeric GTPase activity ->
guanyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides COPII vesicle coat ->
cytoplasm
|YLR310C| CDC25 RAS protein signal transduction, regulation of cell cycle, start control point of mitotic cell cycle ->
signal transduction, cell proliferation Ras guanyl-nucleotide exchange factor activity ->
guanyl nucleotide binding, small GTPase regulatory/interacting protein activity cytoplasm, plasma membrane ->
cytoplasm, plasma membrane CIN5, SIP4
YDR281C PHM6 PHO4, SUM1
YPL092W SSU1 sulfite transport ->
transport sulfite transporter activity ->
inorganic anion transporter activity plasma membrane ->
plasma membrane
YKL190W CNB1 cell ion homeostasis, cell wall organization and biogenesis, adaptation to pheromone during conjugation with cellular fusion ->
cell homeostasis, cell organization and biogenesis, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus calcium-dependent protein serine/threonine phosphatase activity ->
phosphoric ester hydrolase activity cytoplasm ->
cytoplasm ABF1
YKR013W PRY2 SWI4, SWI6
YPL221W BOP1 CBF1
Main: cell organization and biogenesis (0.29) guanyl nucleotide binding (0.40) cytoplasm (0.83) SWI4 SUM1 (0.22)
Score: 0.10 0.10 0.73 0.056
P-value: 5.539E+00 (transport) 2.489E-01 (guanyl nucleotide binding) 1.092E+00 (plasma membrane) 3.156E-01 (SUM1)

m_regulation_of_nucleotide_metabolism_orfnum2SD_n5(1) AND PDR(1) => SimExpr(YKL190W) OR SimExpr(other) : 6 2

EXPR: (0.208) m_regulation_of_nucleotide_metabolism_orfnum2SD_n5 (P < 0.023) PDR (P < 0.004)

ORF SYMBOL P F C TF
YMR272C SCS7 fatty acid metabolism ->
lipid metabolism, organic acid metabolism oxidoreductase activity ->
oxidoreductase activity endoplasmic reticulum ->
cytoplasm IXR1, SUM1
YKR042W UTH1 mitochondrion organization and biogenesis ->
cell organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
|YPR125W| NO SYMBOL MAC1
YML116W ATR1 multidrug transport ->
transport, response to abiotic stimulus multidrug efflux pump activity ->
multidrug efflux pump activity plasma membrane ->
plasma membrane CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
|YGR067C| NO SYMBOL ABF1, ASH1, RGM1
YDR281C PHM6 PHO4, SUM1
YGR008C STF2 response to dessication, ATP synthesis coupled proton transport ->
response to abiotic stimulus, transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane INO2
YKL190W CNB1 cell ion homeostasis, cell wall organization and biogenesis, adaptation to pheromone during conjugation with cellular fusion ->
cell homeostasis, cell organization and biogenesis, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus calcium-dependent protein serine/threonine phosphatase activity ->
calcium-dependent protein serine/threonine phosphatase activity cytoplasm ->
cytoplasm ABF1
Main: response to abiotic stimulus (0.60) oxidoreductase activity (0.33) cytoplasm (0.80) ABF1 ASH1 HSF1 FKH2 SUM1 (0.25)
Score: 0.40 0.00 0.60 0.143
P-value: 5.110E-02 (response to abiotic stimulus) 2.919E+00 (enzyme activity) 4.644E-01 (mitochondrial membrane) 5.554E-02 (ASH1)

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_amino-acid_biosynthesis_orfnum2SD_n9(1) => SimExpr(YDR085C) OR SimExpr(other) : 5 1

EXPR: (0.192) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.002) m_amino-acid_biosynthesis_orfnum2SD_n9 (P < 0.001)

ORF SYMBOL P F C TF
YDR085C AFR1 regulation of G-protein coupled receptor protein signaling pathway, signal transduction during conjugation with cellular fusion ->
regulation of G-protein coupled receptor protein signaling pathway, signal transduction during conjugation with cellular fusion receptor signaling protein activity ->
receptor signaling protein activity shmoo tip ->
site of polarized growth (sensu Fungi) FKH1, RLM1, SFL1
YDR359C VID21 ABF1
|YGR239C| PEX21 protein-peroxisome targeting ->
protein-peroxisome targeting protein binding, enzyme activator activity ->
protein binding, enzyme activator activity peroxisome, cytosol ->
cytoplasm MAL13, MET4, PUT3
YOR374W ALD4 ethanol metabolism ->
ethanol metabolism aldehyde dehydrogenase (NAD+) activity ->
aldehyde dehydrogenase (NAD+) activity mitochondrion ->
cytoplasm RAP1
YJL021C NO SYMBOL GAT1, SIG1
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
trehalose phosphatase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
Main: response to stress (0.25) trehalose phosphatase activity (0.25) cytoplasm (0.50) ABF1 (0.20)
Score: 0.00 0.00 0.17 0.000
P-value: 4.571E+00 (metabolism) 2.725E+00 (enzyme activity) 4.731E+00 (cytoplasm) 4.060E-01 (PUT3)

m_cell_death_orfnum2SD_n22(1) AND m_other_pheromone_response_activities_orfnum2SD_n12(1) AND m_other_mrna-transcription_activities_orfnum2SD_n20(1) => SimExpr(YLR156W) OR SimExpr(other) : 5 2

EXPR: (0.205) m_other_mrna-transcription_activities_orfnum2SD_n20 (P < 0.000) m_cell_death_orfnum2SD_n22 (P < 0.000) m_other_pheromone_response_activities_orfnum2SD_n12 (P < 0.000)

ORF SYMBOL P F C TF
YLR161W NO SYMBOL
YLR156W NO SYMBOL CBF1
|YOL012C| HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
YLR159W NO SYMBOL
YOR349W CIN1 post-chaperonin tubulin folding pathway, beta-tubulin folding ->
cell organization and biogenesis co-chaperone activity ->
co-chaperone activity microtubule ->
cytoplasm SWI5
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MTH1
|YOR130C| ORT1 arginine biosynthesis, nuclear migration (sensu Saccharomyces) ->
amine metabolism, cell organization and biogenesis, cell proliferation, cell cycle, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ornithine transporter activity ->
ornithine transporter activity mitochondrial membrane ->
cytoplasm GCN4
Main: cell organization and biogenesis (0.75) chromatin binding (0.25) cytoplasm (0.67) SWI4 (0.20)
Score: 0.50 0.00 0.33 0.000
P-value: 1.031E-01 (microtubule cytoskeleton organization and biogenesis) 2.000E+00 4.869E+00 (cytoplasm) 4.347E-01 (CBF1)

m_other_pheromone_response_activities_orfnum2SD_n12(1) AND m_other_mrna-transcription_activities_orfnum2SD_n20(1) AND CSRE(1) => SimExpr(YLR156W) OR SimExpr(other) : 5 1

EXPR: (0.202) m_other_mrna-transcription_activities_orfnum2SD_n20 (P < 0.000) CSRE (P < 0.000) m_other_pheromone_response_activities_orfnum2SD_n12 (P < 0.000)

ORF SYMBOL P F C TF
YLR161W NO SYMBOL
YLR156W NO SYMBOL CBF1
|YML073C| RPL6A protein biosynthesis, ribosomal large subunit assembly and maintenance ->
macromolecule biosynthesis, cytoplasm organization and biogenesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, YAP5
YLR159W NO SYMBOL
YOR349W CIN1 post-chaperonin tubulin folding pathway, beta-tubulin folding ->
cytoplasm organization and biogenesis co-chaperone activity ->
co-chaperone activity microtubule ->
cytoplasm SWI5
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphate metabolism, macromolecule catabolism, protein modification, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MTH1
Main: cytoplasm organization and biogenesis (0.67) RNA binding (0.33) cytoplasm (1.00) MTH1 (0.25)
Score: 0.67 0.00 1.00 0.000
P-value: 2.720E+00 (cytoplasm organization and biogenesis) 2.000E+00 4.731E+00 (cytoplasm) 5.249E-01 (CBF1)

m_amino-acid_metabolism_orfnum2SD_n14(1) AND m_anion_transporters_orfnum2SD_n17(1) => SimExpr(YMR135C) OR SimExpr(other) : 5 2

EXPR: (0.234) m_anion_transporters_orfnum2SD_n17 (P < 0.000) m_amino-acid_metabolism_orfnum2SD_n14 (P < 0.061)

ORF SYMBOL P F C TF
YOR348C PUT4 neutral amino acid transport ->
amine/polyamine transport, organic acid transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid-polyamine transporter activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YNL052W COX5A aerobic respiration ->
energy derivation by oxidation of organic compounds cytochrome c oxidase activity ->
heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors\, oxygen as acceptor, primary active transporter activity, hydrogen ion transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
|YOR173W| DCS2 CAD1
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine biosynthesis, cytoplasm organization and biogenesis, amine metabolism, amino acid and derivative metabolism, carboxylic acid metabolism ketol-acid reductoisomerase activity ->
ketol-acid reductoisomerase activity mitochondrion ->
cytoplasm GCN4, MET4
|YMR042W| ARG80 positive regulation of transcription from Pol II promoter, arginine metabolism ->
amine metabolism, urea cycle intermediate metabolism, transcription, amino acid and derivative metabolism, carboxylic acid metabolism DNA binding, specific RNA polymerase II transcription factor activity ->
DNA binding, specific RNA polymerase II transcription factor activity nucleus ->
nucleus RME1
YGR055W MUP1 sulfur amino acid transport ->
amine/polyamine transport, organic acid transport L-methionine porter activity ->
amino acid-polyamine transporter activity, L-amino acid transporter activity, neutral amino acid transporter activity, sulfur amino acid transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane DAL81, INO4, MET4, STP1
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol biosynthesis, regulation of biosynthesis, monosaccharide metabolism, carbohydrate metabolism, negative regulation of metabolism, carbohydrate biosynthesis, energy derivation by oxidation of organic compounds, regulation of metabolism ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: amine/polyamine transport (0.33) amino acid-polyamine transporter activity (0.40) cytoplasm (0.40) DAL81 MET4 INO4 (0.29)
Score: 0.20 0.10 0.20 0.095
P-value: 1.784E-02 (amino acid transport) 2.196E-03 (amino acid-polyamine transporter activity) 5.633E-01 (plasma membrane) 8.846E-02 (MET4)

m_allantoin_and_allantoate_transporters_orfnum2SD_n18(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YML088W) OR SimExpr(other) : 5 2

EXPR: (0.201) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n18 (P < 0.000)

ORF SYMBOL P F C TF
YKL210W UBA1 ubiquitin cycle ->
catabolism, protein metabolism ubiquitin activating enzyme activity ->
ubiquitin activating enzyme activity nucleus, cytoplasm ->
nucleus, cytoplasm SKO1
YNL069C RPL16B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
|YPL228W| CET1 mRNA capping ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism polynucleotide 5'-phosphatase activity ->
polynucleotide 5'-phosphatase activity nucleus ->
nucleus ABF1
YGR234W YHB1 response to stress ->
response to stress ACE2, CAD1, CIN5, DAL82, HAP2, HAP3, SWI5, YAP1
YML088W UFO1 response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity HAP4, RAP1, SKN7
|YJR002W| MPP10 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YGL009C LEU1 leucine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis 3-isopropylmalate dehydratase activity ->
3-isopropylmalate dehydratase activity cytosol ->
cytoplasm LEU3
Main: protein metabolism (0.43) RNA binding (0.20) cytoplasm (0.60) RAP1 (0.33)
Score: 0.24 0.00 0.70 0.067
P-value: 2.621E-01 (ubiquitin-dependent protein catabolism) 1.628E+00 (enzyme activity) 1.325E+00 (ribonucleoprotein complex) 1.000E+00

m_cell_death_orfnum2SD_n22(1) AND m_amino-acid_biosynthesis_orfnum2SD_n9(1) => SimExpr(YDR047W) OR SimExpr(other) : 9 2

EXPR: (0.233) m_cell_death_orfnum2SD_n22 (P < 0.000) m_amino-acid_biosynthesis_orfnum2SD_n9 (P < 0.020)

m_cell_death_orfnum2SD_n22(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn(1) AND m_amino-acid_biosynthesis_orfnum2SD_n9(1) => SimExpr(YDR047W) : 5

EXPR: (0.185) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn (P < 0.000) m_cell_death_orfnum2SD_n22 (P < 0.000) m_amino-acid_biosynthesis_orfnum2SD_n9 (P < 0.011)

m_RPE17(1) AND LYS14(1) => SimExpr(YKL180W) OR SimExpr(other) : 5 2

RAP1(1) AND m_pentose-phosphate_pathway_orfnum2SD_n5(1) => SimExpr(YKL180W) OR SimExpr(other) : 6 1

RAP1(1) AND m_drug_transporters_orfnum2SD_n10(1) => SimExpr(YKL180W) OR SimExpr(other) : 6 2

EXPR: (0.178) m_drug_transporters_orfnum2SD_n10 (P < 0.000) RAP1 (P < 0.190)

RAP1(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn(1) => SimExpr(YKL180W) OR SimExpr(other) : 6 1

EXPR: (0.134) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn (P < 0.000) RAP1 (P < 0.025)

RAP1(1) AND m_nitrogen_and_sulphur_transport_orfnum2SD_n9(1) => SimExpr(YKL180W) OR SimExpr(other) : 7 2

EXPR: (0.177) RAP1 (P < 0.145) m_nitrogen_and_sulphur_transport_orfnum2SD_n9 (P < 0.000)

m_pentose-phosphate_pathway_orfnum2SD_n5(1) AND m_RPE6(1) => SimExpr(YKL180W) : 6

m_RPE57(1) AND m_RPE8(1) => SimExpr(YKL180W) : 5

m_RPE57(1) AND m_RPE6(1) => SimExpr(YKL180W) : 7

RAP1(1) AND m_RPE6(1) => SimExpr(YKL180W) : 9

RAP1(1) AND m_RPE57(1) => SimExpr(YKL180W) : 8

RAP1(1) AND m_RPE8(1) => SimExpr(YKL180W) : 9

m_RPE6(1) AND m_RPE8(1) => SimExpr(YKL180W) : 8

RAP1(1) AND m_RPE17(1) => SimExpr(YKL180W) : 5

m_RPE8(1) AND m_RPE17(1) => SimExpr(YKL180W) : 5

m_RPE6(1) AND m_RPE21(1) => SimExpr(YKL180W) : 5

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_RRSE3(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) AND ALPHA1'(1) => SimExpr(YNL040W) OR SimExpr(other) : 5 2

EXPR: (0.214) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n13 (P < 0.000) m_RRSE3 (P < 0.000) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
YIL121W QDR2 PHO4, RAP1, SWI4
YNL134C NO SYMBOL CAD1, HAL9, HSF1, NDD1, YAP1
YFL042C NO SYMBOL MAL13
|YGL211W| NO SYMBOL
YKL157W APE2 peptide metabolism ->
peptide metabolism leucyl aminopeptidase activity ->
leucyl aminopeptidase activity cytoplasm, periplasmic space (sensu Fungi) ->
cytoplasm, periplasmic space (sensu Fungi) CIN5, FKH1, FKH2
|YGL133W| ITC1 chromatin modeling, negative regulation of transcription from Pol II promoter by pheromones ->
chromatin modeling, negative regulation of transcription from Pol II promoter by pheromones nucleus ->
nucleus ACE2, HAP3, PHO4, RPH1, RTG1
YNL040W NO SYMBOL FZF1, GCR2, RTG3, YAP7
Main: chromatin modeling (0.50) leucyl aminopeptidase activity (1.00) cytoplasm (0.50) PHO4 (0.33)
Score: 0.00 0.00 0.00 0.067
P-value: 3.979E+00 (metabolism) 0.000E+00 4.000E+00 (intracellular) 2.446E-01 (PHO4)

m_cell_death_orfnum2SD_n22(1) AND m_ion_transporters_orfnum2SD_n14(1) => SimExpr(YOL120C) OR SimExpr(other) : 5 2

EXPR: (0.173) m_cell_death_orfnum2SD_n22 (P < 0.000) m_ion_transporters_orfnum2SD_n14 (P < 0.008)

m_cell_death_orfnum2SD_n22(1) AND RAP1(1) => SimExpr(YOL120C) OR SimExpr(other) : 8 1

RAP1(1) AND mRRPE(1) => SimExpr(YOL120C) OR SimExpr(other) : 7 3

EXPR: (0.160) mRRPE (P < 0.000) RAP1 (P < 0.103)

RAP1(1) AND MCM1'(1) => SimExpr(YOL120C) OR SimExpr(other) : 18 2

RAP1(1) AND m_MERE17(1) => SimExpr(YOL120C) OR SimExpr(other) : 5 1

RAP1(1) AND m_RPE58(1) => SimExpr(YOL120C) : 6

RAP1(1) AND PDR(1) => SimExpr(YLR441C) OR SimExpr(other) : 5 1

m_cell_death_orfnum2SD_n22(1) AND RAP1(1) => SimExpr(YLR441C) OR SimExpr(other) : 8 1

m_RPE8(1) AND m_RPE34(1) => SimExpr(YGR214W) OR SimExpr(other) : 6 3

EXPR: (0.189) m_RPE8 (P < 0.013) m_RPE34 (P < 0.089)

m_organization_of_cytoplasm_orfnum2SD_n27(1) => SimExpr(YGR214W) OR SimExpr(other) : 6 3

m_RPE6(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YGR214W) OR SimExpr(other) : 8 2

EXPR: (0.162) m_amino-acid_transport_orfnum2SD_n20 (P < 0.000) m_RPE6 (P < 0.090)

RAP1(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YGR214W) OR SimExpr(other) : 8 3

EXPR: (0.178) RAP1 (P < 0.059) m_amino-acid_transport_orfnum2SD_n20 (P < 0.000)

m_cell_death_orfnum2SD_n22(1) AND m_RPE6(1) => SimExpr(YGR214W) OR SimExpr(other) : 6 3

EXPR: (0.175) m_cell_death_orfnum2SD_n22 (P < 0.000) m_RPE6 (P < 0.199)

m_RPE6(1) AND CSRE(1) => SimExpr(YGR214W) OR SimExpr(other) : 10 1

RAP1(1) AND m_MERE17(1) => SimExpr(YGR214W) OR SimExpr(other) : 5 1

m_amino-acid_transport_orfnum2SD_n20(1) AND m_RPE34(1) => SimExpr(YGR214W) OR SimExpr(other) : 6 2

EXPR: (0.166) m_amino-acid_transport_orfnum2SD_n20 (P < 0.000) m_RPE34 (P < 0.025)

m_RPE6(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YGR214W) : 7

EXPR: (0.133) m_cell_death_orfnum2SD_n8 (P < 0.000) m_RPE6 (P < 0.031)

RAP1(1) AND m_RPE8(1) => SimExpr(YGR214W) : 9

m_RPE6(1) AND m_RPE34(1) => SimExpr(YGR214W) : 6

RAP1(1) AND m_RPE6(1) => SimExpr(YGR214W) : 9

RAP1(1) AND m_RPE34(1) => SimExpr(YGR214W) : 8

m_RPE6(1) AND m_RPE8(1) => SimExpr(YGR214W) : 8

m_RPE72(1) AND m_RPE8(1) => SimExpr(YGR214W) : 5

m_organization_of_cytoplasm_orfnum2SD_n27(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YGR214W) : 5

RAP1(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YGR214W) : 5

RAP1(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YGR214W) : 8

SFF(1) AND CSRE(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YLR185W) OR SimExpr(other) : 13 2

EXPR: (0.184) SFF (P < 0.000) CSRE (P < 0.000) m_cell_death_orfnum2SD_n16 (P < 0.000)

SFF'(1) AND CSRE(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YLR185W) OR SimExpr(other) : 15 4

EXPR: (0.197) SFF' (P < 0.000) CSRE (P < 0.000) m_cell_death_orfnum2SD_n16 (P < 0.000)

SFF(1) AND m_MERE4(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YLR185W) OR SimExpr(other) : 7 3

EXPR: (0.210) SFF (P < 0.000) m_cell_death_orfnum2SD_n16 (P < 0.004) m_MERE4 (P < 0.001)

ORF SYMBOL P F C TF
YNR018W NO SYMBOL ACE2, FZF1, IME4, MBP1, NDD1, RAP1, SFP1, SKN7, SWI4, SWI5, YJL206C
YNL162W RPL42A protein biosynthesis ->
macromolecule biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1, YAP5
YOR382W FIT2 siderochrome transport ->
siderochrome transport cell wall (sensu Fungi) ->
cell wall
YLR205C HMX1 iron ion homeostasis ->
cell ion homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy derivation by oxidation of organic compounds, electron transport, phosphate metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, membrane HAP4, MBP1
|YFR015C| GSY1 glycogen metabolism ->
polysaccharide metabolism, energy derivation by oxidation of organic compounds glycogen (starch) synthase activity ->
glycogen (starch) synthase activity INO4
|YPL111W| CAR1 arginine catabolism to ornithine ->
amine catabolism, amine metabolism, urea cycle intermediate metabolism, amino acid and derivative metabolism, carboxylic acid metabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
|YFL030W| AGX1 glyoxylate cycle ->
aldehyde metabolism, carbohydrate metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds alanine-glyoxylate aminotransferase activity ->
alanine-glyoxylate aminotransferase activity
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cellular morphogenesis, sporulation (sensu Fungi), cell surface receptor linked signal transduction, intracellular signaling cascade RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
membrane ACE2, SKN7
YLR185W RPL37A protein biosynthesis ->
macromolecule biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1, RGM1, YAP5
Main: energy derivation by oxidation of organic compounds (0.33) structural constituent of ribosome (0.25) cytoplasm (0.57) SKN7 RAP1 (0.38)
Score: 0.14 0.04 0.43 0.250
P-value: 1.579E-01 (energy pathways) 1.132E+00 (structural constituent of ribosome) 2.637E-01 (cytosolic large ribosomal subunit (sensu Eukarya)) 9.514E-02 (SKN7)

CSRE(1) AND m_RPE34(1) => SimExpr(YLR185W) OR SimExpr(other) : 8 2

m_cell_death_orfnum2SD_n22(1) AND m_RPE34(1) => SimExpr(YLR185W) OR SimExpr(other) : 7 3

m_homeostasis_of_metal_ions_orfnum2SD_n20(1) AND m_RPE34(1) => SimExpr(YLR185W) OR SimExpr(other) : 5 2

m_RPE69(1) AND m_RPE34(1) => SimExpr(YLR185W) : 5

EXPR: (0.110) m_RPE69 (P < 0.020) m_RPE34 (P < 0.012)

m_RPE57(1) AND m_RPE34(1) => SimExpr(YLR185W) : 5

MCM1'(1) AND SFF(1) AND HAP234(1) => SimExpr(YPR035W) OR SimExpr(other) : 5 2

EXPR: (0.189) SFF (P < 0.000) HAP234 (P < 0.035) MCM1' (P < 0.000)

m_anion_transporters_orfnum2SD_n17(1) AND HAP234(1) => SimExpr(YPR035W) OR SimExpr(other) : 5 1

PAC(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YPR010C) OR SimExpr(other) : 28 13

EXPR: (0.226) mRRPE (P < 0.000) PAC (P < 0.000) ALPHA1' (P < 0.000)

m_cell_death_orfnum2SD_n22(1) AND m_ion_transporters_orfnum2SD_n14(1) => SimExpr(YML126C) OR SimExpr(other) : 5 2

RAP1(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) => SimExpr(YMR193W) OR SimExpr(other) : 5 2

EXPR: (0.200) RAP1 (P < 0.009) m_other_nucleotide-metabolism_activities_orfnum2SD_n17 (P < 0.004)

m_cell_death_orfnum2SD_n22(1) AND RAP1(1) => SimExpr(YMR193W) OR SimExpr(other) : 6 3

m_drug_transporters_orfnum2SD_n10(1) AND m_nitrogen_and_sulphur_transport_orfnum2SD_n9(1) => SimExpr(YMR193W) OR SimExpr(other) : 6 3

EXPR: (0.198) m_drug_transporters_orfnum2SD_n10 (P < 0.000) m_nitrogen_and_sulphur_transport_orfnum2SD_n9 (P < 0.000)

PDR(1) AND m_fermentation_orfnum2SD_n14(1) => SimExpr(YMR272C) OR SimExpr(other) : 5 2

EXPR: (0.223) PDR (P < 0.008) m_fermentation_orfnum2SD_n14 (P < 0.013)

ORF SYMBOL P F C TF
YMR272C SCS7 fatty acid metabolism ->
lipid metabolism, carboxylic acid metabolism oxidoreductase activity ->
oxidoreductase activity endoplasmic reticulum ->
endoplasmic reticulum IXR1, SUM1
YPL250C ICY2 HSF1, MET4
YDR380W ARO10 leucine catabolism ->
amine catabolism, amine metabolism, amino acid and derivative metabolism, carboxylic acid metabolism carboxy-lyase activity, pyruvate decarboxylase activity ->
carboxy-lyase activity, pyruvate decarboxylase activity ARO80, MTH1
|YJR155W| AAD10 aldehyde metabolism ->
aldehyde metabolism oxidoreductase activity ->
oxidoreductase activity
YLR412W NO SYMBOL
|YNL289W| PCL1 cell cycle ->
cell cycle cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex ASH1, MBP1, MCM1, STB1, STE12, SWI4, SWI6
YAL061W NO SYMBOL
Main: carboxylic acid metabolism (0.50) oxidoreductase activity (0.50) endoplasmic reticulum (0.50) SWI4 (0.25)
Score: 0.17 0.17 0.00 0.000
P-value: 3.810E-01 (organic acid metabolism) 3.837E-01 (oxidoreductase activity) 4.000E+00 (intracellular) 8.743E-01 (ASH1)

BAS1(1) AND MCB(1) => SimExpr(YHR110W) OR SimExpr(other) : 5 1

EXPR: (0.167) MCB (P < 0.006) BAS1 (P < 0.000)

ORF SYMBOL P F C TF
YHR110W ERP5 secretory pathway ->
transport integral to membrane ->
integral to membrane DOT6, RGT1
YJR154W NO SYMBOL CIN5, GCN4, RIM101
YGR109C CLB6 regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis ->
cell proliferation, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity MBP1, STB1, SWI4, SWI6
|YIL066C| RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity cytoplasm ->
cytoplasm RFX1, STB1
YPR185W APG13 protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
YJL181W NO SYMBOL
Main: cell proliferation (0.50) cyclin-dependent protein kinase\, regulator activity (0.33) extrinsic to membrane (0.33) SWI6 STB1 (0.40)
Score: 0.33 0.00 0.00 0.200
P-value: 1.640E-01 (DNA replication) 2.725E+00 (enzyme activity) 1.666E+00 (membrane) 2.568E-02 (STB1)

m_RPE57(1) AND m_LFTE17(1) => SimExpr(YNL096C) OR SimExpr(other) : 6 2

RAP1(1) AND m_other_mrna-transcription_activities_orfnum2SD_n20(1) => SimExpr(YNL096C) OR SimExpr(other) : 8 2

EXPR: (0.174) m_other_mrna-transcription_activities_orfnum2SD_n20 (P < 0.000) RAP1 (P < 0.041)

m_pentose-phosphate_pathway_orfnum2SD_n23(1) AND m_cytok9(1) => SimExpr(YNL096C) OR SimExpr(other) : 6 2

EXPR: (0.226) m_cytok9 (P < 0.009) m_pentose-phosphate_pathway_orfnum2SD_n23 (P < 0.003)

ORF SYMBOL P F C TF
|YHL024W| RIM4 sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination ->
sporulation, M phase, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation RNA binding ->
RNA binding cytoplasm ->
cytoplasm FKH2, PHD1
YLR342W FKS1 beta-1\,3 glucan biosynthesis, cell wall organization and biogenesis ->
biosynthesis, cell organization and biogenesis, carbohydrate metabolism 1\,3-beta-glucan synthase activity ->
1\,3-beta-glucan synthase activity actin cap (sensu Saccharomyces), 1\,3-beta-glucan synthase complex ->
cell cortex, plasma membrane, cytoplasm MBP1, RLM1, STB1, SWI4
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YNL096C RPS7B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, SFP1
YDR341C NO SYMBOL GCN4, ZMS1
YFL008W SMC1 mitotic chromosome segregation ->
cell proliferation, cell cycle DNA secondary structure binding, AT DNA binding, double-stranded DNA binding, ATPase activity ->
DNA secondary structure binding, AT DNA binding, double-stranded DNA binding, ATPase activity nuclear cohesin complex ->
chromosome, nucleus MBP1
YNL157W NO SYMBOL
|YMR173W| DDR48 DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism CAD1, CIN5, PHD1, SKN7
Main: biosynthesis (0.33) RNA binding (0.20) cytoplasm (0.80) PHD1 MBP1 (0.29)
Score: 0.27 0.00 0.60 0.095
P-value: 1.091E+00 (carbohydrate metabolism) 2.059E+00 (nucleic acid binding) 3.922E+00 (cytoplasm) 4.452E-01 (PHD1)

m_osmosensing_orfnum2SD_n6(1) AND RAP1(1) => SimExpr(YNL096C) OR SimExpr(other) : 6 2

EXPR: (0.175) RAP1 (P < 0.060) m_osmosensing_orfnum2SD_n6 (P < 0.000)

RAP1(1) AND PDR(1) => SimExpr(YNL096C) OR SimExpr(other) : 5 1

RAP1(1) AND m_RPE58(1) => SimExpr(YNL096C) : 6

RAP1(1) AND m_RPE57(1) => SimExpr(YNL096C) : 8

RAP1(1) AND m_LFTE17(1) => SimExpr(YNL096C) : 7

m_anion_transporters_orfnum2SD_n15(1) AND m_cytokinesis_orfnum2SD_n11(1) => SimExpr(YGR124W) OR SimExpr(other) : 5 2

EXPR: (0.204) m_anion_transporters_orfnum2SD_n15 (P < 0.000) m_cytokinesis_orfnum2SD_n11 (P < 0.005)

ORF SYMBOL P F C TF
YGR124W ASN2 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
carbon-nitrogen ligase activity\, with glutamine as amido-N-donor ASH1, ROX1
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
nucleotidyltransferase activity
YML126C ERG13 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism hydroxymethylglutaryl-CoA synthase activity ->
oxo-acid-lyase activity endoplasmic reticulum, mitochondrion ->
cytoplasm
|YHR002W| LEU5 coenzyme A transport ->
transport coenzyme A transporter activity ->
coenzyme A transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane HAP4, SKN7, SWI6
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
oxo-acid-lyase activity, carboxy-lyase activity CRZ1
YGR279C SCW4 conjugation with cellular fusion ->
conjugation, sexual reproduction glucosidase activity ->
hydrolase activity\, hydrolyzing O-glycosyl compounds cell wall (sensu Fungi) ->
cell wall ASH1, IXR1, PHD1, SWI4
|YOR317W| FAA1 N-terminal protein myristoylation, lipid metabolism, lipid transport ->
biosynthesis, lipid metabolism, transport, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
fatty-acid ligase activity lipid particle ->
cytoplasm ASH1, CIN5, HSF1, INO4, RAP1
Main: biosynthesis (0.71) oxo-acid-lyase activity (0.29) cytoplasm (0.75) ASH1 (0.60)
Score: 0.52 0.05 0.50 0.300
P-value: 1.340E-01 (biosynthesis) 4.735E-03 (oxo-acid-lyase activity) 1.397E+00 (mitochondrion) 3.744E-04 (ASH1)

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) => SimExpr(YKL096W) OR SimExpr(other) : 6 2

EXPR: (0.203) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.000) m_other_morphogenetic_activities_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YML067C ERV41 ER to Golgi transport ->
transport, vesicle-mediated transport integral to Golgi membrane, endoplasmic reticulum membrane\, intrinsic protein, COPII-coated vesicle ->
cytoplasm, cytoplasmic vesicle, integral to membrane, endomembrane system
YIL021W RPB3 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase II\, core complex ->
nucleus
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane
|YIL052C| RPL34B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex RME1
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
|YAL045C| NO SYMBOL BAS1, YFL044C
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
YDL128W VCX1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cytoplasm, vacuole MAC1, STE12
Main: transport (0.43) structural constituent of cell wall (0.17) cytoplasm (0.43) SMP1 STE12 (0.40)
Score: 0.24 0.00 0.19 0.200
P-value: 2.343E+00 (transport) 2.475E-01 (carrier activity) 1.893E+00 (membrane) 7.834E-02 (SMP1)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_g-proteins_orfnum2SD_n12(1) AND STRE(1) => SimExpr(YPL154C) OR SimExpr(other) : 5 2

EXPR: (0.241) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.005) STRE (P < 0.026)

ORF SYMBOL P F C TF
|YFL036W| RPO41 mitochondrial genome maintenance, transcription from mitochondrial promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity mitochondrial matrix ->
cytoplasm
|YOR092W| ECM3 cell wall organization and biogenesis ->
cell organization and biogenesis ATPase activity ->
ATPase activity STE12, YAP1
YNL200C NO SYMBOL
YKL117W SBA1 protein folding ->
protein metabolism co-chaperone activity ->
co-chaperone activity nucleus, cytoplasm ->
nucleus, cytoplasm
YGR067C NO SYMBOL ABF1, ASH1, RGM1
YJL052W TDH1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity cytosol, lipid particle, cell wall ->
cytoplasm, cell wall MAC1
YPL154C PEP4 microautophagy, vacuolar protein catabolism, sporulation, cellular response to starvation ->
autophagy, catabolism, sporulation, response to extracellular stimulus, protein metabolism, response to biotic stimulus saccharopepsin activity, endopeptidase activity ->
saccharopepsin activity, endopeptidase activity vacuole (sensu Fungi) ->
cytoplasm
Main: cell organization and biogenesis (0.40) co-chaperone activity (0.20) cytoplasm (1.00) ABF1 (0.33)
Score: 0.30 0.00 1.00 0.000
P-value: 1.034E+00 (catabolism) 1.611E+00 (hydrolase activity) 3.294E+00 (cytoplasm) 4.035E-01 (ASH1)

m_phosphate_transport_orfnum2SD_n18(1) AND m_phosphate_metabolism_orfnum2SD_n16(1) => SimExpr(YML123C) OR SimExpr(other) : 5 2

EXPR: (0.206) m_phosphate_transport_orfnum2SD_n18 (P < 0.003) m_phosphate_metabolism_orfnum2SD_n16 (P < 0.012)

ORF SYMBOL P F C TF
YOR343C NO SYMBOL DIG1, RAP1, STE12
YLR406C RPL31B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, FKH1, MTH1, RAP1
|YNR064C| NO SYMBOL
|YLR460C| NO SYMBOL CIN5, HAL9, YAP1
YLR354C TAL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transaldolase activity ->
transaldolase activity cytoplasm ->
cytoplasm MBP1
YML123C PHO84 phosphate transport ->
transport inorganic phosphate transporter activity ->
inorganic phosphate transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane HIR2
YAL007C ERP2 ER to Golgi transport ->
transport, vesicle-mediated transport COPII-coated vesicle ->
cytoplasm
Main: transport (0.50) transaldolase activity (0.33) cytoplasm (0.75) RAP1 (0.40)
Score: 0.17 0.00 0.50 0.100
P-value: 3.053E+00 (transport) 2.000E+00 4.385E+00 (cytoplasm) 6.888E-01 (RAP1)

m_pentose-phosphate_pathway_orfnum2SD_n23(1) AND m_phosphate_metabolism_orfnum2SD_n16(1) => SimExpr(YML123C) : 5

EXPR: (0.155) m_phosphate_metabolism_orfnum2SD_n16 (P < 0.003) m_pentose-phosphate_pathway_orfnum2SD_n23 (P < 0.000)

ORF SYMBOL P F C TF
YOR343C NO SYMBOL DIG1, RAP1, STE12
YOR312C RPL20B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, FKH2, GAT3, RAP1
YLR354C TAL1 pentose-phosphate shunt ->
pentose-phosphate shunt transaldolase activity ->
transaldolase activity cytoplasm ->
cytoplasm MBP1
YML123C PHO84 phosphate transport ->
phosphate transport inorganic phosphate transporter activity ->
inorganic phosphate transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane HIR2
YOR095C RKI1 pentose-phosphate shunt ->
pentose-phosphate shunt ribose-5-phosphate isomerase activity ->
ribose-5-phosphate isomerase activity FHL1, FKH2, RAP1
Main: pentose-phosphate shunt (0.50) transaldolase activity (0.25) cytoplasm (0.67) RAP1 (0.60)
Score: 0.17 0.00 0.33 0.300
P-value: 1.389E-03 (pentose-phosphate shunt) 2.509E+00 (enzyme activity) 4.460E+00 (cytoplasm) 1.593E-02 (RAP1)

m_osmosensing_orfnum2SD_n6(1) AND PHO(1) => SimExpr(YOR270C) OR SimExpr(other) : 6 2

EXPR: (0.215) PHO (P < 0.002) m_osmosensing_orfnum2SD_n6 (P < 0.002)

ORF SYMBOL P F C TF
|YHR210C| NO SYMBOL GRF10(Pho2), PHO4
YPR183W DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YMR002W NO SYMBOL NDD1, REB1, SWI6
YLR333C RPS25B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, RAP1
|YDL078C| MDH3 glyoxylate cycle, malate metabolism, fatty acid beta-oxidation, NADH regeneration ->
aldehyde metabolism, carbohydrate metabolism, lipid metabolism, coenzymes and prosthetic group metabolism, organic acid metabolism, vitamin metabolism, energy pathways malic enzyme activity ->
malic enzyme activity peroxisomal matrix ->
cytoplasm MIG1
YPL106C SSE1 protein folding ->
protein metabolism co-chaperone activity ->
co-chaperone activity cytoplasm ->
cytoplasm HSF1, MSN4
YJR044C VPS55 late endosome to vacuole transport ->
cell organization and biogenesis, transport late endosome ->
cytoplasm ACE2, CAD1, FZF1, GAL4, GAT3, GCR2, HIR1, IME4, MBP1, NDD1, PDR1, RGM1, SMP1, SWI4, SWI5, YAP5, ZMS1
YOR270C VPH1 polyphosphate metabolism, vacuolar acidification ->
phosphorus metabolism, cell homeostasis, cell organization and biogenesis, transport hydrogen-transporting ATPase V0 domain, vacuole ->
cytoplasm ABF1
Main: protein metabolism (0.50) dolichyl-phosphate beta-D-mannosyltransferase activity (0.25) cytoplasm (1.00) SWI5 NDD1 (0.25)
Score: 0.27 0.00 1.00 0.071
P-value: 7.516E-01 (lipid metabolism) 2.849E+00 (enzyme activity) 1.578E+00 (cytoplasm) 3.654E-01 (SWI5)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n7(1) => SimExpr(YOR270C) OR SimExpr(other) : 5 2

EXPR: (0.201) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.002) m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n7 (P < 0.010)

ORF SYMBOL P F C TF
YMR109W MYO5 exocytosis, endocytosis, response to osmotic stress, cell wall organization and biogenesis, polar budding, salinity response ->
transport, external encapsulating structure organization and biogenesis, asexual reproduction, response to abiotic stimulus microfilament motor activity ->
microfilament motor activity actin cortical patch (sensu Saccharomyces) ->
cell cortex, cytoplasm
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
|YJL039C| NUP192 nuclear pore organization and biogenesis ->
cell organization and biogenesis structural molecule activity ->
structural molecule activity nuclear pore ->
nucleus, integral to membrane, endomembrane system
YKR091W SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm DIG1, RLM1, STE12
|YGL056C| SDS23 cytoplasm, nucleus ->
cytoplasm, nucleus HSF1
YPL078C ATP4 ATP synthesis coupled proton transport ->
transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane REB1, ZAP1
YOR270C VPH1 polyphosphate metabolism, vacuolar acidification ->
phosphorus metabolism, cell homeostasis, cell organization and biogenesis, transport hydrogen-transporting ATPase V0 domain, vacuole ->
cytoplasm ABF1
Main: transport (0.50) structural molecule activity (0.50) cytoplasm (0.86) ABF1 (0.20)
Score: 0.27 0.17 0.81 0.000
P-value: 1.245E+00 (transport) 3.788E-01 (structural molecule activity) 4.612E-01 (integral to membrane) 4.768E-01 (ZAP1)

m_pentose-phosphate_pathway_orfnum2SD_n21(1) AND m_glycolysis_and_gluconeogenesis_orfnum2SD_n14(1) => SimExpr(YLR251W) OR SimExpr(other) : 5 2

EXPR: (0.219) m_pentose-phosphate_pathway_orfnum2SD_n21 (P < 0.007) m_glycolysis_and_gluconeogenesis_orfnum2SD_n14 (P < 0.005)

MCM1(1) AND PDR(1) => SimExpr(YOR273C) OR SimExpr(other) : 8 3

EXPR: (0.234) MCM1 (P < 0.014) PDR (P < 0.013)

m_other_transport_facilitators_orfnum2SD_n10(1) AND MCM1(1) => SimExpr(YOR273C) OR SimExpr(other) : 7 2

EXPR: (0.213) m_other_transport_facilitators_orfnum2SD_n10 (P < 0.005) MCM1 (P < 0.002)

ORF SYMBOL P F C TF
|YOL011W| PLB3 phosphoinositide metabolism, phosphatidylserine catabolism ->
catabolism, lipid metabolism lysophospholipase activity ->
lysophospholipase activity extracellular space, plasma membrane ->
extracellular space, plasma membrane SWI4
YOR273C TPO4 polyamine transport ->
transport spermine transporter activity, spermidine transporter activity ->
spermine transporter activity, spermidine transporter activity plasma membrane, vacuolar membrane ->
plasma membrane, cytoplasm ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YGR086C PIL1 ASH1, SWI5
|YJL158C| CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transketolase activity cytoplasm ->
cytoplasm REB1
YKL104C GFA1 cell wall chitin biosynthesis ->
cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity ->
glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity REB1
YOR051C NO SYMBOL PHD1, SFL1
Main: cell organization and biogenesis (0.43) structural constituent of cell wall (0.14) cytoplasm (0.80) REB1 (0.33)
Score: 0.33 0.00 0.80 0.194
P-value: 1.618E-01 (carbohydrate metabolism) 1.715E+00 (transferase activity) 1.161E-01 (plasma membrane) 9.226E-02 (REB1)

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n8.scn(1) => SimExpr(YOR273C) OR SimExpr(other) : 6 2

EXPR: (0.212) m_regulation_of_amino-acid_metabolism_orfnum2SD_n15 (P < 0.008) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n8.scn (P < 0.003)

ORF SYMBOL P F C TF
|YMR215W| GAS3 cell wall (sensu Fungi) ->
cell wall FKH1, FKH2, MBP1, SWI6
YOR273C TPO4 polyamine transport ->
transport spermine transporter activity, spermidine transporter activity ->
spermine transporter activity, spermidine transporter activity plasma membrane, vacuolar membrane ->
membrane, cytoplasm ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YNL208W NO SYMBOL INO2
|YLR205C| HMX1 iron ion homeostasis ->
cell homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, membrane HAP4, MBP1
YNL302C RPS19B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, RAP1
YGR193C PDX1 acetyl-CoA biosynthesis from pyruvate ->
biosynthesis, coenzymes and prosthetic group metabolism, organic acid metabolism protein binding ->
protein binding mitochondrion, pyruvate dehydrogenase complex (sensu Eukarya) ->
cytoplasm, pyruvate dehydrogenase complex SWI4
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
Main: biosynthesis (0.33) structural constituent of cell wall (0.17) cytoplasm (0.57) SWI4 PHO4 MBP1 SKN7 (0.25)
Score: 0.07 0.00 0.43 0.107
P-value: 3.781E+00 (biosynthesis) 8.514E-01 (oxidoreductase activity) 1.087E-01 (cell wall (sensu Fungi)) 3.850E-01 (PHO4)

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_mitochondrial_biogenesis_orfnum2SD_n5(1) => SimExpr(YOR273C) OR SimExpr(other) : 8 3

EXPR: (0.228) m_regulation_of_amino-acid_metabolism_orfnum2SD_n15 (P < 0.011) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.002)

ORF SYMBOL P F C TF
|YOR085W| OST3 N-linked glycosylation, protein complex assembly, protein amino acid glycosylation ->
biosynthesis, protein metabolism, glycoprotein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity ->
transferase activity\, transferring glycosyl groups integral to membrane, oligosaccharyl transferase complex ->
integral to membrane, cytoplasm, endomembrane system
|YFR028C| CDC14 DNA dependent DNA replication, protein amino acid dephosphorylation, regulation of exit from mitosis ->
phosphorus metabolism, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein phosphatase activity ->
hydrolase activity\, acting on ester bonds nucleus, spindle pole body, nucleolus ->
cytoplasm, nucleus, microtubule organizing center
YOR273C TPO4 polyamine transport ->
transport spermine transporter activity, spermidine transporter activity ->
polyamine transporter activity plasma membrane, vacuolar membrane ->
plasma membrane, cytoplasm ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YGL191W COX13 aerobic respiration ->
energy pathways cytochrome c oxidase activity, enzyme regulator activity ->
heme-copper terminal oxidase activity, enzyme regulator activity, oxidoreductase activity\, acting on heme group of donors, primary active transporter activity, cation transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane DOT6, HAP4, REB1, RGT1
|YJR060W| CBF1 methionine biosynthesis, DNA replication and chromosome cycle ->
cell proliferation, amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism DNA binding, centromeric DNA binding ->
DNA binding nucleus ->
nucleus CBF1
YNL302C RPS19B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, RAP1
YOL065C INP54 exocytosis ->
transport inositol-1\,4\,5-trisphosphate 5-phosphatase activity ->
hydrolase activity\, acting on ester bonds endoplasmic reticulum ->
cytoplasm AZF1, SIP4
YOR133W EFT1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex
YPR162C ORC4 pre-replicative complex formation and maintenance, DNA replication initiation, chromatin silencing at HML and HMR (sensu Saccharomyces) ->
nuclear organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription, DNA metabolism DNA replication origin binding ->
DNA binding nuclear origin of replication recognition complex ->
chromosome, nucleoplasm, nucleus
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
YPL096W PNG1 misfolded or incompletely synthesized protein catabolism, protein deglycosylation ->
catabolism, protein metabolism peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds nucleus, cytosol ->
nucleus, cytoplasm CBF1, HIR1, USV1
Main: protein metabolism (0.45) DNA binding (0.18) cytoplasm (0.73) CBF1 HIR1 (0.29)
Score: 0.29 0.04 0.60 0.095
P-value: 3.834E-01 (glycoprotein metabolism) 5.765E-01 (phosphoric monoester hydrolase activity) 2.077E+00 (endoplasmic reticulum) 2.056E-01 (CBF1)

m_organization_of_cell_wall_orfnum2SD_n6(1) AND m_organization_of_cell_wall_orfnum2SD_n8(1) => SimExpr(YNL066W) OR SimExpr(other) : 7 3

EXPR: (0.232) m_organization_of_cell_wall_orfnum2SD_n8 (P < 0.013) m_organization_of_cell_wall_orfnum2SD_n6 (P < 0.013)

m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) AND m_g-proteins_orfnum2SD_n13(1) => SimExpr(YFL045C) OR SimExpr(other) : 5 1

EXPR: (0.195) m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5 (P < 0.007) m_g-proteins_orfnum2SD_n13 (P < 0.000)

ORF SYMBOL P F C TF
|YGL040C| HEM2 heme biosynthesis ->
pigment metabolism, coenzymes and prosthetic group biosynthesis, coenzymes and prosthetic group metabolism, biosynthesis, heterocycle metabolism porphobilinogen synthase activity ->
porphobilinogen synthase activity
YPR016C TIF6 ribosomal large subunit biogenesis, processing of 27S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleus, cytoplasm ->
nucleus, cytoplasm CIN5
YPL028W ERG10 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism acetyl-CoA C-acetyltransferase activity ->
acetyl-CoA C-acetyltransferase activity cytosol ->
cytoplasm MTH1
YGL105W ARC1 tRNA-nucleus export, amino acid activation ->
transport, biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism tRNA binding ->
tRNA binding cytoplasm, methionyl glutamyl tRNA synthetase complex ->
cytoplasm, methionyl glutamyl tRNA synthetase complex
YDL145C COP1 retrograde (Golgi to ER) transport, ER to Golgi transport ->
transport, vesicle-mediated transport COPI vesicle coat ->
cytoplasm ABF1
YFL045C SEC53 protein-ER targeting ->
cell organization and biogenesis, protein metabolism, transport phosphomannomutase activity ->
phosphomannomutase activity cytosol ->
cytoplasm
Main: biosynthesis (0.50) phosphomannomutase activity (0.25) cytoplasm (1.00) ABF1 (0.33)
Score: 0.53 0.00 1.00 0.000
P-value: 2.542E-01 (intracellular transport) 2.077E+00 (enzyme activity) 8.352E-01 (cytosol) 3.600E-01 (MTH1)

MCB(1) AND CSRE(1) => SimExpr(YML027W) OR SimExpr(other) : 5 2

EXPR: (0.190) CSRE (P < 0.000) MCB (P < 0.100)

ORF SYMBOL P F C TF
YHR110W ERP5 secretory pathway ->
secretory pathway integral to membrane ->
integral to membrane DOT6, RGT1
|YMR279C| NO SYMBOL IXR1, MIG1, MTH1, RFX1, SWI4, SWI6
YDR134C NO SYMBOL ASH1, NRG1, SOK2, SWI4
YDR309C GIC2 axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) ->
axial budding, small GTPase mediated signal transduction, organelle organization and biogenesis small GTPase regulatory/interacting protein activity ->
small GTPase regulatory/interacting protein activity actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site ->
cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6
|YJR006W| HYS2 leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair ->
mutagenesis, DNA repair, postreplication repair, DNA replication and chromosome cycle, mitotic cell cycle, DNA metabolism delta DNA polymerase activity ->
delta DNA polymerase activity delta DNA polymerase complex ->
cytoplasm, nucleus ABF1
YMR076C PDS5 mitotic sister chromatid cohesion, mitotic chromosome condensation ->
DNA replication and chromosome cycle, M phase, mitotic cell cycle structural molecule activity ->
structural molecule activity condensed nuclear chromosome ->
chromosome, nucleus FKH2, MBP1, SWI6
YML027W YOX1 negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
mitotic cell cycle, M phase, regulation of transcription, nuclear division, transcription\, DNA-dependent, regulation of cell cycle specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding nucleus ->
nucleus MBP1, SWI4, SWI6
Main: mitotic cell cycle (0.60) DNA binding (0.25) nucleus (0.60) SWI4 SWI6 (0.57)
Score: 0.30 0.00 0.40 0.429
P-value: 1.664E-01 (mitotic cell cycle) 2.000E+00 2.837E+00 (nucleus) 5.504E-04 (SWI6)

ALPHA1(1) AND MCB(1) => SimExpr(YML027W) OR SimExpr(other) : 22 10

m_MERE4(1) AND m_other_transcription_activities_orfnum2SD_n5(1) => SimExpr(YOR230W) OR SimExpr(other) : 7 2

EXPR: (0.191) m_other_transcription_activities_orfnum2SD_n5 (P < 0.002) m_MERE4 (P < 0.001)

ORF SYMBOL P F C TF
YOR155C ISN1
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YOR230W WTM1 regulation of meiosis ->
cell cycle transcription co-repressor activity ->
transcription co-repressor activity nucleus ->
nucleus CIN5, HIR2, INO2, INO4
YLR205C HMX1 iron ion homeostasis ->
cell ion homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy derivation by oxidation of organic compounds, electron transport, phosphate metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, membrane HAP4, MBP1
|YJL079C| PRY1 nuclear membrane, endoplasmic reticulum ->
nucleus, cytoplasm, membrane NDD1, PHD1, RAP1
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
trehalose phosphatase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
YPL154C PEP4 microautophagy, vacuolar protein catabolism, sporulation, cellular response to starvation ->
microautophagy, macromolecule catabolism, sporulation, response to extracellular stimulus, protein metabolism, response to stress saccharopepsin activity, endopeptidase activity ->
saccharopepsin activity, endopeptidase activity vacuole (sensu Fungi) ->
cytoplasm
|YML027W| YOX1 negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
regulation of transcription, M phase, transcription, cell cycle specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding nucleus ->
nucleus MBP1, SWI4, SWI6
Main: response to stress (0.29) DNA binding (0.14) cytoplasm (0.50) MBP1 (0.33)
Score: 0.19 0.00 0.39 0.067
P-value: 9.519E-01 (energy pathways) 1.862E-01 (oxidoreductase activity) 2.695E+00 (mitochondrion) 4.545E-01 (MBP1)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_purine_and_pyrimidine_transporters_orfnum2SD_n6(1) => SimExpr(YOR230W) : 5

EXPR: (0.174) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.000) m_purine_and_pyrimidine_transporters_orfnum2SD_n6 (P < 0.001)

PAC(1) AND ALPHA1'(1) AND m_rRSE10(1) => SimExpr(YNL132W) OR SimExpr(other) : 7 3

EXPR: (0.234) m_rRSE10 (P < 0.001) PAC (P < 0.095) ALPHA1' (P < 0.000)

SFF'(1) AND PAC(1) AND m_rRSE10(1) => SimExpr(YNL132W) OR SimExpr(other) : 9 3

EXPR: (0.223) SFF' (P < 0.000) m_rRSE10 (P < 0.000) PAC (P < 0.018)

ORF SYMBOL P F C TF
YDR101C ARX1 ribosomal large subunit biogenesis ->
ribosome biogenesis and assembly nucleoplasm, cytoplasm ->
nucleus, cytoplasm IXR1, RFX1
YML043C RRN11 transcription from Pol I promoter ->
transcription\, DNA-dependent RNA polymerase I transcription factor activity ->
RNA polymerase I transcription factor activity RNA polymerase I transcription factor complex ->
nucleus MAL13
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YKL078W DHR2 ribosome biogenesis ->
ribosome biogenesis and assembly RNA helicase activity ->
RNA binding nucleolus ->
nucleus ABF1
YGR145W ENP2
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus MATa1, RCS1, RTG3, SWI5
|YOR381W| FRE3 iron-siderochrome transport, iron ion homeostasis ->
iron-siderochrome transport, cation homeostasis ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions plasma membrane, integral to membrane ->
plasma membrane, integral to membrane CIN5, PDR1, YAP6
|YLR249W| YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YNL132W KRE33
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent RNA binding ->
RNA binding nucleolus ->
nucleus
YOL141W PPM2 C-terminal protein carboxyl methyltransferase activity ->
transferase activity\, transferring one-carbon groups ARG81, SRD1
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
Main: ribosome biogenesis and assembly (0.56) RNA binding (0.44) nucleus (0.67) SWI5 (0.22)
Score: 0.39 0.17 0.50 0.028
P-value: 1.643E-03 (ribosome biogenesis) 5.296E-03 (RNA helicase activity) 6.012E-04 (nucleolus) 5.111E-01 (SWI5)

PAC(1) AND ALPHA1'(1) AND mRRPE(1) AND m_rRSE10(1) => SimExpr(YNL132W) OR SimExpr(other) : 5 2

EXPR: (0.212) mRRPE (P < 0.004) m_rRSE10 (P < 0.001) PAC (P < 0.036) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
glycoprotein biosynthesis, glycerophospholipid biosynthesis, lipoprotein biosynthesis, glycerophospholipid metabolism, protein modification transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network SWI5
YPR010C RPA135 transcription from Pol I promoter ->
transcription from Pol I promoter DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleolus ROX1, SIG1
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosome assembly, ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus MATa1, RCS1, RTG3, SWI5
|YOR381W| FRE3 iron-siderochrome transport, iron ion homeostasis ->
iron-siderochrome transport, di-\, tri-valent inorganic cation homeostasis, metal ion homeostasis ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions plasma membrane, integral to membrane ->
plasma membrane, integral to membrane CIN5, PDR1, YAP6
YNL132W KRE33
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis, snRNA processing, RNA processing, transcription from Pol I promoter RNA binding ->
RNA binding nucleolus ->
nucleolus
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus HIR2, USV1
Main: transcription from Pol I promoter (0.67) RNA binding (0.50) nucleolus (0.67) SWI5 (0.40)
Score: 0.40 0.20 0.40 0.100
P-value: 9.461E-04 (transcription from Pol I promoter) 1.420E-02 (ATP dependent RNA helicase activity) 6.066E-04 (nucleolus) 1.133E-01 (SWI5)

SFF'(1) AND m_RRSE3(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YNL132W) OR SimExpr(other) : 17 8

EXPR: (0.238) SFF' (P < 0.000) mRRPE (P < 0.000) m_RRSE3 (P < 0.000) ALPHA1' (P < 0.000)

m_RRSE3(1) AND PAC(1) AND ALPHA1'(1) => SimExpr(YNL132W) OR SimExpr(other) : 25 12

EXPR: (0.235) m_RRSE3 (P < 0.000) PAC (P < 0.011) ALPHA1' (P < 0.000)

m_RRSE3(1) AND PAC(1) AND m_rRSE10(1) => SimExpr(YNL132W) OR SimExpr(other) : 8 2

EXPR: (0.213) m_RRSE3 (P < 0.000) m_rRSE10 (P < 0.000) PAC (P < 0.015)

m_RRSE3(1) AND PAC(1) AND mRRPE(1) => SimExpr(YNL132W) OR SimExpr(other) : 31 8

EXPR: (0.216) mRRPE (P < 0.000) m_RRSE3 (P < 0.000) PAC (P < 0.000)

PAC(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n18(1) => SimExpr(YNL132W) OR SimExpr(other) : 7 3

EXPR: (0.212) m_other_nucleotide-metabolism_activities_orfnum2SD_n18 (P < 0.000) PAC (P < 0.011)

m_RRSE3(1) AND PAC(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YNL132W) OR SimExpr(other) : 7 3

EXPR: (0.208) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) m_RRSE3 (P < 0.000) PAC (P < 0.006)

ORF SYMBOL P F C TF
|YPR149W| NCE102 protein secretion ->
protein secretion integral to membrane, endoplasmic reticulum, cytoplasm ->
integral to membrane, cytoplasm CIN5, FKH2, GRF10(Pho2), HSF1, NDD1, PUT3, RAP1, SKN7, SWI4, YAP6
YHR052W CIC1 protein catabolism ->
macromolecule catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
YNL110C NOP15 ribosomal large subunit biogenesis ->
cytoplasm organization and biogenesis nucleus, nucleolus ->
nucleus
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
|YLR197W| SIK1 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription\, DNA-dependent small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex DAL81, HAL9
YNL132W KRE33
|YMR014W| BUD22 bud site selection ->
cytokinesis, cytoplasm organization and biogenesis nucleus ->
nucleus CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YNL075W IMP4 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription\, DNA-dependent rRNA primary transcript binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex USV1
YJL033W HCA4 35S primary transcript processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YNL292W PUS4 tRNA modification ->
RNA metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
Main: cytoplasm organization and biogenesis (0.62) RNA binding (0.50) nucleus (0.88) HIR2 RCS1 USV1 YAP6 NDD1 HAL9 (0.25)
Score: 0.46 0.17 0.82 0.179
P-value: 2.266E-03 (RNA modification) 1.130E+00 (RNA binding) 2.494E-04 (nucleolus) 1.230E-01 (USV1)

m_g-proteins_orfnum2SD_n12(1) AND LYS14(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YMR205C) OR SimExpr(other) : 5 2

EXPR: (0.224) LYS14 (P < 0.008) m_g-proteins_orfnum2SD_n12 (P < 0.002) m_cell_death_orfnum2SD_n16 (P < 0.022)

ORF SYMBOL P F C TF
YJR145C RPS4A protein biosynthesis ->
macromolecule biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm ->
cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YAL060W BDH1 butanediol fermentation ->
energy derivation by oxidation of organic compounds (R\,R)-butanediol dehydrogenase activity ->
(R\,R)-butanediol dehydrogenase activity cytoplasm ->
cytoplasm
YMR205C PFK2 glycolysis ->
alcohol catabolism, carbohydrate metabolism, monosaccharide metabolism, carbohydrate catabolism, energy derivation by oxidation of organic compounds 6-phosphofructokinase activity ->
6-phosphofructokinase activity 6-phosphofructokinase complex, cytoplasm ->
6-phosphofructokinase complex, cytoplasm RAP1
YGR125W NO SYMBOL ACE2, MBP1, PUT3, SWI6, YFL044C
|YFR015C| GSY1 glycogen metabolism ->
polysaccharide metabolism, energy derivation by oxidation of organic compounds glycogen (starch) synthase activity ->
glycogen (starch) synthase activity INO4
YML017W PSP2
|YDR528W| HLR1 cell wall organization and biogenesis ->
external encapsulating structure organization and biogenesis MBP1, MCM1, SWI6
Main: energy derivation by oxidation of organic compounds (0.60) 6-phosphofructokinase activity (0.25) cytoplasm (1.00) ACE2 MBP1 SWI6 RAP1 INO4 (0.40)
Score: 0.30 0.00 1.00 0.400
P-value: 2.391E-02 (energy pathways) 1.225E+00 (transferase activity) 1.086E+00 (cytosol) 4.702E-02 (ACE2)

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YOR032C) OR SimExpr(other) : 5 1

EXPR: (0.163) m_regulation_of_amino-acid_metabolism_orfnum2SD_n15 (P < 0.000) m_peroxisomal_transport_orfnum2SD_n22 (P < 0.001)

ORF SYMBOL P F C TF
YOR032C HMS1 pseudohyphal growth ->
cell organization and biogenesis transcription factor activity ->
transcription factor activity CUP9, HAL9, INO4, NRG1, RAP1, SFP1, YAP6
YNL208W NO SYMBOL INO2
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YPL203W TPK2 protein amino acid phosphorylation, pseudohyphal growth, RAS protein signal transduction ->
phosphorus metabolism, cell organization and biogenesis, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex
|YDL092W| SRP14 protein-ER targeting ->
cell organization and biogenesis, protein metabolism, transport signal sequence binding ->
signal sequence binding signal recognition particle ->
cytoplasm ABF1, PHD1, RPH1
YOR299W BUD7 bud site selection ->
cell proliferation, cell organization and biogenesis HSF1, MTH1
Main: cell organization and biogenesis (0.80) ubiquinol-cytochrome c reductase activity (0.25) cytoplasm (1.00) ABF1 (0.20)
Score: 0.70 0.00 1.00 0.000
P-value: 7.940E-02 (pseudohyphal growth) 2.408E+00 (binding) 3.918E+00 (cytoplasm) 5.340E-01 (RPH1)

m_tricarboxylic-acid_pathway_orfnum2SD_n9(1) AND mRRPE(1) => SimExpr(YPR080W) OR SimExpr(other) : 5 1

EXPR: (0.192) mRRPE (P < 0.003) m_tricarboxylic-acid_pathway_orfnum2SD_n9 (P < 0.000)

ORF SYMBOL P F C TF
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YMR296C LCB1 sphingolipid biosynthesis ->
biosynthesis, lipid metabolism serine C-palmitoyltransferase activity ->
serine C-palmitoyltransferase activity membrane fraction, microsome, serine C-palmitoyltransferase complex ->
membrane fraction, endoplasmic reticulum, endomembrane system ABF1
|YGL099W| LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction GTPase activity ->
GTPase activity cytoplasm ->
cytoplasm PHO4
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
YIL133C RPL16A protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, PUT3, RAP1, RGM1, SFP1, SMP1, YAP5
YMR308C PSE1 mRNA-nucleus export ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein carrier activity ->
protein carrier activity nucleus, cytoplasm ->
nucleus, cytoplasm SWI4
Main: biosynthesis (0.67) RNA binding (0.17) cytoplasm (0.83) FHL1 PDR1 RAP1 YAP5 (0.33)
Score: 0.60 0.00 0.67 0.067
P-value: 1.239E-01 (nucleocytoplasmic transport) 3.918E-01 (binding) 2.840E-01 (cytoplasm) 5.234E-02 (YAP5)

RAP1(1) AND m_other_mrna-transcription_activities_orfnum2SD_n20(1) => SimExpr(YPR080W) OR SimExpr(other) : 8 2

m_osmosensing_orfnum2SD_n6(1) AND RAP1(1) => SimExpr(YPR080W) OR SimExpr(other) : 6 2

RAP1(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YGR085C) OR SimExpr(other) : 7 3

EXPR: (0.178) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) RAP1 (P < 0.100)

RAP1(1) AND m_g-proteins_orfnum2SD_n13(1) => SimExpr(YGR085C) OR SimExpr(other) : 5 1

RAP1(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) => SimExpr(YGR085C) OR SimExpr(other) : 5 2

EXPR: (0.161) m_allantoin_and_allantoate_transporters_orfnum2SD_n13 (P < 0.000) RAP1 (P < 0.073)

m_osmosensing_orfnum2SD_n6(1) AND RAP1(1) => SimExpr(YGR085C) OR SimExpr(other) : 6 2

RAP1(1) AND MCM1'(1) => SimExpr(YGR085C) OR SimExpr(other) : 18 2

MCM1'(1) AND m_RRSE3(1) AND m_other_signal-transduction_activities_orfnum2SD_n13(1) => SimExpr(YGR085C) OR SimExpr(other) : 5 2

EXPR: (0.227) m_RRSE3 (P < 0.006) m_other_signal-transduction_activities_orfnum2SD_n13 (P < 0.008) MCM1' (P < 0.004)

ORF SYMBOL P F C TF
YGL026C TRP5 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism tryptophan synthase activity ->
tryptophan synthase activity cytoplasm ->
cytoplasm
|YMR302C| PRP12 mitochondrial genome maintenance, rRNA processing ->
cell organization and biogenesis, RNA metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism exonuclease activity ->
exonuclease activity mitochondrial inner membrane ->
cytoplasm, inner membrane
YKL116C PRR1 MAPKKK cascade ->
signal transduction receptor signaling protein serine/threonine kinase activity ->
receptor signaling protein serine/threonine kinase activity
YOR230W WTM1 regulation of meiosis ->
cell proliferation transcription co-repressor activity ->
transcription co-repressor activity nucleus ->
nucleus CIN5, HIR2, INO2, INO4
YGR085C RPL11B protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MIG1
YML086C ALO1 response to oxidative stress ->
oxygen and reactive oxygen species metabolism, response to biotic stimulus D-arabinono-1\,4-lactone oxidase activity ->
D-arabinono-1\,4-lactone oxidase activity mitochondrion ->
cytoplasm SIP4
|YHR211W| FLO5 flocculation ->
cell adhesion cell adhesion molecule activity ->
cell adhesion molecule activity cell wall (sensu Fungi) ->
cell wall GRF10(Pho2), PHO4
Main: cell organization and biogenesis (0.29) D-arabinono-1\,4-lactone oxidase activity (0.14) cytoplasm (0.67) PHO4 (0.25)
Score: 0.10 0.00 0.40 0.000
P-value: 4.648E-01 (ribosome biogenesis and assembly) 2.171E+00 (enzyme activity) 1.397E+00 (mitochondrion) 6.308E-01 (MIG1)

m_RPE8(1) AND m_other_intracellular-transport_activities_orfnum2SD_n6(1) => SimExpr(YAR020C) OR SimExpr(other) : 5 2

EXPR: (0.200) m_other_intracellular-transport_activities_orfnum2SD_n6 (P < 0.000) m_RPE8 (P < 0.024)

ORF SYMBOL P F C TF
|YPR075C| OPY2 cell cycle arrest in response to pheromone ->
cell proliferation, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus cytoplasm ->
cytoplasm MBP1, SWI6
YAR020C PAU7
|YPR119W| CLB2 regulation of CDK activity, G2/M transition of mitotic cell cycle ->
cell proliferation cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity nucleus, cytoplasm ->
nucleus, cytoplasm FKH1, FKH2, MBP1, MCM1, NDD1, REB1, SOK2, SWI4, SWI6
YNL284C MRPL10 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex REB1, RTG1
YJL158C CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YKL122C SRP21 protein-ER targeting ->
cell organization and biogenesis, protein metabolism, transport signal sequence binding ->
signal sequence binding nucleus, signal recognition particle ->
nucleus, cytoplasm REB1
YDR086C SSS1 cotranslational membrane targeting ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity translocon ->
cytoplasm HIR1, IXR1, MIG1, RFX1, SIP4
Main: cell organization and biogenesis (0.50) structural constituent of cell wall (0.20) cytoplasm (1.00) REB1 (0.67)
Score: 0.40 0.00 1.00 0.533
P-value: 1.617E-02 (protein-ER targeting) 4.947E-01 (structural molecule activity) 7.443E-02 (endoplasmic reticulum) 1.155E-03 (REB1)

m_RPE8(1) AND CSRE(1) => SimExpr(YAR020C) OR SimExpr(other) : 11 4

m_homeostasis_of_metal_ions_orfnum2SD_n20(1) AND m_RPE8(1) => SimExpr(YAR020C) OR SimExpr(other) : 5 1

EXPR: (0.179) m_homeostasis_of_metal_ions_orfnum2SD_n20 (P < 0.003) m_RPE8 (P < 0.007)

m_ion_transporters_orfnum2SD_n3(1) AND m_amino-acid_transporters_orfnum2SD_n11(1) => SimExpr(YJL171C) OR SimExpr(other) : 6 2

m_PNDE6(1) AND m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_organization_of_chromosome_structure_orfnum2SD_n17(1) => SimExpr(YML075C) OR SimExpr(other) : 5 1

EXPR: (0.214) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.002) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.017) m_PNDE6 (P < 0.007)

ORF SYMBOL P F C TF
YKL218C NO SYMBOL
YML075C HMG1 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism hydroxymethylglutaryl-CoA reductase (NADPH) activity ->
hydroxymethylglutaryl-CoA reductase (NADPH) activity mitochondrial matrix, nuclear membrane, endoplasmic reticulum membrane ->
nucleus, cytoplasm, nuclear envelope-endoplasmic reticulum network, endomembrane system GRF10(Pho2), INO2, INO4
YGR184C UBR1 protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity proteasome complex (sensu Eukarya) ->
cytoplasm, nucleus HMS1, REB1, RIM101
YJR123W RPS5 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GRF10(Pho2), HSF1, MSN4, YAP1
|YLR272C| YCS4 mitotic chromosome condensation ->
cell proliferation, cell cycle nuclear condensin complex ->
chromosome, nucleus
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
Main: biosynthesis (0.60) translation elongation factor activity (0.25) cytoplasm (0.80) FHL1 GRF10(Pho2) (0.50)
Score: 0.50 0.00 0.80 0.333
P-value: 9.414E-01 (biosynthesis) 2.725E+00 (enzyme activity) 6.517E-01 (endoplasmic reticulum) 7.089E-02 (GRF10(Pho2))

ALPHA1(1) AND m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_abc_transporters_orfnum2SD_n10(1) => SimExpr(YML075C) OR SimExpr(other) : 5 2

EXPR: (0.234) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.014) ALPHA1 (P < 0.018) m_abc_transporters_orfnum2SD_n10 (P < 0.026)

ORF SYMBOL P F C TF
YML075C HMG1 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism hydroxymethylglutaryl-CoA reductase (NADPH) activity ->
hydroxymethylglutaryl-CoA reductase (NADPH) activity mitochondrial matrix, nuclear membrane, endoplasmic reticulum membrane ->
nucleus, cytoplasm, nuclear envelope-endoplasmic reticulum network, endomembrane system GRF10(Pho2), INO2, INO4
YGR085C RPL11B protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MIG1
|YMR229C| RRP5 rRNA processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding, snoRNA binding ->
RNA binding, snoRNA binding nucleolus, nucleolus organizer complex ->
nucleus FHL1, RAP1
YDR377W ATP17 ATP synthesis coupled proton transport ->
transport hydrogen-transporting ATP synthase activity ->
hydrogen ion transporter activity proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane ARO80, HAP2, HAP3, HAP4, RPH1
YLR395C COX8 aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors\, oxygen as acceptor, primary active transporter activity, hydrogen ion transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
|YGL096W| TOS8 transcription factor activity ->
transcription factor activity IXR1, SOK2, SWI4
YPR193C HPA2 histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism histone acetyltransferase activity ->
acyltransferase activity cytoplasm ->
cytoplasm
Main: cell organization and biogenesis (0.50) hydrogen ion transporter activity (0.29) cytoplasm (0.83) FHL1 HAP4 (0.33)
Score: 0.27 0.05 0.73 0.133
P-value: 5.070E-01 (ribosome biogenesis and assembly) 2.381E-02 (hydrogen ion transporter activity) 3.220E-01 (mitochondrial inner membrane) 5.486E-02 (HAP4)

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_pentose-phosphate_pathway_orfnum2SD_n19(1) => SimExpr(YML075C) : 5

m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) AND m_anion_transporters_orfnum2SD_n4(1) => SimExpr(YKL152C) OR SimExpr(other) : 6 2

EXPR: (0.203) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.000) m_anion_transporters_orfnum2SD_n4 (P < 0.004)

ORF SYMBOL P F C TF
YOL123W HRP1 mRNA cleavage, mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cleavage/polyadenylation specificity factor activity ->
cleavage/polyadenylation specificity factor activity mRNA cleavage factor complex, nucleus ->
nucleus
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YPL143W RPL33A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MET4, NDD1, PDR1, RAP1, RME1
YKL152C GPM1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphoglycerate mutase activity ->
phosphoglycerate mutase activity cytosol ->
cytoplasm GCR1, GCR2, HSF1, RAP1
|YJL066C| MPM1 mitochondrion, membrane fraction ->
cytoplasm, membrane fraction
YDL128W VCX1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cytoplasm, vacuole MAC1, STE12
|YJL206C| NO SYMBOL SIG1, SKO1
Main: biosynthesis (0.50) aconitate hydratase activity (0.17) cytoplasm (0.86) RAP1 (0.33)
Score: 0.33 0.00 0.71 0.067
P-value: 8.316E-03 (tricarboxylic acid cycle) 2.641E+00 (enzyme activity) 2.939E-01 (mitochondrial matrix) 1.000E+00

RAP1(1) AND MCM1'(1) => SimExpr(YKL152C) OR SimExpr(other) : 18 2

RAP1(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn(1) => SimExpr(YKL152C) OR SimExpr(other) : 6 1

m_osmosensing_orfnum2SD_n6(1) AND RAP1(1) => SimExpr(YKL152C) OR SimExpr(other) : 6 2

m_glycolysis_and_gluconeogenesis_orfnum2SD_n4(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) => SimExpr(YKL152C) OR SimExpr(other) : 5 1

m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) => SimExpr(YKL152C) OR SimExpr(other) : 5 2

EXPR: (0.199) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.006) m_allantoin_and_allantoate_transporters_orfnum2SD_n6 (P < 0.004)

ORF SYMBOL P F C TF
|YMR281W| GPI12 GPI anchor biosynthesis ->
biosynthesis, membrane lipid metabolism, protein metabolism, lipid metabolism N-acetylglucosaminylphosphatidylinositol deacetylase activity ->
N-acetylglucosaminylphosphatidylinositol deacetylase activity endoplasmic reticulum membrane ->
cytoplasm, endomembrane system ABF1, REB1
YGL189C RPS26A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YKL152C GPM1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphoglycerate mutase activity ->
phosphoglycerate mutase activity cytosol ->
cytoplasm GCR1, GCR2, HSF1, RAP1
|YJR010W| MET3 sulfate assimilation, methionine metabolism ->
sulfur metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism sulfate adenylyltransferase (ATP) activity ->
sulfate adenylyltransferase (ATP) activity CBF1, DAL82, GRF10(Pho2), MET4, SIP4
YLR354C TAL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transaldolase activity ->
transaldolase activity cytoplasm ->
cytoplasm MBP1
YJL158C CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
Main: biosynthesis (0.43) structural constituent of cell wall (0.14) cytoplasm (1.00) REB1 (0.43)
Score: 0.33 0.00 1.00 0.190
P-value: 5.729E-02 (hexose catabolism) 8.244E-01 (structural molecule activity) 1.170E-01 (endoplasmic reticulum) 4.234E-02 (REB1)

RAP1(1) AND m_LFTE17(1) => SimExpr(YKL152C) : 7

RAP1(1) AND m_glycolysis_and_gluconeogenesis_orfnum2SD_n4(1) => SimExpr(YKL152C) : 5

EXPR: (0.129) RAP1 (P < 0.060) m_glycolysis_and_gluconeogenesis_orfnum2SD_n4 (P < 0.000)

ECB(1) AND m_cytokinesis_orfnum2SD_n11(1) => SimExpr(YGR279C) OR SimExpr(other) : 5 2

EXPR: (0.217) ECB (P < 0.008) m_cytokinesis_orfnum2SD_n11 (P < 0.011)

ORF SYMBOL P F C TF
|YPL255W| BBP1 microtubule nucleation ->
organelle organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton spindle pole body ->
spindle pole body STB1, SWI4
YGR161C RTS3 CIN5, GAT1
|YHR046C| INM1 myo-inositol metabolism ->
hexose metabolism myo-inositol-1(or 4)-monophosphatase activity ->
myo-inositol-1(or 4)-monophosphatase activity
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to DNA damage, organelle organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
protein biosynthesis, hexose metabolism, protein modification, nucleotide-sugar metabolism, glycoprotein metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
YMR014W BUD22 bud site selection ->
cytokinesis\, site selection, organelle organization and biogenesis nucleus ->
nucleus CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YGR279C SCW4 conjugation with cellular fusion ->
conjugation with cellular fusion glucosidase activity ->
glucosidase activity cell wall (sensu Fungi) ->
cell wall (sensu Fungi) ASH1, IXR1, PHD1, SWI4
Main: organelle organization and biogenesis (0.50) enzyme inhibitor activity (0.20) spindle pole body (0.33) SWI4 NDD1 (0.40)
Score: 0.27 0.00 0.00 0.200
P-value: 1.924E-01 (hexose metabolism) 1.611E+00 (hydrolase activity) 4.000E+00 (intracellular) 2.893E-01 (NDD1)

m_pentose-phosphate_pathway_orfnum2SD_n5(1) AND m_cytokinesis_orfnum2SD_n11(1) => SimExpr(YGR279C) OR SimExpr(other) : 5 1

EXPR: (0.230) m_pentose-phosphate_pathway_orfnum2SD_n5 (P < 0.004) m_cytokinesis_orfnum2SD_n11 (P < 0.018)

ORF SYMBOL P F C TF
|YOR378W| NO SYMBOL MTH1, RFX1, SWI4
YGR161C RTS3 CIN5, GAT1
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
YKL117W SBA1 protein folding ->
protein metabolism co-chaperone activity ->
co-chaperone activity nucleus, cytoplasm ->
nucleus, cytoplasm
YKR059W TIF1 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FKH1, FKH2
YGR279C SCW4 conjugation with cellular fusion ->
conjugation, sexual reproduction glucosidase activity ->
glucosidase activity cell wall (sensu Fungi) ->
cell wall ASH1, IXR1, PHD1, SWI4
Main: protein metabolism (0.75) translation initiation factor activity (0.25) cytoplasm (0.67) SWI4 (0.50)
Score: 0.50 0.00 0.33 0.167
P-value: 1.182E+00 (protein biosynthesis) 2.725E+00 (enzyme activity) 4.731E+00 (cytoplasm) 2.694E-01 (SWI4)

m_other_energy_generation_activities_orfnum2SD_n22(1) AND m_cytokinesis_orfnum2SD_n10(1) => SimExpr(YLR449W) OR SimExpr(other) : 6 2

EXPR: (0.229) m_cytokinesis_orfnum2SD_n10 (P < 0.010) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.004)

ORF SYMBOL P F C TF
YLR425W TUS1 signal transduction, cell wall organization and biogenesis ->
signal transduction, cell organization and biogenesis Rho guanyl-nucleotide exchange factor activity ->
Rho guanyl-nucleotide exchange factor activity UGA3
YLR449W FPR4 peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity nucleus ->
nucleus
YFR044C NO SYMBOL FKH1, PHO4, RIM101, UGA3, USV1
|YFL003C| MSH4 meiotic recombination ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA binding ->
DNA binding nuclear chromosome ->
chromosome, nucleus
|YJL082W| IML2
YMR043W MCM1 DNA replication initiation, regulation of transcription from Pol II promoter ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA replication origin binding, RNA polymerase II transcription factor activity, DNA binding ->
DNA replication origin binding, RNA polymerase II transcription factor activity, DNA binding nuclear chromatin, nucleus ->
nucleus, chromosome GAT1, MTH1
YDL140C RPO21 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase II\, core complex ->
nucleus REB1
YGL030W RPL30 protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation ->
cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, SFP1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.80) DNA binding (0.33) nucleus (0.80) UGA3 (0.40)
Score: 0.70 0.07 0.60 0.100
P-value: 7.827E-01 (transcription\, DNA-dependent) 6.105E-01 (DNA binding) 2.221E-01 (chromosome) 5.146E-02 (UGA3)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_other_energy_generation_activities_orfnum2SD_n22(1) AND m_cytokinesis_orfnum2SD_n10(1) => SimExpr(YLR449W) : 5

EXPR: (0.155) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) m_cytokinesis_orfnum2SD_n10 (P < 0.002) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.000)

ORF SYMBOL P F C TF
YLR449W FPR4 peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity nucleus ->
nucleus
YFR044C NO SYMBOL FKH1, PHO4, RIM101, UGA3, USV1
YMR043W MCM1 DNA replication initiation, regulation of transcription from Pol II promoter ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA replication origin binding, RNA polymerase II transcription factor activity, DNA binding ->
DNA replication origin binding, RNA polymerase II transcription factor activity, DNA binding nuclear chromatin, nucleus ->
nucleus, chromosome GAT1, MTH1
YDL140C RPO21 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase II\, core complex ->
nucleus REB1
YGL030W RPL30 protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation ->
cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, SFP1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00) DNA replication origin binding (0.25) nucleus (0.75) MTH1 (0.25)
Score: 1.00 0.00 0.50 0.000
P-value: 1.301E-01 (transcription\, DNA-dependent) 2.509E+00 (enzyme activity) 1.191E+00 (nucleus) 4.073E-01 (RIM101)

m_amino-acid_transport_orfnum2SD_n3(1) AND ALPHA1'(1) AND m_MERE11(1) => SimExpr(YFR015C) OR SimExpr(other) : 5 1

EXPR: (0.171) m_MERE11 (P < 0.000) ALPHA1' (P < 0.000) m_amino-acid_transport_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
YAL039C CYC3 cytochrome c-heme linkage ->
protein complex assembly, protein modification holocytochrome c synthase activity ->
holocytochrome c synthase activity mitochondrial intermembrane space ->
cytoplasm
|YOR136W| IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YFR015C GSY1 glycogen metabolism ->
polysaccharide metabolism, energy derivation by oxidation of organic compounds glycogen (starch) synthase activity ->
glycogen (starch) synthase activity INO4
YPL111W CAR1 arginine catabolism to ornithine ->
amine catabolism, amine metabolism, urea cycle intermediate metabolism, amino acid and derivative metabolism, carboxylic acid metabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YKL162C NO SYMBOL DOT6, RTG1
YOR062C NO SYMBOL GRF10(Pho2)
Main: amino acid and derivative metabolism (0.50) glycogen (starch) synthase activity (0.25) cytoplasm (1.00) RTG1 (0.20)
Score: 0.33 0.00 1.00 0.000
P-value: 2.684E-02 (glutamine family amino acid metabolism) 1.142E+00 (enzyme activity) 1.088E+00 (mitochondrion) 5.507E-01 (MET4)

m_MERE4(1) AND m_MERE11(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YFR015C) OR SimExpr(other) : 5 2

EXPR: (0.209) m_MERE11 (P < 0.005) m_cell_death_orfnum2SD_n16 (P < 0.000) m_MERE4 (P < 0.000)

ORF SYMBOL P F C TF
|YOL051W| GAL11 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase II transcription mediator activity ->
RNA polymerase II transcription mediator activity mediator complex ->
nucleus
|YNL241C| ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YMR139W RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MAL33, YJL206C
YLR258W GSY2 glycogen metabolism ->
carbohydrate metabolism, energy pathways glycogen (starch) synthase activity ->
glycogen (starch) synthase activity cytoplasm ->
cytoplasm
YFR015C GSY1 glycogen metabolism ->
carbohydrate metabolism, energy pathways glycogen (starch) synthase activity ->
glycogen (starch) synthase activity INO4
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
trehalose phosphatase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
Main: carbohydrate metabolism (0.57) glycogen (starch) synthase activity (0.29) cytoplasm (0.60) ACE2 (0.25)
Score: 0.48 0.05 0.30 0.000
P-value: 3.507E-03 (carbohydrate metabolism) 2.208E-04 (glycogen (starch) synthase activity) 4.385E+00 (cytoplasm) 5.694E-01 (ADR1)

m_LFTE17(1) AND m_other_cation_transporters_orfnum2SD_n3(1) => SimExpr(YFR015C) OR SimExpr(other) : 6 2

EXPR: (0.228) m_other_cation_transporters_orfnum2SD_n3 (P < 0.017) m_LFTE17 (P < 0.001)

ORF SYMBOL P F C TF
YHL021C NO SYMBOL GAT1, MAL13, MAL33, MTH1
YGL006W PMC1 calcium ion transport, calcium ion homeostasis ->
cation homeostasis, cation transport, metal ion homeostasis calcium-transporting ATPase activity ->
calcium-transporting ATPase activity vacuolar membrane (sensu Fungi) ->
vacuolar membrane (sensu Fungi) SKN7
YDR421W ARO80 positive regulation of transcription from Pol II promoter ->
regulation of transcription, transcription from Pol II promoter, transcription\, DNA-dependent specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ARO80, GAT1, YFL044C
|YML111W| BUL2 protein polyubiquitination, protein monoubiquitination ->
protein catabolism, protein modification PDR1, SMP1, SWI5, YAP5
|YJL165C| HAL5 cation homeostasis ->
cation homeostasis protein kinase activity ->
protein kinase activity
YFR015C GSY1 glycogen metabolism ->
glucan metabolism, energy reserve metabolism glycogen (starch) synthase activity ->
glycogen (starch) synthase activity INO4
YGR035C NO SYMBOL CIN5, MET4, SMP1, YAP6
YIL045W PIG2 protein phosphatase regulator activity ->
protein phosphatase regulator activity CIN5
Main: cation homeostasis (0.40) protein phosphatase regulator activity (0.20) nucleus (0.50) SMP1 GAT1 CIN5 (0.29)
Score: 0.10 0.00 0.00 0.143
P-value: 8.201E-02 (cation homeostasis) 1.475E+00 (transferase activity) 4.000E+00 (intracellular) 2.057E-02 (GAT1)

m_g-proteins_orfnum2SD_n11(1) AND m_peroxisomal_transport_orfnum2SD_n19(1) => SimExpr(YNR035C) OR SimExpr(other) : 7 1

m_osmosensing_orfnum2SD_n6(1) AND ABF1(1) AND m_g-proteins_orfnum2SD_n11(1) => SimExpr(YNR035C) OR SimExpr(other) : 5 1

EXPR: (0.170) m_g-proteins_orfnum2SD_n11 (P < 0.000) ABF1 (P < 0.000) m_osmosensing_orfnum2SD_n6 (P < 0.000)

ORF SYMBOL P F C TF
YNR035C ARC35 cell growth and/or maintenance ->
cell growth and/or maintenance structural molecule activity ->
structural molecule activity Arp2/3 protein complex ->
cytoplasm ABF1
|YKL119C| VPH2 protein complex assembly, vacuolar acidification ->
protein metabolism, cell growth and/or maintenance endoplasmic reticulum membrane ->
cytoplasm, endomembrane system
YMR297W PRC1 vacuolar protein catabolism ->
catabolism, protein metabolism carboxypeptidase C activity ->
carboxypeptidase C activity cytoplasm, endoplasmic reticulum ->
cytoplasm ABF1
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity CRZ1
YOR270C VPH1 polyphosphate metabolism, vacuolar acidification ->
phosphorus metabolism, cell growth and/or maintenance hydrogen-transporting ATPase V0 domain, vacuole ->
cytoplasm ABF1
YOR317W FAA1 N-terminal protein myristoylation, lipid metabolism, lipid transport ->
biosynthesis, lipid metabolism, cell growth and/or maintenance, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
long-chain-fatty-acid-CoA-ligase activity lipid particle ->
cytoplasm ASH1, CIN5, HSF1, INO4, RAP1
Main: cell growth and/or maintenance (0.67) long-chain-fatty-acid-CoA-ligase activity (0.25) cytoplasm (1.00) ABF1 (0.60)
Score: 0.60 0.00 1.00 0.300
P-value: 2.844E-03 (vacuolar acidification) 2.077E+00 (enzyme activity) 4.562E-01 (endoplasmic reticulum) 3.897E-02 (ABF1)

m_g-proteins_orfnum2SD_n11(1) AND m_peroxisomal_transport_orfnum2SD_n19(1) AND ALPHA1'(1) => SimExpr(YNR035C) : 7

EXPR: (0.167) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_peroxisomal_transport_orfnum2SD_n19 (P < 0.000) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
YAL060W BDH1 butanediol fermentation ->
energy pathways (R\,R)-butanediol dehydrogenase activity ->
(R\,R)-butanediol dehydrogenase activity cytoplasm ->
intracellular
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
intracellular CIN5, YAP6
YNR035C ARC35 cell growth and/or maintenance ->
cell growth and/or maintenance structural molecule activity ->
structural molecule activity Arp2/3 protein complex ->
intracellular ABF1
YAL022C FUN26 nucleoside transport ->
cell growth and/or maintenance nucleoside transporter activity ->
nucleoside transporter activity intracellular, membrane ->
intracellular, membrane ADR1, FHL1, FZF1, IME4, MAC1, MATa1, NRG1, PDR1, SFP1, SMP1, STB1, SWI5, YFL044C
YOL122C SMF1 manganese ion transport ->
cell growth and/or maintenance manganese ion transporter activity ->
manganese ion transporter activity plasma membrane, vacuole (sensu Fungi) ->
membrane, intracellular
YKL170W MRPL38 protein biosynthesis ->
biosynthesis, protein metabolism structural molecule activity ->
structural molecule activity mitochondrial large ribosomal subunit ->
intracellular FKH1
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity CRZ1
Main: biosynthesis (0.43) structural molecule activity (0.29) intracellular (1.00) ABF1 (0.20)
Score: 0.33 0.05 1.00 0.000
P-value: 2.556E-01 (amino acid biosynthesis) 1.305E-01 (lyase activity) 2.261E-01 (mitochondrial matrix) 6.406E-01 (ADR1)

MCM1'(1) AND m_other_morphogenetic_activities_orfnum2SD_n7(1) AND HSE(1) => SimExpr(YDR116C) OR SimExpr(other) : 6 2

EXPR: (0.209) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) HSE (P < 0.004) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
|YDL020C| RPN4 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus ABF1, CBF1, HSF1, PUT3, YAP1
YHR074W QNS1 NAD+ synthase (glutamine-hydrolyzing) activity ->
NAD+ synthase (glutamine-hydrolyzing) activity USV1
|YDR293C| SSD1 cell wall organization and biogenesis ->
cell organization and biogenesis RNA binding ->
RNA binding cytoplasm ->
cytoplasm
YGR284C ERV29 ER to Golgi transport ->
transport, vesicle-mediated transport COPII-coated vesicle ->
cytoplasm HSF1
YOR137C SIA1 proton transport ->
transport HIR1, SMP1
YKL164C PIR1 intracellular protein transport, cell wall organization and biogenesis ->
cell organization and biogenesis, transport structural constituent of cell wall ->
structural constituent of cell wall cell wall ->
cell wall BAS1, MCM1, PHD1, SMP1, SWI5
YDR116C MRPL1 protein biosynthesis, meiosis, aerobic respiration ->
biosynthesis, cell proliferation, energy pathways, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex CHA4, GRF10(Pho2)
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
Main: cell organization and biogenesis (0.43) structural constituent of cell wall (0.17) cytoplasm (0.67) SMP1 (0.43)
Score: 0.33 0.00 0.47 0.190
P-value: 4.643E-01 (external encapsulating structure organization and biogenesis) 8.208E-01 (structural molecule activity) 4.706E+00 (cytoplasm) 4.323E-03 (SMP1)

m_osmosensing_orfnum2SD_n6(1) AND PHO(1) => SimExpr(YLR333C) OR SimExpr(other) : 6 2

SFF(1) AND m_lysosomal_and_vacuolar_degradation_orfnum2SD_n3(1) AND mRRPE(1) => SimExpr(YLR333C) OR SimExpr(other) : 5 1

EXPR: (0.198) SFF (P < 0.000) mRRPE (P < 0.000) m_lysosomal_and_vacuolar_degradation_orfnum2SD_n3 (P < 0.009)

ORF SYMBOL P F C TF
|YGR144W| THI4 DNA repair, thiamin biosynthesis ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, vitamin metabolism mitochondrion ->
cytoplasm ABF1, CIN5
YOL103W ITR2 myo-inositol transport ->
transport myo-inositol transporter activity ->
myo-inositol transporter activity membrane ->
membrane DIG1, MTH1
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YLR333C RPS25B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, RAP1
YMR012W CLU1 mitochondrion organization and biogenesis, translational initiation ->
cell organization and biogenesis, biosynthesis, protein metabolism eukaryotic translation initiation factor 3 complex, cytoplasm ->
cytoplasm
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
Main: biosynthesis (0.67) electron transporter activity (0.25) cytoplasm (0.60) ABF1 (0.40)
Score: 0.47 0.00 0.30 0.100
P-value: 1.210E-01 (mitochondrion organization and biogenesis) 4.458E-01 (transporter activity) 4.382E-02 (eukaryotic 43S pre-initiation complex) 8.306E-01 (ABF1)

m_anion_transporters_orfnum2SD_n15(1) AND m_cytokinesis_orfnum2SD_n11(1) => SimExpr(YKL211C) OR SimExpr(other) : 6 1

m_other_energy_generation_activities_orfnum2SD_n9(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YKL211C) OR SimExpr(other) : 6 1

m_g-proteins_orfnum2SD_n11(1) AND m_peroxisomal_transport_orfnum2SD_n19(1) => SimExpr(YKL211C) OR SimExpr(other) : 6 2

ABF1(1) AND m_phosphate_transport_orfnum2SD_n8(1) => SimExpr(YKL211C) OR SimExpr(other) : 6 3

EXPR: (0.243) m_phosphate_transport_orfnum2SD_n8 (P < 0.032) ABF1 (P < 0.035)

ORF SYMBOL P F C TF
YLR192C HCR1 protein biosynthesis ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity eukaryotic translation initiation factor 3 complex ->
cytoplasm ABF1
YAL011W SWC1 MIG1
YLR264W RPS28B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex ABF1, FHL1, GCR2
YDR034C LYS14 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis transcriptional activator activity ->
transcriptional activator activity nucleus ->
nucleus NDD1
YNL183C NPR1 regulation of nitrogen utilization ->
nitrogen metabolism kinase activity ->
kinase activity cytoplasm ->
cytoplasm ABF1
|YJR017C| ESS1 mRNA processing, negative regulation of phosphorylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, phosphorus metabolism, regulation of metabolism peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity nucleus ->
nucleus
|YNL201C| PSY2
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity CRZ1
|YFR020W| NO SYMBOL MIG1
Main: biosynthesis (0.67) peptidyl-prolyl cis-trans isomerase activity (0.17) cytoplasm (0.60) ABF1 (0.43)
Score: 0.40 0.00 0.40 0.190
P-value: 3.730E-01 (amino acid biosynthesis) 2.786E+00 (enzyme activity) 1.175E-01 (eukaryotic 43S pre-initiation complex) 2.108E-02 (MIG1)

m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) AND m_anion_transporters_orfnum2SD_n23(1) => SimExpr(YKL211C) OR SimExpr(other) : 11 4

EXPR: (0.234) m_allantoin_and_allantoate_transporters_orfnum2SD_n13 (P < 0.001) m_anion_transporters_orfnum2SD_n23 (P < 0.006)

ORF SYMBOL P F C TF
YKR095W MLP1 protein-nucleus import ->
protein metabolism, transport nuclear membrane, nucleoplasm ->
nucleus, endomembrane system FHL1, RAP1
|YOL119C| MCH4 transport ->
transport monocarboxylic acid transporter activity, transporter activity ->
transporter activity vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole CAD1, YAP1
YHR076W PTC7 protein phosphatase type 2C activity ->
hydrolase activity\, acting on ester bonds mitochondrion ->
cytoplasm
|YOR374W| ALD4 ethanol metabolism ->
alcohol metabolism aldehyde dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors mitochondrion ->
cytoplasm RAP1
YKR039W GAP1 amino acid transport ->
transport general amino acid permease activity ->
transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane CIN5, YAP6
YMR291W NO SYMBOL RAP1
YIL052C RPL34B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex RME1
|YKR072C| SIS2 G1/S transition of mitotic cell cycle, salinity response, regulation of mitotic cell cycle, coenzyme A biosynthesis ->
response to abiotic stimulus, biosynthesis, coenzymes and prosthetic group metabolism, cell proliferation protein phosphatase inhibitor activity, phosphopantothenoylcysteine decarboxylase activity ->
protein phosphatase regulator activity, carbon-carbon lyase activity nucleus, cytoplasm ->
nucleus, cytoplasm
YNR047W NO SYMBOL MIG1
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
carbon-carbon lyase activity CRZ1
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
hydrolase activity\, acting on ester bonds alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
YNL045W NO SYMBOL MSN1
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
transferase activity\, transferring phosphorus-containing groups MTH1
|YIL166C| NO SYMBOL GRF10(Pho2)
YNL192W CHS1 budding ->
asexual reproduction chitin synthase activity ->
transferase activity\, transferring glycosyl groups plasma membrane, chitosome ->
plasma membrane, cytoplasm STE12, SWI4, SWI5
Main: biosynthesis (0.30) carbon-carbon lyase activity (0.20) cytoplasm (0.67) RAP1 (0.25)
Score: 0.22 0.07 0.47 0.045
P-value: 4.459E-01 (response to stress) 8.896E-02 (carboxy-lyase activity) 2.278E+00 (plasma membrane) 8.691E-01 (RAP1)

m_PNDE6(1) AND m_organization_of_golgi_orfnum2SD_n7(1) => SimExpr(YNL068C) : 6

EXPR: (0.170) m_organization_of_golgi_orfnum2SD_n7 (P < 0.000) m_PNDE6 (P < 0.000)

ORF SYMBOL P F C TF
YML043C RRN11 transcription from Pol I promoter ->
transcription RNA polymerase I transcription factor activity ->
RNA polymerase I transcription factor activity RNA polymerase I transcription factor complex ->
nucleus MAL13
YMR070W MOT3 transcription ->
transcription transcriptional repressor activity, DNA binding, transcriptional activator activity ->
transcriptional repressor activity, DNA binding, transcriptional activator activity nucleus ->
nucleus BAS1, CUP9, HSF1, INO2, INO4, SWI4
YIL135C VHS2 G1/S transition of mitotic cell cycle ->
cell cycle ABF1, DAL82, INO2, MAC1, MTH1, ROX1
YOR287C NO SYMBOL
YNL068C FKH2 G2-specific transcription in mitotic cell cycle, pseudohyphal growth, regulation of cell cycle ->
cellular morphogenesis, cell cycle, regulation of transcription, transcription transcription factor activity ->
DNA binding nucleus ->
nucleus FHL1, RAP1
YKL126W YPK1 protein amino acid phosphorylation, sphingolipid metabolism, endocytosis ->
phosphate metabolism, membrane lipid metabolism, vesicle-mediated transport, protein modification protein serine/threonine kinase activity ->
transferase activity\, transferring phosphorus-containing groups plasma membrane, cytosol, bud neck ->
plasma membrane, cytoplasm, site of polarized growth (sensu Fungi)
Main: transcription (0.60) DNA binding (0.50) nucleus (0.75) INO2 (0.50)
Score: 0.40 0.17 0.50 0.167
P-value: 3.355E-01 (transcription) 6.045E-02 (transcription regulator activity) 1.786E+00 (nucleus) 4.701E-02 (INO2)

m_ion_transporters_orfnum2SD_n11(1) AND m_nitrogen_and_sulphur_utilization_orfnum2SD_n4(1) => SimExpr(YOR317W) OR SimExpr(other) : 7 3

EXPR: (0.237) m_nitrogen_and_sulphur_utilization_orfnum2SD_n4 (P < 0.025) m_ion_transporters_orfnum2SD_n11 (P < 0.015)

ORF SYMBOL P F C TF
|YDL049C| KNH1 beta-1\,6 glucan biosynthesis ->
biosynthesis, carbohydrate metabolism extracellular, cell wall (sensu Fungi) ->
extracellular, cell wall FKH1, INO2, INO4, SKN7
YGL006W PMC1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium-transporting ATPase activity ->
purine nucleotide binding, cation transporter activity, primary active transporter activity, hydrolase activity\, acting on acid anhydrides, metal ion transporter activity vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole SKN7
|YGR144W| THI4 DNA repair, thiamin biosynthesis ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, vitamin metabolism mitochondrion ->
cytoplasm ABF1, CIN5
YGR065C VHT1 biotin transport ->
transport biotin transporter activity ->
biotin transporter activity plasma membrane ->
plasma membrane
YGR121C MEP1 ammonium transport ->
transport ammonium transporter activity ->
cation transporter activity plasma membrane ->
plasma membrane CIN5
|YNL216W| RAP1 chromatin silencing, transcription from Pol III promoter, telomerase-dependent telomere maintenance, chromatin silencing at telomere ->
cell organization and biogenesis, response to DNA damage, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity, DNA binding ->
DNA binding nucleus, nuclear telomere cap complex, nuclear telomeric heterochromatin ->
nucleus, nuclear chromatin, chromosome RAP1
YPL219W PCL8 regulation of glycogen catabolism, regulation of glycogen biosynthesis ->
carbohydrate metabolism, catabolism, biosynthesis, polysaccharide metabolism, energy pathways, regulation of metabolism cyclin-dependent protein kinase\, regulator activity ->
transferase activity\, transferring phosphorus-containing groups, protein kinase regulator activity cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex
YMR297W PRC1 vacuolar protein catabolism ->
catabolism, protein metabolism carboxypeptidase C activity ->
peptidase activity cytoplasm, endoplasmic reticulum ->
cytoplasm ABF1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides plasma membrane ->
plasma membrane ACE2, SKN7
YOR317W FAA1 N-terminal protein myristoylation, lipid metabolism, lipid transport ->
biosynthesis, lipid metabolism, transport, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
ligase activity\, forming carbon-sulfur bonds lipid particle ->
cytoplasm ASH1, CIN5, HSF1, INO4, RAP1
Main: biosynthesis (0.40) hydrolase activity\, acting on acid anhydrides (0.25) cytoplasm (0.40) SKN7 CIN5 (0.38)
Score: 0.36 0.07 0.20 0.321
P-value: 2.148E-02 (glucan biosynthesis) 4.611E-01 (cation transporter activity) 1.582E-01 (plasma membrane) 5.008E-02 (SKN7)

m_cytokinesis_orfnum2SD_n11(1) AND m_nitrogen_and_sulphur_utilization_orfnum2SD_n4(1) => SimExpr(YOR317W) OR SimExpr(other) : 5 1

m_transport_atpases_orfnum2SD_n17(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YOR317W) OR SimExpr(other) : 5 1

EXPR: (0.200) m_transport_atpases_orfnum2SD_n17 (P < 0.000) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.008)

ORF SYMBOL P F C TF
YOL087C NO SYMBOL DAL82
YKR003W OSH6 steroid biosynthesis ->
biosynthesis, lipid metabolism oxysterol binding ->
oxysterol binding
|YJR095W| SFC1 fumarate transport, succinate transport ->
transport succinate/fumarate antiporter activity ->
succinate/fumarate antiporter activity mitochondrial inner membrane ->
cytoplasm, membrane CBF1, PHD1
YGR267C FOL2 folic acid and derivative biosynthesis ->
aromatic compound metabolism, biosynthesis, coenzymes and prosthetic group metabolism, heterocycle metabolism, organic acid metabolism GTP cyclohydrolase I activity ->
GTP cyclohydrolase I activity cytoplasm ->
cytoplasm GCN4
YLR205C HMX1 iron ion homeostasis ->
cell homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
YOR317W FAA1 N-terminal protein myristoylation, lipid metabolism, lipid transport ->
biosynthesis, lipid metabolism, transport, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
long-chain-fatty-acid-CoA-ligase activity lipid particle ->
cytoplasm ASH1, CIN5, HSF1, INO4, RAP1
Main: biosynthesis (0.60) succinate/fumarate antiporter activity (0.20) cytoplasm (0.75) DAL82 (0.20)
Score: 0.40 0.00 0.67 0.000
P-value: 2.401E-01 (lipid metabolism) 2.408E+00 (binding) 2.499E+00 (membrane) 6.950E-01 (ASH1)

m_g-proteins_orfnum2SD_n13(1) AND REB1(1) => SimExpr(YDR003W) OR SimExpr(other) : 7 2

m_osmosensing_orfnum2SD_n6(1) AND m_g-proteins_orfnum2SD_n11(1) AND m_anion_transporters_orfnum2SD_n22(1) => SimExpr(YJR044C) OR SimExpr(other) : 5 2

EXPR: (0.229) m_g-proteins_orfnum2SD_n11 (P < 0.020) m_osmosensing_orfnum2SD_n6 (P < 0.004) m_anion_transporters_orfnum2SD_n22 (P < 0.020)

ALPHA2(1) AND SWI5(1) AND REB1(1) => SimExpr(YOR025W) : 5

EXPR: (0.181) SWI5 (P < 0.000) REB1 (P < 0.004) ALPHA2 (P < 0.001)

m_osmosensing_orfnum2SD_n6(1) AND m_RRSE3(1) AND PAC(1) => SimExpr(YGR245C) OR SimExpr(other) : 6 1

EXPR: (0.212) m_RRSE3 (P < 0.000) PAC (P < 0.003) m_osmosensing_orfnum2SD_n6 (P < 0.000)

ORF SYMBOL P F C TF
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle nucleus ->
nucleus
YNL132W KRE33
|YFR017C| NO SYMBOL ACE2, FKH2, IME4, MBP1, NDD1, NRG1, PDR1, RME1, SFP1, SKN7, SRD1, SWI4, SWI5
YJL010C NO SYMBOL
YGR162W TIF4631 translational initiation ->
translational initiation translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex HSF1
YNL292W PUS4 tRNA modification ->
tRNA modification pseudouridylate synthase activity ->
pseudouridylate synthase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YGR272C NO SYMBOL REB1, STP2
Main: start control point of mitotic cell cycle (0.33) translation initiation factor activity (0.50) cytoplasm (0.67) SWI4 (0.25)
Score: 0.00 0.00 0.67 0.000
P-value: 3.979E+00 (metabolism) 2.000E+00 4.624E+00 (nucleus) 1.000E+00

m_osmosensing_orfnum2SD_n6(1) AND m_RRSE3(1) AND PAC(1) AND mRRPE(1) => SimExpr(YGR245C) : 5

EXPR: (0.174) mRRPE (P < 0.000) m_RRSE3 (P < 0.000) PAC (P < 0.000) m_osmosensing_orfnum2SD_n6 (P < 0.000)

ORF SYMBOL P F C TF
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle nucleus ->
nucleus
YNL132W KRE33
YGR162W TIF4631 translational initiation ->
translational initiation translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex HSF1
YNL292W PUS4 tRNA modification ->
tRNA modification pseudouridylate synthase activity ->
pseudouridylate synthase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YGR272C NO SYMBOL REB1, STP2
Main: start control point of mitotic cell cycle (0.33) translation initiation factor activity (0.50) cytoplasm (0.67) HSF1 (0.33)
Score: 0.00 0.00 0.67 0.000
P-value: 3.848E+00 (metabolism) 2.000E+00 3.457E+00 (nucleus) 2.022E-01 (STP2)

m_g-proteins_orfnum2SD_n11(1) AND ALPHA1'(1) AND m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9(1) => SimExpr(YAL061W) OR SimExpr(other) : 6 2

EXPR: (0.211) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9 (P < 0.011) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
YMR002W NO SYMBOL NDD1, REB1, SWI6
YAL022C FUN26 nucleoside transport ->
nucleoside transport nucleoside transporter activity ->
nucleoside transporter activity intracellular, membrane ->
intracellular, membrane ADR1, FHL1, FZF1, IME4, MAC1, MATa1, NRG1, PDR1, SFP1, SMP1, STB1, SWI5, YFL044C
|YMR199W| CLN1 regulation of CDK activity ->
regulation of CDK activity cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity nucleus, cytoplasm ->
intracellular FKH2, MBP1, NDD1, SKN7, STE12, SWI4, SWI6
YPL111W CAR1 arginine catabolism to ornithine ->
arginine catabolism to ornithine arginase activity ->
arginase activity cytosol ->
intracellular GCN4
YAL061W NO SYMBOL
YAR060C NO SYMBOL
|YDR100W| TVP15 RAP1
YHR212C NO SYMBOL
Main: nucleoside transport (0.33) cyclin-dependent protein kinase\, regulator activity (0.33) intracellular (1.00) SWI6 NDD1 (0.40)
Score: 0.00 0.00 1.00 0.100
P-value: 4.877E+00 (cell growth and/or maintenance) 2.919E+00 (enzyme activity) 4.937E+00 (cytoplasm) 4.837E-01 (NDD1)

RAP1(1) AND m_peroxisomal_organization_orfnum2SD_n28(1) => SimExpr(YIL018W) OR SimExpr(other) : 5 2

EXPR: (0.184) RAP1 (P < 0.211) m_peroxisomal_organization_orfnum2SD_n28 (P < 0.001)

RAP1(1) AND m_other_mrna-transcription_activities_orfnum2SD_n20(1) => SimExpr(YIL018W) OR SimExpr(other) : 8 2

RAP1(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn(1) => SimExpr(YIL018W) OR SimExpr(other) : 6 1

m_amino-acid_transport_orfnum2SD_n20(1) AND m_RPE34(1) => SimExpr(YIL018W) OR SimExpr(other) : 7 1

RAP1(1) AND MCM1'(1) => SimExpr(YIL018W) OR SimExpr(other) : 18 2

RAP1(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YIL018W) OR SimExpr(other) : 8 3

RAP1(1) AND m_RPE6(1) => SimExpr(YIL018W) : 9

m_RPE69(1) AND m_RPE34(1) => SimExpr(YIL018W) : 5

RAP1(1) AND m_RPE8(1) => SimExpr(YIL018W) : 9

m_RPE6(1) AND m_RPE8(1) => SimExpr(YIL018W) : 8

m_RPE72(1) AND m_RPE8(1) => SimExpr(YIL018W) : 5

RAP1(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YIL018W) : 8

RAP1(1) AND m_RPE34(1) => SimExpr(YIL018W) : 8

m_RPE6(1) AND m_RPE34(1) => SimExpr(YIL018W) : 6

RAP1(1) AND m_RPE72(1) => SimExpr(YIL018W) : 5

EXPR: (0.111) m_RPE72 (P < 0.000) RAP1 (P < 0.014)

m_RPE6(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YIL018W) : 7

RAP1(1) AND m_RPE69(1) => SimExpr(YIL018W) : 6

m_organization_of_cytoplasm_orfnum2SD_n27(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YIL018W) : 5

MCM1'(1) AND m_MERE4(1) AND m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9(1) => SimExpr(YDR074W) OR SimExpr(other) : 5 2

EXPR: (0.188) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9 (P < 0.003) m_MERE4 (P < 0.000) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
|YNL208W| NO SYMBOL INO2
|YKL035W| UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
nucleotidyltransferase activity
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in linear amidines cytosol ->
cytoplasm GCN4
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
phosphoric ester hydrolase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
YOR299W BUD7 bud site selection ->
cell proliferation, cell organization and biogenesis HSF1, MTH1
YIL124W AYR1 phosphatidic acid biosynthesis ->
biosynthesis, membrane lipid metabolism, organic acid metabolism, lipid metabolism acylglycerone-phosphate reductase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor endoplasmic reticulum, lipid particle, cytoplasm ->
cytoplasm
Main: carbohydrate metabolism (0.50) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.40) cytoplasm (0.75) ACE2 (0.25)
Score: 0.40 0.10 0.50 0.000
P-value: 6.336E-02 (carbohydrate metabolism) 7.413E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 4.385E+00 (cytoplasm) 5.694E-01 (ADR1)

m_other_nutritional-response_activities_orfnum2SD_n11(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YDR074W) OR SimExpr(other) : 5 1

EXPR: (0.195) m_other_nutritional-response_activities_orfnum2SD_n11 (P < 0.008) m_anion_transporters_orfnum2SD_n20 (P < 0.006)

ORF SYMBOL P F C TF
YAL039C CYC3 cytochrome c-heme linkage ->
protein metabolism holocytochrome c synthase activity ->
holocytochrome c synthase activity mitochondrial intermembrane space ->
cytoplasm
|YNL144C| NO SYMBOL RAP1
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
trehalose phosphatase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
YNL015W PBI2 regulation of proteolysis and peptidolysis, vacuole fusion (non-autophagic) ->
cell organization and biogenesis, catabolism, protein metabolism, regulation of metabolism endopeptidase inhibitor activity ->
endopeptidase inhibitor activity cytoplasm, vacuole (sensu Fungi) ->
cytoplasm INO4
YGR212W NO SYMBOL GCR2
YIL124W AYR1 phosphatidic acid biosynthesis ->
biosynthesis, membrane lipid metabolism, organic acid metabolism, lipid metabolism acylglycerone-phosphate reductase activity ->
acylglycerone-phosphate reductase activity endoplasmic reticulum, lipid particle, cytoplasm ->
cytoplasm
Main: protein metabolism (0.50) acylglycerone-phosphate reductase activity (0.25) cytoplasm (0.75) GCR2 (0.33)
Score: 0.17 0.00 0.50 0.000
P-value: 2.642E+00 (protein metabolism) 2.077E+00 (enzyme activity) 3.918E+00 (cytoplasm) 3.530E-01 (GCR2)

m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YDR074W) : 5

EXPR: (0.157) m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8 (P < 0.003) m_anion_transporters_orfnum2SD_n20 (P < 0.000)

m_amino-acid_degradation_orfnum2SD_n8(1) AND m_g-proteins_orfnum2SD_n12(1) AND m_phosphate_transport_orfnum2SD_n8(1) AND ALPHA1'(1) => SimExpr(YIL052C) OR SimExpr(other) : 5 2

EXPR: (0.209) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_phosphate_transport_orfnum2SD_n8 (P < 0.001) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.002) ALPHA1' (P < 0.001)

ORF SYMBOL P F C TF
YPL131W RPL5 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1
|YGL071W| RCS1 positive regulation of transcription from Pol II promoter, high affinity iron ion transport ->
transport, ion transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity ->
transcription factor activity nucleus, cytoplasm ->
nucleus, cytoplasm HSF1, RAP1, RCS1
|YDL078C| MDH3 glyoxylate cycle, malate metabolism, fatty acid beta-oxidation, NADH regeneration ->
aldehyde metabolism, carbohydrate metabolism, lipid metabolism, coenzymes and prosthetic group metabolism, organic acid metabolism, vitamin metabolism, energy pathways malic enzyme activity ->
malic enzyme activity peroxisomal matrix ->
cytoplasm MIG1
YJR148W BAT2 branched chain family amino acid biosynthesis, amino acid catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis, catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity cytoplasm ->
cytoplasm NDD1, SKN7, SWI4
YIL052C RPL34B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex RME1
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
YOR264W DSE3 SWI5
Main: biosynthesis (0.50) structural constituent of ribosome (0.33) cytoplasm (0.83) SWI5 RAP1 (0.29)
Score: 0.40 0.07 0.73 0.095
P-value: 1.143E+00 (organic acid metabolism) 5.303E-01 (structural constituent of ribosome) 1.287E-01 (cytosolic large ribosomal subunit (sensu Eukarya)) 1.236E-01 (SWI5)

m_RPE6(1) AND LYS14(1) => SimExpr(YIL052C) OR SimExpr(other) : 5 1

EXPR: (0.167) LYS14 (P < 0.000) m_RPE6 (P < 0.166)

m_RPE6(1) AND m_RPE21(1) => SimExpr(YIL052C) : 5

m_LFTE17(1) AND m_ion_transporters_orfnum2SD_n14(1) => SimExpr(YOR286W) OR SimExpr(other) : 5 1

EXPR: (0.188) m_LFTE17 (P < 0.001) m_ion_transporters_orfnum2SD_n14 (P < 0.018)

ORF SYMBOL P F C TF
YPR036W VMA13 vacuolar acidification ->
cell homeostasis, cell organization and biogenesis, transport hydrogen-exporting ATPase activity ->
hydrogen-exporting ATPase activity hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole
YOR286W NO SYMBOL
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
|YGR008C| STF2 response to dessication, ATP synthesis coupled proton transport ->
response to abiotic stimulus, transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane INO2
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
trehalose phosphatase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
YIL133C RPL16A protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, PUT3, RAP1, RGM1, SFP1, SMP1, YAP5
Main: biosynthesis (0.40) RNA binding (0.25) cytoplasm (0.80) INO2 (0.67)
Score: 0.20 0.00 0.60 0.333
P-value: 4.610E-01 (response to stress) 1.646E+00 (binding) 6.209E-01 (ribosome) 3.694E-02 (INO2)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_glyoxylate_cycle_orfnum2SD_n11(1) AND m_ion_transporters_orfnum2SD_n14(1) => SimExpr(YOR286W) OR SimExpr(other) : 6 1

EXPR: (0.193) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) m_ion_transporters_orfnum2SD_n14 (P < 0.013) m_glyoxylate_cycle_orfnum2SD_n11 (P < 0.000)

ORF SYMBOL P F C TF
YOR286W NO SYMBOL
YLR249W YEF3 translational elongation ->
translational elongation translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YOR316C COT1 cobalt ion transport, zinc ion transport, zinc ion homeostasis ->
cobalt ion transport, zinc ion transport, zinc ion homeostasis di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity ->
di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity vacuole (sensu Fungi) ->
cytoplasm FKH2, INO2, INO4, NDD1, RAP1
YKL128C PMU1 INO4
YPL111W CAR1 arginine catabolism to ornithine ->
arginine catabolism to ornithine arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
|YOR338W| NO SYMBOL RAP1
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
trehalose phosphatase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
Main: response to stress (0.25) translation elongation factor activity (0.25) cytoplasm (0.75) INO4 (0.60)
Score: 0.00 0.00 0.50 0.400
P-value: 3.852E+00 (metabolism) 1.611E+00 (hydrolase activity) 4.385E+00 (cytoplasm) 4.221E-03 (INO4)

m_g-proteins_orfnum2SD_n11(1) AND CSRE(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YKL120W) OR SimExpr(other) : 7 3

EXPR: (0.248) m_g-proteins_orfnum2SD_n11 (P < 0.010) m_anion_transporters_orfnum2SD_n15 (P < 0.029) CSRE (P < 0.013)

m_regulation_of_amino-acid_metabolism_orfnum2SD_n10(1) AND m_drug_transporters_orfnum2SD_n7(1) => SimExpr(YKL120W) OR SimExpr(other) : 5 2

EXPR: (0.213) m_regulation_of_amino-acid_metabolism_orfnum2SD_n10 (P < 0.004) m_drug_transporters_orfnum2SD_n7 (P < 0.005)

ORF SYMBOL P F C TF
YPL250C ICY2 HSF1, MET4
YOL012C HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleoplasm, chromatin, nuclear chromosome SWI4
YLR460C NO SYMBOL CIN5, HAL9, YAP1
|YOR161C| NO SYMBOL FHL1, PHD1, RAP1
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
carnitine metabolism, alcohol metabolism carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity mitochondrion ->
mitochondrion
|YKL069W| NO SYMBOL
YKL120W OAC1 oxaloacetate transport, sulfate transport ->
oxaloacetate transport, sulfate transport oxaloacetate carrier activity, sulfate porter activity ->
oxaloacetate carrier activity, sulfate porter activity mitochondrial inner membrane ->
mitochondrion, inner membrane LEU3, MTH1
Main: oxaloacetate transport (0.33) oxaloacetate carrier activity (0.33) mitochondrion (0.67) YAP1 (0.20)
Score: 0.00 0.00 0.33 0.000
P-value: 5.723E+00 (cell growth and/or maintenance) 2.000E+00 1.397E+00 (mitochondrion) 8.331E-01 (LEU3)

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND CSRE(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YKL120W) : 6

EXPR: (0.184) m_anion_transporters_orfnum2SD_n15 (P < 0.000) m_metabolism_of_energy_reserves_orfnum2SD_n8 (P < 0.000) CSRE (P < 0.000)

ORF SYMBOL P F C TF
YOR312C RPL20B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, FKH2, GAT3, RAP1
YJL042W MHP1 microtubule stabilization, cell wall organization and biogenesis ->
microtubule stabilization, cell wall organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton microtubule ->
cytoplasm CRZ1, GAL4, GAT3, PDR1, RGM1, YAP5
YNL208W NO SYMBOL INO2
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
carnitine metabolism, alcohol metabolism carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity mitochondrion ->
cytoplasm
YKL120W OAC1 oxaloacetate transport, sulfate transport ->
oxaloacetate transport, sulfate transport oxaloacetate carrier activity, sulfate porter activity ->
oxaloacetate carrier activity, sulfate porter activity mitochondrial inner membrane ->
cytoplasm, inner membrane LEU3, MTH1
Main: oxaloacetate transport (0.20) ubiquinol-cytochrome c reductase activity (0.20) cytoplasm (1.00) GAT3 (0.40)
Score: 0.00 0.00 1.00 0.100
P-value: 5.485E+00 (metabolism) 1.112E-01 (cation transporter activity) 2.146E-01 (mitochondrial inner membrane) 5.510E-02 (GAT3)

m_other_cell_rescue_activities_orfnum2SD_n10(1) AND m_anion_transporters_orfnum2SD_n9(1) => SimExpr(YIR023W) OR SimExpr(other) : 5 1

ALPHA1(1) AND MCB(1) => SimExpr(YGR109C) OR SimExpr(other) : 22 10

BAS1(1) AND MCB(1) => SimExpr(YGR109C) OR SimExpr(other) : 5 1

MCM1(1) AND MCB(1) => SimExpr(YGR109C) OR SimExpr(other) : 7 2

EXPR: (0.199) MCB (P < 0.105) MCM1 (P < 0.000)

ORF SYMBOL P F C TF
|YNR028W| CPR8 peptidyl-prolyl cis-trans isomerase activity ->
cis-trans isomerase activity ASH1, DIG1, MCM1
YGR109C CLB6 regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis ->
cell cycle, mitotic cell cycle, DNA metabolism cyclin-dependent protein kinase\, regulator activity ->
transferase activity\, transferring phosphorus-containing groups, protein kinase regulator activity MBP1, STB1, SWI4, SWI6
YGL163C RAD54 double-strand break repair via synthesis-dependent strand annealing, heteroduplex formation, double-strand break repair via break-induced replication, telomerase-independent telomere maintenance, double-strand break repair via single-strand annealing, chromatin modeling ->
mating-type switching/recombination, chromosome organization and biogenesis (sensu Eukarya), DNA repair, response to DNA damage, DNA metabolism DNA supercoiling activity, DNA dependent ATPase activity ->
DNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleus ->
nucleus
YKR077W NO SYMBOL
YGR189C CRH1 cell wall, incipient bud site ->
cell wall, incipient bud site GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YDR279W RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
|YIL066C| RNR3 DNA replication ->
cell cycle, DNA metabolism ribonucleoside-diphosphate reductase activity ->
oxidoreductase activity\, acting on CH2 groups cytoplasm ->
cytoplasm RFX1, STB1
YDR309C GIC2 axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) ->
budding, intracellular signaling cascade, cytoplasm organization and biogenesis small GTPase regulatory/interacting protein activity ->
small GTPase regulatory/interacting protein activity actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site ->
cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6
YML027W YOX1 negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
regulation of transcription, M phase, transcription, cell cycle specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding nucleus ->
nucleus MBP1, SWI4, SWI6
Main: DNA metabolism (0.60) DNA binding (0.33) cytoplasm (0.40) MBP1 (0.71)
Score: 0.50 0.07 0.30 0.619
P-value: 4.056E-01 (mitotic cell cycle) 7.505E-01 (DNA binding) 5.771E-03 (incipient bud site) 5.451E-05 (MBP1)

MCM1'(1) AND m_anion_transporters_orfnum2SD_n15(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn(1) => SimExpr(YPL090C) OR SimExpr(other) : 5 1

EXPR: (0.199) m_anion_transporters_orfnum2SD_n15 (P < 0.004) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn (P < 0.003) MCM1' (P < 0.000)

m_RPE8(1) AND CSRE(1) => SimExpr(YPL090C) OR SimExpr(other) : 11 4

m_homeostasis_of_metal_ions_orfnum2SD_n20(1) AND m_RPE8(1) => SimExpr(YPL090C) OR SimExpr(other) : 5 1

RAP1(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YPL090C) OR SimExpr(other) : 8 2

RAP1(1) AND m_other_energy_generation_activities_orfnum2SD_n9(1) => SimExpr(YPL090C) OR SimExpr(other) : 6 2

EXPR: (0.179) RAP1 (P < 0.164) m_other_energy_generation_activities_orfnum2SD_n9 (P < 0.000)

RAP1(1) AND CSRE(1) => SimExpr(YPL090C) OR SimExpr(other) : 12 2

RAP1(1) AND m_homeostasis_of_metal_ions_orfnum2SD_n20(1) => SimExpr(YPL090C) OR SimExpr(other) : 5 1

RAP1(1) AND m_RPE8(1) => SimExpr(YPL090C) : 9

RAP1(1) AND m_RPE69(1) => SimExpr(YPL090C) : 6

m_RPE69(1) AND m_RPE34(1) => SimExpr(YPL090C) : 5

m_RPE69(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YPL090C) : 5

EXPR: (0.150) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) m_RPE69 (P < 0.098)

RAP1(1) AND m_RPE34(1) => SimExpr(YPL090C) : 8

RAP1(1) AND m_trna_processing_orfnum2SD_n6(1) => SimExpr(YOL121C) OR SimExpr(other) : 5 2

EXPR: (0.183) RAP1 (P < 0.249) m_trna_processing_orfnum2SD_n6 (P < 0.000)

m_RPE57(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n8.scn(1) => SimExpr(YOL121C) OR SimExpr(other) : 6 1

RAP1(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YOL121C) OR SimExpr(other) : 8 3

RAP1(1) AND mRRPE(1) => SimExpr(YOL121C) OR SimExpr(other) : 7 3

RAP1(1) AND m_RPE57(1) => SimExpr(YOL121C) : 8

m_RPE6(1) => SimExpr(YOR063W) OR SimExpr(other) : 18 8

EXPR: (0.200) m_RPE6 (P < 0.547)

m_RPE6(1) AND CSRE(1) => SimExpr(YOR063W) : 11

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND mRRPE(1) AND CCA(1) => SimExpr(YDR374C) OR SimExpr(other) : 5 2

EXPR: (0.239) CCA (P < 0.002) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) mRRPE (P < 0.000)

ORF SYMBOL P F C TF
|YLR328W| NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzyme metabolism, water-soluble vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity CIN5, MSN1, ROX1
YPL186C UIP4 nuclear membrane ->
nucleus, endomembrane system RIM101, USV1
YGR144W THI4 DNA repair, thiamin biosynthesis ->
DNA metabolism, vitamin biosynthesis, water-soluble vitamin metabolism mitochondrion ->
cytoplasm ABF1, CIN5
YOR339C UBC11 protein polyubiquitination, protein monoubiquitination ->
macromolecule catabolism, protein modification, protein metabolism ubiquitin conjugating enzyme activity ->
ubiquitin conjugating enzyme activity cytoplasm ->
cytoplasm HAP2, IXR1
YDR374C NO SYMBOL RME1
YPL060W LPE10 mitochondrial magnesium ion transport ->
intracellular transport, ion transport magnesium ion transporter activity ->
magnesium ion transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane HIR2
|YMR116C| ASC1 cytoplasm ->
cytoplasm FHL1, RAP1
Main: water-soluble vitamin metabolism (0.50) nicotinamide-nucleotide adenylyltransferase activity (0.33) cytoplasm (0.80) CIN5 (0.29)
Score: 0.17 0.00 0.60 0.048
P-value: 3.732E-02 (water-soluble vitamin metabolism) 2.849E+00 (enzyme activity) 1.630E+00 (mitochondrion) 3.568E-01 (MSN1)

m_phosphate_transport_orfnum2SD_n8(1) AND PDR(1) => SimExpr(YNL008C) OR SimExpr(other) : 8 3

EXPR: (0.227) m_phosphate_transport_orfnum2SD_n8 (P < 0.002) PDR (P < 0.001)

ORF SYMBOL P F C TF
YKL163W PIR3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall ->
cell wall MCM1, SMP1, SWI5
YOR273C TPO4 polyamine transport ->
transport spermine transporter activity, spermidine transporter activity ->
spermine transporter activity, spermidine transporter activity plasma membrane, vacuolar membrane ->
plasma membrane, cytoplasm ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
|YNL144C| NO SYMBOL RAP1
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane
YOR152C NO SYMBOL HIR2
|YAL046C| NO SYMBOL BAS1
YNL176C NO SYMBOL FKH2
YGR035C NO SYMBOL CIN5, MET4, SMP1, YAP6
|YGR050C| NO SYMBOL DAL82, FKH2, HSF1, INO4, MAL13, NRG1, RAP1, SKN7, SWI4
YNL008C ASI3 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YOR264W DSE3 SWI5
Main: transport (0.50) structural constituent of cell wall (0.25) cytoplasm (0.50) SMP1 FKH2 SWI5 BAS1 RAP1 SKN7 NRG1 (0.20)
Score: 0.17 0.00 0.33 0.133
P-value: 4.154E+00 (transport) 1.498E+00 (transporter activity) 1.092E+00 (plasma membrane) 4.292E-01 (SMP1)

m_g-proteins_orfnum2SD_n11(1) AND m_other_nutritional-response_activities_orfnum2SD_n10(1) AND mRRPE(1) => SimExpr(YJR122W) OR SimExpr(other) : 5 2

EXPR: (0.205) m_g-proteins_orfnum2SD_n11 (P < 0.000) mRRPE (P < 0.000) m_other_nutritional-response_activities_orfnum2SD_n10 (P < 0.001)

ORF SYMBOL P F C TF
YLR328W NMA1 nicotinamide adenine dinucleotide metabolism ->
nicotinamide adenine dinucleotide metabolism nicotinamide-nucleotide adenylyltransferase activity ->
nucleotidyltransferase activity CIN5, MSN1, ROX1
|YOR224C| RPB8 transcription from Pol III promoter, transcription from Pol I promoter, transcription from Pol II promoter ->
transcription from Pol III promoter, transcription from Pol I promoter, transcription from Pol II promoter DNA-directed RNA polymerase activity ->
nucleotidyltransferase activity DNA-directed RNA polymerase II\, core complex, DNA-directed RNA polymerase III complex, DNA-directed RNA polymerase I complex ->
DNA-directed RNA polymerase II\, core complex, DNA-directed RNA polymerase III complex, DNA-directed RNA polymerase I complex ABF1
|YOL121C| RPS19A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosolic small ribosomal subunit (sensu Eukarya) AZF1, FHL1, GCR1, GCR2, HAL9, MET31, MOT3, PDR1, RAP1, ROX1, RPH1, SMP1, YAP6, ZAP1
YJR122W CAF17 YAP1
YDR100W TVP15 RAP1
YPR194C OPT2 oligopeptide transport ->
oligopeptide transport oligopeptide transporter activity ->
oligopeptide transporter activity FKH2, GRF10(Pho2), NDD1, SWI4
YGL098W USE1 RCS1
Main: transcription from Pol I promoter (0.25) nucleotidyltransferase activity (0.50) DNA-directed RNA polymerase II\, core complex (0.50) RAP1 ROX1 (0.29)
Score: 0.00 0.17 0.00 0.095
P-value: 3.852E+00 (metabolism) 3.840E-02 (nucleotidyltransferase activity) 4.000E+00 (intracellular) 2.370E-01 (ROX1)

m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) AND REB1(1) => SimExpr(YKR011C) OR SimExpr(other) : 7 3

EXPR: (0.235) REB1 (P < 0.037) m_allantoin_and_allantoate_transporters_orfnum2SD_n13 (P < 0.003)

ORF SYMBOL P F C TF
|YNL197C| WHI3 regulation of cell size ->
cell organization and biogenesis RNA binding ->
RNA binding REB1
YLR309C IMH1 vesicle-mediated transport ->
transport cytosol ->
cytoplasm DOT6
YKR011C NO SYMBOL SWI4, SWI6
YMR002W NO SYMBOL NDD1, REB1, SWI6
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
|YPL231W| FAS2 fatty acid biosynthesis, protein-cofactor linkage ->
protein metabolism, biosynthesis, lipid metabolism, organic acid metabolism 3-oxoacyl-[acyl-carrier protein] synthase activity, 3-oxoacyl-[acyl-carrier protein] reductase activity, holo-[acyl-carrier protein] synthase activity ->
transferase activity\, transferring groups other than amino-acyl groups, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor, phosphotransferase activity\, for other substituted phosphate groups fatty-acid synthase complex ->
cytoplasm INO2, INO4
YGL248W PDE1 cAMP-mediated signaling ->
signal transduction cAMP-specific phosphodiesterase activity ->
phosphoric ester hydrolase activity MSN2, MSN4
YKR028W SAP190 G1/S transition of mitotic cell cycle ->
cell proliferation protein serine/threonine phosphatase activity ->
phosphoric ester hydrolase activity cytoplasm ->
cytoplasm PHO4, SMP1
YPL260W NO SYMBOL SUM1
|YNL091W| NST1 salinity response ->
response to abiotic stimulus FKH1, REB1
Main: cell organization and biogenesis (0.29) phosphoric ester hydrolase activity (0.40) cytoplasm (1.00) REB1 (0.40)
Score: 0.14 0.10 1.00 0.156
P-value: 5.749E+00 (transport) 2.618E-01 (phosphoric ester hydrolase activity) 1.874E+00 (cytosol) 4.931E-03 (REB1)

m_g-proteins_orfnum2SD_n13(1) AND REB1(1) => SimExpr(YKR011C) OR SimExpr(other) : 7 2

PAC(1) AND m_other_energy_generation_activities_orfnum2SD_n16(1) => SimExpr(YGR280C) OR SimExpr(other) : 6 1

EXPR: (0.213) PAC (P < 0.020) m_other_energy_generation_activities_orfnum2SD_n16 (P < 0.001)

ORF SYMBOL P F C TF
|YGR251W| NO SYMBOL MSN4, PHD1, SKN7
YIL096C NO SYMBOL GAT3, HAP2, MOT3, RTS2
YNL023C FAP1 transcription factor activity ->
transcription factor activity
YDR384C ATO3 transport, nitrogen utilization ->
transport, nitrogen utilization transporter activity ->
transporter activity membrane ->
membrane ABF1, FHL1, INO4
YNR046W NO SYMBOL ABF1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription RNA binding ->
RNA binding nucleolus ->
nucleolus
YDR017C KCS1 vacuole organization and biogenesis, response to stress ->
cytoplasm organization and biogenesis, response to stress inositol/phosphatidylinositol kinase activity ->
inositol/phosphatidylinositol kinase activity
Main: cytoplasm organization and biogenesis (0.67) RNA binding (0.25) membrane (0.50) ABF1 (0.50)
Score: 0.33 0.00 0.00 0.167
P-value: 3.004E+00 (cytoplasm organization and biogenesis) 1.380E+00 (nucleic acid binding) 3.000E+00 (cell) 5.871E-01 (HAP2)

m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YGR244C) OR SimExpr(other) : 6 2

EXPR: (0.225) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.000) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.002) m_anion_transporters_orfnum2SD_n15 (P < 0.000)

m_RRSE3(1) AND mRRPE(1) AND LYS14(1) => SimExpr(YML093W) OR SimExpr(other) : 5 2

EXPR: (0.219) mRRPE (P < 0.000) LYS14 (P < 0.001) m_RRSE3 (P < 0.002)

ORF SYMBOL P F C TF
YHR052W CIC1 protein catabolism ->
protein catabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleolus, cytosol, endoplasmic reticulum, nucleus HAP4, MATa1
YNL110C NOP15 ribosomal large subunit biogenesis ->
ribosome biogenesis nucleus, nucleolus ->
nucleus, nucleolus
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleolus, nuclear membrane RAP1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis, snRNA processing, RNA processing, transcription from Pol I promoter RNA binding ->
RNA binding nucleolus ->
nucleolus
|YJR070C| NO SYMBOL GAT3, YAP5
YML093W UTP14 processing of 20S pre-rRNA ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
|YOR355W| GDS1 aerobic respiration ->
aerobic respiration FHL1, GCR1, PHD1, RLM1
Main: ribosome biogenesis (0.60) RNA binding (0.67) nucleolus (1.00) RLM1 (0.25)
Score: 0.30 0.33 1.00 0.000
P-value: 3.855E-02 (ribosome biogenesis) 5.131E-01 (RNA binding) 1.249E-05 (nucleolus) 6.816E-01 (MATa1)

PAC(1) AND mRRPE(1) AND LYS14(1) => SimExpr(YML093W) OR SimExpr(other) : 6 2

EXPR: (0.210) mRRPE (P < 0.000) LYS14 (P < 0.000) PAC (P < 0.002)

ORF SYMBOL P F C TF
YHR052W CIC1 protein catabolism ->
macromolecule catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
YNL110C NOP15 ribosomal large subunit biogenesis ->
cytoplasm organization and biogenesis nucleus, nucleolus ->
nucleus
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleus, endomembrane system RAP1
|YMR259C| NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription RNA binding ->
RNA binding nucleolus ->
nucleus
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation with cellular fusion, sporulation (sensu Fungi), cytoplasm organization and biogenesis, intracellular transport, protein metabolism, protein transport GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm ->
cytoplasm PHO4
|YJR070C| NO SYMBOL GAT3, YAP5
YML093W UTP14 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
Main: cytoplasm organization and biogenesis (0.80) RNA binding (0.50) nucleus (0.83) GCR2 (0.20)
Score: 0.70 0.17 0.73 0.000
P-value: 3.295E-03 (ribosome biogenesis) 6.494E-01 (RNA binding) 3.761E-05 (nucleolus) 9.470E-01 (MATa1)

SFF'(1) AND m_amino-acid_biosynthesis_orfnum2SD_n9(1) AND SCB(1) => SimExpr(YDL198C) OR SimExpr(other) : 6 2

EXPR: (0.220) SFF' (P < 0.000) SCB (P < 0.000) m_amino-acid_biosynthesis_orfnum2SD_n9 (P < 0.018)

ORF SYMBOL P F C TF
|YKL090W| CUE2
YMR272C SCS7 fatty acid metabolism ->
lipid metabolism, organic acid metabolism oxidoreductase activity ->
oxidoreductase activity endoplasmic reticulum ->
cytoplasm IXR1, SUM1
YDR472W TRS31 ER to Golgi transport ->
transport, vesicle-mediated transport TRAPP ->
cytoplasm GCR1, IXR1, RFX1
YJR016C ILV3 branched chain family amino acid biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis dihydroxy-acid dehydratase activity ->
dihydroxy-acid dehydratase activity mitochondrion ->
cytoplasm
YMR233W NO SYMBOL
|YKL042W| SPC42 microtubule nucleation, spindle pole body duplication (sensu Saccharomyces) ->
cell organization and biogenesis, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton intermediate layer of spindle pole body, central plaque of spindle pole body ->
cytoplasm
YDL198C YHM1 transport, mitochondrial genome maintenance ->
transport, cell organization and biogenesis transporter activity ->
transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane GCN4
YGR055W MUP1 sulfur amino acid transport ->
transport transporter activity ->
transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane DAL81, INO4, MET4, STP1
Main: transport (0.50) transporter activity (0.40) cytoplasm (0.83) IXR1 (0.50)
Score: 0.33 0.10 0.67 0.167
P-value: 9.764E-01 (organic acid metabolism) 9.525E-01 (transporter activity) 1.995E+00 (mitochondrion) 9.702E-02 (IXR1)

m_lipid_and_fatty-acid_transport_orfnum2SD_n11(1) AND m_phosphate_transport_orfnum2SD_n13(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YDL198C) : 5

EXPR: (0.142) m_lipid_and_fatty-acid_transport_orfnum2SD_n11 (P < 0.000) m_phosphate_transport_orfnum2SD_n13 (P < 0.001) m_phosphate_transport_orfnum2SD_n18 (P < 0.000)

RAP1(1) AND SWI5(1) => SimExpr(YLR344W) OR SimExpr(other) : 16 7

EXPR: (0.218) SWI5 (P < 0.000) RAP1 (P < 0.172)

RAP1(1) AND m_nitrogen_and_sulphur_transport_orfnum2SD_n9(1) => SimExpr(YLR344W) OR SimExpr(other) : 7 2

RAP1(1) AND SFF(1) => SimExpr(YLR344W) OR SimExpr(other) : 27 13

EXPR: (0.229) SFF (P < 0.000) RAP1 (P < 0.331)

RAP1(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) => SimExpr(YLR344W) OR SimExpr(other) : 6 1

RAP1(1) AND CSRE(1) => SimExpr(YLR344W) OR SimExpr(other) : 12 2

RAP1(1) AND MCM1'(1) => SimExpr(YLR344W) OR SimExpr(other) : 19 1

RAP1(1) AND m_g-proteins_orfnum2SD_n12(1) => SimExpr(YLR344W) OR SimExpr(other) : 15 6

EXPR: (0.213) m_g-proteins_orfnum2SD_n12 (P < 0.000) RAP1 (P < 0.103)

RAP1(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YLR344W) OR SimExpr(other) : 5 2

EXPR: (0.202) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.002) RAP1 (P < 0.149)

ORF SYMBOL P F C TF
YMR193W MRPL24 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
mitochondrion, ribosome ARO80, HAP4, HAP5, LEU3, MET31, RTG1, RTG3, STE12, STP1, UGA3
YJR145C RPS4A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm ->
cytosol, cytoplasm, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YNL069C RPL16B protein biosynthesis ->
protein biosynthesis RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YGL076C RPL7A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
YLR344W RPL26A protein biosynthesis ->
protein biosynthesis RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, RAP1
|YGL196W| NO SYMBOL
|YJL217W| NO SYMBOL CIN5, MAC1, PHD1, SWI5, YAP6
Main: protein biosynthesis (1.00) structural constituent of ribosome (1.00) ribosome (1.00) RAP1 FHL1 (0.60)
Score: 1.00 1.00 1.00 0.400
P-value: 2.810E-03 (protein biosynthesis) 1.141E-04 (structural constituent of ribosome) 5.125E-04 (large ribosomal subunit) 2.095E-02 (FHL1)

RAP1(1) AND m_LFTE17(1) => SimExpr(YLR344W) : 7

RAP1(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) => SimExpr(YLR344W) : 7

RAP1(1) AND MCM1'(1) AND ALPHA1'(1) => SimExpr(YLR344W) : 7

EXPR: (0.164) RAP1 (P < 0.007) ALPHA1' (P < 0.000) MCM1' (P < 0.000)

RAP1(1) AND MCM1'(1) AND CSRE(1) => SimExpr(YLR344W) : 9

EXPR: (0.161) RAP1 (P < 0.003) CSRE (P < 0.000) MCM1' (P < 0.000)

MCB(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n8(1) => SimExpr(YKL042W) OR SimExpr(other) : 6 1

SFF(1) AND MCB(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n8(1) => SimExpr(YKL042W) : 5

EXPR: (0.134) SFF (P < 0.000) m_deoxyribonucleotide_metabolism_orfnum2SD_n8 (P < 0.000) MCB (P < 0.008)

ORF SYMBOL P F C TF
YLR212C TUB4 microtubule nucleation, mitotic spindle assembly (sensu Saccharomyces) ->
cell organization and biogenesis, cell proliferation, cell cycle structural constituent of cytoskeleton ->
structural constituent of cytoskeleton inner plaque of spindle pole body, outer plaque of spindle pole body ->
cytoplasm
YIL026C IRR1 mitotic sister chromatid cohesion, colony morphology, germination (sensu Saccharomyces), cytogamy ->
cell organization and biogenesis, sporulation, plasma membrane fusion, sporulation (sensu Fungi), cell proliferation, conjugation, sexual reproduction protein binding ->
protein binding nuclear cohesin complex ->
chromosome, nucleus ABF1, MAL33, MBP1, SWI6
YFR027W ECO1 sister chromatid cohesion, DNA replication, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation acetyltransferase activity ->
acetyltransferase activity nuclear chromatin ->
chromosome, nucleus
YNL039W BDP1 transcription initiation from Pol III promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase III transcription factor activity ->
RNA polymerase III transcription factor activity transcription factor TFIIIB complex ->
nucleus
YKL042W SPC42 microtubule nucleation, spindle pole body duplication (sensu Saccharomyces) ->
cell organization and biogenesis, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton intermediate layer of spindle pole body, central plaque of spindle pole body ->
cytoplasm
Main: cell proliferation (0.80) structural constituent of cytoskeleton (0.40) nucleus (0.60) (0.00)
Score: 0.70 0.10 0.40 0.000
P-value: 1.488E-03 (DNA replication and chromosome cycle) 1.047E-02 (structural constituent of cytoskeleton) 4.871E-02 (spindle pole body) 1.000E+00

m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YNR001C) OR SimExpr(other) : 7 3

m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) AND m_glycolysis_and_gluconeogenesis_orfnum2SD_n14(1) => SimExpr(YNR001C) OR SimExpr(other) : 6 2

EXPR: (0.213) m_tricarboxylic-acid_pathway_orfnum2SD_n3 (P < 0.016) m_glycolysis_and_gluconeogenesis_orfnum2SD_n14 (P < 0.010)

ORF SYMBOL P F C TF
YIL117C PRM5 conjugation with cellular fusion ->
conjugation, sexual reproduction integral to membrane ->
integral to membrane
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane
|YOR161C| NO SYMBOL FHL1, PHD1, RAP1
YGR086C PIL1 ASH1, SWI5
|YGR067C| NO SYMBOL ABF1, ASH1, RGM1
YPL078C ATP4 ATP synthesis coupled proton transport ->
transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane REB1, ZAP1
YMR315W NO SYMBOL
YNR001C CIT1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis citrate (SI)-synthase activity ->
citrate (SI)-synthase activity mitochondrial matrix, mitochondrion ->
cytoplasm RGM1
Main: transport (0.50) structural molecule activity (0.33) cytoplasm (0.50) ASH1 RGM1 (0.40)
Score: 0.17 0.00 0.33 0.200
P-value: 3.064E+00 (transport) 2.919E+00 (enzyme activity) 5.277E-01 (integral to membrane) 2.272E-02 (ASH1)

ALPHA1'(1) AND m_anion_transporters_orfnum2SD_n15(1) AND m_lipid_transporters_orfnum2SD_n8(1) => SimExpr(YPL143W) OR SimExpr(other) : 5 2

EXPR: (0.208) m_anion_transporters_orfnum2SD_n15 (P < 0.004) ALPHA1' (P < 0.000) m_lipid_transporters_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
|YMR139W| RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MAL33, YJL206C
YDR476C NO SYMBOL MTH1
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YDR134C NO SYMBOL ASH1, NRG1, SOK2, SWI4
YPL143W RPL33A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MET4, NDD1, PDR1, RAP1, RME1
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity CRZ1
|YKR013W| PRY2 SWI4, SWI6
Main: biosynthesis (0.75) structural constituent of ribosome (0.25) cytoplasm (1.00) SWI4 MET4 (0.29)
Score: 0.67 0.00 1.00 0.095
P-value: 1.955E-01 (amino acid biosynthesis) 2.414E+00 (enzyme activity) 4.869E+00 (cytoplasm) 7.371E-02 (MET4)

m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) AND m_anion_transporters_orfnum2SD_n4(1) => SimExpr(YPL143W) OR SimExpr(other) : 6 2

MCM1'(1) AND m_ion_transporters_orfnum2SD_n7(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YOR155C) OR SimExpr(other) : 6 2

EXPR: (0.221) m_ion_transporters_orfnum2SD_n7 (P < 0.002) m_amino-acid_transport_orfnum2SD_n18 (P < 0.007) MCM1' (P < 0.001)

ORF SYMBOL P F C TF
YKL189W HYM1 cytokinesis\, completion of separation, regulation of cell shape ->
cell proliferation, cell organization and biogenesis transcriptional repressor activity ->
transcriptional repressor activity intracellular ->
intracellular DIG1, STE12
YNL069C RPL16B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
intracellular FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YOR155C ISN1
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
intracellular, integral to membrane, inner membrane HAP4
|YDR044W| HEM13 heme biosynthesis ->
pigment metabolism, coenzymes and prosthetic group biosynthesis, coenzymes and prosthetic group metabolism, biosynthesis, heterocycle metabolism coproporphyrinogen oxidase activity ->
coproporphyrinogen oxidase activity mitochondrial inner membrane ->
intracellular, inner membrane
YGR121C MEP1 ammonium transport ->
transport ammonium transporter activity ->
ammonium transporter activity plasma membrane ->
plasma membrane CIN5
|YIL030C| SSM4 mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity nuclear membrane ->
intracellular, endomembrane system ABF1
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
ARF small monomeric GTPase activity Golgi vesicle, cytosol ->
intracellular MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: transport (0.43) ammonium transporter activity (0.17) intracellular (0.86) ABF1 (0.17)
Score: 0.19 0.00 0.71 0.000
P-value: 1.394E-01 (cation transport) 3.060E+00 (binding) 4.184E-01 (mitochondrial inner membrane) 1.000E+00

m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YOR155C) : 5

EXPR: (0.161) m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5 (P < 0.001) m_amino-acid_transport_orfnum2SD_n18 (P < 0.001)

ORF SYMBOL P F C TF
YKL189W HYM1 cytokinesis\, completion of separation, regulation of cell shape ->
cytokinesis\, completion of separation, regulation of cell shape transcriptional repressor activity ->
transcriptional repressor activity intracellular ->
intracellular DIG1, STE12
YOR155C ISN1
YAR044W OSH1 steroid biosynthesis ->
steroid biosynthesis oxysterol binding, phosphatidylinositol binding ->
oxysterol binding, phosphatidylinositol binding Golgi trans cisterna, early endosome, endoplasmic reticulum ->
intracellular
YGR237C NO SYMBOL
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
ER to Golgi transport, intra-Golgi transport ARF small monomeric GTPase activity ->
ARF small monomeric GTPase activity Golgi vesicle, cytosol ->
intracellular MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: cytokinesis\, completion of separation (0.33) ARF small monomeric GTPase activity (0.33) intracellular (1.00) SOK2 (0.50)
Score: 0.00 0.00 1.00 0.000
P-value: 4.224E+00 (cell growth and/or maintenance) 1.478E+00 (binding) 5.398E-02 (Golgi apparatus) 3.879E-01 (RGT1)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_RRSE3(1) AND m_g-proteins_orfnum2SD_n12(1) AND PAC(1) => SimExpr(YNR053C) OR SimExpr(other) : 11 2

EXPR: (0.212) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_RRSE3 (P < 0.000) PAC (P < 0.000)

ORF SYMBOL P F C TF
|YPR149W| NCE102 protein secretion ->
protein secretion integral to membrane, endoplasmic reticulum, cytoplasm ->
integral to membrane, cytoplasm CIN5, FKH2, GRF10(Pho2), HSF1, NDD1, PUT3, RAP1, SKN7, SWI4, YAP6
YHR146W CRP1 DNA binding ->
DNA binding nucleus ->
nucleus IXR1
YNL141W AAH1 adenine catabolism ->
aromatic compound metabolism, catabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism adenine deaminase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds YFL044C
YGL078C DBP3 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
YDR496C PUF6 RFX1
|YPR010C| RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YNL110C NOP15 ribosomal large subunit biogenesis ->
cell organization and biogenesis nucleus, nucleolus ->
nucleus
YDR017C KCS1 vacuole organization and biogenesis, response to stress ->
cell organization and biogenesis, response to stress inositol/phosphatidylinositol kinase activity ->
transferase activity\, transferring phosphorus-containing groups
YGL255W ZRT1 high-affinity zinc ion transport ->
transport high affinity zinc uptake transporter activity ->
cation transporter activity, metal ion transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane GRF10(Pho2), ZAP1
YNR053C NOG2 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleus, nucleolus, nucleoplasm ->
nucleus, nucleoplasm ABF1, AZF1
YGR159C NSR1 ribosomal small subunit assembly and maintenance, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism single-stranded DNA binding, RNA binding ->
DNA binding, RNA binding nucleolus, nucleus ->
nucleus
YNL112W DBP2 RNA helicase activity ->
RNA binding bud neck ->
site of polarized growth (sensu Fungi)
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.56) RNA binding (0.33) nucleus (0.67) GRF10(Pho2) (0.25)
Score: 0.42 0.17 0.44 0.036
P-value: 7.731E-02 (ribosomal subunit assembly) 1.423E-01 (RNA helicase activity) 8.409E-04 (nucleolus) 5.453E-01 (GRF10(Pho2))

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND SFF(1) AND m_RRSE3(1) AND m_g-proteins_orfnum2SD_n12(1) AND mRRPE(1) => SimExpr(YNR053C) OR SimExpr(other) : 7 2

EXPR: (0.209) SFF (P < 0.000) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) mRRPE (P < 0.001) m_g-proteins_orfnum2SD_n12 (P < 0.001) m_RRSE3 (P < 0.000)

ORF SYMBOL P F C TF
YGL078C DBP3 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA helicase activity, ATP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides nucleolus ->
nucleus
YDR496C PUF6 RFX1
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YDR341C NO SYMBOL GCN4, ZMS1
|YPL060W| LPE10 mitochondrial magnesium ion transport ->
transport magnesium ion transporter activity ->
magnesium ion transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane HIR2
YKL029C MAE1 pyruvate metabolism, amino acid metabolism ->
amine metabolism, organic acid metabolism, amino acid and derivative metabolism malate dehydrogenase (oxaloacetate decarboxylating) activity ->
malic enzyme activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrion ->
cytoplasm ABF1, CIN5
YKL057C NUP120 mRNA-nucleus export, rRNA-nucleus export, snRNA-nucleus export, tRNA-nucleus export, NLS-bearing substrate-nucleus import, snRNP protein-nucleus import, mRNA-binding (hnRNP) protein-nucleus import, ribosomal protein-nucleus import, protein-nucleus export, nuclear pore organization and biogenesis ->
intracellular transport, intracellular protein transport, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transport structural molecule activity ->
structural molecule activity nuclear pore ->
nucleus, integral to membrane, endomembrane system GCR1
YNR053C NOG2 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism GTPase activity ->
GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides nucleus, nucleolus, nucleoplasm ->
nucleus, nucleoplasm ABF1, AZF1
|YOR355W| GDS1 aerobic respiration ->
energy pathways FHL1, GCR1, PHD1, RLM1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.50) hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides (0.40) nucleus (0.60) ABF1 GCR1 (0.25)
Score: 0.27 0.10 0.40 0.071
P-value: 1.363E+00 (RNA processing) 1.210E+00 (hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides) 4.584E-01 (nucleolus) 7.161E-02 (GCR1)

ABF1(1) AND m_amino-acid_transport_orfnum2SD_n13(1) => SimExpr(YGR253C) OR SimExpr(other) : 5 2

EXPR: (0.223) ABF1 (P < 0.002) m_amino-acid_transport_orfnum2SD_n13 (P < 0.013)

ORF SYMBOL P F C TF
YGR253C PUP2 ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) ->
catabolism, response to stress, sporulation, protein metabolism endopeptidase activity ->
peptidase activity proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus ABF1, HIR2, PHO4
|YDR091C| RLI1 ATP-binding cassette (ABC) transporter activity ->
purine nucleotide binding, primary active transporter activity, hydrolase activity\, acting on acid anhydrides
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds cytosol ->
cytoplasm GCN4
YNL138W SRV2 cytoskeleton organization and biogenesis, RAS protein signal transduction ->
cell organization and biogenesis, signal transduction cytoskeletal protein binding, adenylate cyclase binding ->
cytoskeletal protein binding, enzyme binding actin cortical patch (sensu Saccharomyces) ->
cell cortex, cytoplasm ABF1
YMR297W PRC1 vacuolar protein catabolism ->
catabolism, protein metabolism carboxypeptidase C activity ->
peptidase activity cytoplasm, endoplasmic reticulum ->
cytoplasm ABF1
|YNL201C| PSY2
YGL225W VRG4 nucleotide-sugar transport, N-linked glycosylation, lipid glycosylation ->
transport, biosynthesis, lipid metabolism, protein metabolism nucleotide-sugar transporter activity ->
nucleotide-sugar transporter activity Golgi apparatus ->
cytoplasm
Main: protein metabolism (0.60) peptidase activity (0.33) cytoplasm (1.00) ABF1 (0.75)
Score: 0.50 0.07 1.00 0.500
P-value: 1.660E-01 (catabolism) 1.215E-01 (peptidase activity) 6.089E-01 (endoplasmic reticulum) 3.700E-02 (ABF1)

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND m_cell_rescue_defense_cell_death_and_ageing_orfnum2SD_n20(1) => SimExpr(YLR205C) : 5

EXPR: (0.162) m_cell_rescue_defense_cell_death_and_ageing_orfnum2SD_n20 (P < 0.005) m_metabolism_of_energy_reserves_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YKL163W PIR3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall ->
cell wall MCM1, SMP1, SWI5
YGR088W CTT1 response to stress ->
response to stress catalase activity ->
oxidoreductase activity\, acting on peroxide as acceptor cytoplasm ->
cytoplasm
YLR205C HMX1 iron ion homeostasis ->
cell homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
oxidoreductase activity\, acting on peroxide as acceptor, heme binding, oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen membrane ->
membrane MAL13, PHO4, SKN7
YOR096W RPS7A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, FKH2, RAP1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides plasma membrane ->
membrane ACE2, SKN7
Main: cell organization and biogenesis (0.40) oxidoreductase activity\, acting on peroxide as acceptor (0.40) membrane (0.40) SKN7 (0.50)
Score: 0.10 0.10 0.20 0.167
P-value: 2.630E+00 (cell organization and biogenesis) 1.219E-03 (oxidoreductase activity\, acting on peroxide as acceptor) 1.942E+00 (membrane) 1.284E-01 (SKN7)

SFF(1) AND m_nutritional_response_pathway_orfnum2SD_n8(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YFR033C) OR SimExpr(other) : 6 2

EXPR: (0.214) SFF (P < 0.000) m_cell_death_orfnum2SD_n8 (P < 0.011) m_nutritional_response_pathway_orfnum2SD_n8 (P < 0.002)

m_other_cation_transporters_orfnum2SD_n8(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YFR033C) OR SimExpr(other) : 5 2

EXPR: (0.223) m_anion_transporters_orfnum2SD_n15 (P < 0.009) m_other_cation_transporters_orfnum2SD_n8 (P < 0.033)

ORF SYMBOL P F C TF
YOL019W NO SYMBOL SWI4
YPR036W VMA13 vacuolar acidification ->
cell homeostasis, cell organization and biogenesis, transport hydrogen-exporting ATPase activity ->
ATP binding, hydrogen ion transporter activity, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole
YOL012C HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
|YPL230W| NO SYMBOL NRG1, SKN7
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
oxidoreductase activity\, acting on diphenols and related substances as donors\, cytochrome as acceptor, primary active transporter activity, hydrogen ion transporter activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YNL183C NPR1 regulation of nitrogen utilization ->
nitrogen metabolism kinase activity ->
kinase activity cytoplasm ->
cytoplasm ABF1
|YGR050C| NO SYMBOL DAL82, FKH2, HSF1, INO4, MAL13, NRG1, RAP1, SKN7, SWI4
Main: cell organization and biogenesis (0.50) hydrogen ion transporter activity (0.50) cytoplasm (0.75) SWI4 (0.50)
Score: 0.17 0.17 0.50 0.267
P-value: 4.450E+00 (cell organization and biogenesis) 2.381E-02 (hydrogen ion transporter activity) 3.016E+00 (membrane) 2.852E-02 (SWI4)

m_regulation_of_nucleotide_metabolism_orfnum2SD_n5(1) AND CSRE(1) => SimExpr(YFR033C) OR SimExpr(other) : 8 3

m_MERE4(1) AND HAP234(1) => SimExpr(YFR033C) OR SimExpr(other) : 7 1

EXPR: (0.171) HAP234 (P < 0.006) m_MERE4 (P < 0.000)

ORF SYMBOL P F C TF
YNL052W COX5A aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors\, oxygen as acceptor, primary active transporter activity, hydrogen ion transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane HAP4
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
oxidoreductase activity\, acting on diphenols and related substances as donors\, cytochrome as acceptor, primary active transporter activity, hydrogen ion transporter activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
|YJL079C| PRY1 nuclear membrane, endoplasmic reticulum ->
nucleus, cytoplasm, endomembrane system NDD1, PHD1, RAP1
YPL078C ATP4 ATP synthesis coupled proton transport ->
transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane REB1, ZAP1
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides Golgi vesicle, cytosol ->
cytoplasm, Golgi apparatus MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: energy pathways (0.57) primary active transporter activity (0.33) cytoplasm (1.00) HAP4 (0.38)
Score: 0.43 0.07 1.00 0.143
P-value: 7.829E-03 (glutamate biosynthesis) 3.156E-02 (hydrogen ion transporter activity) 1.944E-03 (mitochondrion) 2.081E-03 (HAP4)

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_MERE4(1) => SimExpr(YFR033C) OR SimExpr(other) : 8 3

EXPR: (0.225) m_regulation_of_amino-acid_metabolism_orfnum2SD_n15 (P < 0.007) m_MERE4 (P < 0.001)

ORF SYMBOL P F C TF
|YHR100C| NO SYMBOL
YOR032C HMS1 pseudohyphal growth ->
cellular morphogenesis transcription factor activity ->
transcription factor activity CUP9, HAL9, INO4, NRG1, RAP1, SFP1, YAP6
YDR511W ACN9 carbon utilization by utilization of organic compounds, gluconeogenesis ->
carbon utilization by utilization of organic compounds, alcohol biosynthesis, monosaccharide metabolism, carbohydrate metabolism, carbohydrate biosynthesis, energy derivation by oxidation of organic compounds mitochondrial intermembrane space ->
cytoplasm MBP1, STB1
YNL208W NO SYMBOL INO2
YLR205C HMX1 iron ion homeostasis ->
cell ion homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy derivation by oxidation of organic compounds, electron transport, phosphate metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, membrane HAP4, MBP1
|YGR067C| NO SYMBOL ABF1, ASH1, RGM1
YJR009C TDH2 gluconeogenesis, glycolysis ->
alcohol biosynthesis, alcohol catabolism, carbohydrate metabolism, monosaccharide metabolism, carbohydrate biosynthesis, carbohydrate catabolism, energy derivation by oxidation of organic compounds glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity cytosol, lipid particle, cell wall, cytoplasm ->
cytoplasm, cell wall CBF1, GCR1, GCR2
YPL078C ATP4 ATP synthesis coupled proton transport ->
hydrogen transport, ion transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, membrane REB1, ZAP1
|YPR151C| SUE1 MAL33, MTH1, NDD1, SKN7
YOR299W BUD7 bud site selection ->
cytokinesis, cytoplasm organization and biogenesis HSF1, MTH1
Main: energy derivation by oxidation of organic compounds (0.43) ubiquinol-cytochrome c reductase activity (0.20) cytoplasm (0.80) MTH1 SKN7 MBP1 (0.20)
Score: 0.14 0.00 0.80 0.067
P-value: 1.088E-01 (gluconeogenesis) 2.333E-01 (oxidoreductase activity) 6.918E-01 (mitochondrial inner membrane) 5.503E-01 (MTH1)

m_nitrogen_and_sulphur_metabolism_orfnum2SD_n22(1) AND m_nutritional_response_pathway_orfnum2SD_n7(1) => SimExpr(YFR033C) OR SimExpr(other) : 5 2

EXPR: (0.213) m_nutritional_response_pathway_orfnum2SD_n7 (P < 0.000) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n22 (P < 0.016)

ORF SYMBOL P F C TF
|YOR037W| CYC2 mitochondrial intermembrane space protein import, mitochondrial membrane organization and biogenesis ->
cell organization and biogenesis, protein metabolism, transport mitochondrion ->
cytoplasm
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YDR276C PMP3 cation transport ->
transport plasma membrane ->
plasma membrane GAT1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
YMR086W NO SYMBOL FKH1
|YKL187C| NO SYMBOL
Main: cell organization and biogenesis (0.40) ubiquinol-cytochrome c reductase activity (0.33) cytoplasm (0.60) ACE2 (0.20)
Score: 0.20 0.00 0.40 0.000
P-value: 3.490E+00 (transport) 1.611E+00 (hydrolase activity) 5.633E-01 (plasma membrane) 3.507E-01 (GAT1)

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YFR033C) : 6

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YPL203W) OR SimExpr(other) : 5 1

SFF'(1) AND m_RPE8(1) AND CSRE(1) => SimExpr(YGR209C) OR SimExpr(other) : 7 2

EXPR: (0.191) SFF' (P < 0.000) m_RPE8 (P < 0.001) CSRE (P < 0.000)

mRRPE(1) AND m_amino-acid_transport_orfnum2SD_n18(1) AND SCB(1) => SimExpr(YKR059W) OR SimExpr(other) : 6 2

EXPR: (0.197) mRRPE (P < 0.001) m_amino-acid_transport_orfnum2SD_n18 (P < 0.002) SCB (P < 0.001)

ORF SYMBOL P F C TF
|YJL080C| SCP160 chromosome segregation, mRNA localization\, intracellular ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nuclear envelope-endoplasmic reticulum network, polysome, endoplasmic reticulum membrane ->
endomembrane system, cytoplasm, ribonucleoprotein complex ACE2, MBP1, NDD1, SWI5
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YOR285W NO SYMBOL HIR1, STP1
|YGR280C| PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YDL229W SSB1 protein biosynthesis ->
biosynthesis, protein metabolism chaperone activity, ATPase activity ->
chaperone activity, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides polysome, soluble fraction ->
cytoplasm, soluble fraction, ribonucleoprotein complex ABF1, RFX1
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transferase activity\, transferring aldehyde or ketonic groups cytoplasm ->
cytoplasm REB1
YKR059W TIF1 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FKH1, FKH2
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
Main: biosynthesis (0.57) RNA binding (0.29) cytoplasm (0.83) ABF1 (0.33)
Score: 0.43 0.10 0.67 0.067
P-value: 6.150E-01 (protein biosynthesis) 8.887E-02 (translation factor activity\, nucleic acid binding) 2.464E-03 (polysome) 1.000E+00

m_metabolism_of_energy_reserves_orfnum2SD_n29(1) AND mRRPE(1) AND SCB(1) => SimExpr(YKR059W) OR SimExpr(other) : 6 1

EXPR: (0.208) mRRPE (P < 0.008) SCB (P < 0.000) m_metabolism_of_energy_reserves_orfnum2SD_n29 (P < 0.000)

ORF SYMBOL P F C TF
|YJL109C| UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
snoRNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YMR038C LYS7 intracellular copper ion transport ->
transport superoxide dismutase copper chaperone activity ->
superoxide dismutase copper chaperone activity cytosol ->
cytoplasm CAD1, CIN5, YAP1
YDR062W LCB2 sphingolipid biosynthesis ->
biosynthesis, lipid metabolism serine C-palmitoyltransferase activity ->
serine C-palmitoyltransferase activity membrane fraction, microsome, serine C-palmitoyltransferase complex ->
membrane fraction, endoplasmic reticulum, endomembrane system
YKR071C DRE2 CAD1, HSF1, YAP1, YAP3
YKR059W TIF1 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FKH1, FKH2
YLR297W NO SYMBOL
YPR041W TIF5 regulation of translational initiation, mature ribosome assembly ->
cell organization and biogenesis, biosynthesis, protein metabolism GTPase activator activity, translation initiation factor activity ->
GTPase activator activity, translation initiation factor activity cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
Main: biosynthesis (0.60) translation initiation factor activity (0.40) cytoplasm (0.60) CAD1 YAP1 (0.67)
Score: 0.40 0.10 0.50 0.333
P-value: 3.601E-02 (translational initiation) 2.247E-02 (translation initiation factor activity) 2.400E-01 (ribonucleoprotein complex) 1.802E-02 (CAD1)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9(1) => SimExpr(YOR299W) OR SimExpr(other) : 9 4

EXPR: (0.225) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.003) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9 (P < 0.023)

ORF SYMBOL P F C TF
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
|YML054C| CYB2 electron transport ->
electron transport L-lactate dehydrogenase (cytochrome) activity ->
oxidoreductase activity\, acting on CH-OH group of donors mitochondrial intermembrane space ->
cytoplasm
|YMR181C| NO SYMBOL
YOL087C NO SYMBOL DAL82
|YNL068C| FKH2 G2-specific transcription in mitotic cell cycle, pseudohyphal growth, regulation of cell cycle ->
cell organization and biogenesis, cell proliferation, transcription transcription factor activity ->
DNA binding nucleus ->
nucleus FHL1, RAP1
YNL208W NO SYMBOL INO2
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups
YNL183C NPR1 regulation of nitrogen utilization ->
nitrogen metabolism kinase activity ->
kinase activity cytoplasm ->
cytoplasm ABF1
|YMR199W| CLN1 regulation of CDK activity ->
cell proliferation cyclin-dependent protein kinase\, regulator activity ->
transferase activity\, transferring phosphorus-containing groups, protein kinase regulator activity nucleus, cytoplasm ->
nucleus, cytoplasm FKH2, MBP1, NDD1, SKN7, STE12, SWI4, SWI6
YDR427W RPN9 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
peptidase activity proteasome regulatory particle (sensu Eukarya), proteasome regulatory particle\, lid subcomplex (sensu Eukarya) ->
cytoplasm, nucleus ARG81, IXR1
YIL009W FAA3 N-terminal protein myristoylation, lipid metabolism ->
biosynthesis, lipid metabolism, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
ligase activity\, forming carbon-sulfur bonds MAL13, SKN7, SWI5, YAP6
YDR100W TVP15 RAP1
YOR299W BUD7 bud site selection ->
cell proliferation, cell organization and biogenesis HSF1, MTH1
Main: cell proliferation (0.33) oxidoreductase activity\, acting on CH-OH group of donors (0.25) cytoplasm (0.83) SKN7 (0.30)
Score: 0.22 0.07 0.80 0.089
P-value: 6.780E-01 (glucose metabolism) 3.604E-01 (oxidoreductase activity\, acting on CH-OH group of donors) 5.346E+00 (nucleus) 2.860E-01 (SKN7)

m_MERE4(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YOR299W) OR SimExpr(other) : 9 3

EXPR: (0.222) m_peroxisomal_transport_orfnum2SD_n22 (P < 0.000) m_MERE4 (P < 0.002)

ORF SYMBOL P F C TF
YHR213W NO SYMBOL PHD1
|YOR009W| TIR4 cell wall (sensu Fungi) ->
cell wall MTH1
YOR155C ISN1
YOR032C HMS1 pseudohyphal growth ->
cell organization and biogenesis transcription factor activity ->
transcription factor activity CUP9, HAL9, INO4, NRG1, RAP1, SFP1, YAP6
|YAR062W| NO SYMBOL
YHR083W NO SYMBOL DIG1, STE12
YNL208W NO SYMBOL INO2
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
|YLR185W| RPL37A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1, RGM1, YAP5
YOR299W BUD7 bud site selection ->
cell proliferation, cell organization and biogenesis HSF1, MTH1
YMR086W NO SYMBOL FKH1
Main: cell organization and biogenesis (0.60) ubiquinol-cytochrome c reductase activity (0.25) cytoplasm (0.50) MTH1 RAP1 (0.20)
Score: 0.30 0.00 0.17 0.044
P-value: 2.241E-01 (pseudohyphal growth) 3.707E+00 (binding) 4.804E+00 (membrane) 5.263E-01 (MTH1)

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YOR299W) OR SimExpr(other) : 5 1

MCM1'(1) AND m_MERE4(1) AND m_c-compound_and_carbohydrate_utilization_orfnum2SD_n9(1) => SimExpr(YOR299W) : 7

m_other_energy_generation_activities_orfnum2SD_n22(1) AND m_ion_transporters_orfnum2SD_n11(1) => SimExpr(YLR297W) OR SimExpr(other) : 5 2

EXPR: (0.213) m_ion_transporters_orfnum2SD_n11 (P < 0.002) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.000)

m_LFTE17(1) AND m_purine_and_pyrimidine_transporters_orfnum2SD_n10(1) => SimExpr(YPL078C) OR SimExpr(other) : 5 1

EXPR: (0.162) m_purine_and_pyrimidine_transporters_orfnum2SD_n10 (P < 0.000) m_LFTE17 (P < 0.000)

m_MERE4(1) AND HAP234(1) => SimExpr(YPL078C) OR SimExpr(other) : 7 1

m_glyoxylate_cycle_orfnum2SD_n8(1) AND HAP234(1) => SimExpr(YPL078C) OR SimExpr(other) : 5 2

EXPR: (0.200) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.000) HAP234 (P < 0.064)

ORF SYMBOL P F C TF
|YDR344C| NO SYMBOL MSS11
YML028W TSA1 response to oxidative stress, regulation of redox homeostasis ->
response to oxidative stress, cell redox homeostasis thioredoxin peroxidase activity ->
thioredoxin peroxidase activity cytoplasm ->
cytoplasm MBP1, NDD1, SKN7, YAP1
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine biosynthesis, carboxylic acid metabolism, amine metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy derivation by oxidation of organic compounds, electron transport, phosphate metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
|YML087C| NO SYMBOL
YPL078C ATP4 ATP synthesis coupled proton transport ->
hydrogen transport, ion transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane REB1, ZAP1
Main: energy derivation by oxidation of organic compounds (0.60) ubiquinol-cytochrome c reductase activity (0.20) cytoplasm (1.00) MBP1 (0.33)
Score: 0.30 0.00 1.00 0.067
P-value: 4.150E-03 (glutamate biosynthesis) 4.968E-02 (oxidoreductase activity) 8.141E-02 (mitochondrion) 2.025E-01 (MBP1)

m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) AND HAP234(1) => SimExpr(YPL078C) OR SimExpr(other) : 5 1

EXPR: (0.207) m_tricarboxylic-acid_pathway_orfnum2SD_n3 (P < 0.038) HAP234 (P < 0.100)

ORF SYMBOL P F C TF
|YDL240W| LRG1 small GTPase mediated signal transduction, cell wall biosynthesis (sensu Fungi) ->
signal transduction, cell organization and biogenesis, biosynthesis Rho GTPase activator activity ->
Rho GTPase activator activity FKH1
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
mitochondrion MET4
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytosol, mitochondrion CIN5, YAP6
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
mitochondrion, respiratory chain complex III, inner membrane HAP4, MBP1
YLR168C NO SYMBOL HAP4
YPL078C ATP4 ATP synthesis coupled proton transport ->
transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
mitochondrion, proton-transporting ATP synthase complex\, coupling factor F(o), proton-transporting ATP synthase complex, proton-transporting two-sector ATPase complex, inner membrane REB1, ZAP1
Main: biosynthesis (0.60) Rho GTPase activator activity (0.20) mitochondrion (1.00) HAP4 (0.33)
Score: 0.50 0.00 1.00 0.067
P-value: 2.968E-03 (glutamate biosynthesis) 2.882E-01 (oxidoreductase activity) 3.887E-02 (mitochondrion) 2.259E-02 (HAP4)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n7(1) => SimExpr(YPL078C) OR SimExpr(other) : 5 2

m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND mRRPE(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YOR133W) OR SimExpr(other) : 6 1

EXPR: (0.200) mRRPE (P < 0.001) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.002)

ORF SYMBOL P F C TF
YDR039C ENA2 sodium ion transport ->
transport P-type ATPase activity ->
purine nucleotide binding, primary active transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides plasma membrane ->
plasma membrane SFP1
YNR046W NO SYMBOL ABF1
YDR429C TIF35 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation factor activity\, nucleic acid binding eukaryotic translation initiation factor 3 complex ->
cytoplasm RFX1
YOR133W EFT1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex
YLR372W SUR4 fatty acid biosynthesis, post-Golgi transport, sphingolipid biosynthesis, fatty acid elongation ->
transport, lipid metabolism, biosynthesis, vesicle-mediated transport, organic acid metabolism fatty acid elongase activity ->
transferase activity\, transferring acyl groups endoplasmic reticulum membrane, endoplasmic reticulum ->
cytoplasm, endomembrane system SRD1
YML125C NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
|YDR038C| ENA5 sodium ion transport ->
transport P-type ATPase activity ->
purine nucleotide binding, primary active transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides plasma membrane ->
plasma membrane INO2
Main: biosynthesis (0.60) primary active transporter activity (0.40) cytoplasm (0.60) ABF1 (0.17)
Score: 0.60 0.20 0.40 0.000
P-value: 8.336E-04 (sodium ion transport) 3.428E-02 (P-type ATPase activity) 4.928E-01 (plasma membrane) 7.855E-01 (MAL13)

m_RPE34(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YNL302C) OR SimExpr(other) : 8 2

m_RPE6(1) => SimExpr(YNL302C) OR SimExpr(other) : 18 8

m_RPE57(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YNL302C) OR SimExpr(other) : 7 3

EXPR: (0.198) m_RPE57 (P < 0.084) m_cell_death_orfnum2SD_n8 (P < 0.002)

RAP1(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn(1) => SimExpr(YNL302C) OR SimExpr(other) : 6 1

m_other_proteolytic_degradation_orfnum2SD_n12(1) AND m_mitochondrial_biogenesis_orfnum2SD_n5(1) => SimExpr(YNL302C) OR SimExpr(other) : 5 1

EXPR: (0.194) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.001) m_other_proteolytic_degradation_orfnum2SD_n12 (P < 0.013)

ORF SYMBOL P F C TF
YOL019W NO SYMBOL SWI4
|YDR111C| NO SYMBOL RAP1
YNL302C RPS19B protein biosynthesis ->
macromolecule biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, RAP1
YNL175C NOP13 RNA binding ->
RNA binding nucleolus, nucleoplasm ->
nucleus INO2, INO4
YOR198C BFR1 cytokinesis, spindle assembly, regulation of mitosis, bud growth, meiosis ->
cytokinesis, cytoplasm organization and biogenesis, budding, cell cycle, mitotic cell cycle RNA binding ->
RNA binding polysome, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system, ribonucleoprotein complex NDD1, REB1
YNL070W TOM7 mitochondrial translocation ->
cytoplasm organization and biogenesis, intracellular transport, protein metabolism, protein transport protein transporter activity ->
protein transporter activity mitochondrial outer membrane translocase complex ->
cytoplasm, outer membrane HAP4, STP2
Main: cytoplasm organization and biogenesis (0.67) RNA binding (0.50) cytoplasm (0.75) RAP1 (0.33)
Score: 0.67 0.17 0.50 0.067
P-value: 1.889E+00 (organelle organization and biogenesis) 3.863E-01 (RNA binding) 6.209E-01 (ribosome) 4.189E-01 (RAP1)

RAP1(1) AND m_RPE8(1) => SimExpr(YNL302C) : 9

RAP1(1) AND m_RPE57(1) => SimExpr(YNL302C) : 8

m_RPE72(1) AND m_RPE8(1) => SimExpr(YNL302C) : 5

RAP1(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YNL302C) : 8

m_RPE57(1) AND m_RPE6(1) => SimExpr(YNL302C) : 7

m_RPE6(1) AND m_RPE34(1) => SimExpr(YNL302C) : 6

RAP1(1) AND m_RPE17(1) => SimExpr(YNL302C) : 5

RAP1(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YNL302C) : 5

RAP1(1) AND m_RPE34(1) => SimExpr(YNL302C) : 8

RAP1(1) AND m_RPE6(1) => SimExpr(YNL302C) : 9

m_RPE57(1) AND m_RPE34(1) => SimExpr(YNL302C) : 5

RAP1(1) AND m_RPE72(1) => SimExpr(YNL302C) : 5

m_RPE8(1) AND m_RPE17(1) => SimExpr(YNL302C) : 5

m_RPE57(1) AND m_RPE8(1) => SimExpr(YNL302C) : 5

m_RPE6(1) AND m_RPE8(1) => SimExpr(YNL302C) : 8

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND CSRE(1) => SimExpr(YNL208W) OR SimExpr(other) : 8 3

EXPR: (0.226) m_regulation_of_amino-acid_metabolism_orfnum2SD_n15 (P < 0.014) CSRE (P < 0.002)

ORF SYMBOL P F C TF
|YPL050C| MNN9 N-linked glycosylation ->
biosynthesis, protein metabolism mannosyltransferase activity ->
mannosyltransferase activity membrane, Golgi cis-face, mannosyltransferase complex ->
membrane, cytoplasm IME4, MBP1, NDD1, PDR1, SKN7, SMP1, SWI5
YOR003W YSP3 protein catabolism ->
catabolism, protein metabolism peptidase activity ->
peptidase activity
YNL208W NO SYMBOL INO2
YLR205C HMX1 iron ion homeostasis ->
cell homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, membrane HAP4, MBP1
|YKL181W| PRS1 histidine biosynthesis, tryptophan biosynthesis, purine salvage, 'de novo' IMP biosynthesis, 'de novo' pyrimidine base biosynthesis ->
amine metabolism, nucleotide biosynthesis, purine ribonucleotide metabolism, aromatic compound metabolism, amino acid derivative biosynthesis, biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, amino acid and derivative metabolism, organic acid metabolism, heterocycle metabolism ribose-phosphate pyrophosphokinase activity ->
ribose-phosphate pyrophosphokinase activity
YGR209C TRX2 vacuole inheritance, DNA dependent DNA replication, response to oxidative stress, vacuole fusion (non-autophagic), regulation of redox homeostasis ->
oxygen and reactive oxygen species metabolism, cell organization and biogenesis, cell homeostasis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, response to biotic stimulus thiol-disulfide exchange intermediate activity ->
thiol-disulfide exchange intermediate activity cytosol, vacuole (sensu Fungi) ->
cytoplasm
|YPR162C| ORC4 pre-replicative complex formation and maintenance, DNA replication initiation, chromatin silencing at HML and HMR (sensu Saccharomyces) ->
nuclear organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription, DNA metabolism DNA replication origin binding ->
DNA replication origin binding nuclear origin of replication recognition complex ->
chromosome, nucleoplasm, nucleus
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
YLR297W NO SYMBOL
YOR299W BUD7 bud site selection ->
cell proliferation, cell organization and biogenesis HSF1, MTH1
Main: cell organization and biogenesis (0.33) structural constituent of cell wall (0.12) membrane (0.50) SKN7 SMP1 MBP1 (0.33)
Score: 0.28 0.00 0.33 0.200
P-value: 4.696E-01 (DNA dependent DNA replication) 2.799E-01 (oxidoreductase activity) 2.878E+00 (membrane) 2.641E-01 (SMP1)

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n8.scn(1) => SimExpr(YNL208W) OR SimExpr(other) : 6 2

m_MERE4(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YNL208W) OR SimExpr(other) : 8 4

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_MERE4(1) => SimExpr(YNL208W) OR SimExpr(other) : 8 3

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YNL208W) : 6

m_regulation_of_amino-acid_metabolism_orfnum2SD_n15(1) AND PHO(1) => SimExpr(YNL208W) : 5

EXPR: (0.161) m_regulation_of_amino-acid_metabolism_orfnum2SD_n15 (P < 0.001) PHO (P < 0.000)

ORF SYMBOL P F C TF
YPR183W DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YNL208W NO SYMBOL INO2
YJR122W CAF17 YAP1
YJR009C TDH2 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity cytosol, lipid particle, cell wall, cytoplasm ->
cytoplasm, cell wall CBF1, GCR1, GCR2
YJR044C VPS55 late endosome to vacuole transport ->
cell organization and biogenesis, transport late endosome ->
cytoplasm ACE2, CAD1, FZF1, GAL4, GAT3, GCR2, HIR1, IME4, MBP1, NDD1, PDR1, RGM1, SMP1, SWI4, SWI5, YAP5, ZMS1
Main: biosynthesis (0.67) dolichyl-phosphate beta-D-mannosyltransferase activity (0.50) cytoplasm (1.00) GCR2 SWI5 (0.40)
Score: 0.33 0.00 1.00 0.200
P-value: 1.467E+00 (biosynthesis) 2.509E+00 (enzyme activity) 3.185E+00 (cytoplasm) 8.412E-02 (GCR2)

m_nutritional_response_pathway_orfnum2SD_n7(1) AND STRE'(1) => SimExpr(YDR511W) OR SimExpr(other) : 5 2

m_c-compound_and_carbohydrate_utilization_orfnum2SD_n31(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YDR511W) OR SimExpr(other) : 5 2

EXPR: (0.201) m_anion_transporters_orfnum2SD_n20 (P < 0.001) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n31 (P < 0.011)

ORF SYMBOL P F C TF
|YNL241C| ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YDR511W ACN9 carbon utilization by utilization of organic compounds, gluconeogenesis ->
carbon utilization, alcohol metabolism, carbohydrate metabolism, biosynthesis, energy pathways mitochondrial intermembrane space ->
cytoplasm MBP1, STB1
YGL062W PYC1 NADPH regeneration, gluconeogenesis ->
coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways pyruvate carboxylase activity ->
pyruvate carboxylase activity cytosol ->
cytoplasm DIG1, GCR1, STE12
|YIR016W| NO SYMBOL DAL82, RAP1
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
phosphoric ester hydrolase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
YGR212W NO SYMBOL GCR2
YIL124W AYR1 phosphatidic acid biosynthesis ->
biosynthesis, membrane lipid metabolism, organic acid metabolism, lipid metabolism acylglycerone-phosphate reductase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor endoplasmic reticulum, lipid particle, cytoplasm ->
cytoplasm
Main: carbohydrate metabolism (0.80) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.50) cytoplasm (0.80) MBP1 (0.40)
Score: 0.80 0.17 0.60 0.100
P-value: 6.988E-03 (NADPH regeneration) 6.354E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 3.294E+00 (cytoplasm) 3.498E-01 (MBP1)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_trna_processing_orfnum2SD_n9(1) => SimExpr(YDL126C) OR SimExpr(other) : 5 1

EXPR: (0.191) m_trna_processing_orfnum2SD_n9 (P < 0.002) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.003)

ORF SYMBOL P F C TF
|YNL241C| ZWF1 pentose-phosphate shunt ->
alcohol catabolism, carbohydrate metabolism, coenzyme metabolism, monosaccharide metabolism, water-soluble vitamin metabolism, carbohydrate catabolism, energy derivation by oxidation of organic compounds glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YDR284C DPP1 phospholipid metabolism ->
membrane lipid metabolism diacylglycerol pyrophosphate phosphatase activity, phosphatidate phosphatase activity ->
hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides, phosphoric ester hydrolase activity vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole ABF1, FKH1, GCR2, GLN3, GTS1, RIM101, RTG1, SWI6
YDL126C CDC48 ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism ->
secretory pathway, cell cycle, programmed cell death, protein transport, macromolecule catabolism, vesicle-mediated transport, protein metabolism ATPase activity ->
adenyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides nucleus, microsome, endoplasmic reticulum, cytosol ->
nucleus, membrane fraction, cytoplasm DAL82, MAL33, SWI4
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to DNA damage, cytoplasm organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine biosynthesis, cytoplasm organization and biogenesis, amine metabolism, amino acid and derivative metabolism, carboxylic acid metabolism ketol-acid reductoisomerase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrion ->
cytoplasm GCN4, MET4
YNL287W SEC21 ER to Golgi transport, retrograde (Golgi to ER) transport ->
intracellular transport, secretory pathway, vesicle-mediated transport COPI vesicle coat ->
cytoplasm ABF1
Main: vesicle-mediated transport (0.33) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.40) cytoplasm (1.00) ABF1 NDD1 SWI6 (0.33)
Score: 0.13 0.20 1.00 0.200
P-value: 1.210E-01 (mitochondrion organization and biogenesis) 6.909E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 9.728E-01 (cytoplasm) 3.042E-01 (NDD1)

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND m_g-proteins_orfnum2SD_n11(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) => SimExpr(YMR134W) OR SimExpr(other) : 5 1

EXPR: (0.198) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.001) m_other_pheromone_response_activities_orfnum2SD_n8 (P < 0.004)

ORF SYMBOL P F C TF
YMR284W YKU70 double-strand break repair via nonhomologous end-joining, telomere maintenance, double-strand break repair via homologous recombination, chromatin assembly/disassembly, transcriptional gene silencing ->
cell organization and biogenesis, regulation of transcription, response to biotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription\, DNA-dependent damaged DNA binding ->
damaged DNA binding nuclear membrane, nuclear chromatin, nuclear telomeric heterochromatin ->
nucleus, chromosome\, telomeric region, chromosome, endomembrane system
YMR139W RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MAL33, YJL206C
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YIL119C RPI1 RAS protein signal transduction, thiamin biosynthesis ->
signal transduction, biosynthesis, vitamin metabolism small GTPase regulatory/interacting protein activity ->
small GTPase regulatory/interacting protein activity nucleus ->
nucleus CIN5, CUP9, INO4, IXR1, MOT3, NRG1, RLM1, ROX1, SKO1, SOK2, YAP6
|YIL066C| RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity cytoplasm ->
cytoplasm RFX1, STB1
YMR134W NO SYMBOL BAS1, CIN5, FZF1, HAP3, RCS1
Main: biosynthesis (0.40) aconitate hydratase activity (0.20) cytoplasm (0.50) CIN5 (0.60)
Score: 0.20 0.00 0.33 0.300
P-value: 3.842E-01 (response to stress) 2.077E+00 (enzyme activity) 4.113E+00 (nucleus) 5.224E-02 (CIN5)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YMR134W) OR SimExpr(other) : 7 3

EXPR: (0.219) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.001) m_other_signal-transduction_activities_orfnum2SD_n8 (P < 0.006)

m_organization_of_plasma_membrane_orfnum2SD_n15(1) AND m_other_signal-transduction_activities_orfnum2SD_n8(1) => SimExpr(YMR134W) OR SimExpr(other) : 5 2

EXPR: (0.205) m_other_signal-transduction_activities_orfnum2SD_n8 (P < 0.001) m_organization_of_plasma_membrane_orfnum2SD_n15 (P < 0.013)

ORF SYMBOL P F C TF
|YNL097C| PHO23 chromatin modification ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleus ->
nucleus MAC1
YKL207W NO SYMBOL
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid permease activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YML116W ATR1 multidrug transport ->
transport, response to abiotic stimulus multidrug efflux pump activity ->
multidrug efflux pump activity plasma membrane ->
plasma membrane CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YKR091W SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm DIG1, RLM1, STE12
|YIL057C| NO SYMBOL RAP1
YMR134W NO SYMBOL BAS1, CIN5, FZF1, HAP3, RCS1
Main: transport (0.50) amino acid permease activity (0.50) plasma membrane (0.50) CIN5 (0.33)
Score: 0.33 0.00 0.17 0.067
P-value: 3.490E+00 (transport) 5.780E-01 (transporter activity) 4.224E-01 (plasma membrane) 8.682E-01 (CIN5)

m_g-proteins_orfnum2SD_n12(1) AND m_other_nutritional-response_activities_orfnum2SD_n10(1) AND PHO(1) => SimExpr(YMR134W) OR SimExpr(other) : 5 2

EXPR: (0.235) m_g-proteins_orfnum2SD_n12 (P < 0.011) PHO (P < 0.024) m_other_nutritional-response_activities_orfnum2SD_n10 (P < 0.013)

ORF SYMBOL P F C TF
YKL062W MSN4 regulation of transcription\, DNA-dependent, response to stress ->
response to stress, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity, DNA binding ->
transcription factor activity, DNA binding nucleus, cytoplasm ->
nucleus, cytoplasm ASH1, HAL9, PHD1, RAP1, SKN7
YHR083W NO SYMBOL DIG1, STE12
|YKL198C| PTK1 polyamine transport ->
transport protein kinase activity ->
protein kinase activity INO2
|YPL032C| SVL3 endocytosis ->
transport FKH1, HSF1
YKR091W SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm DIG1, RLM1, STE12
YMR134W NO SYMBOL BAS1, CIN5, FZF1, HAP3, RCS1
YOR270C VPH1 polyphosphate metabolism, vacuolar acidification ->
phosphorus metabolism, cell homeostasis, cell organization and biogenesis, transport hydrogen-transporting ATPase V0 domain, vacuole ->
cytoplasm ABF1
Main: transport (0.60) DNA binding (0.50) cytoplasm (1.00) STE12 DIG1 (0.29)
Score: 0.40 0.00 1.00 0.048
P-value: 1.245E+00 (transport) 2.000E+00 4.385E+00 (cytoplasm) 8.354E-02 (DIG1)

m_RPE8(1) AND m_other_intracellular-transport_activities_orfnum2SD_n6(1) => SimExpr(YKL122C) OR SimExpr(other) : 5 2

m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) AND m_other_transport_facilitators_orfnum2SD_n10(1) => SimExpr(YKL122C) OR SimExpr(other) : 5 1

m_other_transport_facilitators_orfnum2SD_n10(1) AND BAS1(1) => SimExpr(YKL122C) OR SimExpr(other) : 5 2

m_other_transport_facilitators_orfnum2SD_n10(1) AND m_RPE8(1) => SimExpr(YKL122C) OR SimExpr(other) : 5 1

EXPR: (0.169) m_RPE8 (P < 0.013) m_other_transport_facilitators_orfnum2SD_n10 (P < 0.001)

SWI5(1) AND REB1(1) AND SCB(1) => SimExpr(YPL237W) OR SimExpr(other) : 6 2

EXPR: (0.219) SWI5 (P < 0.000) REB1 (P < 0.006) SCB (P < 0.001)

ORF SYMBOL P F C TF
YMR186W HSC82 protein folding, response to stress ->
protein metabolism, response to stress cation-transporting ATPase activity, chaperone activity ->
cation-transporting ATPase activity, chaperone activity BAS1, HAP2, HSF1, INO4, REB1, ROX1
YMR121C RPL15B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex REB1
YPL237W SUI3 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex
YMR002W NO SYMBOL NDD1, REB1, SWI6
|YOL006C| TOP1 negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration ->
cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA topoisomerase type I activity ->
DNA topoisomerase type I activity nucleus ->
nucleus REB1
|YGR280C| PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YDL232W OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
Main: biosynthesis (0.57) RNA binding (0.29) cytoplasm (0.50) REB1 (1.00)
Score: 0.48 0.05 0.27 1.000
P-value: 7.827E-01 (protein biosynthesis) 4.595E-01 (binding) 1.044E+00 (ribosome) 8.374E-07 (REB1)

m_RRSE3(1) AND m_nutritional_response_pathway_orfnum2SD_n3(1) => SimExpr(YNR071C) OR SimExpr(other) : 7 2

EXPR: (0.214) m_RRSE3 (P < 0.000) m_nutritional_response_pathway_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
YOR040W GLO4 carbohydrate metabolism ->
carbohydrate metabolism hydroxyacylglutathione hydrolase activity ->
hydroxyacylglutathione hydrolase activity mitochondrion, mitochondrial matrix ->
cytoplasm
YOR389W NO SYMBOL MCM1, YJL206C
YNR071C NO SYMBOL YJL206C
YDR438W NO SYMBOL CBF1
YHR211W FLO5 flocculation ->
flocculation cell adhesion molecule activity ->
cell adhesion molecule activity cell wall (sensu Fungi) ->
cell wall GRF10(Pho2), PHO4
|YOR198C| BFR1 cytokinesis, spindle assembly, regulation of mitosis, bud growth, meiosis ->
cytokinesis, spindle assembly, regulation of mitosis, bud growth, meiosis RNA binding ->
RNA binding polysome, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, membrane, ribonucleoprotein complex NDD1, REB1
|YOR306C| MCH5 transport ->
transport transporter activity ->
transporter activity membrane ->
membrane CIN5, PUT3
YIL099W SGA1 sporulation (sensu Saccharomyces) ->
sporulation (sensu Saccharomyces) glucan 1\,4-alpha-glucosidase activity ->
glucan 1\,4-alpha-glucosidase activity vacuole (sensu Fungi) ->
cytoplasm ASH1, CIN5, CUP9, MOT3, NRG1, PHD1, ROX1, SKN7, SOK2, YAP6
YMR018W NO SYMBOL PHD1
Main: sporulation (sensu Saccharomyces) (0.20) RNA binding (0.20) cytoplasm (0.60) CIN5 PHD1 YJL206C (0.25)
Score: 0.00 0.00 0.40 0.107
P-value: 4.210E+00 (cellular process) 2.166E+00 (hydrolase activity) 3.889E+00 (membrane) 8.590E-02 (YJL206C)

m_allantoin_and_allantoate_transporters_orfnum2SD_n12(1) AND m_phosphate_transport_orfnum2SD_n13(1) => SimExpr(YIL167W) OR SimExpr(other) : 7 3

EXPR: (0.228) m_phosphate_transport_orfnum2SD_n13 (P < 0.003) m_allantoin_and_allantoate_transporters_orfnum2SD_n12 (P < 0.001)

ORF SYMBOL P F C TF
YGL164C YRB30 protein binding, enzyme regulator activity ->
protein binding, enzyme regulator activity cytoplasm, nucleus ->
cytoplasm, nucleus HIR1, IME4
YML005W NO SYMBOL USV1
YPR147C NO SYMBOL
|YGR146C| NO SYMBOL HSF1
YIL167W NO SYMBOL
YOR173W DCS2 CAD1
|YPR117W| NO SYMBOL IME4, MBP1, SFP1
|YPL191C| NO SYMBOL RFX1
YIL045W PIG2 enzyme regulator activity ->
enzyme regulator activity CIN5
YGR260W TNA1 nicotinamide mononucleotide transport ->
nicotinamide mononucleotide transport nicotinamide mononucleotide permease activity ->
nicotinamide mononucleotide permease activity integral to plasma membrane ->
integral to plasma membrane HIR2, SUM1
Main: nicotinamide mononucleotide transport (1.00) enzyme regulator activity (0.67) cytoplasm (0.50) IME4 (0.25)
Score: 0.00 0.33 0.00 0.036
P-value: 0.000E+00 1.704E-01 (enzyme regulator activity) 3.000E+00 4.410E-02 (IME4)

m_organization_of_plasma_membrane_orfnum2SD_n15(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YLR360W) OR SimExpr(other) : 6 2

EXPR: (0.208) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) m_organization_of_plasma_membrane_orfnum2SD_n15 (P < 0.002)

ORF SYMBOL P F C TF
|YIL056W| NO SYMBOL CUP9, HAL9, MTH1, PHD1, ROX1, SWI4, YAP6
YAL002W VPS8 late endosome to vacuole transport ->
cell organization and biogenesis, transport membrane fraction ->
membrane fraction MBP1, PHD1
|YOR047C| STD1 signal transduction, glucose metabolism, salinity response, regulation of transcription from Pol II promoter ->
signal transduction, alcohol metabolism, response to abiotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism protein kinase activator activity ->
protein kinase activator activity nucleus, plasma membrane ->
nucleus, plasma membrane CIN5
YML116W ATR1 multidrug transport ->
transport, response to abiotic stimulus multidrug efflux pump activity ->
multidrug efflux pump activity plasma membrane ->
plasma membrane CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YLR360W VPS38 late endosome to vacuole transport ->
cell organization and biogenesis, transport membrane fraction ->
membrane fraction ARG80
YDR003W NO SYMBOL ARG80, FKH1, GCR2, GLN3
YIL068C SEC6 cytokinesis, Golgi to plasma membrane transport, nonselective vesicle docking, nonselective vesicle fusion, polar budding, establishment of cell polarity (sensu Saccharomyces), endocytosis ->
cell proliferation, budding, transport, cytoplasm organization and biogenesis actin cap (sensu Saccharomyces), exocyst ->
actin cap (sensu Saccharomyces), exocyst
YGR086C PIL1 ASH1, SWI5
Main: transport (0.80) protein kinase activator activity (0.50) membrane fraction (0.40) PHD1 (0.43)
Score: 0.70 0.00 0.20 0.238
P-value: 1.024E-02 (late endosome to vacuole transport) 2.000E+00 4.040E-02 (membrane fraction) 2.704E-02 (PHD1)

BAS1(1) AND m_detoxificaton_orfnum2SD_n39(1) => SimExpr(YKR091W) OR SimExpr(other) : 5 2

EXPR: (0.203) m_detoxificaton_orfnum2SD_n39 (P < 0.002) BAS1 (P < 0.000)

ORF SYMBOL P F C TF
YDR085C AFR1 regulation of G-protein coupled receptor protein signaling pathway, signal transduction during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus receptor signaling protein activity ->
receptor signaling protein activity shmoo tip ->
shmoo tip FKH1, RLM1, SFL1
YLR398C SKI2 mRNA catabolism, regulation of translation ->
catabolism, biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism RNA helicase activity, translation repressor activity ->
RNA binding, translation repressor activity cytoplasm ->
cytoplasm MTH1
YNR052C POP2 regulation of transcription from Pol II promoter, poly(A) tail shortening ->
catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, RNA metabolism 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding CCR4-NOT core complex, cytoplasm ->
CCR4-NOT core complex, cytoplasm ABF1, ARG81, HIR1, SFL1
YKR091W SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm DIG1, RLM1, STE12
|YNL098C| RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides plasma membrane ->
plasma membrane ACE2, SKN7
|YGR061C| ADE6 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism phosphoribosylformylglycinamidine synthase activity ->
ligase activity\, forming carbon-nitrogen bonds BAS1, CHA4
YOR153W PDR5 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
purine nucleotide binding, multidrug transporter activity, primary active transporter activity, hydrolase activity\, acting on acid anhydrides plasma membrane ->
plasma membrane YAP6
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.57) RNA binding (0.33) cytoplasm (0.50) RLM1 SFL1 (0.29)
Score: 0.38 0.13 0.27 0.095
P-value: 2.361E-02 (G-protein coupled receptor protein signaling pathway) 9.476E-01 (hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides) 4.928E-01 (plasma membrane) 4.539E-02 (SFL1)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_other_cation_transporters_orfnum2SD_n3(1) => SimExpr(YKR091W) OR SimExpr(other) : 5 2

EXPR: (0.210) m_other_cation_transporters_orfnum2SD_n3 (P < 0.000) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.000)

ORF SYMBOL P F C TF
|YJL164C| TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
cell organization and biogenesis, phosphorus metabolism, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
|YJL165C| HAL5 cation homeostasis ->
cell homeostasis protein kinase activity ->
protein kinase activity
YKR091W SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm DIG1, RLM1, STE12
YDL185W TFP1 intron homing, vacuolar acidification, protein metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell homeostasis, protein metabolism, cell organization and biogenesis, transport hydrogen-exporting ATPase activity, endodeoxyribonuclease activity ->
ATP binding, deoxyribonuclease activity, hydrogen ion transporter activity, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides, endonuclease activity vacuolar membrane (sensu Fungi), hydrogen-transporting ATPase V1 domain ->
cytoplasm, vacuole SWI4
YOR153W PDR5 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
ATP binding, multidrug transporter activity, P-P-bond-hydrolysis-driven transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane YAP6
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: cell organization and biogenesis (0.29) ATP binding (0.40) cytoplasm (0.80) SWI4 YAP6 (0.33)
Score: 0.24 0.20 0.60 0.133
P-value: 1.120E-01 (cation homeostasis) 1.665E-01 (P-P-bond-hydrolysis-driven transporter activity) 3.016E+00 (membrane) 4.592E-01 (YAP6)

STRE'(1) AND m_MERE11(1) => SimExpr(YOR062C) OR SimExpr(other) : 11 2

EXPR: (0.204) m_MERE11 (P < 0.001) STRE' (P < 0.004)

m_OCSE15(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YOR062C) OR SimExpr(other) : 5 2

EXPR: (0.220) m_OCSE15 (P < 0.013) m_amino-acid_transport_orfnum2SD_n18 (P < 0.003)

ORF SYMBOL P F C TF
YOR347C PYK2 pyruvate metabolism, glycolysis ->
pyruvate metabolism, glucose catabolism, main pathways of carbohydrate metabolism pyruvate kinase activity ->
pyruvate kinase activity cytosol ->
cytoplasm ZMS1
YNL069C RPL16B protein biosynthesis ->
protein biosynthesis RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
|YDR352W| NO SYMBOL
YGR121C MEP1 ammonium transport ->
ammonium transport ammonium transporter activity ->
ammonium transporter activity plasma membrane ->
plasma membrane CIN5
|YFL044C| NO SYMBOL
YOR062C NO SYMBOL GRF10(Pho2)
YPR074C TKL1 pentose-phosphate shunt ->
glucose catabolism, main pathways of carbohydrate metabolism, nicotinamide metabolism transketolase activity ->
transketolase activity cytoplasm ->
cytoplasm REB1
Main: glucose catabolism (0.50) ammonium transporter activity (0.25) cytoplasm (0.75) PDR1 (0.20)
Score: 0.17 0.00 0.50 0.000
P-value: 4.125E-02 (hexose catabolism) 1.225E+00 (transferase activity) 1.086E+00 (cytosol) 4.721E-01 (ZMS1)

m_amino-acid_transport_orfnum2SD_n3(1) AND STRE'(1) => SimExpr(YOR062C) OR SimExpr(other) : 5 2

EXPR: (0.198) STRE' (P < 0.010) m_amino-acid_transport_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
|YMR090W| NO SYMBOL RTG1
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
|YMR003W| NO SYMBOL
YFR015C GSY1 glycogen metabolism ->
polysaccharide metabolism, energy derivation by oxidation of organic compounds glycogen (starch) synthase activity ->
glycogen (starch) synthase activity INO4
YGR086C PIL1 ASH1, SWI5
YPL111W CAR1 arginine catabolism to ornithine ->
amine catabolism, amine metabolism, urea cycle intermediate metabolism, amino acid and derivative metabolism, carboxylic acid metabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YOR062C NO SYMBOL GRF10(Pho2)
Main: amino acid and derivative metabolism (0.67) glycogen (starch) synthase activity (0.33) cytoplasm (1.00) MET4 (0.17)
Score: 0.67 0.00 1.00 0.000
P-value: 3.730E-02 (glutamine family amino acid metabolism) 2.414E+00 (enzyme activity) 4.869E+00 (cytoplasm) 4.708E-01 (ASH1)

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YOR062C) OR SimExpr(other) : 5 1

EXPR: (0.171) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.000) m_peroxisomal_transport_orfnum2SD_n22 (P < 0.000)

ORF SYMBOL P F C TF
YPR134W MSS18 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism MSS11
YOR062C NO SYMBOL GRF10(Pho2)
|YDR381W| YRA1 mRNA-nucleus export ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding transcription export complex ->
transcription export complex ARO80
YNL045W NO SYMBOL MSN1
YOR066W NO SYMBOL MBP1, MCM1
YOR299W BUD7 bud site selection ->
cell proliferation, cell organization and biogenesis HSF1, MTH1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67) RNA binding (1.00) transcription export complex (1.00) MTH1 (0.17)
Score: 0.33 0.00 0.00 0.000
P-value: 3.502E+00 (nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism) 0.000E+00 0.000E+00 2.043E-01 (MSN1)

m_nitrogen_and_sulphur_metabolism_orfnum2SD_n22(1) AND STRE'(1) => SimExpr(YOR062C) OR SimExpr(other) : 5 2

m_OCSE15(1) AND m_organization_of_chromosome_structure_orfnum2SD_n17(1) => SimExpr(YOR062C) OR SimExpr(other) : 5 2

EXPR: (0.214) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.005) m_OCSE15 (P < 0.006)

ORF SYMBOL P F C TF
YOR347C PYK2 pyruvate metabolism, glycolysis ->
organic acid metabolism, alcohol metabolism, pyruvate dehydrogenase bypass, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism pyruvate kinase activity ->
pyruvate kinase activity cytosol ->
cytoplasm ZMS1
|YOL012C| HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging nucleic acid binding ->
nucleic acid binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
|YMR080C| NAM7 mRNA catabolism, mRNA catabolism\, nonsense-mediated, regulation of translational termination ->
catabolism, macromolecule biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism ATPase activity, ATP dependent helicase activity, nucleic acid binding ->
ATPase activity, ATP dependent helicase activity, nucleic acid binding polysome, cytoplasm ->
cytoplasm, ribonucleoprotein complex
YDR359C VID21 ABF1
YKR093W PTR2 peptide transport ->
transport peptide transporter activity ->
peptide transporter activity plasma membrane ->
plasma membrane CUP9, DAL81, FKH1, FKH2, HSF1, MET4, SKN7, SWI4
YJR123W RPS5 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GRF10(Pho2), HSF1, MSN4, YAP1
YOR062C NO SYMBOL GRF10(Pho2)
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.40) nucleic acid binding (0.40) cytoplasm (0.60) SWI4 GRF10(Pho2) HSF1 (0.33)
Score: 0.30 0.10 0.30 0.200
P-value: 1.378E+00 (catabolism) 1.725E+00 (nucleic acid binding) 8.247E-01 (ribosome) 1.055E-01 (GRF10(Pho2))

m_nitrogen_and_sulphur_metabolism_orfnum2SD_n22(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YOR062C) OR SimExpr(other) : 6 2

EXPR: (0.224) m_peroxisomal_transport_orfnum2SD_n22 (P < 0.001) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n22 (P < 0.023)

ORF SYMBOL P F C TF
YJL172W CPS1 nitrogen metabolism, proteolysis and peptidolysis ->
nitrogen metabolism, catabolism, protein metabolism gly-X carboxypeptidase activity ->
gly-X carboxypeptidase activity vacuole (sensu Fungi) ->
cytoplasm PHO4
|YJL042W| MHP1 microtubule stabilization, cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton microtubule ->
cytoplasm CRZ1, GAL4, GAT3, PDR1, RGM1, YAP5
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YHR171W APG7 protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport ubiquitin-like conjugating enzyme activity ->
ubiquitin-like conjugating enzyme activity GLN3, LEU3, RCS1
YOR062C NO SYMBOL GRF10(Pho2)
|YGR050C| NO SYMBOL DAL82, FKH2, HSF1, INO4, MAL13, NRG1, RAP1, SKN7, SWI4
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
YMR086W NO SYMBOL FKH1
Main: cell organization and biogenesis (0.60) ubiquitin-like conjugating enzyme activity (0.20) cytoplasm (0.75) SKN7 (0.25)
Score: 0.40 0.00 0.50 0.036
P-value: 2.956E+00 (organelle organization and biogenesis) 1.900E+00 (hydrolase activity) 3.480E+00 (membrane) 8.019E-01 (SKN7)

BAS1(1) AND m_lysosomal_and_vacuolar_degradation_orfnum2SD_n8(1) => SimExpr(YKL080W) OR SimExpr(other) : 5 2

EXPR: (0.242) m_lysosomal_and_vacuolar_degradation_orfnum2SD_n8 (P < 0.035) BAS1 (P < 0.015)

ORF SYMBOL P F C TF
|YMR120C| ADE17 'de novo' IMP biosynthesis ->
'de novo' IMP biosynthesis IMP cyclohydrolase activity, phosphoribosylaminoimidazole-carboxamide formyltransferase activity ->
IMP cyclohydrolase activity, phosphoribosylaminoimidazole-carboxamide formyltransferase activity cytosol ->
cytoplasm BAS1
YOL092W NO SYMBOL MAC1
|YLR394W| CST9 DNA replication and chromosome cycle ->
DNA replication and chromosome cycle DNA binding ->
DNA binding SMP1
YMR148W NO SYMBOL
YKL080W VMA5 vacuolar acidification ->
vacuolar acidification hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole
YOL153C NO SYMBOL
YML078W CPR3 protein folding ->
protein folding peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity mitochondrion ->
cytoplasm
Main: vacuolar acidification (0.25) peptidyl-prolyl cis-trans isomerase activity (0.33) cytoplasm (1.00) MAC1 (0.33)
Score: 0.00 0.00 1.00 0.000
P-value: 5.723E+00 (cell growth and/or maintenance) 2.849E+00 (enzyme activity) 4.385E+00 (cytoplasm) 3.676E-01 (SMP1)

m_pentose-phosphate_pathway_orfnum2SD_n14(1) AND m_g-proteins_orfnum2SD_n12(1) AND m_morphogenesis_orfnum2SD_n5(1) => SimExpr(YDR141C) OR SimExpr(other) : 5 2

EXPR: (0.216) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_pentose-phosphate_pathway_orfnum2SD_n14 (P < 0.000) m_morphogenesis_orfnum2SD_n5 (P < 0.000)

ORF SYMBOL P F C TF
|YOL101C| NO SYMBOL
YDL134C PPH21 G1/S transition of mitotic cell cycle, protein biosynthesis, actin filament organization, mitotic spindle checkpoint, bud growth, protein amino acid dephosphorylation ->
biosynthesis, cell organization and biogenesis, asexual reproduction, phosphorus metabolism, cell proliferation, cell cycle, protein metabolism protein phosphatase type 2A activity ->
protein phosphatase type 2A activity protein phosphatase type 2A complex ->
protein phosphatase type 2A complex MCM1, MET31
YDR293C SSD1 cell wall organization and biogenesis ->
cell organization and biogenesis RNA binding ->
RNA binding cytoplasm ->
cytoplasm
YFR015C GSY1 glycogen metabolism ->
carbohydrate metabolism, energy pathways glycogen (starch) synthase activity ->
glycogen (starch) synthase activity INO4
|YNL015W| PBI2 regulation of proteolysis and peptidolysis, vacuole fusion (non-autophagic) ->
cell organization and biogenesis, catabolism, protein metabolism, regulation of metabolism endopeptidase inhibitor activity ->
endopeptidase inhibitor activity cytoplasm, vacuole (sensu Fungi) ->
cytoplasm, vacuole (sensu Fungi) INO4
YMR319C FET4 low affinity iron ion transport, intracellular copper ion transport ->
transport iron ion transporter activity ->
iron ion transporter activity integral to plasma membrane ->
integral to plasma membrane AZF1, CIN5, INO4, MAC1, NRG1, PHD1, RCS1, ROX1, SFL1, SOK2, YAP6
YDR141C DOP1 cellular morphogenesis ->
cell organization and biogenesis SFL1
Main: cell organization and biogenesis (0.67) RNA binding (0.20) cytoplasm (0.50) INO4 (0.60)
Score: 0.40 0.00 0.17 0.400
P-value: 1.057E+00 (development) 2.849E+00 (enzyme activity) 4.869E+00 (cytoplasm) 9.145E-03 (INO4)

m_OCSE15(1) AND SFF'(1) AND m_lipid_transporters_orfnum2SD_n8(1) => SimExpr(YKR093W) OR SimExpr(other) : 5 2

EXPR: (0.209) SFF' (P < 0.001) m_OCSE15 (P < 0.006) m_lipid_transporters_orfnum2SD_n8 (P < 0.005)

ORF SYMBOL P F C TF
|YDR091C| RLI1 ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity
YKR093W PTR2 peptide transport ->
transport peptide transporter activity ->
peptide transporter activity plasma membrane ->
plasma membrane CUP9, DAL81, FKH1, FKH2, HSF1, MET4, SKN7, SWI4
|YNL238W| KEX2 peptide pheromone maturation ->
protein metabolism serine-type endopeptidase activity ->
serine-type endopeptidase activity Golgi trans face ->
cytoplasm FKH2, MBP1, SKN7, SWI5, UGA3
YPL219W PCL8 regulation of glycogen catabolism, regulation of glycogen biosynthesis ->
carbohydrate metabolism, catabolism, biosynthesis, polysaccharide metabolism, energy pathways, regulation of metabolism cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex
YPR160W GPH1 glycogen catabolism ->
carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glycogen phosphorylase activity ->
glycogen phosphorylase activity cytoplasm ->
cytoplasm MAC1, MTH1, NDD1
YOR014W RTS1 protein biosynthesis, protein amino acid dephosphorylation ->
biosynthesis, phosphorus metabolism, protein metabolism protein phosphatase type 2A activity ->
protein phosphatase type 2A activity protein phosphatase type 2A complex, bud neck, nucleus, spindle pole body, cytoplasm ->
protein phosphatase type 2A complex, site of polarized growth (sensu Fungi), nucleus, cytoplasm
YLR170C APS1 vesicle-mediated transport ->
transport clathrin binding ->
clathrin binding AP-1 adaptor complex ->
cytoplasmic vesicle, cytoplasm DAL81, REB1
Main: biosynthesis (0.33) cyclin-dependent protein kinase\, regulator activity (0.14) cytoplasm (0.67) FKH2 SKN7 DAL81 (0.50)
Score: 0.27 0.00 0.40 0.333
P-value: 2.287E-03 (glycogen catabolism) 9.440E-01 (hydrolase activity) 1.089E-01 (Golgi apparatus) 8.596E-02 (DAL81)

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_MERE17(1) => SimExpr(YKR093W) OR SimExpr(other) : 6 2

EXPR: (0.225) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.012) m_MERE17 (P < 0.011)

ORF SYMBOL P F C TF
YOR347C PYK2 pyruvate metabolism, glycolysis ->
organic acid metabolism, alcohol metabolism, pyruvate dehydrogenase bypass, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism pyruvate kinase activity ->
phosphotransferase activity\, alcohol group as acceptor cytosol ->
cytoplasm ZMS1
YPR134W MSS18 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism MSS11
YKR093W PTR2 peptide transport ->
transport peptide transporter activity ->
peptide transporter activity plasma membrane ->
plasma membrane CUP9, DAL81, FKH1, FKH2, HSF1, MET4, SKN7, SWI4
|YMR199W| CLN1 regulation of CDK activity ->
cell proliferation cyclin-dependent protein kinase\, regulator activity ->
phosphotransferase activity\, alcohol group as acceptor, protein kinase regulator activity nucleus, cytoplasm ->
nucleus, cytoplasm FKH2, MBP1, NDD1, SKN7, STE12, SWI4, SWI6
YDR381W YRA1 mRNA-nucleus export ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding transcription export complex ->
nucleus ARO80
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
phosphoric ester hydrolase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
|YJL105W| SET4 ASH1, CIN5, FKH1, MTH1, PHD1, SKN7
YOR066W NO SYMBOL MBP1, MCM1
Main: carbohydrate metabolism (0.33) phosphotransferase activity\, alcohol group as acceptor (0.40) cytoplasm (0.40) SKN7 (0.43)
Score: 0.20 0.10 0.20 0.190
P-value: 6.137E-01 (carbohydrate metabolism) 5.562E-01 (phosphotransferase activity\, alcohol group as acceptor) 5.009E+00 (nucleus) 4.936E-02 (SKN7)

m_OCSE15(1) AND m_organization_of_chromosome_structure_orfnum2SD_n17(1) => SimExpr(YKR093W) OR SimExpr(other) : 6 1

m_other_transport_facilitators_orfnum2SD_n10(1) AND m_organization_of_chromosome_structure_orfnum2SD_n17(1) => SimExpr(YKR093W) OR SimExpr(other) : 5 1

EXPR: (0.198) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.005) m_other_transport_facilitators_orfnum2SD_n10 (P < 0.019)

ORF SYMBOL P F C TF
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid permease activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YOL012C HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
chromatin assembly complex, nuclear chromatin SWI4
|YPL230W| NO SYMBOL NRG1, SKN7
YKR093W PTR2 peptide transport ->
transport peptide transporter activity ->
peptide transporter activity plasma membrane ->
plasma membrane CUP9, DAL81, FKH1, FKH2, HSF1, MET4, SKN7, SWI4
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YOR051C NO SYMBOL PHD1, SFL1
Main: cell organization and biogenesis (0.50) amino acid permease activity (0.25) plasma membrane (0.67) SWI4 SKN7 (0.33)
Score: 0.33 0.00 0.33 0.133
P-value: 2.492E+00 (transport) 4.458E-01 (transporter activity) 2.623E-01 (plasma membrane) 2.819E-01 (SKN7)

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND m_cell_rescue_defense_cell_death_and_ageing_orfnum2SD_n20(1) => SimExpr(YKL163W) : 5

m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND HSE(1) => SimExpr(YOL049W) OR SimExpr(other) : 5 2

EXPR: (0.228) HSE (P < 0.006) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.005)

ORF SYMBOL P F C TF
YKL183W LOT5
YPL273W SAM4 sulfur amino acid metabolism ->
amine metabolism, sulfur metabolism, amino acid and derivative metabolism, organic acid metabolism homocysteine S-methyltransferase activity ->
homocysteine S-methyltransferase activity DAL81
YOL049W GSH2 glutathione biosynthesis ->
biosynthesis, coenzymes and prosthetic group metabolism, sulfur metabolism glutathione synthase activity ->
glutathione synthase activity intracellular ->
intracellular GCN4, SKN7
|YGR249W| MGA1 filamentous growth ->
cell organization and biogenesis ASH1, CIN5, CUP9, HSF1, IXR1, NRG1, PHD1, SKN7, SOK2, SWI4, YAP6
|YIL110W| NO SYMBOL SIP4
YNL070W TOM7 mitochondrial translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity intracellular ->
intracellular HAP4, STP2
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity intracellular ->
intracellular SMP1, SWI5
Main: cell organization and biogenesis (0.60) protein transporter activity (0.25) intracellular (1.00) SKN7 (0.33)
Score: 0.40 0.00 1.00 0.067
P-value: 3.730E-02 (sulfur metabolism) 2.849E+00 (enzyme activity) 3.997E+00 (intracellular) 4.622E-01 (SKN7)

m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) => SimExpr(YOL049W) OR SimExpr(other) : 5 2

EXPR: (0.195) m_allantoin_and_allantoate_transporters_orfnum2SD_n13 (P < 0.000) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.000) m_biogenesis_of_chromosome_structure_orfnum2SD_n9 (P < 0.001)

ORF SYMBOL P F C TF
|YKR004C| ECM9 cell wall organization and biogenesis ->
cell organization and biogenesis RTG3
YOL049W GSH2 glutathione biosynthesis ->
biosynthesis, coenzymes and prosthetic group metabolism, sulfur metabolism glutathione synthase activity ->
glutathione synthase activity intracellular ->
intracellular GCN4, SKN7
YMR145C NDE1 ethanol fermentation, NADH oxidation ->
alcohol metabolism, coenzymes and prosthetic group metabolism, energy pathways, vitamin metabolism NADH dehydrogenase activity ->
NADH dehydrogenase activity mitochondrion ->
intracellular SWI4
YNL252C MRPL17 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
intracellular
YOR198C BFR1 cytokinesis, spindle assembly, regulation of mitosis, bud growth, meiosis ->
cell organization and biogenesis, asexual reproduction, cell proliferation, mitotic cell cycle RNA binding ->
RNA binding polysome, nuclear envelope-endoplasmic reticulum network ->
endomembrane system, intracellular NDD1, REB1
YOR264W DSE3 SWI5
|YOR109W| INP53 endocytosis, dephosphorylation, cell wall organization and biogenesis ->
transport, phosphorus metabolism, cell organization and biogenesis inositol-1\,4\,5-trisphosphate 5-phosphatase activity ->
inositol-1\,4\,5-trisphosphate 5-phosphatase activity actin cortical patch (sensu Saccharomyces), membrane fraction ->
membrane fraction, intracellular SIP4
Main: cell organization and biogenesis (0.50) RNA binding (0.20) intracellular (1.00) SWI4 (0.17)
Score: 0.33 0.00 1.00 0.000
P-value: 1.157E-01 (coenzyme metabolism) 2.414E+00 (enzyme activity) 8.247E-01 (ribosome) 7.621E-01 (RTG3)

m_detoxificaton_orfnum2SD_n39(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YLR258W) : 6

EXPR: (0.191) m_detoxificaton_orfnum2SD_n39 (P < 0.003) m_anion_transporters_orfnum2SD_n20 (P < 0.003)

ORF SYMBOL P F C TF
YMR008C PLB1 glycerophospholipid metabolism ->
membrane lipid metabolism lysophospholipase activity ->
carboxylic ester hydrolase activity cell wall (sensu Fungi) ->
cell wall (sensu Fungi) RAP1
YNL241C ZWF1 pentose-phosphate shunt ->
alcohol catabolism, carbohydrate metabolism, coenzyme metabolism, monosaccharide metabolism, water-soluble vitamin metabolism, carbohydrate catabolism, energy derivation by oxidation of organic compounds glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YLR258W GSY2 glycogen metabolism ->
polysaccharide metabolism, energy derivation by oxidation of organic compounds glycogen (starch) synthase activity ->
transferase activity\, transferring hexosyl groups cytoplasm ->
cytoplasm
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cellular morphogenesis, sporulation (sensu Fungi), cell surface receptor linked signal transduction, intracellular signaling cascade RAS small monomeric GTPase activity ->
guanyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane ACE2, SKN7
YGR212W NO SYMBOL GCR2
YIL124W AYR1 phosphatidic acid biosynthesis ->
lipid biosynthesis, organic acid biosynthesis, membrane lipid metabolism, carboxylic acid metabolism acylglycerone-phosphate reductase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor endoplasmic reticulum, lipid particle, cytoplasm ->
endoplasmic reticulum, lipid particle, cytoplasm
Main: membrane lipid metabolism (0.40) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.40) cytoplasm (0.60) ACE2 SKN7 (0.50)
Score: 0.20 0.10 0.30 0.167
P-value: 1.219E-02 (glycerophospholipid metabolism) 5.374E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 3.918E+00 (cytoplasm) 3.954E-02 (ACE2)

m_detoxificaton_orfnum2SD_n39(1) AND m_MERE11(1) => SimExpr(YLR258W) : 5

EXPR: (0.188) m_MERE11 (P < 0.001) m_detoxificaton_orfnum2SD_n39 (P < 0.004)

m_g-proteins_orfnum2SD_n11(1) AND mRRPE(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YPR074C) OR SimExpr(other) : 7 3

EXPR: (0.205) m_g-proteins_orfnum2SD_n11 (P < 0.001) mRRPE (P < 0.000) m_amino-acid_transport_orfnum2SD_n18 (P < 0.000)

ORF SYMBOL P F C TF
YLR328W NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups CIN5, MSN1, ROX1
|YOL014W| NO SYMBOL
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YDR341C NO SYMBOL GCN4, ZMS1
|YGR280C| PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transferase activity\, transferring aldehyde or ketonic groups cytoplasm ->
cytoplasm REB1
YKR059W TIF1 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FKH1, FKH2
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
|YJR129C| NO SYMBOL DOT6, SIP4
Main: biosynthesis (0.57) translation factor activity\, nucleic acid binding (0.29) cytoplasm (0.80) ABF1 (0.14)
Score: 0.43 0.05 0.60 0.000
P-value: 7.863E-02 (pyridine nucleotide metabolism) 1.239E-01 (translation factor activity\, nucleic acid binding) 2.800E-01 (ribosome) 5.913E-01 (MSN1)

m_g-proteins_orfnum2SD_n11(1) AND LYS14(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YPR074C) OR SimExpr(other) : 6 2

EXPR: (0.194) m_g-proteins_orfnum2SD_n11 (P < 0.000) LYS14 (P < 0.000) m_amino-acid_transport_orfnum2SD_n18 (P < 0.002)

ORF SYMBOL P F C TF
YLR328W NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
nucleotidyltransferase activity CIN5, MSN1, ROX1
YGR060W ERG25 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid transporter activity, polyamine transporter activity, porter activity plasma membrane ->
plasma membrane SWI5
YOR346W REV1 DNA dependent DNA replication, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation DNA-directed DNA polymerase activity ->
nucleotidyltransferase activity nucleus ->
nucleus
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
|YGR280C| PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transketolase and transaldolase activity cytoplasm ->
cytoplasm REB1
|YJR129C| NO SYMBOL DOT6, SIP4
Main: cell organization and biogenesis (0.29) nucleotidyltransferase activity (0.29) cytoplasm (0.50) SWI5 (0.33)
Score: 0.24 0.05 0.33 0.067
P-value: 4.476E-02 (pyridine nucleotide metabolism) 5.062E-02 (nucleotidyltransferase activity) 7.201E-01 (plasma membrane) 1.624E-01 (SWI5)

Leu3(1) AND SCB(1) => SimExpr(YPR074C) OR SimExpr(other) : 6 2

m_other_transport_facilitators_orfnum2SD_n10(1) AND mRRPE(1) => SimExpr(YPR074C) : 5

EXPR: (0.151) mRRPE (P < 0.000) m_other_transport_facilitators_orfnum2SD_n10 (P < 0.002)

ORF SYMBOL P F C TF
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transketolase activity cytoplasm ->
cytoplasm REB1
YOR051C NO SYMBOL PHD1, SFL1
YPR041W TIF5 regulation of translational initiation, mature ribosome assembly ->
cell organization and biogenesis, biosynthesis, protein metabolism GTPase activator activity, translation initiation factor activity ->
GTPase activator activity, translation initiation factor activity cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
Main: cell organization and biogenesis (0.50) aconitate hydratase activity (0.25) cytoplasm (1.00) SFL1 (0.25)
Score: 0.50 0.00 1.00 0.000
P-value: 6.857E-02 (main pathways of carbohydrate metabolism) 5.735E-02 (enzyme regulator activity) 5.999E-01 (cytosol) 5.030E-01 (SFL1)

MCM1'(1) AND ALPHA1(1) AND SFF'(1) AND m_trna_processing_orfnum2SD_n9(1) => SimExpr(YNR028W) OR SimExpr(other) : 5 2

EXPR: (0.203) SFF' (P < 0.000) m_trna_processing_orfnum2SD_n9 (P < 0.001) ALPHA1 (P < 0.000) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YNR028W CPR8 peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity ASH1, DIG1, MCM1
YNL164C IBD2 mitotic spindle checkpoint ->
cell proliferation, cell cycle intracellular ->
intracellular
YGR017W NO SYMBOL GTS1
|YNL065W| AQR1 drug transport, monocarboxylic acid transport ->
transport, organic acid transport, response to abiotic stimulus monocarboxylic acid transporter activity, drug transporter activity ->
monocarboxylic acid transporter activity, drug transporter activity plasma membrane ->
plasma membrane MET4
|YNL287W| SEC21 ER to Golgi transport, retrograde (Golgi to ER) transport ->
transport, vesicle-mediated transport intracellular ->
intracellular ABF1
YIL118W RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
signal transduction, cell organization and biogenesis, transport Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YOL155C NO SYMBOL MAC1, MET4, PUT3, YAP6
Main: transport (0.75) peptidyl-prolyl cis-trans isomerase activity (0.33) intracellular (0.75) MET4 YAP6 (0.33)
Score: 0.50 0.00 0.50 0.133
P-value: 3.463E-01 (secretory pathway) 2.849E+00 (enzyme activity) 3.997E+00 (intracellular) 6.880E-02 (MET4)

MCM1'(1) AND ALPHA1(1) AND SFF(1) AND m_trna_processing_orfnum2SD_n9(1) => SimExpr(YNR028W) OR SimExpr(other) : 5 2

EXPR: (0.203) SFF (P < 0.001) m_trna_processing_orfnum2SD_n9 (P < 0.003) ALPHA1 (P < 0.000) MCM1' (P < 0.000)

m_fermentation_orfnum2SD_n3(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n18(1) => SimExpr(YGR036C) OR SimExpr(other) : 5 2

EXPR: (0.227) m_fermentation_orfnum2SD_n3 (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n18 (P < 0.000)

ORF SYMBOL P F C TF
YOL101C NO SYMBOL
YFL009W CDC4 ubiquitin-dependent protein catabolism, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle ->
catabolism, cell proliferation, protein metabolism ubiquitin-protein ligase activity, protein binding ->
ubiquitin-protein ligase activity, protein binding ubiquitin ligase complex, nucleus ->
ubiquitin ligase complex, nucleus PHO4
YGR036C CAX4 N-linked glycosylation, lipid biosynthesis ->
biosynthesis, protein modification, protein metabolism, lipid metabolism pyrophosphatase activity ->
pyrophosphatase activity endoplasmic reticulum membrane\, intrinsic protein ->
cytoplasm, endomembrane system
YIL120W QDR1 multidrug transport ->
transport, response to abiotic stimulus multidrug transporter activity ->
multidrug transporter activity plasma membrane, integral to plasma membrane ->
plasma membrane, integral to membrane PHD1, SIP4
|YFL057C| AAD16 aldehyde metabolism ->
aldehyde metabolism benzyl alcohol dehydrogenase activity ->
benzyl alcohol dehydrogenase activity ACE2, YAP1
YPL167C REV3 mutagenesis, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism zeta DNA polymerase activity ->
zeta DNA polymerase activity nucleus ->
nucleus
|YDL128W| VCX1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cytoplasm, vacuole MAC1, STE12
Main: transport (0.33) benzyl alcohol dehydrogenase activity (0.17) cytoplasm (0.40) ACE2 (0.25)
Score: 0.13 0.00 0.20 0.000
P-value: 3.490E+00 (transport) 7.707E-01 (transporter activity) 1.411E+00 (membrane) 6.668E-01 (ACE2)

m_pentose-phosphate_pathway_orfnum2SD_n14(1) AND m_g-proteins_orfnum2SD_n12(1) AND m_morphogenesis_orfnum2SD_n5(1) => SimExpr(YMR319C) OR SimExpr(other) : 6 1

m_metal_ion_transporters_orfnum2SD_n26(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YMR319C) OR SimExpr(other) : 5 1

EXPR: (0.195) m_metal_ion_transporters_orfnum2SD_n26 (P < 0.000) m_amino-acid_transport_orfnum2SD_n14 (P < 0.001)

ORF SYMBOL P F C TF
YKL160W ELF1 cell growth ->
cell growth
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to DNA damage, mitochondrion organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
|YIL164C| NIT1 MTH1
YHR063C PAN5 pantothenate biosynthesis ->
pantothenate biosynthesis gluconate 5-dehydrogenase activity ->
gluconate 5-dehydrogenase activity MBP1, SWI4
YLR211C NO SYMBOL HAP3
YMR319C FET4 low affinity iron ion transport, intracellular copper ion transport ->
low affinity iron ion transport, intracellular copper ion transport iron ion transporter activity ->
iron ion transporter activity integral to plasma membrane ->
integral to plasma membrane AZF1, CIN5, INO4, MAC1, NRG1, PHD1, RCS1, ROX1, SFL1, SOK2, YAP6
Main: cell growth (0.25) gluconate 5-dehydrogenase activity (0.33) integral to plasma membrane (1.00) HAP3 (0.20)
Score: 0.00 0.00 0.00 0.000
P-value: 3.529E+00 (cell growth and/or maintenance) 2.000E+00 0.000E+00 1.000E+00

SFF'(1) AND m_metal_ion_transporters_orfnum2SD_n17(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YMR319C) : 5

EXPR: (0.176) m_metal_ion_transporters_orfnum2SD_n17 (P < 0.000) SFF' (P < 0.001) m_amino-acid_transport_orfnum2SD_n14 (P < 0.000)

ORF SYMBOL P F C TF
YOR003W YSP3 protein catabolism ->
catabolism, protein metabolism peptidase activity ->
peptidase activity
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
phosphopyruvate hydratase complex, cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YOR385W NO SYMBOL
YMR319C FET4 low affinity iron ion transport, intracellular copper ion transport ->
transport iron ion transporter activity ->
iron ion transporter activity integral to plasma membrane ->
integral to plasma membrane AZF1, CIN5, INO4, MAC1, NRG1, PHD1, RCS1, ROX1, SFL1, SOK2, YAP6
Main: catabolism (0.50) phosphopyruvate hydratase activity (0.25) cytoplasm (0.50) AZF1 (0.33)
Score: 0.17 0.00 0.00 0.000
P-value: 4.285E-01 (catabolism) 2.509E+00 (enzyme activity) 3.000E+00 (cell) 1.000E+00

MCM1'(1) AND m_cellular_import_orfnum2SD_n12(1) => SimExpr(YDR353W) OR SimExpr(other) : 5 2

EXPR: (0.224) m_cellular_import_orfnum2SD_n12 (P < 0.047) MCM1' (P < 0.001)

ORF SYMBOL P F C TF
|YPL141C| NO SYMBOL FKH1, FKH2, NDD1
YDR353W TRR1 regulation of redox homeostasis ->
cell homeostasis oxidoreductase activity ->
oxidoreductase activity cytoplasm ->
cytoplasm
YIL069C RPS24B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, INO2, MCM1, RAP1
YML088W UFO1 response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity HAP4, RAP1, SKN7
|YOL151W| GRE2 response to stress ->
response to stress oxidoreductase activity ->
oxidoreductase activity nucleus, cytoplasm ->
nucleus, cytoplasm CIN5, MCM1, UGA3, USV1, YAP1, YAP6
YOR051C NO SYMBOL PHD1, SFL1
YOR130C ORT1 arginine biosynthesis, nuclear migration (sensu Saccharomyces) ->
amine metabolism, cell organization and biogenesis, cell proliferation, cell cycle, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ornithine transporter activity ->
ornithine transporter activity mitochondrial membrane ->
cytoplasm GCN4
Main: biosynthesis (0.40) oxidoreductase activity (0.40) cytoplasm (1.00) RAP1 MCM1 (0.33)
Score: 0.20 0.10 1.00 0.133
P-value: 4.671E-01 (response to stress) 3.837E-01 (oxidoreductase activity) 3.294E+00 (cytoplasm) 3.637E-01 (MCM1)

m_other_intracellular-transport_activities_orfnum2SD_n9(1) AND m_anion_transporters_orfnum2SD_n10(1) => SimExpr(YPL252C) OR SimExpr(other) : 5 2

EXPR: (0.221) m_anion_transporters_orfnum2SD_n10 (P < 0.003) m_other_intracellular-transport_activities_orfnum2SD_n9 (P < 0.013)

ORF SYMBOL P F C TF
|YIL033C| BCY1 response to stress, pseudohyphal growth, signal transduction, response to heat ->
response to stress, cell organization and biogenesis, signal transduction, response to abiotic stimulus cAMP-dependent protein kinase inhibitor activity ->
cAMP-dependent protein kinase inhibitor activity nucleus, cytoplasm ->
nucleus, cytoplasm
YNL052W COX5A aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
cytochrome c oxidase activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
YKR093W PTR2 peptide transport ->
transport peptide transporter activity ->
peptide transporter activity plasma membrane ->
plasma membrane CUP9, DAL81, FKH1, FKH2, HSF1, MET4, SKN7, SWI4
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YPL252C YAH1 heme a biosynthesis ->
pigment metabolism, coenzymes and prosthetic group biosynthesis, coenzymes and prosthetic group metabolism, biosynthesis, heterocycle metabolism electron carrier activity ->
electron carrier activity mitochondrial matrix ->
cytoplasm
|YIL115C| NUP159 mRNA-nucleus export, nuclear pore organization and biogenesis, ribosome nucleus export, rRNA-nucleus export ->
cell organization and biogenesis, intracellular transport, RNA localization, protein metabolism, transport structural molecule activity ->
structural molecule activity nuclear pore ->
nucleus, integral to membrane, endomembrane system SIP4
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
Main: cell organization and biogenesis (0.43) protein transporter activity (0.14) cytoplasm (0.71) SWI4 (0.20)
Score: 0.38 0.00 0.57 0.000
P-value: 8.303E-01 (protein targeting) 1.895E-02 (transporter activity) 4.732E-01 (membrane) 1.000E+00

m_other_energy_generation_activities_orfnum2SD_n22(1) AND m_RPE34(1) => SimExpr(YJL048C) OR SimExpr(other) : 5 2

EXPR: (0.218) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.003) m_RPE34 (P < 0.053)

m_metal_ion_transporters_orfnum2SD_n17(1) AND m_other_energy_generation_activities_orfnum2SD_n22(1) => SimExpr(YJL048C) OR SimExpr(other) : 5 2

EXPR: (0.193) m_metal_ion_transporters_orfnum2SD_n17 (P < 0.001) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.000)

m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6(1) AND m_other_cation_transporters_orfnum2SD_n3(1) => SimExpr(YJR025C) OR SimExpr(other) : 5 1

EXPR: (0.209) m_other_cation_transporters_orfnum2SD_n3 (P < 0.001) m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6 (P < 0.000)

ORF SYMBOL P F C TF
YGL006W PMC1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium-transporting ATPase activity ->
calcium-transporting ATPase activity vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole SKN7
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YML116W ATR1 multidrug transport ->
transport, response to abiotic stimulus multidrug efflux pump activity ->
multidrug efflux pump activity plasma membrane ->
plasma membrane CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YOR020C HSP10 protein folding ->
protein metabolism chaperone activity ->
chaperone activity mitochondrial matrix ->
cytoplasm ABF1
|YPR196W| NO SYMBOL
YJR025C BNA1 nicotinamide adenine dinucleotide biosynthesis ->
coenzymes and prosthetic group metabolism, biosynthesis, water-soluble vitamin metabolism, vitamin metabolism 3-hydroxyanthranilate 3\,4-dioxygenase activity ->
3-hydroxyanthranilate 3\,4-dioxygenase activity cytoplasm ->
cytoplasm GCN4, SUM1, SWI6
Main: transport (0.40) 3-hydroxyanthranilate 3\,4-dioxygenase activity (0.20) cytoplasm (0.80) ABF1 (0.20)
Score: 0.10 0.00 0.60 0.000
P-value: 2.492E+00 (transport) 3.603E-01 (oxidoreductase activity) 1.657E-01 (mitochondrial matrix) 9.267E-01 (IME4)

ALPHA1(1) AND m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_abc_transporters_orfnum2SD_n10(1) => SimExpr(YLR395C) OR SimExpr(other) : 5 2

MCM1'(1) AND m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND mRRPE(1) => SimExpr(YKR051W) OR SimExpr(other) : 5 2

EXPR: (0.233) mRRPE (P < 0.001) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.013) MCM1' (P < 0.003)

ORF SYMBOL P F C TF
YOL014W NO SYMBOL
|YNR060W| FRE4 iron-siderochrome transport ->
siderochrome transport ferric-chelate reductase activity ->
ferric-chelate reductase activity plasma membrane ->
plasma membrane NRG1
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to DNA damage, cytoplasm organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
|YGR159C| NSR1 ribosomal small subunit assembly and maintenance, rRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription single-stranded DNA binding, RNA binding ->
single-stranded DNA binding, RNA binding nucleolus, nucleus ->
nucleolus, nucleus
YOR051C NO SYMBOL PHD1, SFL1
YOR066W NO SYMBOL MBP1, MCM1
YKR051W NO SYMBOL
Main: cytoplasm organization and biogenesis (0.67) RNA binding (0.33) nucleolus (0.50) SFL1 (0.25)
Score: 0.33 0.00 0.00 0.000
P-value: 2.628E+00 (cytoplasm organization and biogenesis) 2.000E+00 3.000E+00 (cell) 6.955E-01 (SFL1)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) => SimExpr(YNL160W) OR SimExpr(other) : 6 2

m_RPE17(1) AND m_other_cation_transporters_orfnum2SD_n14(1) => SimExpr(YDL185W) OR SimExpr(other) : 5 2

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n10(1) AND m_anion_transporters_orfnum2SD_n19(1) => SimExpr(YGL157W) : 5

EXPR: (0.174) m_anion_transporters_orfnum2SD_n19 (P < 0.001) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.000) m_deoxyribonucleotide_metabolism_orfnum2SD_n10 (P < 0.000)

ORF SYMBOL P F C TF
YGR144W THI4 DNA repair, thiamin biosynthesis ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, vitamin metabolism mitochondrion ->
cytoplasm ABF1, CIN5
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YMR297W PRC1 vacuolar protein catabolism ->
catabolism, protein metabolism carboxypeptidase C activity ->
carboxypeptidase C activity cytoplasm, endoplasmic reticulum ->
cytoplasm ABF1
YGL157W NO SYMBOL CAD1, SIP4, SKO1
YIL009W FAA3 N-terminal protein myristoylation, lipid metabolism ->
biosynthesis, lipid metabolism, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
long-chain-fatty-acid-CoA-ligase activity MAL13, SKN7, SWI5, YAP6
Main: biosynthesis (0.75) long-chain-fatty-acid-CoA-ligase activity (0.33) cytoplasm (1.00) ABF1 (0.40)
Score: 0.67 0.00 1.00 0.100
P-value: 4.183E-01 (biosynthesis) 1.610E+00 (enzyme activity) 7.918E-01 (mitochondrion) 4.141E-01 (ABF1)

m_drug_transporters_orfnum2SD_n10(1) AND REB1(1) => SimExpr(YKL142W) OR SimExpr(other) : 5 2

EXPR: (0.211) m_drug_transporters_orfnum2SD_n10 (P < 0.000) REB1 (P < 0.006)

ORF SYMBOL P F C TF
YKL142W MRP8 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial ribosome ->
mitochondrial ribosome ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YMR186W HSC82 protein folding, response to stress ->
protein metabolism, response to stress cation-transporting ATPase activity, chaperone activity ->
cation-transporting ATPase activity, chaperone activity BAS1, HAP2, HSF1, INO4, REB1, ROX1
YMR002W NO SYMBOL NDD1, REB1, SWI6
|YGR218W| CRM1 ribosomal large subunit nucleus export, protein-nucleus export, mRNA-nucleus export ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transport protein carrier activity ->
protein carrier activity nucleus ->
nucleus ARG80, DIG1, GCN4, GCR2, LEU3, MCM1, NRG1, RCS1, RLM1, RTG3, STE12, STP1, SWI6, YJL206C
YGL248W PDE1 cAMP-mediated signaling ->
signal transduction cAMP-specific phosphodiesterase activity ->
cAMP-specific phosphodiesterase activity MSN2, MSN4
YNL185C MRPL19 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
mitochondrial ribosome, organellar large ribosomal subunit
|YMR013C| SEC59 protein-ER targeting, protein amino acid glycosylation ->
cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport dolichol kinase activity ->
dolichol kinase activity membrane ->
membrane FHL1, NDD1, RAP1, RLM1, RME1
Main: protein metabolism (0.83) structural constituent of ribosome (0.33) mitochondrial ribosome (0.50) REB1 (0.50)
Score: 0.67 0.07 0.17 0.400
P-value: 3.396E-01 (protein metabolism) 2.861E-01 (carrier activity) 7.847E-02 (mitochondrial ribosome) 5.420E-02 (REB1)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_organization_of_cell_wall_orfnum2SD_n14(1) => SimExpr(YKL121W) OR SimExpr(other) : 5 1

EXPR: (0.185) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.000) m_organization_of_cell_wall_orfnum2SD_n14 (P < 0.002)

ORF SYMBOL P F C TF
YOL152W FRE7 ferric-chelate reductase activity ->
ferric-chelate reductase activity MAC1
YKL121W NO SYMBOL REB1
YPL265W DIP5 amino acid transport ->
transport amino acid permease activity, amino acid transporter activity ->
amino acid permease activity, amino acid transporter activity plasma membrane ->
plasma membrane ARG80, ARG81, DAL81, PHD1, STP1
YIL048W NEO1 intracellular protein transport ->
transport calcium-transporting ATPase activity, phospholipid-translocating ATPase activity ->
calcium-transporting ATPase activity, phospholipid-translocating ATPase activity ABF1, GLN3, UGA3
|YOL104C| NDJ1 synapsis, telomere clustering ->
cell proliferation telomeric DNA binding ->
telomeric DNA binding nuclear chromosome\, telomeric region ->
nuclear chromosome\, telomeric region ABF1
YDR100W TVP15 RAP1
Main: transport (0.67) amino acid permease activity (0.25) nuclear chromosome\, telomeric region (0.50) ABF1 (0.33)
Score: 0.33 0.00 0.00 0.067
P-value: 2.136E+00 (transport) 1.400E-01 (carrier activity) 3.000E+00 (cell) 5.830E-01 (ARG81)

m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n20.scn(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YDR284C) OR SimExpr(other) : 5 1

EXPR: (0.162) m_amino-acid_transport_orfnum2SD_n14 (P < 0.000) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n20.scn (P < 0.001)

ORF SYMBOL P F C TF
YDR284C DPP1 phospholipid metabolism ->
lipid metabolism diacylglycerol pyrophosphate phosphatase activity, phosphatidate phosphatase activity ->
diacylglycerol pyrophosphate phosphatase activity, phosphatidate phosphatase activity vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole ABF1, FKH1, GCR2, GLN3, GTS1, RIM101, RTG1, SWI6
YDR462W MRPL28 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex ABF1
YDR380W ARO10 leucine catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism carboxy-lyase activity, pyruvate decarboxylase activity ->
carboxy-lyase activity, pyruvate decarboxylase activity ARO80, MTH1
YGR121C MEP1 ammonium transport ->
transport ammonium transporter activity ->
ammonium transporter activity plasma membrane ->
plasma membrane CIN5
YNL208W NO SYMBOL INO2
|YGR055W| MUP1 sulfur amino acid transport ->
transport L-methionine porter activity ->
L-methionine porter activity integral to plasma membrane ->
integral to membrane, plasma membrane DAL81, INO4, MET4, STP1
Main: transport (0.40) ammonium transporter activity (0.20) cytoplasm (0.50) ABF1 (0.33)
Score: 0.10 0.00 0.33 0.067
P-value: 2.492E+00 (transport) 5.944E-01 (transporter activity) 3.672E-01 (plasma membrane) 6.495E-01 (RIM101)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_other_transport_facilitators_orfnum2SD_n15(1) => SimExpr(YOR310C) OR SimExpr(other) : 6 2

EXPR: (0.223) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.006) m_other_transport_facilitators_orfnum2SD_n15 (P < 0.003)

ORF SYMBOL P F C TF
|YHL009C| YAP3 regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity ->
transcription factor activity nucleus ->
nucleus USV1
YKR091W SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm DIG1, RLM1, STE12
|YPR185W| APG13 protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
YNL157W NO SYMBOL
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
YLR185W RPL37A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1, RGM1, YAP5
YNL192W CHS1 budding ->
asexual reproduction chitin synthase activity ->
chitin synthase activity plasma membrane, chitosome ->
plasma membrane, cytoplasm STE12, SWI4, SWI5
YDR534C FIT1 siderochrome transport ->
transport cell wall (sensu Fungi) ->
cell wall PHO4
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.43) protein binding (0.25) cytoplasm (0.43) STE12 SWI6 (0.29)
Score: 0.29 0.00 0.24 0.095
P-value: 3.079E+00 (transcription\, DNA-dependent) 2.295E+00 (binding) 1.649E+00 (ribonucleoprotein complex) 2.102E-01 (STE12)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n13(1) => SimExpr(YNL180C) OR SimExpr(other) : 6 2

EXPR: (0.199) m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n13 (P < 0.005) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.000)

ORF SYMBOL P F C TF
YMR140W SIP5 cellular response to glucose starvation ->
response to extracellular stimulus, response to biotic stimulus cytoplasm ->
cytoplasm SKN7
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
YGR237C NO SYMBOL
YGR141W VPS62 protein-vacuolar targeting ->
cell organization and biogenesis, protein metabolism, transport
YNL180C RHO5 Rho protein signal transduction ->
signal transduction Rho small monomeric GTPase activity ->
GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides CIN5, YAP6
|YIR023W| DAL81 regulation of transcription from Pol II promoter, nitrogen utilization ->
nitrogen metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ABF1, YAP6
|YGR055W| MUP1 sulfur amino acid transport ->
transport L-methionine porter activity ->
amino acid-polyamine transporter activity, L-amino acid transporter activity, neutral amino acid transporter activity, sulfur amino acid transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane DAL81, INO4, MET4, STP1
YOR153W PDR5 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
ATP binding, multidrug transporter activity, P-P-bond-hydrolysis-driven transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane YAP6
Main: transport (0.43) hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides (0.40) plasma membrane (0.50) YAP6 (0.60)
Score: 0.24 0.10 0.17 0.300
P-value: 6.887E-01 (cell communication) 4.538E-01 (carrier activity) 5.401E-01 (plasma membrane) 1.663E-02 (YAP6)

m_g-proteins_orfnum2SD_n13(1) AND REB1(1) => SimExpr(YDR427W) OR SimExpr(other) : 6 3

m_other_protein-destination_activities_orfnum2SD_n7(1) AND RPN4(1) => SimExpr(YDR427W) OR SimExpr(other) : 6 3

EXPR: (0.247) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.001) RPN4 (P < 0.019)

ORF SYMBOL P F C TF
YKL210W UBA1 ubiquitin cycle ->
catabolism, protein metabolism ubiquitin activating enzyme activity ->
ubiquitin activating enzyme activity nucleus, cytoplasm ->
nucleus, cytoplasm SKO1
|YNL241C| ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YMR100W MUB1 regulation of budding ->
asexual reproduction
YDL126C CDC48 ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism ->
cell proliferation, cell death, macromolecule catabolism, transport, protein metabolism ATPase activity ->
ATPase activity nucleus, microsome, endoplasmic reticulum, cytosol ->
nucleus, membrane fraction, cytoplasm DAL82, MAL33, SWI4
|YGR235C| NO SYMBOL REB1
YIL075C RPN2 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism receptor activity, endopeptidase activity ->
receptor activity, endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus MSS11, REB1, SFL1
|YJR006W| HYS2 leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA repair, cell proliferation delta DNA polymerase activity ->
delta DNA polymerase activity delta DNA polymerase complex ->
cytoplasm, nucleus ABF1
YKL135C APL2 vesicle-mediated transport ->
transport clathrin binding ->
clathrin binding AP-1 adaptor complex ->
cytoplasmic vesicle, cytoplasm ABF1, DOT6
YDR427W RPN9 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome regulatory particle (sensu Eukarya), proteasome regulatory particle\, lid subcomplex (sensu Eukarya) ->
cytoplasm, nucleus ARG81, IXR1
Main: protein metabolism (0.50) endopeptidase activity (0.29) cytoplasm (1.00) ABF1 REB1 (0.25)
Score: 0.39 0.05 1.00 0.071
P-value: 1.294E-03 (ubiquitin-dependent protein catabolism) 4.736E-02 (endopeptidase activity) 1.095E-02 (proteasome regulatory particle (sensu Eukarya)) 1.000E+00

m_glyoxylate_cycle_orfnum2SD_n8(1) AND m_anion_transporters_orfnum2SD_n19(1) => SimExpr(YNL183C) OR SimExpr(other) : 6 3

EXPR: (0.239) m_anion_transporters_orfnum2SD_n19 (P < 0.018) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.034)

ORF SYMBOL P F C TF
YLR257W NO SYMBOL PHD1, SKN7
YKL197C PEX1 peroxisome organization and biogenesis ->
cell organization and biogenesis ATPase activity ->
ATPase activity MSS11, SIP4, SKO1, SOK2, ZMS1
|YDR293C| SSD1 cell wall organization and biogenesis ->
cell organization and biogenesis RNA binding ->
RNA binding cytoplasm ->
cytoplasm
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YNL183C NPR1 regulation of nitrogen utilization ->
nitrogen metabolism kinase activity ->
kinase activity cytoplasm ->
cytoplasm ABF1
|YIL066C| RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity cytoplasm ->
cytoplasm RFX1, STB1
YGR035C NO SYMBOL CIN5, MET4, SMP1, YAP6
YIL009W FAA3 N-terminal protein myristoylation, lipid metabolism ->
biosynthesis, lipid metabolism, protein metabolism long-chain-fatty-acid-CoA-ligase activity ->
long-chain-fatty-acid-CoA-ligase activity MAL13, SKN7, SWI5, YAP6
|YGL096W| TOS8 transcription factor activity ->
transcription factor activity IXR1, SOK2, SWI4
Main: cell organization and biogenesis (0.33) RNA binding (0.14) cytoplasm (1.00) SOK2 SKN7 MET4 YAP6 (0.25)
Score: 0.13 0.00 1.00 0.143
P-value: 4.866E+00 (biosynthesis) 8.927E-01 (oxidoreductase activity) 4.349E+00 (cytoplasm) 1.486E-01 (MET4)

ECB(1) AND m_phosphate_transport_orfnum2SD_n5(1) AND ALPHA1'(1) => SimExpr(YMR010W) OR SimExpr(other) : 5 2

EXPR: (0.208) ECB (P < 0.001) m_phosphate_transport_orfnum2SD_n5 (P < 0.000) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
|YMR122C| NO SYMBOL SWI5
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
macromolecule biosynthesis, monosaccharide metabolism, protein modification, nucleotide-sugar metabolism, glycoprotein metabolism, protein metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
YGR086C PIL1 ASH1, SWI5
YGR177C ATF2 steroid metabolism ->
steroid metabolism alcohol O-acetyltransferase activity ->
alcohol O-acetyltransferase activity cytoplasm ->
cytoplasm INO4, MCM1
YMR010W NO SYMBOL
YKL104C GFA1 cell wall chitin biosynthesis ->
external encapsulating structure organization and biogenesis, carbohydrate biosynthesis, biosynthesis, macromolecule biosynthesis, polysaccharide metabolism glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity ->
glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity REB1
|YLR272C| YCS4 mitotic chromosome condensation ->
cell cycle, mitotic cell cycle nuclear condensin complex ->
nuclear condensin complex
Main: macromolecule biosynthesis (0.50) glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity (0.33) cytoplasm (0.50) SWI5 (0.50)
Score: 0.17 0.00 0.00 0.167
P-value: 4.771E-01 (carbohydrate metabolism) 3.345E-01 (transferase activity) 4.000E+00 (intracellular) 5.152E-02 (SWI5)

m_metal_ion_transporters_orfnum2SD_n17(1) AND m_metal_ion_transporters_orfnum2SD_n6(1) => SimExpr(YFL041W) OR SimExpr(other) : 7 2

EXPR: (0.222) m_metal_ion_transporters_orfnum2SD_n17 (P < 0.002) m_metal_ion_transporters_orfnum2SD_n6 (P < 0.001)

SFF(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YJR148W) OR SimExpr(other) : 5 2

EXPR: (0.203) SFF (P < 0.000) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.001) m_amino-acid_transport_orfnum2SD_n14 (P < 0.000)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n7.scn(1) => SimExpr(YJR148W) OR SimExpr(other) : 7 2

EXPR: (0.228) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.004) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n7.scn (P < 0.003)

ORF SYMBOL P F C TF
YNL160W YGP1 response to stress, response to nutrients ->
response to stress, response to extracellular stimulus, response to abiotic stimulus cell wall (sensu Fungi) ->
cell wall
|YIL062C| ARC15 actin cortical patch assembly ->
cell organization and biogenesis structural molecule activity, actin binding ->
structural molecule activity, actin binding Arp2/3 protein complex, mitochondrial membrane ->
cytoplasm ADR1
|YHR132C| ECM14 cell wall organization and biogenesis ->
cell organization and biogenesis ARO80
YDR284C DPP1 phospholipid metabolism ->
lipid metabolism diacylglycerol pyrophosphate phosphatase activity, phosphatidate phosphatase activity ->
diacylglycerol pyrophosphate phosphatase activity, phosphatidate phosphatase activity vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole ABF1, FKH1, GCR2, GLN3, GTS1, RIM101, RTG1, SWI6
YFR053C HXK1 fructose metabolism ->
alcohol metabolism, carbohydrate metabolism hexokinase activity ->
hexokinase activity cytosol ->
cytoplasm
YGR192C TDH3 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity cytosol, lipid particle, cell wall, cytoplasm ->
cytoplasm, cell wall CIN5, GCR1, GCR2, GRF10(Pho2), HSF1, RAP1
YOR110W TFC7 transcription initiation from Pol III promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase III transcription factor activity ->
RNA polymerase III transcription factor activity transcription factor TFIIIC complex ->
nucleus GAT1, GCN4
YJR148W BAT2 branched chain family amino acid biosynthesis, amino acid catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis, catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity cytoplasm ->
cytoplasm NDD1, SKN7, SWI4
YJL052W TDH1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity cytosol, lipid particle, cell wall ->
cytoplasm, cell wall MAC1
Main: alcohol metabolism (0.33) glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity (0.29) cytoplasm (0.75) GCR2 (0.29)
Score: 0.17 0.05 0.61 0.048
P-value: 3.859E-02 (hexose metabolism) 1.131E-03 (glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity) 2.546E-02 (lipid particle) 2.872E-01 (GCR2)

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn(1) => SimExpr(YML058W) OR SimExpr(other) : 5 2

m_nitrogen_and_sulphur_metabolism_orfnum2SD_n29(1) AND m_g-proteins_orfnum2SD_n13(1) => SimExpr(YML058W) OR SimExpr(other) : 5 2

EXPR: (0.201) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n29 (P < 0.004) m_g-proteins_orfnum2SD_n13 (P < 0.000)

ORF SYMBOL P F C TF
|YOR031W| CRS5 response to metal ion ->
response to abiotic stimulus copper ion binding ->
copper ion binding cytoplasm ->
cytoplasm
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YDR077W SED1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi), ribosome ->
cell wall, cytoplasm, ribonucleoprotein complex CIN5, CUP9, DAL81, NRG1, RLM1, ROX1, SMP1, SOK2, YAP6
|YKR102W| FLO10 CIN5, CUP9, NRG1, PHD1, RLM1, ROX1, SFP1, SMP1, YAP6
YLR229C CDC42 exocytosis, apical bud growth, isotropic bud growth, pseudohyphal growth, invasive growth, Rho protein signal transduction, signal transduction during conjugation with cellular fusion, establishment of cell polarity (sensu Saccharomyces) ->
transport, asexual reproduction, cellular morphogenesis, signal transduction, conjugation with cellular fusion, cell organization and biogenesis, perception of external stimulus, vesicle-mediated transport, response to abiotic stimulus Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity soluble fraction, plasma membrane, bud tip, bud neck, shmoo tip ->
soluble fraction, plasma membrane, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces) ABF1, FZF1, INO2, RTS2
YOL038W PRE6 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
Main: cell organization and biogenesis (0.50) structural constituent of cell wall (0.17) cytoplasm (0.80) RLM1 YAP6 CIN5 ROX1 SMP1 CUP9 NRG1 (0.40)
Score: 0.33 0.00 0.60 0.100
P-value: 1.397E-01 (response to external stimulus) 6.743E-01 (hydrolase activity) 1.086E+00 (cytosol) 1.198E-01 (CUP9)

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND ECB(1) => SimExpr(YML058W) OR SimExpr(other) : 5 2

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YPR165W) OR SimExpr(other) : 7 2

EXPR: (0.214) m_cell_death_orfnum2SD_n8 (P < 0.003) m_other_pheromone_response_activities_orfnum2SD_n8 (P < 0.001)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_other_pheromone_response_activities_orfnum2SD_n8(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YPR165W) : 5

EXPR: (0.171) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.000) m_cell_death_orfnum2SD_n8 (P < 0.004) m_other_pheromone_response_activities_orfnum2SD_n8 (P < 0.001)

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND ALPHA1'(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YPR165W) : 5

EXPR: (0.159) m_cell_death_orfnum2SD_n8 (P < 0.000) m_other_pheromone_response_activities_orfnum2SD_n8 (P < 0.000) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
YMR142C RPL13B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, YAP5
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YPR165W RHO1 cell wall organization and biogenesis, bud growth, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
asexual reproduction, signal transduction, cell organization and biogenesis Rho small monomeric GTPase activity, signal transducer activity ->
small monomeric GTPase activity, signal transducer activity 1\,3-beta-glucan synthase complex, bud tip, bud neck, shmoo tip ->
plasma membrane, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces) ABF1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
Main: biosynthesis (0.60) small monomeric GTPase activity (0.40) cytoplasm (0.50) RAP1 MET4 (0.40)
Score: 0.40 0.10 0.33 0.200
P-value: 6.058E-02 (small GTPase mediated signal transduction) 2.267E-02 (small monomeric GTPase activity) 2.555E-01 (plasma membrane) 3.104E-02 (MET4)

m_amino-acid_transport_orfnum2SD_n14(1) AND Leu3(1) => SimExpr(YLR355C) OR SimExpr(other) : 5 1

EXPR: (0.191) Leu3 (P < 0.048) m_amino-acid_transport_orfnum2SD_n14 (P < 0.003)

ORF SYMBOL P F C TF
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrion ->
mitochondrion GCN4, MET4
|YDR043C| NRG1 response to pH, glucose metabolism, regulation of transcription from Pol II promoter, invasive growth ->
cell homeostasis, alcohol metabolism, cell organization and biogenesis, response to abiotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism transcriptional repressor activity, DNA binding ->
transcriptional repressor activity, DNA binding nucleus ->
nucleus NRG1, SKN7
YNL208W NO SYMBOL INO2
YOR271C NO SYMBOL LEU3, MAC1, MTH1
YHR063C PAN5 pantothenate biosynthesis ->
biosynthesis, coenzymes and prosthetic group metabolism gluconate 5-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor MBP1, SWI4
YMR086W NO SYMBOL FKH1
Main: cell organization and biogenesis (0.67) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.67) mitochondrion (0.50) SWI4 (0.17)
Score: 0.67 0.33 0.00 0.000
P-value: 3.051E+00 (biosynthesis) 4.606E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 3.999E+00 (intracellular) 7.179E-01 (LEU3)

m_anion_transporters_orfnum2SD_n20(1) AND m_rRSE10(1) => SimExpr(YOR110W) OR SimExpr(other) : 5 2

EXPR: (0.219) m_rRSE10 (P < 0.002) m_anion_transporters_orfnum2SD_n20 (P < 0.012)

ORF SYMBOL P F C TF
YNL052W COX5A aerobic respiration ->
energy derivation by oxidation of organic compounds cytochrome c oxidase activity ->
heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors, primary active transporter activity, cation transporter activity respiratory chain complex IV (sensu Eukarya) ->
mitochondrion, respiratory chain complex IV, inner membrane HAP4
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism isocitrate dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on CH-OH group of donors mitochondrial matrix, mitochondrion ->
mitochondrion MET4
|YOL068C| HST1 transcriptional gene silencing ->
gene silencing, transcription NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity ->
NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity histone deacetylase complex, nucleus ->
nucleoplasm, nucleus ABF1
YPR138C MEP3 ammonium transport ->
ion transport ammonium transporter activity ->
cation transporter activity plasma membrane ->
plasma membrane
YOR110W TFC7 transcription initiation from Pol III promoter ->
transcription RNA polymerase III transcription factor activity ->
RNA polymerase III transcription factor activity transcription factor TFIIIC complex ->
nucleoplasm GAT1, GCN4
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cellular morphogenesis, sporulation (sensu Fungi), cell surface receptor linked signal transduction, intracellular signaling cascade RAS small monomeric GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides plasma membrane ->
plasma membrane ACE2, SKN7
|YOR019W| NO SYMBOL CIN5
Main: energy derivation by oxidation of organic compounds (0.33) cation transporter activity (0.33) mitochondrion (0.33) ABF1 (0.17)
Score: 0.13 0.07 0.20 0.000
P-value: 4.648E-01 (energy pathways) 1.334E-01 (cation transporter activity) 1.818E-01 (transcription factor complex) 4.008E-01 (GAT1)

m_amino-acid_degradation_orfnum2SD_n8(1) AND m_g-proteins_orfnum2SD_n12(1) AND mRRPE(1) => SimExpr(YLR342W) OR SimExpr(other) : 5 2

EXPR: (0.233) mRRPE (P < 0.018) m_g-proteins_orfnum2SD_n12 (P < 0.004) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.004)

ORF SYMBOL P F C TF
YLR342W FKS1 beta-1\,3 glucan biosynthesis, cell wall organization and biogenesis ->
biosynthesis, cell organization and biogenesis, carbohydrate metabolism 1\,3-beta-glucan synthase activity ->
1\,3-beta-glucan synthase activity actin cap (sensu Saccharomyces), 1\,3-beta-glucan synthase complex ->
cell cortex, plasma membrane, cytoplasm MBP1, RLM1, STB1, SWI4
YJR016C ILV3 branched chain family amino acid biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis dihydroxy-acid dehydratase activity ->
dihydroxy-acid dehydratase activity mitochondrion ->
cytoplasm
YLR244C MAP1 proteolysis and peptidolysis ->
catabolism, protein metabolism methionyl aminopeptidase activity ->
methionyl aminopeptidase activity cytosolic ribosome (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
|YDR374C| NO SYMBOL RME1
YDR341C NO SYMBOL GCN4, ZMS1
YKL029C MAE1 pyruvate metabolism, amino acid metabolism ->
amine metabolism, organic acid metabolism, amino acid and derivative metabolism malate dehydrogenase (oxaloacetate decarboxylating) activity ->
malate dehydrogenase (oxaloacetate decarboxylating) activity mitochondrion ->
cytoplasm ABF1, CIN5
|YKL018W| SWD2 histone methylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism histone-lysine N-methyltransferase activity ->
histone-lysine N-methyltransferase activity nucleus ->
nucleus
Main: cell organization and biogenesis (0.40) dihydroxy-acid dehydratase activity (0.20) cytoplasm (0.80) ABF1 (0.25)
Score: 0.40 0.00 0.60 0.000
P-value: 4.170E-01 (amino acid metabolism) 1.037E+00 (enzyme activity) 1.397E+00 (mitochondrion) 4.249E-01 (ZMS1)

m_g-proteins_orfnum2SD_n13(1) AND REB1(1) => SimExpr(YOL148C) OR SimExpr(other) : 6 3

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_peroxisomal_transport_orfnum2SD_n19(1) => SimExpr(YAL060W) OR SimExpr(other) : 6 1

EXPR: (0.192) m_other_protein-destination_activities_orfnum2SD_n7 (P < 0.001) m_peroxisomal_transport_orfnum2SD_n19 (P < 0.005)

ORF SYMBOL P F C TF
YAL060W BDH1 butanediol fermentation ->
energy derivation by oxidation of organic compounds (R\,R)-butanediol dehydrogenase activity ->
(R\,R)-butanediol dehydrogenase activity cytoplasm ->
cytoplasm
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine biosynthesis, carboxylic acid metabolism, amine metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YNL208W NO SYMBOL INO2
|YMR170C| ALD2 beta-alanine biosynthesis, aldehyde metabolism, polyamine catabolism ->
amine biosynthesis, aldehyde metabolism, amine catabolism, amine metabolism, amino acid derivative catabolism, secondary metabolism, amino acid and derivative metabolism, carboxylic acid metabolism, amino acid derivative metabolism aldehyde dehydrogenase activity ->
aldehyde dehydrogenase activity cytoplasm ->
cytoplasm GRF10(Pho2)
YGR122W NO SYMBOL CIN5
YKL117W SBA1 protein folding ->
protein folding co-chaperone activity ->
co-chaperone activity nucleus, cytoplasm ->
nucleus, cytoplasm
YDL104C QRI7 CAD1, GTS1
Main: amino acid and derivative metabolism (0.50) aldehyde dehydrogenase activity (0.25) cytoplasm (1.00) CIN5 (0.40)
Score: 0.33 0.00 1.00 0.100
P-value: 2.105E-01 (amino acid biosynthesis) 3.837E-01 (oxidoreductase activity) 3.294E+00 (cytoplasm) 3.064E-01 (CIN5)

m_g-proteins_orfnum2SD_n11(1) AND m_peroxisomal_transport_orfnum2SD_n19(1) => SimExpr(YAL060W) OR SimExpr(other) : 7 1

m_c-compound_and_carbohydrate_utilization_orfnum2SD_n31(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YAL060W) : 5

EXPR: (0.168) m_cell_death_orfnum2SD_n16 (P < 0.000) m_c-compound_and_carbohydrate_utilization_orfnum2SD_n31 (P < 0.000)

ORF SYMBOL P F C TF
YNL241C ZWF1 pentose-phosphate shunt ->
alcohol catabolism, carbohydrate metabolism, coenzyme metabolism, monosaccharide metabolism, water-soluble vitamin metabolism, carbohydrate catabolism, energy derivation by oxidation of organic compounds glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YAL060W BDH1 butanediol fermentation ->
energy derivation by oxidation of organic compounds (R\,R)-butanediol dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm
YDR381W YRA1 mRNA-nucleus export ->
intracellular transport, RNA localization RNA binding ->
RNA binding transcription export complex ->
transcription export complex ARO80
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
phosphoric ester hydrolase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphate metabolism, macromolecule catabolism, protein modification, protein metabolism glycogen synthase kinase 3 activity ->
phosphotransferase activity\, alcohol group as acceptor MTH1
Main: response to stress (0.40) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.40) cytoplasm (0.50) ACE2 (0.33)
Score: 0.30 0.10 0.17 0.000
P-value: 1.930E-01 (energy pathways) 3.117E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 4.460E+00 (cytoplasm) 3.576E-01 (ADR1)

m_MERE4(1) AND m_RPE8(1) => SimExpr(YIL069C) OR SimExpr(other) : 5 2

SFF(1) AND m_amino-acid_transport_orfnum2SD_n3(1) AND m_amino-acid_transport_orfnum2SD_n13(1) => SimExpr(YPL265W) OR SimExpr(other) : 5 2

EXPR: (0.207) SFF (P < 0.000) m_amino-acid_transport_orfnum2SD_n13 (P < 0.002) m_amino-acid_transport_orfnum2SD_n3 (P < 0.000)

SFF'(1) AND m_amino-acid_transport_orfnum2SD_n13(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YPL265W) OR SimExpr(other) : 5 2

EXPR: (0.211) SFF' (P < 0.001) m_amino-acid_transport_orfnum2SD_n13 (P < 0.002) m_amino-acid_transport_orfnum2SD_n20 (P < 0.001)

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_organization_of_cell_wall_orfnum2SD_n14(1) => SimExpr(YPL265W) OR SimExpr(other) : 5 1

m_tricarboxylic-acid_pathway_orfnum2SD_n9(1) AND mRRPE(1) => SimExpr(YMR308C) OR SimExpr(other) : 5 1

m_LFTE17(1) AND HAP234(1) => SimExpr(YOR136W) : 5

EXPR: (0.168) m_LFTE17 (P < 0.001) HAP234 (P < 0.015)

ORF SYMBOL P F C TF
YNL052W COX5A aerobic respiration ->
energy derivation by oxidation of organic compounds cytochrome c oxidase activity ->
cytochrome c oxidase activity respiratory chain complex IV (sensu Eukarya) ->
mitochondrion, respiratory chain complex IV, inner membrane HAP4
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
mitochondrion MET4
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine biosynthesis, carboxylic acid metabolism, amine metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytosol, mitochondrion CIN5, YAP6
YGR008C STF2 response to dessication, ATP synthesis coupled proton transport ->
response to water, hydrogen transport, ion transport proton-transporting ATP synthase complex (sensu Eukarya) ->
mitochondrion, proton-transporting ATP synthase complex, proton-transporting two-sector ATPase complex, inner membrane INO2
YPL078C ATP4 ATP synthesis coupled proton transport ->
hydrogen transport, ion transport structural molecule activity ->
structural molecule activity proton-transporting ATP synthase\, stator stalk (sensu Eukarya) ->
mitochondrion, proton-transporting ATP synthase complex\, coupling factor F(o), proton-transporting ATP synthase complex, proton-transporting two-sector ATPase complex, inner membrane REB1, ZAP1
Main: energy derivation by oxidation of organic compounds (0.60) aconitate hydratase activity (0.25) mitochondrion (1.00) ZAP1 (0.20)
Score: 0.40 0.00 1.00 0.000
P-value: 2.642E-03 (glutamate biosynthesis) 2.022E-01 (oxidoreductase activity) 6.055E-04 (mitochondrion) 2.668E-01 (ZAP1)

m_amino-acid_transport_orfnum2SD_n14(1) AND m_other_cation_transporters_orfnum2SD_n18(1) => SimExpr(YIL075C) OR SimExpr(other) : 5 2

m_deoxyribonucleotide_metabolism_orfnum2SD_n8(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YIL075C) OR SimExpr(other) : 6 2

EXPR: (0.215) m_amino-acid_transport_orfnum2SD_n14 (P < 0.007) m_deoxyribonucleotide_metabolism_orfnum2SD_n8 (P < 0.004)

ORF SYMBOL P F C TF
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, membrane HAP4
YOL103W ITR2 myo-inositol transport ->
transport myo-inositol transporter activity ->
myo-inositol transporter activity membrane ->
membrane DIG1, MTH1
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
ketol-acid reductoisomerase activity mitochondrion ->
cytoplasm GCN4, MET4
YIL075C RPN2 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism receptor activity, endopeptidase activity ->
receptor activity, endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus MSS11, REB1, SFL1
|YJL128C| PBS2 activation of MAPK (osmolarity sensing), protein amino acid phosphorylation, osmosensory signaling pathway, actin filament organization ->
phosphorus metabolism, cell organization and biogenesis, signal transduction, protein modification, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism MAP kinase kinase activity, MAP-kinase scaffold protein activity ->
MAP kinase kinase activity, MAP-kinase scaffold protein activity cytoplasm ->
cytoplasm
YGR180C RNR4 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity nucleus, cytoplasm ->
nucleus, cytoplasm CIN5, MBP1, RAP1, RFX1, SWI6
|YOR349W| CIN1 post-chaperonin tubulin folding pathway, beta-tubulin folding ->
cell organization and biogenesis co-chaperone activity ->
co-chaperone activity microtubule ->
cytoplasm SWI5
Main: cell organization and biogenesis (0.38) phosphopyruvate hydratase activity (0.14) cytoplasm (0.88) SWI5 (0.29)
Score: 0.25 0.00 0.79 0.048
P-value: 1.218E+00 (organelle organization and biogenesis) 2.275E-01 (signal transducer activity) 7.307E-01 (cytoplasm) 2.436E-01 (SWI5)

ALPHA1(1) AND MCB(1) => SimExpr(YDL003W) OR SimExpr(other) : 23 9

Gcr1(1) AND m_other_cell_rescue_activities_orfnum2SD_n10(1) => SimExpr(YDR050C) OR SimExpr(other) : 5 1

EXPR: (0.167) m_other_cell_rescue_activities_orfnum2SD_n10 (P < 0.001) Gcr1 (P < 0.000)

ORF SYMBOL P F C TF
YMR143W RPS16A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome FHL1, GAT3, RAP1, RGM1, YAP5
YKL128C PMU1 INO4
YDR050C TPI1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism triose-phosphate isomerase activity ->
triose-phosphate isomerase activity cytosol, cytoplasm ->
cytosol, cytoplasm GCR1, GCR2, HSF1, INO4, SIG1
YJR009C TDH2 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity cytosol, lipid particle, cell wall, cytoplasm ->
cytosol, lipid particle, cell wall, cytoplasm CBF1, GCR1, GCR2
|YKL108W| SLD2 DNA strand elongation ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism replication fork ->
nucleoplasm PHD1
YKL060C FBA1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism fructose-bisphosphate aldolase activity ->
fructose-bisphosphate aldolase activity cytosol, cytoplasm ->
cytosol, cytoplasm ABF1, GCR2, GRF10(Pho2), INO4, MET4, RAP1
Main: biosynthesis (0.80) structural constituent of ribosome (0.25) cytosol (0.80) GCR2 INO4 (0.50)
Score: 0.60 0.00 0.60 0.400
P-value: 2.258E-04 (glycolysis) 2.077E+00 (enzyme activity) 1.155E-02 (cytosol) 2.368E-03 (GCR2)

m_glycolysis_and_gluconeogenesis_orfnum2SD_n4(1) AND ALPHA1(1) AND m_anion_transporters_orfnum2SD_n17(1) => SimExpr(YDR050C) OR SimExpr(other) : 5 2

EXPR: (0.181) m_glycolysis_and_gluconeogenesis_orfnum2SD_n4 (P < 0.000) ALPHA1 (P < 0.000) m_anion_transporters_orfnum2SD_n17 (P < 0.000)

ORF SYMBOL P F C TF
|YDR085C| AFR1 regulation of G-protein coupled receptor protein signaling pathway, signal transduction during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus receptor signaling protein activity ->
receptor signaling protein activity shmoo tip ->
site of polarized growth (sensu Fungi) FKH1, RLM1, SFL1
YDL130W RPP1B protein biosynthesis, translational elongation ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAL4, RAP1, RFX1
YKL178C STE3 signal transduction during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus mating-type a-factor pheromone receptor activity ->
mating-type a-factor pheromone receptor activity integral to plasma membrane ->
integral to membrane, plasma membrane SFP1, SUM1, YFL044C
YNL268W LYP1 basic amino acid transport ->
transport basic amino acid transporter activity ->
basic amino acid transporter activity plasma membrane ->
plasma membrane
YKL152C GPM1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphoglycerate mutase activity ->
phosphoglycerate mutase activity cytosol ->
cytoplasm GCR1, GCR2, HSF1, RAP1
YDR050C TPI1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism triose-phosphate isomerase activity ->
triose-phosphate isomerase activity cytosol, cytoplasm ->
cytoplasm GCR1, GCR2, HSF1, INO4, SIG1
|YHR198C| NO SYMBOL
Main: biosynthesis (0.50) structural constituent of ribosome (0.17) cytoplasm (0.50) GCR2 RAP1 HSF1 GCR1 (0.40)
Score: 0.27 0.00 0.27 0.200
P-value: 2.777E-02 (signal transduction during conjugation with cellular fusion) 2.225E-02 (isomerase activity) 2.775E-01 (cytosol) 4.546E-02 (GCR1)

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND LYS14(1) => SimExpr(YDL137W) OR SimExpr(other) : 5 2

EXPR: (0.206) LYS14 (P < 0.002) m_other_pheromone_response_activities_orfnum2SD_n8 (P < 0.018)

ORF SYMBOL P F C TF
YPL087W YDC1 ceramide metabolism, response to heat ->
lipid metabolism, response to abiotic stimulus ceramidase activity ->
ceramidase activity endoplasmic reticulum ->
cytoplasm
YIL075C RPN2 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism receptor activity, endopeptidase activity ->
signal transducer activity, endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus MSS11, REB1, SFL1
|YDR528W| HLR1 cell wall organization and biogenesis ->
cell organization and biogenesis MBP1, MCM1, SWI6
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transketolase activity cytoplasm ->
cytoplasm REB1
YPR165W RHO1 cell wall organization and biogenesis, bud growth, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
asexual reproduction, signal transduction, cell organization and biogenesis Rho small monomeric GTPase activity, signal transducer activity ->
small monomeric GTPase activity, signal transducer activity 1\,3-beta-glucan synthase complex, bud tip, bud neck, shmoo tip ->
plasma membrane, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces) ABF1
|YNR059W| MNT4 O-linked glycosylation ->
biosynthesis, protein metabolism alpha-1\,3-mannosyltransferase activity ->
alpha-1\,3-mannosyltransferase activity
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
small monomeric GTPase activity Golgi vesicle, cytosol ->
cytoplasm, Golgi apparatus MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: cell organization and biogenesis (0.29) signal transducer activity (0.33) cytoplasm (0.80) REB1 (0.60)
Score: 0.14 0.13 0.60 0.300
P-value: 3.276E-01 (external encapsulating structure organization and biogenesis) 5.404E-02 (small monomeric GTPase activity) 6.089E-01 (endoplasmic reticulum) 1.863E-02 (REB1)

m_g-proteins_orfnum2SD_n12(1) AND HAP234(1) => SimExpr(YDL137W) OR SimExpr(other) : 9 4

EXPR: (0.224) m_g-proteins_orfnum2SD_n12 (P < 0.000) HAP234 (P < 0.211)

ORF SYMBOL P F C TF
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
ligase activity\, forming carbon-nitrogen bonds DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YHL010C NO SYMBOL
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on CH-OH group of donors mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
carbon-oxygen lyase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YPR035W GLN1 nitrogen metabolism, glutamine biosynthesis ->
nitrogen metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis glutamate-ammonia ligase activity ->
ligase activity\, forming carbon-nitrogen bonds cytoplasm ->
cytoplasm CIN5, DAL81, FKH1, FKH2, GLN3, HSF1, INO4, MSN1, REB1, SWI4
|YKL198C| PTK1 polyamine transport ->
transport protein kinase activity ->
transferase activity\, transferring phosphorus-containing groups INO2
|YJL079C| PRY1 nuclear membrane, endoplasmic reticulum ->
nucleus, cytoplasm, endomembrane system NDD1, PHD1, RAP1
|YNL040W| NO SYMBOL FZF1, GCR2, RTG3, YAP7
YKL141W SDH3 oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways succinate dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-CH group of donors respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
|YGL067W| NPY1 NADH metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism NAD+ pyrophosphatase activity ->
hydrolase activity\, acting on acid anhydrides cytoplasm, peroxisome ->
cytoplasm STE12
YLR395C COX8 aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors, primary active transporter activity, cation transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
YDL140C RPO21 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase II\, core complex ->
nucleus REB1
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides Golgi vesicle, cytosol ->
cytoplasm, Golgi apparatus MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: biosynthesis (0.40) hydrolase activity\, acting on acid anhydrides (0.20) cytoplasm (0.89) REB1 (0.27)
Score: 0.27 0.07 0.81 0.127
P-value: 6.260E-04 (tricarboxylic acid cycle) 2.445E-01 (ligase activity\, forming carbon-nitrogen bonds) 4.198E-02 (mitochondrial electron transport chain) 3.396E-01 (REB1)

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YDL137W) OR SimExpr(other) : 7 2

m_MERE4(1) AND HAP234(1) => SimExpr(YDL137W) OR SimExpr(other) : 7 1

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YDL137W) OR SimExpr(other) : 6 2

EXPR: (0.207) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.005) m_other_morphogenetic_activities_orfnum2SD_n8 (P < 0.002)

ORF SYMBOL P F C TF
YNL059C ARP5 protein-vacuolar targeting ->
cell organization and biogenesis, protein metabolism, transport nucleus ->
nucleus ABF1, GRF10(Pho2)
YFR045W NO SYMBOL FKH1, PHO4, RIM101, UGA3, USV1
|YIR029W| DAL2 allantoin catabolism ->
amine metabolism, catabolism, heterocycle metabolism allantoicase activity ->
allantoicase activity
YCR023C NO SYMBOL YFL044C
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
ATP binding, multidrug transporter activity, P-P-bond-hydrolysis-driven transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane
|YOL159C| NO SYMBOL ARO80, CIN5, RLM1
YGL098W USE1 RCS1
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides Golgi vesicle, cytosol ->
Golgi vesicle, cytosol MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: transport (0.75) hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides (0.67) cytosol (0.33) ABF1 (0.17)
Score: 0.50 0.33 0.00 0.000
P-value: 1.626E+00 (intracellular transport) 9.861E-01 (hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides) 4.000E+00 (intracellular) 9.680E-01 (RIM101)

m_other_energy_generation_activities_orfnum2SD_n22(1) AND HAP234(1) => SimExpr(YDL137W) OR SimExpr(other) : 5 1

EXPR: (0.167) HAP234 (P < 0.016) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.000)

ORF SYMBOL P F C TF
YNL052W COX5A aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
cytochrome c oxidase activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane HAP4
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
|YJL079C| PRY1 nuclear membrane, endoplasmic reticulum ->
nucleus, cytoplasm, endomembrane system NDD1, PHD1, RAP1
YDL140C RPO21 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase II\, core complex ->
nucleus REB1
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
ARF small monomeric GTPase activity Golgi vesicle, cytosol ->
cytoplasm, Golgi apparatus MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: transport (0.40) ARF small monomeric GTPase activity (0.25) cytoplasm (0.83) REB1 HAP4 (0.33)
Score: 0.20 0.00 0.73 0.133
P-value: 2.804E-01 (energy pathways) 2.882E-01 (oxidoreductase activity) 2.361E-01 (mitochondrial inner membrane) 3.106E-02 (HAP4)

MCM1'(1) AND HAP234(1) => SimExpr(YDL137W) OR SimExpr(other) : 9 4

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_other_pheromone_response_activities_orfnum2SD_n8(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YDL137W) : 5

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_amino-acid_transport_orfnum2SD_n18(1) AND m_anion_transporters_orfnum2SD_n22(1) => SimExpr(YOL104C) OR SimExpr(other) : 6 2

EXPR: (0.222) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) m_amino-acid_transport_orfnum2SD_n18 (P < 0.000) m_anion_transporters_orfnum2SD_n22 (P < 0.000)

ORF SYMBOL P F C TF
YDR222W NO SYMBOL
YPL186C UIP4 nuclear membrane ->
nucleus, endomembrane system RIM101, USV1
|YNL241C| ZWF1 pentose-phosphate shunt ->
pentose-phosphate shunt glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YPR071W NO SYMBOL CRZ1
|YLR249W| YEF3 translational elongation ->
translational elongation translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YPR127W NO SYMBOL CIN5
YOL104C NDJ1 synapsis, telomere clustering ->
synapsis, telomere clustering telomeric DNA binding ->
DNA binding nuclear chromosome\, telomeric region ->
chromosome, nucleus ABF1
YGR258C RAD2 nucleotide-excision repair\, DNA incision\, 3' to lesion ->
nucleotide-excision repair\, DNA incision\, 3' to lesion single-stranded DNA specific endodeoxyribonuclease activity ->
DNA binding, hydrolase activity\, acting on ester bonds nucleotide excision repair factor 3 complex ->
nucleus RAP1, SUM1
Main: nucleotide-excision repair\, DNA incision\, 3' to lesion (0.25) DNA binding (0.50) nucleus (0.60) ABF1 (0.14)
Score: 0.00 0.17 0.40 0.000
P-value: 3.939E+00 (metabolism) 6.105E-01 (DNA binding) 3.467E+00 (nucleus) 8.521E-01 (ADR1)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND SFF'(1) AND m_amino-acid_transport_orfnum2SD_n18(1) AND m_anion_transporters_orfnum2SD_n22(1) => SimExpr(YOL104C) OR SimExpr(other) : 5 1

EXPR: (0.197) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) SFF' (P < 0.000) m_amino-acid_transport_orfnum2SD_n18 (P < 0.000) m_anion_transporters_orfnum2SD_n22 (P < 0.000)

ORF SYMBOL P F C TF
YDR222W NO SYMBOL
YPL186C UIP4 nuclear membrane ->
nucleus, endomembrane system RIM101, USV1
YPR071W NO SYMBOL CRZ1
|YLR249W| YEF3 translational elongation ->
translational elongation translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YPR127W NO SYMBOL CIN5
YOL104C NDJ1 synapsis, telomere clustering ->
synapsis, telomere clustering telomeric DNA binding ->
telomeric DNA binding nuclear chromosome\, telomeric region ->
chromosome, nucleus ABF1
Main: translational elongation (0.50) translation elongation factor activity (0.50) nucleus (0.67) ABF1 (0.20)
Score: 0.00 0.00 0.33 0.000
P-value: 3.000E+00 (physiological processes) 1.103E+00 (nucleic acid binding) 3.428E+00 (nucleus) 2.842E-01 (RIM101)

m_phosphate_utilization_orfnum2SD_n9(1) AND m_meiosis_orfnum2SD_n3(1) => SimExpr(YOL104C) : 5

EXPR: (0.137) m_phosphate_utilization_orfnum2SD_n9 (P < 0.000) m_meiosis_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
YIL072W HOP1 meiosis, synaptonemal complex formation ->
meiosis, synapsis DNA binding ->
DNA binding condensed nuclear chromosome, synaptonemal complex ->
condensed chromosome, nuclear chromosome
YJL045W NO SYMBOL MBP1, ROX1
YKR005C NO SYMBOL
YOL104C NDJ1 synapsis, telomere clustering ->
synapsis, telomere clustering telomeric DNA binding ->
DNA binding nuclear chromosome\, telomeric region ->
chromosome\, telomeric region, nuclear chromosome ABF1
YOR338W NO SYMBOL RAP1
Main: synapsis (1.00) DNA binding (1.00) nuclear chromosome (1.00) ABF1 (0.33)
Score: 1.00 1.00 1.00 0.000
P-value: 6.943E-04 (synapsis) 2.082E-01 (DNA binding) 8.511E-02 (chromosome) 4.434E-01 (ROX1)

SFF(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n18(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YKL210W) OR SimExpr(other) : 5 2

EXPR: (0.227) SFF (P < 0.000) m_amino-acid_transport_orfnum2SD_n20 (P < 0.010) m_allantoin_and_allantoate_transporters_orfnum2SD_n18 (P < 0.006)

ORF SYMBOL P F C TF
YKL210W UBA1 ubiquitin cycle ->
catabolism, protein metabolism ubiquitin activating enzyme activity ->
ubiquitin activating enzyme activity nucleus, cytoplasm ->
nucleus, cytoplasm SKO1
|YFL009W| CDC4 ubiquitin-dependent protein catabolism, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle ->
catabolism, cell proliferation, protein metabolism ubiquitin-protein ligase activity, protein binding ->
ubiquitin-protein ligase activity, protein binding ubiquitin ligase complex, nucleus ->
ubiquitin ligase complex, nucleus PHO4
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid permease activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YOL086C ADH1 fermentation ->
energy pathways alcohol dehydrogenase activity ->
alcohol dehydrogenase activity cytosol ->
cytoplasm GCR1, GCR2, GTS1, RAP1
|YPL219W| PCL8 regulation of glycogen catabolism, regulation of glycogen biosynthesis ->
carbohydrate metabolism, catabolism, biosynthesis, polysaccharide metabolism, energy pathways, regulation of metabolism cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex
YOR187W TUF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity mitochondrial matrix, mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex HAP4, REB1
YGL009C LEU1 leucine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis 3-isopropylmalate dehydratase activity ->
3-isopropylmalate dehydratase activity cytosol ->
cytoplasm LEU3
Main: biosynthesis (0.43) 3-isopropylmalate dehydratase activity (0.14) cytoplasm (0.57) GCR2 (0.17)
Score: 0.43 0.00 0.33 0.000
P-value: 2.621E-01 (ubiquitin-dependent protein catabolism) 1.037E+00 (enzyme activity) 1.267E+00 (cytosol) 6.725E-01 (SKO1)

m_allantoin_and_allantoate_transporters_orfnum2SD_n18(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YKL210W) OR SimExpr(other) : 5 2

m_other_protein-destination_activities_orfnum2SD_n7(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) => SimExpr(YKL210W) OR SimExpr(other) : 6 2

m_stress_response_orfnum2SD_n4(1) AND m_cell_rescue_defense_cell_death_and_ageing_orfnum2SD_n20(1) => SimExpr(YLR327C) OR SimExpr(other) : 5 2

EXPR: (0.214) m_stress_response_orfnum2SD_n4 (P < 0.002) m_cell_rescue_defense_cell_death_and_ageing_orfnum2SD_n20 (P < 0.005)

ORF SYMBOL P F C TF
|YKL142W| MRP8 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YGR088W CTT1 response to stress ->
response to stress catalase activity ->
catalase activity cytoplasm ->
cytoplasm
YGR192C TDH3 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity cytosol, lipid particle, cell wall, cytoplasm ->
cytoplasm, cell wall CIN5, GCR1, GCR2, GRF10(Pho2), HSF1, RAP1
|YPL143W| RPL33A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MET4, NDD1, PDR1, RAP1, RME1
YLR327C NO SYMBOL HSF1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
Main: biosynthesis (0.50) structural constituent of ribosome (0.33) cytoplasm (0.83) ACE2 SKN7 (0.50)
Score: 0.27 0.07 0.67 0.467
P-value: 5.042E-02 (hexose catabolism) 7.452E-02 (oxidoreductase activity) 8.247E-01 (ribosome) 2.102E-03 (ACE2)

ALPHA1'(1) AND m_amino-acid_transport_orfnum2SD_n14(1) AND m_rRSE10(1) => SimExpr(YMR302C) OR SimExpr(other) : 5 2

EXPR: (0.190) m_rRSE10 (P < 0.000) m_amino-acid_transport_orfnum2SD_n14 (P < 0.000) ALPHA1' (P < 0.000)

ALPHA1(1) AND m_amino-acid_transport_orfnum2SD_n14(1) AND m_rRSE10(1) => SimExpr(YMR302C) : 5

EXPR: (0.143) m_rRSE10 (P < 0.000) m_amino-acid_transport_orfnum2SD_n14 (P < 0.000) ALPHA1 (P < 0.000)

m_glyoxylate_cycle_orfnum2SD_n11(1) AND m_MERE11(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YJL036W) OR SimExpr(other) : 5 2

EXPR: (0.214) m_MERE11 (P < 0.002) m_cell_death_orfnum2SD_n16 (P < 0.000) m_glyoxylate_cycle_orfnum2SD_n11 (P < 0.000)

RAP1(1) AND m_peroxisomal_organization_orfnum2SD_n28(1) => SimExpr(YMR194W) OR SimExpr(other) : 5 2

RAP1(1) AND m_pentose-phosphate_pathway_orfnum2SD_n5(1) => SimExpr(YMR194W) OR SimExpr(other) : 5 2

RAP1(1) AND m_morphogenesis_orfnum2SD_n5(1) => SimExpr(YMR194W) OR SimExpr(other) : 5 2

m_glycolysis_and_gluconeogenesis_orfnum2SD_n4(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) => SimExpr(YMR194W) OR SimExpr(other) : 5 1

RAP1(1) AND m_RPE34(1) => SimExpr(YMR194W) : 8

m_glycolysis_and_gluconeogenesis_orfnum2SD_n4(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) AND SFF'(1) => SimExpr(YMR194W) : 5

EXPR: (0.147) SFF' (P < 0.000) m_glycolysis_and_gluconeogenesis_orfnum2SD_n4 (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n6 (P < 0.000)

m_glyoxylate_cycle_orfnum2SD_n7(1) AND SWI5(1) AND CSRE(1) => SimExpr(YOR312C) OR SimExpr(other) : 8 3

EXPR: (0.217) SWI5 (P < 0.000) CSRE (P < 0.003) m_glyoxylate_cycle_orfnum2SD_n7 (P < 0.002)

ORF SYMBOL P F C TF
|YNL019C| NO SYMBOL
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YGL038C OCH1 N-linked glycoprotein maturation ->
biosynthesis, protein metabolism transferase activity\, transferring glycosyl groups, alpha-1\,6-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups, alpha-1\,6-mannosyltransferase activity Golgi cis cisterna ->
cytoplasm CRZ1, SKN7, SWI4, SWI6
YMR002W NO SYMBOL NDD1, REB1, SWI6
YOR312C RPL20B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, FKH2, GAT3, RAP1
|YMR291W| NO SYMBOL RAP1
YJL158C CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YDR309C GIC2 axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) ->
asexual reproduction, signal transduction, cell organization and biogenesis signal transducer activity ->
signal transducer activity actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site ->
cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6
|YJR116W| NO SYMBOL ABF1
YLR229C CDC42 exocytosis, apical bud growth, isotropic bud growth, pseudohyphal growth, invasive growth, Rho protein signal transduction, signal transduction during conjugation with cellular fusion, establishment of cell polarity (sensu Saccharomyces) ->
transport, asexual reproduction, cellular morphogenesis, signal transduction, conjugation with cellular fusion, cell organization and biogenesis, perception of external stimulus, vesicle-mediated transport, response to abiotic stimulus Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity soluble fraction, plasma membrane, bud tip, bud neck, shmoo tip ->
soluble fraction, plasma membrane, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces) ABF1, FZF1, INO2, RTS2
YPL260W NO SYMBOL SUM1
Main: cell organization and biogenesis (0.50) signal transducer activity (0.33) cytoplasm (0.80) SWI6 (0.40)
Score: 0.40 0.07 0.80 0.267
P-value: 5.767E-02 (Rho protein signal transduction) 4.105E-01 (signal transducer activity) 2.472E-03 (bud tip) 6.139E-03 (SWI6)

m_RPE6(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YOR312C) : 7

m_RPE57(1) AND m_RPE6(1) => SimExpr(YOR312C) : 7

RAP1(1) AND m_RPE6(1) => SimExpr(YOR312C) : 9

RAP1(1) AND m_metabolism_of_energy_reserves_orfnum2SD_n8(1) => SimExpr(YOR312C) : 5

RAP1(1) AND m_RPE57(1) => SimExpr(YOR312C) : 8

RAP1(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YOR312C) : 8

RAP1(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YMR142C) OR SimExpr(other) : 7 3

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YMR142C) OR SimExpr(other) : 7 2

RAP1(1) AND m_g-proteins_orfnum2SD_n13(1) => SimExpr(YMR142C) OR SimExpr(other) : 5 1

m_RPE68(1) AND m_anion_transporters_orfnum2SD_n4(1) => SimExpr(YMR142C) OR SimExpr(other) : 5 1

EXPR: (0.176) m_RPE68 (P < 0.005) m_anion_transporters_orfnum2SD_n4 (P < 0.001)

ORF SYMBOL P F C TF
YMR142C RPL13B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
intracellular FHL1, GAT3, RAP1, RGM1, YAP5
|YNL241C| ZWF1 pentose-phosphate shunt ->
pentose-phosphate shunt glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
intracellular ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YAL022C FUN26 nucleoside transport ->
nucleoside transport nucleoside transporter activity ->
nucleoside transporter activity intracellular, membrane ->
intracellular, membrane ADR1, FHL1, FZF1, IME4, MAC1, MATa1, NRG1, PDR1, SFP1, SMP1, STB1, SWI5, YFL044C
YPL143W RPL33A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
intracellular FHL1, MET4, NDD1, PDR1, RAP1, RME1
YGL215W CLG1 cell cycle ->
cell cycle cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity cyclin-dependent protein kinase holoenzyme complex ->
intracellular
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
membrane ACE2, SKN7
Main: protein biosynthesis (0.33) structural constituent of ribosome (0.33) intracellular (0.83) FHL1 (0.60)
Score: 0.07 0.07 0.73 0.600
P-value: 1.478E+00 (protein biosynthesis) 2.466E-01 (structural constituent of ribosome) 9.330E-02 (cytosolic large ribosomal subunit (sensu Eukarya)) 9.764E-03 (ADR1)

RAP1(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YMR142C) : 8

RAP1(1) AND m_RPE69(1) => SimExpr(YMR142C) : 6

RAP1(1) AND m_RPE57(1) => SimExpr(YMR142C) : 8

RAP1(1) AND m_pentose-phosphate_pathway_orfnum2SD_n5(1) => SimExpr(YMR230W) OR SimExpr(other) : 6 1

RAP1(1) AND m_morphogenesis_orfnum2SD_n5(1) => SimExpr(YMR230W) OR SimExpr(other) : 5 2

RAP1(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YMR230W) OR SimExpr(other) : 8 3

RAP1(1) AND MCM1'(1) => SimExpr(YMR230W) OR SimExpr(other) : 18 2

RAP1(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) => SimExpr(YGL076C) OR SimExpr(other) : 5 2

RAP1(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) => SimExpr(YGL076C) OR SimExpr(other) : 5 2

RAP1(1) AND m_trna_processing_orfnum2SD_n6(1) => SimExpr(YGL076C) OR SimExpr(other) : 5 2

RAP1(1) AND CSRE(1) => SimExpr(YDR450W) OR SimExpr(other) : 12 2

m_RPE6(1) AND CSRE(1) => SimExpr(YDR450W) OR SimExpr(other) : 10 1

RAP1(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YDR450W) OR SimExpr(other) : 8 3

m_amino-acid_transport_orfnum2SD_n3(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) => SimExpr(YDR450W) OR SimExpr(other) : 5 1

EXPR: (0.200) m_tricarboxylic-acid_pathway_orfnum2SD_n3 (P < 0.024) m_amino-acid_transport_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
YPL250C ICY2 HSF1, MET4
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
|YOR161C| NO SYMBOL FHL1, PHD1, RAP1
YGR086C PIL1 ASH1, SWI5
YDR450W RPS18A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
Main: biosynthesis (1.00) structural constituent of ribosome (0.33) cytoplasm (1.00) RAP1 MET4 FHL1 (0.40)
Score: 1.00 0.00 1.00 0.200
P-value: 5.883E-01 (biosynthesis) 2.725E+00 (enzyme activity) 4.731E+00 (cytoplasm) 3.900E-02 (MET4)

m_LFTE17(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) => SimExpr(YDR450W) OR SimExpr(other) : 6 2

RAP1(1) AND MCM1'(1) => SimExpr(YDR450W) OR SimExpr(other) : 18 2

m_other_mrna-transcription_activities_orfnum2SD_n20(1) AND m_c-compound_carbohydrate_transport_orfnum2SD_n23(1) => SimExpr(YDR450W) OR SimExpr(other) : 5 1

EXPR: (0.185) m_other_mrna-transcription_activities_orfnum2SD_n20 (P < 0.002) m_c-compound_carbohydrate_transport_orfnum2SD_n23 (P < 0.020)

ORF SYMBOL P F C TF
|YDL020C| RPN4 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus ABF1, CBF1, HSF1, PUT3, YAP1
YML073C RPL6A protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, YAP5
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YOL148C SPT20 chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription cofactor activity ->
transcription cofactor activity SAGA complex ->
nucleus GRF10(Pho2), MATa1, MIG1, PHO4
YML088W UFO1 response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity HAP4, RAP1, SKN7
YDR450W RPS18A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
Main: protein metabolism (0.83) structural constituent of ribosome (0.33) cytoplasm (0.80) RAP1 (0.50)
Score: 0.80 0.07 0.70 0.200
P-value: 1.255E-01 (protein metabolism) 2.959E-01 (structural constituent of ribosome) 2.158E-01 (cytosol) 6.729E-02 (YAP5)

RAP1(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) => SimExpr(YDR450W) OR SimExpr(other) : 6 1

RAP1(1) AND m_other_mrna-transcription_activities_orfnum2SD_n20(1) => SimExpr(YDR450W) OR SimExpr(other) : 8 2

RAP1(1) AND m_pentose-phosphate_pathway_orfnum2SD_n5(1) => SimExpr(YDR450W) OR SimExpr(other) : 6 1

RAP1(1) AND m_RPE34(1) => SimExpr(YDR450W) : 8

RAP1(1) AND m_LFTE17(1) => SimExpr(YDR450W) : 7

CSRE(1) AND m_c-compound_carbohydrate_transport_orfnum2SD_n23(1) => SimExpr(YDR450W) : 5

m_pentose-phosphate_pathway_orfnum2SD_n5(1) AND m_RPE6(1) => SimExpr(YDR450W) : 6

RAP1(1) AND m_RPE6(1) => SimExpr(YDR450W) : 9

m_RPE6(1) AND m_RPE34(1) => SimExpr(YDR450W) : 6

RAP1(1) AND mRRPE(1) => SimExpr(YMR116C) OR SimExpr(other) : 7 3

RAP1(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YMR116C) OR SimExpr(other) : 7 3

RAP1(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) => SimExpr(YOR369C) OR SimExpr(other) : 5 2

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YOR369C) : 5

EXPR: (0.119) SWI5 (P < 0.000) RAP1 (P < 0.036) SCB (P < 0.000)

ORF SYMBOL P F C TF
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity ribosome ->
ribosome INO2, INO4
YMR194W RPL36A protein biosynthesis ->
protein biosynthesis RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
YLR344W RPL26A protein biosynthesis ->
protein biosynthesis RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, RAP1
YPR080W TEF1 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity ribosome ->
ribosome FHL1, PDR1, RAP1, YAP5
YOR369C RPS12 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
Main: protein biosynthesis (1.00) structural constituent of ribosome (0.60) ribosome (1.00) FHL1 (0.80)
Score: 1.00 0.40 1.00 0.600
P-value: 1.836E-04 (protein biosynthesis) 1.741E-03 (translation elongation factor activity) 3.393E-05 (ribosome) 9.347E-05 (FHL1)

RAP1(1) AND mRRPE(1) => SimExpr(YDL130W) OR SimExpr(other) : 7 3

RAP1(1) AND m_nitrogen_and_sulphur_transport_orfnum2SD_n9(1) => SimExpr(YDL130W) OR SimExpr(other) : 7 2

RAP1(1) AND MCM1'(1) => SimExpr(YDL130W) OR SimExpr(other) : 18 2

RAP1(1) AND m_glycolysis_and_gluconeogenesis_orfnum2SD_n4(1) => SimExpr(YDL130W) : 5

RAP1(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) => SimExpr(YPL131W) OR SimExpr(other) : 5 2

m_RPE6(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YGL030W) OR SimExpr(other) : 8 2

m_other_mrna-transcription_activities_orfnum2SD_n20(1) AND m_RPE6(1) => SimExpr(YGL030W) OR SimExpr(other) : 7 1

EXPR: (0.141) m_other_mrna-transcription_activities_orfnum2SD_n20 (P < 0.000) m_RPE6 (P < 0.033)

RAP1(1) AND m_drug_transporters_orfnum2SD_n10(1) => SimExpr(YGL030W) OR SimExpr(other) : 6 2

RAP1(1) AND m_other_mrna-transcription_activities_orfnum2SD_n20(1) => SimExpr(YGL030W) OR SimExpr(other) : 8 2

RAP1(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YGL030W) OR SimExpr(other) : 8 3

RAP1(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n4(1) => SimExpr(YGL030W) OR SimExpr(other) : 5 2

EXPR: (0.177) m_deoxyribonucleotide_metabolism_orfnum2SD_n4 (P < 0.001) RAP1 (P < 0.102)

m_RPE6(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) => SimExpr(YGL030W) OR SimExpr(other) : 5 2

EXPR: (0.190) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.000) m_RPE6 (P < 0.391)

RAP1(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) => SimExpr(YGL030W) OR SimExpr(other) : 6 1

RAP1(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YGL030W) OR SimExpr(other) : 8 2

RAP1(1) AND MCM1'(1) => SimExpr(YGL030W) OR SimExpr(other) : 18 2

RAP1(1) AND m_RPE58(1) => SimExpr(YGL030W) : 6

RAP1(1) AND m_RPE6(1) => SimExpr(YGL030W) : 9

RAP1(1) AND m_RPE69(1) => SimExpr(YGL030W) : 6

m_RPE6(1) AND m_RPE8(1) => SimExpr(YGL030W) : 8

RAP1(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YGL030W) : 5

RAP1(1) AND m_RPE8(1) => SimExpr(YGL030W) : 9

RAP1(1) AND MCM1'(1) => SimExpr(YJR139C) OR SimExpr(other) : 18 2

RAP1(1) AND ALPHA2(1) => SimExpr(YJR139C) OR SimExpr(other) : 5 2

EXPR: (0.223) RAP1 (P < 0.054) ALPHA2 (P < 0.000)

RAP1(1) AND MCM1'(1) AND ALPHA1(1) => SimExpr(YJR139C) : 9

EXPR: (0.193) RAP1 (P < 0.003) ALPHA1 (P < 0.000) MCM1' (P < 0.000)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n12(1) AND CSRE(1) => SimExpr(YGR254W) OR SimExpr(other) : 5 2

EXPR: (0.186) m_allantoin_and_allantoate_transporters_orfnum2SD_n12 (P < 0.000) CSRE (P < 0.000) m_other_signal-transduction_activities_orfnum2SD_n8 (P < 0.001)

ORF SYMBOL P F C TF
YMR008C PLB1 glycerophospholipid metabolism ->
lipid metabolism lysophospholipase activity ->
phospholipase activity cell wall (sensu Fungi) ->
cell wall (sensu Fungi) RAP1
YLR362W STE11 protein amino acid phosphorylation, pseudohyphal growth, signal transduction during conjugation with cellular fusion ->
phosphorus metabolism, cell organization and biogenesis, signal transduction, conjugation, protein metabolism, perception of external stimulus, sexual reproduction, response to abiotic stimulus MAP kinase kinase kinase activity ->
protein serine/threonine kinase activity cytoplasm ->
cytoplasm HIR1
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
phosphopyruvate hydratase complex, cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
|YKR079C| NO SYMBOL BAS1
YOR215C NO SYMBOL
|YDL079C| MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
protein serine/threonine kinase activity MTH1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
Main: cell organization and biogenesis (0.40) protein serine/threonine kinase activity (0.40) cytoplasm (0.50) ACE2 (0.17)
Score: 0.30 0.10 0.17 0.000
P-value: 2.698E-02 (G-protein coupled receptor protein signaling pathway) 2.083E-01 (protein serine/threonine kinase activity) 4.869E+00 (cytoplasm) 9.256E-01 (MSN4)

RAP1(1) AND CSRE(1) => SimExpr(YGR254W) OR SimExpr(other) : 11 3

RAP1(1) AND MCM1'(1) => SimExpr(YGR254W) OR SimExpr(other) : 18 2

MCM1'(1) AND m_organization_of_cytoplasm_orfnum2SD_n72(1) => SimExpr(YGR254W) OR SimExpr(other) : 5 1

EXPR: (0.212) m_organization_of_cytoplasm_orfnum2SD_n72 (P < 0.139) MCM1' (P < 0.008)

ORF SYMBOL P F C TF
YNL134C NO SYMBOL CAD1, HAL9, HSF1, NDD1, YAP1
|YOR107W| RGS2 G-protein signaling\, coupled to cAMP nucleotide second messenger ->
signal transduction GTPase activator activity ->
GTPase activator activity PHD1, RAP1
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YPL203W TPK2 protein amino acid phosphorylation, pseudohyphal growth, RAS protein signal transduction ->
phosphorus metabolism, cell organization and biogenesis, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex
YDR074W TPS2 carbohydrate metabolism, response to stress ->
carbohydrate metabolism, response to stress trehalose phosphatase activity ->
trehalose phosphatase activity alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming) ->
alpha\, alpha-trehalose-phosphate synthase complex (UDP-forming)
YIL018W RPL2B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5
Main: biosynthesis (0.40) phosphopyruvate hydratase activity (0.20) cytoplasm (0.75) PDR1 RAP1 SWI5 YAP5 (0.50)
Score: 0.40 0.00 0.50 0.333
P-value: 1.048E-01 (intracellular signaling cascade) 2.077E+00 (enzyme activity) 6.295E-03 (unlocalized) 5.607E-02 (YAP5)

m_other_nutritional-response_activities_orfnum2SD_n11(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YGR254W) : 5

EXPR: (0.165) m_amino-acid_transport_orfnum2SD_n14 (P < 0.002) m_other_nutritional-response_activities_orfnum2SD_n11 (P < 0.003)

ORF SYMBOL P F C TF
YOR085W OST3 N-linked glycosylation, protein complex assembly, protein amino acid glycosylation ->
biosynthesis, protein metabolism, glycoprotein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity integral to membrane, oligosaccharyl transferase complex ->
integral to membrane, cytoplasm, endomembrane system
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YFL039C ACT1 cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter ->
transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex ->
cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex DIG1, ROX1, STE12
YNR001C CIT1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis citrate (SI)-synthase activity ->
citrate (SI)-synthase activity mitochondrial matrix, mitochondrion ->
cytoplasm RGM1
Main: biosynthesis (0.60) phosphopyruvate hydratase activity (0.20) cytoplasm (1.00) FKH2 (0.25)
Score: 0.50 0.00 1.00 0.000
P-value: 1.002E-01 (main pathways of carbohydrate metabolism) 4.329E-02 (lyase activity) 1.466E+00 (cytoplasm) 5.819E-01 (RGM1)

RAP1(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) => SimExpr(YKL006W) OR SimExpr(other) : 6 1

RAP1(1) AND MCM1'(1) => SimExpr(YKL006W) OR SimExpr(other) : 18 2

RAP1(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n4(1) => SimExpr(YKL006W) OR SimExpr(other) : 5 2

RAP1(1) AND m_RPE8(1) => SimExpr(YKL006W) : 9

RAP1(1) AND MCM1'(1) AND m_g-proteins_orfnum2SD_n12(1) => SimExpr(YKL006W) : 5

EXPR: (0.124) m_g-proteins_orfnum2SD_n12 (P < 0.000) RAP1 (P < 0.010) MCM1' (P < 0.000)

mRRPE(1) AND m_amino-acid_transport_orfnum2SD_n18(1) AND SCB(1) => SimExpr(YLR249W) OR SimExpr(other) : 6 2

SWI5(1) AND m_anion_transporters_orfnum2SD_n22(1) AND m_lipid_transporters_orfnum2SD_n8(1) => SimExpr(YLR249W) OR SimExpr(other) : 6 2

EXPR: (0.218) SWI5 (P < 0.000) m_anion_transporters_orfnum2SD_n22 (P < 0.003) m_lipid_transporters_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
|YOL051W| GAL11 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase II transcription mediator activity ->
RNA polymerase II transcription mediator activity mediator complex ->
nucleus
YMR139W RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MAL33, YJL206C
YMR044W IOC4 chromatin modeling ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein binding ->
protein binding nucleus ->
nucleus
|YOR240W| NO SYMBOL
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YDR134C NO SYMBOL ASH1, NRG1, SOK2, SWI4
YPL143W RPL33A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MET4, NDD1, PDR1, RAP1, RME1
YKL190W CNB1 cell ion homeostasis, cell wall organization and biogenesis, adaptation to pheromone during conjugation with cellular fusion ->
cell homeostasis, cell organization and biogenesis, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus calcium-dependent protein serine/threonine phosphatase activity ->
calcium-dependent protein serine/threonine phosphatase activity cytoplasm ->
cytoplasm ABF1
Main: protein metabolism (0.50) translation elongation factor activity (0.17) cytoplasm (0.60) ABF1 (0.20)
Score: 0.33 0.00 0.40 0.000
P-value: 2.843E+00 (protein biosynthesis) 3.060E+00 (binding) 1.044E+00 (ribosome) 6.584E-01 (MAL33)

m_g-proteins_orfnum2SD_n12(1) AND m_glyoxylate_cycle_orfnum2SD_n7(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YLR249W) OR SimExpr(other) : 5 2

EXPR: (0.173) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_cell_death_orfnum2SD_n8 (P < 0.001) m_glyoxylate_cycle_orfnum2SD_n7 (P < 0.000)

m_glyoxylate_cycle_orfnum2SD_n7(1) AND m_ion_transporters_orfnum2SD_n14(1) => SimExpr(YLR249W) OR SimExpr(other) : 5 1

RAP1(1) AND mRRPE(1) => SimExpr(YLR249W) OR SimExpr(other) : 7 3

RAP1(1) AND m_LFTE17(1) => SimExpr(YLR249W) : 7

RAP1(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YLR249W) : 8

RAP1(1) AND ALPHA1(1) AND SFF(1) AND m_g-proteins_orfnum2SD_n12(1) => SimExpr(YKR057W) : 5

EXPR: (0.093) SFF (P < 0.000) m_g-proteins_orfnum2SD_n12 (P < 0.000) RAP1 (P < 0.003) ALPHA1 (P < 0.000)

ABF1(1) AND m_biosynthesis_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n8(1) => SimExpr(YJR138W) OR SimExpr(other) : 5 1

EXPR: (0.170) ABF1 (P < 0.000) m_biosynthesis_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n8 (P < 0.001)

ORF SYMBOL P F C TF
YIL135C VHS2 G1/S transition of mitotic cell cycle ->
cell cycle ABF1, DAL82, INO2, MAC1, MTH1, ROX1
YGR089W NNF2 FZF1, MCM1, SRD1
|YHR131C| NO SYMBOL PHO4
YMR126C DLT1 GCR2, HAP3, PDR1, RIM101, RTG1
YIR010W DSN1 chromosome segregation ->
cell cycle ABF1
YJR138W IML1 ABF1, DOT6, GCR2, MET31, REB1
Main: cell cycle (1.00) ABF1 (0.50)
Score: 1.00 0.267
P-value: 1.132E+00 (cell cycle) 1.002E-01 (ABF1)

CSRE(1) AND m_RPE34(1) => SimExpr(YNL069C) OR SimExpr(other) : 9 1

m_RPE8(1) AND CSRE(1) => SimExpr(YNL069C) OR SimExpr(other) : 11 4

MCM1'(1) AND HAP234(1) => SimExpr(YNL069C) OR SimExpr(other) : 9 4

RAP1(1) AND m_metabolism_of_energy_reserves_orfnum2SD_n8(1) => SimExpr(YNL069C) : 5

m_RPE72(1) AND m_RPE8(1) => SimExpr(YNL069C) : 5

RAP1(1) AND m_RPE72(1) => SimExpr(YNL069C) : 5

RAP1(1) AND m_RPE8(1) => SimExpr(YNL069C) : 9

CSRE(1) AND HAP234(1) => SimExpr(YNL069C) : 6

RAP1(1) AND m_RPE58(1) => SimExpr(YNL069C) : 6

m_other_transport_facilitators_orfnum2SD_n10(1) AND MCM1(1) => SimExpr(YOR051C) OR SimExpr(other) : 8 1

m_other_transport_facilitators_orfnum2SD_n10(1) AND mRRPE(1) => SimExpr(YOR051C) : 5

m_other_transport_facilitators_orfnum2SD_n10(1) AND MCM1(1) AND SFF'(1) => SimExpr(YOR051C) : 7

EXPR: (0.174) SFF' (P < 0.000) m_other_transport_facilitators_orfnum2SD_n10 (P < 0.000) MCM1 (P < 0.000)

ORF SYMBOL P F C TF
YOR273C TPO4 polyamine transport ->
transport spermine transporter activity, spermidine transporter activity ->
spermine transporter activity, spermidine transporter activity plasma membrane, vacuolar membrane ->
plasma membrane, cytoplasm ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YGR086C PIL1 ASH1, SWI5
YJL158C CIS3 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transketolase activity cytoplasm ->
cytoplasm REB1
YKL104C GFA1 cell wall chitin biosynthesis ->
cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity ->
glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity REB1
YOR051C NO SYMBOL PHD1, SFL1
Main: cell organization and biogenesis (0.60) structural constituent of cell wall (0.20) cytoplasm (1.00) REB1 (0.43)
Score: 0.40 0.00 1.00 0.286
P-value: 2.979E-01 (external encapsulating structure organization and biogenesis) 1.225E+00 (transferase activity) 4.928E-01 (plasma membrane) 3.726E-02 (REB1)

m_g-proteins_orfnum2SD_n12(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) AND m_anion_transporters_orfnum2SD_n23(1) => SimExpr(YNL045W) OR SimExpr(other) : 5 2

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_peroxisomal_transport_orfnum2SD_n22(1) => SimExpr(YNL045W) : 6

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND SFF'(1) AND CSRE(1) AND ALPHA1'(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YGR101W) OR SimExpr(other) : 6 2

EXPR: (0.206) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) SFF' (P < 0.000) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) CSRE (P < 0.000) ALPHA1' (P < 0.001)

ALPHA1(1) AND m_other_morphogenetic_activities_orfnum2SD_n7(1) AND SFF'(1) AND CSRE(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YGR101W) OR SimExpr(other) : 5 2

EXPR: (0.203) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) SFF' (P < 0.000) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) CSRE (P < 0.000) ALPHA1 (P < 0.000)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n12(1) AND CSRE(1) => SimExpr(YOR215C) OR SimExpr(other) : 6 1

m_metabolism_of_energy_reserves_orfnum2SD_n27(1) AND CSRE(1) => SimExpr(YPL273W) OR SimExpr(other) : 6 2

EXPR: (0.214) m_metabolism_of_energy_reserves_orfnum2SD_n27 (P < 0.003) CSRE (P < 0.002)

ORF SYMBOL P F C TF
YOL019W NO SYMBOL SWI4
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YPL273W SAM4 sulfur amino acid metabolism ->
amine metabolism, sulfur metabolism, amino acid and derivative metabolism, organic acid metabolism homocysteine S-methyltransferase activity ->
homocysteine S-methyltransferase activity DAL81
YLR205C HMX1 iron ion homeostasis ->
cell homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
|YGL209W| MIG2 glucose metabolism, regulation of transcription from Pol II promoter ->
alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus CIN5
|YOR152C| NO SYMBOL HIR2
YKL152C GPM1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphoglycerate mutase activity ->
phosphoglycerate mutase activity cytosol ->
cytoplasm GCR1, GCR2, HSF1, RAP1
YNL231C PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
Main: alcohol metabolism (0.50) phosphatidylinositol transporter activity (0.17) cytoplasm (0.60) SWI4 HSF1 (0.25)
Score: 0.40 0.00 0.30 0.071
P-value: 5.981E-02 (alcohol metabolism) 6.082E-01 (oxidoreductase activity) 4.664E+00 (cytoplasm) 2.553E-01 (HSF1)

m_amino-acid_degradation_orfnum2SD_n24(1) AND m_other_nutritional-response_activities_orfnum2SD_n10(1) => SimExpr(YGR147C) OR SimExpr(other) : 5 1

EXPR: (0.187) m_amino-acid_degradation_orfnum2SD_n24 (P < 0.001) m_other_nutritional-response_activities_orfnum2SD_n10 (P < 0.001)

ORF SYMBOL P F C TF
YDL040C NAT1 protein amino acid acetylation ->
protein metabolism peptide alpha-N-acetyltransferase activity ->
peptide alpha-N-acetyltransferase activity intracellular, cytoplasm ->
intracellular
|YHR131C| NO SYMBOL PHO4
YJL172W CPS1 nitrogen metabolism, proteolysis and peptidolysis ->
nitrogen metabolism, catabolism, protein metabolism gly-X carboxypeptidase activity ->
gly-X carboxypeptidase activity vacuole (sensu Fungi) ->
intracellular PHO4
YIL167W NO SYMBOL
YGR147C NAT2 N-terminal peptidyl-methionine acetylation ->
protein metabolism, protein modification peptide alpha-N-acetyltransferase activity ->
peptide alpha-N-acetyltransferase activity cytoplasm ->
intracellular HIR1, REB1
YMR016C SOK2 pseudohyphal growth ->
cell organization and biogenesis transcription factor activity ->
transcription factor activity PHD1, SKN7, SWI4, SWI6
Main: protein metabolism (0.75) peptide alpha-N-acetyltransferase activity (0.50) intracellular (1.00) PHO4 (0.50)
Score: 0.50 0.17 1.00 0.167
P-value: 3.862E-03 (protein amino acid acetylation) 5.770E-04 (peptide alpha-N-acetyltransferase activity) 3.918E+00 (cytoplasm) 6.216E-02 (PHO4)

RPN4(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YOL038W) OR SimExpr(other) : 11 5

EXPR: (0.231) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.003) RPN4 (P < 0.034)

m_phosphate_transport_orfnum2SD_n5(1) AND RPN4(1) => SimExpr(YOL038W) OR SimExpr(other) : 5 1

EXPR: (0.194) m_phosphate_transport_orfnum2SD_n5 (P < 0.005) RPN4 (P < 0.014)

ORF SYMBOL P F C TF
YGR124W ASN2 asparagine biosynthesis ->
asparagine biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity ASH1, ROX1
YKL160W ELF1 cell growth ->
cell growth
YOR052C NO SYMBOL
YDL007W RPT2 ubiquitin-dependent protein catabolism ->
ubiquitin-dependent protein catabolism ATPase activity, endopeptidase activity ->
ATPase activity, endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
proteasome complex (sensu Eukarya) REB1
|YGL096W| TOS8 transcription factor activity ->
transcription factor activity IXR1, SOK2, SWI4
YOL038W PRE6 ubiquitin-dependent protein catabolism ->
ubiquitin-dependent protein catabolism endopeptidase activity ->
endopeptidase activity proteasome core complex (sensu Eukarya) ->
proteasome complex (sensu Eukarya)
Main: ubiquitin-dependent protein catabolism (0.50) endopeptidase activity (0.50) proteasome complex (sensu Eukarya) (1.00) SWI4 (0.33)
Score: 0.17 0.17 1.00 0.000
P-value: 1.312E-01 (ubiquitin-dependent protein catabolism) 2.026E-02 (endopeptidase activity) 2.220E-02 (proteasome complex (sensu Eukarya)) 3.475E-01 (ASH1)

m_nitrogen_and_sulphur_metabolism_orfnum2SD_n29(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YOL038W) OR SimExpr(other) : 6 1

EXPR: (0.190) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.003) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n29 (P < 0.003)

ORF SYMBOL P F C TF
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
intracellular ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
|YAR044W| OSH1 steroid biosynthesis ->
biosynthesis, lipid metabolism oxysterol binding, phosphatidylinositol binding ->
oxysterol binding, phosphatidylinositol binding Golgi trans cisterna, early endosome, endoplasmic reticulum ->
intracellular
YOR316C COT1 cobalt ion transport, zinc ion transport, zinc ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity ->
di-\, tri-valent inorganic cation transporter activity, zinc ion transporter activity, transition metal ion transporter activity vacuole (sensu Fungi) ->
intracellular FKH2, INO2, INO4, NDD1, RAP1
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrion ->
intracellular GCN4, MET4
YKR039W GAP1 amino acid transport ->
transport general amino acid permease activity ->
amino acid transporter activity, polyamine transporter activity, porter activity integral to plasma membrane ->
integral to membrane, plasma membrane CIN5, YAP6
YGR019W UGA1 nitrogen utilization ->
nitrogen metabolism 4-aminobutyrate aminotransferase activity ->
transaminase activity intracellular ->
intracellular IXR1
YOL038W PRE6 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome core complex (sensu Eukarya) ->
intracellular
Main: biosynthesis (0.29) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.29) intracellular (0.86) FKH2 NDD1 (0.40)
Score: 0.14 0.05 0.71 0.100
P-value: 1.034E+00 (catabolism) 7.413E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 5.219E-01 (endoplasmic reticulum) 3.215E-01 (NDD1)

m_pheromone_response_generation_orfnum2SD_n12(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YOL038W) : 5

EXPR: (0.177) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.003) m_pheromone_response_generation_orfnum2SD_n12 (P < 0.013)

m_metabolism_of_energy_reserves_orfnum2SD_n27(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YFL039C) OR SimExpr(other) : 5 2

EXPR: (0.233) m_metabolism_of_energy_reserves_orfnum2SD_n27 (P < 0.012) m_amino-acid_transport_orfnum2SD_n14 (P < 0.010)

ORF SYMBOL P F C TF
YOL019W NO SYMBOL SWI4
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
main pathways of carbohydrate metabolism, carboxylic acid metabolism L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
|YOR173W| DCS2 CAD1
YFL039C ACT1 cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter ->
cytokinesis, exocytosis, endocytosis, response to osmotic stress, cell wall organization and biogenesis, bud growth, protein secretion, sporulation (sensu Saccharomyces), chromosome organization and biogenesis (sensu Eukarya), regulation of transcription, cell cycle, protein amino acid acetylation, organelle organization and biogenesis, transcription from Pol II promoter, M phase, DNA packaging, transcription\, DNA-dependent, mitotic cell cycle structural constituent of cytoskeleton ->
structural constituent of cytoskeleton actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex ->
cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex DIG1, ROX1, STE12
YLR205C HMX1 iron ion homeostasis ->
cation homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
|YHR056C| RSC30 regulation of transcription\, DNA-dependent ->
regulation of transcription, transcription\, DNA-dependent DNA binding ->
DNA binding RSC complex ->
nucleus GAT1
YGR180C RNR4 DNA replication ->
DNA replication and chromosome cycle, mitotic cell cycle, DNA metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity nucleus, cytoplasm ->
nucleus, cytoplasm CIN5, MBP1, RAP1, RFX1, SWI6
Main: mitotic cell cycle (0.40) DNA binding (0.20) cytoplasm (0.60) SWI4 (0.14)
Score: 0.20 0.00 0.50 0.000
P-value: 9.707E-01 (regulation of transcription\, DNA-dependent) 6.210E-02 (oxidoreductase activity) 5.445E-01 (nucleoplasm) 9.017E-01 (GAT1)

m_lipid_and_fatty-acid_transport_orfnum2SD_n11(1) AND m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n12(1) AND ALPHA1'(1) => SimExpr(YML028W) OR SimExpr(other) : 6 2

EXPR: (0.203) m_lipid_and_fatty-acid_transport_orfnum2SD_n11 (P < 0.002) m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n12 (P < 0.014) ALPHA1' (P < 0.001)

ORF SYMBOL P F C TF
YOL048C NO SYMBOL SKN7
|YOL051W| GAL11 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase II transcription mediator activity ->
RNA polymerase II transcription mediator activity mediator complex ->
nucleus
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YML028W TSA1 response to oxidative stress, regulation of redox homeostasis ->
oxygen and reactive oxygen species metabolism, cell homeostasis, response to biotic stimulus thioredoxin peroxidase activity ->
thioredoxin peroxidase activity cytoplasm ->
cytoplasm MBP1, NDD1, SKN7, YAP1
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YPL154C PEP4 microautophagy, vacuolar protein catabolism, sporulation, cellular response to starvation ->
autophagy, catabolism, sporulation, response to extracellular stimulus, protein metabolism, response to biotic stimulus saccharopepsin activity, endopeptidase activity ->
saccharopepsin activity, endopeptidase activity vacuole (sensu Fungi) ->
cytoplasm
|YNR059W| MNT4 O-linked glycosylation ->
biosynthesis, protein metabolism alpha-1\,3-mannosyltransferase activity ->
alpha-1\,3-mannosyltransferase activity
Main: protein metabolism (0.57) protein transporter activity (0.14) cytoplasm (0.80) SKN7 (0.40)
Score: 0.43 0.00 0.60 0.100
P-value: 2.461E-01 (response to biotic stimulus) 2.037E+00 (enzyme activity) 3.922E+00 (cytoplasm) 4.344E-01 (SKN7)

m_glyoxylate_cycle_orfnum2SD_n8(1) AND HAP234(1) => SimExpr(YML028W) OR SimExpr(other) : 5 2

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) => SimExpr(YKL185W) OR SimExpr(other) : 6 2

m_pheromone_response_generation_orfnum2SD_n10(1) AND m_other_energy_generation_activities_orfnum2SD_n22(1) => SimExpr(YKL185W) OR SimExpr(other) : 6 2

EXPR: (0.216) m_pheromone_response_generation_orfnum2SD_n10 (P < 0.002) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.004)

ORF SYMBOL P F C TF
|YPR022C| NO SYMBOL
YLR362W STE11 protein amino acid phosphorylation, pseudohyphal growth, signal transduction during conjugation with cellular fusion ->
phosphorus metabolism, cell organization and biogenesis, signal transduction, conjugation, protein metabolism, perception of external stimulus, sexual reproduction, response to abiotic stimulus MAP kinase kinase kinase activity ->
MAP kinase kinase kinase activity cytoplasm ->
cytoplasm HIR1
YLR425W TUS1 signal transduction, cell wall organization and biogenesis ->
signal transduction, cell organization and biogenesis Rho guanyl-nucleotide exchange factor activity ->
Rho guanyl-nucleotide exchange factor activity UGA3
YPR019W CDC54 DNA unwinding, DNA replication initiation, pre-replicative complex formation and maintenance ->
cell proliferation, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism chromatin binding, ATP dependent DNA helicase activity ->
chromatin binding, ATP dependent DNA helicase activity cytoplasm, nucleus, pre-replicative complex ->
cytoplasm, nucleus
YGR237C NO SYMBOL
|YJR007W| SUI2 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex GLN3, HAP3, HIR1, RCS1
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
YNL003C PET8 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane MATa1
Main: cell organization and biogenesis (0.50) specific transcriptional repressor activity (0.17) cytoplasm (0.80) HIR1 (0.40)
Score: 0.33 0.00 0.70 0.100
P-value: 1.298E-01 (pseudohyphal growth) 1.413E-01 (receptor signaling protein activity) 4.706E+00 (cytoplasm) 7.608E-02 (HIR1)

m_drug_transporters_orfnum2SD_n7(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) => SimExpr(YKL185W) OR SimExpr(other) : 5 2

EXPR: (0.207) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.001) m_drug_transporters_orfnum2SD_n7 (P < 0.001)

ORF SYMBOL P F C TF
|YFL036W| RPO41 mitochondrial genome maintenance, transcription from mitochondrial promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity mitochondrial matrix ->
cytoplasm
|YOR034C| AKR2 SFL1
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane
YJL048C NO SYMBOL INO4, MAC1, MET4, SKN7
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
YNL231C PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
Main: cell organization and biogenesis (0.60) structural constituent of cell wall (0.20) cytoplasm (0.40) SWI4 SMP1 (0.40)
Score: 0.40 0.00 0.10 0.200
P-value: 1.408E-02 (response to drug) 9.633E-01 (transporter activity) 4.869E+00 (cytoplasm) 8.587E-02 (SMP1)

m_drug_transporters_orfnum2SD_n7(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) => SimExpr(YKL185W) OR SimExpr(other) : 5 2

EXPR: (0.230) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.009) m_drug_transporters_orfnum2SD_n7 (P < 0.012)

ORF SYMBOL P F C TF
|YFR028C| CDC14 DNA dependent DNA replication, protein amino acid dephosphorylation, regulation of exit from mitosis ->
phosphorus metabolism, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein phosphatase activity ->
protein phosphatase activity nucleus, spindle pole body, nucleolus ->
cytoplasm, nucleus, microtubule organizing center
YOL087C NO SYMBOL DAL82
|YOR034C| AKR2 SFL1
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YOR273C TPO4 polyamine transport ->
transport spermine transporter activity, spermidine transporter activity ->
spermine transporter activity, spermidine transporter activity plasma membrane, vacuolar membrane ->
plasma membrane, cytoplasm ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
YNL231C PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
Main: transport (0.40) specific transcriptional repressor activity (0.20) cytoplasm (0.80) IME4 (0.33)
Score: 0.20 0.00 0.70 0.067
P-value: 3.490E+00 (transport) 7.707E-01 (transporter activity) 3.953E+00 (cytoplasm) 4.191E-02 (IME4)

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) => SimExpr(YKL185W) OR SimExpr(other) : 5 2

EXPR: (0.241) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.024) m_other_morphogenetic_activities_orfnum2SD_n8 (P < 0.021)

ORF SYMBOL P F C TF
YNL059C ARP5 protein-vacuolar targeting ->
cell organization and biogenesis, protein metabolism, transport nucleus ->
nucleus ABF1, GRF10(Pho2)
|YHR003C| NO SYMBOL HAP4, SWI6, THI2
YIL069C RPS24B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, INO2, MCM1, RAP1
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
|YOL159C| NO SYMBOL ARO80, CIN5, RLM1
YLR297W NO SYMBOL
YDL128W VCX1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cytoplasm, vacuole MAC1, STE12
Main: cell organization and biogenesis (0.50) specific transcriptional repressor activity (0.33) cytoplasm (0.50) ABF1 (0.17)
Score: 0.50 0.00 0.33 0.000
P-value: 3.926E+00 (transport) 2.000E+00 4.624E+00 (nucleus) 7.090E-01 (THI2)

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_phosphate_transport_orfnum2SD_n8(1) AND ALPHA1'(1) => SimExpr(YKL185W) : 5

EXPR: (0.155) m_phosphate_transport_orfnum2SD_n8 (P < 0.000) ALPHA1' (P < 0.000) m_other_morphogenetic_activities_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YMR142C RPL13B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic large ribosomal subunit (sensu Eukarya) FHL1, GAT3, RAP1, RGM1, YAP5
YFR045W NO SYMBOL FKH1, PHO4, RIM101, UGA3, USV1
YGR281W YOR1 transport, response to drug ->
transport, response to drug xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane
YIL052C RPL34B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic large ribosomal subunit (sensu Eukarya) RME1
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
regulation of transcription\, mating-type specific, pseudohyphal growth specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
Main: protein biosynthesis (0.50) structural constituent of ribosome (0.50) cytosolic large ribosomal subunit (sensu Eukarya) (0.50) USV1 (0.25)
Score: 0.17 0.17 0.17 0.000
P-value: 1.065E+00 (protein biosynthesis) 1.370E-01 (structural constituent of ribosome) 5.788E-02 (cytosolic large ribosomal subunit (sensu Eukarya)) 4.412E-01 (RIM101)

MCM1'(1) AND SFF(1) AND m_fermentation_orfnum2SD_n5(1) => SimExpr(YDR305C) OR SimExpr(other) : 7 3

EXPR: (0.220) SFF (P < 0.000) m_fermentation_orfnum2SD_n5 (P < 0.002) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YKR004C ECM9 cell wall organization and biogenesis ->
cell organization and biogenesis RTG3
YOR274W MOD5 tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism tRNA isopentenyltransferase activity ->
transferase activity\, transferring alkyl or aryl (other than methyl) groups nucleus, nucleolus, mitochondrion, cytosol ->
nucleus, mitochondrion, cytoplasm ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
|YDR380W| ARO10 leucine catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism carboxy-lyase activity, pyruvate decarboxylase activity ->
carbon-carbon lyase activity ARO80, MTH1
YDR305C HNT2 nucleoside catabolism ->
catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hydrolase activity, nucleoside triphosphatase activity ->
hydrolase activity
YMR106C YKU80 double-strand break repair via nonhomologous end-joining, telomere maintenance, double-strand break repair via homologous recombination, chromatin assembly/disassembly, transcriptional gene silencing ->
cell organization and biogenesis, regulation of transcription, response to biotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription\, DNA-dependent damaged DNA binding ->
DNA binding nuclear chromatin, nuclear telomeric heterochromatin ->
chromosome\, telomeric region, chromosome, nucleus MOT3
|YMR102C| NO SYMBOL
YGR023W MTL1 cell wall organization and biogenesis ->
cell organization and biogenesis integral to plasma membrane ->
integral to membrane, plasma membrane
YNL250W RAD50 double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication, telomerase-independent telomere maintenance ->
cell organization and biogenesis, cell proliferation, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, response to biotic stimulus ATPase activity, protein binding, double-stranded DNA binding ->
purine nucleotide binding, protein binding, DNA binding, hydrolase activity nucleus ->
nucleus ABF1, MAC1
YGR193C PDX1 acetyl-CoA biosynthesis from pyruvate ->
biosynthesis, coenzymes and prosthetic group metabolism, organic acid metabolism protein binding ->
protein binding mitochondrion, pyruvate dehydrogenase complex (sensu Eukarya) ->
cytoplasm, pyruvate dehydrogenase complex SWI4
|YMR088C| NO SYMBOL
Main: cell organization and biogenesis (0.50) DNA binding (0.33) nucleus (0.60) ARO80 (0.33)
Score: 0.50 0.20 0.40 0.067
P-value: 2.232E-02 (double-strand break repair via nonhomologous end-joining) 1.258E+00 (protein binding) 2.713E+00 (mitochondrion) 1.309E-01 (ARO80)

m_glycolysis_and_gluconeogenesis_orfnum2SD_n4(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) => SimExpr(YGL189C) OR SimExpr(other) : 5 1

m_allantoin_and_allantoate_transporters_orfnum2SD_n6(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) => SimExpr(YGL189C) OR SimExpr(other) : 5 2

m_allantoin_and_allantoate_transporters_orfnum2SD_n11(1) AND mRRPE(1) => SimExpr(YNR046W) OR SimExpr(other) : 7 3

EXPR: (0.218) mRRPE (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n11 (P < 0.000)

m_nitrogen_and_sulphur_transport_orfnum2SD_n5(1) AND mRRPE(1) => SimExpr(YNR046W) OR SimExpr(other) : 5 2

EXPR: (0.204) m_nitrogen_and_sulphur_transport_orfnum2SD_n5 (P < 0.000) mRRPE (P < 0.000)

ORF SYMBOL P F C TF
|YGR144W| THI4 DNA repair, thiamin biosynthesis ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, vitamin metabolism mitochondrion ->
cytoplasm ABF1, CIN5
|YKL014C| NO SYMBOL ABF1
YNR046W NO SYMBOL ABF1
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YNR054C NO SYMBOL HAP3, HAP5, IXR1, MCM1, RTG3, SFP1, SWI6
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
YMR131C RRB1 ribosome biogenesis ->
cell organization and biogenesis nucleolus ->
nucleus FZF1, MATa1, RGT1
Main: cell organization and biogenesis (0.50) translation elongation factor activity (0.50) cytoplasm (0.67) ABF1 (0.43)
Score: 0.33 0.00 0.33 0.190
P-value: 3.379E+00 (cytoplasm organization and biogenesis) 2.000E+00 4.869E+00 (cytoplasm) 1.665E-01 (ABF1)

m_deoxyribonucleotide_metabolism_orfnum2SD_n27(1) AND m_nutritional_response_pathway_orfnum2SD_n8(1) => SimExpr(YDL128W) OR SimExpr(other) : 5 2

EXPR: (0.222) m_deoxyribonucleotide_metabolism_orfnum2SD_n27 (P < 0.010) m_nutritional_response_pathway_orfnum2SD_n8 (P < 0.005)

ORF SYMBOL P F C TF
|YNL186W| UBP10 protein deubiquitination ->
catabolism, protein metabolism ubiquitin-specific protease activity ->
ubiquitin-specific protease activity nucleus ->
nucleus ABF1
YKL183W LOT5
YDR380W ARO10 leucine catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism carboxy-lyase activity, pyruvate decarboxylase activity ->
carboxy-lyase activity, pyruvate decarboxylase activity ARO80, MTH1
|YGR014W| MSB2 establishment of cell polarity (sensu Saccharomyces), response to osmotic stress ->
response to abiotic stimulus, cell organization and biogenesis osmosensor activity ->
osmosensor activity integral to plasma membrane ->
integral to membrane, plasma membrane DIG1, STE12, SWI4, SWI6
YNL208W NO SYMBOL INO2
YGR180C RNR4 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity nucleus, cytoplasm ->
nucleus, cytoplasm CIN5, MBP1, RAP1, RFX1, SWI6
YDL128W VCX1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cytoplasm, vacuole MAC1, STE12
Main: catabolism (0.40) ubiquitin-specific protease activity (0.20) cytoplasm (0.50) STE12 SWI6 (0.33)
Score: 0.10 0.00 0.33 0.133
P-value: 8.039E-01 (catabolism) 2.414E+00 (enzyme activity) 3.518E+00 (membrane) 1.487E-01 (STE12)

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) => SimExpr(YDL128W) OR SimExpr(other) : 5 2

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) => SimExpr(YDL128W) OR SimExpr(other) : 7 1

m_deoxyribonucleotide_metabolism_orfnum2SD_n12(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n4(1) => SimExpr(YDL128W) OR SimExpr(other) : 8 3

EXPR: (0.228) m_deoxyribonucleotide_metabolism_orfnum2SD_n4 (P < 0.008) m_deoxyribonucleotide_metabolism_orfnum2SD_n12 (P < 0.000)

m_amino-acid_degradation_orfnum2SD_n8(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n4(1) => SimExpr(YDL128W) OR SimExpr(other) : 5 2

EXPR: (0.197) m_deoxyribonucleotide_metabolism_orfnum2SD_n4 (P < 0.004) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YNR050C LYS9 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis saccharopine dehydrogenase (NADP+\, L-glutamate forming) activity ->
saccharopine dehydrogenase (NADP+\, L-glutamate forming) activity cytoplasm ->
cytoplasm AZF1, GCR2, HAL9, HAP5, HIR2, LEU3, MET31, RLM1, ROX1, SMP1, SRD1, STP1, USV1, YAP6
|YPR125W| NO SYMBOL MAC1
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YJR123W RPS5 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GRF10(Pho2), HSF1, MSN4, YAP1
|YAR050W| FLO1 flocculation ->
cell adhesion cell adhesion molecule activity ->
cell adhesion molecule activity cell wall (sensu Fungi) ->
cell wall DIG1, FKH1, GCN4, MBP1, MCM1, MSN4, RME1, SKN7, STE12
YOR095C RKI1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism ribose-5-phosphate isomerase activity ->
ribose-5-phosphate isomerase activity FHL1, FKH2, RAP1
YDL128W VCX1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cytoplasm, vacuole MAC1, STE12
Main: biosynthesis (0.33) protein transporter activity (0.17) cytoplasm (0.80) MAC1 STE12 FHL1 MSN4 (0.29)
Score: 0.20 0.00 0.60 0.190
P-value: 3.926E+00 (transport) 7.707E-01 (transporter activity) 3.016E+00 (membrane) 9.698E-02 (MSN4)

m_deoxyribonucleotide_metabolism_orfnum2SD_n27(1) AND m_anion_transporters_orfnum2SD_n4(1) => SimExpr(YDL128W) OR SimExpr(other) : 7 3

EXPR: (0.252) m_deoxyribonucleotide_metabolism_orfnum2SD_n27 (P < 0.014) m_anion_transporters_orfnum2SD_n4 (P < 0.046)

ORF SYMBOL P F C TF
|YJL006C| CTK2 regulation of transcription from Pol II promoter, protein amino acid phosphorylation ->
phosphorus metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity nucleus ->
nucleus MTH1
YKR042W UTH1 mitochondrion organization and biogenesis ->
cell organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
YOL012C HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
|YGL046W| NO SYMBOL
YKR091W SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm DIG1, RLM1, STE12
YOL120C RPL18A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MAL13, RAP1, YAP5
|YGR050C| NO SYMBOL DAL82, FKH2, HSF1, INO4, MAL13, NRG1, RAP1, SKN7, SWI4
YDL128W VCX1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cytoplasm, vacuole MAC1, STE12
YJR040W GEF1 cation homeostasis ->
cell homeostasis voltage-gated chloride channel activity ->
voltage-gated chloride channel activity Golgi vesicle ->
cytoplasm DOT6, MTH1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.38) cyclin-dependent protein kinase\, regulator activity (0.17) cytoplasm (0.75) SWI4 STE12 (0.33)
Score: 0.25 0.00 0.57 0.222
P-value: 2.578E-01 (cation homeostasis) 1.319E+00 (transporter activity) 2.811E+00 (cytosol) 3.554E-02 (STE12)

m_amino-acid_transport_orfnum2SD_n3(1) AND m_cytok9(1) => SimExpr(YOR347C) OR SimExpr(other) : 6 2

EXPR: (0.198) m_cytok9 (P < 0.000) m_amino-acid_transport_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
YOR347C PYK2 pyruvate metabolism, glycolysis ->
organic acid metabolism, alcohol metabolism, pyruvate dehydrogenase bypass, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism pyruvate kinase activity ->
pyruvate kinase activity cytosol ->
cytoplasm ZMS1
YMR002W NO SYMBOL NDD1, REB1, SWI6
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YGR184C UBR1 protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity proteasome complex (sensu Eukarya) ->
cytoplasm, nucleus HMS1, REB1, RIM101
|YGR086C| PIL1 ASH1, SWI5
YGR008C STF2 response to dessication, ATP synthesis coupled proton transport ->
response to abiotic stimulus, transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane INO2
YLR270W DCS1 deadenylation-dependent decapping ->
catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides ->
hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides MATa1
|YIR015W| RPR2 tRNA processing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonuclease P activity ->
ribonuclease P activity nucleolar ribonuclease P complex ->
nucleus, ribonucleoprotein complex
Main: catabolism (0.50) pyruvate kinase activity (0.20) cytoplasm (0.80) REB1 (0.29)
Score: 0.33 0.00 0.70 0.048
P-value: 1.976E-01 (main pathways of carbohydrate metabolism) 1.625E+00 (enzyme activity) 1.795E+00 (cytosol) 3.834E-01 (REB1)

m_lipid_and_fatty-acid_binding_orfnum2SD_n12(1) AND m_phosphate_transport_orfnum2SD_n5(1) => SimExpr(YJL145W) : 5

EXPR: (0.182) m_phosphate_transport_orfnum2SD_n5 (P < 0.001) m_lipid_and_fatty-acid_binding_orfnum2SD_n12 (P < 0.002)

ORF SYMBOL P F C TF
YHR039C MSC7 meiotic recombination ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
YLR420W URA4 pyrimidine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism dihydroorotase activity ->
dihydroorotase activity SFP1
YJL145W SFH5 phospholipid transport ->
transport phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity DIG1, HAP3, NRG1, RCS1, RFX1
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YNL231C PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
Main: biosynthesis (0.60) phosphatidylinositol transporter activity (0.50) cytoplasm (1.00) HAP3 (0.25)
Score: 0.50 0.17 1.00 0.000
P-value: 5.455E-04 (phospholipid transport) 7.686E-04 (phosphatidylinositol transporter activity) 4.460E+00 (cytoplasm) 8.521E-01 (SFP1)

m_lipid_and_fatty-acid_binding_orfnum2SD_n13(1) AND m_glyoxylate_cycle_orfnum2SD_n11(1) => SimExpr(YJL145W) : 8

EXPR: (0.199) m_glyoxylate_cycle_orfnum2SD_n11 (P < 0.000) m_lipid_and_fatty-acid_binding_orfnum2SD_n13 (P < 0.000)

ORF SYMBOL P F C TF
YOL012C HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
YOR354C MSC6 meiotic recombination ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ABF1, FHL1, GAT1
YJL145W SFH5 phospholipid transport ->
transport phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity DIG1, HAP3, NRG1, RCS1, RFX1
YOR312C RPL20B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, FKH2, GAT3, RAP1
YJR015W NO SYMBOL
YHR208W BAT1 branched chain family amino acid biosynthesis, amino acid catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis, catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity mitochondrial matrix ->
cytoplasm LEU3, PHO4
YAL061W NO SYMBOL
YNL231C PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
Main: biosynthesis (0.50) phosphatidylinositol transporter activity (0.40) cytoplasm (0.75) SWI4 FHL1 (0.33)
Score: 0.33 0.10 0.50 0.133
P-value: 1.662E-03 (phospholipid transport) 1.950E-03 (phosphatidylinositol transporter activity) 4.664E+00 (cytoplasm) 3.880E-01 (FHL1)

SFF'(1) AND m_amino-acid_transport_orfnum2SD_n20(1) AND m_anion_transporters_orfnum2SD_n10(1) => SimExpr(YLR425W) OR SimExpr(other) : 5 2

EXPR: (0.219) SFF' (P < 0.000) m_anion_transporters_orfnum2SD_n10 (P < 0.000) m_amino-acid_transport_orfnum2SD_n20 (P < 0.004)

ORF SYMBOL P F C TF
YNL162W RPL42A protein biosynthesis ->
macromolecule biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1, YAP5
YLR425W TUS1 signal transduction, cell wall organization and biogenesis ->
signal transduction, external encapsulating structure organization and biogenesis Rho guanyl-nucleotide exchange factor activity ->
guanyl nucleotide binding, small GTPase regulatory/interacting protein activity UGA3
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds L-malate dehydrogenase activity ->
malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YOL086C ADH1 fermentation ->
energy derivation by oxidation of organic compounds alcohol dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytosol ->
cytoplasm GCR1, GCR2, GTS1, RAP1
YMR298W NO SYMBOL CIN5
|YNL287W| SEC21 ER to Golgi transport, retrograde (Golgi to ER) transport ->
intracellular transport, secretory pathway, vesicle-mediated transport COPI vesicle coat ->
cytoplasm ABF1
|YFL030W| AGX1 glyoxylate cycle ->
aldehyde metabolism, carbohydrate metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds alanine-glyoxylate aminotransferase activity ->
transaminase activity
Main: energy derivation by oxidation of organic compounds (0.50) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.40) cytoplasm (1.00) RAP1 (0.33)
Score: 0.20 0.10 1.00 0.067
P-value: 4.098E-02 (energy pathways) 6.354E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 1.086E+00 (cytosol) 8.141E-01 (RAP1)

ALPHA2'(1) AND m_anion_transporters_orfnum2SD_n17(1) => SimExpr(YKL178C) OR SimExpr(other) : 5 2

EXPR: (0.210) m_anion_transporters_orfnum2SD_n17 (P < 0.004) ALPHA2' (P < 0.006)

ORF SYMBOL P F C TF
YMR142C RPL13B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, YAP5
|YMR122C| NO SYMBOL SWI5
YPR035W GLN1 nitrogen metabolism, glutamine biosynthesis ->
nitrogen metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis glutamate-ammonia ligase activity ->
glutamate-ammonia ligase activity cytoplasm ->
cytoplasm CIN5, DAL81, FKH1, FKH2, GLN3, HSF1, INO4, MSN1, REB1, SWI4
|YLR355C| ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
ketol-acid reductoisomerase activity mitochondrion ->
cytoplasm GCN4, MET4
YKL178C STE3 signal transduction during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus mating-type a-factor pheromone receptor activity ->
mating-type a-factor pheromone receptor activity integral to plasma membrane ->
integral to membrane, plasma membrane SFP1, SUM1, YFL044C
YKL193C SDS22 protein targeting, chromosome segregation ->
cell proliferation, protein metabolism, transport enzyme regulator activity, protein phosphatase type 1\, regulator activity ->
enzyme regulator activity, protein phosphatase type 1\, regulator activity cytoplasm, nucleus ->
cytoplasm, nucleus
YMR086W NO SYMBOL FKH1
Main: biosynthesis (0.60) glutamate-ammonia ligase activity (0.20) cytoplasm (0.80) FKH1 (0.33)
Score: 0.40 0.00 0.60 0.067
P-value: 2.255E-01 (amino acid biosynthesis) 2.414E+00 (enzyme activity) 3.294E+00 (cytoplasm) 2.087E-01 (FKH1)

m_homeostasis_of_metal_ions_orfnum2SD_n20(1) AND m_RPE8(1) => SimExpr(YNL284C) OR SimExpr(other) : 5 1

m_glycolysis_and_gluconeogenesis_orfnum2SD_n4(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n17(1) => SimExpr(YNL284C) OR SimExpr(other) : 5 2

EXPR: (0.238) m_glycolysis_and_gluconeogenesis_orfnum2SD_n4 (P < 0.051) m_allantoin_and_allantoate_transporters_orfnum2SD_n17 (P < 0.034)

ORF SYMBOL P F C TF
YOR003W YSP3 protein catabolism ->
catabolism, protein metabolism peptidase activity ->
peptidase activity
YLR309C IMH1 vesicle-mediated transport ->
transport cytosol ->
cytoplasm DOT6
|YOR092W| ECM3 cell wall organization and biogenesis ->
cell organization and biogenesis ATPase activity ->
ATPase activity STE12, YAP1
|YGR239C| PEX21 protein-peroxisome targeting ->
cell organization and biogenesis, protein metabolism, transport protein binding, enzyme activator activity ->
protein binding, enzyme activator activity peroxisome, cytosol ->
cytoplasm MAL13, MET4, PUT3
YDR458C NO SYMBOL MATa1
YNL284C MRPL10 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex REB1, RTG1
YDR050C TPI1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism triose-phosphate isomerase activity ->
triose-phosphate isomerase activity cytosol, cytoplasm ->
cytoplasm GCR1, GCR2, HSF1, INO4, SIG1
Main: protein metabolism (0.50) peptidase activity (0.20) cytoplasm (1.00) GCR2 (0.17)
Score: 0.47 0.00 1.00 0.000
P-value: 1.263E+00 (catabolism) 2.014E+00 (hydrolase activity) 2.081E-01 (cytosol) 6.609E-01 (PUT3)

m_purine_and_pyrimidine_transporters_orfnum2SD_n17(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YMR056C) OR SimExpr(other) : 5 1

EXPR: (0.191) m_purine_and_pyrimidine_transporters_orfnum2SD_n17 (P < 0.001) m_amino-acid_transport_orfnum2SD_n18 (P < 0.000)

ORF SYMBOL P F C TF
YMR056C AAC1 ATP/ADP exchange ->
transport ATP/ADP antiporter activity ->
porter activity mitochondrial inner membrane ->
mitochondrion, inner membrane DAL81, NRG1, RCS1
|YOL014W| NO SYMBOL
YKR092C SRP40 nucleocytoplasmic transport ->
transport chaperone activity ->
chaperone activity nucleolus ->
nucleolus CUP9, MET4, RAP1
YKL029C MAE1 pyruvate metabolism, amino acid metabolism ->
amine metabolism, organic acid metabolism, amino acid and derivative metabolism malate dehydrogenase (oxaloacetate decarboxylating) activity ->
malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrion ->
mitochondrion ABF1, CIN5
YGR055W MUP1 sulfur amino acid transport ->
transport L-methionine porter activity ->
neutral amino acid transporter activity, amino acid transporter activity, polyamine transporter activity, porter activity integral to plasma membrane ->
integral to plasma membrane DAL81, INO4, MET4, STP1
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: transport (0.60) porter activity (0.50) mitochondrion (0.50) DAL81 (0.60)
Score: 0.30 0.17 0.17 0.500
P-value: 7.298E-01 (transport) 6.798E-03 (electrochemical potential-driven transporter activity) 1.269E+00 (mitochondrion) 1.545E-03 (DAL81)

m_g-proteins_orfnum2SD_n12(1) AND m_RPE8(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YMR056C) : 5

EXPR: (0.188) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_RPE8 (P < 0.001) m_cell_death_orfnum2SD_n8 (P < 0.001)

ORF SYMBOL P F C TF
YMR056C AAC1 ATP/ADP exchange ->
ATP/ADP exchange ATP/ADP antiporter activity ->
ATP/ADP antiporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane DAL81, NRG1, RCS1
YIL135C VHS2 G1/S transition of mitotic cell cycle ->
G1/S transition of mitotic cell cycle ABF1, DAL82, INO2, MAC1, MTH1, ROX1
YKR075C NO SYMBOL ABF1, IXR1, SFP1
YJL158C CIS3 cell wall organization and biogenesis ->
cell wall organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall, bud tip, endoplasmic reticulum, plasma membrane ->
cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YMR135C GID8 negative regulation of gluconeogenesis ->
negative regulation of gluconeogenesis ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: ATP/ADP exchange (0.25) structural constituent of cell wall (0.50) cytoplasm (1.00) ABF1 SWI4 SKN7 NDD1 ROX1 PHD1 DAL81 NRG1 (0.40)
Score: 0.00 0.00 1.00 0.400
P-value: 2.753E+00 (cell growth and/or maintenance) 2.000E+00 1.942E+00 (membrane) 6.415E-02 (DAL81)

m_RRSE3(1) AND PAC(1) AND mRRPE(1) => SimExpr(YLR276C) OR SimExpr(other) : 27 12

m_RRSE3(1) AND mRRPE(1) AND m_rRSE10(1) => SimExpr(YLR276C) OR SimExpr(other) : 6 2

EXPR: (0.176) mRRPE (P < 0.000) m_RRSE3 (P < 0.000) m_rRSE10 (P < 0.000)

ORF SYMBOL P F C TF
YPR010C RPA135 transcription from Pol I promoter ->
transcription from Pol I promoter DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosome assembly, ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus MATa1, RCS1, RTG3, SWI5
YNL110C NOP15 ribosomal large subunit biogenesis ->
ribosome biogenesis nucleus, nucleolus ->
nucleus
|YLR197W| SIK1 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex DAL81, HAL9
YNL132W KRE33
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis, snRNA processing, RNA processing, transcription from Pol I promoter RNA binding ->
RNA binding nucleolus ->
nucleus
|YKR059W| TIF1 translational initiation ->
translational initiation translation initiation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FKH1, FKH2
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
Main: ribosome biogenesis (0.71) RNA binding (0.60) nucleus (0.86) ABF1 (0.20)
Score: 0.67 0.30 0.76 0.000
P-value: 3.668E-05 (35S primary transcript processing) 1.798E-02 (ATP dependent RNA helicase activity) 7.399E-07 (nucleolus) 1.000E+00

m_organization_of_cell_wall_orfnum2SD_n14(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YNR074C) OR SimExpr(other) : 6 2

EXPR: (0.216) m_anion_transporters_orfnum2SD_n15 (P < 0.005) m_organization_of_cell_wall_orfnum2SD_n14 (P < 0.012)

ECB(1) AND m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) => SimExpr(YJL079C) OR SimExpr(other) : 5 2

EXPR: (0.241) m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5 (P < 0.013) ECB (P < 0.036)

m_g-proteins_orfnum2SD_n11(1) AND m_other_nutritional-response_activities_orfnum2SD_n10(1) AND mRRPE(1) => SimExpr(YLR328W) OR SimExpr(other) : 5 2

m_drug_transporters_orfnum2SD_n7(1) AND LYS14(1) => SimExpr(YLR328W) OR SimExpr(other) : 6 2

EXPR: (0.219) LYS14 (P < 0.003) m_drug_transporters_orfnum2SD_n7 (P < 0.002)

ORF SYMBOL P F C TF
|YNL097C| PHO23 chromatin modification ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleus ->
nucleus MAC1
YLR328W NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups CIN5, MSN1, ROX1
YOR348C PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
carboxylic acid transporter activity, polyamine transporter activity, electrochemical potential-driven transporter activity plasma membrane ->
plasma membrane SWI5
YOR346W REV1 DNA dependent DNA replication, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation DNA-directed DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups nucleus ->
nucleus
YPL087W YDC1 ceramide metabolism, response to heat ->
lipid metabolism, response to abiotic stimulus ceramidase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds endoplasmic reticulum ->
cytoplasm
YOL136C PFK27 fructose 2\,6-bisphosphate metabolism, regulation of glycolysis ->
alcohol metabolism, catabolism, carbohydrate metabolism, regulation of metabolism 6-phosphofructo-2-kinase activity ->
carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups cytoplasm ->
cytoplasm CBF1, RAP1
|YKL085W| MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.38) transferase activity\, transferring phosphorus-containing groups (0.43) cytoplasm (0.43) SWI5 (0.33)
Score: 0.14 0.14 0.29 0.067
P-value: 6.819E-01 (carbohydrate metabolism) 5.062E-02 (nucleotidyltransferase activity) 3.467E+00 (nucleus) 1.624E-01 (SWI5)

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND ECB(1) => SimExpr(YLR328W) OR SimExpr(other) : 5 2

m_other_pheromone_response_activities_orfnum2SD_n14(1) AND PAC(1) => SimExpr(YPR144C) OR SimExpr(other) : 6 2

EXPR: (0.219) PAC (P < 0.011) m_other_pheromone_response_activities_orfnum2SD_n14 (P < 0.001)

ORF SYMBOL P F C TF
YPR144C NOC4 ribosome biogenesis ->
cell organization and biogenesis nucleus ->
nucleus HIR1
YNL023C FAP1 transcription factor activity ->
DNA binding
YGL079W NO SYMBOL PHO4, STP1
YDR184C ATC1 response to stress, polar budding ->
response to stress, asexual reproduction nucleus ->
nucleus ARO80, GLN3, SIP4, SKO1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YIL066C RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
oxidoreductase activity\, acting on CH2 groups cytoplasm ->
cytoplasm RFX1, STB1
|YDR449C| UTP6 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
|YGR126W| NO SYMBOL CHA4, GTS1, SWI6
Main: cell organization and biogenesis (0.60) RNA binding (0.50) nucleus (0.80) HIR2 (0.17)
Score: 0.50 0.17 0.60 0.000
P-value: 5.981E-02 (ribosome biogenesis) 6.494E-01 (RNA binding) 2.441E-01 (nucleolus) 1.000E+00

m_other_energy_generation_activities_orfnum2SD_n9(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YIL070C) OR SimExpr(other) : 5 2

PAC(1) AND mRRPE(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YJL033W) OR SimExpr(other) : 5 2

EXPR: (0.194) mRRPE (P < 0.000) PAC (P < 0.002) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.000)

ORF SYMBOL P F C TF
YDR101C ARX1 ribosomal large subunit biogenesis ->
cell growth and/or maintenance nucleoplasm, cytoplasm ->
nucleus, cytoplasm IXR1, RFX1
YHR196W UTP9 processing of 20S pre-rRNA ->
cell growth and/or maintenance, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YDR184C ATC1 response to stress, polar budding ->
response to stress, cell growth and/or maintenance nucleus ->
nucleus ARO80, GLN3, SIP4, SKO1
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
|YLR222C| UTP13 processing of 20S pre-rRNA ->
cell growth and/or maintenance, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
YBR247C ENP1 processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance ->
cell growth and/or maintenance, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding nucleolus, nucleus ->
nucleus
YJL033W HCA4 35S primary transcript processing ->
cell growth and/or maintenance, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
Main: cell growth and/or maintenance (1.00) RNA binding (1.00) nucleus (1.00) ABF1 (0.20)
Score: 1.00 1.00 1.00 0.000
P-value: 4.211E-05 (ribosome biogenesis) 4.665E-05 (snoRNA binding) 6.933E-04 (nucleolus) 6.647E-01 (THI2)

ALPHA1(1) AND PAC(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YJL033W) OR SimExpr(other) : 5 1

EXPR: (0.203) PAC (P < 0.006) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YNL207W RIO2 processing of 20S pre-rRNA ->
rRNA processing nucleocytoplasmic transporter activity, protein kinase activity ->
nucleocytoplasmic transporter activity, transferase activity\, transferring phosphorus-containing groups cytosol, nucleus ->
cytoplasm, nucleus ABF1, MAL33
YNL299W TRF5 sister chromatid cohesion ->
sister chromatid cohesion DNA-directed DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups nucleus ->
nucleus
YHR196W UTP9 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
|YGR126W| NO SYMBOL CHA4, GTS1, SWI6
YJL033W HCA4 35S primary transcript processing ->
rRNA processing ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YPR137W RRP9 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
rRNA modification, rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, HIR1, RCS1
Main: rRNA processing (0.80) RNA binding (0.60) nucleus (1.00) ABF1 (0.50)
Score: 0.60 0.40 1.00 0.167
P-value: 2.188E-04 (rRNA processing) 5.596E-03 (snoRNA binding) 8.615E-03 (small nucleolar ribonucleoprotein complex) 2.978E-01 (MAL33)

SFF'(1) AND PAC(1) AND m_rRSE10(1) => SimExpr(YJL033W) OR SimExpr(other) : 9 3

PAC(1) AND ALPHA1'(1) AND m_rRSE10(1) => SimExpr(YJL033W) OR SimExpr(other) : 7 3

m_RRSE3(1) AND ALPHA1'(1) AND mRRPE(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YJL033W) OR SimExpr(other) : 5 1

EXPR: (0.182) mRRPE (P < 0.000) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) m_RRSE3 (P < 0.000) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
YNL132W KRE33
YNL075W IMP4 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription rRNA primary transcript binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex USV1
|YNL199C| GCR2 positive regulation of transcription from Pol II promoter, positive regulation of glycolysis ->
catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription, regulation of metabolism transcriptional activator activity ->
transcriptional activator activity nucleus ->
nucleus HIR1
YKL057C NUP120 mRNA-nucleus export, rRNA-nucleus export, snRNA-nucleus export, tRNA-nucleus export, NLS-bearing substrate-nucleus import, snRNP protein-nucleus import, mRNA-binding (hnRNP) protein-nucleus import, ribosomal protein-nucleus import, protein-nucleus export, nuclear pore organization and biogenesis ->
intracellular transport, intracellular protein transport, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transport structural molecule activity ->
structural molecule activity nuclear pore ->
nucleus, integral to membrane, endomembrane system GCR1
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YNL292W PUS4 tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00) RNA binding (0.40) nucleus (1.00) USV1 (0.40)
Score: 1.00 0.10 1.00 0.100
P-value: 2.767E-02 (RNA modification) 4.635E-01 (RNA binding) 1.363E-01 (nucleus) 8.097E-03 (USV1)

m_RRSE3(1) AND PAC(1) AND m_rRSE10(1) => SimExpr(YJL033W) OR SimExpr(other) : 7 3

m_RRSE3(1) AND PAC(1) AND mRRPE(1) AND m_rRSE10(1) => SimExpr(YJL033W) OR SimExpr(other) : 5 2

EXPR: (0.214) mRRPE (P < 0.000) m_RRSE3 (P < 0.000) m_rRSE10 (P < 0.001) PAC (P < 0.019)

ORF SYMBOL P F C TF
YPR010C RPA135 transcription from Pol I promoter ->
transcription from Pol I promoter DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleolus ROX1, SIG1
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosome assembly, ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus MATa1, RCS1, RTG3, SWI5
|YNL110C| NOP15 ribosomal large subunit biogenesis ->
ribosome biogenesis nucleus, nucleolus ->
nucleus, nucleolus
|YLR197W| SIK1 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
small nuclear ribonucleoprotein complex, nucleolus, nucleus, ribonucleoprotein complex DAL81, HAL9
YNL132W KRE33
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis, snRNA processing, RNA processing, transcription from Pol I promoter RNA binding ->
RNA binding nucleolus ->
nucleolus
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus HIR2, USV1
Main: ribosome biogenesis (0.83) RNA binding (0.75) nucleolus (1.00) HIR2 (0.25)
Score: 0.93 0.50 1.00 0.000
P-value: 1.851E-05 (35S primary transcript processing) 1.353E-02 (ATP dependent RNA helicase activity) 1.638E-07 (nucleolus) 7.291E-01 (USV1)

SFF'(1) AND m_RRSE3(1) AND PAC(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YJL033W) OR SimExpr(other) : 5 2

EXPR: (0.204) SFF' (P < 0.000) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) m_RRSE3 (P < 0.000) PAC (P < 0.008)

ORF SYMBOL P F C TF
|YPR149W| NCE102 protein secretion ->
protein secretion integral to membrane, endoplasmic reticulum, cytoplasm ->
integral to membrane, cytoplasm CIN5, FKH2, GRF10(Pho2), HSF1, NDD1, PUT3, RAP1, SKN7, SWI4, YAP6
|YHR052W| CIC1 protein catabolism ->
protein catabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YNL132W KRE33
YNL075W IMP4 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent rRNA primary transcript binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex USV1
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YNL292W PUS4 tRNA modification ->
RNA processing, tRNA metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
Main: RNA processing (0.60) RNA binding (0.50) nucleus (0.80) RCS1 USV1 (0.33)
Score: 0.30 0.17 0.80 0.133
P-value: 3.850E-02 (RNA modification) 6.158E-01 (RNA binding) 1.709E-02 (nucleolus) 4.279E-02 (USV1)

SFF(1) AND PAC(1) AND mRRPE(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YJL033W) OR SimExpr(other) : 5 2

EXPR: (0.191) SFF (P < 0.000) mRRPE (P < 0.000) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) PAC (P < 0.005)

ORF SYMBOL P F C TF
YGR145W ENP2
YJL069C UTP18 ABF1
|YHR052W| CIC1 protein catabolism ->
protein catabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleus HIR2, USV1
|YML125C| NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
YNL292W PUS4 tRNA modification ->
RNA processing, tRNA metabolism pseudouridylate synthase activity ->
pseudouridylate synthase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
Main: RNA processing (0.67) protein binding\, bridging (0.33) nucleus (1.00) ABF1 RCS1 (0.33)
Score: 0.33 0.00 1.00 0.133
P-value: 5.050E-01 (RNA processing) 2.769E+00 (binding) 2.194E-01 (nucleolus) 1.194E-01 (RCS1)

ALPHA1(1) AND SFF'(1) AND PAC(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YJL033W) OR SimExpr(other) : 6 2

EXPR: (0.219) SFF' (P < 0.000) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) PAC (P < 0.018) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YOL075C| NO SYMBOL CRZ1, DAL82, SIP4
YJL069C UTP18 ABF1
YNL075W IMP4 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter rRNA primary transcript binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleolus, small nuclear ribonucleoprotein complex, ribonucleoprotein complex USV1
YIR026C YVH1 meiosis, sporulation (sensu Saccharomyces) ->
nuclear division, sporulation (sensu Saccharomyces) protein tyrosine phosphatase activity ->
hydrolase activity\, acting on ester bonds DOT6, SUM1
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus HIR2, USV1
|YOR095C| RKI1 pentose-phosphate shunt ->
hexose catabolism, main pathways of carbohydrate metabolism, pyridine nucleotide metabolism, glucose metabolism ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity FHL1, FKH2, RAP1
YJL105W SET4 ASH1, CIN5, FKH1, MTH1, PHD1, SKN7
YNL163C RIA1 ribosome biogenesis ->
ribosome biogenesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding cytoplasm ->
cytoplasm FHL1, RAP1, YAP5
Main: ribosome biogenesis (0.60) RNA binding (0.40) nucleolus (0.67) RAP1 USV1 FHL1 (0.25)
Score: 0.30 0.10 0.33 0.071
P-value: 6.333E-02 (ribosome biogenesis) 9.092E-01 (RNA binding) 2.441E-01 (nucleolus) 5.370E-02 (USV1)

m_g-proteins_orfnum2SD_n13(1) AND m_anion_transporters_orfnum2SD_n22(1) => SimExpr(YPL186C) OR SimExpr(other) : 5 2

EXPR: (0.227) m_g-proteins_orfnum2SD_n13 (P < 0.001) m_anion_transporters_orfnum2SD_n22 (P < 0.000)

ORF SYMBOL P F C TF
|YGR060W| ERG25 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
YPL186C UIP4 nuclear membrane ->
nucleus, endomembrane system RIM101, USV1
|YMR139W| RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MAL33, YJL206C
YNR006W VPS27 protein-Golgi retention ->
cell organization and biogenesis, protein metabolism, transport protein binding ->
protein binding endosome ->
cytoplasm ARO80, CHA4, DOT6, GLN3, HAP3
YNL065W AQR1 drug transport, monocarboxylic acid transport ->
transport, organic acid transport, response to abiotic stimulus monocarboxylic acid transporter activity, drug transporter activity ->
monocarboxylic acid transporter activity, drug transporter activity plasma membrane ->
plasma membrane MET4
YGL058W RAD6 DNA repair, ubiquitin-dependent protein catabolism, protein monoubiquitination, histone ubiquitination ->
catabolism, nuclear organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ubiquitin conjugating enzyme activity ->
ubiquitin conjugating enzyme activity nucleus, cytoplasm, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm, endoplasmic reticulum PHO4
YPL270W MDL2 aerobic respiration ->
energy pathways ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane HAP4
Main: protein metabolism (0.50) ubiquitin conjugating enzyme activity (0.17) cytoplasm (0.67) MET4 (0.29)
Score: 0.27 0.00 0.60 0.048
P-value: 3.226E-01 (proteolysis and peptidolysis) 9.633E-01 (transporter activity) 5.258E-01 (membrane) 7.863E-02 (MET4)

m_lipid_and_fatty-acid_binding_orfnum2SD_n13(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) => SimExpr(YLR378C) OR SimExpr(other) : 6 2

EXPR: (0.228) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.003) m_lipid_and_fatty-acid_binding_orfnum2SD_n13 (P < 0.004)

ORF SYMBOL P F C TF
YMR005W TAF4 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase II transcription factor activity ->
RNA polymerase II transcription factor activity transcription factor TFIID complex ->
nucleus ABF1, GRF10(Pho2)
YKL160W ELF1 cell growth ->
cell growth
YGL108C NO SYMBOL DAL82, MAL13, SWI5, YAP5
|YNL101W| AVT4 neutral amino acid transport ->
transport neutral amino acid transporter activity ->
neutral amino acid transporter activity vacuole ->
cytoplasm HAP3, INO4, IXR1, PHD1, RAP1
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YHR208W BAT1 branched chain family amino acid biosynthesis, amino acid catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis, catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity mitochondrial matrix ->
cytoplasm LEU3, PHO4
|YGL100W| SEH1 mRNA-nucleus export, rRNA-nucleus export, snRNA-nucleus export, tRNA-nucleus export, NLS-bearing substrate-nucleus import, snRNP protein-nucleus import, mRNA-binding (hnRNP) protein-nucleus import, ribosomal protein-nucleus import, protein-nucleus export, nuclear pore organization and biogenesis ->
intracellular transport, intracellular protein transport, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transport structural molecule activity ->
structural molecule activity nuclear pore ->
nucleus, integral to membrane, endomembrane system FHL1, HMS1, SFP1
YNL231C PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
Main: transport (0.57) protein transporter activity (0.17) cytoplasm (0.67) MAL13 (0.29)
Score: 0.38 0.00 0.53 0.048
P-value: 9.022E-01 (transport) 1.690E-01 (transporter activity) 6.913E-01 (endomembrane system) 7.304E-02 (MAL13)

m_metal_ion_transporters_orfnum2SD_n26(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YOL122C) OR SimExpr(other) : 7 3

EXPR: (0.243) m_metal_ion_transporters_orfnum2SD_n26 (P < 0.012) m_anion_transporters_orfnum2SD_n20 (P < 0.062)

m_glyoxylate_cycle_orfnum2SD_n11(1) AND m_g-proteins_orfnum2SD_n11(1) AND m_MERE11(1) => SimExpr(YOL122C) OR SimExpr(other) : 5 2

EXPR: (0.212) m_g-proteins_orfnum2SD_n11 (P < 0.006) m_MERE11 (P < 0.010) m_glyoxylate_cycle_orfnum2SD_n11 (P < 0.003)

ORF SYMBOL P F C TF
|YOR274W| MOD5 tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism tRNA isopentenyltransferase activity ->
tRNA isopentenyltransferase activity nucleus, nucleolus, mitochondrion, cytosol ->
nucleus, mitochondrion, cytoplasm ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YJL036W SNX4 autophagy, transport ->
autophagy, transport lipid binding ->
lipid binding membrane ->
membrane FKH2
|YGR088W| CTT1 response to stress ->
response to stress catalase activity ->
catalase activity cytoplasm ->
cytoplasm
YOL122C SMF1 manganese ion transport ->
transport manganese ion transporter activity ->
manganese ion transporter activity plasma membrane, vacuole (sensu Fungi) ->
membrane, cytoplasm
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YMR291W NO SYMBOL RAP1
YDR019C GCV1 one-carbon compound metabolism, glycine metabolism ->
one-carbon compound metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism glycine dehydrogenase (decarboxylating) activity ->
glycine dehydrogenase (decarboxylating) activity mitochondrion ->
cytoplasm BAS1
Main: amino acid and derivative metabolism (0.33) manganese ion transporter activity (0.17) cytoplasm (0.83) BAS1 (0.40)
Score: 0.13 0.00 0.73 0.100
P-value: 3.574E-01 (amino acid metabolism) 3.837E-01 (oxidoreductase activity) 1.448E+00 (cytosol) 9.248E-02 (BAS1)

m_ion_transporters_orfnum2SD_n3(1) AND m_amino-acid_transporters_orfnum2SD_n11(1) => SimExpr(YOL122C) OR SimExpr(other) : 6 2

m_g-proteins_orfnum2SD_n11(1) AND m_peroxisomal_transport_orfnum2SD_n19(1) => SimExpr(YOL122C) OR SimExpr(other) : 6 2

m_lipid_and_fatty-acid_binding_orfnum2SD_n13(1) AND PDR(1) => SimExpr(YIL045W) OR SimExpr(other) : 5 1

EXPR: (0.213) m_lipid_and_fatty-acid_binding_orfnum2SD_n13 (P < 0.002) PDR (P < 0.003)

ORF SYMBOL P F C TF
YOR354C MSC6 meiotic recombination ->
meiotic recombination ABF1, FHL1, GAT1
|YFR022W| NO SYMBOL
YFR007W NO SYMBOL GLN3, PDR1, RFX1, RLM1, STE12
YAL061W NO SYMBOL
YIL045W PIG2 protein phosphatase regulator activity ->
protein phosphatase regulator activity CIN5
YNL231C PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
phospholipid transport, sterol biosynthesis, response to drug phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
Main: meiotic recombination (0.50) protein phosphatase regulator activity (0.50) cytoplasm (1.00) ABF1 (0.25)
Score: 0.00 0.00 0.00 0.000
P-value: 5.486E+00 (cell growth and/or maintenance) 2.000E+00 0.000E+00 5.601E-01 (GAT1)

m_g-proteins_orfnum2SD_n11(1) AND m_other_nutritional-response_activities_orfnum2SD_n10(1) AND mRRPE(1) => SimExpr(YPR194C) OR SimExpr(other) : 5 2

m_phosphate_transport_orfnum2SD_n18(1) AND m_phosphate_metabolism_orfnum2SD_n16(1) => SimExpr(YOR343C) OR SimExpr(other) : 5 2

mRRPE(1) AND m_c-compound_carbohydrate_transport_orfnum2SD_n11(1) => SimExpr(YLR372W) OR SimExpr(other) : 5 1

EXPR: (0.182) m_c-compound_carbohydrate_transport_orfnum2SD_n11 (P < 0.003) mRRPE (P < 0.000)

ORF SYMBOL P F C TF
YDR341C NO SYMBOL GCN4, ZMS1
YGL105W ARC1 tRNA-nucleus export, amino acid activation ->
transport, biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism tRNA binding ->
tRNA binding cytoplasm, methionyl glutamyl tRNA synthetase complex ->
cytoplasm, methionyl glutamyl tRNA synthetase complex
YLR372W SUR4 fatty acid biosynthesis, post-Golgi transport, sphingolipid biosynthesis, fatty acid elongation ->
transport, lipid metabolism, biosynthesis, vesicle-mediated transport, organic acid metabolism fatty acid elongase activity ->
acyltransferase activity endoplasmic reticulum membrane, endoplasmic reticulum ->
cytoplasm, endomembrane system SRD1
YOL120C RPL18A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MAL13, RAP1, YAP5
YLR293C GSP1 nucleocytoplasmic transport, nuclear organization and biogenesis, rRNA processing ->
transport, cell organization and biogenesis, RNA metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RAN small monomeric GTPase activity ->
GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides cytoplasm, nucleus ->
cytoplasm, nucleus ABF1
|YDR040C| ENA1 sodium ion transport ->
transport P-type ATPase activity ->
ATP binding, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane NRG1, SOK2
Main: transport (0.80) hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides (0.40) cytoplasm (0.80) ABF1 (0.20)
Score: 0.80 0.10 0.60 0.000
P-value: 1.334E-01 (nucleocytoplasmic transport) 5.807E-01 (hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides) 2.499E+00 (membrane) 4.060E-01 (ZMS1)

SWI5(1) AND m_ion_transporters_orfnum2SD_n14(1) AND SCB(1) => SimExpr(YPL232W) OR SimExpr(other) : 6 2

EXPR: (0.235) SWI5 (P < 0.000) m_ion_transporters_orfnum2SD_n14 (P < 0.005) SCB (P < 0.000)

ALPHA1(1) AND MCB(1) => SimExpr(YFR027W) OR SimExpr(other) : 23 9

MCB(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n8(1) => SimExpr(YFR027W) OR SimExpr(other) : 6 1

m_amino-acid_degradation_orfnum2SD_n27(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YHR208W) OR SimExpr(other) : 7 2

EXPR: (0.201) m_amino-acid_degradation_orfnum2SD_n27 (P < 0.003) m_cell_death_orfnum2SD_n8 (P < 0.003)

ORF SYMBOL P F C TF
|YML054C| CYB2 electron transport ->
electron transport L-lactate dehydrogenase (cytochrome) activity ->
L-lactate dehydrogenase (cytochrome) activity mitochondrial intermembrane space ->
cytoplasm
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YDR462W MRPL28 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex ABF1
YOR312C RPL20B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, FKH2, GAT3, RAP1
YHR208W BAT1 branched chain family amino acid biosynthesis, amino acid catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis, catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity mitochondrial matrix ->
cytoplasm LEU3, PHO4
|YGR180C| RNR4 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity nucleus, cytoplasm ->
nucleus, cytoplasm CIN5, MBP1, RAP1, RFX1, SWI6
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
YOR130C ORT1 arginine biosynthesis, nuclear migration (sensu Saccharomyces) ->
amine metabolism, cell organization and biogenesis, cell proliferation, cell cycle, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ornithine transporter activity ->
ornithine transporter activity mitochondrial membrane ->
cytoplasm GCN4
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: biosynthesis (0.67) structural constituent of ribosome (0.25) cytoplasm (0.86) RAP1 (0.38)
Score: 0.47 0.04 0.71 0.214
P-value: 3.320E-02 (amino acid biosynthesis) 6.287E-01 (structural constituent of ribosome) 2.364E-01 (mitochondrion) 2.349E-01 (GCN4)

m_amino-acid_degradation_orfnum2SD_n27(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn(1) => SimExpr(YHR208W) OR SimExpr(other) : 8 3

EXPR: (0.227) m_amino-acid_degradation_orfnum2SD_n27 (P < 0.005) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn (P < 0.005)

ORF SYMBOL P F C TF
|YML054C| CYB2 electron transport ->
electron transport L-lactate dehydrogenase (cytochrome) activity ->
L-lactate dehydrogenase (cytochrome) activity mitochondrial intermembrane space ->
cytoplasm
YPR145W ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YOL012C HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
|YOL014W| NO SYMBOL
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
|YGL055W| OLE1 mitochondrion inheritance, fatty acid desaturation ->
cell organization and biogenesis, lipid metabolism, organic acid metabolism stearoyl-CoA desaturase activity ->
stearoyl-CoA desaturase activity endoplasmic reticulum membrane ->
cytoplasm, endomembrane system HSF1
YHR208W BAT1 branched chain family amino acid biosynthesis, amino acid catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis, catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity mitochondrial matrix ->
cytoplasm LEU3, PHO4
YDR019C GCV1 one-carbon compound metabolism, glycine metabolism ->
one-carbon compound metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism glycine dehydrogenase (decarboxylating) activity ->
glycine dehydrogenase (decarboxylating) activity mitochondrion ->
cytoplasm BAS1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: cell organization and biogenesis (0.40) stearoyl-CoA desaturase activity (0.11) cytoplasm (0.67) SWI4 SKN7 NDD1 DAL81 (0.25)
Score: 0.40 0.00 0.40 0.143
P-value: 7.450E-02 (organic acid metabolism) 2.799E-01 (oxidoreductase activity) 1.172E+00 (mitochondrion) 3.305E-01 (DAL81)

m_RPE57(1) AND m_cell_death_orfnum2SD_n8(1) => SimExpr(YHR208W) OR SimExpr(other) : 7 3

m_RPE57(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn(1) => SimExpr(YHR208W) : 5

EXPR: (0.151) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n12.scn (P < 0.000) m_RPE57 (P < 0.008)

ndt80(MSE)(1) AND mRRPE(1) => SimExpr(YFR023W) OR SimExpr(other) : 5 2

EXPR: (0.195) mRRPE (P < 0.000) ndt80(MSE) (P < 0.030)

ORF SYMBOL P F C TF
YHR184W SSP1 spore wall assembly (sensu Saccharomyces), protein complex assembly ->
protein metabolism, sporulation prospore membrane ->
prospore SUM1
YOR339C UBC11 protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism ubiquitin conjugating enzyme activity ->
ubiquitin conjugating enzyme activity cytoplasm ->
cytoplasm HAP2, IXR1
|YJR007W| SUI2 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex GLN3, HAP3, HIR1, RCS1
YOR338W NO SYMBOL RAP1
YOL091W SPO21 spore wall assembly (sensu Saccharomyces), meiosis ->
cell proliferation, sporulation structural molecule activity ->
structural molecule activity spindle pole body ->
cytoplasm HAP5, SUM1
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
|YGL253W| HXK2 fructose metabolism ->
alcohol metabolism, carbohydrate metabolism hexokinase activity ->
hexokinase activity nucleus, cytosol ->
nucleus, cytoplasm ABF1, CIN5, HSF1, SWI4
Main: protein metabolism (0.50) ubiquitin conjugating enzyme activity (0.25) cytoplasm (0.80) SUM1 (0.43)
Score: 0.33 0.00 0.60 0.190
P-value: 1.686E-02 (spore wall assembly (sensu Saccharomyces)) 2.849E+00 (enzyme activity) 3.294E+00 (cytoplasm) 4.371E-03 (SUM1)

PDR(1) AND m_fermentation_orfnum2SD_n14(1) => SimExpr(YDR380W) OR SimExpr(other) : 5 2

MCB(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n8(1) => SimExpr(YNL039W) OR SimExpr(other) : 5 2

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND m_trna_processing_orfnum2SD_n6(1) => SimExpr(YML057W) OR SimExpr(other) : 7 2

EXPR: (0.225) m_metabolism_of_energy_reserves_orfnum2SD_n8 (P < 0.006) m_trna_processing_orfnum2SD_n6 (P < 0.000)

ORF SYMBOL P F C TF
YMR083W ADH3 fermentation ->
energy pathways alcohol dehydrogenase activity ->
alcohol dehydrogenase activity mitochondrial matrix, soluble fraction ->
cytoplasm, soluble fraction RAP1
YLR258W GSY2 glycogen metabolism ->
carbohydrate metabolism, energy pathways glycogen (starch) synthase activity ->
glycogen (starch) synthase activity cytoplasm ->
cytoplasm
YOL089C HAL9 salinity response, transcription initiation from Pol II promoter ->
response to abiotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus DOT6, RGT1, SFL1, SIP4
YNL208W NO SYMBOL INO2
YML057W CMP2 cell ion homeostasis, adaptation to pheromone during conjugation with cellular fusion ->
cell homeostasis, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus calcium-dependent protein serine/threonine phosphatase activity ->
calcium-dependent protein serine/threonine phosphatase activity cytoplasm ->
cytoplasm MSN4
|YNL065W| AQR1 drug transport, monocarboxylic acid transport ->
transport, organic acid transport, response to abiotic stimulus monocarboxylic acid transporter activity, drug transporter activity ->
monocarboxylic acid transporter activity, drug transporter activity plasma membrane ->
plasma membrane MET4
YKL141W SDH3 oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways succinate dehydrogenase activity ->
succinate dehydrogenase activity respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
|YMR108W| ILV2 branched chain family amino acid biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis acetolactate synthase activity ->
acetolactate synthase activity mitochondrion ->
cytoplasm HSF1, LEU3
YPR014C NO SYMBOL CIN5, MAL13, PHD1
Main: response to abiotic stimulus (0.43) drug transporter activity (0.14) cytoplasm (0.71) SFL1 (0.14)
Score: 0.29 0.00 0.48 0.000
P-value: 8.396E-02 (energy pathways) 5.952E-01 (oxidoreductase activity) 7.252E-01 (mitochondrion) 1.000E+00

m_metal_ion_transporters_orfnum2SD_n17(1) AND m_other_energy_generation_activities_orfnum2SD_n22(1) => SimExpr(YML057W) OR SimExpr(other) : 5 2

m_drug_transporters_orfnum2SD_n14(1) AND m_metal_ion_transporters_orfnum2SD_n25(1) => SimExpr(YLR206W) OR SimExpr(other) : 5 1

EXPR: (0.224) m_drug_transporters_orfnum2SD_n14 (P < 0.029) m_metal_ion_transporters_orfnum2SD_n25 (P < 0.002)

ORF SYMBOL P F C TF
YKL149C DBR1 RNA catabolism, snoRNA metabolism ->
catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA lariat debranching enzyme activity ->
hydrolase activity\, acting on ester bonds, RNA binding nucleus ->
nucleus
YLR206W ENT2 actin cortical patch assembly, endocytosis, actin filament organization ->
transport, cell organization and biogenesis cytoskeletal adaptor activity ->
cytoskeletal protein binding actin cortical patch (sensu Saccharomyces) ->
cell cortex, cytoplasm MAL13, PHO4, SKN7
|YIL120W| QDR1 multidrug transport ->
transport, response to abiotic stimulus multidrug transporter activity ->
multidrug transporter activity plasma membrane, integral to plasma membrane ->
plasma membrane, integral to membrane PHD1, SIP4
YJR060W CBF1 methionine biosynthesis, DNA replication and chromosome cycle ->
cell proliferation, amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism DNA binding, centromeric DNA binding ->
DNA binding nucleus ->
nucleus CBF1
YMR136W GAT2 transcription ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity ->
DNA binding nucleus ->
nucleus ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
YDL092W SRP14 protein-ER targeting ->
cell organization and biogenesis, protein metabolism, transport signal sequence binding ->
signal sequence binding signal recognition particle ->
cytoplasm ABF1, PHD1, RPH1
Main: transport (0.50) DNA binding (0.33) nucleus (0.50) PHD1 (0.60)
Score: 0.27 0.07 0.27 0.400
P-value: 1.147E+00 (transport) 6.296E-02 (binding) 2.143E+00 (nucleus) 9.037E-03 (PHD1)

m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n17(1) => SimExpr(YLR206W) OR SimExpr(other) : 6 3

EXPR: (0.240) m_biogenesis_of_chromosome_structure_orfnum2SD_n9 (P < 0.005) m_allantoin_and_allantoate_transporters_orfnum2SD_n17 (P < 0.014)

ORF SYMBOL P F C TF
|YGR236C| SPG1
YPR022C NO SYMBOL
YLR206W ENT2 actin cortical patch assembly, endocytosis, actin filament organization ->
transport, cell organization and biogenesis cytoskeletal adaptor activity ->
cytoskeletal adaptor activity actin cortical patch (sensu Saccharomyces) ->
cell cortex, cytoskeleton MAL13, PHO4, SKN7
|YPR008W| HAA1 transcription initiation from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus
YDR046C BAP3 amino acid transport ->
transport amino acid transporter activity ->
amino acid transporter activity plasma membrane ->
plasma membrane DAL81, STP1
YJR137C ECM17 sulfate assimilation, cell wall organization and biogenesis ->
sulfur metabolism, cell organization and biogenesis sulfite reductase (NADPH) activity ->
sulfite reductase (NADPH) activity ABF1, DOT6, GCR2, MET31, REB1
|YHR172W| SPC97 microtubule nucleation ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton inner plaque of spindle pole body, outer plaque of spindle pole body ->
cytoskeleton, microtubule organizing center
YNR051C BRE5
YGR108W CLB1 regulation of CDK activity, meiotic G2/MI transition, G2/M transition of mitotic cell cycle, mitotic spindle assembly (sensu Saccharomyces) ->
cytoplasm organization and biogenesis, cell cycle cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity CIN5, CUP9, SKN7, SOK2
Main: cell organization and biogenesis (0.50) cyclin-dependent protein kinase\, regulator activity (0.17) cytoskeleton (0.50) SKN7 (0.50)
Score: 0.27 0.00 0.17 0.167
P-value: 1.846E-01 (cytoskeleton organization and biogenesis) 1.136E+00 (transporter activity) 5.517E-01 (cytoskeleton) 5.451E-01 (SKN7)

m_lipid_and_fatty-acid_transport_orfnum2SD_n7(1) AND STRE'(1) => SimExpr(YML117W) OR SimExpr(other) : 5 1

EXPR: (0.206) m_lipid_and_fatty-acid_transport_orfnum2SD_n7 (P < 0.001) STRE' (P < 0.007)

ORF SYMBOL P F C TF
YKR095W MLP1 protein-nucleus import ->
protein metabolism, transport nuclear membrane, nucleoplasm ->
nucleus, endomembrane system FHL1, RAP1
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
|YGR067C| NO SYMBOL ABF1, ASH1, RGM1
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
amine metabolism, alcohol metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity mitochondrion ->
cytoplasm
YPL203W TPK2 protein amino acid phosphorylation, pseudohyphal growth, RAS protein signal transduction ->
phosphorus metabolism, cell organization and biogenesis, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex
YML117W NAB6
Main: alcohol metabolism (0.50) cAMP-dependent protein kinase activity (0.33) cytoplasm (0.75) ABF1 (0.33)
Score: 0.33 0.00 0.50 0.000
P-value: 4.493E-02 (water-soluble vitamin metabolism) 9.703E-01 (transferase activity) 3.918E+00 (cytoplasm) 5.198E-01 (ADR1)

m_allantoin_and_allantoate_transporters_orfnum2SD_n7(1) AND MCM1'(1) AND m_phosphate_transport_orfnum2SD_n13(1) => SimExpr(YNL185C) OR SimExpr(other) : 5 2

EXPR: (0.227) m_phosphate_transport_orfnum2SD_n13 (P < 0.005) m_allantoin_and_allantoate_transporters_orfnum2SD_n7 (P < 0.002) MCM1' (P < 0.002)

ORF SYMBOL P F C TF
YOR086C NO SYMBOL ABF1, STE12
|YML005W| NO SYMBOL USV1
YDR380W ARO10 leucine catabolism ->
amine catabolism, amino acid metabolism carboxy-lyase activity, pyruvate decarboxylase activity ->
carboxy-lyase activity, pyruvate decarboxylase activity ARO80, MTH1
|YOL163W| NO SYMBOL
YOL122C SMF1 manganese ion transport ->
cation transport manganese ion transporter activity ->
manganese ion transporter activity plasma membrane, vacuole (sensu Fungi) ->
plasma membrane, cytoplasm
YNL185C MRPL19 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex
YOL023W IFM1 translational initiation ->
protein biosynthesis translation initiation factor activity, RNA binding, GTPase activity ->
translation initiation factor activity, RNA binding, GTPase activity mitochondrion ->
cytoplasm BAS1, FKH1, FKH2, GCR2, HAP3, REB1, STP1, SUM1, YFL044C
Main: protein biosynthesis (0.50) RNA binding (0.25) cytoplasm (1.00) GCR2 (0.25)
Score: 0.17 0.00 1.00 0.000
P-value: 1.533E+00 (protein biosynthesis) 2.849E+00 (enzyme activity) 1.397E+00 (mitochondrion) 1.000E+00

m_LFTE17(1) AND m_chromatin_modification_orfnum2SD_n21(1) => SimExpr(YJR150C) OR SimExpr(other) : 5 2

EXPR: (0.225) m_LFTE17 (P < 0.002) m_chromatin_modification_orfnum2SD_n21 (P < 0.002)

ORF SYMBOL P F C TF
YJR150C DAN1 sterol transport ->
sterol transport cell wall (sensu Fungi) ->
cell wall (sensu Fungi) PHO4
YOR107W RGS2 G-protein signaling\, coupled to cAMP nucleotide second messenger ->
G-protein signaling\, coupled to cAMP nucleotide second messenger GTPase activator activity ->
GTPase activator activity PHD1, RAP1
|YHR097C| NO SYMBOL
YKL162C NO SYMBOL DOT6, RTG1
YLR357W RSC2 chromatin modeling ->
chromatin modeling nucleosome remodeling complex ->
nucleosome remodeling complex
YIL083C NO SYMBOL DIG1, STE12
|YHR073W| OSH3 steroid biosynthesis ->
steroid biosynthesis oxysterol binding ->
oxysterol binding cytoplasm ->
cytoplasm DAL82
Main: sterol transport (0.25) oxysterol binding (0.50) cytoplasm (0.33) RAP1 (0.20)
Score: 0.00 0.00 0.00 0.000
P-value: 5.122E+00 (cellular process) 2.000E+00 4.000E+00 (intracellular) 5.833E-01 (DAL82)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_LFTE17(1) AND m_chromatin_modification_orfnum2SD_n21(1) => SimExpr(YJR150C) : 5

EXPR: (0.187) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) m_LFTE17 (P < 0.000) m_chromatin_modification_orfnum2SD_n21 (P < 0.000)

ORF SYMBOL P F C TF
YJR150C DAN1 sterol transport ->
sterol transport cell wall (sensu Fungi) ->
cell wall (sensu Fungi) PHO4
YOR107W RGS2 G-protein signaling\, coupled to cAMP nucleotide second messenger ->
G-protein signaling\, coupled to cAMP nucleotide second messenger GTPase activator activity ->
GTPase activator activity PHD1, RAP1
YKL162C NO SYMBOL DOT6, RTG1
YLR357W RSC2 chromatin modeling ->
chromatin modeling nucleosome remodeling complex ->
nucleosome remodeling complex
YIL083C NO SYMBOL DIG1, STE12
Main: sterol transport (0.33) GTPase activator activity (1.00) cell wall (sensu Fungi) (0.50) RAP1 (0.25)
Score: 0.00 0.00 0.00 0.000
P-value: 3.009E+00 (cellular process) 0.000E+00 3.000E+00 (cell) 5.395E-01 (DIG1)

BAS1(1) AND m_detoxificaton_orfnum2SD_n39(1) => SimExpr(YLR398C) OR SimExpr(other) : 5 2

BAS1(1) AND CSRE(1) AND m_lipid_transporters_orfnum2SD_n8(1) => SimExpr(YLR398C) : 5

EXPR: (0.177) CSRE (P < 0.000) BAS1 (P < 0.000) m_lipid_transporters_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YLR328W NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity CIN5, MSN1, ROX1
YMR272C SCS7 fatty acid metabolism ->
lipid metabolism, organic acid metabolism oxidoreductase activity ->
oxidoreductase activity endoplasmic reticulum ->
cytoplasm IXR1, SUM1
YLR398C SKI2 mRNA catabolism, regulation of translation ->
catabolism, biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism RNA helicase activity, translation repressor activity ->
RNA helicase activity, translation repressor activity cytoplasm ->
cytoplasm MTH1
YLR229C CDC42 exocytosis, apical bud growth, isotropic bud growth, pseudohyphal growth, invasive growth, Rho protein signal transduction, signal transduction during conjugation with cellular fusion, establishment of cell polarity (sensu Saccharomyces) ->
transport, asexual reproduction, cellular morphogenesis, signal transduction, conjugation with cellular fusion, cell organization and biogenesis, perception of external stimulus, vesicle-mediated transport, response to abiotic stimulus Rho small monomeric GTPase activity, signal transducer activity ->
GTP binding, signal transducer activity, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides soluble fraction, plasma membrane, bud tip, bud neck, shmoo tip ->
soluble fraction, plasma membrane, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces) ABF1, FZF1, INO2, RTS2
YOR153W PDR5 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
ATP binding, multidrug transporter activity, P-P-bond-hydrolysis-driven transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane YAP6
Main: response to abiotic stimulus (0.40) hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides (0.40) cytoplasm (0.50) ABF1 (0.20)
Score: 0.10 0.10 0.33 0.000
P-value: 2.028E-01 (response to abiotic stimulus) 3.381E-01 (enzyme activity) 2.555E-01 (plasma membrane) 2.345E-01 (MSN1)

m_allantoin_and_allantoate_transporters_orfnum2SD_n7(1) AND m_ionic_homeostasis_orfnum2SD_n6(1) => SimExpr(YNL229C) OR SimExpr(other) : 11 4

EXPR: (0.229) m_ionic_homeostasis_orfnum2SD_n6 (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n7 (P < 0.000)

ORF SYMBOL P F C TF
YGR060W ERG25 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
YOR323C PRO2 proline biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis glutamate-5-semialdehyde dehydrogenase activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm PDR1
|YPL163C| SVS1 response to chemical substance ->
response to abiotic stimulus SWI4, SWI6
YKL116C PRR1 MAPKKK cascade ->
signal transduction receptor signaling protein serine/threonine kinase activity ->
phosphotransferase activity\, alcohol group as acceptor
YIL167W NO SYMBOL
YFL039C ACT1 cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter ->
transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex ->
cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex DIG1, ROX1, STE12
YML057W CMP2 cell ion homeostasis, adaptation to pheromone during conjugation with cellular fusion ->
cell homeostasis, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus calcium-dependent protein serine/threonine phosphatase activity ->
phosphoric ester hydrolase activity cytoplasm ->
cytoplasm MSN4
YGL001C ERG26 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity ->
C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity endoplasmic reticulum, endoplasmic reticulum membrane ->
cytoplasm, endomembrane system ARG80, ARO80, AZF1, CUP9, HAL9, HAP4, HAP5, HIR2, HMS1, PDR1, RTG1, RTG3, YFL044C
YDR003W NO SYMBOL ARG80, FKH1, GCR2, GLN3
YJL155C FBP26 gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, biosynthesis, energy pathways fructose-2\,6-bisphosphate 2-phosphatase activity, 6-phosphofructo-2-kinase activity ->
phosphoric ester hydrolase activity, carbohydrate kinase activity, phosphotransferase activity\, alcohol group as acceptor cytosol ->
cytoplasm GTS1, MCM1
YNL229C URE2 regulation of nitrogen utilization ->
nitrogen metabolism transcription co-repressor activity ->
transcription cofactor activity soluble fraction ->
soluble fraction SWI4
|YKL217W| JEN1 lactate transport ->
transport lactate transporter activity ->
organic anion transporter activity, carboxylic acid transporter activity plasma membrane ->
plasma membrane BAS1
|YKL104C| GFA1 cell wall chitin biosynthesis ->
cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity ->
transaminase activity REB1
|YDR437W| NO SYMBOL
YMR319C FET4 low affinity iron ion transport, intracellular copper ion transport ->
transport iron ion transporter activity ->
di-\, tri-valent inorganic cation transporter activity, transition metal ion transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane AZF1, CIN5, INO4, MAC1, NRG1, PHD1, RCS1, ROX1, SFL1, SOK2, YAP6
Main: biosynthesis (0.42) phosphotransferase activity\, alcohol group as acceptor (0.18) cytoplasm (0.67) SWI4 ARG80 AZF1 PDR1 ROX1 (0.17)
Score: 0.23 0.04 0.50 0.076
P-value: 8.133E-02 (ergosterol biosynthesis) 1.182E+00 (phosphoric monoester hydrolase activity) 6.484E-01 (endoplasmic reticulum membrane) 5.698E-01 (AZF1)

m_allantoin_and_allantoate_transporters_orfnum2SD_n7(1) AND m_other_nutritional-response_activities_orfnum2SD_n10(1) AND m_ionic_homeostasis_orfnum2SD_n6(1) => SimExpr(YNL229C) OR SimExpr(other) : 5 1

EXPR: (0.205) m_ionic_homeostasis_orfnum2SD_n6 (P < 0.002) m_other_nutritional-response_activities_orfnum2SD_n10 (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n7 (P < 0.004)

ORF SYMBOL P F C TF
YOR323C PRO2 proline biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis glutamate-5-semialdehyde dehydrogenase activity ->
glutamate-5-semialdehyde dehydrogenase activity cytoplasm ->
cytoplasm PDR1
YKL116C PRR1 MAPKKK cascade ->
signal transduction receptor signaling protein serine/threonine kinase activity ->
receptor signaling protein serine/threonine kinase activity
YIL167W NO SYMBOL
YFL039C ACT1 cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter ->
transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex ->
cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex DIG1, ROX1, STE12
YNL229C URE2 regulation of nitrogen utilization ->
nitrogen metabolism transcription co-repressor activity ->
transcription co-repressor activity soluble fraction ->
soluble fraction SWI4
|YKL104C| GFA1 cell wall chitin biosynthesis ->
cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity ->
glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity REB1
Main: cell organization and biogenesis (0.40) transcription co-repressor activity (0.20) cytoplasm (0.67) SWI4 (0.25)
Score: 0.20 0.00 0.33 0.000
P-value: 2.184E-01 (external encapsulating structure organization and biogenesis) 9.703E-01 (transferase activity) 4.731E+00 (cytoplasm) 5.507E-01 (DIG1)

m_other_proteolytic_degradation_orfnum2SD_n12(1) AND m_mitochondrial_biogenesis_orfnum2SD_n5(1) => SimExpr(YOR198C) OR SimExpr(other) : 5 1

m_deoxyribonucleotide_metabolism_orfnum2SD_n10(1) AND ALPHA1(1) AND m_ion_transporters_orfnum2SD_n3(1) => SimExpr(YDR493W) OR SimExpr(other) : 6 2

EXPR: (0.204) ALPHA1 (P < 0.000) m_deoxyribonucleotide_metabolism_orfnum2SD_n10 (P < 0.000) m_ion_transporters_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
YIL121W QDR2 PHO4, RAP1, SWI4
|YOR348C| PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid permease activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YDR493W NO SYMBOL ARG81, MIG1
YNR019W ARE2 sterol metabolism ->
alcohol metabolism, lipid metabolism sterol O-acyltransferase activity ->
sterol O-acyltransferase activity endoplasmic reticulum ->
cytoplasm
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YOL122C SMF1 manganese ion transport ->
transport manganese ion transporter activity ->
manganese ion transporter activity plasma membrane, vacuole (sensu Fungi) ->
plasma membrane, cytoplasm
YOR187W TUF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity mitochondrial matrix, mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex HAP4, REB1
|YMR018W| NO SYMBOL PHD1
Main: biosynthesis (0.40) manganese ion transporter activity (0.20) cytoplasm (0.80) SWI4 (0.17)
Score: 0.20 0.00 0.70 0.000
P-value: 4.085E+00 (transport) 9.525E-01 (transporter activity) 3.307E-01 (mitochondrial matrix) 7.006E-01 (ARG81)

m_allantoin_and_allantoate_transporters_orfnum2SD_n18(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YGR234W) OR SimExpr(other) : 5 2

m_pentose-phosphate_pathway_orfnum2SD_n5(1) AND m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n7(1) => SimExpr(YGR234W) OR SimExpr(other) : 6 2

EXPR: (0.202) m_pentose-phosphate_pathway_orfnum2SD_n5 (P < 0.000) m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n7 (P < 0.004)

ORF SYMBOL P F C TF
YHR121W NO SYMBOL SIP4
YGR234W YHB1 response to stress ->
response to stress ACE2, CAD1, CIN5, DAL82, HAP2, HAP3, SWI5, YAP1
YAL039C CYC3 cytochrome c-heme linkage ->
protein metabolism holocytochrome c synthase activity ->
holocytochrome c synthase activity mitochondrial intermembrane space ->
cytoplasm
|YGR146C| NO SYMBOL HSF1
YMR194W RPL36A protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
|YOL122C| SMF1 manganese ion transport ->
transport manganese ion transporter activity ->
manganese ion transporter activity plasma membrane, vacuole (sensu Fungi) ->
plasma membrane, cytoplasm
YLR412W NO SYMBOL
YMR230W RPS10B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, RAP1
Main: protein metabolism (0.60) structural constituent of ribosome (0.50) cytoplasm (1.00) RAP1 FHL1 (0.40)
Score: 0.30 0.17 1.00 0.100
P-value: 1.895E+00 (protein biosynthesis) 3.394E-01 (structural constituent of ribosome) 4.416E-01 (cytosolic ribosome (sensu Eukarya)) 5.705E-01 (FHL1)

m_LFTE17(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YIL133C) OR SimExpr(other) : 6 2

EXPR: (0.191) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.000) m_LFTE17 (P < 0.000) m_cell_death_orfnum2SD_n16 (P < 0.000)

ORF SYMBOL P F C TF
YKR042W UTH1 mitochondrion organization and biogenesis ->
cell organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
|YNL241C| ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
|YML111W| BUL2 protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism PDR1, SMP1, SWI5, YAP5
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
amine metabolism, alcohol metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity mitochondrion ->
cytoplasm
YDR276C PMP3 cation transport ->
transport plasma membrane ->
plasma membrane GAT1
YDR381W YRA1 mRNA-nucleus export ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding transcription export complex ->
nucleus ARO80
YOR096W RPS7A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, FKH2, RAP1
YIL133C RPL16A protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, PUT3, RAP1, RGM1, SFP1, SMP1, YAP5
Main: protein metabolism (0.38) RNA binding (0.40) cytoplasm (0.71) FKH2 (0.43)
Score: 0.21 0.20 0.48 0.333
P-value: 1.230E-01 (water-soluble vitamin metabolism) 6.789E-01 (structural constituent of ribosome) 5.398E-01 (cytosolic ribosome (sensu Eukarya)) 3.518E-02 (FKH2)

m_phosphate_transport_orfnum2SD_n18(1) AND mRRPE(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YIL133C) OR SimExpr(other) : 5 1

EXPR: (0.160) mRRPE (P < 0.000) m_phosphate_transport_orfnum2SD_n18 (P < 0.000) m_amino-acid_transport_orfnum2SD_n18 (P < 0.000)

ORF SYMBOL P F C TF
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic large ribosomal subunit (sensu Eukarya) GRF10(Pho2)
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YDR341C NO SYMBOL GCN4, ZMS1
|YFR031C| SMC2 mitotic chromosome condensation, mitotic chromosome segregation ->
cell cycle DNA secondary structure binding, AT DNA binding, double-stranded DNA binding, ATPase activity ->
DNA secondary structure binding, AT DNA binding, double-stranded DNA binding, ATPase activity nuclear condensin complex ->
nuclear condensin complex INO2, MET4
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
YIL133C RPL16A protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic large ribosomal subunit (sensu Eukarya) FHL1, GAT3, PDR1, PUT3, RAP1, RGM1, SFP1, SMP1, YAP5
Main: biosynthesis (0.60) structural constituent of ribosome (0.40) cytosolic large ribosomal subunit (sensu Eukarya) (0.67) PUT3 (0.20)
Score: 0.40 0.10 0.33 0.000
P-value: 1.412E+00 (biosynthesis) 3.452E-01 (structural constituent of ribosome) 8.553E-02 (cytosolic large ribosomal subunit (sensu Eukarya)) 6.901E-01 (PUT3)

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) AND m_cell_death_orfnum2SD_n16(1) => SimExpr(YIL133C) OR SimExpr(other) : 7 3

EXPR: (0.215) m_glyoxylate_cycle_orfnum2SD_n8 (P < 0.000) m_metabolism_of_energy_reserves_orfnum2SD_n8 (P < 0.000) m_cell_death_orfnum2SD_n16 (P < 0.003)

ORF SYMBOL P F C TF
YKR042W UTH1 mitochondrion organization and biogenesis ->
cell organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
|YOL012C| HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging chromatin binding ->
chromatin binding chromatin assembly complex, nuclear chromatin ->
nucleus, chromosome SWI4
|YMR196W| NO SYMBOL
|YGR088W| CTT1 response to stress ->
response to stress catalase activity ->
catalase activity cytoplasm ->
cytoplasm
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
YAR035W YAT1 carnitine metabolism, alcohol metabolism ->
amine metabolism, alcohol metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity mitochondrion ->
cytoplasm
YDR276C PMP3 cation transport ->
transport plasma membrane ->
plasma membrane GAT1
YOR096W RPS7A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, FKH2, RAP1
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
YIL133C RPL16A protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, PUT3, RAP1, RGM1, SFP1, SMP1, YAP5
Main: cell organization and biogenesis (0.33) structural constituent of ribosome (0.29) cytoplasm (0.67) SWI4 ACE2 FKH2 RAP1 SKN7 FHL1 (0.29)
Score: 0.11 0.05 0.44 0.190
P-value: 3.609E+00 (protein biosynthesis) 1.007E+00 (structural constituent of ribosome) 9.663E-01 (cytosolic ribosome (sensu Eukarya)) 1.799E-01 (ACE2)

m_RPE8(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YIL133C) OR SimExpr(other) : 9 4

EXPR: (0.205) m_phosphate_transport_orfnum2SD_n18 (P < 0.000) m_RPE8 (P < 0.029)

m_RPE57(1) AND m_LFTE17(1) => SimExpr(YIL133C) OR SimExpr(other) : 6 2

m_RPE57(1) AND m_RPE8(1) => SimExpr(YIL133C) : 5

m_lysosomal_and_vacuolar_degradation_orfnum2SD_n8(1) AND m_fermentation_orfnum2SD_n18(1) => SimExpr(YMR085W) OR SimExpr(other) : 5 1

EXPR: (0.200) m_lysosomal_and_vacuolar_degradation_orfnum2SD_n8 (P < 0.001) m_fermentation_orfnum2SD_n18 (P < 0.000)

ORF SYMBOL P F C TF
|YKR036C| CAF4 regulation of transcription\, DNA-dependent ->
regulation of transcription\, DNA-dependent protein binding ->
protein binding CCR4-NOT complex ->
CCR4-NOT complex IXR1
YFL061W NO SYMBOL
YJL213W NO SYMBOL
YOL153C NO SYMBOL
YNL335W NO SYMBOL MAL13, SWI5
YMR085W NO SYMBOL DAL81
Main: regulation of transcription\, DNA-dependent (1.00) protein binding (1.00) CCR4-NOT complex (1.00) MAL13 (0.33)
Score: 0.00 0.00 0.00 0.000
P-value: 0.000E+00 0.000E+00 0.000E+00 2.708E-01 (MAL13)

SFF(1) AND ECB(1) AND m_g-proteins_orfnum2SD_n11(1) AND SCB(1) => SimExpr(YNL053W) OR SimExpr(other) : 5 2

EXPR: (0.217) m_g-proteins_orfnum2SD_n11 (P < 0.000) ECB (P < 0.005) SFF (P < 0.000) SCB (P < 0.000)

ORF SYMBOL P F C TF
|YPL255W| BBP1 microtubule nucleation ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton spindle pole body ->
cytoplasm STB1, SWI4
YNL053W MSG5 adaptation to pheromone during conjugation with cellular fusion ->
conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus prenylated protein tyrosine phosphatase activity ->
prenylated protein tyrosine phosphatase activity DIG1, FKH1, MCM1
YGR143W SKN1 cell wall organization and biogenesis, beta-1\,6 glucan biosynthesis ->
cell organization and biogenesis, biosynthesis, carbohydrate metabolism glucosidase activity ->
glucosidase activity integral to membrane ->
integral to membrane HSF1, MCM1, NDD1, RAP1, SMP1
YMR102C NO SYMBOL
YJL133W MRS3 transport, RNA splicing ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism carrier activity ->
carrier activity mitochondrion ->
cytoplasm CBF1, RAP1
YMR010W NO SYMBOL
|YLR272C| YCS4 mitotic chromosome condensation ->
cell proliferation, cell cycle nuclear condensin complex ->
chromosome, nucleus
Main: cell organization and biogenesis (0.40) structural constituent of cytoskeleton (0.25) cytoplasm (0.50) RAP1 MCM1 (0.50)
Score: 0.10 0.00 0.17 0.333
P-value: 3.913E+00 (cell growth and/or maintenance) 1.611E+00 (hydrolase activity) 4.869E+00 (cytoplasm) 2.139E-01 (MCM1)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND ECB(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YNL053W) OR SimExpr(other) : 5 2

EXPR: (0.217) ECB (P < 0.002) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.001) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.000)

ORF SYMBOL P F C TF
YGR161C RTS3 CIN5, GAT1
YNL053W MSG5 adaptation to pheromone during conjugation with cellular fusion ->
adaptation to pheromone during conjugation with cellular fusion prenylated protein tyrosine phosphatase activity ->
prenylated protein tyrosine phosphatase activity DIG1, FKH1, MCM1
YNL164C IBD2 mitotic spindle checkpoint ->
mitotic spindle checkpoint nucleus ->
nucleus
YDR293C SSD1 cell wall organization and biogenesis ->
cell wall organization and biogenesis RNA binding ->
RNA binding cytoplasm ->
cytoplasm
YJL051W NO SYMBOL FKH2, MCM1, NDD1, PHO4
|YOL155C| NO SYMBOL MAC1, MET4, PUT3, YAP6
|YDR541C| NO SYMBOL DOT6, INO2, RCS1, USV1
Main: mitotic spindle checkpoint (0.33) RNA binding (0.50) cytoplasm (0.50) MCM1 (0.40)
Score: 0.00 0.00 0.00 0.100
P-value: 4.769E+00 (cell growth and/or maintenance) 2.000E+00 4.000E+00 (intracellular) 3.423E-01 (MCM1)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_RRSE3(1) AND m_g-proteins_orfnum2SD_n12(1) AND PAC(1) => SimExpr(YGL078C) OR SimExpr(other) : 9 4

SFF(1) AND m_organization_of_cell_wall_orfnum2SD_n6(1) AND CSRE(1) => SimExpr(YNR019W) OR SimExpr(other) : 6 2

EXPR: (0.214) SFF (P < 0.001) CSRE (P < 0.001) m_organization_of_cell_wall_orfnum2SD_n6 (P < 0.002)

ORF SYMBOL P F C TF
YOR003W YSP3 protein catabolism ->
catabolism, protein metabolism peptidase activity ->
peptidase activity
|YKL077W| NO SYMBOL CHA4, GCR1, HAP3, HIR1, IXR1, REB1, STP1
YNL069C RPL16B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YNR019W ARE2 sterol metabolism ->
alcohol metabolism, lipid metabolism sterol O-acyltransferase activity ->
sterol O-acyltransferase activity endoplasmic reticulum ->
cytoplasm
YKR003W OSH6 steroid biosynthesis ->
biosynthesis, lipid metabolism oxysterol binding ->
oxysterol binding
YMR148W NO SYMBOL
|YDR134C| NO SYMBOL ASH1, NRG1, SOK2, SWI4
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
Main: biosynthesis (0.40) structural constituent of cell wall (0.20) cytoplasm (0.67) SWI4 (0.50)
Score: 0.30 0.00 0.33 0.167
P-value: 3.367E-02 (steroid metabolism) 1.026E+00 (structural molecule activity) 4.937E+00 (cytoplasm) 8.645E-01 (SWI4)

m_deoxyribonucleotide_metabolism_orfnum2SD_n10(1) AND m_ion_transporters_orfnum2SD_n3(1) => SimExpr(YNR019W) OR SimExpr(other) : 11 5

EXPR: (0.236) m_deoxyribonucleotide_metabolism_orfnum2SD_n10 (P < 0.003) m_ion_transporters_orfnum2SD_n3 (P < 0.004)

m_PNDE6(1) AND RPN4(1) => SimExpr(YHR027C) OR SimExpr(other) : 5 2

EXPR: (0.235) RPN4 (P < 0.057) m_PNDE6 (P < 0.001)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND PAC(1) => SimExpr(YDR496C) OR SimExpr(other) : 6 2

EXPR: (0.207) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) PAC (P < 0.005) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.000)

ORF SYMBOL P F C TF
YAL059W ECM1 cell wall organization and biogenesis ->
cell organization and biogenesis MOT3
YDR496C PUF6 RFX1
YJL010C NO SYMBOL
YHR169W DBP8 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA helicase activity, ATP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides nucleolus ->
nucleus
|YNL308C| KRI1 ribosome biogenesis ->
cell organization and biogenesis nucleolus ->
nucleus
YNR053C NOG2 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism GTPase activity ->
GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides nucleus, nucleolus, nucleoplasm ->
nucleus, nucleoplasm ABF1, AZF1
YNL112W DBP2 RNA helicase activity ->
RNA helicase activity bud neck ->
site of polarized growth (sensu Fungi)
|YDR076W| RAD55 meiotic DNA recombinase assembly, DNA recombinase assembly, double-strand break repair via synthesis-dependent strand annealing, double-strand break repair via break-induced replication, double-strand break repair via single-strand annealing ->
mating-type determination, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein binding ->
protein binding nucleus ->
nucleus DAL81
Main: cell organization and biogenesis (0.60) RNA helicase activity (0.50) nucleus (0.80) ABF1 (0.25)
Score: 0.60 0.33 0.60 0.000
P-value: 5.481E-01 (ribosome biogenesis) 4.290E-02 (RNA helicase activity) 1.990E-02 (nucleolus) 4.780E-01 (AZF1)

m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND m_RRSE3(1) AND PAC(1) => SimExpr(YDR496C) OR SimExpr(other) : 6 1

EXPR: (0.191) m_RRSE3 (P < 0.000) PAC (P < 0.001) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.000)

ORF SYMBOL P F C TF
YDR496C PUF6 RFX1
YDR184C ATC1 response to stress, polar budding ->
response to stress, polar budding nucleus ->
nucleus ARO80, GLN3, SIP4, SKO1
YJL010C NO SYMBOL
|YNL175C| NOP13 RNA binding ->
RNA binding nucleolus, nucleoplasm ->
nucleus INO2, INO4
YHR169W DBP8 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
YNR053C NOG2 mRNA splicing ->
RNA processing GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleus, nucleolus, nucleoplasm ->
nucleus, nucleoplasm ABF1, AZF1
YNL112W DBP2 RNA helicase activity ->
RNA binding bud neck ->
site of polarized growth (sensu Fungi)
Main: RNA processing (0.67) RNA binding (0.75) nucleus (0.80) ABF1 (0.25)
Score: 0.33 0.67 0.60 0.000
P-value: 6.493E-01 (RNA processing) 3.239E-02 (RNA helicase activity) 1.495E-02 (nucleolus) 6.053E-01 (SKO1)

m_RRSE3(1) AND m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND PAC(1) => SimExpr(YDR496C) OR SimExpr(other) : 5 1

EXPR: (0.203) m_RRSE3 (P < 0.000) PAC (P < 0.010) m_biogenesis_of_chromosome_structure_orfnum2SD_n9 (P < 0.000)

ORF SYMBOL P F C TF
YHR146W CRP1 DNA binding ->
DNA binding nucleus ->
nucleus IXR1
YNL141W AAH1 adenine catabolism ->
aromatic compound metabolism, catabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism adenine deaminase activity ->
adenine deaminase activity YFL044C
YDR496C PUF6 RFX1
|YGR191W| HIP1 manganese ion transport, histidine transport ->
transport, organic acid transport histidine transporter activity ->
histidine transporter activity plasma membrane ->
plasma membrane GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleus ->
nucleus STB1
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
snoRNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.75) DNA binding (0.25) nucleus (0.75) ABF1 (0.17)
Score: 0.50 0.00 0.50 0.000
P-value: 2.201E-01 (rRNA processing) 1.103E+00 (nucleic acid binding) 1.786E+00 (nucleus) 8.998E-01 (STB1)

m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND m_g-proteins_orfnum2SD_n12(1) AND PAC(1) AND mRRPE(1) => SimExpr(YDR496C) OR SimExpr(other) : 5 1

EXPR: (0.191) mRRPE (P < 0.000) m_g-proteins_orfnum2SD_n12 (P < 0.000) PAC (P < 0.005) m_biogenesis_of_chromosome_structure_orfnum2SD_n9 (P < 0.000)

ORF SYMBOL P F C TF
YDR496C PUF6 RFX1
YPR144C NOC4 ribosome biogenesis ->
cytoplasm organization and biogenesis nucleus ->
nucleus HIR1
YJL069C UTP18 ABF1
YOR359W VTS1 protein-vacuolar targeting ->
cytoplasm organization and biogenesis, intracellular transport, protein metabolism, protein transport intracellular transporter activity ->
intracellular transporter activity cytosol ->
cytoplasm RAP1
YLR222C UTP13 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
snoRNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
|YJL148W| RPA34 transcription from Pol I promoter ->
transcription DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex, nucleus, nucleolus ->
nucleus AZF1, CHA4, CUP9, DAL81, DIG1, FZF1, GCR1, GCR2, GLN3, HAL9, HAP2, HAP3, HMS1, LEU3, MAC1, MBP1, MET31, MOT3, NDD1, PDR1, PHD1, REB1, RLM1, RME1, ROX1, RPH1, RTS2, SKN7, SWI5, YAP6, ZAP1
Main: cytoplasm organization and biogenesis (0.75) intracellular transporter activity (0.33) nucleus (0.75) ABF1 (0.33)
Score: 0.67 0.00 0.50 0.067
P-value: 2.525E-01 (transcription from Pol I promoter) 2.000E+00 1.380E-01 (nucleolus) 1.000E+00

m_nitrogen_and_sulphur_metabolism_orfnum2SD_n16(1) AND m_fermentation_orfnum2SD_n18(1) => SimExpr(YDR214W) OR SimExpr(other) : 5 2

EXPR: (0.222) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n16 (P < 0.003) m_fermentation_orfnum2SD_n18 (P < 0.002)

ORF SYMBOL P F C TF
|YKL210W| UBA1 ubiquitin cycle ->
catabolism, protein metabolism ubiquitin activating enzyme activity ->
ubiquitin activating enzyme activity nucleus, cytoplasm ->
nucleus, cytoplasm SKO1
YOR007C SGT2
YPL223C GRE1 response to dessication, response to stress ->
response to abiotic stimulus, response to stress cytoplasm ->
cytoplasm
|YJL082W| IML2
YGR157W CHO2 phosphatidylcholine biosynthesis ->
biosynthesis, lipid metabolism phosphatidylethanolamine N-methyltransferase activity ->
phosphatidylethanolamine N-methyltransferase activity endoplasmic reticulum ->
cytoplasm DAL81, INO2, INO4, MET4, SFL1
YMR088C NO SYMBOL
YDR214W AHA1 protein folding, response to stress ->
protein metabolism, response to stress chaperone activator activity ->
chaperone activator activity cytoplasm ->
cytoplasm HSF1
Main: response to stress (0.50) ubiquitin activating enzyme activity (0.33) cytoplasm (1.00) SFL1 (0.33)
Score: 0.33 0.00 1.00 0.000
P-value: 3.114E-01 (response to stress) 2.849E+00 (enzyme activity) 3.294E+00 (cytoplasm) 4.708E-01 (SKO1)

m_peroxisomal_transport_orfnum2SD_n22(1) AND m_other_transcription_activities_orfnum2SD_n5(1) => SimExpr(YLR241W) OR SimExpr(other) : 5 2

EXPR: (0.225) m_other_transcription_activities_orfnum2SD_n5 (P < 0.028) m_peroxisomal_transport_orfnum2SD_n22 (P < 0.003)

ORF SYMBOL P F C TF
YOR155C ISN1
|YGR109C| CLB6 regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis ->
regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity MBP1, STB1, SWI4, SWI6
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
mitochondrion, respiratory chain complex III (sensu Eukarya) HAP4, MBP1
|YDR134C| NO SYMBOL ASH1, NRG1, SOK2, SWI4
YMR247C NO SYMBOL HSF1
YHR087W NO SYMBOL CRZ1, GAL4, MSN4, PDR1, SMP1, YAP5
YLR241W NO SYMBOL
Main: premeiotic DNA synthesis (0.50) ubiquinol-cytochrome c reductase activity (0.50) mitochondrion (1.00) SWI4 MBP1 (0.40)
Score: 0.00 0.00 0.00 0.200
P-value: 3.979E+00 (metabolism) 2.849E+00 (enzyme activity) 0.000E+00 2.761E-01 (MBP1)

m_amino-acid_transport_orfnum2SD_n3(1) AND m_nitrogen_and_sulphur_metabolism_orfnum2SD_n16(1) => SimExpr(YGR184C) OR SimExpr(other) : 5 1

EXPR: (0.226) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n16 (P < 0.003) m_amino-acid_transport_orfnum2SD_n3 (P < 0.002)

ORF SYMBOL P F C TF
YIL033C BCY1 response to stress, pseudohyphal growth, signal transduction, response to heat ->
response to stress, cell organization and biogenesis, signal transduction, response to abiotic stimulus cAMP-dependent protein kinase inhibitor activity ->
cAMP-dependent protein kinase inhibitor activity nucleus, cytoplasm ->
nucleus, cytoplasm
YNR074C NO SYMBOL GTS1
|YDR044W| HEM13 heme biosynthesis ->
pigment metabolism, coenzymes and prosthetic group biosynthesis, coenzymes and prosthetic group metabolism, biosynthesis, heterocycle metabolism coproporphyrinogen oxidase activity ->
coproporphyrinogen oxidase activity mitochondrial inner membrane ->
cytoplasm, inner membrane
YGR184C UBR1 protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity proteasome complex (sensu Eukarya) ->
cytoplasm, nucleus HMS1, REB1, RIM101
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YJL082W IML2
Main: catabolism (0.50) arginase activity (0.25) cytoplasm (1.00) REB1 (0.33)
Score: 0.17 0.00 1.00 0.000
P-value: 4.334E-01 (development) 2.077E+00 (enzyme activity) 9.744E-01 (cytosol) 2.030E-01 (HMS1)

ABF1(1) AND m_amino-acid_transport_orfnum2SD_n13(1) => SimExpr(YNL138W) OR SimExpr(other) : 5 2

m_RPE8(1) AND m_other_intracellular-transport_activities_orfnum2SD_n6(1) => SimExpr(YDR086C) OR SimExpr(other) : 5 2

m_RPE8(1) AND CSRE(1) => SimExpr(YDR086C) OR SimExpr(other) : 12 3

m_MERE4(1) AND m_RPE8(1) => SimExpr(YDR086C) : 7

ALPHA1(1) AND m_organization_of_chromosome_structure_orfnum2SD_n12(1) AND CSRE(1) => SimExpr(YDR086C) : 5

EXPR: (0.149) m_organization_of_chromosome_structure_orfnum2SD_n12 (P < 0.000) CSRE (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YAR020C PAU7
YGR254W ENO1 gluconeogenesis, glycolysis ->
monosaccharide biosynthesis, monosaccharide catabolism, main pathways of carbohydrate metabolism, hexose metabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YDR134C NO SYMBOL ASH1, NRG1, SOK2, SWI4
YKL141W SDH3 oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, main pathways of carbohydrate metabolism, phosphorylation succinate dehydrogenase activity ->
succinate dehydrogenase activity respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
YDR086C SSS1 cotranslational membrane targeting ->
organelle organization and biogenesis, intracellular protein transport, secretory pathway, protein metabolism protein transporter activity ->
protein transporter activity translocon ->
cytoplasm HIR1, IXR1, MIG1, RFX1, SIP4
Main: main pathways of carbohydrate metabolism (0.67) phosphopyruvate hydratase activity (0.33) cytoplasm (1.00) SWI4 (0.33)
Score: 0.33 0.00 1.00 0.000
P-value: 4.220E-02 (main pathways of carbohydrate metabolism) 2.509E+00 (enzyme activity) 3.185E+00 (cytoplasm) 6.789E-01 (ASH1)

SFF(1) AND PAC(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YPR137W) OR SimExpr(other) : 5 2

EXPR: (0.219) SFF (P < 0.000) PAC (P < 0.017) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.000)

ORF SYMBOL P F C TF
YDR101C ARX1 ribosomal large subunit biogenesis ->
ribosome biogenesis nucleoplasm, cytoplasm ->
nucleus, cytoplasm IXR1, RFX1
|YNL299W| TRF5 sister chromatid cohesion ->
chromosome condensation DNA-directed DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups nucleus ->
nucleus
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YLR222C UTP13 processing of 20S pre-rRNA ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YPR137W RRP9 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, HIR1, RCS1
YKL120W OAC1 oxaloacetate transport, sulfate transport ->
organic anion transport, inorganic anion transport, carboxylic acid transport oxaloacetate carrier activity, sulfate porter activity ->
electrochemical potential-driven transporter activity, anion transporter activity, organic cation transporter activity, carboxylic acid transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane LEU3, MTH1
Main: ribosome biogenesis (0.67) RNA binding (0.60) nucleus (0.83) ABF1 (0.33)
Score: 0.40 0.30 0.73 0.067
P-value: 1.796E-03 (ribosome biogenesis) 6.072E-03 (snoRNA binding) 1.350E-02 (small nucleolar ribonucleoprotein complex) 6.647E-01 (THI2)

SFF'(1) AND PAC(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YPR137W) OR SimExpr(other) : 5 2

EXPR: (0.219) SFF' (P < 0.000) PAC (P < 0.017) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.000)

m_g-proteins_orfnum2SD_n11(1) AND PAC(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YPR137W) : 5

EXPR: (0.161) m_g-proteins_orfnum2SD_n11 (P < 0.000) PAC (P < 0.001) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.000)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_pentose-phosphate_pathway_orfnum2SD_n21(1) => SimExpr(YOR264W) OR SimExpr(other) : 6 2

EXPR: (0.236) m_pentose-phosphate_pathway_orfnum2SD_n21 (P < 0.044) m_other_signal-transduction_activities_orfnum2SD_n8 (P < 0.018)

ORF SYMBOL P F C TF
YNL241C ZWF1 pentose-phosphate shunt ->
pentose-phosphate shunt glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
|YMR180C| CTL1 RNA processing ->
RNA processing polynucleotide 5'-phosphatase activity ->
polynucleotide 5'-phosphatase activity nucleus, cytoplasm ->
nucleus, cytoplasm SWI6
|YKR092C| SRP40 nucleocytoplasmic transport ->
nucleocytoplasmic transport chaperone activity ->
chaperone activity nucleolus ->
nucleus CUP9, MET4, RAP1
YLR354C TAL1 pentose-phosphate shunt ->
pentose-phosphate shunt transaldolase activity ->
transaldolase activity cytoplasm ->
cytoplasm MBP1
YKL167C MRP49 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex ABF1, IME4, IXR1
YGR035C NO SYMBOL CIN5, MET4, SMP1, YAP6
YOR264W DSE3 SWI5
YNL067W RPL9B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1
Main: pentose-phosphate shunt (0.33) structural constituent of ribosome (0.33) cytoplasm (0.83) IME4 RAP1 MET4 SWI5 MBP1 (0.25)
Score: 0.13 0.07 0.73 0.179
P-value: 4.432E-03 (pentose-phosphate shunt) 4.243E-01 (structural constituent of ribosome) 2.748E-01 (large ribosomal subunit) 5.554E-02 (IME4)

SFF(1) AND PAC(1) AND m_rRSE10(1) => SimExpr(YGR145W) OR SimExpr(other) : 7 3

EXPR: (0.223) SFF (P < 0.000) m_rRSE10 (P < 0.000) PAC (P < 0.041)

ORF SYMBOL P F C TF
YDR101C ARX1 ribosomal large subunit biogenesis ->
ribosome biogenesis and assembly nucleoplasm, cytoplasm ->
nucleus, cytoplasm IXR1, RFX1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YKL078W DHR2 ribosome biogenesis ->
ribosome biogenesis and assembly RNA helicase activity ->
RNA binding nucleolus ->
nucleus ABF1
YGR145W ENP2
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus MATa1, RCS1, RTG3, SWI5
|YOR381W| FRE3 iron-siderochrome transport, iron ion homeostasis ->
iron-siderochrome transport, cation homeostasis ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions plasma membrane, integral to membrane ->
plasma membrane, integral to membrane CIN5, PDR1, YAP6
|YLR249W| YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent RNA binding ->
RNA binding nucleolus ->
nucleus
YOL141W PPM2 C-terminal protein carboxyl methyltransferase activity ->
transferase activity\, transferring one-carbon groups ARG81, SRD1
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
Main: ribosome biogenesis and assembly (0.62) RNA binding (0.50) nucleus (0.62) SWI5 (0.25)
Score: 0.39 0.21 0.46 0.036
P-value: 5.589E-04 (ribosome biogenesis) 2.929E-03 (RNA helicase activity) 3.785E-03 (nucleolus) 3.378E-01 (SWI5)

SFF'(1) AND PAC(1) AND m_rRSE10(1) => SimExpr(YGR145W) OR SimExpr(other) : 9 3

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND SFF(1) AND PAC(1) => SimExpr(YGR145W) OR SimExpr(other) : 18 8

EXPR: (0.243) SFF (P < 0.000) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) PAC (P < 0.091)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND SFF(1) AND PAC(1) AND mRRPE(1) => SimExpr(YGR145W) OR SimExpr(other) : 10 3

EXPR: (0.223) SFF (P < 0.000) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.022)

ORF SYMBOL P F C TF
YJL109C UTP10 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YGL078C DBP3 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
YDR496C PUF6 RFX1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
membrane lipid biosynthesis, macromolecule biosynthesis, phospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism, protein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YGR145W ENP2
|YGL016W| KAP122 protein-nucleus import, response to drug ->
response to chemical substance, intracellular transport, protein metabolism, protein transport protein carrier activity ->
protein carrier activity cytoplasm, nuclear pore ->
cytoplasm, nucleus, integral to membrane, endomembrane system MSN2
YOL022C NO SYMBOL MAC1, MOT3, RTS2
|YLR249W| YEF3 translational elongation ->
macromolecule biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YDR449C UTP6 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YHR169W DBP8 35S primary transcript processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
YNR053C NOG2 mRNA splicing ->
RNA metabolism GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleus, nucleolus, nucleoplasm ->
nucleus, nucleoplasm ABF1, AZF1
Main: RNA metabolism (0.62) RNA binding (0.50) nucleus (0.75) ABF1 HIR1 (0.22)
Score: 0.46 0.29 0.71 0.056
P-value: 1.075E-02 (rRNA processing) 5.180E-02 (ATP dependent RNA helicase activity) 1.156E-03 (nucleolus) 5.980E-01 (HIR1)

SFF(1) AND PAC(1) AND mRRPE(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YGR145W) OR SimExpr(other) : 5 2

m_other_pheromone_response_activities_orfnum2SD_n12(1) AND m_other_morphogenetic_activities_orfnum2SD_n7(1) AND mRRPE(1) => SimExpr(YGR145W) OR SimExpr(other) : 5 2

EXPR: (0.220) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) mRRPE (P < 0.006) m_other_pheromone_response_activities_orfnum2SD_n12 (P < 0.000)

ORF SYMBOL P F C TF
YGR145W ENP2
|YGL211W| NO SYMBOL
YML111W BUL2 protein polyubiquitination, protein monoubiquitination ->
macromolecule catabolism, protein modification, protein metabolism PDR1, SMP1, SWI5, YAP5
YMR229C RRP5 rRNA processing, processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription RNA binding, snoRNA binding ->
RNA binding, snoRNA binding nucleolus, nucleolus organizer complex ->
nucleus FHL1, RAP1
YLR278C NO SYMBOL INO4, MSN1
YGR162W TIF4631 translational initiation ->
macromolecule biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex HSF1
|YOL139C| CDC33 translational initiation, regulation of cell cycle ->
macromolecule biosynthesis, cell cycle, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome, nucleus, cytoplasm ->
cytoplasm, nucleus, ribonucleoprotein complex ARG81
Main: protein metabolism (0.75) translation initiation factor activity (0.67) cytoplasm (0.67) PDR1 (0.20)
Score: 0.50 0.33 0.67 0.000
P-value: 2.830E-02 (translational initiation) 2.247E-02 (translation initiation factor activity) 8.247E-01 (ribosome) 2.973E-01 (MSN1)

ALPHA1(1) AND MCB(1) => SimExpr(YNL082W) OR SimExpr(other) : 22 10

MCB(1) AND m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) => SimExpr(YNL082W) OR SimExpr(other) : 6 1

ALPHA1(1) AND MCB(1) AND m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) => SimExpr(YNL082W) : 5

SFF(1) AND CSRE(1) AND m_intracellular_communication_orfnum2SD_n4(1) => SimExpr(YLR413W) OR SimExpr(other) : 5 2

EXPR: (0.228) SFF (P < 0.000) CSRE (P < 0.000) m_intracellular_communication_orfnum2SD_n4 (P < 0.000)

ORF SYMBOL P F C TF
YLR413W NO SYMBOL AZF1, CIN5, NRG1, RLM1, SOK2, YAP6
YGR090W UTP22 ZMS1
YOR382W FIT2 siderochrome transport ->
siderochrome transport cell wall (sensu Fungi) ->
cell wall (sensu Fungi)
|YLR205C| HMX1 iron ion homeostasis ->
iron ion homeostasis peroxidase activity, heme binding, heme oxygenase (decyclizing) activity ->
peroxidase activity, heme binding, heme oxygenase (decyclizing) activity membrane ->
membrane MAL13, PHO4, SKN7
YML042W CAT2 carnitine metabolism ->
carnitine metabolism carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity peroxisomal matrix, mitochondrion, peroxisome ->
peroxisomal matrix, mitochondrion, peroxisome MAL13
|YMR291W| NO SYMBOL RAP1
YNL251C NRD1 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleus ->
nucleus ABF1, MAC1
Main: iron ion homeostasis (0.25) RNA binding (0.33) membrane (0.25) MAL13 (0.33)
Score: 0.00 0.00 0.00 0.067
P-value: 5.723E+00 (cell growth and/or maintenance) 2.769E+00 (binding) 4.000E+00 (intracellular) 3.416E-02 (MAL13)

ALPHA1'(1) AND m_amino-acid_transport_orfnum2SD_n14(1) AND m_rRSE10(1) => SimExpr(YOR381W) OR SimExpr(other) : 5 2

ALPHA1(1) AND MCB(1) => SimExpr(YDR097C) OR SimExpr(other) : 23 9

MCB(1) AND m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) => SimExpr(YDR097C) : 7

m_phosphate_transport_orfnum2SD_n18(1) AND m_cell_death_orfnum2SD_n16(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn(1) => SimExpr(YLR300W) OR SimExpr(other) : 5 2

EXPR: (0.224) m_phosphate_transport_orfnum2SD_n18 (P < 0.005) m_cell_death_orfnum2SD_n16 (P < 0.008) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn (P < 0.007)

ORF SYMBOL P F C TF
YLR300W EXG1 cell wall organization and biogenesis, glucan metabolism ->
cell organization and biogenesis, carbohydrate metabolism glucan 1\,3-beta-glucosidase activity ->
glucan 1\,3-beta-glucosidase activity cell wall (sensu Fungi) ->
cell wall (sensu Fungi) ASH1, FKH2, MBP1, MET4, NDD1, RAP1, RLM1, SMP1, SWI4, SWI6
YPL020C ULP1 G2/M transition of mitotic cell cycle, protein desumoylation ->
cell proliferation, protein metabolism cysteine-type peptidase activity, SUMO-specific protease activity ->
cysteine-type peptidase activity, SUMO-specific protease activity nuclear membrane, nuclear pore ->
nuclear membrane, nuclear pore ADR1
|YMR196W| NO SYMBOL
|YOR382W| FIT2 siderochrome transport ->
transport cell wall (sensu Fungi) ->
cell wall (sensu Fungi)
YML058W SML1 response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis enzyme inhibitor activity ->
enzyme inhibitor activity NDD1, RFX1, SWI6
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: cell organization and biogenesis (0.50) cysteine-type peptidase activity (0.25) cell wall (sensu Fungi) (0.50) NDD1 (0.60)
Score: 0.27 0.00 0.17 0.400
P-value: 4.241E-01 (carbohydrate metabolism) 5.394E-01 (hydrolase activity) 5.779E-02 (cell wall (sensu Fungi)) 1.614E-02 (NDD1)

m_RRSE3(1) AND PAC(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YMR229C) OR SimExpr(other) : 19 5

EXPR: (0.206) mRRPE (P < 0.000) m_RRSE3 (P < 0.000) PAC (P < 0.000) ALPHA1' (P < 0.000)

m_RRSE3(1) AND PAC(1) AND SWI5(1) AND ALPHA1'(1) => SimExpr(YMR229C) OR SimExpr(other) : 5 2

EXPR: (0.203) SWI5 (P < 0.000) m_RRSE3 (P < 0.001) PAC (P < 0.012) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
YPR010C RPA135 transcription from Pol I promoter ->
transcription DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
|YGR251W| NO SYMBOL MSN4, PHD1, SKN7
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cytoplasm organization and biogenesis, cell cycle nucleus ->
nucleus
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription nucleus ->
nucleus STB1
YMR229C RRP5 rRNA processing, processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription RNA binding, snoRNA binding ->
RNA binding, snoRNA binding nucleolus, nucleolus organizer complex ->
nucleus FHL1, RAP1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription RNA binding ->
RNA binding nucleolus ->
nucleus
Main: cytoplasm organization and biogenesis (0.80) RNA binding (0.67) nucleus (1.00) GCR2 (0.20)
Score: 0.90 0.33 1.00 0.000
P-value: 8.935E-04 (transcription from Pol I promoter) 5.131E-01 (RNA binding) 1.281E-02 (nucleolus) 6.204E-01 (THI2)

m_other_transport_facilitators_orfnum2SD_n10(1) AND m_phosphate_transport_orfnum2SD_n5(1) => SimExpr(YPR067W) OR SimExpr(other) : 7 3

EXPR: (0.219) m_phosphate_transport_orfnum2SD_n5 (P < 0.001) m_other_transport_facilitators_orfnum2SD_n10 (P < 0.000)

ORF SYMBOL P F C TF
YPR067W ISA2 iron ion transport ->
transport mitochondrial intermembrane space ->
cytoplasm REB1
|YOR348C| PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid permease activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YJL145W SFH5 phospholipid transport ->
transport phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity DIG1, HAP3, NRG1, RCS1, RFX1
YIL049W DFG10 pseudohyphal growth ->
cell organization and biogenesis
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YGR194C XKS1 xylulose catabolism ->
alcohol metabolism, carbohydrate catabolism, catabolism, carbohydrate metabolism xylulokinase activity ->
xylulokinase activity HSF1
YGR086C PIL1 ASH1, SWI5
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
|YKL104C| GFA1 cell wall chitin biosynthesis ->
cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity ->
glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity REB1
|YOR019W| NO SYMBOL CIN5
Main: carbohydrate metabolism (0.38) amino acid permease activity (0.17) cytoplasm (0.75) CIN5 SWI5 REB1 (0.22)
Score: 0.32 0.00 0.50 0.083
P-value: 1.022E-01 (glutamine family amino acid metabolism) 1.648E+00 (transporter activity) 2.186E+00 (cytosol) 2.534E-01 (SWI5)

m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8(1) AND m_nitrogen_and_sulphur_metabolism_orfnum2SD_n22(1) => SimExpr(YMR015C) OR SimExpr(other) : 5 1

EXPR: (0.176) m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8 (P < 0.002) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n22 (P < 0.003)

ORF SYMBOL P F C TF
YMR015C ERG5 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-22 sterol desaturase activity ->
C-22 sterol desaturase activity endoplasmic reticulum ->
intracellular PHD1, RAP1, YAP5
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
intracellular ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways L-malate dehydrogenase activity ->
malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrial matrix ->
intracellular IME4, MTH1, RTG1, YJL206C
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
nucleotidyltransferase activity
|YHR195W| NVJ1 microautophagy ->
autophagy protein binding ->
protein binding nuclear membrane ->
intracellular, membrane ACE2, MBP1, NRG1, SMP1
YAL022C FUN26 nucleoside transport ->
transport nucleoside transporter activity ->
nucleoside transporter activity intracellular, membrane ->
intracellular, membrane ADR1, FHL1, FZF1, IME4, MAC1, MATa1, NRG1, PDR1, SFP1, SMP1, STB1, SWI5, YFL044C
Main: alcohol metabolism (0.50) oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.33) intracellular (1.00) IME4 (0.60)
Score: 0.33 0.07 1.00 0.500
P-value: 2.004E-02 (alcohol metabolism) 4.606E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 2.499E+00 (membrane) 4.472E-04 (IME4)

m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8(1) AND m_MERE4(1) => SimExpr(YMR015C) OR SimExpr(other) : 5 2

EXPR: (0.205) m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8 (P < 0.009) m_MERE4 (P < 0.003)

GCN4(1) AND m_other_energy_generation_activities_orfnum2SD_n22(1) => SimExpr(YGL059W) OR SimExpr(other) : 5 1

EXPR: (0.186) GCN4 (P < 0.003) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.000)

ORF SYMBOL P F C TF
YGL059W NO SYMBOL GCN4
YDR527W NO SYMBOL ABF1, SKN7
|YKR021W| NO SYMBOL
YLR290C NO SYMBOL MSS11
YKL211C TRP3 tryptophan biosynthesis ->
amino acid biosynthesis, biogenic amine biosynthesis, aromatic amino acid family metabolism, aromatic compound biosynthesis, indolalkylamine metabolism, indole derivative biosynthesis anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity CRZ1
YIL116W HIS5 histidine biosynthesis ->
amino acid biosynthesis, histidine family amino acid metabolism histidinol-phosphate aminotransferase activity ->
histidinol-phosphate aminotransferase activity cell ->
cell
Main: amino acid biosynthesis (1.00) anthranilate synthase activity (0.50) cell (1.00) ABF1 (0.25)
Score: 1.00 0.00 0.00 0.000
P-value: 1.312E-01 (amino acid biosynthesis) 2.725E+00 (enzyme activity) 0.000E+00 2.403E-01 (CRZ1)

m_phosphate_utilization_orfnum2SD_n9(1) AND m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND SCB(1) => SimExpr(YPR198W) OR SimExpr(other) : 5 2

EXPR: (0.235) m_phosphate_utilization_orfnum2SD_n9 (P < 0.008) SCB (P < 0.001) m_biogenesis_of_chromosome_structure_orfnum2SD_n9 (P < 0.001)

ORF SYMBOL P F C TF
|YNL141W| AAH1 adenine catabolism ->
aromatic compound metabolism, catabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism adenine deaminase activity ->
adenine deaminase activity YFL044C
YMR001C CDC5 DNA dependent DNA replication, protein amino acid phosphorylation ->
phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein serine/threonine kinase activity ->
protein serine/threonine kinase activity nucleus, spindle pole, bud neck ->
nucleus, spindle pole, bud neck NDD1, REB1, SWI6
YPR198W SGE1 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity integral to plasma membrane ->
integral to plasma membrane BAS1, DIG1, PHD1, SIP4, SMP1, STE12
|YOR338W| NO SYMBOL RAP1
YMR010W NO SYMBOL
YNR051C BRE5
YKR051W NO SYMBOL
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67) adenine deaminase activity (0.33) spindle pole (0.50) YFL044C (0.25)
Score: 0.33 0.00 0.00 0.000
P-value: 4.136E+00 (nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism) 1.611E+00 (hydrolase activity) 3.000E+00 (cell) 1.000E+00

SFF'(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) AND mRRPE(1) => SimExpr(YDR429C) OR SimExpr(other) : 10 4

EXPR: (0.229) SFF' (P < 0.000) mRRPE (P < 0.000) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YOL123W HRP1 mRNA cleavage, mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cleavage/polyadenylation specificity factor activity ->
mRNA binding mRNA cleavage factor complex, nucleus ->
nucleus
YOR004W NO SYMBOL FZF1, HIR1
YJR016C ILV3 branched chain family amino acid biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis dihydroxy-acid dehydratase activity ->
hydro-lyase activity mitochondrion ->
cytoplasm
YLR244C MAP1 proteolysis and peptidolysis ->
catabolism, protein metabolism methionyl aminopeptidase activity ->
aminopeptidase activity, exopeptidase activity, metallopeptidase activity cytosolic ribosome (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
|YDR374C| NO SYMBOL RME1
YDR429C TIF35 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity eukaryotic translation initiation factor 3 complex ->
cytoplasm RFX1
|YGL029W| CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YDR341C NO SYMBOL GCN4, ZMS1
YKL029C MAE1 pyruvate metabolism, amino acid metabolism ->
amine metabolism, organic acid metabolism, amino acid and derivative metabolism malate dehydrogenase (oxaloacetate decarboxylating) activity ->
malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrion ->
cytoplasm ABF1, CIN5
YLR175W CBF5 rRNA modification, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription pseudouridylate synthase activity ->
hydro-lyase activity small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex AZF1, HAL9
YML125C NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
YOR095C RKI1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity\, interconverting aldoses and ketoses FHL1, FKH2, RAP1
|YNL042W| BOP3 DAL82
|YOR066W| NO SYMBOL MBP1, MCM1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.38) hydro-lyase activity (0.29) cytoplasm (0.57) RME1 (0.20)
Score: 0.25 0.05 0.48 0.022
P-value: 1.471E+00 (RNA processing) 8.245E-02 (hydro-lyase activity) 1.015E+00 (nucleolus) 2.166E-01 (RME1)

SFF(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) AND mRRPE(1) => SimExpr(YDR429C) OR SimExpr(other) : 7 3

EXPR: (0.219) SFF (P < 0.000) mRRPE (P < 0.001) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YOL123W HRP1 mRNA cleavage, mRNA polyadenylation ->
mRNA metabolism, RNA processing cleavage/polyadenylation specificity factor activity ->
cleavage/polyadenylation specificity factor activity mRNA cleavage factor complex, nucleus ->
nucleus
YOR004W NO SYMBOL FZF1, HIR1
|YDR374C| NO SYMBOL RME1
YDR429C TIF35 translational initiation ->
protein biosynthesis translation initiation factor activity ->
translation initiation factor activity eukaryotic translation initiation factor 3 complex ->
cytoplasm RFX1
|YGL029W| CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus
YDR341C NO SYMBOL GCN4, ZMS1
YKL029C MAE1 pyruvate metabolism, amino acid metabolism ->
pyruvate metabolism, amino acid metabolism malate dehydrogenase (oxaloacetate decarboxylating) activity ->
malate dehydrogenase (oxaloacetate decarboxylating) activity mitochondrion ->
cytoplasm ABF1, CIN5
YLR175W CBF5 rRNA modification, 35S primary transcript processing ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent pseudouridylate synthase activity ->
pseudouridylate synthase activity small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex AZF1, HAL9
YML125C NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
|YOR066W| NO SYMBOL MBP1, MCM1
Main: RNA processing (0.60) translation initiation factor activity (0.25) nucleus (0.60) RME1 (0.25)
Score: 0.30 0.00 0.40 0.036
P-value: 3.992E-01 (RNA processing) 2.671E+00 (nucleic acid binding) 4.340E-01 (nucleolus) 8.817E-02 (RME1)

m_amino-acid_degradation_orfnum2SD_n8(1) AND m_g-proteins_orfnum2SD_n11(1) AND mRRPE(1) => SimExpr(YDR429C) : 5

EXPR: (0.164) m_g-proteins_orfnum2SD_n11 (P < 0.000) mRRPE (P < 0.000) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YJR016C ILV3 branched chain family amino acid biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis dihydroxy-acid dehydratase activity ->
hydro-lyase activity mitochondrion ->
cytoplasm
YLR244C MAP1 proteolysis and peptidolysis ->
catabolism, protein metabolism methionyl aminopeptidase activity ->
aminopeptidase activity, exopeptidase activity, metallopeptidase activity cytosolic ribosome (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
YDR429C TIF35 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity eukaryotic translation initiation factor 3 complex ->
cytoplasm RFX1
YDR341C NO SYMBOL GCN4, ZMS1
YLR175W CBF5 rRNA modification, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription pseudouridylate synthase activity ->
hydro-lyase activity small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex AZF1, HAL9
Main: biosynthesis (0.50) hydro-lyase activity (0.50) cytoplasm (0.75) AZF1 (0.33)
Score: 0.33 0.17 0.67 0.000
P-value: 1.761E+00 (biosynthesis) 7.214E-03 (hydro-lyase activity) 5.447E-01 (ribonucleoprotein complex) 1.697E-01 (ZMS1)

MCM1(1) AND MCB(1) => SimExpr(YKR077W) OR SimExpr(other) : 6 3

m_pentose-phosphate_pathway_orfnum2SD_n23(1) AND m_purine_and_pyrimidine_transporters_orfnum2SD_n17(1) => SimExpr(YLR257W) OR SimExpr(other) : 5 2

EXPR: (0.247) m_pentose-phosphate_pathway_orfnum2SD_n23 (P < 0.033) m_purine_and_pyrimidine_transporters_orfnum2SD_n17 (P < 0.059)

ORF SYMBOL P F C TF
YLR257W NO SYMBOL PHD1, SKN7
|YJR147W| HMS2 pseudohyphal growth ->
cell organization and biogenesis transcription factor activity ->
transcription factor activity ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YJL078C PRY3 cell wall (sensu Fungi) ->
cell wall (sensu Fungi) ACE2, CIN5, FKH1, FKH2, MET4, RAP1, SWI5
|YKR092C| SRP40 nucleocytoplasmic transport ->
transport chaperone activity ->
chaperone activity nucleolus ->
nucleolus CUP9, MET4, RAP1
YML070W DAK1 glycerol catabolism, response to stress ->
response to stress, alcohol metabolism, glycerol ether metabolism, lipid metabolism, catabolism glycerone kinase activity ->
glycerone kinase activity SFP1
YGL186C TPN1 vitamin/cofactor transport ->
transport vitamin/cofactor transporter activity ->
vitamin/cofactor transporter activity plasma membrane ->
plasma membrane BAS1, SIG1, SKO1
YIL052C RPL34B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic large ribosomal subunit (sensu Eukarya) RME1
Main: transport (0.40) glycerone kinase activity (0.20) cytosolic large ribosomal subunit (sensu Eukarya) (0.25) RAP1 (0.43)
Score: 0.10 0.00 0.00 0.143
P-value: 3.053E+00 (transport) 2.000E+00 4.000E+00 (intracellular) 7.445E-02 (ACE2)

m_pentose-phosphate_pathway_orfnum2SD_n23(1) AND m_lipid_and_fatty-acid_transport_orfnum2SD_n11(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YLR257W) : 5

EXPR: (0.181) m_lipid_and_fatty-acid_transport_orfnum2SD_n11 (P < 0.000) m_anion_transporters_orfnum2SD_n15 (P < 0.001) m_pentose-phosphate_pathway_orfnum2SD_n23 (P < 0.003)

ORF SYMBOL P F C TF
YLR257W NO SYMBOL PHD1, SKN7
YOR343C NO SYMBOL DIG1, RAP1, STE12
YJL078C PRY3 cell wall (sensu Fungi) ->
cell wall (sensu Fungi) ACE2, CIN5, FKH1, FKH2, MET4, RAP1, SWI5
YPL111W CAR1 arginine catabolism to ornithine ->
arginine catabolism to ornithine arginase activity ->
arginase activity cytosol ->
cytosol GCN4
YIL052C RPL34B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome RME1
Main: arginine catabolism to ornithine (0.50) structural constituent of ribosome (0.50) cytosol (0.67) RAP1 (0.40)
Score: 0.00 0.00 0.33 0.100
P-value: 3.848E+00 (metabolism) 2.000E+00 5.999E-01 (cytosol) 4.199E-01 (RAP1)

m_regulation_of_nucleotide_metabolism_orfnum2SD_n5(1) AND m_glyoxylate_cycle_orfnum2SD_n7(1) => SimExpr(YPL218W) OR SimExpr(other) : 5 1

EXPR: (0.176) m_regulation_of_nucleotide_metabolism_orfnum2SD_n5 (P < 0.002) m_glyoxylate_cycle_orfnum2SD_n7 (P < 0.000)

ORF SYMBOL P F C TF
|YMR272C| SCS7 fatty acid metabolism ->
fatty acid metabolism oxidoreductase activity ->
oxidoreductase activity endoplasmic reticulum ->
cytoplasm IXR1, SUM1
YKR042W UTH1 mitochondrion organization and biogenesis ->
mitochondrion organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
YNL162W RPL42A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1, YAP5
YPL218W SAR1 ER to Golgi transport ->
ER to Golgi transport SAR small monomeric GTPase activity ->
SAR small monomeric GTPase activity COPII vesicle coat ->
cytoplasm
YOR312C RPL20B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, FKH2, GAT3, RAP1
YKR013W PRY2 SWI4, SWI6
Main: protein biosynthesis (0.40) structural constituent of ribosome (0.50) cytoplasm (1.00) SWI4 FKH2 RAP1 FHL1 (0.40)
Score: 0.10 0.17 1.00 0.300
P-value: 1.478E+00 (protein biosynthesis) 2.466E-01 (structural constituent of ribosome) 8.553E-02 (cytosolic large ribosomal subunit (sensu Eukarya)) 2.046E-01 (FKH2)

SFF(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) AND m_lipid_and_fatty-acid_transport_orfnum2SD_n11(1) => SimExpr(YMR145C) OR SimExpr(other) : 5 1

EXPR: (0.197) SFF (P < 0.001) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.004) m_lipid_and_fatty-acid_transport_orfnum2SD_n11 (P < 0.001)

ORF SYMBOL P F C TF
YNL320W NO SYMBOL
|YKL001C| MET14 sulfate assimilation, methionine metabolism ->
sulfur utilization, amine metabolism, sulfur metabolism, amino acid and derivative metabolism, carboxylic acid metabolism adenylylsulfate kinase activity ->
adenylylsulfate kinase activity cell ->
cell GAT3, MET31, MET4, RGM1, SIP4
YMR145C NDE1 ethanol fermentation, NADH oxidation ->
ethanol metabolism, coenzyme metabolism, energy derivation by oxidation of organic compounds, water-soluble vitamin metabolism NADH dehydrogenase activity ->
NADH dehydrogenase activity mitochondrion ->
cell SWI4
YDL078C MDH3 glyoxylate cycle, malate metabolism, fatty acid beta-oxidation, NADH regeneration ->
aldehyde metabolism, carbohydrate metabolism, lipid metabolism, coenzyme metabolism, carboxylic acid metabolism, water-soluble vitamin metabolism, energy derivation by oxidation of organic compounds malic enzyme activity ->
malic enzyme activity peroxisomal matrix ->
cell MIG1
YHR195W NVJ1 microautophagy ->
microautophagy protein binding ->
protein binding nuclear membrane ->
cell ACE2, MBP1, NRG1, SMP1
YDL128W VCX1 calcium ion transport, calcium ion homeostasis ->
cell ion homeostasis, ion transport, cation homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cell MAC1, STE12
Main: coenzyme metabolism (0.40) protein binding (0.20) cell (1.00) SWI4 (0.20)
Score: 0.20 0.00 1.00 0.000
P-value: 1.338E-03 (NADH metabolism) 3.603E-01 (oxidoreductase activity) 2.499E+00 (membrane) 7.529E-01 (RGM1)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8(1) => SimExpr(YPR065W) OR SimExpr(other) : 7 1

EXPR: (0.204) m_c-compound_and_carbohydrate_metabolism_orfnum2SD_n8 (P < 0.009) m_other_signal-transduction_activities_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
carbon-oxygen lyase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YPR065W ROX1 negative regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription DNA bending activity, specific transcriptional repressor activity ->
DNA binding, specific transcriptional repressor activity nuclear chromosome ->
chromosome, nucleus CIN5, HAP4, PHD1, SKN7, YAP1, YAP6
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
|YHR138C| NO SYMBOL ADR1, ARO80, FZF1, HIR1, IME4, NRG1, PDR1, RCS1, SKN7, SRD1, STB1, SWI5, YAP3, YAP7, YFL044C
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups
YGR122W NO SYMBOL CIN5
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
transferase activity\, transferring phosphorus-containing groups MTH1
Main: alcohol metabolism (0.50) transferase activity\, transferring phosphorus-containing groups (0.33) cytoplasm (0.75) SKN7 SWI5 (0.43)
Score: 0.60 0.07 0.50 0.286
P-value: 1.001E-02 (glucose metabolism) 7.127E-01 (transferase activity\, transferring phosphorus-containing groups) 4.664E+00 (cytoplasm) 1.890E-02 (SWI5)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_biogenesis_of_chromosome_structure_orfnum2SD_n18(1) => SimExpr(YGL121C) OR SimExpr(other) : 5 2

EXPR: (0.208) m_other_signal-transduction_activities_orfnum2SD_n8 (P < 0.001) m_biogenesis_of_chromosome_structure_orfnum2SD_n18 (P < 0.001)

ORF SYMBOL P F C TF
YNL187W NO SYMBOL DOT6, RGT1
|YGR088W| CTT1 response to stress ->
response to stress catalase activity ->
catalase activity cytoplasm ->
cytoplasm
YOR377W ATF1 fermentation ->
fermentation alcohol O-acetyltransferase activity ->
alcohol O-acetyltransferase activity cell fraction ->
cell fraction
YGL121C GPG1 signal transduction ->
signal transduction signal transducer activity ->
signal transducer activity CHA4
YMR020W FMS1 pantothenate biosynthesis, polyamine catabolism ->
pantothenate biosynthesis, polyamine catabolism amine oxidase (flavin-containing) activity, amine oxidase activity ->
amine oxidase (flavin-containing) activity, amine oxidase activity cytoplasm ->
cytoplasm PHD1
YML018C NO SYMBOL
|YNL217W| NO SYMBOL CIN5, SOK2
Main: response to stress (0.25) catalase activity (0.25) cytoplasm (0.67) SOK2 (0.25)
Score: 0.00 0.00 0.33 0.000
P-value: 3.979E+00 (metabolism) 3.837E-01 (oxidoreductase activity) 4.869E+00 (cytoplasm) 4.035E-01 (RGT1)

m_phosphate_utilization_orfnum2SD_n9(1) AND m_meiosis_orfnum2SD_n3(1) => SimExpr(YKR005C) : 5

ndt80(MSE)(1) AND m_metal_ion_transporters_orfnum2SD_n26(1) => SimExpr(YKR005C) : 5

EXPR: (0.158) m_metal_ion_transporters_orfnum2SD_n26 (P < 0.000) ndt80(MSE) (P < 0.001)

ORF SYMBOL P F C TF
YDR042C NO SYMBOL ARG80, ARG81, AZF1, CIN5, CUP9, DIG1, FZF1, GCR2, HAL9, HAP2, HAP4, HAP5, HIR2, HMS1, IXR1, LEU3, MBP1, MCM1, MET31, NRG1, PDR1, RLM1, RME1, ROX1, RTG1, RTG3, SRD1, STE12, SUM1, YAP6, ZAP1
YKR005C NO SYMBOL
YOR338W NO SYMBOL RAP1
YFR012W NO SYMBOL DAL81
YHL043W ECM34 cell wall organization and biogenesis ->
cell wall organization and biogenesis
Main: cell wall organization and biogenesis (1.00) GCR2 (0.33)
Score: 0.00 0.000
P-value: 0.000E+00 1.000E+00

m_c-compound_and_carbohydrate_utilization_orfnum2SD_n31(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YGR212W) OR SimExpr(other) : 5 2

m_drug_transporters_orfnum2SD_n9(1) AND m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n13(1) => SimExpr(YGL253W) OR SimExpr(other) : 5 1

EXPR: (0.199) m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n13 (P < 0.001) m_drug_transporters_orfnum2SD_n9 (P < 0.002)

ORF SYMBOL P F C TF
YAR068W NO SYMBOL MAL13, MTH1
YHR097C NO SYMBOL
YDR134C NO SYMBOL ASH1, NRG1, SOK2, SWI4
|YMR042W| ARG80 positive regulation of transcription from Pol II promoter, arginine metabolism ->
positive regulation of transcription from Pol II promoter, arginine metabolism DNA binding, specific RNA polymerase II transcription factor activity ->
DNA binding, specific RNA polymerase II transcription factor activity nucleus ->
nucleus RME1
YGR055W MUP1 sulfur amino acid transport ->
sulfur amino acid transport L-methionine porter activity ->
L-methionine porter activity integral to plasma membrane ->
integral to plasma membrane DAL81, INO4, MET4, STP1
YGL253W HXK2 fructose metabolism ->
fructose metabolism hexokinase activity ->
hexokinase activity nucleus, cytosol ->
nucleus, cytosol ABF1, CIN5, HSF1, SWI4
Main: arginine metabolism (0.33) DNA binding (0.33) nucleus (0.67) SWI4 (0.40)
Score: 0.00 0.00 0.33 0.100
P-value: 3.943E+00 (metabolism) 2.000E+00 3.428E+00 (nucleus) 3.429E-01 (SWI4)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n13(1) => SimExpr(YGL253W) OR SimExpr(other) : 6 3

EXPR: (0.237) m_regulation_of_nitrogen_and_sulphur_utilization_orfnum2SD_n13 (P < 0.009) m_other_signal-transduction_activities_orfnum2SD_n8 (P < 0.001)

ORF SYMBOL P F C TF
YAR068W NO SYMBOL MAL13, MTH1
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
|YLR329W| REC102 meiotic recombination, meiotic DNA double-strand break formation ->
cell proliferation, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA binding ->
DNA binding nucleus ->
nucleus
|YGR100W| MDR1 Rab GTPase activator activity ->
small GTPase regulatory/interacting protein activity soluble fraction ->
soluble fraction CHA4, IXR1
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups
YDR134C NO SYMBOL ASH1, NRG1, SOK2, SWI4
|YIR016W| NO SYMBOL DAL82, RAP1
YLR293C GSP1 nucleocytoplasmic transport, nuclear organization and biogenesis, rRNA processing ->
transport, cell organization and biogenesis, RNA metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RAN small monomeric GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm, nucleus ->
cytoplasm, nucleus ABF1
YGL253W HXK2 fructose metabolism ->
alcohol metabolism, carbohydrate metabolism hexokinase activity ->
carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups nucleus, cytosol ->
nucleus, cytoplasm ABF1, CIN5, HSF1, SWI4
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.60) transferase activity\, transferring phosphorus-containing groups (0.33) cytoplasm (0.60) ABF1 SWI4 (0.29)
Score: 0.60 0.07 0.50 0.095
P-value: 4.098E-01 (hexose metabolism) 1.041E+00 (transferase activity\, transferring phosphorus-containing groups) 1.878E+00 (cytosol) 7.566E-01 (SWI4)

m_ion_transporters_orfnum2SD_n10(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YOR316C) OR SimExpr(other) : 5 2

EXPR: (0.198) m_ion_transporters_orfnum2SD_n10 (P < 0.015) m_anion_transporters_orfnum2SD_n20 (P < 0.002)

m_metal_ion_transporters_orfnum2SD_n10(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YOR316C) OR SimExpr(other) : 5 2

EXPR: (0.201) m_metal_ion_transporters_orfnum2SD_n10 (P < 0.000) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.001)

ORF SYMBOL P F C TF
YNR067C DSE4 cytokinesis\, completion of separation ->
cytokinesis glucan 1\,3-beta-glucosidase activity ->
glucan 1\,3-beta-glucosidase activity septum, extracellular ->
septum, extracellular YAP6
|YOL019W| NO SYMBOL SWI4
YPR147C NO SYMBOL
YOR316C COT1 cobalt ion transport, zinc ion transport, zinc ion homeostasis ->
cell ion homeostasis, ion transport, cation homeostasis di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity ->
di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity vacuole (sensu Fungi) ->
cytoplasm FKH2, INO2, INO4, NDD1, RAP1
YJL048C NO SYMBOL INO4, MAC1, MET4, SKN7
YKL190W CNB1 cell ion homeostasis, cell wall organization and biogenesis, adaptation to pheromone during conjugation with cellular fusion ->
cell ion homeostasis, external encapsulating structure organization and biogenesis, conjugation with cellular fusion, perception of abiotic stimulus, sensory perception calcium-dependent protein serine/threonine phosphatase activity ->
calcium-dependent protein serine/threonine phosphatase activity cytoplasm ->
cytoplasm ABF1
|YOL159C| NO SYMBOL ARO80, CIN5, RLM1
Main: cell ion homeostasis (0.67) cobalt ion transporter activity (0.33) cytoplasm (0.67) INO4 (0.33)
Score: 0.33 0.00 0.33 0.067
P-value: 6.473E-02 (cell ion homeostasis) 1.611E+00 (hydrolase activity) 4.869E+00 (cytoplasm) 2.125E-01 (INO4)

m_other_signal-transduction_activities_orfnum2SD_n8(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YOR316C) OR SimExpr(other) : 7 3

m_homeostasis_of_metal_ions_orfnum2SD_n20(1) AND m_other_cation_transporters_orfnum2SD_n3(1) => SimExpr(YOR316C) OR SimExpr(other) : 7 2

m_other_energy_generation_activities_orfnum2SD_n16(1) AND m_other_cell_rescue_activities_orfnum2SD_n10(1) => SimExpr(YKL186C) OR SimExpr(other) : 5 1

SFF(1) AND m_cell_death_orfnum2SD_n16(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn(1) => SimExpr(YLR414C) OR SimExpr(other) : 6 2

EXPR: (0.212) SFF (P < 0.000) m_cell_death_orfnum2SD_n16 (P < 0.000) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n16.scn (P < 0.001)

m_metal_ion_transporters_orfnum2SD_n10(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YNR067C) OR SimExpr(other) : 5 2

m_other_mrna-transcription_activities_orfnum2SD_n20(1) AND m_nitrogen_and_sulphur_utilization_orfnum2SD_n4(1) => SimExpr(YOL158C) OR SimExpr(other) : 5 2

EXPR: (0.218) m_nitrogen_and_sulphur_utilization_orfnum2SD_n4 (P < 0.004) m_other_mrna-transcription_activities_orfnum2SD_n20 (P < 0.005)

ORF SYMBOL P F C TF
|YGR244C| LSC2 tricarboxylic acid cycle, succinyl-CoA metabolism ->
carbohydrate metabolism, coenzymes and prosthetic group metabolism, energy pathways succinate-CoA ligase (ADP-forming) activity ->
succinate-CoA ligase (ADP-forming) activity mitochondrion ->
cytoplasm ARO80
|YML130C| ERO1 protein folding, protein thiol-disulfide exchange ->
protein metabolism electron carrier activity ->
electron carrier activity endoplasmic reticulum ->
cytoplasm YAP1
YGL197W MDS3 sporulation ->
sporulation cytoplasm ->
cytoplasm MTH1
YPL219W PCL8 regulation of glycogen catabolism, regulation of glycogen biosynthesis ->
carbohydrate metabolism, catabolism, biosynthesis, polysaccharide metabolism, energy pathways, regulation of metabolism cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transketolase activity cytoplasm ->
cytoplasm REB1
YOL158C ENB1 ferric-enterobactin transport ->
transport ferric-enterobactin transporter activity ->
ferric-enterobactin transporter activity integral to membrane, cytoplasmic vesicle, endosome ->
integral to membrane, cytoplasm RAP1, YAP6
YOR153W PDR5 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane YAP6
Main: carbohydrate metabolism (0.43) cyclin-dependent protein kinase\, regulator activity (0.17) cytoplasm (0.71) YAP6 (0.33)
Score: 0.19 0.00 0.48 0.067
P-value: 5.123E-02 (energy pathways) 1.907E-01 (carrier activity) 2.186E+00 (cytoplasm) 1.378E-01 (YAP6)

m_nitrogen_and_sulphur_transport_orfnum2SD_n9(1) AND m_other_cation_transporters_orfnum2SD_n18(1) => SimExpr(YOL158C) OR SimExpr(other) : 5 2

EXPR: (0.209) m_nitrogen_and_sulphur_transport_orfnum2SD_n9 (P < 0.001) m_other_cation_transporters_orfnum2SD_n18 (P < 0.000)

m_c-compound_and_carbohydrate_utilization_orfnum2SD_n31(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YIL124W) OR SimExpr(other) : 6 1

m_g-proteins_orfnum2SD_n12(1) AND m_other_cation_transporters_orfnum2SD_n14(1) AND SCB(1) => SimExpr(YMR291W) OR SimExpr(other) : 5 2

EXPR: (0.208) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_other_cation_transporters_orfnum2SD_n14 (P < 0.006) SCB (P < 0.001)

ORF SYMBOL P F C TF
|YIL118W| RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
signal transduction, cell organization and biogenesis, transport Rho small monomeric GTPase activity, signal transducer activity ->
GTP binding, signal transducer activity, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YAR018C KIN3 chromosome segregation ->
cell proliferation protein kinase activity ->
protein kinase activity FKH2, MCM1, MSS11, NDD1
YMR291W NO SYMBOL RAP1
YDL185W TFP1 intron homing, vacuolar acidification, protein metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell homeostasis, protein metabolism, cell organization and biogenesis, transport hydrogen-exporting ATPase activity, endodeoxyribonuclease activity ->
ATP binding, deoxyribonuclease activity, hydrogen ion transporter activity, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides, endonuclease activity vacuolar membrane (sensu Fungi), hydrogen-transporting ATPase V1 domain ->
intracellular SWI4
YGR204W ADE3 purine base biosynthesis ->
aromatic compound metabolism, biosynthesis, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism formate-tetrahydrofolate ligase activity ->
formate-tetrahydrofolate ligase activity cytoplasm ->
intracellular ABF1, BAS1, CBF1, MET31, MET4
YDL079C MRK1 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis ->
response to stress, phosphorus metabolism, catabolism, protein metabolism glycogen synthase kinase 3 activity ->
protein kinase activity MTH1
|YIL125W| KGD1 tricarboxylic acid cycle, 2-oxoglutarate metabolism ->
carbohydrate metabolism, ketone metabolism, organic acid metabolism, energy pathways oxoglutarate dehydrogenase (lipoamide) activity ->
oxoglutarate dehydrogenase (lipoamide) activity mitochondrial matrix ->
intracellular REB1, UGA3
Main: cell organization and biogenesis (0.33) protein kinase activity (0.33) intracellular (1.00) ABF1 (0.14)
Score: 0.20 0.13 1.00 0.000
P-value: 2.904E+00 (organelle organization and biogenesis) 5.903E-01 (protein kinase activity) 4.385E+00 (cytoplasm) 1.000E+00

MCM1(1) AND m_nutritional_response_pathway_orfnum2SD_n8(1) => SimExpr(YMR291W) OR SimExpr(other) : 8 3

EXPR: (0.209) MCM1 (P < 0.001) m_nutritional_response_pathway_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YOR025W HST3 chromatin silencing at telomere, short-chain fatty acid metabolism ->
cell organization and biogenesis, lipid metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription, organic acid metabolism DNA binding ->
DNA binding nucleus ->
nucleus IXR1, NDD1
|YAR020C| PAU7
YMR070W MOT3 transcription ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcriptional repressor activity, DNA binding, transcriptional activator activity ->
transcriptional repressor activity, DNA binding, transcriptional activator activity nucleus ->
nucleus BAS1, CUP9, HSF1, INO2, INO4, SWI4
YDR293C SSD1 cell wall organization and biogenesis ->
cell organization and biogenesis RNA binding ->
RNA binding cytoplasm ->
cytoplasm
YOL087C NO SYMBOL DAL82
|YGR280C| PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YOR010C TIR2 response to stress ->
response to stress cell wall ->
cell wall NRG1
YAR018C KIN3 chromosome segregation ->
cell proliferation protein kinase activity ->
protein kinase activity FKH2, MCM1, MSS11, NDD1
YMR291W NO SYMBOL RAP1
|YML088W| UFO1 response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism ubiquitin-protein ligase activity ->
ubiquitin-protein ligase activity HAP4, RAP1, SKN7
YML085C TUB1 homologous chromosome segregation, mitotic chromosome segregation, nuclear migration during conjugation with cellular fusion, nuclear migration (sensu Saccharomyces) ->
nuclear membrane fusion, cell organization and biogenesis, cell cycle, conjugation, sexual reproduction structural constituent of cytoskeleton ->
structural constituent of cytoskeleton cytoplasmic microtubule, polar microtubule, kinetochore microtubule, nuclear microtubule, spindle pole body ->
cytoskeleton, cytoplasm STP2
Main: cell organization and biogenesis (0.50) RNA binding (0.29) nucleus (0.50) RAP1 NDD1 (0.25)
Score: 0.29 0.10 0.27 0.071
P-value: 1.423E-01 (chromosome segregation) 7.267E-01 (nucleic acid binding) 4.831E+00 (nucleus) 6.637E-01 (NDD1)

m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND mRRPE(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) => SimExpr(YML125C) OR SimExpr(other) : 5 2

MCM1'(1) AND m_metal_ion_transporters_orfnum2SD_n17(1) AND SWI5(1) => SimExpr(YFL016C) OR SimExpr(other) : 5 2

EXPR: (0.220) m_metal_ion_transporters_orfnum2SD_n17 (P < 0.011) SWI5 (P < 0.002) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
|YHR097C| NO SYMBOL
YPR173C VPS4 protein-Golgi retention, late endosome to vacuole transport ->
cytoplasm organization and biogenesis, intracellular protein transport, secretory pathway, intracellular transport, vesicle-mediated transport, protein metabolism ATPase activity ->
ATPase activity cytoplasm, endoplasmic reticulum ->
cytoplasm
|YLR369W| SSQ1 DNA dependent DNA replication, intracellular iron ion storage ->
cell cycle, cell ion homeostasis, mitotic cell cycle, DNA metabolism chaperone activity ->
chaperone activity mitochondrial matrix ->
cytoplasm NDD1, PHD1, RME1
YFL016C MDJ1 protein folding, proteolysis and peptidolysis ->
protein folding, macromolecule catabolism, protein metabolism chaperone activity ->
chaperone activity mitochondrial inner membrane ->
cytoplasm, inner membrane HSF1, RAP1
YLR178C TFS1 regulation of proteolysis and peptidolysis ->
macromolecule catabolism, regulation of catabolism, protein metabolism lipid binding, protease inhibitor activity ->
lipid binding, protease inhibitor activity soluble fraction ->
soluble fraction
YMR099C NO SYMBOL
YOR130C ORT1 arginine biosynthesis, nuclear migration (sensu Saccharomyces) ->
amine biosynthesis, cytoplasm organization and biogenesis, cell cycle, M phase, amine metabolism, urea cycle intermediate metabolism, amino acid and derivative metabolism, carboxylic acid metabolism ornithine transporter activity ->
ornithine transporter activity mitochondrial membrane ->
cytoplasm GCN4
Main: protein metabolism (0.60) chaperone activity (0.40) cytoplasm (0.80) RAP1 (0.33)
Score: 0.50 0.10 0.60 0.000
P-value: 3.918E-01 (proteolysis and peptidolysis) 2.999E-02 (chaperone activity) 3.599E-01 (mitochondrial membrane) 4.713E-01 (RME1)

m_nitrogen_and_sulphur_transport_orfnum2SD_n9(1) AND m_other_cation_transporters_orfnum2SD_n18(1) => SimExpr(YPR036W) OR SimExpr(other) : 5 2

SFF(1) AND m_lipid_and_fatty-acid_transport_orfnum2SD_n7(1) AND SWI5(1) AND m_trna_processing_orfnum2SD_n6(1) => SimExpr(YLR155C) OR SimExpr(other) : 7 1

EXPR: (0.188) SFF (P < 0.000) SWI5 (P < 0.000) m_lipid_and_fatty-acid_transport_orfnum2SD_n7 (P < 0.000) m_trna_processing_orfnum2SD_n6 (P < 0.000)

m_glyoxylate_cycle_orfnum2SD_n11(1) AND m_organization_of_cell_wall_orfnum2SD_n10(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YLR155C) OR SimExpr(other) : 5 2

EXPR: (0.203) m_phosphate_transport_orfnum2SD_n18 (P < 0.000) m_organization_of_cell_wall_orfnum2SD_n10 (P < 0.002) m_glyoxylate_cycle_orfnum2SD_n11 (P < 0.000)

m_glyoxylate_cycle_orfnum2SD_n11(1) AND SWI5(1) AND m_trna_processing_orfnum2SD_n6(1) => SimExpr(YLR155C) OR SimExpr(other) : 5 2

EXPR: (0.208) SWI5 (P < 0.000) m_glyoxylate_cycle_orfnum2SD_n11 (P < 0.000) m_trna_processing_orfnum2SD_n6 (P < 0.000)

MCM1(1) AND SFF(1) AND SWI5(1) AND m_trna_processing_orfnum2SD_n6(1) => SimExpr(YLR155C) OR SimExpr(other) : 5 2

EXPR: (0.194) SFF (P < 0.000) SWI5 (P < 0.000) MCM1 (P < 0.000) m_trna_processing_orfnum2SD_n6 (P < 0.000)

m_amino-acid_degradation_orfnum2SD_n24(1) AND m_organization_of_cell_wall_orfnum2SD_n10(1) => SimExpr(YLR155C) OR SimExpr(other) : 5 1

EXPR: (0.192) m_amino-acid_degradation_orfnum2SD_n24 (P < 0.000) m_organization_of_cell_wall_orfnum2SD_n10 (P < 0.001)

m_chromatin_modification_orfnum2SD_n21(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YLR155C) OR SimExpr(other) : 6 2

EXPR: (0.198) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.000) m_chromatin_modification_orfnum2SD_n21 (P < 0.000)

m_amino-acid_degradation_orfnum2SD_n29(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YLR155C) OR SimExpr(other) : 5 2

EXPR: (0.202) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.000) m_amino-acid_degradation_orfnum2SD_n29 (P < 0.002)

m_amino-acid_degradation_orfnum2SD_n29(1) AND m_organization_of_chromosome_structure_orfnum2SD_n17(1) => SimExpr(YLR155C) OR SimExpr(other) : 5 2

EXPR: (0.219) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.000) m_amino-acid_degradation_orfnum2SD_n29 (P < 0.002)

m_chromatin_modification_orfnum2SD_n21(1) AND m_fermentation_orfnum2SD_n14(1) => SimExpr(YLR155C) OR SimExpr(other) : 5 1

EXPR: (0.191) m_chromatin_modification_orfnum2SD_n21 (P < 0.001) m_fermentation_orfnum2SD_n14 (P < 0.002)

m_g-proteins_orfnum2SD_n11(1) AND m_lipid_and_fatty-acid_transport_orfnum2SD_n7(1) AND m_trna_processing_orfnum2SD_n6(1) => SimExpr(YLR155C) OR SimExpr(other) : 5 1

EXPR: (0.198) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_lipid_and_fatty-acid_transport_orfnum2SD_n7 (P < 0.000) m_trna_processing_orfnum2SD_n6 (P < 0.000)

m_chromatin_modification_orfnum2SD_n21(1) AND m_g-proteins_orfnum2SD_n11(1) AND m_fermentation_orfnum2SD_n14(1) => SimExpr(YLR155C) : 5

EXPR: (0.156) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_chromatin_modification_orfnum2SD_n21 (P < 0.000) m_fermentation_orfnum2SD_n14 (P < 0.001)

m_g-proteins_orfnum2SD_n11(1) AND m_fermentation_orfnum2SD_n14(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YLR155C) : 5

EXPR: (0.156) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_anion_transporters_orfnum2SD_n15 (P < 0.000) m_fermentation_orfnum2SD_n14 (P < 0.000)

m_chromatin_modification_orfnum2SD_n21(1) AND m_g-proteins_orfnum2SD_n11(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YLR155C) : 5

EXPR: (0.159) m_g-proteins_orfnum2SD_n11 (P < 0.000) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.000) m_chromatin_modification_orfnum2SD_n21 (P < 0.000)

MCM1'(1) AND m_chromatin_modification_orfnum2SD_n21(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YLR155C) : 5

EXPR: (0.159) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.000) m_chromatin_modification_orfnum2SD_n21 (P < 0.000) MCM1' (P < 0.000)

MCM1'(1) AND m_amino-acid_degradation_orfnum2SD_n24(1) AND m_organization_of_cell_wall_orfnum2SD_n10(1) => SimExpr(YLR155C) : 5

EXPR: (0.159) m_amino-acid_degradation_orfnum2SD_n24 (P < 0.000) m_organization_of_cell_wall_orfnum2SD_n10 (P < 0.000) MCM1' (P < 0.000)

SFF(1) AND m_chromatin_modification_orfnum2SD_n21(1) AND m_fermentation_orfnum2SD_n14(1) => SimExpr(YLR155C) : 5

EXPR: (0.156) SFF (P < 0.000) m_chromatin_modification_orfnum2SD_n21 (P < 0.000) m_fermentation_orfnum2SD_n14 (P < 0.000)

m_chromatin_modification_orfnum2SD_n21(1) AND SWI5(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YLR155C) : 6

EXPR: (0.166) SWI5 (P < 0.000) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.000) m_chromatin_modification_orfnum2SD_n21 (P < 0.000)

m_drug_transporters_orfnum2SD_n9(1) AND MCM1(1) AND m_g-proteins_orfnum2SD_n11(1) => SimExpr(YLR155C) : 5

EXPR: (0.161) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_drug_transporters_orfnum2SD_n9 (P < 0.001) MCM1 (P < 0.000)

m_amino-acid_degradation_orfnum2SD_n29(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YLR157C) OR SimExpr(other) : 5 2

m_amino-acid_degradation_orfnum2SD_n29(1) AND m_organization_of_chromosome_structure_orfnum2SD_n17(1) => SimExpr(YLR157C) OR SimExpr(other) : 5 2

m_chromatin_modification_orfnum2SD_n21(1) AND m_fermentation_orfnum2SD_n14(1) => SimExpr(YLR157C) OR SimExpr(other) : 5 1

MCM1'(1) AND m_fermentation_orfnum2SD_n14(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YLR157C) OR SimExpr(other) : 5 1

EXPR: (0.189) m_anion_transporters_orfnum2SD_n15 (P < 0.000) m_fermentation_orfnum2SD_n14 (P < 0.000) MCM1' (P < 0.000)

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) AND m_trna_processing_orfnum2SD_n6(1) => SimExpr(YLR157C) OR SimExpr(other) : 5 1

EXPR: (0.203) m_organization_of_chromosome_structure_orfnum2SD_n17 (P < 0.000) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.000) m_trna_processing_orfnum2SD_n6 (P < 0.000)

m_amino-acid_degradation_orfnum2SD_n24(1) AND m_glyoxylate_cycle_orfnum2SD_n11(1) AND m_g-proteins_orfnum2SD_n11(1) => SimExpr(YLR157C) OR SimExpr(other) : 5 2

EXPR: (0.219) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_amino-acid_degradation_orfnum2SD_n24 (P < 0.002) m_glyoxylate_cycle_orfnum2SD_n11 (P < 0.000)

m_amino-acid_degradation_orfnum2SD_n24(1) AND m_amino-acid_degradation_orfnum2SD_n29(1) AND m_g-proteins_orfnum2SD_n11(1) => SimExpr(YLR157C) : 6

EXPR: (0.179) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_amino-acid_degradation_orfnum2SD_n24 (P < 0.000) m_amino-acid_degradation_orfnum2SD_n29 (P < 0.000)

m_drug_transporters_orfnum2SD_n9(1) AND MCM1(1) AND m_g-proteins_orfnum2SD_n11(1) => SimExpr(YLR157C) : 5

MCM1'(1) AND HAP234(1) => SimExpr(YDR377W) OR SimExpr(other) : 9 4

MCM1'(1) AND SFF(1) AND HAP234(1) => SimExpr(YDR377W) OR SimExpr(other) : 6 1

MCM1'(1) AND m_anion_transporters_orfnum2SD_n15(1) AND HAP234(1) => SimExpr(YDR377W) OR SimExpr(other) : 5 1

EXPR: (0.209) m_anion_transporters_orfnum2SD_n15 (P < 0.001) HAP234 (P < 0.038) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YMR143W RPS16A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, YAP5
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane HAP4
YLR304C ACO1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis aconitate hydratase activity ->
aconitate hydratase activity cytosol, mitochondrial matrix ->
cytoplasm CIN5, YAP6
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
oxidoreductase activity\, acting on diphenols and related substances as donors\, cytochrome as acceptor, primary active transporter activity, hydrogen ion transporter activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
|YKL198C| PTK1 polyamine transport ->
transport protein kinase activity ->
protein kinase activity INO2
YDR377W ATP17 ATP synthesis coupled proton transport ->
transport hydrogen-transporting ATP synthase activity ->
hydrogen ion transporter activity proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane ARO80, HAP2, HAP3, HAP4, RPH1
Main: transport (0.50) hydrogen ion transporter activity (0.40) cytoplasm (1.00) HAP4 (0.50)
Score: 0.33 0.10 1.00 0.200
P-value: 4.400E-03 (ATP synthesis coupled proton transport) 1.245E-02 (hydrogen ion transporter activity) 5.537E-03 (proton-transporting ATP synthase complex) 7.074E-04 (HAP4)

MCM1'(1) AND SFF'(1) AND HAP234(1) => SimExpr(YDR377W) OR SimExpr(other) : 7 2

EXPR: (0.210) SFF' (P < 0.000) HAP234 (P < 0.022) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
|YPL177C| CUP9 copper ion homeostasis, transcription initiation from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell homeostasis, transcription specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus BAS1, CIN5, MAC1, PHD1, SWI4, YAP6
YNL069C RPL16B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YMR143W RPS16A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, YAP5
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane HAP4
YPR035W GLN1 nitrogen metabolism, glutamine biosynthesis ->
nitrogen metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis glutamate-ammonia ligase activity ->
ammonia ligase activity cytoplasm ->
cytoplasm CIN5, DAL81, FKH1, FKH2, GLN3, HSF1, INO4, MSN1, REB1, SWI4
YFR033C QCR6 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
oxidoreductase activity\, acting on diphenols and related substances as donors\, cytochrome as acceptor, primary active transporter activity, hydrogen ion transporter activity mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane HAP4, MBP1
|YJL079C| PRY1 nuclear membrane, endoplasmic reticulum ->
nucleus, cytoplasm, endomembrane system NDD1, PHD1, RAP1
YDR377W ATP17 ATP synthesis coupled proton transport ->
transport hydrogen-transporting ATP synthase activity ->
hydrogen ion transporter activity proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane ARO80, HAP2, HAP3, HAP4, RPH1
YDL140C RPO21 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase II\, core complex ->
nucleus REB1
Main: biosynthesis (0.38) hydrogen ion transporter activity (0.29) cytoplasm (0.78) RAP1 HAP4 (0.33)
Score: 0.18 0.10 0.67 0.250
P-value: 1.358E-02 (ATP synthesis coupled proton transport) 3.666E-02 (hydrogen ion transporter activity) 1.649E-02 (proton-transporting ATP synthase complex) 5.566E-03 (HAP4)

MCM1'(1) AND m_other_morphogenetic_activities_orfnum2SD_n7(1) AND HAP234(1) => SimExpr(YDR377W) OR SimExpr(other) : 5 1

EXPR: (0.199) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) HAP234 (P < 0.026) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YMR143W RPS16A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, RGM1, YAP5
YPR035W GLN1 nitrogen metabolism, glutamine biosynthesis ->
nitrogen metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis glutamate-ammonia ligase activity ->
glutamate-ammonia ligase activity cytoplasm ->
cytoplasm CIN5, DAL81, FKH1, FKH2, GLN3, HSF1, INO4, MSN1, REB1, SWI4
|YNL040W| NO SYMBOL FZF1, GCR2, RTG3, YAP7
YDR377W ATP17 ATP synthesis coupled proton transport ->
transport hydrogen-transporting ATP synthase activity ->
hydrogen-transporting ATP synthase activity proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane ARO80, HAP2, HAP3, HAP4, RPH1
YDL140C RPO21 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase II\, core complex ->
nucleus REB1
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
ARF small monomeric GTPase activity Golgi vesicle, cytosol ->
cytoplasm, Golgi apparatus MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: biosynthesis (0.40) ARF small monomeric GTPase activity (0.20) cytoplasm (0.80) REB1 (0.50)
Score: 0.20 0.00 0.60 0.200
P-value: 2.848E+00 (transport) 2.077E+00 (enzyme activity) 8.352E-01 (cytosol) 2.887E-02 (REB1)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) => SimExpr(YGR183C) OR SimExpr(other) : 6 2

EXPR: (0.202) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.001) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.001)

ORF SYMBOL P F C TF
|YOL123W| HRP1 mRNA cleavage, mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cleavage/polyadenylation specificity factor activity ->
cleavage/polyadenylation specificity factor activity mRNA cleavage factor complex, nucleus ->
nucleus
YMR141C NO SYMBOL
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
|YDL078C| MDH3 glyoxylate cycle, malate metabolism, fatty acid beta-oxidation, NADH regeneration ->
aldehyde metabolism, carbohydrate metabolism, lipid metabolism, coenzymes and prosthetic group metabolism, organic acid metabolism, vitamin metabolism, energy pathways malic enzyme activity ->
malic enzyme activity peroxisomal matrix ->
cytoplasm MIG1
YGR183C QCR9 aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c, iron-sulfur cluster assembly ->
energy pathways, electron transport, coenzymes and prosthetic group metabolism, phosphorus metabolism ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane ABF1, BAS1, HAP2, HAP4
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
YNL231C PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
YOR264W DSE3 SWI5
Main: cell organization and biogenesis (0.33) protein transporter activity (0.17) cytoplasm (0.67) SWI5 (0.33)
Score: 0.33 0.00 0.47 0.067
P-value: 1.775E-01 (coenzyme metabolism) 3.379E-01 (transporter activity) 4.060E+00 (membrane) 1.759E-01 (SWI5)

ABF1(1) AND ALPHA1'(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YMR204C) OR SimExpr(other) : 6 2

EXPR: (0.223) ABF1 (P < 0.000) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.001) ALPHA1' (P < 0.000)

m_other_energy_generation_activities_orfnum2SD_n22(1) AND CSRE(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YPL260W) OR SimExpr(other) : 5 2

EXPR: (0.207) m_phosphate_transport_orfnum2SD_n18 (P < 0.000) CSRE (P < 0.000) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.000)

ALPHA1(1) AND SFF(1) AND m_other_nutritional-response_activities_orfnum2SD_n11(1) => SimExpr(YGR220C) OR SimExpr(other) : 6 2

EXPR: (0.210) SFF (P < 0.000) ALPHA1 (P < 0.001) m_other_nutritional-response_activities_orfnum2SD_n11 (P < 0.004)

ORF SYMBOL P F C TF
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
|YLR278C| NO SYMBOL INO4, MSN1
YGR220C MRPL9 ribosomal large subunit assembly and maintenance, protein biosynthesis ->
cell organization and biogenesis, biosynthesis, protein metabolism structural constituent of ribosome, peptidyltransferase activity ->
structural constituent of ribosome, peptidyltransferase activity mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex DOT6, SRD1
|YPR005C| HAL1 salinity response, transcription initiation from Pol II promoter ->
response to abiotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm ->
cytoplasm CIN5
YOR187W TUF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity mitochondrial matrix, mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex HAP4, REB1
YKL203C TOR2 cytoskeleton organization and biogenesis, ribosome biogenesis, signal transduction, Rho protein signal transduction, regulation of cell cycle, G1 phase of mitotic cell cycle, cell cycle dependent actin filament reorganization ->
cell organization and biogenesis, signal transduction, cell cycle, cytoplasm organization and biogenesis phosphatidylinositol 3-kinase activity, protein binding ->
phosphatidylinositol 3-kinase activity, protein binding vacuolar membrane, plasma membrane ->
cytoplasm, plasma membrane BAS1, HIR1, REB1, RTG1
YNL015W PBI2 regulation of proteolysis and peptidolysis, vacuole fusion (non-autophagic) ->
cell organization and biogenesis, catabolism, protein metabolism, regulation of metabolism endopeptidase inhibitor activity ->
endopeptidase inhibitor activity cytoplasm, vacuole (sensu Fungi) ->
cytoplasm INO4
YNR001C CIT1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis citrate (SI)-synthase activity ->
citrate (SI)-synthase activity mitochondrial matrix, mitochondrion ->
cytoplasm RGM1
Main: biosynthesis (0.57) phosphopyruvate hydratase activity (0.17) cytoplasm (1.00) INO4 REB1 (0.25)
Score: 0.52 0.00 1.00 0.071
P-value: 2.682E-01 (main pathways of carbohydrate metabolism) 1.702E-01 (lyase activity) 3.392E-02 (mitochondrial matrix) 3.179E-01 (INO4)

MCM1'(1) AND m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_g-proteins_orfnum2SD_n12(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) => SimExpr(YGR222W) OR SimExpr(other) : 5 2

EXPR: (0.232) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_other_nucleotide-metabolism_activities_orfnum2SD_n17 (P < 0.002) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YMR111C NO SYMBOL GRF10(Pho2)
YGR146C NO SYMBOL HSF1
YGR222W PET54 mRNA splicing, protein biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism translation regulator activity ->
translation regulator activity mitochondrial inner membrane, mitochondrial matrix ->
cytoplasm, inner membrane SIG1, ZAP1
|YLR275W| SMD2 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism pre-mRNA splicing factor activity ->
pre-mRNA splicing factor activity small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex CRZ1, REB1
|YPL075W| GCR1 positive regulation of transcription from Pol II promoter, positive regulation of glycolysis ->
catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription, regulation of metabolism DNA binding, transcriptional activator activity ->
DNA binding, transcriptional activator activity nucleus ->
nucleus RTS2
YAR023C NO SYMBOL SFL1
YLR254C NO SYMBOL ABF1, RAP1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00) DNA binding (0.33) nucleus (0.67) ABF1 (0.14)
Score: 1.00 0.00 0.33 0.000
P-value: 5.788E-02 (mRNA splicing) 1.380E+00 (nucleic acid binding) 3.853E+00 (nucleus) 5.297E-01 (ZAP1)

SFF(1) AND PAC(1) AND m_rRSE10(1) => SimExpr(YKL078W) OR SimExpr(other) : 7 3

SFF'(1) AND PAC(1) AND m_rRSE10(1) => SimExpr(YKL078W) OR SimExpr(other) : 9 3

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND SFF(1) AND PAC(1) => SimExpr(YKL078W) OR SimExpr(other) : 18 8

ECB(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n4(1) => SimExpr(YPR019W) OR SimExpr(other) : 5 2

EXPR: (0.215) ECB (P < 0.004) m_deoxyribonucleotide_metabolism_orfnum2SD_n4 (P < 0.003)

SFF(1) AND m_other_energy_generation_activities_orfnum2SD_n16(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YDR012W) OR SimExpr(other) : 5 1

EXPR: (0.165) SFF (P < 0.000) m_anion_transporters_orfnum2SD_n15 (P < 0.000) m_other_energy_generation_activities_orfnum2SD_n16 (P < 0.000)

ORF SYMBOL P F C TF
YDR012W RPL4B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex ARG80, FZF1
YOR312C RPL20B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, FKH2, GAT3, RAP1
YDR134C NO SYMBOL ASH1, NRG1, SOK2, SWI4
YGR086C PIL1 ASH1, SWI5
YOR187W TUF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity mitochondrial matrix, mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex HAP4, REB1
|YNR001C| CIT1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis citrate (SI)-synthase activity ->
citrate (SI)-synthase activity mitochondrial matrix, mitochondrion ->
cytoplasm RGM1
Main: biosynthesis (1.00) structural constituent of ribosome (0.50) cytoplasm (1.00) ASH1 (0.33)
Score: 1.00 0.17 1.00 0.067
P-value: 1.741E-01 (biosynthesis) 1.973E-01 (structural constituent of ribosome) 1.011E-01 (cytosolic large ribosomal subunit (sensu Eukarya)) 1.916E-02 (ASH1)

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_phosphate_utilization_orfnum2SD_n4(1) => SimExpr(YHR048W) OR SimExpr(other) : 6 3

EXPR: (0.246) m_phosphate_utilization_orfnum2SD_n4 (P < 0.018) m_other_morphogenetic_activities_orfnum2SD_n8 (P < 0.004)

ORF SYMBOL P F C TF
YOR031W CRS5 response to metal ion ->
response to abiotic stimulus copper ion binding ->
copper ion binding cytoplasm ->
cytoplasm
YHR003C NO SYMBOL HAP4, SWI6, THI2
YDR075W PPH3 protein amino acid dephosphorylation, nitrogen metabolism ->
phosphorus metabolism, nitrogen metabolism, protein metabolism protein phosphatase type 2A activity ->
protein phosphatase type 2A activity GTS1, MAC1, MET4
|YOR047C| STD1 signal transduction, glucose metabolism, salinity response, regulation of transcription from Pol II promoter ->
signal transduction, alcohol metabolism, response to abiotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism protein kinase activator activity ->
protein kinase activator activity nucleus, plasma membrane ->
nucleus, plasma membrane CIN5
YMR181C NO SYMBOL
|YIR029W| DAL2 allantoin catabolism ->
amine metabolism, catabolism, heterocycle metabolism allantoicase activity ->
allantoicase activity
YHR048W NO SYMBOL CAD1, NDD1, YAP1
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
|YDL128W| VCX1 calcium ion transport, calcium ion homeostasis ->
cell homeostasis, transport, cell ion homeostasis calcium ion transporter activity, calcium\:hydrogen antiporter activity ->
calcium ion transporter activity, calcium\:hydrogen antiporter activity vacuolar membrane, vacuole (sensu Fungi) ->
cytoplasm, vacuole MAC1, STE12
Main: response to abiotic stimulus (0.33) protein kinase activator activity (0.20) cytoplasm (0.67) MAC1 STE12 YAP1 THI2 (0.33)
Score: 0.13 0.00 0.33 0.267
P-value: 6.409E-01 (response to abiotic stimulus) 2.166E+00 (hydrolase activity) 3.889E+00 (membrane) 2.994E-02 (THI2)

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_pentose-phosphate_pathway_orfnum2SD_n19(1) => SimExpr(YPL028W) : 5

m_phosphate_transport_orfnum2SD_n5(1) AND RPN4(1) => SimExpr(YKL160W) OR SimExpr(other) : 5 1

m_RPE17(1) AND m_other_cation_transporters_orfnum2SD_n14(1) => SimExpr(YDR025W) OR SimExpr(other) : 5 2

m_deoxyribonucleotide_metabolism_orfnum2SD_n4(1) AND PDR(1) => SimExpr(YDR025W) OR SimExpr(other) : 5 2

EXPR: (0.226) m_deoxyribonucleotide_metabolism_orfnum2SD_n4 (P < 0.038) PDR (P < 0.012)

ORF SYMBOL P F C TF
YKR042W UTH1 mitochondrion organization and biogenesis ->
cytoplasm organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
|YDL215C| GDH2 nitrogen metabolism ->
nitrogen metabolism glutamate dehydrogenase activity ->
glutamate dehydrogenase activity soluble fraction ->
soluble fraction FKH2, GRF10(Pho2), PUT3
|YPR125W| NO SYMBOL MAC1
YFL057C AAD16 aldehyde metabolism ->
aldehyde metabolism benzyl alcohol dehydrogenase activity ->
benzyl alcohol dehydrogenase activity ACE2, YAP1
YKL141W SDH3 oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphate metabolism, energy derivation by oxidation of organic compounds succinate dehydrogenase activity ->
succinate dehydrogenase activity respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
YAL061W NO SYMBOL
YDR025W RPS11A protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity ->
cytoplasm organization and biogenesis, macromolecule biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1
Main: cytoplasm organization and biogenesis (0.40) benzyl alcohol dehydrogenase activity (0.25) cytoplasm (0.75) ACE2 FKH2 (0.40)
Score: 0.10 0.00 0.50 0.200
P-value: 3.004E+00 (cytoplasm organization and biogenesis) 4.968E-02 (oxidoreductase activity) 3.599E-01 (mitochondrial membrane) 6.661E-02 (ACE2)

m_nitrogen_and_sulphur_metabolism_orfnum2SD_n31(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YJL222W) OR SimExpr(other) : 5 2

EXPR: (0.221) m_anion_transporters_orfnum2SD_n15 (P < 0.002) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n31 (P < 0.011)

ORF SYMBOL P F C TF
YIL173W VTH1 Golgi to vacuole transport ->
Golgi to vacuole transport signal sequence binding ->
signal sequence binding MSN2, MSN4, PHD1, SWI5, YAP5
|YNL024C| NO SYMBOL GRF10(Pho2)
YNL183C NPR1 regulation of nitrogen utilization ->
regulation of nitrogen utilization kinase activity ->
kinase activity cytoplasm ->
cytoplasm ABF1
YFR015C GSY1 glycogen metabolism ->
glycogen metabolism glycogen (starch) synthase activity ->
glycogen (starch) synthase activity INO4
YML017W PSP2
YJL222W VTH2 Golgi to vacuole transport ->
Golgi to vacuole transport signal sequence binding ->
signal sequence binding
|YNL014W| HEF3 translational elongation ->
translational elongation translation elongation factor activity, ATPase activity ->
translation elongation factor activity, ATPase activity cytosolic ribosome (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex RAP1, SKN7
Main: Golgi to vacuole transport (0.40) signal sequence binding (0.40) cytoplasm (1.00) ABF1 (0.20)
Score: 0.10 0.10 1.00 0.000
P-value: 8.178E-03 (Golgi to vacuole transport) 2.185E-03 (signal sequence binding) 4.869E+00 (cytoplasm) 3.559E-01 (MSN2)

m_nitrogen_and_sulphur_transport_orfnum2SD_n5(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YJL222W) : 7

EXPR: (0.185) m_nitrogen_and_sulphur_transport_orfnum2SD_n5 (P < 0.000) m_anion_transporters_orfnum2SD_n15 (P < 0.000)

ORF SYMBOL P F C TF
YOL075C NO SYMBOL CRZ1, DAL82, SIP4
YIL173W VTH1 Golgi to vacuole transport ->
cell organization and biogenesis, transport, vesicle-mediated transport signal sequence binding ->
signal sequence binding MSN2, MSN4, PHD1, SWI5, YAP5
YJL042W MHP1 microtubule stabilization, cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton microtubule ->
microtubule CRZ1, GAL4, GAT3, PDR1, RGM1, YAP5
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
YFR015C GSY1 glycogen metabolism ->
carbohydrate metabolism, energy pathways glycogen (starch) synthase activity ->
glycogen (starch) synthase activity INO4
YJL222W VTH2 Golgi to vacuole transport ->
cell organization and biogenesis, transport, vesicle-mediated transport signal sequence binding ->
signal sequence binding
YGR116W SPT6 establishment and/or maintenance of chromatin architecture, regulation of transcription\, DNA-dependent, nucleosome assembly, RNA elongation from Pol II promoter ->
cell organization and biogenesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism Pol II transcription elongation factor activity ->
Pol II transcription elongation factor activity nucleus, transcription elongation factor complex ->
nucleus, transcription elongation factor complex CBF1, MSS11, RGT1, SIG1, SOK2
Main: cell organization and biogenesis (0.67) signal sequence binding (0.33) microtubule (0.50) YAP5 CRZ1 (0.40)
Score: 0.53 0.07 0.00 0.200
P-value: 9.140E-03 (Golgi to vacuole transport) 2.549E-03 (signal sequence binding) 4.000E+00 (intracellular) 2.331E-02 (CRZ1)

PDR(1) AND m_fermentation_orfnum2SD_n14(1) => SimExpr(YLR412W) OR SimExpr(other) : 5 2

m_abc_transporters_orfnum2SD_n5(1) AND PDR(1) => SimExpr(YGR281W) OR SimExpr(other) : 5 1

EXPR: (0.190) m_abc_transporters_orfnum2SD_n5 (P < 0.007) PDR (P < 0.002)

ORF SYMBOL P F C TF
YJR149W NO SYMBOL ACE2
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
ATPase activity, multidrug transporter activity, P-P-bond-hydrolysis-driven transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances plasma membrane ->
plasma membrane
YMR319C FET4 low affinity iron ion transport, intracellular copper ion transport ->
transport iron ion transporter activity ->
iron ion transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane AZF1, CIN5, INO4, MAC1, NRG1, PHD1, RCS1, ROX1, SFL1, SOK2, YAP6
YOR153W PDR5 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
ATPase activity, multidrug transporter activity, P-P-bond-hydrolysis-driven transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances plasma membrane ->
plasma membrane YAP6
|YNL014W| HEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity, ATPase activity ->
translation regulator activity, ATPase activity cytosolic ribosome (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex RAP1, SKN7
YNR045W PET494 protein biosynthesis ->
biosynthesis, protein metabolism translation regulator activity ->
translation regulator activity mitochondrial inner membrane ->
cytoplasm, inner membrane
Main: transport (0.60) ATPase activity (0.60) plasma membrane (0.60) YAP6 (0.50)
Score: 0.40 0.40 0.40 0.167
P-value: 1.010E-02 (response to drug) 2.618E-03 (xenobiotic-transporting ATPase activity) 3.190E-02 (plasma membrane) 2.349E-01 (YAP6)

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_phosphate_transport_orfnum2SD_n8(1) => SimExpr(YGR281W) OR SimExpr(other) : 6 2

EXPR: (0.213) m_phosphate_transport_orfnum2SD_n8 (P < 0.002) m_other_morphogenetic_activities_orfnum2SD_n8 (P < 0.002)

ORF SYMBOL P F C TF
YMR142C RPL13B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic large ribosomal subunit (sensu Eukarya) FHL1, GAT3, RAP1, RGM1, YAP5
YFR045W NO SYMBOL FKH1, PHO4, RIM101, UGA3, USV1
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane
|YJR017C| ESS1 mRNA processing, negative regulation of phosphorylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, phosphorus metabolism, regulation of metabolism peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity nucleus ->
nucleus
YGL186C TPN1 vitamin/cofactor transport ->
transport vitamin/cofactor transporter activity ->
vitamin/cofactor transporter activity plasma membrane ->
plasma membrane BAS1, SIG1, SKO1
|YIL052C| RPL34B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic large ribosomal subunit (sensu Eukarya) RME1
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
YGL098W USE1 RCS1
Main: biosynthesis (0.33) structural constituent of ribosome (0.33) cytosolic large ribosomal subunit (sensu Eukarya) (0.33) RCS1 (0.17)
Score: 0.20 0.07 0.20 0.000
P-value: 2.843E+00 (protein biosynthesis) 5.091E-01 (structural constituent of ribosome) 1.972E-01 (cytosolic large ribosomal subunit (sensu Eukarya)) 9.143E-01 (RIM101)

m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) AND m_glycolysis_and_gluconeogenesis_orfnum2SD_n14(1) => SimExpr(YGR281W) OR SimExpr(other) : 6 2

m_drug_transporters_orfnum2SD_n7(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) => SimExpr(YGR281W) OR SimExpr(other) : 5 2

m_anion_transporters_orfnum2SD_n15(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n14.scn(1) => SimExpr(YGR281W) OR SimExpr(other) : 6 2

EXPR: (0.207) m_anion_transporters_orfnum2SD_n15 (P < 0.002) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n14.scn (P < 0.000)

m_ion_transporters_orfnum2SD_n3(1) AND m_abc_transporters_orfnum2SD_n5(1) => SimExpr(YGR281W) OR SimExpr(other) : 5 2

EXPR: (0.196) m_abc_transporters_orfnum2SD_n5 (P < 0.012) m_ion_transporters_orfnum2SD_n3 (P < 0.000)

ORF SYMBOL P F C TF
|YGL114W| NO SYMBOL FKH2, MCM1, NDD1, YAP1
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus transporter activity ->
transporter activity plasma membrane ->
plasma membrane
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
YGR086C PIL1 ASH1, SWI5
|YDR307W| NO SYMBOL GRF10(Pho2), NDD1, YAP1
YNL003C PET8 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane MATa1
YMR319C FET4 low affinity iron ion transport, intracellular copper ion transport ->
transport transporter activity ->
transporter activity integral to plasma membrane ->
integral to membrane, plasma membrane AZF1, CIN5, INO4, MAC1, NRG1, PHD1, RCS1, ROX1, SFL1, SOK2, YAP6
Main: transport (0.75) transporter activity (0.75) plasma membrane (0.67) NDD1 YAP1 (0.40)
Score: 0.50 0.50 0.33 0.100
P-value: 9.339E-01 (transport) 1.153E-01 (transporter activity) 3.520E-01 (plasma membrane) 1.888E-01 (YAP1)

m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YGR281W) OR SimExpr(other) : 7 3

m_lipid_and_fatty-acid_binding_orfnum2SD_n13(1) AND m_glyoxylate_cycle_orfnum2SD_n11(1) => SimExpr(YNL231C) OR SimExpr(other) : 6 2

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND CSRE(1) AND SCB(1) => SimExpr(YPL087W) OR SimExpr(other) : 5 2

EXPR: (0.212) CSRE (P < 0.001) m_other_pheromone_response_activities_orfnum2SD_n8 (P < 0.004) SCB (P < 0.000)

ORF SYMBOL P F C TF
|YDL049C| KNH1 beta-1\,6 glucan biosynthesis ->
biosynthesis, carbohydrate metabolism extracellular, cell wall (sensu Fungi) ->
extracellular, cell wall FKH1, INO2, INO4, SKN7
|YPR145W| ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YPL087W YDC1 ceramide metabolism, response to heat ->
lipid metabolism, response to abiotic stimulus ceramidase activity ->
ceramidase activity endoplasmic reticulum ->
cytoplasm
YMR196W NO SYMBOL
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YNR001C CIT1 tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis citrate (SI)-synthase activity ->
citrate (SI)-synthase activity mitochondrial matrix, mitochondrion ->
cytoplasm RGM1
Main: biosynthesis (0.83) electron transporter activity (0.20) cytoplasm (0.60) MET4 (0.40)
Score: 0.73 0.00 0.30 0.100
P-value: 3.977E-03 (glutamate biosynthesis) 1.628E+00 (enzyme activity) 1.978E-01 (mitochondrial matrix) 8.354E-02 (MET4)

m_fermentation_orfnum2SD_n3(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n18(1) => SimExpr(YOL101C) OR SimExpr(other) : 5 2

m_tricarboxylic-acid_pathway_orfnum2SD_n3(1) AND m_amino-acid_transporters_orfnum2SD_n11(1) => SimExpr(YLR168C) OR SimExpr(other) : 6 1

EXPR: (0.190) m_tricarboxylic-acid_pathway_orfnum2SD_n3 (P < 0.006) m_amino-acid_transporters_orfnum2SD_n11 (P < 0.001)

ORF SYMBOL P F C TF
YMR272C SCS7 fatty acid metabolism ->
fatty acid metabolism oxidoreductase activity ->
oxidoreductase activity endoplasmic reticulum ->
endoplasmic reticulum IXR1, SUM1
YIL117C PRM5 conjugation with cellular fusion ->
conjugation with cellular fusion integral to membrane ->
integral to membrane
|YDL240W| LRG1 small GTPase mediated signal transduction, cell wall biosynthesis (sensu Fungi) ->
small GTPase mediated signal transduction, cell wall biosynthesis (sensu Fungi) Rho GTPase activator activity ->
Rho GTPase activator activity FKH1
YGR281W YOR1 transport, response to drug ->
transport, response to drug xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane
YLR168C NO SYMBOL HAP4
YPL260W NO SYMBOL SUM1
YPR157W NO SYMBOL
Main: conjugation with cellular fusion (0.25) Rho GTPase activator activity (0.33) endoplasmic reticulum (0.33) SUM1 (0.50)
Score: 0.00 0.00 0.00 0.167
P-value: 5.723E+00 (cell growth and/or maintenance) 2.849E+00 (enzyme activity) 2.010E+00 (membrane) 2.523E-02 (SUM1)

m_organization_of_chromosome_structure_orfnum2SD_n17(1) AND m_amino-acid_biosynthesis_orfnum2SD_n9(1) => SimExpr(YJL021C) OR SimExpr(other) : 5 1

ALPHA1(1) AND MCB(1) => SimExpr(YNL077W) OR SimExpr(other) : 23 9

m_metabolism_of_energy_reserves_orfnum2SD_n27(1) AND m_amino-acid_transport_orfnum2SD_n14(1) => SimExpr(YGR180C) OR SimExpr(other) : 5 2

m_LFTE17(1) AND m_purine_and_pyrimidine_transporters_orfnum2SD_n10(1) => SimExpr(YNL178W) OR SimExpr(other) : 5 1

ndt80(MSE)(1) AND m_metal_ion_transporters_orfnum2SD_n26(1) => SimExpr(YFR012W) : 5

m_pentose-phosphate_pathway_orfnum2SD_n21(1) AND m_glycolysis_and_gluconeogenesis_orfnum2SD_n14(1) => SimExpr(YMR315W) OR SimExpr(other) : 5 2

REB1(1) AND m_metal_ion_transporters_orfnum2SD_n6(1) => SimExpr(YNL111C) OR SimExpr(other) : 5 2

EXPR: (0.189) REB1 (P < 0.009) m_metal_ion_transporters_orfnum2SD_n6 (P < 0.001)

ORF SYMBOL P F C TF
|YLR212C| TUB4 microtubule nucleation, mitotic spindle assembly (sensu Saccharomyces) ->
cell organization and biogenesis, cell proliferation, cell cycle structural constituent of cytoskeleton ->
structural constituent of cytoskeleton inner plaque of spindle pole body, outer plaque of spindle pole body ->
cytoplasm
YOR025W HST3 chromatin silencing at telomere, short-chain fatty acid metabolism ->
cell organization and biogenesis, lipid metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription, organic acid metabolism DNA binding ->
DNA binding nucleus ->
nucleus IXR1, NDD1
YKR011C NO SYMBOL SWI4, SWI6
YML129C COX14 cytochrome c oxidase biogenesis, aerobic respiration ->
protein metabolism, energy pathways mitochondrial membrane, integral to membrane ->
cytoplasm, integral to membrane DOT6, MSS11, REB1
|YOR152C| NO SYMBOL HIR2
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YOR187W TUF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity mitochondrial matrix, mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex HAP4, REB1
Main: cell organization and biogenesis (0.40) DNA binding (0.25) cytoplasm (0.60) REB1 (0.50)
Score: 0.40 0.00 0.30 0.200
P-value: 3.627E-01 (lipid metabolism) 1.380E+00 (nucleic acid binding) 1.397E+00 (mitochondrion) 2.371E-02 (REB1)

m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND m_other_proteolytic_degradation_orfnum2SD_n7(1) => SimExpr(YNL111C) OR SimExpr(other) : 5 2

EXPR: (0.195) m_other_proteolytic_degradation_orfnum2SD_n7 (P < 0.009) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.000)

ORF SYMBOL P F C TF
YNR067C DSE4 cytokinesis\, completion of separation ->
cell proliferation glucan 1\,3-beta-glucosidase activity ->
glucan 1\,3-beta-glucosidase activity septum, extracellular ->
septum, extracellular YAP6
YKL077W NO SYMBOL CHA4, GCR1, HAP3, HIR1, IXR1, REB1, STP1
|YOL014W| NO SYMBOL
|YLR460C| NO SYMBOL CIN5, HAL9, YAP1
YGR194C XKS1 xylulose catabolism ->
alcohol metabolism, carbohydrate catabolism, catabolism, carbohydrate metabolism xylulokinase activity ->
xylulokinase activity HSF1
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
microsome ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall (sensu Fungi) RLM1, SMP1, STE12, SWI4
Main: alcohol metabolism (0.50) structural constituent of cell wall (0.25) septum (0.33) REB1 (0.33)
Score: 0.17 0.00 0.00 0.067
P-value: 2.275E-01 (alcohol metabolism) 2.849E+00 (enzyme activity) 3.000E+00 (cell) 5.628E-01 (REB1)

m_g-proteins_orfnum2SD_n13(1) AND REB1(1) => SimExpr(YNL111C) OR SimExpr(other) : 8 1

m_metabolism_of_energy_reserves_orfnum2SD_n8(1) AND m_g-proteins_orfnum2SD_n13(1) => SimExpr(YNL111C) OR SimExpr(other) : 5 2

EXPR: (0.222) m_metabolism_of_energy_reserves_orfnum2SD_n8 (P < 0.030) m_g-proteins_orfnum2SD_n13 (P < 0.010)

m_other_nucleotide-metabolism_activities_orfnum2SD_n17(1) AND m_anion_transporters_orfnum2SD_n10(1) => SimExpr(YNL111C) OR SimExpr(other) : 6 2

m_other_proteolytic_degradation_orfnum2SD_n7(1) AND REB1(1) => SimExpr(YNL111C) OR SimExpr(other) : 5 1

EXPR: (0.187) REB1 (P < 0.015) m_other_proteolytic_degradation_orfnum2SD_n7 (P < 0.007)

ORF SYMBOL P F C TF
YMR149W SWP1 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity ->
transferase activity\, transferring hexosyl groups oligosaccharyl transferase complex ->
cytoplasm, endomembrane system
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
|YGL248W| PDE1 cAMP-mediated signaling ->
signal transduction cAMP-specific phosphodiesterase activity ->
phosphoric ester hydrolase activity MSN2, MSN4
YNL185C MRPL19 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex
YDR427W RPN9 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome regulatory particle (sensu Eukarya), proteasome regulatory particle\, lid subcomplex (sensu Eukarya) ->
cytoplasm, nucleus ARG81, IXR1
YKR028W SAP190 G1/S transition of mitotic cell cycle ->
cell proliferation protein serine/threonine phosphatase activity ->
phosphoric ester hydrolase activity cytoplasm ->
cytoplasm PHO4, SMP1
Main: biosynthesis (0.50) phosphoric ester hydrolase activity (0.33) cytoplasm (0.80) GCR2 (0.25)
Score: 0.33 0.07 0.60 0.000
P-value: 1.059E+00 (biosynthesis) 9.527E-02 (phosphoric ester hydrolase activity) 3.910E-01 (endoplasmic reticulum) 3.669E-01 (MSN2)

MCB(1) AND m_nutritional_response_pathway_orfnum2SD_n7(1) => SimExpr(YGL163C) OR SimExpr(other) : 6 2

m_anion_transporters_orfnum2SD_n20(1) AND m_rRSE10(1) => SimExpr(YNL052W) OR SimExpr(other) : 5 2

m_MERE4(1) AND m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5(1) => SimExpr(YNL052W) OR SimExpr(other) : 6 3

EXPR: (0.206) m_organization_of_intracellular_transport_vesicles_orfnum2SD_n5 (P < 0.003) m_MERE4 (P < 0.007)

m_MERE4(1) AND m_phosphate_transport_orfnum2SD_n18(1) AND m_nitrogen_and_sulphur_utilization_orfnum2SD_n4(1) => SimExpr(YNL052W) OR SimExpr(other) : 6 3

EXPR: (0.224) m_nitrogen_and_sulphur_utilization_orfnum2SD_n4 (P < 0.004) m_phosphate_transport_orfnum2SD_n18 (P < 0.001) m_MERE4 (P < 0.019)

ORF SYMBOL P F C TF
YHR117W TOM71 protein transporter activity ->
protein transporter activity mitochondrial outer membrane ->
cytoplasm, outer membrane FKH1
|YNR062C| NO SYMBOL MCM1
YNL241C ZWF1 pentose-phosphate shunt ->
alcohol catabolism, carbohydrate metabolism, coenzyme metabolism, monosaccharide metabolism, water-soluble vitamin metabolism, carbohydrate catabolism, energy derivation by oxidation of organic compounds glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
|YNR018W| NO SYMBOL ACE2, FZF1, IME4, MBP1, NDD1, RAP1, SFP1, SKN7, SWI4, SWI5, YJL206C
YNL052W COX5A aerobic respiration ->
energy derivation by oxidation of organic compounds cytochrome c oxidase activity ->
cytochrome c oxidase activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
YOR032C HMS1 pseudohyphal growth ->
cellular morphogenesis transcription factor activity ->
transcription factor activity CUP9, HAL9, INO4, NRG1, RAP1, SFP1, YAP6
|YOL068C| HST1 transcriptional gene silencing ->
gene silencing, transcription NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity ->
NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity histone deacetylase complex, nucleus ->
nucleus ABF1
YPL219W PCL8 regulation of glycogen catabolism, regulation of glycogen biosynthesis ->
carbohydrate catabolism, carbohydrate biosynthesis, regulation of catabolism, regulation of biosynthesis, polysaccharide metabolism, energy derivation by oxidation of organic compounds cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cellular morphogenesis, sporulation (sensu Fungi), cell surface receptor linked signal transduction, intracellular signaling cascade RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
plasma membrane ACE2, SKN7
Main: energy derivation by oxidation of organic compounds (0.50) protein transporter activity (0.14) cytoplasm (0.50) ACE2 SKN7 SFP1 (0.38)
Score: 0.27 0.00 0.20 0.179
P-value: 1.374E-01 (energy pathways) 8.927E-01 (oxidoreductase activity) 5.779E-01 (mitochondrial membrane) 5.153E-03 (ACE2)

m_MERE4(1) AND m_other_energy_generation_activities_orfnum2SD_n22(1) => SimExpr(YNL052W) OR SimExpr(other) : 9 4

EXPR: (0.216) m_other_energy_generation_activities_orfnum2SD_n22 (P < 0.002) m_MERE4 (P < 0.003)

ORF SYMBOL P F C TF
YKR042W UTH1 mitochondrion organization and biogenesis ->
cell organization and biogenesis cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, membrane ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YNL052W COX5A aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors\, oxygen as acceptor, transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, membrane HAP4
YJL145W SFH5 phospholipid transport ->
transport phosphatidylinositol transporter activity ->
phosphatidylinositol binding, transporter activity DIG1, HAP3, NRG1, RCS1, RFX1
|YDR384C| ATO3 transport, nitrogen utilization ->
transport, nitrogen metabolism transporter activity ->
transporter activity membrane ->
membrane ABF1, FHL1, INO4
YDL181W INH1 ATP synthesis coupled proton transport ->
transport proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, membrane HAP4
YOR136W IDH2 tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis isocitrate dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrial matrix, mitochondrion ->
cytoplasm MET4
YHR083W NO SYMBOL DIG1, STE12
|YJL079C| PRY1 nuclear membrane, endoplasmic reticulum ->
nucleus, cytoplasm, membrane NDD1, PHD1, RAP1
|YLR377C| FBP1 gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, biosynthesis, energy pathways fructose-bisphosphatase activity ->
phosphoric ester hydrolase activity cytosol ->
cytoplasm
YOR307C SLY41 ER to Golgi transport ->
transport, vesicle-mediated transport PDR1
|YJL082W| IML2
YDL137W ARF2 ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport ARF small monomeric GTPase activity ->
guanyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides Golgi vesicle, cytosol ->
cytoplasm, Golgi apparatus MSS11, REB1, RGT1, SIG1, SKN7, SOK2
Main: transport (0.50) transporter activity (0.43) cytoplasm (0.89) SKN7 NDD1 (0.27)
Score: 0.33 0.19 0.89 0.164
P-value: 5.399E-02 (energy pathways) 3.240E-01 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 2.711E-01 (mitochondrial membrane) 1.937E-01 (NDD1)

m_phosphate_transport_orfnum2SD_n18(1) AND m_anion_transporters_orfnum2SD_n10(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YNL052W) OR SimExpr(other) : 5 1

EXPR: (0.190) m_phosphate_transport_orfnum2SD_n18 (P < 0.000) m_anion_transporters_orfnum2SD_n10 (P < 0.001) m_anion_transporters_orfnum2SD_n20 (P < 0.006)

ORF SYMBOL P F C TF
YNL241C ZWF1 pentose-phosphate shunt ->
alcohol catabolism, carbohydrate metabolism, coenzyme metabolism, monosaccharide metabolism, water-soluble vitamin metabolism, carbohydrate catabolism, energy derivation by oxidation of organic compounds glucose-6-phosphate 1-dehydrogenase activity ->
glucose-6-phosphate 1-dehydrogenase activity cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YNL052W COX5A aerobic respiration ->
energy derivation by oxidation of organic compounds transporter activity ->
transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, membrane HAP4
|YDR384C| ATO3 transport, nitrogen utilization ->
transport, nitrogen utilization transporter activity ->
transporter activity membrane ->
membrane ABF1, FHL1, INO4
YGR035C NO SYMBOL CIN5, MET4, SMP1, YAP6
YNL098C RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cellular morphogenesis, sporulation (sensu Fungi), cell surface receptor linked signal transduction, intracellular signaling cascade RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity plasma membrane ->
membrane ACE2, SKN7
YMR086W NO SYMBOL FKH1
Main: energy derivation by oxidation of organic compounds (0.50) transporter activity (0.50) membrane (0.75) ACE2 SKN7 (0.33)
Score: 0.17 0.17 0.67 0.067
P-value: 2.492E-01 (energy pathways) 5.944E-01 (transporter activity) 8.261E-01 (membrane) 5.930E-02 (ACE2)

m_g-proteins_orfnum2SD_n11(1) AND HAP234(1) => SimExpr(YNL052W) OR SimExpr(other) : 5 2

EXPR: (0.219) m_g-proteins_orfnum2SD_n11 (P < 0.005) HAP234 (P < 0.211)

m_MERE4(1) AND HAP234(1) => SimExpr(YNL052W) OR SimExpr(other) : 7 1

m_phosphate_transport_orfnum2SD_n18(1) AND HAP234(1) => SimExpr(YNL052W) OR SimExpr(other) : 6 1

m_anion_transporters_orfnum2SD_n17(1) AND HAP234(1) => SimExpr(YNL052W) OR SimExpr(other) : 5 1

m_phosphate_transport_orfnum2SD_n8(1) AND m_other_intracellular-transport_activities_orfnum2SD_n9(1) => SimExpr(YNL052W) OR SimExpr(other) : 7 3

EXPR: (0.235) m_phosphate_transport_orfnum2SD_n8 (P < 0.008) m_other_intracellular-transport_activities_orfnum2SD_n9 (P < 0.024)

ORF SYMBOL P F C TF
YNL052W COX5A aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors, primary active transporter activity, cation transporter activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP4
|YLR394W| CST9 DNA replication and chromosome cycle ->
cell proliferation DNA binding ->
DNA binding SMP1
|YMR318C| ADH6 aldehyde metabolism, alcohol metabolism ->
aldehyde metabolism, alcohol metabolism alcohol dehydrogenase (NADP+) activity ->
oxidoreductase activity\, acting on CH-OH group of donors soluble fraction ->
soluble fraction
YKL126W YPK1 protein amino acid phosphorylation, sphingolipid metabolism, endocytosis ->
phosphorus metabolism, lipid metabolism, transport, protein metabolism protein serine/threonine kinase activity ->
transferase activity\, transferring phosphorus-containing groups plasma membrane, cytosol, bud neck ->
plasma membrane, cytoplasm, site of polarized growth (sensu Fungi)
YPR138C MEP3 ammonium transport ->
transport ammonium transporter activity ->
cation transporter activity plasma membrane ->
plasma membrane
YNR017W MAS6 mitochondrial translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity mitochondrial inner membrane pre-sequence translocase complex, mitochondrion ->
cytoplasm, inner membrane HSF1, INO2, INO4, REB1, YJL206C
YHR063C PAN5 pantothenate biosynthesis ->
biosynthesis, coenzymes and prosthetic group metabolism gluconate 5-dehydrogenase activity ->
oxidoreductase activity\, acting on CH-OH group of donors MBP1, SWI4
|YOR342C| NO SYMBOL RAP1
YNL008C ASI3 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism ubiquitin-protein ligase activity ->
ligase activity\, forming carbon-nitrogen bonds endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YGL098W USE1 RCS1
Main: transport (0.38) oxidoreductase activity\, acting on CH-OH group of donors (0.25) cytoplasm (0.67) REB1 (0.29)
Score: 0.18 0.07 0.47 0.048
P-value: 2.689E+00 (transport) 1.954E-01 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor) 6.117E-01 (membrane) 5.864E-01 (REB1)

m_allantoin_and_allantoate_transporters_orfnum2SD_n12(1) AND m_other_signal-transduction_activities_orfnum2SD_n13(1) => SimExpr(YDL028C) OR SimExpr(other) : 5 2

EXPR: (0.210) m_allantoin_and_allantoate_transporters_orfnum2SD_n12 (P < 0.001) m_other_signal-transduction_activities_orfnum2SD_n13 (P < 0.000)

ORF SYMBOL P F C TF
YJR150C DAN1 sterol transport ->
transport cell wall (sensu Fungi) ->
cell wall PHO4
YDR153C ENT5 Golgi to endosome transport ->
cell organization and biogenesis, transport, vesicle-mediated transport clathrin binding ->
clathrin binding cytoplasm, clathrin vesicle coat ->
cytoplasm, membrane coat
|YFL039C| ACT1 cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter ->
transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex ->
cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex DIG1, ROX1, STE12
|YPL231W| FAS2 fatty acid biosynthesis, protein-cofactor linkage ->
protein metabolism, biosynthesis, lipid metabolism, organic acid metabolism 3-oxoacyl-[acyl-carrier protein] synthase activity, 3-oxoacyl-[acyl-carrier protein] reductase activity, holo-[acyl-carrier protein] synthase activity ->
transferase activity\, transferring acyl groups, oxidoreductase activity\, acting on CH-OH group of donors, transferase activity\, transferring phosphorus-containing groups fatty-acid synthase complex ->
cytoplasm INO2, INO4
YDL028C MPS1 mitotic spindle checkpoint, spindle pole body duplication (sensu Saccharomyces) ->
cell organization and biogenesis, cell cycle protein threonine/tyrosine kinase activity ->
transferase activity\, transferring phosphorus-containing groups spindle pole body, condensed nuclear chromosome kinetochore ->
cytoplasm, chromosome\, pericentric region, condensed chromosome, chromosome, nucleus SUM1
YLR278C NO SYMBOL INO4, MSN1
YJR138W IML1 ABF1, DOT6, GCR2, MET31, REB1
Main: cell organization and biogenesis (0.60) transferase activity\, transferring phosphorus-containing groups (0.50) cytoplasm (0.80) INO4 (0.33)
Score: 0.60 0.17 0.60 0.067
P-value: 1.242E-01 (M-phase specific microtubule process) 5.648E-01 (transferase activity\, transferring phosphorus-containing groups) 4.048E-01 (cytoskeleton) 1.973E-01 (INO4)

m_drug_transporters_orfnum2SD_n10(1) AND m_nitrogen_and_sulphur_transport_orfnum2SD_n9(1) => SimExpr(YMR220W) OR SimExpr(other) : 7 2

m_drug_transporters_orfnum2SD_n10(1) AND m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6(1) => SimExpr(YMR220W) OR SimExpr(other) : 6 1

SFF'(1) AND m_drug_transporters_orfnum2SD_n10(1) AND m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6(1) => SimExpr(YMR220W) : 5

EXPR: (0.149) m_drug_transporters_orfnum2SD_n10 (P < 0.000) SFF' (P < 0.000) m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6 (P < 0.001)

ORF SYMBOL P F C TF
YMR220W ERG8 ergosterol biosynthesis, isoprenoid biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism phosphomevalonate kinase activity ->
phosphomevalonate kinase activity cytosol ->
cytoplasm
YMR024W MRPL3 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex
YML116W ATR1 multidrug transport ->
transport, response to abiotic stimulus multidrug efflux pump activity ->
multidrug efflux pump activity plasma membrane ->
plasma membrane CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YNL208W NO SYMBOL INO2
YKL164C PIR1 intracellular protein transport, cell wall organization and biogenesis ->
cell organization and biogenesis, transport structural constituent of cell wall ->
structural constituent of cell wall cell wall ->
cell wall BAS1, MCM1, PHD1, SMP1, SWI5
Main: biosynthesis (0.50) structural constituent of cell wall (0.25) cytoplasm (0.50) PHD1 (0.67)
Score: 0.33 0.00 0.17 0.333
P-value: 2.177E+00 (transport) 2.710E-01 (structural molecule activity) 4.460E+00 (cytoplasm) 1.067E-01 (PHD1)

ALPHA1(1) AND SFF(1) AND m_g-proteins_orfnum2SD_n11(1) AND CCA(1) => SimExpr(YGL187C) OR SimExpr(other) : 5 2

EXPR: (0.209) m_g-proteins_orfnum2SD_n11 (P < 0.005) SFF (P < 0.002) CCA (P < 0.000) ALPHA1 (P < 0.001)

ORF SYMBOL P F C TF
YLR328W NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity CIN5, MSN1, ROX1
YGL187C COX4 aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
cytochrome c oxidase activity respiratory chain complex IV (sensu Eukarya) ->
intracellular, inner membrane HAP2, HAP3, HAP4, HAP5
|YDR440W| DOT1 histone methylation, chromatin silencing at telomere, regulation of meiosis ->
cell organization and biogenesis, cell cycle, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription protein-lysine N-methyltransferase activity ->
protein-lysine N-methyltransferase activity nucleus ->
intracellular CRZ1, DOT6, PHO4, RTG1
YGL191W COX13 aerobic respiration ->
energy pathways cytochrome c oxidase activity, enzyme regulator activity ->
cytochrome c oxidase activity, enzyme regulator activity respiratory chain complex IV (sensu Eukarya) ->
intracellular, inner membrane DOT6, HAP4, REB1, RGT1
|YIL118W| RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
signal transduction, cell organization and biogenesis, transport Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YKL034W TUL1 protein transport ->
transport ligase activity ->
ligase activity intracellular ->
intracellular
YOL082W CVT19 protein-vacuolar targeting ->
cell organization and biogenesis, protein metabolism, transport protein binding ->
protein binding vacuole, peripheral membrane protein of membrane fraction, cytoplasm ->
intracellular, membrane fraction GTS1, MCM1, RAP1, STE12
Main: cell organization and biogenesis (0.43) cytochrome c oxidase activity (0.29) intracellular (1.00) CIN5 DOT6 HAP4 (0.33)
Score: 0.29 0.05 1.00 0.200
P-value: 6.161E-02 (aerobic respiration) 4.138E-03 (cytochrome c oxidase activity) 3.007E-03 (respiratory chain complex IV (sensu Eukarya)) 8.621E-02 (HAP4)

ALPHA1(1) AND m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_g-proteins_orfnum2SD_n11(1) AND CCA(1) => SimExpr(YGL187C) OR SimExpr(other) : 5 1

EXPR: (0.184) m_g-proteins_orfnum2SD_n11 (P < 0.000) CCA (P < 0.000) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YLR328W NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity CIN5, MSN1, ROX1
YGL187C COX4 aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
cytochrome c oxidase activity respiratory chain complex IV (sensu Eukarya) ->
intracellular, inner membrane HAP2, HAP3, HAP4, HAP5
|YDR440W| DOT1 histone methylation, chromatin silencing at telomere, regulation of meiosis ->
cell organization and biogenesis, cell cycle, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription protein-lysine N-methyltransferase activity ->
protein-lysine N-methyltransferase activity nucleus ->
intracellular CRZ1, DOT6, PHO4, RTG1
YOL065C INP54 exocytosis ->
transport inositol-1\,4\,5-trisphosphate 5-phosphatase activity ->
inositol-1\,4\,5-trisphosphate 5-phosphatase activity endoplasmic reticulum ->
intracellular AZF1, SIP4
YKL034W TUL1 protein transport ->
transport ligase activity ->
ligase activity intracellular ->
intracellular
YOL082W CVT19 protein-vacuolar targeting ->
cell organization and biogenesis, protein metabolism, transport protein binding ->
protein binding vacuole, peripheral membrane protein of membrane fraction, cytoplasm ->
intracellular, membrane fraction GTS1, MCM1, RAP1, STE12
Main: transport (0.50) nicotinamide-nucleotide adenylyltransferase activity (0.17) intracellular (1.00) HAP3 (0.20)
Score: 0.27 0.00 1.00 0.000
P-value: 4.813E-01 (protein transport) 5.126E-01 (enzyme activity) 3.918E+00 (cytoplasm) 4.341E-01 (MSN1)

m_nitrogen_and_sulphur_metabolism_orfnum2SD_n16(1) AND m_other_energy_generation_activities_orfnum2SD_n11(1) => SimExpr(YGL187C) OR SimExpr(other) : 6 2

EXPR: (0.217) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n16 (P < 0.000) m_other_energy_generation_activities_orfnum2SD_n11 (P < 0.011)

ORF SYMBOL P F C TF
YGL187C COX4 aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
cytochrome c oxidase activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP2, HAP3, HAP4, HAP5
YNR074C NO SYMBOL GTS1
YDR421W ARO80 positive regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ARO80, GAT1, YFL044C
YML129C COX14 cytochrome c oxidase biogenesis, aerobic respiration ->
protein metabolism, energy pathways mitochondrial membrane, integral to membrane ->
cytoplasm, integral to membrane DOT6, MSS11, REB1
|YDR044W| HEM13 heme biosynthesis ->
pigment metabolism, coenzymes and prosthetic group biosynthesis, coenzymes and prosthetic group metabolism, biosynthesis, heterocycle metabolism coproporphyrinogen oxidase activity ->
coproporphyrinogen oxidase activity mitochondrial inner membrane ->
cytoplasm, inner membrane
YOL148C SPT20 chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription cofactor activity ->
transcription cofactor activity SAGA complex ->
nucleus GRF10(Pho2), MATa1, MIG1, PHO4
|YNL101W| AVT4 neutral amino acid transport ->
transport neutral amino acid transporter activity ->
neutral amino acid transporter activity vacuole ->
cytoplasm HAP3, INO4, IXR1, PHD1, RAP1
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.43) transcription cofactor activity (0.17) cytoplasm (0.67) HAP3 (0.33)
Score: 0.33 0.00 0.47 0.067
P-value: 7.126E-02 (aerobic respiration) 7.298E-01 (oxidoreductase activity) 6.372E-02 (mitochondrial membrane) 1.367E-01 (HAP3)

ALPHA1(1) AND m_nitrogen_and_sulphur_metabolism_orfnum2SD_n16(1) AND m_other_energy_generation_activities_orfnum2SD_n11(1) => SimExpr(YGL187C) : 5

EXPR: (0.154) m_nitrogen_and_sulphur_metabolism_orfnum2SD_n16 (P < 0.000) m_other_energy_generation_activities_orfnum2SD_n11 (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YGL187C COX4 aerobic respiration ->
energy pathways cytochrome c oxidase activity ->
cytochrome c oxidase activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, inner membrane HAP2, HAP3, HAP4, HAP5
YDR421W ARO80 positive regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ARO80, GAT1, YFL044C
YML129C COX14 cytochrome c oxidase biogenesis, aerobic respiration ->
protein metabolism, energy pathways mitochondrial membrane, integral to membrane ->
cytoplasm, integral to membrane DOT6, MSS11, REB1
YOL148C SPT20 chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription cofactor activity ->
transcription cofactor activity SAGA complex ->
nucleus GRF10(Pho2), MATa1, MIG1, PHO4
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.60) transcription cofactor activity (0.25) cytoplasm (0.50) HAP3 (0.25)
Score: 0.60 0.00 0.33 0.000
P-value: 2.052E-02 (aerobic respiration) 2.445E-01 (transcription regulator activity) 2.059E-01 (mitochondrial membrane) 5.044E-01 (GAT1)

m_amino-acid_degradation_orfnum2SD_n8(1) AND m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) => SimExpr(YGL108C) : 5

EXPR: (0.178) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.001) m_allantoin_and_allantoate_transporters_orfnum2SD_n13 (P < 0.001) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.002)

ORF SYMBOL P F C TF
YGL108C NO SYMBOL DAL82, MAL13, SWI5, YAP5
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YPR138C MEP3 ammonium transport ->
transport ammonium transporter activity ->
ammonium transporter activity plasma membrane ->
plasma membrane
YHR195W NVJ1 microautophagy ->
autophagy protein binding ->
protein binding nuclear membrane ->
nucleus, endomembrane system ACE2, MBP1, NRG1, SMP1
YOR264W DSE3 SWI5
Main: transport (0.67) ammonium transporter activity (0.33) endomembrane system (0.67) MAL13 SWI5 (0.50)
Score: 0.33 0.00 0.33 0.333
P-value: 1.633E+00 (transport) 3.212E-01 (transporter activity) 2.096E-01 (endomembrane system) 1.142E-02 (MAL13)

m_tricarboxylic-acid_pathway_orfnum2SD_n6(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) AND m_anion_transporters_orfnum2SD_n10(1) => SimExpr(YGL108C) : 5

EXPR: (0.187) m_tricarboxylic-acid_pathway_orfnum2SD_n6 (P < 0.002) m_allantoin_and_allantoate_transporters_orfnum2SD_n13 (P < 0.002) m_anion_transporters_orfnum2SD_n10 (P < 0.000)

ORF SYMBOL P F C TF
YKL085W MDH1 tricarboxylic acid cycle, malate metabolism ->
tricarboxylic acid cycle, malate metabolism L-malate dehydrogenase activity ->
L-malate dehydrogenase activity mitochondrial matrix ->
cytoplasm IME4, MTH1, RTG1, YJL206C
YGL108C NO SYMBOL DAL82, MAL13, SWI5, YAP5
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
SRP-dependent cotranslational membrane targeting\, translocation protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YHR195W NVJ1 microautophagy ->
microautophagy protein binding ->
protein binding nuclear membrane ->
nucleus, endomembrane system ACE2, MBP1, NRG1, SMP1
YOR264W DSE3 SWI5
Main: SRP-dependent cotranslational membrane targeting\, translocation (0.33) protein transporter activity (0.33) cytoplasm (0.67) MAL13 SWI5 (0.40)
Score: 0.00 0.00 0.67 0.200
P-value: 5.069E+00 (cell growth and/or maintenance) 2.000E+00 (molecular_function) 2.445E-01 (endomembrane system) 1.650E-02 (MAL13)

m_lipid_and_fatty-acid_binding_orfnum2SD_n13(1) AND SFF'(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) => SimExpr(YGL108C) : 6

EXPR: (0.185) SFF' (P < 0.000) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.000) m_lipid_and_fatty-acid_binding_orfnum2SD_n13 (P < 0.000)

ORF SYMBOL P F C TF
YPR022C NO SYMBOL
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
cell organization and biogenesis, phosphorus metabolism, signal transduction, protein metabolism protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YGL108C NO SYMBOL DAL82, MAL13, SWI5, YAP5
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YHR208W BAT1 branched chain family amino acid biosynthesis, amino acid catabolism ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis, catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity mitochondrial matrix ->
cytoplasm LEU3, PHO4
YLR168C NO SYMBOL HAP4
Main: cell organization and biogenesis (0.67) protein transporter activity (0.33) cytoplasm (1.00) MAL13 (0.40)
Score: 0.33 0.00 1.00 0.100
P-value: 4.228E+00 (protein metabolism) 9.703E-01 (transferase activity) 3.918E+00 (cytoplasm) 1.890E-02 (MAL13)

SFF(1) AND m_lipid_and_fatty-acid_binding_orfnum2SD_n13(1) AND m_amino-acid_degradation_orfnum2SD_n8(1) => SimExpr(YGL108C) : 5

EXPR: (0.172) SFF (P < 0.000) m_amino-acid_degradation_orfnum2SD_n8 (P < 0.000) m_lipid_and_fatty-acid_binding_orfnum2SD_n13 (P < 0.000)

ORF SYMBOL P F C TF
YPR022C NO SYMBOL
YJL164C TPK1 pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction ->
pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction protein serine/threonine kinase activity, cAMP-dependent protein kinase activity ->
protein serine/threonine kinase activity, cAMP-dependent protein kinase activity cytoplasm, cAMP-dependent protein kinase complex ->
cytoplasm, cAMP-dependent protein kinase complex DOT6, SFL1
YGL108C NO SYMBOL DAL82, MAL13, SWI5, YAP5
YHR208W BAT1 branched chain family amino acid biosynthesis, amino acid catabolism ->
branched chain family amino acid biosynthesis, amino acid catabolism branched-chain amino acid aminotransferase activity ->
branched-chain amino acid aminotransferase activity mitochondrial matrix ->
cytoplasm LEU3, PHO4
YLR168C NO SYMBOL HAP4
Main: pseudohyphal growth (0.50) branched-chain amino acid aminotransferase activity (0.50) cytoplasm (1.00) SFL1 (0.25)
Score: 0.00 0.00 1.00 0.000
P-value: 3.848E+00 (metabolism) 7.188E-01 (transferase activity) 4.460E+00 (cytoplasm) 4.736E-01 (DAL82)

m_cell_death_orfnum2SD_n16(1) AND m_lipid_transporters_orfnum2SD_n8(1) => SimExpr(YHR178W) OR SimExpr(other) : 5 1

EXPR: (0.217) m_cell_death_orfnum2SD_n16 (P < 0.001) m_lipid_transporters_orfnum2SD_n8 (P < 0.003)

m_RRSE3(1) AND m_g-proteins_orfnum2SD_n12(1) AND PAC(1) => SimExpr(YJR002W) OR SimExpr(other) : 18 7

EXPR: (0.239) m_g-proteins_orfnum2SD_n12 (P < 0.000) m_RRSE3 (P < 0.000) PAC (P < 0.026)

m_RRSE3(1) AND PAC(1) AND mRRPE(1) => SimExpr(YJR002W) OR SimExpr(other) : 30 9

PAC(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n18(1) => SimExpr(YJR002W) OR SimExpr(other) : 5 1

EXPR: (0.205) PAC (P < 0.017) m_allantoin_and_allantoate_transporters_orfnum2SD_n18 (P < 0.000)

ORF SYMBOL P F C TF
YNL141W AAH1 adenine catabolism ->
aromatic compound metabolism, catabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism adenine deaminase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds YFL044C
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex ABF1
YDR017C KCS1 vacuole organization and biogenesis, response to stress ->
cell organization and biogenesis, response to stress inositol/phosphatidylinositol kinase activity ->
transferase activity\, transferring phosphorus-containing groups
YJR002W MPP10 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
nucleolus, small nuclear ribonucleoprotein complex, nucleus, ribonucleoprotein complex
YHR169W DBP8 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus
|YGL255W| ZRT1 high-affinity zinc ion transport ->
transport high affinity zinc uptake transporter activity ->
cation transporter activity, metal ion transporter activity integral to plasma membrane ->
integral to plasma membrane GRF10(Pho2), ZAP1
Main: cell organization and biogenesis (0.67) RNA binding (0.40) nucleolus (0.75) ABF1 (0.33)
Score: 0.60 0.10 0.50 0.000
P-value: 9.857E-03 (rRNA processing) 5.408E-01 (RNA binding) 8.615E-03 (small nucleolar ribonucleoprotein complex) 1.823E-01 (ZAP1)

PAC(1) AND m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n8.scn(1) => SimExpr(YJR002W) OR SimExpr(other) : 7 1

EXPR: (0.220) m_regulation_of_lipid_fatty-acid_and_isoprenoid_biosynthesis_orfnum2SD_n8.scn (P < 0.000) PAC (P < 0.026)

ORF SYMBOL P F C TF
|YMR196W| NO SYMBOL
YIL122W POG1 re-entry into mitotic cell cycle after pheromone arrest ->
re-entry into mitotic cell cycle, conjugation with cellular fusion, response to pheromone specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YMR185W NO SYMBOL
YFL007W BLM3 membrane ->
membrane
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleus ->
nucleus STB1
YHR088W RPF1 processing of 27S pre-rRNA, ribosomal large subunit assembly and maintenance ->
rRNA processing, ribosomal subunit assembly rRNA primary transcript binding ->
rRNA primary transcript binding nucleolus ->
nucleus FKH1
YJR002W MPP10 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
rRNA modification, rRNA processing small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YGR162W TIF4631 translational initiation ->
translational initiation translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex HSF1
Main: rRNA processing (0.60) rRNA primary transcript binding (0.33) nucleus (0.67) RLM1 (0.25)
Score: 0.30 0.00 0.47 0.000
P-value: 2.363E-02 (rRNA processing) 1.647E+00 (nucleic acid binding) 2.848E-01 (nucleolus) 6.885E-01 (ASH1)

ALPHA1(1) AND m_RRSE3(1) AND PAC(1) => SimExpr(YJR002W) OR SimExpr(other) : 14 5

EXPR: (0.238) m_RRSE3 (P < 0.000) PAC (P < 0.034) ALPHA1 (P < 0.000)

ALPHA1(1) AND PAC(1) AND m_phosphate_transport_orfnum2SD_n18(1) => SimExpr(YJR002W) OR SimExpr(other) : 6 1

EXPR: (0.230) m_phosphate_transport_orfnum2SD_n18 (P < 0.000) PAC (P < 0.068) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YMR302C| PRP12 mitochondrial genome maintenance, rRNA processing ->
cytoplasm organization and biogenesis, RNA processing, transcription exonuclease activity ->
exonuclease activity mitochondrial inner membrane ->
intracellular, inner membrane
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YMR185W NO SYMBOL
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription nucleus ->
intracellular STB1
YIL118W RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
secretory pathway, intracellular signaling cascade, cytoplasm organization and biogenesis, vesicle-mediated transport Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YJR002W MPP10 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription\, DNA-dependent small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
intracellular
YNL163C RIA1 ribosome biogenesis ->
cytoplasm organization and biogenesis translation elongation factor activity ->
translation elongation factor activity cytoplasm ->
intracellular FHL1, RAP1, YAP5
Main: cytoplasm organization and biogenesis (1.00) translation elongation factor activity (0.33) intracellular (1.00) RTS2 (0.25)
Score: 1.00 0.00 1.00 0.000
P-value: 1.702E-03 (ribosome biogenesis) 2.070E+00 (nucleic acid binding) 4.624E+00 (nucleus) 8.743E-01 (RTS2)

ALPHA1(1) AND m_g-proteins_orfnum2SD_n11(1) AND PAC(1) => SimExpr(YHR196W) OR SimExpr(other) : 7 2

EXPR: (0.211) m_g-proteins_orfnum2SD_n11 (P < 0.000) PAC (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YNL207W RIO2 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleocytoplasmic transporter activity, protein kinase activity ->
nucleocytoplasmic transporter activity, protein kinase activity cytosol, nucleus ->
intracellular ABF1, MAL33
YGR251W NO SYMBOL MSN4, PHD1, SKN7
|YLR249W| YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
intracellular INO2, INO4
YHR196W UTP9 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
snoRNA binding small nucleolar ribonucleoprotein complex, nucleolus, nucleus ->
intracellular
YKR092C SRP40 nucleocytoplasmic transport ->
transport chaperone activity ->
chaperone activity nucleolus ->
intracellular CUP9, MET4, RAP1
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleus ->
intracellular STB1
YIL118W RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
signal transduction, cell organization and biogenesis, transport Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YPR137W RRP9 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription snoRNA binding ->
snoRNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
intracellular ABF1, HIR1, RCS1
|YJL105W| SET4 ASH1, CIN5, FKH1, MTH1, PHD1, SKN7
Main: cell organization and biogenesis (0.71) snoRNA binding (0.33) intracellular (1.00) SKN7 PHD1 (0.38)
Score: 0.52 0.07 1.00 0.143
P-value: 1.123E-03 (processing of 20S pre-rRNA) 1.033E-02 (snoRNA binding) 2.292E-02 (small nucleolar ribonucleoprotein complex) 4.175E-02 (PHD1)

ALPHA1(1) AND PAC(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YHR196W) OR SimExpr(other) : 5 1

ALPHA1(1) AND m_glyoxylate_cycle_orfnum2SD_n11(1) AND PAC(1) => SimExpr(YHR196W) OR SimExpr(other) : 5 2

EXPR: (0.234) PAC (P < 0.041) ALPHA1 (P < 0.000) m_glyoxylate_cycle_orfnum2SD_n11 (P < 0.000)

ORF SYMBOL P F C TF
YGR251W NO SYMBOL MSN4, PHD1, SKN7
|YLR249W| YEF3 translational elongation ->
translational elongation translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YHR196W UTP9 processing of 20S pre-rRNA ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter snoRNA binding ->
snoRNA binding small nucleolar ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
|YFL007W| BLM3 membrane ->
membrane
YKR092C SRP40 nucleocytoplasmic transport ->
nucleocytoplasmic transport chaperone activity ->
chaperone activity nucleolus ->
nucleus CUP9, MET4, RAP1
YJR002W MPP10 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YNL163C RIA1 ribosome biogenesis ->
ribosome biogenesis translation elongation factor activity ->
translation elongation factor activity cytoplasm ->
cytoplasm FHL1, RAP1, YAP5
Main: ribosome biogenesis (0.60) translation elongation factor activity (0.50) nucleus (0.50) RAP1 (0.50)
Score: 0.30 0.17 0.40 0.167
P-value: 3.198E-02 (processing of 20S pre-rRNA) 2.549E-03 (translation elongation factor activity) 1.350E-02 (small nucleolar ribonucleoprotein complex) 6.262E-01 (RAP1)

m_c-compound_and_carbohydrate_utilization_orfnum2SD_n31(1) AND m_anion_transporters_orfnum2SD_n20(1) => SimExpr(YGL062W) OR SimExpr(other) : 5 2

m_pentose-phosphate_pathway_orfnum2SD_n21(1) AND m_glycolysis_and_gluconeogenesis_orfnum2SD_n14(1) => SimExpr(YGL062W) OR SimExpr(other) : 5 2

SWI5(1) AND m_amino-acid_transport_orfnum2SD_n18(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YMR298W) OR SimExpr(other) : 6 2

EXPR: (0.218) SWI5 (P < 0.000) m_amino-acid_transport_orfnum2SD_n18 (P < 0.000) m_amino-acid_transport_orfnum2SD_n20 (P < 0.005)

ORF SYMBOL P F C TF
YOR348C PUT4 neutral amino acid transport ->
amine/polyamine transport, carboxylic acid transport amino acid permease activity, neutral amino acid transporter activity ->
amino acid permease activity, neutral amino acid transporter activity plasma membrane ->
plasma membrane SWI5
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosome biogenesis and assembly structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
|YFR022W| NO SYMBOL
YMR298W NO SYMBOL CIN5
|YOR088W| NO SYMBOL
YKR039W GAP1 amino acid transport ->
amine/polyamine transport, carboxylic acid transport general amino acid permease activity ->
amino acid permease activity integral to plasma membrane ->
integral to membrane, plasma membrane CIN5, YAP6
YOR062C NO SYMBOL GRF10(Pho2)
YOR187W TUF1 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity mitochondrial matrix, mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex HAP4, REB1
Main: amine/polyamine transport (0.50) amino acid permease activity (0.50) cytoplasm (0.50) CIN5 GRF10(Pho2) (0.33)
Score: 0.33 0.17 0.33 0.133
P-value: 1.870E-02 (amino acid transport) 1.272E-03 (amino acid permease activity) 8.101E-01 (plasma membrane) 5.955E-02 (GRF10(Pho2))

m_glyoxylate_cycle_orfnum2SD_n7(1) AND m_anion_transporters_orfnum2SD_n9(1) => SimExpr(YMR322C) OR SimExpr(other) : 5 2

EXPR: (0.233) m_anion_transporters_orfnum2SD_n9 (P < 0.004) m_glyoxylate_cycle_orfnum2SD_n7 (P < 0.001)

ORF SYMBOL P F C TF
YPL280W NO SYMBOL
YMR322C SNO4 protein binding ->
protein binding
YOR052C NO SYMBOL
YPL265W DIP5 amino acid transport ->
transport amino acid permease activity, amino acid transporter activity ->
amino acid permease activity, amino acid transporter activity plasma membrane ->
plasma membrane ARG80, ARG81, DAL81, PHD1, STP1
YLR178C TFS1 regulation of proteolysis and peptidolysis ->
catabolism, protein metabolism, regulation of metabolism lipid binding, protease inhibitor activity ->
lipid binding, protease inhibitor activity soluble fraction ->
soluble fraction
|YKR013W| PRY2 SWI4, SWI6
|YMR135C| GID8 negative regulation of gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main: regulation of metabolism (0.67) amino acid permease activity (0.33) plasma membrane (0.50) SWI4 PHD1 DAL81 (0.67)
Score: 0.33 0.00 0.00 0.667
P-value: 7.716E-03 (regulation of metabolism) 2.077E+00 (binding) 3.000E+00 (cell) 8.596E-02 (DAL81)

ALPHA1(1) AND ALPHA2(1) AND MCB(1) => SimExpr(YOR144C) OR SimExpr(other) : 5 2

EXPR: (0.191) ALPHA2 (P < 0.000) ALPHA1 (P < 0.000) MCB (P < 0.057)

ORF SYMBOL P F C TF
|YPL140C| MKK2 protein amino acid phosphorylation, signal transduction ->
phosphate metabolism, signal transduction, protein modification MAP kinase kinase activity ->
protein kinase activity intracellular ->
intracellular FKH1, FKH2
YNL082W PMS1 mismatch repair, meiosis ->
DNA repair, cell cycle, DNA metabolism ATPase activity, ATP binding, DNA binding ->
ATP binding, DNA binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides nuclear chromosome ->
intracellular MTH1
YFR027W ECO1 sister chromatid cohesion, DNA replication, DNA repair ->
DNA metabolism, cell cycle acetyltransferase activity ->
acyltransferase activity nuclear chromatin ->
intracellular
YOR284W HUA2 RFX1, YAP6
YPR185W APG13 protein-vacuolar targeting, autophagy ->
cytoplasm organization and biogenesis, autophagy, intracellular transport, protein metabolism, protein transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
|YJL095W| BCK1 protein amino acid phosphorylation, protein kinase cascade, response to nutrients, establishment of cell polarity (sensu Saccharomyces) ->
phosphate metabolism, intracellular signaling cascade, response to extracellular stimulus, cytoplasm organization and biogenesis, protein modification, response to chemical substance MAP kinase kinase kinase activity ->
protein kinase activity intracellular ->
intracellular YAP1
YOR144C ELG1 negative regulation of DNA transposition, negative regulation of DNA recombination ->
DNA metabolism YJL206C
Main: DNA metabolism (0.50) protein kinase activity (0.40) intracellular (0.80) MTH1 (0.17)
Score: 0.33 0.10 0.60 0.000
P-value: 3.096E-01 (protein amino acid phosphorylation) 3.795E-01 (protein kinase activity) 1.705E-01 (chromosome) 7.321E-01 (YJL206C)

ALPHA1(1) AND MCB(1) => SimExpr(YMR076C) OR SimExpr(other) : 22 10

MCB(1) AND CSRE(1) => SimExpr(YMR076C) OR SimExpr(other) : 5 2

ALPHA1(1) AND RPN4(1) AND mPROTEOL18(m_proteolysis_orfnum2SD_n18)(1) => SimExpr(YKL145W) OR SimExpr(other) : 5 2

EXPR: (0.219) mPROTEOL18(m_proteolysis_orfnum2SD_n18) (P < 0.003) RPN4 (P < 0.020) ALPHA1 (P < 0.002)

m_MERE4(1) AND m_RPE8(1) => SimExpr(YMR292W) OR SimExpr(other) : 5 2

ALPHA1(1) AND MCB(1) => SimExpr(YNL206C) OR SimExpr(other) : 22 10

m_nutritional_response_pathway_orfnum2SD_n7(1) AND m_g-proteins_orfnum2SD_n11(1) AND m_lipid_and_fatty-acid_transport_orfnum2SD_n11(1) => SimExpr(YOL033W) OR SimExpr(other) : 5 1

EXPR: (0.203) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_lipid_and_fatty-acid_transport_orfnum2SD_n11 (P < 0.000) m_nutritional_response_pathway_orfnum2SD_n7 (P < 0.000)

ORF SYMBOL P F C TF
YOR343C NO SYMBOL DIG1, RAP1, STE12
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
|YMR164C| MSS11 positive regulation of transcription from Pol II promoter, starch catabolism, pseudohyphal growth ->
carbohydrate metabolism, cell organization and biogenesis, polysaccharide metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, catabolism specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus
YOL033W MSE1 glutamyl-tRNA aminoacylation, protein biosynthesis ->
biosynthesis, protein metabolism glutamate-tRNA ligase activity ->
glutamate-tRNA ligase activity mitochondrion ->
cytoplasm CHA4, FHL1
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
cytoplasm GCN4
YAL061W NO SYMBOL
Main: cell organization and biogenesis (0.50) glutamate-tRNA ligase activity (0.25) cytoplasm (0.75) CHA4 (0.25)
Score: 0.50 0.00 0.50 0.000
P-value: 1.041E+00 (catabolism) 2.725E+00 (enzyme activity) 8.352E-01 (cytosol) 4.226E-01 (CHA4)

m_pentose-phosphate_pathway_orfnum2SD_n14(1) AND m_other_signal-transduction_activities_orfnum2SD_n13(1) => SimExpr(YDL134C) OR SimExpr(other) : 7 3

EXPR: (0.225) m_pentose-phosphate_pathway_orfnum2SD_n14 (P < 0.002) m_other_signal-transduction_activities_orfnum2SD_n13 (P < 0.002)

REB1(1) AND m_metal_ion_transporters_orfnum2SD_n6(1) => SimExpr(YML129C) OR SimExpr(other) : 5 2

m_organization_of_cell_wall_orfnum2SD_n6(1) AND PAC(1) => SimExpr(YIL096C) OR SimExpr(other) : 5 1

EXPR: (0.179) PAC (P < 0.003) m_organization_of_cell_wall_orfnum2SD_n6 (P < 0.000)

ORF SYMBOL P F C TF
YNL141W AAH1 adenine catabolism ->
nucleobase metabolism, catabolism adenine deaminase activity ->
adenine deaminase activity YFL044C
YIL096C NO SYMBOL GAT3, HAP2, MOT3, RTS2
YIL122W POG1 re-entry into mitotic cell cycle after pheromone arrest ->
cell cycle, conjugation with cellular fusion, perception of abiotic stimulus, sensory perception specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YNL299W TRF5 sister chromatid cohesion ->
cell cycle DNA-directed DNA polymerase activity ->
DNA-directed DNA polymerase activity nucleus ->
nucleus
YDR184C ATC1 response to stress, polar budding ->
response to stress, budding nucleus ->
nucleus ARO80, GLN3, SIP4, SKO1
|YMR094W| CTF13 centromere/kinetochore complex maturation ->
cell cycle centromeric DNA binding, DNA bending activity ->
centromeric DNA binding, DNA bending activity condensed nuclear chromosome kinetochore ->
condensed chromosome, chromosome, nucleus
Main: cell cycle (0.60) adenine deaminase activity (0.25) nucleus (1.00) RLM1 (0.25)
Score: 0.30 0.00 1.00 0.000
P-value: 2.757E-01 (cell cycle) 2.725E+00 (enzyme activity) 5.966E-01 (nucleus) 7.579E-01 (HAP2)

ABF1(1) AND ALPHA1'(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YNL059C) OR SimExpr(other) : 6 2

m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND REB1(1) => SimExpr(YOR122C) OR SimExpr(other) : 9 3

EXPR: (0.222) REB1 (P < 0.020) m_biogenesis_of_chromosome_structure_orfnum2SD_n9 (P < 0.001)

ORF SYMBOL P F C TF
|YOR128C| ADE2 purine base metabolism ->
aromatic compound metabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism phosphoribosylaminoimidazole carboxylase activity ->
phosphoribosylaminoimidazole carboxylase activity BAS1, HAP2, REB1, SFL1, YAP1
YOR122C PFY1 response to osmotic stress, axial budding, polar budding, actin polymerization and/or depolymerization ->
response to abiotic stimulus, asexual reproduction, cytoplasm organization and biogenesis protein binding ->
protein binding contractile ring (sensu Saccharomyces), actin cap (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoskeleton REB1
YFL005W SEC4 cytokinesis, Golgi to plasma membrane transport, nonselective vesicle fusion, polar budding, small GTPase mediated signal transduction, exocytosis ->
cell proliferation, budding, signal transduction, transport RAB small monomeric GTPase activity ->
RAB small monomeric GTPase activity actin cap (sensu Saccharomyces), transport vesicle ->
cell cortex, cytoplasm REB1
YML129C COX14 cytochrome c oxidase biogenesis, aerobic respiration ->
protein metabolism, energy pathways mitochondrial membrane, integral to membrane ->
cytoplasm, integral to membrane DOT6, MSS11, REB1
YOR021C NO SYMBOL ARG80, GCR2
|YJR137C| ECM17 sulfate assimilation, cell wall organization and biogenesis ->
sulfur metabolism, cell organization and biogenesis sulfite reductase (NADPH) activity ->
sulfite reductase (NADPH) activity ABF1, DOT6, GCR2, MET31, REB1
YOR223W NO SYMBOL CUP9, ROX1, YAP6
YDL232W OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
|YFL016C| MDJ1 protein folding, proteolysis and peptidolysis ->
protein metabolism, catabolism co-chaperone activity ->
co-chaperone activity mitochondrial inner membrane ->
cytoplasm, inner membrane HSF1, RAP1
YKR048C NAP1 nucleosome assembly, M phase of mitotic cell cycle ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation protein binding ->
protein binding nucleus ->
nucleus SKN7
YOR311C HSD1 integral to membrane, endoplasmic reticulum membrane\, intrinsic protein ->
integral to membrane, cytoplasm, endomembrane system CIN5
YKR028W SAP190 G1/S transition of mitotic cell cycle ->
cell proliferation protein serine/threonine phosphatase activity ->
protein serine/threonine phosphatase activity cytoplasm ->
cytoplasm PHO4, SMP1
Main: cell proliferation (0.33) protein binding (0.38) cytoplasm (0.75) REB1 (0.50)
Score: 0.22 0.11 0.57 0.242
P-value: 5.878E-02 (polar budding) 2.073E-01 (protein binding) 8.278E-02 (actin cap (sensu Saccharomyces)) 4.067E-05 (REB1)

SFF(1) AND m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND REB1(1) => SimExpr(YOR122C) OR SimExpr(other) : 7 1

EXPR: (0.196) SFF (P < 0.000) REB1 (P < 0.012) m_biogenesis_of_chromosome_structure_orfnum2SD_n9 (P < 0.002)

ORF SYMBOL P F C TF
YOR122C PFY1 response to osmotic stress, axial budding, polar budding, actin polymerization and/or depolymerization ->
response to abiotic stimulus, asexual reproduction, cytoplasm organization and biogenesis actin monomer binding ->
actin monomer binding contractile ring (sensu Saccharomyces), actin cap (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoskeleton REB1
YFL005W SEC4 cytokinesis, Golgi to plasma membrane transport, nonselective vesicle fusion, polar budding, small GTPase mediated signal transduction, exocytosis ->
cell proliferation, budding, signal transduction, transport RAB small monomeric GTPase activity ->
RAB small monomeric GTPase activity actin cap (sensu Saccharomyces), transport vesicle ->
cell cortex, cytoplasm REB1
YOR021C NO SYMBOL ARG80, GCR2
YOR223W NO SYMBOL CUP9, ROX1, YAP6
YDL232W OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
|YFL016C| MDJ1 protein folding, proteolysis and peptidolysis ->
protein metabolism, catabolism co-chaperone activity ->
co-chaperone activity mitochondrial inner membrane ->
cytoplasm, inner membrane HSF1, RAP1
YOR311C HSD1 integral to membrane, endoplasmic reticulum membrane\, intrinsic protein ->
integral to membrane, cytoplasm, endomembrane system CIN5
YKR028W SAP190 G1/S transition of mitotic cell cycle ->
cell proliferation protein serine/threonine phosphatase activity ->
protein serine/threonine phosphatase activity cytoplasm ->
cytoplasm PHO4, SMP1
Main: cell proliferation (0.40) RAB small monomeric GTPase activity (0.20) cytoplasm (0.83) REB1 (0.38)
Score: 0.20 0.00 0.73 0.107
P-value: 1.940E-02 (polar budding) 5.091E-01 (protein binding) 2.985E-02 (actin cap (sensu Saccharomyces)) 2.899E-02 (REB1)

SFF'(1) AND m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND REB1(1) => SimExpr(YOR122C) OR SimExpr(other) : 8 1

EXPR: (0.202) SFF' (P < 0.000) REB1 (P < 0.004) m_biogenesis_of_chromosome_structure_orfnum2SD_n9 (P < 0.002)

ORF SYMBOL P F C TF
YOR122C PFY1 response to osmotic stress, axial budding, polar budding, actin polymerization and/or depolymerization ->
response to abiotic stimulus, asexual reproduction, cytoplasm organization and biogenesis protein binding ->
protein binding contractile ring (sensu Saccharomyces), actin cap (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoskeleton REB1
YFL005W SEC4 cytokinesis, Golgi to plasma membrane transport, nonselective vesicle fusion, polar budding, small GTPase mediated signal transduction, exocytosis ->
cell proliferation, budding, signal transduction, transport RAB small monomeric GTPase activity ->
RAB small monomeric GTPase activity actin cap (sensu Saccharomyces), transport vesicle ->
cell cortex, cytoplasm REB1
YOR021C NO SYMBOL ARG80, GCR2
YOR223W NO SYMBOL CUP9, ROX1, YAP6
YDL232W OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
|YFL016C| MDJ1 protein folding, proteolysis and peptidolysis ->
protein metabolism, catabolism co-chaperone activity ->
co-chaperone activity mitochondrial inner membrane ->
cytoplasm, inner membrane HSF1, RAP1
YKR048C NAP1 nucleosome assembly, M phase of mitotic cell cycle ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation protein binding ->
protein binding nucleus ->
nucleus SKN7
YOR311C HSD1 integral to membrane, endoplasmic reticulum membrane\, intrinsic protein ->
integral to membrane, cytoplasm, endomembrane system CIN5
YKR028W SAP190 G1/S transition of mitotic cell cycle ->
cell proliferation protein serine/threonine phosphatase activity ->
protein serine/threonine phosphatase activity cytoplasm ->
cytoplasm PHO4, SMP1
Main: cell proliferation (0.50) protein binding (0.50) cytoplasm (0.71) REB1 (0.33)
Score: 0.27 0.20 0.52 0.083
P-value: 3.057E-02 (polar budding) 9.075E-02 (protein binding) 3.819E-02 (actin cap (sensu Saccharomyces)) 4.613E-02 (REB1)

m_lipid_and_fatty-acid_transport_orfnum2SD_n11(1) AND REB1(1) AND SCB(1) => SimExpr(YOR122C) : 5

EXPR: (0.150) m_lipid_and_fatty-acid_transport_orfnum2SD_n11 (P < 0.000) REB1 (P < 0.000) SCB (P < 0.000)

ORF SYMBOL P F C TF
YMR015C ERG5 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-22 sterol desaturase activity ->
C-22 sterol desaturase activity endoplasmic reticulum ->
cytoplasm PHD1, RAP1, YAP5
YMR121C RPL15B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex REB1
YOR122C PFY1 response to osmotic stress, axial budding, polar budding, actin polymerization and/or depolymerization ->
response to abiotic stimulus, asexual reproduction, cytoplasm organization and biogenesis actin monomer binding ->
actin monomer binding contractile ring (sensu Saccharomyces), actin cap (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoskeleton REB1
YPL237W SUI3 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
Main: biosynthesis (0.60) RNA binding (0.20) cytoplasm (0.80) REB1 (0.75)
Score: 0.50 0.00 0.60 0.500
P-value: 9.063E-01 (biosynthesis) 7.055E-01 (binding) 3.647E-01 (endoplasmic reticulum) 2.559E-03 (REB1)

PAC(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YLR336C) OR SimExpr(other) : 10 4

EXPR: (0.240) PAC (P < 0.027) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.000)

ALPHA2(1) AND PAC(1) AND mRRPE(1) => SimExpr(YKL172W) OR SimExpr(other) : 7 2

EXPR: (0.208) mRRPE (P < 0.001) ALPHA2 (P < 0.000) PAC (P < 0.010)

ORF SYMBOL P F C TF
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YKL172W EBP2 rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus ABF1, FZF1, RFX1
YMR049C ERB1 rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent RTG3
YNR046W NO SYMBOL ABF1
|YLR249W| YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus
YLR222C UTP13 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
YJR070C NO SYMBOL GAT3, YAP5
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
Main: RNA processing (0.71) RNA binding (0.50) nucleus (0.67) ABF1 (0.38)
Score: 0.52 0.17 0.53 0.107
P-value: 5.498E-05 (rRNA processing) 9.514E-01 (RNA binding) 2.344E-03 (nucleolus) 2.203E-01 (ABF1)

m_RRSE3(1) AND mRRPE(1) AND m_rRSE10(1) => SimExpr(YNL110C) OR SimExpr(other) : 7 1

mRRPE(1) AND m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5(1) AND m_rRSE10(1) => SimExpr(YNL110C) OR SimExpr(other) : 5 1

EXPR: (0.190) mRRPE (P < 0.001) m_metabolism_of_cyclic_and_unusual_nucleotides_orfnum2SD_n5 (P < 0.000) m_rRSE10 (P < 0.000)

ORF SYMBOL P F C TF
YGR145W ENP2
YNL110C NOP15 ribosomal large subunit biogenesis ->
ribosome biogenesis nucleus, nucleolus ->
nucleus, nucleolus
YLR197W SIK1 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus DAL81, HAL9
YNL132W KRE33
YJL148W RPA34 transcription from Pol I promoter ->
transcription from Pol I promoter DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex, nucleus, nucleolus ->
DNA-directed RNA polymerase I complex, nucleus, nucleolus AZF1, CHA4, CUP9, DAL81, DIG1, FZF1, GCR1, GCR2, GLN3, HAL9, HAP2, HAP3, HMS1, LEU3, MAC1, MBP1, MET31, MOT3, NDD1, PDR1, PHD1, REB1, RLM1, RME1, ROX1, RPH1, RTS2, SKN7, SWI5, YAP6, ZAP1
|YJL033W| HCA4 35S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleolus HIR2, USV1
Main: ribosome biogenesis (0.75) DNA-directed RNA polymerase activity (0.50) nucleolus (1.00) HAL9 DAL81 (0.67)
Score: 0.83 0.00 1.00 0.333
P-value: 1.559E-02 (transcription from Pol I promoter) 2.725E+00 (enzyme activity) 2.300E-04 (nucleolus) 6.238E-02 (HAL9)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND mRRPE(1) AND m_morphogenesis_orfnum2SD_n5(1) => SimExpr(YMR310C) OR SimExpr(other) : 6 2

EXPR: (0.223) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) mRRPE (P < 0.000) m_morphogenesis_orfnum2SD_n5 (P < 0.000)

m_nutritional_response_pathway_orfnum2SD_n7(1) AND PAC(1) AND mRRPE(1) => SimExpr(YMR310C) OR SimExpr(other) : 6 2

EXPR: (0.213) mRRPE (P < 0.000) m_nutritional_response_pathway_orfnum2SD_n7 (P < 0.000) PAC (P < 0.010)

ORF SYMBOL P F C TF
YMR310C NO SYMBOL
YKL172W EBP2 rRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription nucleolus ->
nucleus ABF1, FZF1, RFX1
|YOL022C| NO SYMBOL MAC1, MOT3, RTS2
YHR052W CIC1 protein catabolism ->
macromolecule catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription nucleolus ->
nucleus
|YMR014W| BUD22 bud site selection ->
cytokinesis, cytoplasm organization and biogenesis nucleus ->
nucleus CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YLR222C UTP13 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
snoRNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
Main: cytoplasm organization and biogenesis (0.80) protein binding\, bridging (0.50) nucleus (1.00) ABF1 (0.33)
Score: 0.60 0.00 1.00 0.067
P-value: 2.363E-02 (rRNA processing) 2.295E+00 (binding) 1.008E-03 (nucleolus) 1.000E+00

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_phosphate_utilization_orfnum2SD_n4(1) AND mRRPE(1) => SimExpr(YNL209W) OR SimExpr(other) : 7 3

EXPR: (0.213) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) mRRPE (P < 0.003) m_phosphate_utilization_orfnum2SD_n4 (P < 0.001)

ORF SYMBOL P F C TF
YOL123W HRP1 mRNA cleavage, mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cleavage/polyadenylation specificity factor activity ->
RNA binding mRNA cleavage factor complex, nucleus ->
nucleus
|YHR003C| NO SYMBOL HAP4, SWI6, THI2
|YGR145W| ENP2
YPL237W SUI3 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation regulator activity ribosome ->
cytoplasm, ribonucleoprotein complex
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation regulator activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
oxidoreductase activity\, acting on CH-OH group of donors mitochondrion ->
cytoplasm GCN4, MET4
YFL039C ACT1 cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter ->
transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex ->
cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex DIG1, ROX1, STE12
YNL209W SSB2 protein biosynthesis ->
biosynthesis, protein metabolism chaperone activity, ATPase activity ->
chaperone activity, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides polysome, cytoplasm ->
cytoplasm, ribonucleoprotein complex ABF1, RFX1
|YMR257C| PET111 protein biosynthesis ->
biosynthesis, protein metabolism translation regulator activity ->
translation regulator activity mitochondrial inner membrane ->
cytoplasm, inner membrane ARG80, ARO80, FZF1, GCR2, NRG1, RCS1, RTG1, SFP1, SRD1, STP1, THI2
YGL253W HXK2 fructose metabolism ->
alcohol metabolism, carbohydrate metabolism hexokinase activity ->
carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups nucleus, cytosol ->
nucleus, cytoplasm ABF1, CIN5, HSF1, SWI4
Main: biosynthesis (0.62) translation regulator activity (0.38) cytoplasm (0.88) ABF1 THI2 (0.29)
Score: 0.54 0.11 0.82 0.095
P-value: 3.186E-01 (protein biosynthesis) 8.198E-03 (translation regulator activity) 4.000E-01 (ribosome) 4.236E-02 (THI2)

SFF(1) AND m_amino-acid_transport_orfnum2SD_n13(1) AND m_amino-acid_transporters_orfnum2SD_n11(1) => SimExpr(YOR307C) OR SimExpr(other) : 5 2

EXPR: (0.224) SFF (P < 0.000) m_amino-acid_transport_orfnum2SD_n13 (P < 0.014) m_amino-acid_transporters_orfnum2SD_n11 (P < 0.007)

ALPHA1'(1) AND m_amino-acid_transporters_orfnum2SD_n11(1) AND m_breakdown_of_lipids_fatty_acids_and_isoprenoids_orfnum2SD_n8(1) => SimExpr(YOR307C) OR SimExpr(other) : 5 2

EXPR: (0.209) m_breakdown_of_lipids_fatty_acids_and_isoprenoids_orfnum2SD_n8 (P < 0.000) m_amino-acid_transporters_orfnum2SD_n11 (P < 0.002) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
YDR046C BAP3 amino acid transport ->
transport amino acid transporter activity ->
amino acid transporter activity plasma membrane ->
plasma membrane DAL81, STP1
YGR281W YOR1 transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane
YPL265W DIP5 amino acid transport ->
transport amino acid permease activity, amino acid transporter activity ->
amino acid permease activity, amino acid transporter activity plasma membrane ->
plasma membrane ARG80, ARG81, DAL81, PHD1, STP1
YOR307C SLY41 ER to Golgi transport ->
transport, vesicle-mediated transport PDR1
|YGR180C| RNR4 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity nucleus, cytoplasm ->
nucleus, cytoplasm CIN5, MBP1, RAP1, RFX1, SWI6
|YNL231C| PDR16 phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity cytoplasm ->
cytoplasm HSF1, MBP1, SWI4, YAP1
YGR279C SCW4 conjugation with cellular fusion ->
conjugation, sexual reproduction glucosidase activity ->
glucosidase activity cell wall (sensu Fungi) ->
cell wall (sensu Fungi) ASH1, IXR1, PHD1, SWI4
Main: transport (0.71) amino acid transporter activity (0.33) plasma membrane (0.50) SWI4 PHD1 DAL81 MBP1 STP1 (0.33)
Score: 0.48 0.07 0.27 0.267
P-value: 1.408E-02 (response to drug) 2.046E-02 (amino acid transporter activity) 5.322E-02 (plasma membrane) 5.898E-02 (STP1)

m_g-proteins_orfnum2SD_n13(1) AND REB1(1) => SimExpr(YDL007W) OR SimExpr(other) : 7 2

m_g-proteins_orfnum2SD_n13(1) AND REB1(1) AND ALPHA1'(1) => SimExpr(YDL007W) OR SimExpr(other) : 6 1

EXPR: (0.212) REB1 (P < 0.011) m_g-proteins_orfnum2SD_n13 (P < 0.000) ALPHA1' (P < 0.000)

ORF SYMBOL P F C TF
YMR139W RIM11 response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis, sporulation (sensu Saccharomyces) ->
response to stress, phosphorus metabolism, catabolism, sporulation, protein metabolism glycogen synthase kinase 3 activity ->
glycogen synthase kinase 3 activity MAL33, YJL206C
YKR011C NO SYMBOL SWI4, SWI6
YMR002W NO SYMBOL NDD1, REB1, SWI6
YOL148C SPT20 chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein binding ->
protein binding SAGA complex ->
nucleus GRF10(Pho2), MATa1, MIG1, PHO4
|YNL233W| BNI4 cytokinesis ->
cell proliferation protein binding ->
protein binding contractile ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoplasm PHO4
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YDL007W RPT2 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism ATPase activity, endopeptidase activity ->
ATPase activity, endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus REB1
Main: protein metabolism (0.60) protein binding (0.40) cytoplasm (0.50) REB1 (0.43)
Score: 0.30 0.10 0.33 0.238
P-value: 2.766E-01 (proteolysis and peptidolysis) 3.314E-01 (protein binding) 4.624E+00 (nucleus) 2.541E-02 (REB1)

m_phosphate_transport_orfnum2SD_n5(1) AND RPN4(1) => SimExpr(YDL007W) OR SimExpr(other) : 5 1

m_phosphate_utilization_orfnum2SD_n9(1) AND m_meiosis_orfnum2SD_n3(1) => SimExpr(YOR338W) : 5

ndt80(MSE)(1) AND m_metal_ion_transporters_orfnum2SD_n26(1) => SimExpr(YOR338W) : 5

m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND PAC(1) AND mRRPE(1) => SimExpr(YNL308C) OR SimExpr(other) : 7 3

EXPR: (0.216) mRRPE (P < 0.000) PAC (P < 0.001) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.000)

ORF SYMBOL P F C TF
YAL059W ECM1 cell wall organization and biogenesis ->
cell organization and biogenesis MOT3
|YDR496C| PUF6 RFX1
YNR046W NO SYMBOL ABF1
YDR184C ATC1 response to stress, polar budding ->
response to stress, asexual reproduction nucleus ->
nucleus ARO80, GLN3, SIP4, SKO1
YNL175C NOP13 RNA binding ->
RNA binding nucleolus, nucleoplasm ->
nucleus INO2, INO4
|YHR169W| DBP8 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
YNL308C KRI1 ribosome biogenesis ->
cell organization and biogenesis nucleolus ->
nucleus
YML125C NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
|YNR053C| NOG2 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleus, nucleolus, nucleoplasm ->
nucleus, nucleoplasm ABF1, AZF1
YNL112W DBP2 RNA helicase activity ->
RNA binding bud neck ->
site of polarized growth (sensu Fungi)
Main: cell organization and biogenesis (0.60) RNA binding (0.75) nucleus (0.83) ABF1 (0.29)
Score: 0.40 0.67 0.67 0.048
P-value: 8.341E-01 (ribosome biogenesis) 6.804E-02 (RNA helicase activity) 3.312E-03 (nucleolus) 1.000E+00

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_g-proteins_orfnum2SD_n11(1) AND LYS14(1) AND SCB(1) => SimExpr(YMR321C) OR SimExpr(other) : 5 1

EXPR: (0.183) m_g-proteins_orfnum2SD_n11 (P < 0.000) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) LYS14 (P < 0.000) SCB (P < 0.000)

ORF SYMBOL P F C TF
|YGR191W| HIP1 manganese ion transport, histidine transport ->
transport, organic acid transport histidine transporter activity ->
histidine transporter activity plasma membrane ->
plasma membrane GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
YPL218W SAR1 ER to Golgi transport ->
transport, vesicle-mediated transport SAR small monomeric GTPase activity ->
SAR small monomeric GTPase activity COPII vesicle coat ->
cytoplasm
YOR224C RPB8 transcription from Pol III promoter, transcription from Pol I promoter, transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase II\, core complex, DNA-directed RNA polymerase III complex, DNA-directed RNA polymerase I complex ->
nucleus, nucleolus ABF1
YMR321C NO SYMBOL
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transketolase activity cytoplasm ->
cytoplasm REB1
YGL202W ARO8 aromatic amino acid family metabolism ->
amine metabolism, aromatic compound metabolism, amino acid and derivative metabolism, organic acid metabolism aromatic amino acid transferase activity ->
aromatic amino acid transferase activity FZF1, MCM1, MOT3, YAP1
Main: transport (0.40) histidine transporter activity (0.20) cytoplasm (0.50) MCM1 YAP1 REB1 (0.50)
Score: 0.10 0.00 0.17 0.333
P-value: 2.492E+00 (transport) 2.158E-01 (transferase activity) 4.731E+00 (cytoplasm) 7.202E-02 (YAP1)

mRRPE(1) AND m_amino-acid_biosynthesis_orfnum2SD_n9(1) => SimExpr(YMR233W) OR SimExpr(other) : 5 1

EXPR: (0.189) mRRPE (P < 0.000) m_amino-acid_biosynthesis_orfnum2SD_n9 (P < 0.003)

SFF'(1) AND mRRPE(1) AND m_amino-acid_biosynthesis_orfnum2SD_n9(1) => SimExpr(YMR233W) : 5

EXPR: (0.174) SFF' (P < 0.000) mRRPE (P < 0.000) m_amino-acid_biosynthesis_orfnum2SD_n9 (P < 0.007)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND PAC(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YNL112W) OR SimExpr(other) : 11 4

EXPR: (0.202) m_other_morphogenetic_activities_orfnum2SD_n7 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000) ALPHA1' (P < 0.000)

m_other_morphogenetic_activities_orfnum2SD_n7(1) AND m_RRSE3(1) AND m_g-proteins_orfnum2SD_n12(1) AND PAC(1) => SimExpr(YNL112W) OR SimExpr(other) : 9 4

m_mitochondrial_biogenesis_orfnum2SD_n5(1) AND m_g-proteins_orfnum2SD_n12(1) AND PAC(1) AND mRRPE(1) => SimExpr(YNL112W) : 5

EXPR: (0.156) mRRPE (P < 0.000) m_g-proteins_orfnum2SD_n12 (P < 0.000) PAC (P < 0.002) m_mitochondrial_biogenesis_orfnum2SD_n5 (P < 0.000)

ORF SYMBOL P F C TF
YAL059W ECM1 cell wall organization and biogenesis ->
cell organization and biogenesis MOT3
YDR496C PUF6 RFX1
YNL308C KRI1 ribosome biogenesis ->
cell organization and biogenesis nucleolus ->
nucleolus
YNR053C NOG2 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism GTPase activity ->
GTPase activity nucleus, nucleolus, nucleoplasm ->
nucleus, nucleolus, nucleoplasm ABF1, AZF1
YNL112W DBP2 RNA helicase activity ->
RNA helicase activity bud neck ->
bud neck
Main: cell organization and biogenesis (0.67) RNA helicase activity (0.50) nucleolus (0.67) ABF1 (0.33)
Score: 0.33 0.00 0.33 0.000
P-value: 2.630E+00 (cell organization and biogenesis) 1.971E+00 (binding) 9.452E-02 (nucleolus) 2.433E-01 (AZF1)

MCB(1) AND m_deoxyribonucleotide_metabolism_orfnum2SD_n8(1) => SimExpr(YIL026C) : 7

m_phosphate_transport_orfnum2SD_n18(1) AND m_phosphate_metabolism_orfnum2SD_n16(1) => SimExpr(YAL007C) OR SimExpr(other) : 5 2

m_other_morphogenetic_activities_orfnum2SD_n8(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YGL098W) OR SimExpr(other) : 6 2

m_pheromone_response_generation_orfnum2SD_n10(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YGL098W) OR SimExpr(other) : 5 2

EXPR: (0.232) m_pheromone_response_generation_orfnum2SD_n10 (P < 0.018) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.009)

ORF SYMBOL P F C TF
YGR112W SHY1 respiratory gaseous exchange ->
respiratory gaseous exchange mitochondrial inner membrane ->
cytoplasm, inner membrane MIG1
|YDR101C| ARX1 ribosomal large subunit biogenesis ->
cell organization and biogenesis nucleoplasm, cytoplasm ->
nucleus, cytoplasm IXR1, RFX1
YAL002W VPS8 late endosome to vacuole transport ->
cell organization and biogenesis, transport membrane fraction ->
membrane fraction MBP1, PHD1
|YJR095W| SFC1 fumarate transport, succinate transport ->
transport succinate/fumarate antiporter activity ->
succinate/fumarate antiporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane CBF1, PHD1
YML087C NO SYMBOL
YDR116C MRPL1 protein biosynthesis, meiosis, aerobic respiration ->
biosynthesis, cell proliferation, energy pathways, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex CHA4, GRF10(Pho2)
YGL098W USE1 RCS1
Main: cell organization and biogenesis (0.40) succinate/fumarate antiporter activity (0.50) cytoplasm (0.80) PHD1 (0.33)
Score: 0.20 0.00 0.60 0.067
P-value: 3.004E+00 (cytoplasm organization and biogenesis) 2.000E+00 2.928E-01 (mitochondrial inner membrane) 1.614E-01 (PHD1)

m_allantoin_and_allantoate_transporters_orfnum2SD_n11(1) AND mRRPE(1) => SimExpr(YNL175C) OR SimExpr(other) : 7 3

m_other_proteolytic_degradation_orfnum2SD_n12(1) AND m_mitochondrial_biogenesis_orfnum2SD_n5(1) => SimExpr(YNL175C) OR SimExpr(other) : 5 1

m_allantoin_and_allantoate_transporters_orfnum2SD_n11(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YNL175C) OR SimExpr(other) : 6 2

EXPR: (0.206) mRRPE (P < 0.002) ALPHA1' (P < 0.000) m_allantoin_and_allantoate_transporters_orfnum2SD_n11 (P < 0.000)

m_other_energy_generation_activities_orfnum2SD_n11(1) AND m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn(1) => SimExpr(YML030W) OR SimExpr(other) : 7 2

EXPR: (0.216) m_other_energy_generation_activities_orfnum2SD_n11 (P < 0.006) m_other_cell_growth_cell_division_and_dna_synthesis_activities_orfnum2SD_n10.scn (P < 0.004)

ORF SYMBOL P F C TF
YGL187C COX4 aerobic respiration ->
energy derivation by oxidation of organic compounds cytochrome c oxidase activity ->
cytochrome c oxidase activity respiratory chain complex IV (sensu Eukarya) ->
cytoplasm, respiratory chain complex IV, membrane HAP2, HAP3, HAP4, HAP5
|YOL019W| NO SYMBOL SWI4
YML030W NO SYMBOL
YJL036W SNX4 autophagy, transport ->
autophagy, transport lipid binding ->
lipid binding membrane ->
membrane FKH2
YLR314C CDC3 cellular morphogenesis, cytokinesis, cell wall organization and biogenesis, axial budding, establishment of cell polarity (sensu Saccharomyces) ->
cellular morphogenesis, cytokinesis, external encapsulating structure organization and biogenesis, budding, cytoplasm organization and biogenesis structural constituent of cytoskeleton, lipid binding ->
structural constituent of cytoskeleton, lipid binding septin ring (sensu Saccharomyces), spore wall (sensu Fungi), prospore membrane, shmoo tip ->
cell wall, prospore, site of polarized growth (sensu Fungi), cell cortex, cytoskeleton SFP1
|YDR044W| HEM13 heme biosynthesis ->
pigment metabolism, pigment biosynthesis, coenzymes and prosthetic group biosynthesis, porphyrin metabolism coproporphyrinogen oxidase activity ->
coproporphyrinogen oxidase activity mitochondrial inner membrane ->
cytoplasm, membrane
YIL010W DOT5 regulation of redox homeostasis ->
cell redox homeostasis thioredoxin peroxidase activity ->
thioredoxin peroxidase activity nucleus ->
nucleus PHD1
YPR160W GPH1 glycogen catabolism ->
carbohydrate catabolism, polysaccharide metabolism, energy derivation by oxidation of organic compounds glycogen phosphorylase activity ->
glycogen phosphorylase activity cytoplasm ->
cytoplasm MAC1, MTH1, NDD1
YJR040W GEF1 cation homeostasis ->
cell ion homeostasis voltage-gated chloride channel activity ->
voltage-gated chloride channel activity Golgi vesicle ->
cytoplasm DOT6, MTH1
Main: energy derivation by oxidation of organic compounds (0.29) lipid binding (0.29) cytoplasm (0.57) MTH1 (0.29)
Score: 0.05 0.05 0.38 0.048
P-value: 1.967E-01 (cell homeostasis) 2.566E-02 (lipid binding) 4.766E-01 (mitochondrial inner membrane) 1.708E-01 (MTH1)

SFF(1) AND m_other_energy_generation_activities_orfnum2SD_n11(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n18(1) => SimExpr(YML030W) OR SimExpr(other) : 6 2

EXPR: (0.224) SFF (P < 0.003) m_other_nucleotide-metabolism_activities_orfnum2SD_n18 (P < 0.002) m_other_energy_generation_activities_orfnum2SD_n11 (P < 0.011)

ORF SYMBOL P F C TF
YNL071W LAT1 pyruvate metabolism ->
pyruvate metabolism dihydrolipoamide S-acetyltransferase activity ->
dihydrolipoamide S-acetyltransferase activity mitochondrion ->
mitochondrion
YML030W NO SYMBOL
YGR143W SKN1 cell wall organization and biogenesis, beta-1\,6 glucan biosynthesis ->
cell wall organization and biogenesis, beta-1\,6 glucan biosynthesis glucosidase activity ->
glucosidase activity integral to membrane ->
integral to membrane HSF1, MCM1, NDD1, RAP1, SMP1
YLR314C CDC3 cellular morphogenesis, cytokinesis, cell wall organization and biogenesis, axial budding, establishment of cell polarity (sensu Saccharomyces) ->
cellular morphogenesis, cytokinesis, cell wall organization and biogenesis, axial budding, establishment of cell polarity (sensu Saccharomyces) structural constituent of cytoskeleton, phosphatidylinositol binding ->
structural constituent of cytoskeleton, phosphatidylinositol binding septin ring (sensu Saccharomyces), spore wall (sensu Fungi), prospore membrane, shmoo tip ->
septin ring (sensu Saccharomyces), spore wall (sensu Fungi), prospore membrane, shmoo tip SFP1
YNL085W MKT1 viral life cycle ->
viral life cycle ABF1
|YML017W| PSP2
|YGR238C| KEL2 conjugation with cellular fusion ->
conjugation with cellular fusion shmoo tip, bud tip, bud neck ->
shmoo tip, bud tip, bud neck CIN5, INO2, INO4, MTH1, YAP6
YOR153W PDR5 drug transport, response to drug ->
drug transport, response to drug xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane YAP6
Main: cell wall organization and biogenesis (0.33) dihydrolipoamide S-acetyltransferase activity (0.25) shmoo tip (0.40) YAP6 (0.40)
Score: 0.07 0.00 0.10 0.100
P-value: 4.256E-01 (external encapsulating structure organization and biogenesis) 2.375E+00 (hydrolase activity) 4.648E-02 (shmoo) 3.591E-01 (YAP6)

SFF'(1) AND m_lipid_and_fatty-acid_transport_orfnum2SD_n11(1) AND m_ion_transporters_orfnum2SD_n11(1) => SimExpr(YKR039W) OR SimExpr(other) : 8 4

EXPR: (0.237) SFF' (P < 0.002) m_lipid_and_fatty-acid_transport_orfnum2SD_n11 (P < 0.004) m_ion_transporters_orfnum2SD_n11 (P < 0.007)

m_amino-acid_transport_orfnum2SD_n13(1) AND m_amino-acid_transport_orfnum2SD_n20(1) => SimExpr(YKR039W) OR SimExpr(other) : 9 2

EXPR: (0.209) m_amino-acid_transport_orfnum2SD_n13 (P < 0.003) m_amino-acid_transport_orfnum2SD_n20 (P < 0.000)

m_ion_transporters_orfnum2SD_n11(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YKR039W) OR SimExpr(other) : 5 2

EXPR: (0.226) m_ion_transporters_orfnum2SD_n11 (P < 0.014) m_amino-acid_transport_orfnum2SD_n18 (P < 0.026)

ORF SYMBOL P F C TF
YGR065C VHT1 biotin transport ->
transport biotin transporter activity ->
biotin transporter activity plasma membrane ->
plasma membrane
|YDR044W| HEM13 heme biosynthesis ->
pigment metabolism, coenzymes and prosthetic group biosynthesis, coenzymes and prosthetic group metabolism, biosynthesis, heterocycle metabolism coproporphyrinogen oxidase activity ->
coproporphyrinogen oxidase activity mitochondrial inner membrane ->
cytoplasm, inner membrane
YGR121C MEP1 ammonium transport ->
transport ammonium transporter activity ->
ammonium transporter activity plasma membrane ->
plasma membrane CIN5
YGR086C PIL1 ASH1, SWI5
YKL152C GPM1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphoglycerate mutase activity ->
phosphoglycerate mutase activity cytosol ->
cytoplasm GCR1, GCR2, HSF1, RAP1
YKR039W GAP1 amino acid transport ->
transport general amino acid permease activity ->
general amino acid permease activity integral to plasma membrane ->
integral to membrane, plasma membrane CIN5, YAP6
|YJL082W| IML2
Main: transport (0.60) ammonium transporter activity (0.20) plasma membrane (0.60) CIN5 (0.50)
Score: 0.40 0.00 0.40 0.167
P-value: 1.245E+00 (transport) 1.537E-01 (transporter activity) 5.322E-02 (plasma membrane) 4.086E-01 (CIN5)

m_nutritional_response_pathway_orfnum2SD_n8(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YKL014C) OR SimExpr(other) : 6 2

EXPR: (0.217) mRRPE (P < 0.000) ALPHA1' (P < 0.000) m_nutritional_response_pathway_orfnum2SD_n8 (P < 0.000)

ORF SYMBOL P F C TF
YGR090W UTP22 ZMS1
YKL014C NO SYMBOL ABF1
|YDR359C| VID21 ABF1
YMR309C NIP1 translational initiation ->
macromolecule biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity cytoplasm, eukaryotic translation initiation factor 3 complex ->
cytoplasm MTH1
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cytoplasm organization and biogenesis, cell cycle nucleus ->
nucleus
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription RNA binding ->
RNA binding nucleolus ->
nucleus
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation with cellular fusion, sporulation (sensu Fungi), cytoplasm organization and biogenesis, intracellular transport, protein metabolism, protein transport GTPase activity ->
GTPase activity cytoplasm ->
cytoplasm PHO4
|YMR013C| SEC59 protein-ER targeting, protein amino acid glycosylation ->
cytoplasm organization and biogenesis, macromolecule biosynthesis, intracellular transport, secretory pathway, protein modification, glycoprotein metabolism, protein metabolism, protein transport dolichol kinase activity ->
dolichol kinase activity membrane ->
membrane FHL1, NDD1, RAP1, RLM1, RME1
Main: cytoplasm organization and biogenesis (0.80) RNA binding (0.25) cytoplasm (0.40) ABF1 (0.33)
Score: 0.80 0.00 0.20 0.067
P-value: 8.277E-01 (cytoplasm organization and biogenesis) 2.059E+00 (nucleic acid binding) 5.009E+00 (nucleus) 4.840E-01 (ZMS1)

SFF'(1) AND m_phosphate_utilization_orfnum2SD_n4(1) AND PAC(1) => SimExpr(YKL014C) OR SimExpr(other) : 5 1

EXPR: (0.205) SFF' (P < 0.000) m_phosphate_utilization_orfnum2SD_n4 (P < 0.000) PAC (P < 0.024)

ORF SYMBOL P F C TF
YGR145W ENP2
YKL014C NO SYMBOL ABF1
|YLR249W| YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YGR158C MTR3 35S primary transcript processing, mRNA catabolism ->
cell organization and biogenesis, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism 3'-5' exoribonuclease activity ->
nuclease activity, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus ZMS1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YOR095C RKI1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity\, interconverting aldoses and ketoses FHL1, FKH2, RAP1
Main: cell organization and biogenesis (0.50) RNA binding (0.50) cytoplasm (0.67) ABF1 (0.25)
Score: 0.33 0.17 0.67 0.000
P-value: 5.271E-02 (35S primary transcript processing) 4.019E-01 (nucleic acid binding) 4.113E+00 (nucleus) 2.842E-01 (ZMS1)

m_deoxyribonucleotide_metabolism_orfnum2SD_n23(1) AND PAC(1) AND mRRPE(1) => SimExpr(YKL014C) : 5

EXPR: (0.168) mRRPE (P < 0.000) m_deoxyribonucleotide_metabolism_orfnum2SD_n23 (P < 0.000) PAC (P < 0.001)

ORF SYMBOL P F C TF
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YKL014C NO SYMBOL ABF1
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction GTPase activity ->
GTPase activity cytoplasm ->
cytoplasm PHO4
YNL075W IMP4 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription rRNA primary transcript binding ->
rRNA primary transcript binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex USV1
YNL292W PUS4 tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism pseudouridylate synthase activity ->
pseudouridylate synthase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.75) rRNA primary transcript binding (0.25) nucleus (0.75) ABF1 (0.20)
Score: 0.67 0.00 0.67 0.000
P-value: 1.660E-02 (RNA modification) 1.971E+00 (binding) 1.103E-01 (nucleolus) 3.157E-01 (USV1)

m_nitrogen_and_sulphur_transport_orfnum2SD_n9(1) AND m_other_cation_transporters_orfnum2SD_n18(1) => SimExpr(YGL006W) OR SimExpr(other) : 5 2

SFF(1) AND m_biogenesis_of_chromosome_structure_orfnum2SD_n9(1) AND REB1(1) => SimExpr(YOR021C) OR SimExpr(other) : 6 2

SFF'(1) AND LYS14(1) AND CCA(1) => SimExpr(YKL043W) OR SimExpr(other) : 5 1

EXPR: (0.184) CCA (P < 0.000) SFF' (P < 0.000) LYS14 (P < 0.000)

SFF(1) AND LYS14(1) AND CCA(1) => SimExpr(YKL043W) OR SimExpr(other) : 5 1

EXPR: (0.184) SFF (P < 0.000) CCA (P < 0.001) LYS14 (P < 0.000)

m_g-proteins_orfnum2SD_n11(1) AND m_allantoin_and_allantoate_transporters_orfnum2SD_n13(1) AND mRRPE(1) => SimExpr(YLR175W) OR SimExpr(other) : 5 2

EXPR: (0.209) m_g-proteins_orfnum2SD_n11 (P < 0.000) mRRPE (P < 0.003) m_allantoin_and_allantoate_transporters_orfnum2SD_n13 (P < 0.000)

ORF SYMBOL P F C TF
|YLR328W| NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity CIN5, MSN1, ROX1
|YHR104W| GRE3 response to stress, arabinose metabolism ->
response to stress, alcohol metabolism, carbohydrate metabolism aldehyde reductase activity ->
aldehyde reductase activity
YDR341C NO SYMBOL GCN4, ZMS1
YLR175W CBF5 rRNA modification, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription pseudouridylate synthase activity ->
pseudouridylate synthase activity small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex AZF1, HAL9
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
YJR129C NO SYMBOL DOT6, SIP4
Main: biosynthesis (0.40) nicotinamide-nucleotide adenylyltransferase activity (0.20) ribonucleoprotein complex (1.00) AZF1 (0.20)
Score: 0.20 0.00 1.00 0.000
P-value: 2.785E+00 (biosynthesis) 1.225E+00 (transferase activity) 8.282E-01 (ribonucleoprotein complex) 3.865E-01 (MSN1)

m_amino-acid_degradation_orfnum2SD_n8(1) AND m_g-proteins_orfnum2SD_n11(1) AND mRRPE(1) => SimExpr(YLR175W) : 5

m_g-proteins_orfnum2SD_n11(1) AND m_g-proteins_orfnum2SD_n13(1) AND mRRPE(1) => SimExpr(YLR175W) : 5

EXPR: (0.134) m_g-proteins_orfnum2SD_n11 (P < 0.000) mRRPE (P < 0.000) m_g-proteins_orfnum2SD_n13 (P < 0.000)

ORF SYMBOL P F C TF
YLR244C MAP1 proteolysis and peptidolysis ->
macromolecule catabolism, protein metabolism methionyl aminopeptidase activity ->
peptidase activity, metallopeptidase activity cytosolic ribosome (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
YLR175W CBF5 rRNA modification, 35S primary transcript processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription\, DNA-dependent pseudouridylate synthase activity ->
carbon-oxygen lyase activity small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex AZF1, HAL9
YKR059W TIF1 translational initiation ->
macromolecule biosynthesis, protein metabolism translation initiation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FKH1, FKH2
YFL045C SEC53 protein-ER targeting ->
cytoplasm organization and biogenesis, intracellular transport, secretory pathway, protein metabolism, protein transport phosphomannomutase activity ->
intramolecular transferase activity cytosol ->
cytoplasm
YPR080W TEF1 translational elongation ->
macromolecule biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
Main: protein metabolism (0.80) translation factor activity\, nucleic acid binding (0.40) cytoplasm (0.80) ABF1 (0.33)
Score: 0.70 0.10 0.90 0.000
P-value: 2.716E-01 (protein metabolism) 2.561E-02 (translation factor activity\, nucleic acid binding) 4.540E-03 (ribonucleoprotein complex) 5.106E-01 (HAL9)

SFF(1) AND m_other_signal-transduction_activities_orfnum2SD_n13(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YMR064W) OR SimExpr(other) : 5 2

EXPR: (0.240) SFF (P < 0.000) m_amino-acid_transport_orfnum2SD_n18 (P < 0.001) m_other_signal-transduction_activities_orfnum2SD_n13 (P < 0.001)

ORF SYMBOL P F C TF
|YPL277C| NO SYMBOL CIN5, MCM1, YJL206C
YMR064W AEP1 protein biosynthesis ->
protein biosynthesis MSN1
YGR177C ATF2 steroid metabolism ->
steroid metabolism alcohol O-acetyltransferase activity ->
alcohol O-acetyltransferase activity cytoplasm ->
cytoplasm INO4, MCM1
YLR278C NO SYMBOL INO4, MSN1
YJR138W IML1 ABF1, DOT6, GCR2, MET31, REB1
|YPR074C| TKL1 pentose-phosphate shunt ->
pentose-phosphate shunt transketolase activity ->
transketolase activity cytoplasm ->
cytoplasm REB1
YLR453C RIF2 telomerase-dependent telomere maintenance ->
telomerase-dependent telomere maintenance telomeric DNA binding ->
telomeric DNA binding nuclear telomere cap complex ->
nuclear telomere cap complex ABF1, GCR2, RTS2, SRD1, SWI6
Main: steroid metabolism (0.25) telomeric DNA binding (0.33) cytoplasm (0.67) GCR2 ABF1 INO4 MCM1 MSN1 REB1 (0.29)
Score: 0.00 0.00 0.33 0.238
P-value: 3.852E+00 (metabolism) 1.225E+00 (transferase activity) 4.869E+00 (cytoplasm) 4.488E-03 (MSN1)

SFF'(1) AND m_other_signal-transduction_activities_orfnum2SD_n13(1) AND m_amino-acid_transport_orfnum2SD_n18(1) => SimExpr(YMR064W) OR SimExpr(other) : 5 2

EXPR: (0.240) SFF' (P < 0.001) m_amino-acid_transport_orfnum2SD_n18 (P < 0.001) m_other_signal-transduction_activities_orfnum2SD_n13 (P < 0.004)

m_other_energy_generation_activities_orfnum2SD_n9(1) AND m_anion_transporters_orfnum2SD_n15(1) => SimExpr(YIL040W) OR SimExpr(other) : 5 2

m_RRSE3(1) AND PAC(1) AND mRRPE(1) => SimExpr(YHR052W) OR SimExpr(other) : 27 12

m_RRSE3(1) AND mRRPE(1) AND LYS14(1) => SimExpr(YHR052W) OR SimExpr(other) : 6 1

PAC(1) AND mRRPE(1) AND LYS14(1) => SimExpr(YHR052W) OR SimExpr(other) : 7 1

m_RRSE3(1) AND PAC(1) AND LYS14(1) => SimExpr(YHR052W) OR SimExpr(other) : 7 3

EXPR: (0.224) LYS14 (P < 0.000) m_RRSE3 (P < 0.000) PAC (P < 0.043)

ORF SYMBOL P F C TF
|YNL141W| AAH1 adenine catabolism ->
aromatic compound metabolism, catabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism adenine deaminase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds YFL044C
|YGR191W| HIP1 manganese ion transport, histidine transport ->
transport, organic acid transport histidine transporter activity ->
carboxylic acid transporter activity plasma membrane ->
plasma membrane GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
YHR052W CIC1 protein catabolism ->
catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleolus, cytosol, endoplasmic reticulum, nucleus HAP4, MATa1
YNL110C NOP15 ribosomal large subunit biogenesis ->
cell organization and biogenesis nucleus, nucleolus ->
nucleus, nucleolus
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleolus, nuclear membrane RAP1
YDR361C BCP1 ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleolus
YJR070C NO SYMBOL GAT3, YAP5
|YOL141W| PPM2 C-terminal protein carboxyl methyltransferase activity ->
transferase activity\, transferring one-carbon groups ARG81, SRD1
YML093W UTP14 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
Main: cell organization and biogenesis (0.50) RNA binding (0.33) nucleolus (0.83) YAP1 GLN3 (0.29)
Score: 0.40 0.07 0.67 0.048
P-value: 1.276E-01 (ribosome biogenesis) 1.130E+00 (RNA binding) 1.587E-04 (nucleolus) 1.374E-01 (GLN3)

m_other_pheromone_response_activities_orfnum2SD_n8(1) AND m_g-proteins_orfnum2SD_n11(1) AND m_glyoxylate_cycle_orfnum2SD_n8(1) => SimExpr(YMR284W) OR SimExpr(other) : 5 1

m_drug_transporters_orfnum2SD_n10(1) AND m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6(1) => SimExpr(YMR024W) OR SimExpr(other) : 5 2

SFF'(1) AND m_drug_transporters_orfnum2SD_n10(1) AND m_utilization_of_vitamins_cofactors_and_prosthetic_groups_orfnum2SD_n6(1) => SimExpr(YMR024W) : 5

PAC(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YGL099W) OR SimExpr(other) : 29 12

m_nutritional_response_pathway_orfnum2SD_n8(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YGL099W) OR SimExpr(other) : 6 2

PAC(1) AND mRRPE(1) AND m_other_nucleotide-metabolism_activities_orfnum2SD_n18(1) => SimExpr(YGL099W) OR SimExpr(other) : 6 2

EXPR: (0.196) mRRPE (P < 0.000) m_other_nucleotide-metabolism_activities_orfnum2SD_n18 (P < 0.000) PAC (P < 0.002)

AVERAGE SCORES:

P
  SCORE: 0.435 (Part of genes covered by "Main": 0.590) (No. rules=640/656)
  P-VALUE: 0.297
F
  SCORE: 0.182 (Part of genes covered by "Main": 0.416) (No. rules=621/654)
  P-VALUE: 0.258
C
  SCORE: 0.626 (Part of genes covered by "Main": 0.765) (No. rules=610/654)
  P-VALUE: 0.264
TF
  SCORE: 0.198 (Part of genes covered by "Main": 0.404) (No. rules=650/656)
  P-VALUE: 0.203
EXPRESSION: 0.892 (656)

ORF	SYMBOL	P	F	C	TF
\|YGR067C\|	NO SYMBOL				ABF1, ASH1, RGM1
YLR304C	ACO1	tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism -> carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis	aconitate hydratase activity -> aconitate hydratase activity	cytosol, mitochondrial matrix -> cytoplasm	CIN5, YAP6
\|YOR378W\|	NO SYMBOL				MTH1, RFX1, SWI4
YMR272C	SCS7	fatty acid metabolism -> lipid metabolism, organic acid metabolism	oxidoreductase activity -> oxidoreductase activity	endoplasmic reticulum -> cytoplasm	IXR1, SUM1
YGR281W	YOR1	transport, response to drug -> transport, response to abiotic stimulus	xenobiotic-transporting ATPase activity -> xenobiotic-transporting ATPase activity	plasma membrane -> plasma membrane
YPL250C	ICY2				HSF1, MET4
YDR281C	PHM6				PHO4, SUM1
YLR441C	RPS1A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, YAP5
Main:		biosynthesis (0.50)	aconitate hydratase activity (0.25)	cytoplasm (0.75)	SUM1 (0.29)
Score:		0.33	0.00	0.50	0.048
P-value:		5.696E-01 (carboxylic acid metabolism)	2.641E+00 (enzyme activity)	1.346E+00 (cytosol)	1.413E-01 (SUM1)

ORF	SYMBOL	P	F	C	TF
\|YFL004W\|	VTC2	protein localization, vacuole fusion (non-autophagic) -> protein metabolism, cell organization and biogenesis		vacuolar membrane -> cytoplasm	CIN5, GCN4, STE12, YAP1, YAP6
\|YLR335W\|	NUP2	mRNA-nucleus export, rRNA-nucleus export, snRNA-nucleus export, tRNA-nucleus export, NLS-bearing substrate-nucleus import, snRNP protein-nucleus import, mRNA-binding (hnRNP) protein-nucleus import, ribosomal protein-nucleus import, protein-nucleus export, nuclear pore organization and biogenesis -> intracellular transport, intracellular protein transport, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transport	structural molecule activity -> structural molecule activity	nuclear pore -> nucleus, integral to membrane, endomembrane system
\|YGR244C\|	LSC2	tricarboxylic acid cycle, succinyl-CoA metabolism -> carbohydrate metabolism, coenzymes and prosthetic group metabolism, energy pathways	succinate-CoA ligase (ADP-forming) activity -> ligase activity\, forming carbon-sulfur bonds	mitochondrion -> cytoplasm	ARO80
YLR304C	ACO1	tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism -> carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis	aconitate hydratase activity -> carbon-oxygen lyase activity	cytosol, mitochondrial matrix -> cytoplasm	CIN5, YAP6
YLR168C	NO SYMBOL				HAP4
YFR033C	QCR6	aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c -> energy pathways, electron transport, phosphorus metabolism	ubiquinol-cytochrome c reductase activity -> oxidoreductase activity\, acting on diphenols and related substances as donors, primary active transporter activity, cation transporter activity	mitochondrion, respiratory chain complex III (sensu Eukarya) -> cytoplasm, respiratory chain complex III, inner membrane	HAP4, MBP1
YGR281W	YOR1	transport, response to drug -> transport, response to abiotic stimulus	xenobiotic-transporting ATPase activity -> purine nucleotide binding, multidrug transporter activity, primary active transporter activity, hydrolase activity\, acting on acid anhydrides	plasma membrane -> plasma membrane
YNR001C	CIT1	tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis -> carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis	citrate (SI)-synthase activity -> carbon-carbon lyase activity	mitochondrial matrix, mitochondrion -> cytoplasm	RGM1
YGR086C	PIL1				ASH1, SWI5
YOR136W	IDH2	tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis -> carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis	isocitrate dehydrogenase (NAD+) activity -> oxidoreductase activity\, acting on CH-OH group of donors	mitochondrial matrix, mitochondrion -> cytoplasm	MET4
Main:		energy pathways (0.62)	primary active transporter activity (0.29)	cytoplasm (0.75)	HAP4 YAP6 CIN5 (0.25)
Score:		0.43	0.05	0.54	0.071
P-value:		1.679E-06 (tricarboxylic acid cycle)	1.956E-01 (primary active transporter activity)	4.344E-02 (mitochondrion)	9.811E-02 (HAP4)

ORF	SYMBOL	P	F	C	TF
\|YMR056C\|	AAC1	ATP/ADP exchange -> purine nucleotide transport	ATP/ADP antiporter activity -> ATP/ADP antiporter activity	mitochondrial inner membrane -> mitochondrion, inner membrane	DAL81, NRG1, RCS1
YNL098C	RAS2	pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction -> pseudohyphal growth, sporulation (sensu Saccharomyces), G-protein coupled receptor protein signaling pathway, RAS protein signal transduction, cyclic-nucleotide-mediated signaling	RAS small monomeric GTPase activity -> RAS small monomeric GTPase activity	plasma membrane -> plasma membrane	ACE2, SKN7
\|YML111W\|	BUL2	protein polyubiquitination, protein monoubiquitination -> proteolysis and peptidolysis, protein modification			PDR1, SMP1, SWI5, YAP5
YMR086W	NO SYMBOL				FKH1
YLR304C	ACO1	tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism -> tricarboxylic acid cycle, TCA intermediate metabolism, amino acid biosynthesis, propionate metabolism, glutamine family amino acid metabolism, carboxylic acid metabolism	aconitate hydratase activity -> aconitate hydratase activity	cytosol, mitochondrial matrix -> cytosol, mitochondrion	CIN5, YAP6
YPR145W	ASN1	asparagine biosynthesis -> amino acid biosynthesis, aspartate family amino acid metabolism	asparagine synthase (glutamine-hydrolyzing) activity -> asparagine synthase (glutamine-hydrolyzing) activity		DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YMR134W	NO SYMBOL				BAS1, CIN5, FZF1, HAP3, RCS1
Main:		amino acid biosynthesis (0.40)	aconitate hydratase activity (0.25)	mitochondrion (0.67)	RCS1 CIN5 DAL81 (0.29)
Score:		0.10	0.00	0.33	0.143
P-value:		2.105E-01 (amino acid biosynthesis)	2.414E+00 (enzyme activity)	1.630E+00 (mitochondrion)	1.146E-01 (DAL81)

ORF	SYMBOL	P	F	C	TF
YGR035C	NO SYMBOL				CIN5, MET4, SMP1, YAP6
YLR304C	ACO1	tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism -> carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis	aconitate hydratase activity -> aconitate hydratase activity	cytosol, mitochondrial matrix -> cytoplasm	CIN5, YAP6
YML116W	ATR1	multidrug transport -> transport, response to abiotic stimulus	multidrug efflux pump activity -> multidrug efflux pump activity	plasma membrane -> plasma membrane	CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YML026C	RPS18B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, RGM1, SWI4, YAP5
YKL141W	SDH3	oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle -> electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways	succinate dehydrogenase activity -> succinate dehydrogenase activity	respiratory chain complex II (sensu Eukarya) -> cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
Main:		energy pathways (0.50)	aconitate hydratase activity (0.25)	cytoplasm (0.75)	YAP6 CIN5 (0.75)
Score:		0.33	0.00	0.50	0.500
P-value:		2.303E-03 (tricarboxylic acid cycle)	2.509E+00 (enzyme activity)	7.999E-01 (cytosol)	6.015E-03 (YAP6)

ORF	SYMBOL	P	F	C	TF
\|YOR213C\|	SAS5	chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	acetyltransferase activity -> acetyltransferase activity	nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome	GRF10(Pho2), SUM1
YNL096C	RPS7B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, SFP1
YPR080W	TEF1	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	FHL1, PDR1, RAP1, YAP5
YLR441C	RPS1A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, YAP5
YML026C	RPS18B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, RGM1, SWI4, YAP5
YGR254W	ENO1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity	phosphopyruvate hydratase complex, cytoplasm -> cytoplasm	FKH2, MSN4, PDR1, SWI5, YAP5
Main:		biosynthesis (0.83)	structural constituent of ribosome (0.50)	cytoplasm (0.83)	RAP1 YAP5 FHL1 (0.67)
Score:		0.67	0.20	0.67	0.600
P-value:		1.770E-02 (biosynthesis)	2.066E-02 (structural constituent of ribosome)	1.614E-03 (cytosolic small ribosomal subunit (sensu Eukarya))	1.154E-05 (YAP5)

ORF	SYMBOL	P	F	C	TF
YGR214W	RPS0A	protein biosynthesis, ribosomal small subunit assembly and maintenance -> protein biosynthesis, ribosomal small subunit assembly and maintenance	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, RAP1
YMR194W	RPL36A	protein biosynthesis -> protein biosynthesis	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
\|YPL189W\|	GUP2			membrane -> membrane	RFX1
YMR230W	RPS10B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, RAP1
YOR096W	RPS7A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, FKH2, RAP1
YML026C	RPS18B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, GAT3, RAP1, RGM1, SWI4, YAP5
\|YNL288W\|	CAF40	regulation of transcription from Pol II promoter -> regulation of transcription from Pol II promoter		CCR4-NOT complex -> transcription factor complex	RAP1
Main:		protein biosynthesis (0.83)	structural constituent of ribosome (1.00)	cytosolic ribosome (sensu Eukarya) (0.71)	RAP1 (0.86)
Score:		0.67	1.00	0.48	0.714
P-value:		2.810E-03 (protein biosynthesis)	6.519E-05 (structural constituent of ribosome)	4.548E-05 (cytosolic ribosome (sensu Eukarya))	6.246E-06 (RAP1)

ORF	SYMBOL	P	F	C	TF
YPL090C	RPS6A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, GAT3, INO4, RAP1, YAP5
YMR142C	RPL13B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, GAT3, RAP1, RGM1, YAP5
YIL018W	RPL2B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5
YGL030W	RPL30	protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytosolic ribosome (sensu Eukarya), cytoplasm, large ribosomal subunit	FHL1, GAT3, RAP1, SFP1
YML026C	RPS18B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, GAT3, RAP1, RGM1, SWI4, YAP5
YML073C	RPL6A	protein biosynthesis, ribosomal large subunit assembly and maintenance -> protein biosynthesis, ribosomal large subunit assembly and maintenance	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, GAT3, RAP1, YAP5
Main:		protein biosynthesis (1.00)	structural constituent of ribosome (1.00)	cytosolic ribosome (sensu Eukarya) (1.00)	RAP1 GAT3 FHL1 (1.00)
Score:		1.00	1.00	1.00	1.000
P-value:		3.014E-05 (protein biosynthesis)	2.028E-07 (structural constituent of ribosome)	1.144E-07 (cytosolic ribosome (sensu Eukarya))	1.489E-10 (GAT3)

ORF	SYMBOL	P	F	C	TF
YMR220W	ERG8	ergosterol biosynthesis, isoprenoid biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	phosphomevalonate kinase activity -> phosphomevalonate kinase activity	cytosol -> cytoplasm
\|YKL164C\|	PIR1	intracellular protein transport, cell wall organization and biogenesis -> cell organization and biogenesis, transport	structural constituent of cell wall -> structural constituent of cell wall	cell wall -> cell wall	BAS1, MCM1, PHD1, SMP1, SWI5
YMR024W	MRPL3	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	mitochondrial large ribosomal subunit -> cytoplasm, ribonucleoprotein complex
YDR276C	PMP3	cation transport -> transport		plasma membrane -> plasma membrane	GAT1
\|YGL262W\|	NO SYMBOL				YJL206C
YML116W	ATR1	multidrug transport -> transport, response to abiotic stimulus	multidrug efflux pump activity -> multidrug efflux pump activity	plasma membrane -> plasma membrane	CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YNL208W	NO SYMBOL				INO2
Main:		transport (0.60)	structural constituent of cell wall (0.25)	cytoplasm (0.40)	PHD1 (0.40)
Score:		0.40	0.00	0.20	0.100
P-value:		1.245E+00 (transport)	4.947E-01 (structural molecule activity)	4.928E-01 (plasma membrane)	2.510E-01 (PHD1)

ORF	SYMBOL	P	F	C	TF
YKR042W	UTH1	mitochondrion organization and biogenesis -> organelle organization and biogenesis		cell wall, mitochondrial outer membrane -> cell wall, cytoplasm, outer membrane	ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
YGR086C	PIL1				ASH1, SWI5
\|YGL049C\|	TIF4632	translational initiation -> protein biosynthesis	translation initiation factor activity -> translation initiation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex
YDR381W	YRA1	mRNA-nucleus export -> nucleocytoplasmic transport, RNA localization	RNA binding -> RNA binding	transcription export complex -> nucleus	ARO80
YNL096C	RPS7B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, SFP1
YOR096W	RPS7A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, FKH2, RAP1
\|YOR173W\|	DCS2				CAD1
YIL133C	RPL16A	protein biosynthesis -> protein biosynthesis	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, PUT3, RAP1, RGM1, SFP1, SMP1, YAP5
Main:		protein biosynthesis (0.67)	structural constituent of ribosome (0.60)	cytoplasm (0.83)	RAP1 FHL1 (0.43)
Score:		0.40	0.40	0.67	0.238
P-value:		8.546E-02 (protein biosynthesis)	7.389E-02 (structural constituent of ribosome)	2.798E-02 (ribosome)	3.006E-02 (FHL1)

ORF	SYMBOL	P	F	C	TF
\|YKR092C\|	SRP40	nucleocytoplasmic transport -> nucleocytoplasmic transport	chaperone activity -> chaperone activity	nucleolus -> nucleolus	CUP9, MET4, RAP1
YGL147C	RPL9A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, MBP1, RAP1, SWI4
YLR344W	RPL26A	protein biosynthesis -> protein biosynthesis	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, RAP1
YMR142C	RPL13B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, GAT3, RAP1, RGM1, YAP5
YOR096W	RPS7A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, FKH2, RAP1
YGL030W	RPL30	protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytosolic ribosome (sensu Eukarya), cytoplasm, large ribosomal subunit	FHL1, GAT3, RAP1, SFP1
YKL006W	RPL14A	protein biosynthesis -> protein biosynthesis	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
Main:		protein biosynthesis (0.86)	structural constituent of ribosome (0.86)	cytosolic ribosome (sensu Eukarya) (0.86)	RAP1 (1.00)
Score:		0.71	0.71	0.71	1.000
P-value:		1.466E-04 (protein biosynthesis)	2.360E-06 (structural constituent of ribosome)	5.663E-07 (cytosolic ribosome (sensu Eukarya))	3.382E-08 (RAP1)

ORF	SYMBOL	P	F	C	TF
YOL121C	RPS19A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	AZF1, FHL1, GCR1, GCR2, HAL9, MET31, MOT3, PDR1, RAP1, ROX1, RPH1, SMP1, YAP6, ZAP1
YNL302C	RPS19B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YDR309C	GIC2	axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) -> axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces)	small GTPase regulatory/interacting protein activity -> small GTPase regulatory/interacting protein activity	actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site -> cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm	ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6
YDR462W	MRPL28	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	mitochondrial large ribosomal subunit -> cytoplasm, ribonucleoprotein complex	ABF1
YKL180W	RPL17A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1
YOR096W	RPS7A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, FKH2, RAP1
\|YOR173W\|	DCS2				CAD1
Main:		protein biosynthesis (0.83)	structural constituent of ribosome (0.83)	cytoplasm (1.00)	RAP1 FHL1 (0.57)
Score:		0.67	0.67	1.00	0.286
P-value:		2.810E-03 (protein biosynthesis)	6.519E-05 (structural constituent of ribosome)	7.943E-04 (ribosome)	7.286E-04 (FHL1)

ORF	SYMBOL	P	F	C	TF
YLR406C	RPL31B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, FKH1, MTH1, RAP1
YNL302C	RPS19B	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, RAP1
YKL180W	RPL17A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytosolic ribosome (sensu Eukarya), cytoplasm, large ribosomal subunit	FHL1, GAT3, RAP1
YOR096W	RPS7A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, FKH2, RAP1
YIL133C	RPL16A	protein biosynthesis -> protein biosynthesis	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, GAT3, PDR1, PUT3, RAP1, RGM1, SFP1, SMP1, YAP5
Main:		protein biosynthesis (1.00)	structural constituent of ribosome (1.00)	cytosolic ribosome (sensu Eukarya) (1.00)	RAP1 FHL1 (1.00)
Score:		1.00	1.00	1.00	1.000
P-value:		1.632E-04 (protein biosynthesis)	3.434E-06 (structural constituent of ribosome)	2.686E-06 (cytosolic ribosome (sensu Eukarya))	2.760E-07 (FHL1)

ORF	SYMBOL	P	F	C	TF
YLR412W	NO SYMBOL
YJR145C	RPS4A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> cytosolic ribosome (sensu Eukarya), cytoplasm, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YNL162W	RPL42A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit	FHL1, RAP1, YAP5
YDR450W	RPS18A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YKL180W	RPL17A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytosolic ribosome (sensu Eukarya), cytoplasm, large ribosomal subunit	FHL1, GAT3, RAP1
YOR096W	RPS7A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit	FHL1, FKH2, RAP1
Main:		protein biosynthesis (1.00)	structural constituent of ribosome (1.00)	cytosolic ribosome (sensu Eukarya) (1.00)	RAP1 FHL1 (1.00)
Score:		1.00	1.00	1.00	1.000
P-value:		8.867E-04 (protein biosynthesis)	1.959E-05 (structural constituent of ribosome)	1.554E-05 (cytosolic ribosome (sensu Eukarya))	1.617E-06 (FHL1)

ORF	SYMBOL	P	F	C	TF
\|YNL234W\|	NO SYMBOL				SFL1, SKN7
YLR406C	RPL31B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, FKH1, MTH1, RAP1
YJR145C	RPS4A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YNL069C	RPL16B	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YNL162W	RPL42A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1, YAP5
YML073C	RPL6A	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, YAP5
YOR136W	IDH2	tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis -> carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis	isocitrate dehydrogenase (NAD+) activity -> isocitrate dehydrogenase (NAD+) activity	mitochondrial matrix, mitochondrion -> cytoplasm	MET4
\|YPL034W\|	NO SYMBOL				CRZ1, FZF1, GAL4, GCR2, IME4, NRG1, RCS1, RGM1, SFP1, SRD1, UGA3, YAP5, YFL044C, YJL206C
\|YLR353W\|	BUD8	pseudohyphal growth, bud site selection -> cell proliferation, cell organization and biogenesis		incipient bud site, bud tip -> incipient bud site, site of polarized growth (sensu Fungi)	FKH1, GAT1, RTG1, SFL1, UGA3, USV1
YIL052C	RPL34B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	RME1
\|YDR322W\|	MRPL35	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	mitochondrial large ribosomal subunit -> cytoplasm, ribonucleoprotein complex	CHA4, SUM1
YKL180W	RPL17A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1
YOR153W	PDR5	drug transport, response to drug -> transport, response to abiotic stimulus	xenobiotic-transporting ATPase activity -> xenobiotic-transporting ATPase activity	plasma membrane -> plasma membrane	YAP6
Main:		biosynthesis (0.82)	structural constituent of ribosome (0.80)	cytoplasm (0.82)	RAP1 FHL1 (0.46)
Score:		0.67	0.62	0.65	0.282
P-value:		2.699E-04 (protein biosynthesis)	1.353E-06 (structural constituent of ribosome)	9.062E-07 (large ribosomal subunit)	3.123E-05 (FHL1)

ORF	SYMBOL	P	F	C	TF
YOR070C	GYP1	vesicle-mediated transport -> transport	Rab GTPase activator activity -> GTPase activator activity	Golgi apparatus -> cytoplasm	SFP1
YIL123W	SIM1	microtubule cytoskeleton organization and biogenesis -> cell organization and biogenesis		cell wall -> cell wall	DIG1, FKH2, GRF10(Pho2), MCM1, STE12, SWI4, SWI6
YOR316C	COT1	cobalt ion transport, zinc ion transport, zinc ion homeostasis -> cell homeostasis, transport, cell ion homeostasis	di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity -> di-\, tri-valent inorganic cation transporter activity, zinc ion transporter activity, transition metal ion transporter activity	vacuole (sensu Fungi) -> cytoplasm	FKH2, INO2, INO4, NDD1, RAP1
YOL122C	SMF1	manganese ion transport -> transport	manganese ion transporter activity -> di-\, tri-valent inorganic cation transporter activity, transition metal ion transporter activity	plasma membrane, vacuole (sensu Fungi) -> plasma membrane, cytoplasm
\|YPL021W\|	ECM23	cell wall organization and biogenesis, pseudohyphal growth -> cell organization and biogenesis			NRG1
YGR035C	NO SYMBOL				CIN5, MET4, SMP1, YAP6
\|YMR144W\|	NO SYMBOL				FKH2, MBP1, MCM1, MSN4, MSS11, NDD1, SWI4, SWI6, YAP1
Main:		transport (0.60)	di-\, tri-valent inorganic cation transporter activity (0.67)	cytoplasm (0.75)	FKH2 (0.50)
Score:		0.40	0.33	0.50	0.200
P-value:		2.132E-02 (transition metal ion transport)	8.652E-03 (transition metal ion transporter activity)	5.479E-02 (storage vacuole)	1.685E-02 (FKH2)

ORF	SYMBOL	P	F	C	TF
\|YOR245C\|	DGA1	lipid storage, triacylglycerol biosynthesis -> transport, glycerol ether metabolism, biosynthesis, lipid metabolism	diacylglycerol O-acyltransferase activity -> diacylglycerol O-acyltransferase activity	lipid particle -> cytoplasm
YML116W	ATR1	multidrug transport -> transport, response to abiotic stimulus	multidrug efflux pump activity -> multidrug efflux pump activity	plasma membrane -> plasma membrane	CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YIL123W	SIM1	microtubule cytoskeleton organization and biogenesis -> cell organization and biogenesis		cell wall -> cell wall	DIG1, FKH2, GRF10(Pho2), MCM1, STE12, SWI4, SWI6
YOR316C	COT1	cobalt ion transport, zinc ion transport, zinc ion homeostasis -> cell homeostasis, transport, cell ion homeostasis	di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity -> di-\, tri-valent inorganic cation transporter activity, cobalt ion transporter activity, zinc ion transporter activity	vacuole (sensu Fungi) -> cytoplasm	FKH2, INO2, INO4, NDD1, RAP1
YGR035C	NO SYMBOL				CIN5, MET4, SMP1, YAP6
YMR135C	GID8	negative regulation of gluconeogenesis -> alcohol metabolism, carbohydrate metabolism, regulation of metabolism, biosynthesis, energy derivation by oxidation of organic compounds			ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
Main:		transport (0.60)	cobalt ion transporter activity (0.33)	cytoplasm (0.50)	YAP6 FKH2 (0.60)
Score:		0.40	0.00	0.17	0.800
P-value:		8.341E-01 (transport)	4.458E-01 (transporter activity)	4.731E+00 (cytoplasm)	1.171E-02 (FKH2)

ORF	SYMBOL	P	F	C	TF
\|YNL019C\|	NO SYMBOL
YLR378C	SEC61	SRP-dependent cotranslational membrane targeting\, translocation -> cell organization and biogenesis, protein metabolism, transport	protein transporter activity -> protein transporter activity	endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon -> cytoplasm, endoplasmic reticulum, endomembrane system	MAL13, REB1
YGR086C	PIL1				ASH1, SWI5
YJL158C	CIS3	cell wall organization and biogenesis -> cell organization and biogenesis	structural constituent of cell wall -> structural constituent of cell wall	cell wall, bud tip, endoplasmic reticulum, plasma membrane -> cell wall, site of polarized growth (sensu Fungi), cytoplasm, plasma membrane	FKH2, NDD1, PHD1, REB1, RLM1, SKN7, SWI4, SWI6
YKL122C	SRP21	protein-ER targeting -> cell organization and biogenesis, protein metabolism, transport	signal sequence binding -> signal sequence binding	nucleus, signal recognition particle -> nucleus, cytoplasm	REB1
YPR041W	TIF5	regulation of translational initiation, mature ribosome assembly -> cell organization and biogenesis, biosynthesis, protein metabolism	GTPase activator activity, translation initiation factor activity -> GTPase activator activity, translation initiation factor activity	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
Main:		cell organization and biogenesis (1.00)	signal sequence binding (0.25)	cytoplasm (1.00)	REB1 (0.75)
Score:		1.00	0.00	1.00	0.500
P-value:		9.931E-03 (protein-ER targeting)	1.806E+00 (binding)	4.489E-02 (endoplasmic reticulum)	1.095E-02 (REB1)

ORF	SYMBOL	P	F	C	TF
YOR022C	NO SYMBOL
\|YNL162W\|	RPL42A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1, YAP5
YMR250W	GAD1	response to oxidative stress, glutamate catabolism -> response to oxidative stress, glutamate catabolism	glutamate decarboxylase activity -> glutamate decarboxylase activity	cytoplasm -> cytoplasm
YJL082W	IML2
YPR124W	CTR1	protein biosynthesis, copper ion import -> protein biosynthesis, copper ion import	copper uptake transporter activity -> copper uptake transporter activity	plasma membrane -> plasma membrane	CIN5, INO2, INO4, MAC1, SMP1
YJL005W	CYR1	meiosis, G-protein signaling\, coupled to cAMP nucleotide second messenger, RAS protein signal transduction, regulation of cell cycle -> meiosis, G-protein signaling\, coupled to cAMP nucleotide second messenger, RAS protein signal transduction, regulation of cell cycle	adenylate cyclase activity -> adenylate cyclase activity	plasma membrane -> plasma membrane
YHL043W	ECM34	cell wall organization and biogenesis -> cell wall organization and biogenesis
Main:		protein biosynthesis (0.40)	glutamate decarboxylase activity (0.25)	cytoplasm (0.50)	INO2 (0.50)
Score:		0.10	0.00	0.33	0.000
P-value:		1.916E+00 (protein biosynthesis)	8.699E-02 (lyase activity)	4.928E-01 (plasma membrane)	8.282E-01 (INO2)

ORF	SYMBOL	P	F	C	TF
YNL241C	ZWF1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	glucose-6-phosphate 1-dehydrogenase activity -> oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor	cytoplasm -> cytoplasm	ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
\|YPR010C\|	RPA135	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> nucleotidyltransferase activity	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
\|YOR092W\|	ECM3	cell wall organization and biogenesis -> cell organization and biogenesis	ATPase activity -> adenyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides		STE12, YAP1
YKL085W	MDH1	tricarboxylic acid cycle, malate metabolism -> carbohydrate metabolism, organic acid metabolism, energy pathways	L-malate dehydrogenase activity -> malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor	mitochondrial matrix -> cytoplasm	IME4, MTH1, RTG1, YJL206C
YLR304C	ACO1	tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism -> carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis	aconitate hydratase activity -> hydro-lyase activity	cytosol, mitochondrial matrix -> cytoplasm	CIN5, YAP6
YNL098C	RAS2	pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction -> cell organization and biogenesis, sporulation, signal transduction	RAS small monomeric GTPase activity -> guanyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides	plasma membrane -> plasma membrane	ACE2, SKN7
YLR185W	RPL37A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1, RGM1, YAP5
YOR153W	PDR5	drug transport, response to drug -> transport, response to abiotic stimulus	xenobiotic-transporting ATPase activity -> adenyl nucleotide binding, multidrug transporter activity, P-P-bond-hydrolysis-driven transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides	plasma membrane -> plasma membrane	YAP6
Main:		carbohydrate metabolism (0.38)	hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides (0.38)	cytoplasm (0.57)	ACE2 SKN7 YAP6 IME4 (0.25)
Score:		0.18	0.14	0.33	0.107
P-value:		1.024E-02 (tricarboxylic acid cycle)	2.087E-01 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor)	3.674E-01 (mitochondrial matrix)	6.311E-02 (IME4)

ORF	SYMBOL	P	F	C	TF
YKL142W	MRP8	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	mitochondrial ribosome -> cytoplasm, ribonucleoprotein complex	ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YNL241C	ZWF1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	glucose-6-phosphate 1-dehydrogenase activity -> glucose-6-phosphate 1-dehydrogenase activity	cytoplasm -> cytoplasm	ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YGR254W	ENO1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity	phosphopyruvate hydratase complex, cytoplasm -> cytoplasm	FKH2, MSN4, PDR1, SWI5, YAP5
YFL039C	ACT1	cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter -> transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation	structural constituent of cytoskeleton -> structural constituent of cytoskeleton	actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex -> cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex	DIG1, ROX1, STE12
YLR205C	HMX1	iron ion homeostasis -> cell homeostasis	peroxidase activity, heme binding, heme oxygenase (decyclizing) activity -> peroxidase activity, heme binding, heme oxygenase (decyclizing) activity	membrane -> membrane	MAL13, PHO4, SKN7
\|YMR291W\|	NO SYMBOL				RAP1
YPL203W	TPK2	protein amino acid phosphorylation, pseudohyphal growth, RAS protein signal transduction -> phosphorus metabolism, cell organization and biogenesis, signal transduction, protein metabolism	protein serine/threonine kinase activity, cAMP-dependent protein kinase activity -> protein serine/threonine kinase activity, cAMP-dependent protein kinase activity	cytoplasm, cAMP-dependent protein kinase complex -> cytoplasm, cAMP-dependent protein kinase complex
YNL098C	RAS2	pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction -> cell organization and biogenesis, sporulation, signal transduction	RAS small monomeric GTPase activity -> RAS small monomeric GTPase activity	plasma membrane -> membrane	ACE2, SKN7
Main:		cell organization and biogenesis (0.43)	phosphopyruvate hydratase activity (0.14)	cytoplasm (0.71)	SKN7 (0.57)
Score:		0.33	0.00	0.52	0.333
P-value:		2.431E-02 (RAS protein signal transduction)	7.298E-01 (oxidoreductase activity)	3.201E+00 (cytoplasm)	2.619E-03 (SKN7)

ORF	SYMBOL	P	F	C	TF
YOL012C	HTZ1	chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging	chromatin binding -> chromatin binding	chromatin assembly complex, nuclear chromatin -> nucleus, chromosome	SWI4
YKL035W	UGP1	protein amino acid glycosylation, UDP-glucose metabolism -> biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism	UTP-glucose-1-phosphate uridylyltransferase activity -> UTP-glucose-1-phosphate uridylyltransferase activity
\|YOR374W\|	ALD4	ethanol metabolism -> alcohol metabolism	aldehyde dehydrogenase (NAD+) activity -> aldehyde dehydrogenase (NAD+) activity	mitochondrion -> cytoplasm	RAP1
YPL111W	CAR1	arginine catabolism to ornithine -> amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism	arginase activity -> arginase activity	cytosol -> cytoplasm	GCN4
YMR291W	NO SYMBOL				RAP1
YAR035W	YAT1	carnitine metabolism, alcohol metabolism -> amine metabolism, alcohol metabolism, organic acid metabolism, vitamin metabolism, amino acid and derivative metabolism	carnitine O-acetyltransferase activity -> carnitine O-acetyltransferase activity	mitochondrion -> cytoplasm
\|YIR016W\|	NO SYMBOL				DAL82, RAP1
Main:		alcohol metabolism (0.60)	chromatin binding (0.20)	cytoplasm (0.75)	RAP1 (0.60)
Score:		0.50	0.00	0.50	0.300
P-value:		2.268E-02 (alcohol metabolism)	1.225E+00 (transferase activity)	1.397E+00 (mitochondrion)	2.546E-02 (RAP1)

ORF	SYMBOL	P	F	C	TF
\|YOL011W\|	PLB3	phosphoinositide metabolism, phosphatidylserine catabolism -> catabolism, lipid metabolism	lysophospholipase activity -> lysophospholipase activity	extracellular space, plasma membrane -> extracellular space, plasma membrane	SWI4
YJR016C	ILV3	branched chain family amino acid biosynthesis -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	dihydroxy-acid dehydratase activity -> dihydroxy-acid dehydratase activity	mitochondrion -> cytoplasm
YKR071C	DRE2				CAD1, HSF1, YAP1, YAP3
\|YMR003W\|	NO SYMBOL
YML006C	GIS4	intracellular signaling cascade -> signal transduction			SKN7
YMR108W	ILV2	branched chain family amino acid biosynthesis -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	acetolactate synthase activity -> acetolactate synthase activity	mitochondrion -> cytoplasm	HSF1, LEU3
YPR074C	TKL1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	transketolase activity -> transketolase activity	cytoplasm -> cytoplasm	REB1
YHR063C	PAN5	pantothenate biosynthesis -> biosynthesis, coenzymes and prosthetic group metabolism	gluconate 5-dehydrogenase activity -> gluconate 5-dehydrogenase activity		MBP1, SWI4
Main:		biosynthesis (0.50)	gluconate 5-dehydrogenase activity (0.20)	cytoplasm (0.75)	SWI4 HSF1 (0.33)
Score:		0.33	0.00	0.50	0.133
P-value:		1.088E-02 (branched chain family amino acid biosynthesis)	1.135E-01 (lyase activity)	1.710E+00 (mitochondrion)	1.351E-01 (HSF1)

ORF	SYMBOL	P	F	C	TF
\|YPL084W\|	BRO1	signal transduction, vacuolar transport, ubiquitin-dependent protein catabolism -> signal transduction, cell organization and biogenesis, catabolism, transport, protein metabolism	intracellular transporter activity -> intracellular transporter activity	cytoplasm, endosome -> cytoplasm	HAA1
YPL020C	ULP1	G2/M transition of mitotic cell cycle, protein desumoylation -> cell proliferation, protein metabolism	cysteine-type peptidase activity, SUMO-specific protease activity -> cysteine-type peptidase activity, SUMO-specific protease activity	nuclear membrane, nuclear pore -> nucleus, integral to membrane, endomembrane system	ADR1
YJR016C	ILV3	branched chain family amino acid biosynthesis -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	dihydroxy-acid dehydratase activity -> dihydroxy-acid dehydratase activity	mitochondrion -> cytoplasm
YMR122C	NO SYMBOL				SWI5
YLR355C	ILV5	branched chain family amino acid biosynthesis, mitochondrial genome maintenance -> amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	ketol-acid reductoisomerase activity -> ketol-acid reductoisomerase activity	mitochondrion -> cytoplasm	GCN4, MET4
YMR108W	ILV2	branched chain family amino acid biosynthesis -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	acetolactate synthase activity -> acetolactate synthase activity	mitochondrion -> cytoplasm	HSF1, LEU3
Main:		biosynthesis (0.60)	acetolactate synthase activity (0.20)	cytoplasm (0.80)	HSF1 (0.20)
Score:		0.50	0.00	0.60	0.000
P-value:		3.562E-05 (branched chain family amino acid biosynthesis)	6.351E-02 (lyase activity)	1.995E-01 (mitochondrion)	1.805E-02 (HAA1)

ORF	SYMBOL	P	F	C	TF
YJL164C	TPK1	pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction -> cell organization and biogenesis, phosphorus metabolism, signal transduction, protein metabolism	protein serine/threonine kinase activity, cAMP-dependent protein kinase activity -> phosphotransferase activity\, alcohol group as acceptor	cytoplasm, cAMP-dependent protein kinase complex -> cytoplasm, cAMP-dependent protein kinase complex	DOT6, SFL1
YNL241C	ZWF1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	glucose-6-phosphate 1-dehydrogenase activity -> oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor	cytoplasm -> cytoplasm	ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YGR254W	ENO1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphopyruvate hydratase activity -> hydro-lyase activity	phosphopyruvate hydratase complex, cytoplasm -> cytoplasm	FKH2, MSN4, PDR1, SWI5, YAP5
\|YOL012C\|	HTZ1	chromatin silencing at HML and HMR (sensu Saccharomyces), regulation of transcription from Pol II promoter -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging	chromatin binding -> chromatin binding	chromatin assembly complex, nuclear chromatin -> nucleus, chromosome	SWI4
YKL085W	MDH1	tricarboxylic acid cycle, malate metabolism -> carbohydrate metabolism, organic acid metabolism, energy pathways	L-malate dehydrogenase activity -> malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor	mitochondrial matrix -> cytoplasm	IME4, MTH1, RTG1, YJL206C
\|YFL039C\|	ACT1	cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter -> transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation	structural constituent of cytoskeleton -> structural constituent of cytoskeleton	actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex -> cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex	DIG1, ROX1, STE12
YLR205C	HMX1	iron ion homeostasis -> cell homeostasis	peroxidase activity, heme binding, heme oxygenase (decyclizing) activity -> peroxidase activity, heme binding, oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, miscellaneous	membrane -> membrane	MAL13, PHO4, SKN7
YOR374W	ALD4	ethanol metabolism -> alcohol metabolism	aldehyde dehydrogenase (NAD+) activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor	mitochondrion -> cytoplasm	RAP1
YPL111W	CAR1	arginine catabolism to ornithine -> amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism	arginase activity -> hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in linear amidines	cytosol -> cytoplasm	GCN4
YDR381W	YRA1	mRNA-nucleus export -> transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	transcription export complex -> nucleus	ARO80
Main:		cell organization and biogenesis (0.30)	oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.20)	cytoplasm (0.70)	SKN7 PHO4 FKH2 SWI5 IME4 (0.20)
Score:		0.29	0.02	0.53	0.067
P-value:		5.321E-02 (main pathways of carbohydrate metabolism)	3.907E-02 (oxidoreductase activity)	1.314E+00 (nucleoplasm)	1.122E-01 (IME4)

ORF	SYMBOL	P	F	C	TF
YLR362W	STE11	protein amino acid phosphorylation, pseudohyphal growth, signal transduction during conjugation with cellular fusion -> phosphorus metabolism, cell organization and biogenesis, signal transduction, conjugation, protein metabolism, perception of external stimulus, sexual reproduction, response to abiotic stimulus	MAP kinase kinase kinase activity -> protein kinase activity	cytoplasm -> cytoplasm	HIR1
\|YNL080C\|	NO SYMBOL				GRF10(Pho2), INO4
YJL164C	TPK1	pseudohyphal growth, protein amino acid phosphorylation, RAS protein signal transduction -> cell organization and biogenesis, phosphorus metabolism, signal transduction, protein metabolism	protein serine/threonine kinase activity, cAMP-dependent protein kinase activity -> protein kinase activity	cytoplasm, cAMP-dependent protein kinase complex -> cytoplasm, cAMP-dependent protein kinase complex	DOT6, SFL1
YNL241C	ZWF1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	glucose-6-phosphate 1-dehydrogenase activity -> glucose-6-phosphate 1-dehydrogenase activity	cytoplasm -> cytoplasm	ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YOR348C	PUT4	neutral amino acid transport -> transport	amino acid permease activity, neutral amino acid transporter activity -> amino acid-polyamine transporter activity, neutral amino acid transporter activity	plasma membrane -> plasma membrane	SWI5
YAR042W	SWH1				SUM1
YPL109C	NO SYMBOL
\|YDR134C\|	NO SYMBOL				ASH1, NRG1, SOK2, SWI4
YIL048W	NEO1	intracellular protein transport -> transport	calcium-transporting ATPase activity, phospholipid-translocating ATPase activity -> ATP binding, aminophospholipid transporter activity, calcium ion transporter activity, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides		ABF1, GLN3, UGA3
YKL167C	MRP49	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	mitochondrial large ribosomal subunit -> cytoplasm, ribonucleoprotein complex	ABF1, IME4, IXR1
\|YPR165W\|	RHO1	cell wall organization and biogenesis, bud growth, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization -> asexual reproduction, signal transduction, cell organization and biogenesis	Rho small monomeric GTPase activity, signal transducer activity -> GTP binding, signal transducer activity, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides	1\,3-beta-glucan synthase complex, bud tip, bud neck, shmoo tip -> plasma membrane, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces)	ABF1
YDL079C	MRK1	response to stress, protein amino acid phosphorylation, proteolysis and peptidolysis -> response to stress, phosphorus metabolism, catabolism, protein metabolism	glycogen synthase kinase 3 activity -> protein kinase activity		MTH1
YNL098C	RAS2	pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction -> cell organization and biogenesis, sporulation, signal transduction	RAS small monomeric GTPase activity -> GTP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides	plasma membrane -> plasma membrane	ACE2, SKN7
Main:		cell organization and biogenesis (0.44)	protein kinase activity (0.33)	cytoplasm (0.57)	ABF1 (0.25)
Score:		0.36	0.17	0.43	0.106
P-value:		3.459E-02 (pseudohyphal growth)	1.763E-01 (protein serine/threonine kinase activity)	3.275E-01 (plasma membrane)	1.774E-01 (IME4)

ORF	SYMBOL	P	F	C	TF
YML012W	ERV25	ER to Golgi transport -> transport, vesicle-mediated transport		COPII-coated vesicle -> intracellular	ABF1
YPR135W	CTF4	DNA dependent DNA replication, DNA repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation	DNA binding -> DNA binding	nucleus -> intracellular	BAS1, DIG1, FZF1
YLR313C	SPH1	actin filament organization, polar budding, pseudohyphal growth, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) -> asexual reproduction, signal transduction, cell organization and biogenesis	cytoskeletal regulatory protein binding -> protein binding	polarisome, actin cap (sensu Saccharomyces), shmoo tip -> site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), intracellular	GCR1, RPH1
\|YLR430W\|	SEN1	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> intracellular	ARG80, GTS1, HAP5, RTG3, SIP4
\|YPL140C\|	MKK2	protein amino acid phosphorylation, signal transduction -> phosphorus metabolism, signal transduction, protein metabolism	MAP kinase kinase activity -> transferase activity\, transferring phosphorus-containing groups	intracellular -> intracellular	FKH1, FKH2
YNL102W	POL1	DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis -> DNA metabolism, cell proliferation	alpha DNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	alpha DNA polymerase\:primase complex -> intracellular	LEU3, MBP1
\|YMR125W\|	STO1	mRNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	mRNA binding -> RNA binding	commitment complex, snRNA cap binding complex -> intracellular	ABF1, FZF1, HAP3, MET31, RTG1, SRD1, SUM1, YAP6, ZAP1
YJR030C	NO SYMBOL				MBP1, PHO4, RTG1, SWI6
\|YNR028W\|	CPR8		peptidyl-prolyl cis-trans isomerase activity -> cis-trans isomerase activity		ASH1, DIG1, MCM1
YMR179W	SPT21	regulation of transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			MBP1, STB1, SWI4, SWI6, UGA3
YNL082W	PMS1	mismatch repair, meiosis -> DNA metabolism, cell proliferation	ATPase activity, ATP binding, DNA binding -> purine nucleotide binding, DNA binding, hydrolase activity\, acting on acid anhydrides	nuclear chromosome -> intracellular	MTH1
YGR109C	CLB6	regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis -> cell proliferation, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	cyclin-dependent protein kinase\, regulator activity -> transferase activity\, transferring phosphorus-containing groups, protein kinase regulator activity		MBP1, STB1, SWI4, SWI6
YFR027W	ECO1	sister chromatid cohesion, DNA replication, DNA repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation	acetyltransferase activity -> transferase activity\, transferring acyl groups	nuclear chromatin -> intracellular
YKR077W	NO SYMBOL
YNL077W	APJ1		chaperone activity -> chaperone activity		HSF1, MSN4
YOL006C	TOP1	negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration -> cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA topoisomerase type I activity -> other isomerase activity	nucleus -> intracellular	REB1
YNL039W	BDP1	transcription initiation from Pol III promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA polymerase III transcription factor activity -> RNA polymerase III transcription factor activity	transcription factor TFIIIB complex -> intracellular
YGR189C	CRH1			cell wall, incipient bud site -> cell wall, intracellular	GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YNL233W	BNI4	cytokinesis -> cell proliferation	protein binding -> protein binding	contractile ring (sensu Saccharomyces) -> site of polarized growth (sensu Fungi), intracellular	PHO4
YDR097C	MSH6	mismatch repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation	ATPase activity, ATP binding, DNA binding -> purine nucleotide binding, DNA binding, hydrolase activity\, acting on acid anhydrides	nucleus -> intracellular	DOT6, MBP1, SWI6
YGR085C	RPL11B	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural molecule activity	cytosolic large ribosomal subunit (sensu Eukarya) -> intracellular	FHL1, MIG1
YOR284W	HUA2				RFX1, YAP6
\|YDR134C\|	NO SYMBOL				ASH1, NRG1, SOK2, SWI4
\|YMR102C\|	NO SYMBOL
YNL206C	RTT106	negative regulation of DNA transposition -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			MSS11, SIP4, SUM1
YPR185W	APG13	protein-vacuolar targeting, autophagy -> cell organization and biogenesis, autophagy, protein metabolism, transport	protein binding -> protein binding	extrinsic to membrane -> extrinsic to membrane	MET4, SWI6
\|YJL095W\|	BCK1	protein amino acid phosphorylation, protein kinase cascade, response to nutrients, establishment of cell polarity (sensu Saccharomyces) -> phosphorus metabolism, signal transduction, response to extracellular stimulus, cell organization and biogenesis, protein metabolism, response to abiotic stimulus	MAP kinase kinase kinase activity -> transferase activity\, transferring phosphorus-containing groups	intracellular -> intracellular	YAP1
YMR076C	PDS5	mitotic sister chromatid cohesion, mitotic chromosome condensation -> cell proliferation, cell cycle	structural molecule activity -> structural molecule activity	condensed nuclear chromosome -> intracellular	FKH2, MBP1, SWI6
\|YGL225W\|	VRG4	nucleotide-sugar transport, N-linked glycosylation, lipid glycosylation -> transport, biosynthesis, lipid metabolism, protein metabolism	nucleotide-sugar transporter activity -> nucleotide-sugar transporter activity	Golgi apparatus -> intracellular
YOR144C	ELG1	negative regulation of DNA transposition, negative regulation of DNA recombination -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			YJL206C
YDL003W	MCD1	mitotic sister chromatid cohesion, mitotic chromosome condensation -> cell proliferation, cell cycle		nuclear cohesin complex -> intracellular	CIN5, MBP1, SWI6
YML027W	YOX1	negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle -> transcription, cell cycle	specific transcriptional repressor activity, DNA binding -> specific transcriptional repressor activity, DNA binding	nucleus -> intracellular	MBP1, SWI4, SWI6
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.46)	DNA binding (0.19)	intracellular (0.95)	MBP1 (0.33)
Score:		0.42	0.09	0.90	0.162
P-value:		1.223E-03 (DNA replication)	2.092E+00 (isomerase activity)	5.299E-01 (chromosome)	1.349E-05 (MBP1)

ORF	SYMBOL	P	F	C	TF
\|YLR212C\|	TUB4	microtubule nucleation, mitotic spindle assembly (sensu Saccharomyces) -> cell organization and biogenesis, cell proliferation, cell cycle	structural constituent of cytoskeleton -> structural constituent of cytoskeleton	inner plaque of spindle pole body, outer plaque of spindle pole body -> cytoplasm
YIL026C	IRR1	mitotic sister chromatid cohesion, colony morphology, germination (sensu Saccharomyces), cytogamy -> cell organization and biogenesis, sporulation, plasma membrane fusion, sporulation (sensu Fungi), cell proliferation, conjugation, sexual reproduction	protein binding -> protein binding	nuclear cohesin complex -> chromosome, nucleus	ABF1, MAL33, MBP1, SWI6
YFR027W	ECO1	sister chromatid cohesion, DNA replication, DNA repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation	acetyltransferase activity -> acetyltransferase activity	nuclear chromatin -> chromosome, nucleus
YNL039W	BDP1	transcription initiation from Pol III promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA polymerase III transcription factor activity -> RNA polymerase III transcription factor activity	transcription factor TFIIIB complex -> nucleus
YGR189C	CRH1			cell wall, incipient bud site -> cell wall, incipient bud site	GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YKL042W	SPC42	microtubule nucleation, spindle pole body duplication (sensu Saccharomyces) -> cell organization and biogenesis, cell proliferation	structural constituent of cytoskeleton -> structural constituent of cytoskeleton	intermediate layer of spindle pole body, central plaque of spindle pole body -> cytoplasm
\|YIL066C\|	RNR3	DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ribonucleoside-diphosphate reductase activity -> ribonucleoside-diphosphate reductase activity	cytoplasm -> cytoplasm	RFX1, STB1
Main:		cell proliferation (0.83)	structural constituent of cytoskeleton (0.33)	cytoplasm (0.43)	MBP1 (0.67)
Score:		0.80	0.07	0.29	0.333
P-value:		3.752E-04 (DNA replication and chromosome cycle)	2.692E-02 (structural constituent of cytoskeleton)	9.987E-02 (spindle pole body)	2.025E-01 (MBP1)

ORF	SYMBOL	P	F	C	TF
YOR343C	NO SYMBOL				DIG1, RAP1, STE12
YJR030C	NO SYMBOL				MBP1, PHO4, RTG1, SWI6
\|YNR028W\|	CPR8		peptidyl-prolyl cis-trans isomerase activity -> peptidyl-prolyl cis-trans isomerase activity		ASH1, DIG1, MCM1
YGL163C	RAD54	double-strand break repair via synthesis-dependent strand annealing, heteroduplex formation, double-strand break repair via break-induced replication, telomerase-independent telomere maintenance, double-strand break repair via single-strand annealing, chromatin modeling -> mating-type switching/recombination, chromosome organization and biogenesis (sensu Eukarya), DNA repair, response to DNA damage, DNA metabolism	DNA supercoiling activity, DNA dependent ATPase activity -> DNA supercoiling activity, DNA dependent ATPase activity	nucleus -> nucleus
YGR189C	CRH1			cell wall, incipient bud site -> cell wall, incipient bud site	GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YNL233W	BNI4	cytokinesis -> cytokinesis	protein binding -> protein binding	contractile ring (sensu Saccharomyces) -> site of polarized growth (sensu Fungi), cell cortex, cytoplasm	PHO4
YGR085C	RPL11B	protein biosynthesis, ribosomal large subunit assembly and maintenance -> macromolecule biosynthesis, cytoplasm organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, MIG1
YIL140W	AXL2	axial budding, bud site selection -> budding, cytokinesis, cytoplasm organization and biogenesis		integral to plasma membrane, bud, bud neck, septin ring -> integral to membrane, bud, site of polarized growth (sensu Fungi), cell cortex, plasma membrane	STB1, SWI4
Main:		cytoplasm organization and biogenesis (0.50)	peptidyl-prolyl cis-trans isomerase activity (0.25)	cell cortex (0.40)	SWI4 PHO4 MBP1 DIG1 STE12 (0.29)
Score:		0.33	0.00	0.20	0.238
P-value:		1.033E-01 (cytokinesis)	3.060E+00 (binding)	1.457E-01 (bud neck)	1.038E-01 (DIG1)

ORF	SYMBOL	P	F	C	TF
YDL130W	RPP1B	protein biosynthesis, translational elongation -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAL4, RAP1, RFX1
YOR348C	PUT4	neutral amino acid transport -> transport	amino acid permease activity, neutral amino acid transporter activity -> transporter activity	plasma membrane -> plasma membrane	SWI5
YOR063W	RPL3	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	GRF10(Pho2)
\|YHR178W\|	STB5	response to xenobiotic stimulus -> response to abiotic stimulus	transcription factor activity -> DNA binding	nucleus -> nucleus
YFR033C	QCR6	aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c -> energy pathways, electron transport, phosphorus metabolism	ubiquinol-cytochrome c reductase activity -> oxidoreductase activity\, acting on diphenols and related substances as donors, transporter activity	mitochondrion, respiratory chain complex III (sensu Eukarya) -> cytoplasm, respiratory chain complex III, inner membrane	HAP4, MBP1
\|YNL233W\|	BNI4	cytokinesis -> cell proliferation	protein binding -> protein binding	contractile ring (sensu Saccharomyces) -> site of polarized growth (sensu Fungi), cell cortex, cytoplasm	PHO4
YPR138C	MEP3	ammonium transport -> transport	ammonium transporter activity -> transporter activity	plasma membrane -> plasma membrane
YKL193C	SDS22	protein targeting, chromosome segregation -> cell proliferation, protein metabolism, transport	enzyme regulator activity, protein phosphatase type 1\, regulator activity -> enzyme regulator activity, hydrolase activity\, acting on ester bonds	cytoplasm, nucleus -> cytoplasm, nucleus
YKL152C	GPM1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphoglycerate mutase activity -> intramolecular transferase activity	cytosol -> cytoplasm	GCR1, GCR2, HSF1, RAP1
YDR276C	PMP3	cation transport -> transport		plasma membrane -> plasma membrane	GAT1
YIL088C	AVT7	transport -> transport	transporter activity -> transporter activity	vacuole -> cytoplasm	CBF1, SIP4
\|YIL125W\|	KGD1	tricarboxylic acid cycle, 2-oxoglutarate metabolism -> carbohydrate metabolism, ketone metabolism, organic acid metabolism, energy pathways	oxoglutarate dehydrogenase (lipoamide) activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors	mitochondrial matrix -> cytoplasm	REB1, UGA3
YMR086W	NO SYMBOL				FKH1
YNR045W	PET494	protein biosynthesis -> biosynthesis, protein metabolism	translation regulator activity -> translation regulator activity	mitochondrial inner membrane -> cytoplasm, inner membrane
\|YPL221W\|	BOP1				CBF1
Main:		transport (0.38)	transporter activity (0.33)	cytoplasm (0.69)	CBF1 RAP1 (0.18)
Score:		0.28	0.11	0.51	0.036
P-value:		6.021E-01 (energy pathways)	8.916E-01 (cation transporter activity)	8.571E-01 (cytosolic large ribosomal subunit (sensu Eukarya))	2.737E-01 (CBF1)

ORF	SYMBOL	P	F	C	TF
YIL121W	QDR2				PHO4, RAP1, SWI4
YGR254W	ENO1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphopyruvate hydratase activity -> carbon-oxygen lyase activity	phosphopyruvate hydratase complex, cytoplasm -> cytoplasm	FKH2, MSN4, PDR1, SWI5, YAP5
\|YMR181C\|	NO SYMBOL
YOL087C	NO SYMBOL				DAL82
\|YNL068C\|	FKH2	G2-specific transcription in mitotic cell cycle, pseudohyphal growth, regulation of cell cycle -> cell organization and biogenesis, cell proliferation, transcription	transcription factor activity -> DNA binding	nucleus -> nucleus	FHL1, RAP1
YKL035W	UGP1	protein amino acid glycosylation, UDP-glucose metabolism -> biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism	UTP-glucose-1-phosphate uridylyltransferase activity -> transferase activity\, transferring phosphorus-containing groups
YOR374W	ALD4	ethanol metabolism -> alcohol metabolism	aldehyde dehydrogenase (NAD+) activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors	mitochondrion -> cytoplasm	RAP1
\|YMR199W\|	CLN1	regulation of CDK activity -> cell proliferation	cyclin-dependent protein kinase\, regulator activity -> transferase activity\, transferring phosphorus-containing groups, protein kinase regulator activity	nucleus, cytoplasm -> nucleus, cytoplasm	FKH2, MBP1, NDD1, SKN7, STE12, SWI4, SWI6
YPL111W	CAR1	arginine catabolism to ornithine -> amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism	arginase activity -> hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds	cytosol -> cytoplasm	GCN4
\|YGR116W\|	SPT6	establishment and/or maintenance of chromatin architecture, regulation of transcription\, DNA-dependent, nucleosome assembly, RNA elongation from Pol II promoter -> cell organization and biogenesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	Pol II transcription elongation factor activity -> Pol II transcription elongation factor activity	nucleus, transcription elongation factor complex -> nucleus	CBF1, MSS11, RGT1, SIG1, SOK2
YAL061W	NO SYMBOL
YIL045W	PIG2		protein phosphatase regulator activity -> protein phosphatase regulator activity		CIN5
YDR100W	TVP15				RAP1
\|YPR015C\|	NO SYMBOL
YJL057C	NO SYMBOL				SRD1
YIL124W	AYR1	phosphatidic acid biosynthesis -> biosynthesis, membrane lipid metabolism, organic acid metabolism, lipid metabolism	acylglycerone-phosphate reductase activity -> oxidoreductase activity\, acting on CH-OH group of donors	endoplasmic reticulum, lipid particle, cytoplasm -> cytoplasm
Main:		alcohol metabolism (0.38)	transferase activity\, transferring phosphorus-containing groups (0.22)	cytoplasm (0.71)	RAP1 (0.36)
Score:		0.36	0.03	0.62	0.145
P-value:		7.168E-01 (alcohol metabolism)	1.043E+00 (enzyme regulator activity)	3.867E+00 (cytosol)	3.052E-01 (RAP1)